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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
COGEGGMA_00001	8.2e-68	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
COGEGGMA_00002	1.45e-104	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00003	2.62e-175	-	-	-	S	-	-	-	Putative adhesin
COGEGGMA_00004	3.41e-37	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	efflux transmembrane transporter activity
COGEGGMA_00005	3.6e-92	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00006	1.73e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_00007	1.49e-116	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00008	8.93e-119	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_00016	6.44e-194	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_00019	1.27e-72	-	-	-	S	-	-	-	Virulence protein RhuM family
COGEGGMA_00020	6.41e-156	-	-	-	L	-	-	-	IstB-like ATP binding N-terminal
COGEGGMA_00021	9.24e-16	-	-	-	L	-	-	-	IstB-like ATP binding N-terminal
COGEGGMA_00022	0.0	-	-	-	L	-	-	-	Integrase core domain
COGEGGMA_00023	6.73e-207	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
COGEGGMA_00024	3.7e-306	-	-	-	S	-	-	-	Putative transposase
COGEGGMA_00025	4.18e-13	-	-	-	-	-	-	-	-
COGEGGMA_00026	5.24e-260	-	-	-	S	-	-	-	Putative transposase
COGEGGMA_00027	1.3e-205	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_00028	0.0	-	-	-	G	-	-	-	Right handed beta helix region
COGEGGMA_00029	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COGEGGMA_00030	1.94e-76	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
COGEGGMA_00031	1.17e-174	-	-	-	CP	-	-	-	ABC-2 family transporter protein
COGEGGMA_00032	1.19e-217	-	-	-	V	ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COGEGGMA_00033	1.6e-44	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_00034	7.87e-289	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
COGEGGMA_00035	2.01e-244	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
COGEGGMA_00036	1.61e-174	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
COGEGGMA_00037	2.12e-219	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
COGEGGMA_00038	5.81e-06	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGEGGMA_00039	8.15e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00041	1.67e-93	-	-	-	S	-	-	-	conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN
COGEGGMA_00042	1.04e-76	-	-	-	S	-	-	-	Nucleotidyltransferase domain
COGEGGMA_00043	1.99e-285	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00044	2.08e-215	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COGEGGMA_00045	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
COGEGGMA_00046	4.65e-158	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COGEGGMA_00047	6.78e-42	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COGEGGMA_00048	8.76e-238	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COGEGGMA_00049	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
COGEGGMA_00050	2.16e-173	-	-	-	-	-	-	-	-
COGEGGMA_00051	8.99e-167	-	-	-	T	-	-	-	LytTr DNA-binding domain
COGEGGMA_00052	0.0	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_00053	0.0	-	-	-	-	-	-	-	-
COGEGGMA_00054	1e-309	-	-	-	V	-	-	-	COG COG0534 Na -driven multidrug efflux pump
COGEGGMA_00055	3.15e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
COGEGGMA_00056	2.07e-124	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
COGEGGMA_00057	1.21e-305	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COGEGGMA_00058	1.34e-232	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	PFAM Phosphate acetyl butaryl transferase
COGEGGMA_00059	3.17e-314	-	-	-	S	-	-	-	Belongs to the UPF0348 family
COGEGGMA_00060	1.09e-178	-	-	-	K	-	-	-	COG NOG11764 non supervised orthologous group
COGEGGMA_00061	1.51e-85	-	-	-	S	-	-	-	Ion channel
COGEGGMA_00062	1.66e-100	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
COGEGGMA_00063	6.95e-300	-	-	-	P	-	-	-	Voltage gated chloride channel
COGEGGMA_00064	6.37e-188	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_00065	2.11e-199	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
COGEGGMA_00066	3.29e-235	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
COGEGGMA_00067	2.31e-258	hisC	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_00068	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
COGEGGMA_00069	3.78e-57	-	-	-	T	ko:K07166	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00070	3.06e-195	yycJ	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00071	5.75e-141	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COGEGGMA_00072	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COGEGGMA_00073	1.61e-73	-	-	-	S	-	-	-	Putative zinc-finger
COGEGGMA_00074	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COGEGGMA_00076	4.09e-197	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	regulation of response to stimulus
COGEGGMA_00077	0.0	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
COGEGGMA_00078	2.92e-50	-	-	-	-	-	-	-	-
COGEGGMA_00079	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00080	1.03e-207	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00081	5.06e-182	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mg2 transporter protein CorA family protein
COGEGGMA_00082	9.11e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COGEGGMA_00083	2.96e-266	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00084	1.54e-308	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
COGEGGMA_00085	1.03e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
COGEGGMA_00086	0.0	cobA	1.3.1.76, 2.1.1.107, 4.2.1.75, 4.99.1.4	-	H	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00087	2.25e-211	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
COGEGGMA_00088	1.04e-110	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	precorrin-2 oxidase
COGEGGMA_00089	4.57e-293	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
COGEGGMA_00090	0.0	-	-	-	S	-	-	-	Predicted AAA-ATPase
COGEGGMA_00091	4.83e-185	-	-	-	-	-	-	-	-
COGEGGMA_00092	2.69e-165	kdpE	-	-	K	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	transcriptional regulatory protein KdpE
COGEGGMA_00093	0.0	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_00094	2.32e-152	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	system potassium uptake protein
COGEGGMA_00095	6.05e-307	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00096	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_00097	1.5e-217	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_00098	6.31e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COGEGGMA_00099	5.71e-192	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_00100	3e-147	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_00101	5.08e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
COGEGGMA_00102	1.97e-136	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_00103	4.15e-131	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_00104	2.16e-241	sdpI	-	-	S	-	-	-	SdpI/YhfL protein family
COGEGGMA_00105	3.83e-61	czrA	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_00106	3.47e-147	-	-	-	C	-	-	-	4Fe-4S single cluster domain
COGEGGMA_00107	1.49e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
COGEGGMA_00108	2.01e-208	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00109	4.71e-316	-	-	-	K	ko:K00375	-	ko00000,ko03000	Transcriptional regulator, GntR family
COGEGGMA_00110	2.7e-146	cobH	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00111	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
COGEGGMA_00112	9.42e-259	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00113	3.05e-229	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
COGEGGMA_00114	0.0	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
COGEGGMA_00115	0.0	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-6B methylase decarboxylase cbiT cbiE
COGEGGMA_00116	2.31e-175	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00117	6.98e-265	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
COGEGGMA_00118	8.69e-183	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C11-methyltransferase
COGEGGMA_00119	2.28e-272	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
COGEGGMA_00120	4.27e-308	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_00121	6.54e-219	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COGEGGMA_00122	2.2e-174	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
COGEGGMA_00123	1.12e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COGEGGMA_00124	2.58e-54	-	-	-	-	-	-	-	-
COGEGGMA_00125	6.57e-136	-	-	-	J	-	-	-	Putative rRNA methylase
COGEGGMA_00126	2.14e-158	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COGEGGMA_00127	1.03e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COGEGGMA_00128	6.24e-83	-	-	-	T	-	-	-	Bacterial SH3 domain
COGEGGMA_00129	9.18e-242	-	-	-	O	ko:K07402	-	ko00000	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family
COGEGGMA_00130	6.32e-274	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
COGEGGMA_00131	4.71e-142	yedF	-	-	O	ko:K04085	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	DsrE/DsrF-like family
COGEGGMA_00132	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_00133	3.57e-125	-	-	-	T	-	-	-	domain protein
COGEGGMA_00134	3.26e-130	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
COGEGGMA_00136	1.18e-10	-	-	-	P	-	-	-	COG COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
COGEGGMA_00137	1.79e-58	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00138	1.72e-288	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_00139	1.58e-41	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00140	0.0	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_00141	8.53e-136	-	-	-	S	-	-	-	Proteasome subunit
COGEGGMA_00142	1.46e-237	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
COGEGGMA_00143	9.66e-46	-	-	-	IQ	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00144	1.49e-295	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COGEGGMA_00145	0.0	-	-	-	Q	-	-	-	Belongs to the ATP-dependent AMP-binding enzyme family
COGEGGMA_00146	1.15e-237	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
COGEGGMA_00147	0.0	-	-	-	M	-	-	-	MBOAT, membrane-bound O-acyltransferase family
COGEGGMA_00148	1.25e-150	-	-	-	-	-	-	-	-
COGEGGMA_00149	8.69e-185	-	-	-	V	-	-	-	Vancomycin resistance protein
COGEGGMA_00150	1.39e-152	-	-	-	-	-	-	-	-
COGEGGMA_00151	6.06e-207	-	-	-	S	-	-	-	Putative cell wall binding repeat
COGEGGMA_00152	6.65e-153	-	-	-	S	-	-	-	IA, variant 3
COGEGGMA_00153	9.47e-79	-	-	-	T	-	-	-	Histidine Phosphotransfer domain
COGEGGMA_00154	1.15e-287	degQ	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
COGEGGMA_00155	0.0	-	-	-	S	-	-	-	Listeria-Bacteroides repeat domain (List_Bact_rpt)
COGEGGMA_00156	4.8e-139	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Psort location CytoplasmicMembrane, score
COGEGGMA_00157	0.0	-	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
COGEGGMA_00158	8.43e-301	hacA	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COGEGGMA_00159	3.24e-113	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COGEGGMA_00160	2.34e-303	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COGEGGMA_00161	7.39e-113	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COGEGGMA_00162	6.35e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
COGEGGMA_00163	1.12e-103	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
COGEGGMA_00164	2.82e-197	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
COGEGGMA_00165	1.41e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00166	1.42e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF1254)
COGEGGMA_00168	7.32e-130	-	2.7.8.41	-	I	ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COGEGGMA_00169	1.43e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00170	8.19e-244	-	-	-	T	-	-	-	CytoplasmicMembrane, score 9.49
COGEGGMA_00171	5.44e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_00172	0.0	-	-	-	I	ko:K06132	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes
COGEGGMA_00173	1.69e-93	-	-	-	-	-	-	-	-
COGEGGMA_00174	0.0	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
COGEGGMA_00175	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COGEGGMA_00176	5.46e-161	-	2.7.6.5	-	T	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_00177	4.92e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	COG COG3049 Penicillin V acylase and related amidases
COGEGGMA_00178	6.99e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00179	2.26e-55	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00180	1.08e-95	-	-	-	S	-	-	-	COG NOG34358 non supervised orthologous group
COGEGGMA_00181	5.4e-106	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
COGEGGMA_00182	3.71e-190	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
COGEGGMA_00183	1.54e-174	-	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
COGEGGMA_00184	1.07e-197	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00186	9e-186	-	-	-	-	-	-	-	-
COGEGGMA_00187	3.81e-224	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00188	1.87e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
COGEGGMA_00189	1.11e-113	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00190	2.07e-214	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	chromosome partitioning protein
COGEGGMA_00191	1.32e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Psort location Cytoplasmic, score 8.87
COGEGGMA_00192	3.92e-212	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00193	2.68e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00194	7.14e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
COGEGGMA_00195	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
COGEGGMA_00196	6.34e-27	-	-	-	-	-	-	-	-
COGEGGMA_00197	1.47e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00198	3.28e-198	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00199	4.06e-84	-	-	-	S	-	-	-	COG NOG33085 non supervised orthologous group
COGEGGMA_00200	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00201	0.0	-	-	-	M	-	-	-	Psort location Extracellular, score 9.55
COGEGGMA_00202	1.33e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF4315)
COGEGGMA_00203	3.37e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
COGEGGMA_00204	7.06e-40	-	-	-	-	-	-	-	-
COGEGGMA_00205	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Psort location Cytoplasmic, score 8.87
COGEGGMA_00206	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00207	2.9e-225	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00208	8.54e-40	-	-	-	S	-	-	-	Putative tranposon-transfer assisting protein
COGEGGMA_00209	7.63e-85	-	-	-	S	-	-	-	Cysteine-rich VLP
COGEGGMA_00210	2.9e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00211	8.33e-316	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00212	8.03e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00213	5.24e-73	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_00214	3.61e-41	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
COGEGGMA_00215	1.56e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_00216	2.64e-213	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_00217	4.41e-163	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_00218	9.96e-216	bcrA	-	-	V	ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_00219	1.47e-111	-	-	-	S	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_00220	4.54e-158	-	-	-	V	ko:K19310,ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_00221	8.9e-96	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_00222	1.23e-56	-	-	-	S	-	-	-	Helix-turn-helix domain
COGEGGMA_00223	3.3e-43	-	-	-	S	-	-	-	Excisionase from transposon Tn916
COGEGGMA_00224	1.33e-286	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00225	1.51e-233	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COGEGGMA_00226	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
COGEGGMA_00227	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type uncharacterized transport system
COGEGGMA_00228	1.03e-184	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00229	4.57e-246	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
COGEGGMA_00230	1.69e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
COGEGGMA_00231	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COGEGGMA_00232	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COGEGGMA_00233	8.75e-193	jag	-	-	S	ko:K06346	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00234	3.93e-289	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
COGEGGMA_00235	1.52e-47	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
COGEGGMA_00236	6.74e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COGEGGMA_00237	1.37e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
COGEGGMA_00238	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COGEGGMA_00239	1.83e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COGEGGMA_00240	4.45e-42	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	Psort location Cytoplasmic, score 8.87
COGEGGMA_00241	2.51e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COGEGGMA_00242	0.0	SpoVK	-	-	O	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00243	3.77e-217	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COGEGGMA_00244	1.84e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
COGEGGMA_00245	9.78e-156	spoT	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00246	1.14e-200	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Psort location Cytoplasmic, score 9.98
COGEGGMA_00247	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
COGEGGMA_00248	9.98e-140	-	-	-	S	-	-	-	Flavin reductase-like protein
COGEGGMA_00249	0.0	-	-	-	L	-	-	-	COG NOG25267 non supervised orthologous group
COGEGGMA_00250	0.0	-	-	-	L	-	-	-	COG NOG25267 non supervised orthologous group
COGEGGMA_00251	1.45e-35	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
COGEGGMA_00252	2.35e-285	-	-	-	L	-	-	-	Transposase IS116/IS110/IS902 family
COGEGGMA_00253	1.53e-25	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
COGEGGMA_00254	1.75e-84	gloA	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00255	4.98e-85	yccF	-	-	S	-	-	-	Inner membrane component domain
COGEGGMA_00256	1.21e-63	-	-	-	-	-	-	-	-
COGEGGMA_00257	1.92e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3789)
COGEGGMA_00258	1.14e-69	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
COGEGGMA_00259	0.0	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_00260	1.73e-89	-	-	-	C	-	-	-	Produces ATP from ADP in the presence of a proton gradient across the membrane
COGEGGMA_00261	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COGEGGMA_00262	8.05e-197	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COGEGGMA_00263	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COGEGGMA_00264	4.29e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGEGGMA_00265	1.94e-91	-	-	-	C	-	-	-	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COGEGGMA_00266	1.25e-56	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGEGGMA_00267	3.65e-172	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
COGEGGMA_00268	7.79e-93	-	-	-	-	-	-	-	-
COGEGGMA_00269	2.9e-56	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
COGEGGMA_00270	1.06e-257	rbsB_4	-	-	G	-	-	-	COG COG1879 ABC-type sugar transport system, periplasmic component
COGEGGMA_00271	5.46e-169	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
COGEGGMA_00272	0.0	ybhJ	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_00273	2.97e-63	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00274	1.85e-136	-	-	-	-	-	-	-	-
COGEGGMA_00275	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COGEGGMA_00276	1.33e-255	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
COGEGGMA_00277	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
COGEGGMA_00278	6.78e-316	-	-	-	EK	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00279	7.51e-23	-	-	-	-	-	-	-	-
COGEGGMA_00280	1.89e-294	-	-	-	G	-	-	-	Phosphodiester glycosidase
COGEGGMA_00281	2.83e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
COGEGGMA_00282	5.14e-42	-	-	-	-	-	-	-	-
COGEGGMA_00283	5.51e-205	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
COGEGGMA_00284	4.8e-223	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
COGEGGMA_00285	4.59e-226	yjfF	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Branched-chain amino acid transport system / permease component
COGEGGMA_00286	7.39e-233	ytfT	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Branched-chain amino acid transport system / permease component
COGEGGMA_00287	0.0	araG_1	3.6.3.17	-	G	ko:K02056,ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type sugar transport system, ATPase component
COGEGGMA_00288	4.22e-244	-	-	-	G	ko:K02058	-	ko00000,ko00002,ko02000	Periplasmic binding protein domain
COGEGGMA_00289	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COGEGGMA_00290	0.0	-	-	-	KT	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_00291	0.0	atsB	-	-	C	-	-	-	Radical SAM domain protein
COGEGGMA_00292	1.64e-123	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00293	2.21e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COGEGGMA_00294	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
COGEGGMA_00295	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single Cache-like
COGEGGMA_00296	1.05e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
COGEGGMA_00297	2.49e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COGEGGMA_00298	3.6e-192	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00299	2.03e-190	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
COGEGGMA_00300	1.86e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG COG0226 ABC-type phosphate transport system, periplasmic component
COGEGGMA_00301	2.29e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00302	2.3e-213	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_00303	8.68e-278	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COGEGGMA_00304	1.94e-91	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
COGEGGMA_00305	5.6e-81	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
COGEGGMA_00306	2.25e-157	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_00307	1.6e-194	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_00308	8.3e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_00309	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_00310	2.24e-204	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COGEGGMA_00311	6.7e-141	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	UreA amidohydrolase (urease) regulatory and maturation protein UreG
COGEGGMA_00312	3.83e-163	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COGEGGMA_00313	5.43e-114	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
COGEGGMA_00314	3.75e-119	-	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
COGEGGMA_00316	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
COGEGGMA_00317	3.91e-82	ureB	3.5.1.5	-	E	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
COGEGGMA_00318	1.77e-62	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
COGEGGMA_00319	8.63e-165	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_00320	0.0	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_00321	2.89e-151	-	-	-	G	ko:K10709	-	ko00000	Xylose isomerase-like TIM barrel
COGEGGMA_00322	7.54e-262	-	-	-	L	-	-	-	COG COG3547 Transposase and inactivated derivatives
COGEGGMA_00323	2.7e-12	-	-	-	G	ko:K10709	-	ko00000	Xylose isomerase-like TIM barrel
COGEGGMA_00324	4.51e-260	-	-	-	M	-	-	-	SIS domain
COGEGGMA_00325	4.79e-219	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
COGEGGMA_00326	1.16e-240	-	-	-	M	-	-	-	SIS domain
COGEGGMA_00327	0.0	-	-	-	S	-	-	-	Short chain fatty acid transporter
COGEGGMA_00328	0.0	-	-	-	S	-	-	-	Amidohydrolase family
COGEGGMA_00329	2.98e-157	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
COGEGGMA_00330	0.0	-	-	-	G	-	-	-	Right handed beta helix region
COGEGGMA_00331	3.65e-316	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_00332	1.46e-24	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00333	4.34e-241	-	-	-	S	-	-	-	Periplasmic copper-binding protein (NosD)
COGEGGMA_00334	4.88e-263	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_00335	1.6e-155	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
COGEGGMA_00336	6.86e-170	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
COGEGGMA_00337	3.71e-232	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_00338	1.89e-151	-	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
COGEGGMA_00339	3.1e-16	cysD	1.8.4.10, 1.8.4.8, 2.7.7.4	-	EH	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	PFAM Phosphoadenosine phosphosulfate reductase
COGEGGMA_00340	4.89e-105	-	-	-	S	-	-	-	Coat F domain
COGEGGMA_00341	5.48e-315	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00342	1.05e-92	-	-	-	S	-	-	-	SseB protein N-terminal domain
COGEGGMA_00343	1.61e-64	-	-	-	S	-	-	-	Putative heavy-metal-binding
COGEGGMA_00344	1.28e-139	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COGEGGMA_00345	1.35e-299	mleN_2	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00346	2.85e-194	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00347	1.96e-145	-	-	-	-	-	-	-	-
COGEGGMA_00348	1.16e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
COGEGGMA_00350	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
COGEGGMA_00351	1.05e-168	-	-	-	-	-	-	-	-
COGEGGMA_00352	0.0	-	-	-	-	-	-	-	-
COGEGGMA_00353	6.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF3786)
COGEGGMA_00354	4.34e-209	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
COGEGGMA_00355	3.6e-241	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria C-term(DUF2220)
COGEGGMA_00356	5.59e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COGEGGMA_00357	3.57e-112	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.96
COGEGGMA_00358	2.59e-152	yuaJ	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
COGEGGMA_00359	1.54e-71	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Psort location Cytoplasmic, score 8.87
COGEGGMA_00360	2.09e-68	-	-	-	-	-	-	-	-
COGEGGMA_00361	7.65e-208	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
COGEGGMA_00362	1.07e-134	-	-	-	S	ko:K01992,ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_00363	4.3e-101	-	-	-	-	-	-	-	-
COGEGGMA_00364	9.51e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00365	1.01e-91	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COGEGGMA_00366	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Cache domain
COGEGGMA_00367	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_00368	0.0	-	-	-	G	-	-	-	Hypothetical glycosyl hydrolase 6
COGEGGMA_00369	1.1e-313	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_00370	7.18e-190	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00371	1.47e-137	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00372	2.76e-270	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
COGEGGMA_00373	5.13e-187	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00374	3.85e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
COGEGGMA_00375	7.24e-207	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Glycerate kinase family
COGEGGMA_00376	1.32e-200	-	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
COGEGGMA_00377	4.49e-118	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
COGEGGMA_00378	2.15e-209	-	-	-	K	-	-	-	Transcriptional regulator
COGEGGMA_00379	6.32e-169	-	-	-	K	ko:K05799	-	ko00000,ko03000	Transcriptional regulator, GntR family
COGEGGMA_00380	7.41e-46	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	GntP family permease
COGEGGMA_00381	1.3e-87	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	GntP family permease
COGEGGMA_00382	0.0	ilvD3	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
COGEGGMA_00383	2.01e-269	-	2.7.1.45	-	H	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
COGEGGMA_00384	5.05e-146	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
COGEGGMA_00385	8.57e-156	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_00386	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
COGEGGMA_00387	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
COGEGGMA_00388	3.45e-206	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport systems
COGEGGMA_00389	7.99e-189	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system, permease component
COGEGGMA_00390	5.24e-193	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_00391	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_00392	0.0	-	-	-	G	-	-	-	beta-galactosidase
COGEGGMA_00393	7.27e-211	-	-	-	K	-	-	-	Cupin domain
COGEGGMA_00394	1.83e-298	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
COGEGGMA_00395	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_00396	0.0	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_00397	1.31e-268	-	-	-	K	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	ko00000,ko00001,ko00002,ko02000,ko02035	purine nucleotide biosynthetic process
COGEGGMA_00398	1.3e-211	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
COGEGGMA_00399	0.0	-	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_00400	9.07e-211	-	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
COGEGGMA_00401	1.95e-160	-	-	-	E	-	-	-	BMC domain
COGEGGMA_00402	4.78e-110	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00403	1.26e-244	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
COGEGGMA_00404	1.27e-185	cysT	-	-	P	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfate ABC transporter, permease protein CysT
COGEGGMA_00405	1.16e-179	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	sulfate ABC transporter
COGEGGMA_00406	8.88e-246	cysA	3.6.3.25	-	E	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_00407	0.0	aprA	1.8.99.2	-	C	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COGEGGMA_00408	1.26e-75	-	1.8.99.2	-	C	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
COGEGGMA_00409	1.27e-270	cysD	1.8.4.10, 1.8.4.8, 2.7.7.4	-	EH	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	PFAM Phosphoadenosine phosphosulfate reductase
COGEGGMA_00410	0.0	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
COGEGGMA_00411	7.3e-59	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00413	1.76e-156	-	-	-	E	-	-	-	FMN binding
COGEGGMA_00415	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00416	2.4e-257	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COGEGGMA_00417	9.69e-42	-	-	-	S	-	-	-	Psort location
COGEGGMA_00418	5.96e-152	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COGEGGMA_00419	1.21e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COGEGGMA_00420	1.58e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COGEGGMA_00421	0.0	-	-	-	M	-	-	-	Periplasmic copper-binding protein (NosD)
COGEGGMA_00422	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGEGGMA_00423	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGEGGMA_00424	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
COGEGGMA_00425	2.62e-200	-	-	-	T	-	-	-	Serine/threonine phosphatases, family 2C, catalytic domain
COGEGGMA_00426	5.9e-298	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00427	6.05e-212	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
COGEGGMA_00428	1.32e-228	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
COGEGGMA_00429	1.62e-26	-	-	-	-	-	-	-	-
COGEGGMA_00430	4.34e-90	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COGEGGMA_00431	6.62e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COGEGGMA_00432	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COGEGGMA_00433	3.22e-289	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COGEGGMA_00434	2.11e-140	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00435	2.33e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00436	3.48e-288	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_00437	3.37e-228	-	-	-	O	-	-	-	DnaB-like helicase C terminal domain
COGEGGMA_00438	2e-41	-	-	-	-	-	-	-	-
COGEGGMA_00439	9.79e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF5348)
COGEGGMA_00440	1.57e-268	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00441	1.03e-79	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_00442	2.65e-84	-	-	-	-	-	-	-	-
COGEGGMA_00443	5.79e-170	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_00444	4.11e-62	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_00445	1.32e-160	-	-	-	M	-	-	-	Psort location Cellwall, score
COGEGGMA_00447	9.24e-119	-	-	-	C	-	-	-	nitroreductase
COGEGGMA_00448	1.18e-219	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00449	1.06e-105	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
COGEGGMA_00450	1.34e-108	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
COGEGGMA_00451	1.44e-228	CbpA	-	-	O	ko:K05516	-	ko00000,ko03036,ko03110	Psort location Cytoplasmic, score
COGEGGMA_00452	1.26e-212	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
COGEGGMA_00453	2.23e-283	mdh	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00454	4.05e-93	-	-	-	S	-	-	-	Psort location
COGEGGMA_00455	7.66e-225	-	-	-	S	-	-	-	Bacterial SH3 domain homologues
COGEGGMA_00456	1.35e-211	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
COGEGGMA_00457	2.4e-268	-	-	-	H	-	-	-	Uroporphyrinogen decarboxylase (URO-D)
COGEGGMA_00458	2.32e-194	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Pterin binding enzyme
COGEGGMA_00459	5.21e-138	-	-	-	S	-	-	-	B12 binding domain
COGEGGMA_00460	0.0	-	-	-	C	-	-	-	Domain of unknown function (DUF4445)
COGEGGMA_00461	2.61e-133	-	-	-	S	-	-	-	Predicted metal-binding protein (DUF2284)
COGEGGMA_00462	3.41e-143	-	2.1.1.13	-	S	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
COGEGGMA_00463	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
COGEGGMA_00464	1.06e-126	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COGEGGMA_00465	6.23e-267	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
COGEGGMA_00466	4.75e-250	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COGEGGMA_00467	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00468	1.76e-185	-	-	-	M	-	-	-	Glycosyltransferase like family 2
COGEGGMA_00469	0.0	-	-	-	G	ko:K13663	-	ko00000,ko01000	nodulation
COGEGGMA_00470	0.0	-	-	-	IM	-	-	-	Cytidylyltransferase-like
COGEGGMA_00471	0.0	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
COGEGGMA_00472	6.94e-283	licD	-	-	M	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	LICD family
COGEGGMA_00473	0.0	-	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
COGEGGMA_00474	6.62e-176	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
COGEGGMA_00475	2.09e-45	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COGEGGMA_00476	1.44e-38	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
COGEGGMA_00477	3.32e-119	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
COGEGGMA_00478	3.14e-89	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COGEGGMA_00479	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COGEGGMA_00480	8.45e-238	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_00481	3.84e-162	-	-	-	L	-	-	-	COG COG2963 Transposase and inactivated derivatives
COGEGGMA_00482	2.51e-173	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
COGEGGMA_00483	7.39e-53	-	-	-	-	-	-	-	-
COGEGGMA_00484	8.68e-129	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00485	7.82e-97	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
COGEGGMA_00486	6.76e-40	-	-	-	-	-	-	-	-
COGEGGMA_00487	3.63e-42	-	-	-	S	-	-	-	HEPN domain
COGEGGMA_00488	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COGEGGMA_00489	2.79e-107	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COGEGGMA_00490	1.95e-109	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
COGEGGMA_00491	1.05e-101	-	-	-	S	-	-	-	MOSC domain
COGEGGMA_00492	6.89e-185	ycfH	-	-	L	ko:K03424	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00493	0.0	capA	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
COGEGGMA_00494	3.05e-96	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00495	2.85e-266	-	-	-	F	-	-	-	Phosphoribosyl transferase
COGEGGMA_00496	7.71e-255	-	-	-	J	-	-	-	PELOTA RNA binding domain
COGEGGMA_00497	3.69e-231	-	-	-	G	-	-	-	C-C_Bond_Lyase of the TIM-Barrel fold
COGEGGMA_00498	0.0	-	-	-	S	-	-	-	Putative component of 'biosynthetic module'
COGEGGMA_00499	1.02e-258	-	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
COGEGGMA_00500	1.2e-137	terD_2	-	-	T	ko:K05795	-	ko00000	TerD domain
COGEGGMA_00501	3.1e-137	-	-	-	T	ko:K05795	-	ko00000	TerD domain
COGEGGMA_00502	1.78e-145	yceC	-	-	T	-	-	-	TerD domain
COGEGGMA_00503	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
COGEGGMA_00504	8.41e-176	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COGEGGMA_00505	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
COGEGGMA_00506	3.15e-145	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
COGEGGMA_00507	3.03e-134	atpD	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane
COGEGGMA_00508	0.0	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
COGEGGMA_00509	0.0	ntpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
COGEGGMA_00510	2.16e-129	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00511	5.62e-69	-	-	-	C	ko:K02122	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.87
COGEGGMA_00512	1.37e-84	-	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00513	0.0	ntpI	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
COGEGGMA_00514	1.68e-252	ntpC	-	-	C	ko:K02119	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Archaeal vacuolar-type H -ATPase subunit C
COGEGGMA_00515	1.2e-41	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00516	1.51e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COGEGGMA_00518	0.0	-	-	-	I	ko:K06132	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
COGEGGMA_00519	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
COGEGGMA_00520	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
COGEGGMA_00521	1.58e-49	-	-	-	-	-	-	-	-
COGEGGMA_00522	6.91e-45	-	-	-	-	-	-	-	-
COGEGGMA_00523	1.55e-38	-	-	-	-	-	-	-	-
COGEGGMA_00524	1.16e-265	-	-	-	L	-	-	-	Arm DNA-binding domain
COGEGGMA_00525	3.26e-88	-	-	-	-	-	-	-	-
COGEGGMA_00526	6.11e-188	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
COGEGGMA_00527	4.5e-200	-	-	-	K	-	-	-	ParB-like nuclease domain
COGEGGMA_00528	1.68e-228	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
COGEGGMA_00530	5.32e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00531	5.32e-43	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00532	9.46e-68	-	-	-	-	-	-	-	-
COGEGGMA_00533	5.22e-227	-	-	-	L	-	-	-	PFAM transposase IS4 family protein
COGEGGMA_00534	6.78e-162	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_00535	3.61e-202	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00536	5.14e-93	-	-	-	N	-	-	-	repeat protein
COGEGGMA_00537	5.94e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00538	3.23e-218	-	-	-	V	-	-	-	Abi-like protein
COGEGGMA_00539	0.0	-	-	-	N	-	-	-	repeat protein
COGEGGMA_00540	0.0	parE	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	TopoisomeraseII
COGEGGMA_00541	0.0	gyrA_1	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
COGEGGMA_00542	9.83e-106	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
COGEGGMA_00543	1.78e-254	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
COGEGGMA_00544	4.94e-58	ylxR	-	-	K	ko:K07742	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00545	4.9e-64	-	-	-	J	-	-	-	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
COGEGGMA_00546	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COGEGGMA_00547	4.61e-84	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COGEGGMA_00548	4.01e-235	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
COGEGGMA_00549	1.59e-212	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COGEGGMA_00550	1e-217	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
COGEGGMA_00551	8.72e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COGEGGMA_00552	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
COGEGGMA_00553	1.4e-113	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COGEGGMA_00554	4.95e-120	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_00555	4.59e-292	fabV	1.3.1.44, 1.3.1.9	-	I	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)
COGEGGMA_00556	0.0	-	-	-	O	-	-	-	Papain family cysteine protease
COGEGGMA_00557	1.03e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1292)
COGEGGMA_00558	8.45e-191	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
COGEGGMA_00559	0.0	-	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
COGEGGMA_00560	1.68e-141	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00561	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COGEGGMA_00562	3.55e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
COGEGGMA_00563	1.84e-125	-	-	-	-	-	-	-	-
COGEGGMA_00564	0.0	-	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16C associated
COGEGGMA_00565	2.37e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COGEGGMA_00566	4.31e-179	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
COGEGGMA_00567	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
COGEGGMA_00568	7.09e-258	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
COGEGGMA_00569	2.93e-177	-	-	-	E	-	-	-	Pfam:AHS1
COGEGGMA_00570	1.25e-241	kipA	-	-	E	ko:K06350	-	ko00000	Pfam:AHS2
COGEGGMA_00571	1.17e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COGEGGMA_00572	5.45e-312	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	acetyl-CoA carboxylase, biotin carboxylase
COGEGGMA_00573	6.85e-179	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
COGEGGMA_00574	3.67e-149	-	-	-	F	-	-	-	Cytidylate kinase-like family
COGEGGMA_00575	4.02e-237	bcsP	-	-	S	ko:K07080	-	ko00000	TRAP transporter solute receptor, TAXI family
COGEGGMA_00576	0.0	-	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
COGEGGMA_00577	6.39e-233	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COGEGGMA_00578	6.91e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COGEGGMA_00579	3.65e-220	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COGEGGMA_00580	1.02e-291	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
COGEGGMA_00581	1.71e-190	-	-	-	K	-	-	-	Domain of unknown function (DUF3825)
COGEGGMA_00582	1.96e-252	-	-	-	I	-	-	-	Acyltransferase family
COGEGGMA_00583	1.53e-161	-	-	-	-	-	-	-	-
COGEGGMA_00584	1.59e-302	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00585	0.0	-	-	-	-	-	-	-	-
COGEGGMA_00586	2.31e-297	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
COGEGGMA_00587	4.07e-175	ssuC_2	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_00588	1.9e-180	ssuB_2	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ABC-type nitrate sulfonate bicarbonate transport system ATPase component
COGEGGMA_00589	1.69e-234	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COGEGGMA_00590	5.9e-137	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
COGEGGMA_00591	1.05e-222	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatidylserine decarboxylase
COGEGGMA_00592	3.33e-153	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COGEGGMA_00593	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_00594	1.58e-264	asd	1.2.1.11	-	C	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00595	8e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
COGEGGMA_00596	3.76e-249	selD	2.7.9.3	-	H	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
COGEGGMA_00597	7.72e-178	fnt	-	-	P	ko:K02598	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00598	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase III
COGEGGMA_00599	4.94e-142	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
COGEGGMA_00600	2.94e-184	-	-	-	S	-	-	-	TraX protein
COGEGGMA_00601	6.9e-166	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00602	7.85e-241	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00603	5.75e-147	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Methyltransferase domain protein
COGEGGMA_00604	8.68e-44	-	-	-	-	-	-	-	-
COGEGGMA_00607	1.38e-303	-	-	-	U	-	-	-	Leucine rich repeats (6 copies)
COGEGGMA_00608	9.62e-20	-	-	-	N	-	-	-	endoglucanase-related protein, glucosyl hydrolase family 9 protein
COGEGGMA_00609	4.55e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00610	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
COGEGGMA_00611	2.25e-194	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	nlpA lipoprotein
COGEGGMA_00612	2.63e-135	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG COG2011 ABC-type metal ion transport system, permease component
COGEGGMA_00613	9.18e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COGEGGMA_00614	2.19e-56	-	-	-	-	-	-	-	-
COGEGGMA_00615	2.04e-31	-	-	-	-	-	-	-	-
COGEGGMA_00616	2.13e-167	-	-	-	-	-	-	-	-
COGEGGMA_00617	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
COGEGGMA_00618	1.96e-202	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00619	4.88e-198	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
COGEGGMA_00620	3.88e-73	-	-	-	S	ko:K21600	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00621	7.08e-49	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00622	4.41e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COGEGGMA_00623	0.0	-	-	-	G	-	-	-	Periplasmic binding protein domain
COGEGGMA_00624	6.36e-134	-	-	-	K	-	-	-	regulation of single-species biofilm formation
COGEGGMA_00625	9.84e-180	-	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
COGEGGMA_00626	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF1727)
COGEGGMA_00627	1.32e-216	-	-	-	C	-	-	-	glycerophosphoryl diester phosphodiesterase
COGEGGMA_00628	1.28e-115	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
COGEGGMA_00629	5.58e-221	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGEGGMA_00630	5.13e-138	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COGEGGMA_00631	2.78e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COGEGGMA_00632	2.1e-78	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COGEGGMA_00633	4.24e-10	-	3.4.19.11	-	EM	ko:K01308	-	ko00000,ko01000,ko01002	Zn_pept
COGEGGMA_00634	6.74e-42	-	-	-	KT	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00635	6.6e-46	-	-	-	K	-	-	-	Penicillinase repressor
COGEGGMA_00636	4.86e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COGEGGMA_00637	3.05e-184	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_00638	4.7e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COGEGGMA_00639	1.31e-302	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COGEGGMA_00640	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COGEGGMA_00641	1.2e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
COGEGGMA_00642	1.46e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COGEGGMA_00643	1.22e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COGEGGMA_00644	1.21e-109	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COGEGGMA_00645	8.56e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COGEGGMA_00646	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COGEGGMA_00647	9.39e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COGEGGMA_00648	2.29e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COGEGGMA_00649	1.8e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COGEGGMA_00650	4.6e-53	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COGEGGMA_00651	1.39e-36	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
COGEGGMA_00652	1.88e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COGEGGMA_00653	3.41e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COGEGGMA_00654	5.64e-84	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COGEGGMA_00655	1.77e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COGEGGMA_00656	3.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COGEGGMA_00657	7.84e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COGEGGMA_00658	4.85e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
COGEGGMA_00659	1.77e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COGEGGMA_00660	3.91e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
COGEGGMA_00661	3.88e-234	-	-	-	U	-	-	-	Belongs to the peptidase S26 family
COGEGGMA_00662	1.27e-50	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
COGEGGMA_00663	3.83e-232	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
COGEGGMA_00664	2.01e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
COGEGGMA_00665	3.2e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
COGEGGMA_00666	8.08e-100	-	-	-	S	ko:K06404	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_00667	2.93e-107	spoVAC	-	-	S	ko:K06405	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_00668	1.86e-267	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
COGEGGMA_00669	1.33e-79	spoVAE	-	-	S	ko:K06407	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_00670	3.6e-146	spoVAA	-	-	S	ko:K06403	-	ko00000	Psort location
COGEGGMA_00671	3.47e-109	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00673	4.08e-157	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit
COGEGGMA_00674	3.68e-97	spoIIAB	2.7.11.1	-	H	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
COGEGGMA_00675	2.76e-70	spoIIAA	-	-	T	ko:K06378	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00676	7.37e-269	-	-	-	S	-	-	-	Tetratricopeptide repeat
COGEGGMA_00677	3.2e-27	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00678	3.66e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00679	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00680	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COGEGGMA_00681	5.51e-308	-	-	-	G	-	-	-	Amidohydrolase
COGEGGMA_00682	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_00683	9e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_00684	2.11e-18	-	-	-	-	-	-	-	-
COGEGGMA_00685	0.0	-	-	-	N	-	-	-	domain, Protein
COGEGGMA_00686	4.38e-43	-	-	-	S	-	-	-	BhlA holin family
COGEGGMA_00687	5.47e-125	-	-	-	-	-	-	-	-
COGEGGMA_00688	0.0	-	-	-	V	-	-	-	Lanthionine synthetase C-like protein
COGEGGMA_00690	2.4e-166	-	-	-	L	-	-	-	COG COG4584 Transposase and inactivated derivatives
COGEGGMA_00691	2.33e-125	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_00692	1.45e-20	-	-	-	-	-	-	-	-
COGEGGMA_00693	2.95e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_00694	4.65e-158	-	-	-	T	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COGEGGMA_00695	3.96e-68	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_00696	6.98e-94	-	-	-	L	-	-	-	PFAM Integrase core domain
COGEGGMA_00697	2.51e-159	-	-	-	L	-	-	-	PFAM Integrase core domain
COGEGGMA_00698	3.12e-97	-	-	-	K	-	-	-	COG NOG16925 non supervised orthologous group
COGEGGMA_00699	1.07e-94	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
COGEGGMA_00700	3.54e-188	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	arsenical-resistance protein
COGEGGMA_00701	4.68e-71	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_00702	9.44e-170	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase iron-sulfur
COGEGGMA_00703	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	COG COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
COGEGGMA_00704	2.67e-113	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00705	1.83e-112	-	-	-	-	-	-	-	-
COGEGGMA_00706	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Heavy-metal-associated domain
COGEGGMA_00707	5.01e-80	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_00708	1.12e-213	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COGEGGMA_00709	2.74e-96	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
COGEGGMA_00711	2.47e-248	-	-	-	P	-	-	-	Citrate transporter
COGEGGMA_00712	5.09e-194	-	-	-	S	-	-	-	Cupin domain
COGEGGMA_00713	9.4e-105	-	-	-	C	-	-	-	Flavodoxin
COGEGGMA_00714	5.72e-205	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00715	3.74e-69	-	-	-	S	-	-	-	MazG-like family
COGEGGMA_00716	0.0	-	-	-	S	-	-	-	Psort location
COGEGGMA_00717	7.21e-236	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00718	5.88e-278	iadA	-	-	E	ko:K01305	-	ko00000,ko01000,ko01002	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation
COGEGGMA_00719	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COGEGGMA_00720	1.36e-242	-	-	-	KT	-	-	-	Region found in RelA / SpoT proteins
COGEGGMA_00721	2.97e-136	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_00722	1.74e-180	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00723	1.14e-227	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	Menaquinone biosynthesis
COGEGGMA_00724	1.2e-201	-	3.4.21.96	-	S	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	cellulase activity
COGEGGMA_00725	2.32e-200	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COGEGGMA_00726	3.83e-139	fchA	-	-	E	-	-	-	Formiminotransferase-cyclodeaminase
COGEGGMA_00727	8.01e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF3786)
COGEGGMA_00728	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00729	2.8e-185	acsE	2.1.1.258	-	E	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00730	0.0	acsC	2.1.1.245	-	C	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00731	3.89e-214	acsD	2.1.1.245	-	C	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	CO dehydrogenase/acetyl-CoA synthase delta subunit
COGEGGMA_00732	0.0	cdhC	2.3.1.169	-	C	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	acetyl-CoA decarbonylase synthase complex subunit beta
COGEGGMA_00733	0.0	cdhC	2.3.1.169	-	C	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	acetyl-CoA decarbonylase synthase complex subunit beta
COGEGGMA_00734	6.85e-178	cooC	-	-	D	ko:K07321	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00735	0.0	cooS1	1.2.7.4	-	C	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00736	1.83e-183	cooC1	-	-	D	ko:K07321	-	ko00000	cell division inhibitor, membrane ATPase MinD
COGEGGMA_00737	1.02e-34	-	-	-	S	-	-	-	Predicted RNA-binding protein
COGEGGMA_00738	1.16e-68	-	-	-	-	-	-	-	-
COGEGGMA_00739	1.47e-203	yvgN	-	-	S	-	-	-	Aldo keto reductases, related to diketogulonate reductase
COGEGGMA_00740	8.81e-241	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00741	8.4e-150	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COGEGGMA_00742	3.4e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
COGEGGMA_00743	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00744	1.07e-283	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
COGEGGMA_00745	1.53e-209	yfiH	-	-	S	ko:K05810	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00746	1.6e-86	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
COGEGGMA_00747	3.38e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COGEGGMA_00748	2.94e-202	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COGEGGMA_00749	1.71e-138	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
COGEGGMA_00750	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COGEGGMA_00751	5.65e-220	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_00752	1.32e-187	-	-	-	M	-	-	-	OmpA family
COGEGGMA_00753	0.0	-	-	-	U	-	-	-	MotA/TolQ/ExbB proton channel family
COGEGGMA_00754	1.25e-146	-	-	-	G	-	-	-	Phosphoglycerate mutase family
COGEGGMA_00755	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
COGEGGMA_00756	5.78e-225	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COGEGGMA_00757	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_00758	6.8e-219	pyrK_1	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_00759	7.9e-166	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_00760	1.38e-167	yebC	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00761	2.9e-310	-	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
COGEGGMA_00762	1.2e-76	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
COGEGGMA_00763	2.79e-275	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COGEGGMA_00764	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COGEGGMA_00765	6.39e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COGEGGMA_00766	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_00767	2.2e-294	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
COGEGGMA_00768	2.43e-205	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Psort location Extracellular, score
COGEGGMA_00769	3.94e-30	-	-	-	-	-	-	-	-
COGEGGMA_00770	1.14e-175	rsmJ	-	-	Q	-	-	-	Specifically methylates the guanosine in position 1516 of 16S rRNA
COGEGGMA_00771	0.0	pap	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00772	6.23e-104	-	-	-	-	-	-	-	-
COGEGGMA_00773	8.58e-71	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_00774	5.57e-74	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
COGEGGMA_00775	1.19e-08	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
COGEGGMA_00776	1.81e-62	-	-	-	-	-	-	-	-
COGEGGMA_00777	6.81e-182	aroK	2.7.1.71	-	H	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COGEGGMA_00778	4.38e-306	dacB2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_00779	1.84e-196	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00780	1.94e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COGEGGMA_00781	4.3e-189	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COGEGGMA_00782	6.61e-201	-	-	-	S	ko:K07098	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00783	3.12e-251	moeA2	-	-	H	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00784	3.46e-285	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_00785	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COGEGGMA_00786	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
COGEGGMA_00787	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COGEGGMA_00788	9.11e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COGEGGMA_00789	1.57e-201	-	-	-	M	-	-	-	Putative cell wall binding repeat
COGEGGMA_00790	1.1e-29	-	-	-	-	-	-	-	-
COGEGGMA_00791	2.51e-31	-	-	-	-	-	-	-	-
COGEGGMA_00792	5.64e-79	-	-	-	-	-	-	-	-
COGEGGMA_00793	1.49e-54	-	-	-	-	-	-	-	-
COGEGGMA_00794	4.25e-103	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
COGEGGMA_00795	5.22e-120	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
COGEGGMA_00796	0.0	rimO	2.8.4.4	-	H	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
COGEGGMA_00797	4.06e-50	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COGEGGMA_00798	3.43e-141	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
COGEGGMA_00799	7.36e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
COGEGGMA_00800	4.66e-200	yicC	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00801	0.0	FbpA	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00802	0.0	yfmM	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score
COGEGGMA_00803	5.42e-310	mepA_10	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00804	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
COGEGGMA_00805	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
COGEGGMA_00806	5.93e-261	tyrA	1.3.1.12	-	C	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00807	2.95e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COGEGGMA_00808	1.15e-234	ldhA	1.1.1.28	-	C	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_00809	6.8e-42	-	-	-	-	-	-	-	-
COGEGGMA_00810	1.28e-131	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_00811	1.57e-285	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
COGEGGMA_00812	1.72e-251	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COGEGGMA_00813	7.7e-180	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
COGEGGMA_00814	1.53e-113	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COGEGGMA_00815	3.47e-40	ylqC	-	-	S	ko:K06960	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00816	1.2e-49	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
COGEGGMA_00817	1.23e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COGEGGMA_00818	1.92e-67	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COGEGGMA_00819	9.01e-29	-	-	-	H	-	-	-	COG COG1893 Ketopantoate reductase
COGEGGMA_00820	4.1e-67	-	-	-	-	-	-	-	-
COGEGGMA_00821	1.49e-97	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00822	7.38e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF4314)
COGEGGMA_00823	4.22e-90	-	-	-	-	-	-	-	-
COGEGGMA_00825	1.85e-168	-	-	-	L	-	-	-	Recombinase
COGEGGMA_00826	1.23e-239	-	-	-	L	-	-	-	Recombinase
COGEGGMA_00827	1.66e-273	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00828	1.55e-33	-	-	-	-	-	-	-	-
COGEGGMA_00830	3.2e-226	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COGEGGMA_00831	5.14e-48	-	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COGEGGMA_00832	2.63e-134	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COGEGGMA_00833	6.9e-167	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_00834	1.28e-171	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_00835	3.44e-26	-	-	-	-	-	-	-	-
COGEGGMA_00836	2.64e-09	-	-	-	K	-	-	-	sequence-specific DNA binding
COGEGGMA_00837	1.81e-51	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_00838	7.1e-65	-	-	-	K	ko:K02477	-	ko00000,ko02022	Cytoplasmic, score 8.87
COGEGGMA_00840	6.15e-106	-	-	-	C	-	-	-	Radical SAM domain protein
COGEGGMA_00841	3.01e-35	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
COGEGGMA_00842	2.11e-125	-	-	-	V	-	-	-	abc transporter atp-binding protein
COGEGGMA_00843	3.09e-44	-	-	-	-	-	-	-	-
COGEGGMA_00845	7.08e-81	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_00846	2.68e-140	-	1.21.98.3	-	C	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	PFAM Radical SAM
COGEGGMA_00847	1.81e-215	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COGEGGMA_00848	8.13e-64	-	-	-	K	ko:K02477	-	ko00000,ko02022	Cytoplasmic, score 8.87
COGEGGMA_00850	9.33e-15	-	-	-	KOT	-	-	-	Accessory gene regulator B
COGEGGMA_00851	5.1e-100	-	-	-	K	-	-	-	SIR2-like domain
COGEGGMA_00853	1.18e-178	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_00854	0.0	araB	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00855	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
COGEGGMA_00856	9.56e-267	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Periplasmic binding protein-like domain
COGEGGMA_00857	4.47e-199	-	-	-	S	-	-	-	Sortase family
COGEGGMA_00858	0.0	-	-	-	M	-	-	-	outer membrane autotransporter barrel domain protein
COGEGGMA_00859	1.38e-91	-	-	-	S	-	-	-	Psort location
COGEGGMA_00860	1.45e-215	aguB	3.5.1.53, 3.5.1.6	-	S	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000	N-carbamoylputrescine amidase
COGEGGMA_00861	1.1e-283	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
COGEGGMA_00862	1.14e-279	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00863	8.26e-309	LYS1	1.5.1.7	-	C	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00864	9.27e-217	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
COGEGGMA_00865	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
COGEGGMA_00866	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
COGEGGMA_00867	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
COGEGGMA_00868	9.34e-225	-	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_00869	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00870	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00871	1.65e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
COGEGGMA_00872	2.42e-201	-	-	-	K	-	-	-	AraC-like ligand binding domain
COGEGGMA_00873	7.32e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
COGEGGMA_00874	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00875	0.0	-	-	-	S	-	-	-	VWA-like domain (DUF2201)
COGEGGMA_00876	5.97e-244	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00877	4.89e-176	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
COGEGGMA_00878	1.07e-120	-	-	-	K	-	-	-	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COGEGGMA_00879	4.81e-50	-	-	-	-	-	-	-	-
COGEGGMA_00880	3.52e-252	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COGEGGMA_00881	1.9e-185	-	-	-	Q	-	-	-	NOG31153 non supervised orthologous group
COGEGGMA_00882	3.95e-295	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	AMP-binding enzyme
COGEGGMA_00883	0.0	-	-	-	S	ko:K06937	-	ko00000,ko01000	Radical SAM superfamily
COGEGGMA_00884	4.81e-103	-	-	-	S	-	-	-	Putative redox-active protein (C_GCAxxG_C_C)
COGEGGMA_00885	2.06e-125	-	-	-	H	-	-	-	Hypothetical methyltransferase
COGEGGMA_00886	2.77e-49	-	-	-	-	-	-	-	-
COGEGGMA_00887	0.0	-	-	-	CE	-	-	-	Cysteine-rich domain
COGEGGMA_00888	0.0	mop	1.2.99.7	-	C	ko:K07469	-	ko00000,ko01000	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
COGEGGMA_00889	1.64e-56	-	-	-	-	-	-	-	-
COGEGGMA_00890	2.39e-226	-	-	-	S	-	-	-	MobA-like NTP transferase domain
COGEGGMA_00891	3.32e-264	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
COGEGGMA_00892	6.79e-249	pucA	-	-	O	ko:K07402	-	ko00000	XdhC and CoxI family
COGEGGMA_00893	4.06e-211	-	-	-	S	ko:K05303	-	ko00000,ko01000	Macrocin-O-methyltransferase (TylF)
COGEGGMA_00894	1.88e-258	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
COGEGGMA_00895	1.83e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COGEGGMA_00896	8.09e-193	-	3.6.3.34	-	HP	ko:K02013,ko:K09820	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_00897	3.35e-114	-	3.6.1.15	-	F	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	ko00000,ko00001,ko01000	NTPase
COGEGGMA_00899	1.86e-270	macB2	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_00900	3.83e-289	-	-	-	M	ko:K02005	-	ko00000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
COGEGGMA_00901	4.29e-171	macB	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_00902	0.0	apeA	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00903	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00904	3.12e-23	-	-	-	-	-	-	-	-
COGEGGMA_00905	1.12e-94	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_00906	8.61e-164	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD domain
COGEGGMA_00907	1.43e-48	-	-	-	-	-	-	-	-
COGEGGMA_00908	2.06e-38	-	-	-	-	-	-	-	-
COGEGGMA_00909	2.02e-43	-	-	-	S	-	-	-	FeoA domain
COGEGGMA_00910	1.1e-52	-	-	-	D	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
COGEGGMA_00911	1.7e-41	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
COGEGGMA_00912	1.19e-35	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
COGEGGMA_00913	4.1e-44	-	-	-	K	-	-	-	Periplasmic binding protein LacI transcriptional regulator
COGEGGMA_00914	1.2e-216	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
COGEGGMA_00915	4.44e-47	tctD	-	-	KT	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_00916	3.63e-48	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_00917	1.18e-141	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
COGEGGMA_00918	8.38e-85	-	-	-	U	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00919	4.52e-83	-	-	-	U	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00920	1.18e-75	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
COGEGGMA_00921	5.63e-81	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
COGEGGMA_00922	1.93e-90	-	5.1.3.30, 5.1.3.31	-	G	ko:K18910	-	ko00000,ko01000	Xylose isomerase-like TIM barrel
COGEGGMA_00923	8.33e-21	-	-	-	S	-	-	-	HEPN domain
COGEGGMA_00924	2.51e-177	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00925	4.25e-53	-	-	-	S	-	-	-	SnoaL-like domain
COGEGGMA_00926	1.35e-88	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
COGEGGMA_00927	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
COGEGGMA_00928	7.23e-93	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_00929	7.63e-169	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_00930	1.05e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_00931	7.26e-27	-	-	-	-	-	-	-	-
COGEGGMA_00932	7.8e-207	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_00933	9.6e-169	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_00934	2.56e-219	-	-	-	V	-	-	-	ABC transporter
COGEGGMA_00935	3.09e-159	-	-	-	T	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COGEGGMA_00936	7.49e-36	-	-	-	K	-	-	-	Transcriptional regulator
COGEGGMA_00937	1.99e-90	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_00938	5.91e-279	-	-	-	S	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
COGEGGMA_00939	1.2e-202	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
COGEGGMA_00940	6.12e-76	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_00941	1.02e-46	-	-	-	-	-	-	-	-
COGEGGMA_00942	1.68e-147	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
COGEGGMA_00943	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
COGEGGMA_00944	6.98e-55	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00945	4e-68	-	-	-	-	-	-	-	-
COGEGGMA_00946	6.52e-30	-	-	-	-	-	-	-	-
COGEGGMA_00947	2.13e-115	-	-	-	-	-	-	-	-
COGEGGMA_00948	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COGEGGMA_00949	7.81e-29	-	-	-	-	-	-	-	-
COGEGGMA_00950	1.45e-161	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_00951	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_00952	2.82e-139	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
COGEGGMA_00953	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
COGEGGMA_00954	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
COGEGGMA_00955	3.69e-195	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00956	1.77e-207	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00957	1.61e-282	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_00958	0.000189	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_00959	2.78e-170	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_00960	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COGEGGMA_00961	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00962	1.1e-153	-	-	-	S	-	-	-	Protein of unknown function, DUF624
COGEGGMA_00963	4.82e-188	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00964	8.19e-212	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_00965	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_00966	1.88e-219	-	-	-	K	-	-	-	PFAM AraC-like ligand binding domain
COGEGGMA_00967	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
COGEGGMA_00968	9.98e-246	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
COGEGGMA_00969	9.12e-139	-	-	-	-	-	-	-	-
COGEGGMA_00970	9.01e-86	-	-	-	-	-	-	-	-
COGEGGMA_00971	2.38e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4869)
COGEGGMA_00972	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00973	2.4e-65	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00974	1.89e-168	-	-	-	E	ko:K04477	-	ko00000	PHP domain protein
COGEGGMA_00975	9.89e-150	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_00976	2.26e-153	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_00977	1.56e-226	ytqA	-	-	S	ko:K07139	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_00978	2.95e-117	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_00979	2.29e-308	rarA	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
COGEGGMA_00980	3.19e-146	-	-	-	F	-	-	-	Cytidylate kinase-like family
COGEGGMA_00981	3.37e-160	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_00982	8.69e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_00983	4.88e-232	livM	-	-	P	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00984	3.6e-189	livH	-	-	P	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_00985	3.62e-268	braC	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
COGEGGMA_00986	3.98e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COGEGGMA_00987	6.11e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
COGEGGMA_00988	1.08e-107	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COGEGGMA_00989	1.19e-71	-	-	-	S	-	-	-	COG NOG16856 non supervised orthologous group
COGEGGMA_00990	4.37e-266	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COGEGGMA_00991	7.89e-204	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	COG1589 Cell division septal protein
COGEGGMA_00992	1.68e-313	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COGEGGMA_00993	2.38e-252	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
COGEGGMA_00994	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COGEGGMA_00995	4.74e-217	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COGEGGMA_00996	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
COGEGGMA_00997	0.0	-	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	Penicillin-binding Protein dimerisation domain
COGEGGMA_00998	9.16e-125	-	-	-	-	-	-	-	-
COGEGGMA_00999	1.27e-222	rsmH	2.1.1.199	-	H	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COGEGGMA_01000	2.79e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
COGEGGMA_01001	2.82e-237	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COGEGGMA_01002	5.7e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COGEGGMA_01003	3.39e-168	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
COGEGGMA_01004	8.05e-157	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
COGEGGMA_01005	1.86e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COGEGGMA_01006	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
COGEGGMA_01007	2.3e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	serine threonine protein phosphatase
COGEGGMA_01008	2.2e-252	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COGEGGMA_01009	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COGEGGMA_01010	2.17e-149	yugP	-	-	S	ko:K06973	-	ko00000	Psort location CytoplasmicMembrane, score 9.26
COGEGGMA_01011	4.64e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COGEGGMA_01012	1.18e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COGEGGMA_01013	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COGEGGMA_01014	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COGEGGMA_01015	0.0	-	-	-	-	-	-	-	-
COGEGGMA_01016	2.85e-214	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
COGEGGMA_01017	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01018	5.7e-190	-	-	-	-	-	-	-	-
COGEGGMA_01019	1.59e-244	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_01020	1.82e-97	-	-	-	S	-	-	-	CBS domain
COGEGGMA_01021	4.94e-218	-	-	-	S	-	-	-	Sodium Bile acid symporter family
COGEGGMA_01022	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC-type polar amino acid transport system ATPase component
COGEGGMA_01023	1.22e-157	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01024	2.85e-180	artP	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
COGEGGMA_01025	7.91e-204	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COGEGGMA_01026	1.17e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01027	2.52e-153	ygaZ	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01028	3.84e-215	-	-	-	E	-	-	-	Listeria-Bacteroides repeat domain (List_Bact_rpt)
COGEGGMA_01029	6.37e-102	-	-	-	P	-	-	-	Ferric uptake regulator family
COGEGGMA_01031	1.13e-191	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01032	2.23e-314	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01033	3.9e-269	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COGEGGMA_01034	4.96e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COGEGGMA_01035	4.8e-99	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01036	1.62e-95	-	-	-	S	-	-	-	ACT domain protein
COGEGGMA_01037	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	TIGRFAM anaerobic ribonucleoside-triphosphate reductase
COGEGGMA_01038	1.25e-284	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COGEGGMA_01039	5.16e-248	-	-	-	S	-	-	-	Tetratricopeptide repeat
COGEGGMA_01040	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COGEGGMA_01041	2.1e-218	-	-	-	M	-	-	-	Nucleotidyl transferase
COGEGGMA_01042	6.28e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COGEGGMA_01043	8.05e-231	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COGEGGMA_01044	7.04e-221	prmC	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01045	1.02e-46	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
COGEGGMA_01046	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COGEGGMA_01047	3.75e-109	-	-	-	S	-	-	-	small multi-drug export protein
COGEGGMA_01048	1.7e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COGEGGMA_01049	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score 10.00
COGEGGMA_01050	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Putative carbohydrate binding domain
COGEGGMA_01051	1.47e-241	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
COGEGGMA_01052	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
COGEGGMA_01053	2.44e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01054	3.53e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01055	1.78e-208	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
COGEGGMA_01056	2.85e-153	metV	-	-	C	-	-	-	Methylene-tetrahydrofolate reductase C terminal
COGEGGMA_01057	0.0	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
COGEGGMA_01059	2.32e-144	-	-	-	K	ko:K07694	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
COGEGGMA_01060	2.2e-308	-	-	-	T	-	-	-	Psort location
COGEGGMA_01061	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01062	6.38e-140	-	-	-	-	-	-	-	-
COGEGGMA_01063	8.63e-188	-	-	-	-	-	-	-	-
COGEGGMA_01064	1.57e-172	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
COGEGGMA_01065	7.78e-158	-	-	-	S	-	-	-	RloB-like protein
COGEGGMA_01066	0.0	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_01067	0.0	-	-	-	L	-	-	-	Recombinase
COGEGGMA_01068	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01069	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01070	1.71e-49	-	-	-	-	-	-	-	-
COGEGGMA_01071	1.59e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
COGEGGMA_01072	2.85e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_01073	7.69e-134	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01074	0.0	cspBA	-	-	O	-	-	-	Belongs to the peptidase S8 family
COGEGGMA_01075	1.71e-205	-	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_01076	7.72e-229	dsvA	-	-	C	-	-	-	Nitrite/Sulfite reductase ferredoxin-like half domain
COGEGGMA_01077	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01078	3.11e-67	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
COGEGGMA_01079	1.55e-179	-	-	-	-	-	-	-	-
COGEGGMA_01080	2.28e-114	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
COGEGGMA_01081	9e-275	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
COGEGGMA_01082	1.01e-148	-	-	-	L	ko:K07450	-	ko00000	protein MJ0014 - Methanococcus jannaschii gi 1590824 gb AAB97992.1 (U67460) conserved
COGEGGMA_01083	8.27e-105	-	-	-	S	ko:K06934	-	ko00000	Domain of unknown function (DUF296)
COGEGGMA_01084	7.34e-222	sorC	-	-	K	-	-	-	Putative sugar-binding domain
COGEGGMA_01085	3.17e-172	ulaF	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01086	3.98e-264	-	-	-	-	-	-	-	-
COGEGGMA_01087	0.0	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
COGEGGMA_01088	0.0	-	2.7.1.17, 2.7.1.30	-	G	ko:K00854,ko:K00864	ko00040,ko00561,ko01100,ko03320,ko04626,map00040,map00561,map01100,map03320,map04626	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_01089	2.15e-290	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
COGEGGMA_01090	2.34e-203	ulaE	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
COGEGGMA_01091	5.97e-92	-	-	-	-	-	-	-	-
COGEGGMA_01092	1.48e-175	gufA	-	-	P	ko:K07238	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01093	4.15e-94	-	-	-	S	-	-	-	CHY zinc finger
COGEGGMA_01094	7.83e-127	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
COGEGGMA_01095	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_01096	8.05e-252	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_01097	4.02e-134	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_01098	2.69e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01099	4.21e-212	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01100	1.73e-308	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_01101	1.32e-293	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
COGEGGMA_01102	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01103	3.98e-265	-	-	-	D	-	-	-	COG COG2184 Protein involved in cell division
COGEGGMA_01104	2.06e-193	-	-	-	H	-	-	-	SpoU rRNA Methylase family
COGEGGMA_01105	3.4e-295	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01106	0.0	gph	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
COGEGGMA_01107	7.66e-251	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COGEGGMA_01108	3.73e-263	-	-	-	GK	-	-	-	ROK family
COGEGGMA_01109	1.41e-301	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
COGEGGMA_01110	1.01e-32	-	-	-	-	-	-	-	-
COGEGGMA_01111	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
COGEGGMA_01112	2.33e-142	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COGEGGMA_01113	1.33e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
COGEGGMA_01114	1.94e-60	-	-	-	S	-	-	-	Nucleotidyltransferase domain
COGEGGMA_01115	1.1e-139	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COGEGGMA_01118	3.2e-95	-	-	-	-	-	-	-	-
COGEGGMA_01119	2.79e-224	-	-	-	T	-	-	-	Bacterial SH3 domain homologues
COGEGGMA_01120	1.95e-124	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_01121	6.6e-102	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_01122	4.71e-300	-	-	-	EG	-	-	-	GntP family permease
COGEGGMA_01123	0.0	-	-	-	V	-	-	-	Beta-lactamase
COGEGGMA_01124	8.75e-197	-	-	-	K	-	-	-	transcriptional regulator RpiR family
COGEGGMA_01125	8.17e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
COGEGGMA_01126	3.42e-41	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
COGEGGMA_01127	3.8e-251	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
COGEGGMA_01128	1.02e-280	csd	-	-	E	-	-	-	cysteine desulfurase family protein
COGEGGMA_01129	5.73e-208	cmpR	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_01130	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COGEGGMA_01131	4.48e-173	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
COGEGGMA_01132	1.06e-194	nodI	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_01133	5.04e-164	cobI	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01134	1.03e-118	-	-	-	P	-	-	-	abc-type fe3 -hydroxamate transport system, periplasmic component
COGEGGMA_01135	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
COGEGGMA_01136	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
COGEGGMA_01137	8.35e-176	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
COGEGGMA_01138	9.89e-172	-	-	-	K	ko:K02444	-	ko00000,ko03000	Transcriptional regulator, DeoR
COGEGGMA_01139	1.15e-236	-	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COGEGGMA_01140	2.42e-236	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COGEGGMA_01141	9.03e-185	-	-	-	EP	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COGEGGMA_01142	1.02e-205	-	-	-	P	ko:K13890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01143	0.0	-	-	-	E	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
COGEGGMA_01144	1.24e-196	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	Mechanosensitive ion channel
COGEGGMA_01145	2.02e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
COGEGGMA_01146	3.56e-47	-	-	-	G	-	-	-	phosphoenolpyruvate-dependent sugar phosphotransferase system
COGEGGMA_01147	2.01e-212	-	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_01148	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
COGEGGMA_01149	8.12e-300	-	-	-	S	-	-	-	Aminopeptidase
COGEGGMA_01150	5.06e-240	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
COGEGGMA_01151	1.63e-280	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COGEGGMA_01152	4.09e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01153	7.24e-102	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
COGEGGMA_01154	3.29e-234	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COGEGGMA_01155	5.49e-203	dapF_2	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COGEGGMA_01157	1.52e-206	-	-	-	K	-	-	-	PFAM AraC-like ligand binding domain
COGEGGMA_01158	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COGEGGMA_01159	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COGEGGMA_01160	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01161	6.26e-118	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COGEGGMA_01162	7.18e-185	hisA	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01163	2.27e-18	-	-	-	-	-	-	-	-
COGEGGMA_01164	5.62e-292	dacB2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_01165	1.49e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COGEGGMA_01166	1.25e-206	dapA	4.3.3.7	-	H	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COGEGGMA_01167	2.1e-109	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_01168	1.25e-148	ssb1	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01169	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA BipA homolog
COGEGGMA_01170	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01171	3.65e-256	-	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
COGEGGMA_01172	5.94e-305	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COGEGGMA_01173	7.62e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01174	1.92e-118	-	-	-	C	-	-	-	Flavodoxin domain
COGEGGMA_01175	1.87e-79	-	-	-	-	-	-	-	-
COGEGGMA_01176	3.13e-86	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COGEGGMA_01177	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase Rossmann domain
COGEGGMA_01178	2.38e-274	-	-	-	GK	-	-	-	ROK family
COGEGGMA_01179	0.0	bbmA	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
COGEGGMA_01180	1.64e-196	-	-	-	S	-	-	-	Fic/DOC family
COGEGGMA_01181	4.53e-236	-	-	-	L	-	-	-	Transposase, IS605 OrfB family
COGEGGMA_01182	3.76e-97	-	-	-	-	-	-	-	-
COGEGGMA_01183	2.08e-112	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01184	5.17e-180	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_01185	1.69e-313	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_01186	2.41e-315	-	-	-	L	-	-	-	Site-specific recombinase, phage integrase family
COGEGGMA_01187	9.41e-140	-	-	-	K	-	-	-	Helix-turn-helix domain
COGEGGMA_01188	5.51e-46	-	-	-	L	-	-	-	Excisionase from transposon Tn916
COGEGGMA_01189	1.99e-73	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01190	1.23e-67	-	-	-	-	-	-	-	-
COGEGGMA_01191	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01192	1.63e-159	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01193	5.34e-140	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
COGEGGMA_01194	9.8e-199	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
COGEGGMA_01195	1.68e-166	-	-	-	K	ko:K18349	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	Transcriptional regulatory protein, C terminal
COGEGGMA_01196	1.29e-106	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01197	1.87e-248	vanS	2.7.13.3	-	T	ko:K18350	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
COGEGGMA_01198	1.21e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_01199	1.03e-284	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_01200	1.56e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01201	3.06e-51	-	-	-	K	ko:K02099	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
COGEGGMA_01202	0.0	-	-	-	T	-	-	-	HAMP domain protein
COGEGGMA_01203	1.84e-302	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_01204	1.71e-206	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01205	1.14e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	abc transporter permease protein
COGEGGMA_01206	9.51e-295	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
COGEGGMA_01207	4.24e-310	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_01208	4.49e-232	-	-	-	K	-	-	-	AraC-like ligand binding domain
COGEGGMA_01209	0.0	malL_2	3.2.1.1, 3.2.1.10	GH13	G	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01210	2.48e-154	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
COGEGGMA_01211	1.13e-72	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
COGEGGMA_01212	0.0	malL	3.2.1.1, 3.2.1.10	GH13	G	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01213	6.16e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
COGEGGMA_01214	0.0	-	-	-	M	-	-	-	non supervised orthologous group
COGEGGMA_01215	8.89e-213	thyA	2.1.1.45	-	H	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COGEGGMA_01216	1.67e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COGEGGMA_01217	6.59e-256	ilvE	2.6.1.42, 4.1.3.38	-	EH	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
COGEGGMA_01218	4.74e-264	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01219	5.19e-254	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01220	6.51e-247	ispG	1.17.7.1, 1.17.7.3	-	H	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COGEGGMA_01221	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COGEGGMA_01222	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01224	0.0	purF_1	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_01225	1.8e-96	-	-	-	S	-	-	-	growth of symbiont in host cell
COGEGGMA_01226	1.52e-43	-	-	-	K	-	-	-	Helix-turn-helix domain
COGEGGMA_01227	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
COGEGGMA_01228	1.88e-221	dprA	-	-	L	ko:K04096	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01229	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COGEGGMA_01230	1.67e-177	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
COGEGGMA_01231	7.18e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COGEGGMA_01232	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COGEGGMA_01233	5.98e-111	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
COGEGGMA_01234	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
COGEGGMA_01235	1.08e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
COGEGGMA_01236	6.91e-174	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01237	1.13e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_01239	1.05e-46	-	-	-	-	-	-	-	-
COGEGGMA_01240	8.92e-271	-	-	-	S	-	-	-	3D domain
COGEGGMA_01241	9.73e-317	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01243	7.94e-293	-	-	-	C	ko:K19955	-	ko00000,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01244	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_01245	1.71e-210	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport systems
COGEGGMA_01246	2.91e-193	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01247	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_01248	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_01249	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Hydrolase Family 3
COGEGGMA_01250	1.11e-241	-	-	-	-	-	-	-	-
COGEGGMA_01251	3.7e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
COGEGGMA_01252	2.48e-193	-	-	-	K	-	-	-	FR47-like protein
COGEGGMA_01253	1.39e-166	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COGEGGMA_01254	1.97e-151	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
COGEGGMA_01255	3.21e-32	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGEGGMA_01256	1.16e-87	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COGEGGMA_01257	3.6e-112	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGEGGMA_01258	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COGEGGMA_01259	1.64e-206	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COGEGGMA_01260	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COGEGGMA_01261	6.42e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
COGEGGMA_01262	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
COGEGGMA_01263	1.28e-229	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	COG COG3049 Penicillin V acylase and related amidases
COGEGGMA_01264	4.43e-129	-	3.4.23.43	-	NOU	ko:K02278	-	ko00000,ko01000,ko02035,ko02044	Type IV leader peptidase family
COGEGGMA_01265	3.37e-249	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01266	1.33e-276	ptlH	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	flp pilus assembly ATPase CpaF
COGEGGMA_01267	8.28e-176	tadB	-	-	U	ko:K12510	-	ko00000,ko02044	Flp pilus assembly protein TadB
COGEGGMA_01268	4.49e-235	-	-	-	NU	ko:K12511	-	ko00000,ko02044	Type II secretion system
COGEGGMA_01269	1.49e-32	-	-	-	S	-	-	-	Putative Flagellin, Flp1-like, domain
COGEGGMA_01270	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01271	6.42e-200	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01272	2.16e-103	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
COGEGGMA_01273	2.15e-104	-	-	-	-	-	-	-	-
COGEGGMA_01274	0.0	-	-	-	T	-	-	-	Forkhead associated domain
COGEGGMA_01275	1.07e-134	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	PFAM Rhomboid family
COGEGGMA_01276	1.83e-164	-	-	-	H	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
COGEGGMA_01277	5.29e-95	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_01278	1.15e-122	-	-	-	K	-	-	-	Sigma-70 region 2
COGEGGMA_01279	5.23e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COGEGGMA_01280	9.21e-89	-	-	-	-	-	-	-	-
COGEGGMA_01281	0.0	-	-	-	J	ko:K07576	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01282	9.1e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01283	7.42e-162	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COGEGGMA_01284	5.84e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01285	1.45e-280	-	-	-	J	-	-	-	Methyltransferase domain
COGEGGMA_01286	0.0	GcvP	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01287	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01288	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
COGEGGMA_01289	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score 10.00
COGEGGMA_01290	1.51e-261	-	-	-	L	ko:K03547	-	ko00000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_01291	1.39e-297	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01292	2.46e-292	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
COGEGGMA_01293	5.45e-232	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
COGEGGMA_01294	6.4e-270	dnaD	-	-	L	-	-	-	DnaD domain protein
COGEGGMA_01295	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
COGEGGMA_01296	5.33e-304	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COGEGGMA_01297	9.02e-256	glgD	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01298	5.64e-59	spoVG	-	-	D	ko:K06412	-	ko00000	Could be involved in septation
COGEGGMA_01299	2.31e-185	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Psort location Extracellular, score
COGEGGMA_01300	1.2e-171	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01301	5.23e-256	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01303	1.68e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COGEGGMA_01304	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01305	9e-258	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COGEGGMA_01306	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COGEGGMA_01307	3.98e-72	-	-	-	L	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COGEGGMA_01308	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COGEGGMA_01309	1.56e-258	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
COGEGGMA_01310	8.69e-149	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COGEGGMA_01311	1.35e-201	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01312	7.95e-222	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01313	4.45e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF1256)
COGEGGMA_01314	9.31e-283	-	-	-	M	-	-	-	Lysin motif
COGEGGMA_01315	1.54e-278	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01316	1.04e-152	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01317	2.65e-87	-	-	-	L	-	-	-	Transposase
COGEGGMA_01318	3.62e-50	-	-	-	K	-	-	-	sequence-specific DNA binding
COGEGGMA_01319	9.24e-213	-	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
COGEGGMA_01320	7.6e-299	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_01321	4.75e-188	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01322	3.92e-144	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01323	1.4e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
COGEGGMA_01324	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
COGEGGMA_01325	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminal domain
COGEGGMA_01326	3.78e-57	-	-	-	-	-	-	-	-
COGEGGMA_01327	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
COGEGGMA_01328	1.1e-230	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_01329	4.39e-247	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
COGEGGMA_01330	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	family 43
COGEGGMA_01331	6.84e-225	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_01332	0.0	-	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_01333	1.03e-206	-	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01334	1.25e-203	-	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01335	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
COGEGGMA_01336	3.05e-196	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01337	7.73e-176	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COGEGGMA_01338	2.83e-261	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COGEGGMA_01339	1.68e-161	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
COGEGGMA_01341	6.61e-196	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
COGEGGMA_01342	2.25e-113	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
COGEGGMA_01343	1.01e-119	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
COGEGGMA_01344	6.23e-100	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COGEGGMA_01345	3.42e-133	-	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COGEGGMA_01346	2.97e-150	-	-	-	P	-	-	-	Belongs to the ABC transporter superfamily
COGEGGMA_01347	4.51e-24	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
COGEGGMA_01348	8.09e-168	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
COGEGGMA_01349	5.03e-136	-	-	-	G	-	-	-	beta-fructofuranosidase activity
COGEGGMA_01351	3.43e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
COGEGGMA_01353	2.6e-201	-	-	-	GK	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01354	1.24e-179	-	-	-	G	-	-	-	Phosphoglycerate mutase family
COGEGGMA_01355	8.94e-276	-	-	-	S	-	-	-	Psort location
COGEGGMA_01356	7.54e-40	-	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
COGEGGMA_01357	3.01e-179	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
COGEGGMA_01358	1.85e-303	thiH	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01359	5.91e-138	tenI	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
COGEGGMA_01360	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
COGEGGMA_01362	2.83e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01363	4.53e-199	alkA	4.2.99.18	-	L	ko:K03660	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	8-oxoguanine DNA glycosylase
COGEGGMA_01364	1.37e-64	-	-	-	-	-	-	-	-
COGEGGMA_01365	3.72e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COGEGGMA_01366	7.75e-300	-	-	-	-	-	-	-	-
COGEGGMA_01367	0.0	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COGEGGMA_01368	1.21e-212	-	-	-	K	-	-	-	Cupin domain
COGEGGMA_01369	8.93e-185	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_01370	7.83e-212	-	-	-	-	-	-	-	-
COGEGGMA_01371	5.04e-173	-	-	-	KT	-	-	-	LytTr DNA-binding domain
COGEGGMA_01372	0.0	-	-	-	-	-	-	-	-
COGEGGMA_01373	7.57e-63	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	ParE-like toxin of type II bacterial toxin-antitoxin system
COGEGGMA_01374	1.19e-80	-	-	-	K	-	-	-	toxin-antitoxin pair type II binding
COGEGGMA_01375	1.15e-233	-	-	-	S	-	-	-	Domain of unknown function, E. rectale Gene description (DUF3878)
COGEGGMA_01376	1.28e-184	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01377	4.22e-136	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
COGEGGMA_01378	1.25e-301	yqxK	3.6.4.12	-	-	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	-
COGEGGMA_01379	1.46e-108	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
COGEGGMA_01380	3.27e-116	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01381	1.28e-49	-	-	-	K	-	-	-	Protein of unknown function (DUF739)
COGEGGMA_01382	2.05e-28	-	-	-	-	-	-	-	-
COGEGGMA_01383	1.7e-59	-	-	-	S	-	-	-	Phage holin family Hol44, in holin superfamily V
COGEGGMA_01384	0.0	-	-	-	M	-	-	-	autolytic lysozime (1,4-beta-N-acetylmuramidase), family 25 of glycosyl hydrolases
COGEGGMA_01385	3.53e-17	cotJC	-	-	P	ko:K06334,ko:K07217	-	ko00000	catalase activity
COGEGGMA_01386	1.35e-64	cotJB	-	-	S	ko:K06333	-	ko00000	COG NOG18028 non supervised orthologous group
COGEGGMA_01387	1.14e-50	-	-	-	S	-	-	-	Spore coat associated protein JA (CotJA)
COGEGGMA_01388	2.34e-200	-	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metallo-beta-lactamase superfamily
COGEGGMA_01389	4.17e-157	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01390	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01391	7.59e-267	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
COGEGGMA_01392	2.64e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
COGEGGMA_01393	1.02e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COGEGGMA_01394	8.51e-214	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score 8.87
COGEGGMA_01395	5.81e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
COGEGGMA_01396	6.9e-298	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COGEGGMA_01397	4.68e-99	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COGEGGMA_01398	1.23e-96	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COGEGGMA_01399	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01400	0.0	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COGEGGMA_01401	0.0	gltX	6.1.1.17, 6.1.1.24	-	H	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COGEGGMA_01402	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	helicase
COGEGGMA_01403	2.8e-135	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01404	1.28e-265	-	-	-	S	-	-	-	amine dehydrogenase activity
COGEGGMA_01405	4.03e-240	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
COGEGGMA_01406	4.35e-120	-	-	-	S	ko:K06391	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01407	9.49e-35	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
COGEGGMA_01408	1.25e-80	spoIIIAD	-	-	S	ko:K06393	-	ko00000	COG NOG13205 non supervised orthologous group
COGEGGMA_01409	3.75e-269	spoIIIAE	-	-	S	ko:K06394	-	ko00000	Stage III sporulation protein
COGEGGMA_01410	1.59e-123	-	-	-	S	-	-	-	Stage III sporulation protein AF (Spore_III_AF)
COGEGGMA_01411	2.93e-64	spoIIIAG	-	-	S	ko:K06396	-	ko00000	COG NOG11553 non supervised orthologous group
COGEGGMA_01412	4.89e-160	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
COGEGGMA_01413	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COGEGGMA_01414	8.03e-79	asp	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01415	5.6e-73	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COGEGGMA_01416	1.49e-291	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COGEGGMA_01417	7.07e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COGEGGMA_01418	7.21e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COGEGGMA_01419	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COGEGGMA_01420	5.27e-194	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
COGEGGMA_01421	5.1e-205	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COGEGGMA_01422	6.17e-99	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
COGEGGMA_01423	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
COGEGGMA_01424	5.39e-292	spoIVB	3.4.21.116	-	T	ko:K06399	-	ko00000,ko01000,ko01002	stage IV sporulation protein B
COGEGGMA_01425	1.23e-187	spo0A	-	-	NT	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
COGEGGMA_01426	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
COGEGGMA_01427	3.38e-251	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COGEGGMA_01428	4.55e-131	recX	-	-	S	ko:K03565	-	ko00000,ko03400	RecX family
COGEGGMA_01429	2.79e-299	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
COGEGGMA_01430	1.72e-136	-	-	-	-	-	-	-	-
COGEGGMA_01431	7.57e-211	xerC	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COGEGGMA_01433	2.12e-253	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COGEGGMA_01434	2.46e-305	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
COGEGGMA_01435	1.09e-104	iscR	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01436	3.19e-283	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
COGEGGMA_01437	6.48e-104	nifU	-	-	C	ko:K04488	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01438	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
COGEGGMA_01439	0.0	ams	2.4.1.4, 3.2.1.1, 5.4.99.16	GH13	G	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
COGEGGMA_01440	6.36e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01441	2.56e-217	-	-	-	-	-	-	-	-
COGEGGMA_01442	3.71e-32	-	-	-	S	-	-	-	Helix-turn-helix domain
COGEGGMA_01443	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
COGEGGMA_01444	5.55e-54	-	-	-	-	-	-	-	-
COGEGGMA_01445	1.87e-217	-	-	-	S	-	-	-	Phage capsid family
COGEGGMA_01446	7.79e-44	-	-	-	S	-	-	-	Excisionase from transposon Tn916
COGEGGMA_01447	2.6e-42	-	-	-	-	-	-	-	-
COGEGGMA_01448	5.57e-307	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_01449	0.0	-	-	-	S	-	-	-	COG NOG11424 non supervised orthologous group
COGEGGMA_01450	6.87e-117	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COGEGGMA_01451	3.43e-234	-	-	-	-	-	-	-	-
COGEGGMA_01452	5.17e-178	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_01453	3.52e-201	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_01454	1.05e-225	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
COGEGGMA_01455	6.08e-156	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Psort location Cytoplasmic, score 8.87
COGEGGMA_01456	1.79e-144	-	-	-	S	-	-	-	DUF218 domain
COGEGGMA_01457	2.26e-286	-	-	-	S	ko:K03699	-	ko00000,ko02042	COG COG1253 Hemolysins and related proteins containing CBS domains
COGEGGMA_01458	3.75e-256	-	-	-	-	-	-	-	-
COGEGGMA_01459	5.93e-73	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01460	1.83e-20	scfA	-	-	S	-	-	-	Psort location Extracellular, score 8.82
COGEGGMA_01461	0.0	scfB	-	-	C	ko:K06871	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01462	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COGEGGMA_01463	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_01464	4.17e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COGEGGMA_01465	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COGEGGMA_01466	4.55e-156	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
COGEGGMA_01467	0.0	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
COGEGGMA_01468	8.1e-160	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01469	4.11e-293	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
COGEGGMA_01470	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COGEGGMA_01471	4.97e-170	yfcA	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
COGEGGMA_01472	3.13e-274	-	-	-	M	-	-	-	cell wall binding repeat
COGEGGMA_01473	9.91e-307	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
COGEGGMA_01474	7.73e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_01475	0.0	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COGEGGMA_01476	1.88e-290	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01477	2.97e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
COGEGGMA_01478	0.0	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COGEGGMA_01479	7.78e-202	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
COGEGGMA_01480	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Psort location Cytoplasmic, score 9.98
COGEGGMA_01481	1.52e-300	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
COGEGGMA_01482	7.74e-121	-	-	-	-	-	-	-	-
COGEGGMA_01483	2.71e-151	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01484	6.27e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01485	2.96e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01486	2.76e-216	ytrB	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_01487	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_01488	9.67e-174	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate
COGEGGMA_01489	7.11e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
COGEGGMA_01490	1.02e-192	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COGEGGMA_01491	2.16e-123	-	-	-	-	-	-	-	-
COGEGGMA_01492	0.0	-	-	-	S	-	-	-	regulation of response to stimulus
COGEGGMA_01493	1.47e-60	-	-	-	L	-	-	-	transposase activity
COGEGGMA_01494	0.0	-	4.2.2.5	PL8	N	ko:K19049	-	ko00000,ko01000	domain, Protein
COGEGGMA_01495	1.92e-37	-	-	-	S	-	-	-	cell adhesion involved in biofilm formation
COGEGGMA_01496	0.0	-	-	-	-	-	-	-	-
COGEGGMA_01497	6.65e-217	-	-	-	S	-	-	-	regulation of response to stimulus
COGEGGMA_01498	7.07e-97	hgdC	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
COGEGGMA_01499	4.82e-228	-	-	-	S	-	-	-	domain protein
COGEGGMA_01500	9.68e-36	-	-	-	S	-	-	-	COG NOG17864 non supervised orthologous group
COGEGGMA_01501	6.14e-39	pspC	-	-	KT	-	-	-	PspC domain
COGEGGMA_01502	1.43e-147	-	-	-	-	-	-	-	-
COGEGGMA_01503	1.35e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01504	2.25e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01505	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
COGEGGMA_01506	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
COGEGGMA_01507	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_01508	1.48e-89	-	-	-	S	-	-	-	FMN-binding domain protein
COGEGGMA_01509	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COGEGGMA_01510	1.35e-203	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COGEGGMA_01511	5.29e-199	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01512	2.6e-195	-	-	-	-	-	-	-	-
COGEGGMA_01513	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_01514	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_01515	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_01516	7.17e-104	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01517	1.1e-209	-	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_01518	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COGEGGMA_01519	7.25e-240	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01520	0.0	-	-	-	P	-	-	-	Putative citrate transport
COGEGGMA_01521	1.44e-35	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
COGEGGMA_01522	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COGEGGMA_01523	3.72e-135	-	-	-	L	-	-	-	Reverse transcriptase
COGEGGMA_01524	6.99e-307	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_01525	6e-245	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_01526	8.24e-248	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
COGEGGMA_01527	8.77e-140	-	-	-	L	-	-	-	Reverse transcriptase
COGEGGMA_01528	1.07e-120	-	-	-	C	-	-	-	Nitroreductase family
COGEGGMA_01529	8.76e-73	hxlR	-	-	K	-	-	-	HxlR-like helix-turn-helix
COGEGGMA_01531	1.7e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01532	5.13e-55	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01533	1.29e-258	xerS	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01534	1.56e-98	FcbC	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
COGEGGMA_01535	6.06e-234	-	-	-	D	-	-	-	Peptidase family M23
COGEGGMA_01536	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01537	1.58e-153	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG14451 non supervised orthologous group
COGEGGMA_01538	1.67e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COGEGGMA_01539	3.57e-120	lspA	3.4.23.36	-	M	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COGEGGMA_01540	5.93e-261	aroB	2.7.1.71, 4.2.3.4	-	E	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COGEGGMA_01541	1.83e-180	-	-	-	S	-	-	-	S4 domain protein
COGEGGMA_01542	2.07e-109	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COGEGGMA_01543	1.14e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COGEGGMA_01544	0.0	-	-	-	-	-	-	-	-
COGEGGMA_01545	4.19e-146	lexA	3.4.21.88	-	L	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COGEGGMA_01546	1.23e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COGEGGMA_01547	3.1e-143	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01548	3.59e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COGEGGMA_01549	6e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
COGEGGMA_01550	1.16e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COGEGGMA_01551	3.52e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
COGEGGMA_01552	1.58e-70	-	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
COGEGGMA_01553	3.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
COGEGGMA_01554	9.24e-288	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	TIGRFAM ribonuclease, Rne Rng family
COGEGGMA_01555	4.13e-165	-	-	-	S	-	-	-	Radical SAM-linked protein
COGEGGMA_01556	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
COGEGGMA_01557	0.0	-	-	-	L	-	-	-	Uncharacterized conserved protein (DUF2075)
COGEGGMA_01558	3.2e-83	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
COGEGGMA_01559	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
COGEGGMA_01560	1.12e-55	-	-	-	-	-	-	-	-
COGEGGMA_01561	2.06e-258	-	-	-	J	ko:K02238	-	ko00000,ko00002,ko02044	Metallo-beta-lactamase domain protein
COGEGGMA_01562	7.15e-122	yciA	-	-	I	-	-	-	Thioesterase superfamily
COGEGGMA_01563	0.0	gltA	2.3.3.1	-	H	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
COGEGGMA_01564	0.0	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding
COGEGGMA_01565	3.51e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COGEGGMA_01566	1.99e-226	-	-	-	KT	-	-	-	BlaR1 peptidase M56
COGEGGMA_01567	2.13e-83	-	-	-	-	-	-	-	-
COGEGGMA_01568	1.35e-55	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
COGEGGMA_01569	8.09e-266	-	-	-	S	-	-	-	FMN_bind
COGEGGMA_01570	0.0	-	-	-	N	-	-	-	domain, Protein
COGEGGMA_01571	2.75e-245	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COGEGGMA_01572	1.4e-188	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01573	7e-93	-	-	-	S	-	-	-	FMN_bind
COGEGGMA_01574	6.81e-239	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
COGEGGMA_01575	1.07e-150	-	-	-	S	-	-	-	YheO-like PAS domain
COGEGGMA_01576	2.07e-300	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_01577	3.98e-169	-	-	-	T	-	-	-	LytTr DNA-binding domain protein
COGEGGMA_01578	5.14e-42	-	-	-	-	-	-	-	-
COGEGGMA_01579	2.32e-121	-	-	-	-	-	-	-	-
COGEGGMA_01580	9.63e-248	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COGEGGMA_01581	5.14e-111	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01582	4.65e-256	-	-	-	T	-	-	-	Tyrosine phosphatase family
COGEGGMA_01583	7.01e-217	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
COGEGGMA_01584	1.25e-201	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
COGEGGMA_01585	7.04e-308	apeB	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
COGEGGMA_01586	1.45e-76	-	-	-	S	-	-	-	Cupin domain
COGEGGMA_01587	1.16e-204	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COGEGGMA_01588	7.48e-194	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COGEGGMA_01589	2.02e-117	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COGEGGMA_01590	5e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase I
COGEGGMA_01591	7.01e-239	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
COGEGGMA_01592	8.79e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01593	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	COG COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair
COGEGGMA_01594	9.49e-98	-	-	-	S	-	-	-	Uncharacterized BCR, YaiI/YqxD family COG1671
COGEGGMA_01595	3.92e-83	-	-	-	E	-	-	-	Glyoxalase-like domain
COGEGGMA_01596	1.16e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
COGEGGMA_01597	1.51e-47	-	-	-	-	-	-	-	-
COGEGGMA_01599	1.12e-64	-	-	-	-	-	-	-	-
COGEGGMA_01600	4.21e-91	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	low molecular weight
COGEGGMA_01601	4.05e-305	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
COGEGGMA_01602	2.12e-66	-	-	-	L	-	-	-	Transposase IS200 like
COGEGGMA_01604	5.34e-305	-	-	-	L	-	-	-	PFAM transposase IS66
COGEGGMA_01605	1.51e-80	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
COGEGGMA_01606	0.000207	-	-	-	L	-	-	-	transposase activity
COGEGGMA_01608	3.08e-27	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
COGEGGMA_01609	1.8e-112	-	-	-	O	-	-	-	Belongs to the peptidase S8 family
COGEGGMA_01610	1.24e-08	-	-	-	J	-	-	-	Histone methylation protein DOT1
COGEGGMA_01611	1.07e-99	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COGEGGMA_01612	9.96e-85	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COGEGGMA_01614	6.62e-62	-	-	-	C	-	-	-	4Fe-4S single cluster domain
COGEGGMA_01618	1.69e-33	-	-	-	L	-	-	-	Transposase
COGEGGMA_01619	4e-13	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family
COGEGGMA_01620	5.18e-133	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.98
COGEGGMA_01621	1.35e-56	-	-	-	-	-	-	-	-
COGEGGMA_01622	3.78e-306	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_01623	6.55e-251	-	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
COGEGGMA_01624	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
COGEGGMA_01625	6.37e-20	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
COGEGGMA_01626	0.0	-	-	-	S	-	-	-	PD-(D/E)XK nuclease superfamily
COGEGGMA_01627	1.37e-179	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
COGEGGMA_01628	2.66e-85	-	-	-	S	-	-	-	Hemerythrin HHE cation binding domain protein
COGEGGMA_01629	1.52e-109	-	-	-	-	-	-	-	-
COGEGGMA_01631	6.85e-142	sidE	-	-	D	ko:K10110,ko:K15473	ko02010,ko05134,map02010,map05134	ko00000,ko00001,ko00002,ko02000	nuclear chromosome segregation
COGEGGMA_01633	5.09e-78	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
COGEGGMA_01634	0.0	-	-	-	L	-	-	-	helicase
COGEGGMA_01635	1.57e-116	-	-	-	H	-	-	-	Tellurite resistance protein TehB
COGEGGMA_01636	2.01e-141	-	-	-	S	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
COGEGGMA_01637	1.84e-117	-	-	-	Q	-	-	-	Isochorismatase family
COGEGGMA_01638	4.03e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
COGEGGMA_01639	1.35e-119	-	-	-	-	-	-	-	-
COGEGGMA_01640	1.59e-241	-	-	-	S	-	-	-	AAA ATPase domain
COGEGGMA_01641	1.21e-75	-	-	-	P	-	-	-	Belongs to the ArsC family
COGEGGMA_01642	9.63e-153	-	-	-	-	-	-	-	-
COGEGGMA_01643	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
COGEGGMA_01644	2.11e-221	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COGEGGMA_01645	1.61e-251	-	-	-	J	-	-	-	RNA pseudouridylate synthase
COGEGGMA_01646	2.6e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COGEGGMA_01647	9.66e-292	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COGEGGMA_01648	2.23e-150	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01649	2.86e-262	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COGEGGMA_01650	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	AAA domain (dynein-related subfamily)
COGEGGMA_01651	1.83e-259	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
COGEGGMA_01652	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
COGEGGMA_01653	6.22e-207	-	-	-	K	-	-	-	transcriptional regulator AraC family
COGEGGMA_01654	1.7e-306	fliU	-	-	S	ko:K18475	-	ko00000,ko01000,ko02035	N-methylation of lysine residues in flagellin
COGEGGMA_01655	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
COGEGGMA_01656	8.11e-179	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01657	1.06e-99	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_01658	6.96e-116	XK26_06155	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01659	0.0	-	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
COGEGGMA_01660	0.0	-	2.1.1.72	-	L	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA methylase
COGEGGMA_01661	1.35e-46	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_01662	0.0	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
COGEGGMA_01663	0.0	-	-	-	S	-	-	-	nucleotidyltransferase activity
COGEGGMA_01664	0.0	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
COGEGGMA_01665	2.68e-67	-	-	-	-	-	-	-	-
COGEGGMA_01666	1.98e-258	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01667	5.26e-20	-	-	-	-	-	-	-	-
COGEGGMA_01668	0.0	-	-	-	M	-	-	-	Psort location Cellwall, score
COGEGGMA_01669	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
COGEGGMA_01670	1.13e-294	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
COGEGGMA_01671	5.47e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4315)
COGEGGMA_01672	0.0	-	-	-	M	-	-	-	NlpC/P60 family
COGEGGMA_01674	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01675	2.89e-192	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01676	0.0	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
COGEGGMA_01677	6.56e-40	-	-	-	-	-	-	-	-
COGEGGMA_01678	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01679	1.2e-150	-	-	-	L	-	-	-	CHC2 zinc finger domain protein
COGEGGMA_01680	0.0	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01681	2.3e-124	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01682	9.43e-127	noxC	-	-	C	-	-	-	Nitroreductase family
COGEGGMA_01683	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
COGEGGMA_01684	2.85e-207	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
COGEGGMA_01686	0.0	tvaI	-	-	G	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_01687	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COGEGGMA_01688	3.04e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COGEGGMA_01689	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COGEGGMA_01690	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
COGEGGMA_01691	2.36e-47	-	-	-	D	-	-	-	Septum formation initiator
COGEGGMA_01692	2.05e-102	-	-	-	S	-	-	-	Spore cortex protein YabQ (Spore_YabQ)
COGEGGMA_01693	8.11e-58	yabP	-	-	S	-	-	-	Sporulation protein YabP
COGEGGMA_01694	3.38e-46	hslR	-	-	J	-	-	-	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
COGEGGMA_01695	1.6e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COGEGGMA_01696	2.61e-241	cotS	-	-	S	ko:K06331,ko:K06337	-	ko00000	Spore coat protein, CotS family
COGEGGMA_01697	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
COGEGGMA_01698	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
COGEGGMA_01699	3.12e-120	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
COGEGGMA_01700	9.72e-103	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01701	5.35e-246	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COGEGGMA_01702	1.41e-265	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
COGEGGMA_01703	0.0	-	-	-	S	-	-	-	Uncharacterized membrane protein (DUF2298)
COGEGGMA_01704	0.0	-	-	-	M	-	-	-	chaperone-mediated protein folding
COGEGGMA_01705	1.81e-157	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
COGEGGMA_01706	0.0	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
COGEGGMA_01707	1.72e-40	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01708	3.26e-173	mecB	-	-	NOT	ko:K16511	-	ko00000	Negative regulator of genetic competence
COGEGGMA_01709	1.42e-39	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01710	1.17e-221	tsgC13	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COGEGGMA_01711	7.71e-255	tsgB13	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_01712	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	transport systems ATPase components
COGEGGMA_01713	1.21e-286	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
COGEGGMA_01714	3.78e-20	-	-	-	C	-	-	-	4Fe-4S binding domain
COGEGGMA_01715	1.44e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COGEGGMA_01716	2.12e-310	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
COGEGGMA_01717	2.09e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COGEGGMA_01718	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
COGEGGMA_01719	3.05e-57	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COGEGGMA_01720	3.43e-101	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COGEGGMA_01721	1.39e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
COGEGGMA_01722	1.4e-40	-	-	-	S	-	-	-	protein conserved in bacteria
COGEGGMA_01723	9.45e-178	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
COGEGGMA_01724	5.29e-199	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
COGEGGMA_01726	0.0	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
COGEGGMA_01727	8.58e-313	-	-	-	S	-	-	-	Putative metallopeptidase domain
COGEGGMA_01728	8.7e-65	-	-	-	-	-	-	-	-
COGEGGMA_01729	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COGEGGMA_01730	5.09e-304	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
COGEGGMA_01731	1.36e-303	xanP	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01732	0.0	-	-	-	O	-	-	-	Subtilase family
COGEGGMA_01733	1.3e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Prolipoprotein diacylglyceryl transferase
COGEGGMA_01734	9.95e-208	-	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
COGEGGMA_01735	1.54e-190	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
COGEGGMA_01736	1.75e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COGEGGMA_01737	1.41e-120	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
COGEGGMA_01738	0.0	algI	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_01739	4.91e-284	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
COGEGGMA_01740	4.31e-172	-	-	-	KT	-	-	-	LytTr DNA-binding domain
COGEGGMA_01741	2.33e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01742	4.12e-139	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
COGEGGMA_01743	5.03e-297	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01744	2.93e-125	-	-	-	-	-	-	-	-
COGEGGMA_01745	4.36e-15	-	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COGEGGMA_01746	1.91e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
COGEGGMA_01748	2.58e-87	-	-	-	K	-	-	-	Protein of unknown function (DUF3788)
COGEGGMA_01749	2.69e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
COGEGGMA_01750	2.94e-79	-	-	-	-	-	-	-	-
COGEGGMA_01751	8.16e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01752	0.0	lanM	-	-	V	-	-	-	Lanthionine synthetase C-like protein
COGEGGMA_01753	3.29e-32	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
COGEGGMA_01754	8.05e-118	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01755	2.45e-154	-	-	-	-	-	-	-	-
COGEGGMA_01756	1.08e-270	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01757	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
COGEGGMA_01758	2.75e-216	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
COGEGGMA_01759	8.21e-239	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COGEGGMA_01762	4.47e-85	-	-	-	C	ko:K06871	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01763	5.48e-101	-	-	-	C	-	-	-	4Fe-4S single cluster domain
COGEGGMA_01764	4.69e-86	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01765	4.46e-165	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01766	1.71e-193	-	-	-	-	-	-	-	-
COGEGGMA_01767	0.0	-	-	-	M	-	-	-	Papain-like cysteine protease AvrRpt2
COGEGGMA_01768	1.48e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF5038)
COGEGGMA_01769	0.0	-	-	-	U	-	-	-	AAA-like domain
COGEGGMA_01770	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
COGEGGMA_01771	2.12e-58	-	-	-	-	-	-	-	-
COGEGGMA_01772	3.19e-100	-	-	-	S	-	-	-	zinc-finger-containing domain
COGEGGMA_01773	7.65e-136	-	-	-	K	-	-	-	Sigma-70 region 2
COGEGGMA_01774	1.06e-159	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01775	3.36e-100	-	-	-	-	-	-	-	-
COGEGGMA_01776	5.94e-194	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_01777	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
COGEGGMA_01778	4.78e-312	-	-	-	C	ko:K06871	-	ko00000	Radical SAM domain protein
COGEGGMA_01780	2.21e-186	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
COGEGGMA_01781	8.58e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_01782	1.27e-158	-	-	-	T	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COGEGGMA_01783	1.62e-35	-	-	-	-	-	-	-	-
COGEGGMA_01784	5.92e-150	-	-	-	L	-	-	-	Single-strand binding protein family
COGEGGMA_01785	2.8e-185	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01786	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01787	0.0	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01788	2.31e-176	-	-	-	-	-	-	-	-
COGEGGMA_01789	3.67e-126	-	-	-	K	-	-	-	MraZ protein, putative antitoxin-like
COGEGGMA_01790	1.25e-265	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
COGEGGMA_01791	1.86e-48	-	-	-	-	-	-	-	-
COGEGGMA_01792	5.81e-125	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01793	2.83e-100	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
COGEGGMA_01794	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COGEGGMA_01795	4.88e-96	-	-	-	-	-	-	-	-
COGEGGMA_01796	4.75e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
COGEGGMA_01797	3.71e-53	-	-	-	-	-	-	-	-
COGEGGMA_01798	1.07e-113	-	-	-	O	ko:K09935	-	ko00000	Domain of unknown function (DUF1768)
COGEGGMA_01799	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
COGEGGMA_01800	1.92e-190	-	-	-	-	-	-	-	-
COGEGGMA_01801	1.06e-184	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
COGEGGMA_01802	1.48e-146	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01803	3.93e-290	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
COGEGGMA_01805	3.09e-149	-	-	-	-	-	-	-	-
COGEGGMA_01806	8.55e-64	-	-	-	-	-	-	-	-
COGEGGMA_01807	4.08e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF5348)
COGEGGMA_01808	1.56e-147	-	-	-	L	-	-	-	Resolvase, N terminal domain
COGEGGMA_01809	1.8e-91	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_01810	4.04e-240	-	-	-	S	-	-	-	alpha/beta hydrolase fold
COGEGGMA_01811	9.81e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	S-adenosylmethionine synthetase, C-terminal domain
COGEGGMA_01813	4.05e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_01814	2.67e-40	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01818	6.9e-217	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01819	8.89e-115	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_01823	1.49e-273	-	-	-	C	-	-	-	4Fe-4S single cluster domain
COGEGGMA_01824	1.04e-268	-	-	-	C	ko:K06871	-	ko00000	Radical SAM superfamily
COGEGGMA_01825	8.33e-215	-	-	-	O	-	-	-	Subtilase family
COGEGGMA_01826	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
COGEGGMA_01827	2.37e-291	-	-	-	C	ko:K06871	-	ko00000	4Fe-4S single cluster domain
COGEGGMA_01828	1.18e-194	-	-	-	M	-	-	-	Zinc dependent phospholipase C
COGEGGMA_01829	3.49e-267	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01830	1.49e-163	-	-	-	K	-	-	-	LytTr DNA-binding domain
COGEGGMA_01831	8.22e-54	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_01832	1.59e-227	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01833	1.58e-23	-	-	-	-	-	-	-	-
COGEGGMA_01834	1.12e-162	-	-	-	KT	-	-	-	phosphorelay signal transduction system
COGEGGMA_01835	8.28e-14	-	-	-	-	-	-	-	-
COGEGGMA_01836	2.41e-111	-	-	-	-	-	-	-	-
COGEGGMA_01837	1.17e-149	-	-	-	S	ko:K06889	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01838	1.26e-88	-	-	-	-	-	-	-	-
COGEGGMA_01839	5.01e-294	-	-	-	G	-	-	-	Major Facilitator
COGEGGMA_01840	8.62e-222	-	-	-	K	-	-	-	Cupin domain
COGEGGMA_01841	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
COGEGGMA_01842	2.63e-155	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01843	1.56e-162	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
COGEGGMA_01844	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_01845	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_01846	7.03e-246	-	-	-	S	-	-	-	Nitronate monooxygenase
COGEGGMA_01847	4.8e-308	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01848	4.74e-176	-	-	-	M	-	-	-	Transglutaminase-like superfamily
COGEGGMA_01849	0.0	Rnd	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01850	7.33e-311	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01851	1.3e-171	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01852	4.74e-191	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	cystine-binding periplasmic protein precursor
COGEGGMA_01853	8.52e-135	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01854	2.04e-157	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_01855	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01856	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COGEGGMA_01857	1.35e-199	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
COGEGGMA_01858	1.52e-124	secA_2	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01859	3.28e-122	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01860	8.31e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COGEGGMA_01861	4.58e-204	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
COGEGGMA_01862	5.6e-159	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COGEGGMA_01863	1.85e-266	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	pyruvate formate lyase activating
COGEGGMA_01864	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01865	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01866	7.17e-114	cotJC	-	-	P	ko:K06334	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01867	0.0	-	-	-	L	ko:K06400	-	ko00000	Resolvase, N terminal domain
COGEGGMA_01868	2.92e-131	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_01869	6.65e-196	-	-	-	-	-	-	-	-
COGEGGMA_01870	1.62e-100	-	-	-	E	-	-	-	Zn peptidase
COGEGGMA_01871	2.73e-50	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01872	2.84e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4258)
COGEGGMA_01873	5.35e-113	-	2.6.1.2, 2.6.1.66	-	K	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	sequence-specific DNA binding
COGEGGMA_01874	0.0	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase uridine kinase family
COGEGGMA_01875	5.46e-187	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
COGEGGMA_01876	2.91e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.87
COGEGGMA_01877	2.44e-234	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COGEGGMA_01878	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COGEGGMA_01879	1.99e-238	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
COGEGGMA_01881	1.22e-308	sleC	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01882	0.0	-	-	-	S	-	-	-	COG NOG08812 non supervised orthologous group
COGEGGMA_01883	2.56e-152	-	-	-	-	-	-	-	-
COGEGGMA_01884	5.38e-165	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
COGEGGMA_01885	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
COGEGGMA_01886	1.07e-302	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
COGEGGMA_01887	9.65e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COGEGGMA_01888	7.04e-176	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_01889	1.9e-170	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COGEGGMA_01890	1.12e-116	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COGEGGMA_01891	1.62e-160	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
COGEGGMA_01892	2.97e-176	-	-	-	-	-	-	-	-
COGEGGMA_01893	1.59e-136	-	-	-	F	-	-	-	Cytidylate kinase-like family
COGEGGMA_01894	1.34e-104	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COGEGGMA_01895	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COGEGGMA_01896	1.24e-43	-	-	-	U	-	-	-	Preprotein translocase SecG subunit
COGEGGMA_01897	4.64e-186	eno	4.2.1.11	-	H	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COGEGGMA_01898	0.0	-	-	-	L	-	-	-	Resolvase, N terminal domain
COGEGGMA_01899	0.0	-	-	-	L	-	-	-	Resolvase, N terminal domain
COGEGGMA_01900	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01902	7.06e-81	-	-	-	L	-	-	-	Toxic component of a toxin-antitoxin (TA) module
COGEGGMA_01903	5.23e-107	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01904	3.04e-36	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	regulation of RNA biosynthetic process
COGEGGMA_01905	3.87e-169	-	-	-	S	-	-	-	Putative esterase
COGEGGMA_01906	0.0	-	-	-	Q	-	-	-	AMP-binding enzyme C-terminal domain
COGEGGMA_01907	2.6e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COGEGGMA_01908	8.12e-91	-	-	-	S	-	-	-	YjbR
COGEGGMA_01909	0.0	-	-	-	L	-	-	-	Resolvase, N terminal domain
COGEGGMA_01910	3.34e-270	-	-	-	S	-	-	-	RES domain
COGEGGMA_01911	4.94e-226	-	-	-	-	-	-	-	-
COGEGGMA_01912	8.45e-204	-	-	-	-	-	-	-	-
COGEGGMA_01913	3.52e-32	-	-	-	-	-	-	-	-
COGEGGMA_01914	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01915	1.95e-158	-	-	-	H	-	-	-	CHC2 zinc finger
COGEGGMA_01916	2.39e-294	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
COGEGGMA_01917	1.42e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01918	9.41e-33	-	-	-	-	-	-	-	-
COGEGGMA_01919	2.18e-188	-	-	-	-	-	-	-	-
COGEGGMA_01920	6.56e-92	-	-	-	KT	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COGEGGMA_01921	0.0	-	-	-	KT	-	-	-	Peptidase, M56
COGEGGMA_01922	1.6e-82	-	-	-	K	-	-	-	Penicillinase repressor
COGEGGMA_01923	1.16e-81	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_01924	2.98e-270	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
COGEGGMA_01925	2.9e-143	-	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
COGEGGMA_01926	9.68e-31	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
COGEGGMA_01927	4.47e-34	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family
COGEGGMA_01928	3.63e-272	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	COG COG1454 Alcohol dehydrogenase, class IV
COGEGGMA_01929	2.02e-137	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_01930	1.29e-112	-	-	-	S	-	-	-	Predicted metal-binding protein (DUF2284)
COGEGGMA_01931	6.51e-224	-	-	-	E	-	-	-	Oligopeptide/dipeptide transporter, C-terminal region
COGEGGMA_01932	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
COGEGGMA_01933	6.09e-46	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01934	6.48e-84	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_01935	6.38e-181	-	-	-	P	-	-	-	VTC domain
COGEGGMA_01936	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
COGEGGMA_01937	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
COGEGGMA_01938	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
COGEGGMA_01939	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
COGEGGMA_01940	4.17e-205	-	-	-	-	-	-	-	-
COGEGGMA_01941	0.0	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Domain of unknown function (DUF4118)
COGEGGMA_01942	0.0	-	-	-	S	-	-	-	PA domain
COGEGGMA_01943	9.53e-160	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COGEGGMA_01944	6.46e-83	-	-	-	K	-	-	-	repressor
COGEGGMA_01945	8.12e-69	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
COGEGGMA_01946	4.35e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
COGEGGMA_01947	9.45e-152	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COGEGGMA_01948	1.37e-87	-	-	-	-	-	-	-	-
COGEGGMA_01949	6.48e-306	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
COGEGGMA_01950	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
COGEGGMA_01951	3.09e-66	-	-	-	S	-	-	-	NAD(P)H dehydrogenase (quinone) activity
COGEGGMA_01952	5.5e-165	-	-	-	S	-	-	-	YibE/F-like protein
COGEGGMA_01953	3.81e-254	-	-	-	S	-	-	-	PFAM YibE F family protein
COGEGGMA_01954	6.48e-244	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGEGGMA_01955	2.41e-142	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COGEGGMA_01956	2.33e-303	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_01957	8.4e-150	yrrM	-	-	S	-	-	-	O-methyltransferase
COGEGGMA_01958	1.86e-89	-	-	-	S	ko:K07082	-	ko00000	YceG-like family
COGEGGMA_01959	1.53e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01960	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COGEGGMA_01961	9.67e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_01962	5.45e-94	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COGEGGMA_01963	2.28e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
COGEGGMA_01964	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
COGEGGMA_01965	1.61e-48	-	-	-	G	-	-	-	PTS HPr component phosphorylation site
COGEGGMA_01966	7.55e-286	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COGEGGMA_01967	7.12e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
COGEGGMA_01968	4.44e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COGEGGMA_01969	3.51e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
COGEGGMA_01970	1.51e-177	-	-	-	I	-	-	-	PAP2 superfamily
COGEGGMA_01971	5.15e-269	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COGEGGMA_01972	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
COGEGGMA_01973	8.91e-136	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COGEGGMA_01974	3.16e-236	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COGEGGMA_01975	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COGEGGMA_01976	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_01977	7.83e-153	ttdB	4.2.1.2, 4.2.1.32	-	C	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Fumarase C-terminus
COGEGGMA_01978	1.01e-223	-	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
COGEGGMA_01979	7.17e-280	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
COGEGGMA_01980	1.31e-214	-	-	-	K	-	-	-	LysR substrate binding domain
COGEGGMA_01981	2.81e-73	-	-	-	N	-	-	-	domain, Protein
COGEGGMA_01982	8.67e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
COGEGGMA_01983	1.17e-25	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
COGEGGMA_01984	7.34e-291	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_01985	9.77e-34	-	-	-	-	-	-	-	-
COGEGGMA_01986	2.61e-303	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
COGEGGMA_01987	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COGEGGMA_01988	0.0	gatA	6.3.5.6, 6.3.5.7	-	H	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COGEGGMA_01989	3.23e-59	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COGEGGMA_01990	0.0	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COGEGGMA_01991	1.32e-120	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR
COGEGGMA_01992	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score 9.98
COGEGGMA_01993	1.38e-82	-	-	-	S	ko:K18843	-	ko00000,ko02048	HicB family
COGEGGMA_01994	8.86e-56	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
COGEGGMA_01995	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	NADH-dependent glutamate synthase small subunit
COGEGGMA_01996	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
COGEGGMA_01997	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COGEGGMA_01998	2.26e-46	-	-	-	G	-	-	-	phosphocarrier protein HPr
COGEGGMA_01999	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COGEGGMA_02000	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
COGEGGMA_02001	0.0	-	-	-	P	ko:K03320	-	ko00000,ko02000	COG COG0004 Ammonia permease
COGEGGMA_02002	1.33e-27	-	-	-	-	-	-	-	-
COGEGGMA_02004	1.4e-69	-	-	-	S	-	-	-	Bacterial SH3 domain homologues
COGEGGMA_02005	1.1e-80	-	-	-	-	-	-	-	-
COGEGGMA_02006	2.38e-109	-	-	-	KOT	-	-	-	Accessory gene regulator B
COGEGGMA_02007	7.08e-26	-	-	-	-	-	-	-	-
COGEGGMA_02008	8.69e-167	-	-	-	KT	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
COGEGGMA_02009	1.11e-300	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_02010	4.13e-104	-	-	-	S	-	-	-	Flavin reductase like domain
COGEGGMA_02011	3.54e-148	yicG	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02012	1.39e-296	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
COGEGGMA_02013	2.16e-98	-	-	-	L	-	-	-	Transposase IS200 like
COGEGGMA_02016	5.84e-87	-	-	-	L	-	-	-	Transposase
COGEGGMA_02017	6.61e-31	-	-	-	-	-	-	-	-
COGEGGMA_02018	2.11e-66	-	-	-	L	-	-	-	HNH endonuclease
COGEGGMA_02020	4.93e-69	-	-	-	-	-	-	-	-
COGEGGMA_02021	2.84e-33	-	-	-	-	-	-	-	-
COGEGGMA_02022	2.46e-67	-	-	-	S	ko:K19048	-	ko00000,ko02048	Toxin SymE, type I toxin-antitoxin system
COGEGGMA_02023	2.04e-17	-	-	-	S	-	-	-	Helix-turn-helix domain
COGEGGMA_02024	1.14e-102	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_02026	4.42e-234	-	-	-	-	-	-	-	-
COGEGGMA_02027	6.7e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02028	1.34e-200	-	-	-	-	-	-	-	-
COGEGGMA_02029	3.89e-179	-	-	-	-	-	-	-	-
COGEGGMA_02031	2.43e-235	-	-	-	-	-	-	-	-
COGEGGMA_02032	2.12e-205	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_02033	5.21e-101	-	-	-	KT	-	-	-	LytTr DNA-binding domain protein
COGEGGMA_02034	4.41e-31	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_02035	9.14e-79	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
COGEGGMA_02036	7.81e-162	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02037	1.8e-142	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02038	3.82e-185	-	-	-	D	-	-	-	PD-(D/E)XK nuclease family transposase
COGEGGMA_02039	6e-28	-	-	-	-	-	-	-	-
COGEGGMA_02040	3.11e-15	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02041	8.83e-208	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_02042	1.45e-152	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02043	2.96e-246	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02044	6.88e-277	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
COGEGGMA_02045	4.08e-160	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.98
COGEGGMA_02046	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COGEGGMA_02047	4.82e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_02048	3.48e-195	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_02049	9.77e-160	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02050	1.36e-79	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_02051	0.0	-	-	-	L	ko:K06400	-	ko00000	Psort location Cytoplasmic, score
COGEGGMA_02052	1.11e-07	-	-	-	-	-	-	-	-
COGEGGMA_02053	1e-67	-	-	-	L	-	-	-	Toxic component of a toxin-antitoxin (TA) module
COGEGGMA_02054	4.19e-74	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score 8.87
COGEGGMA_02055	1.13e-156	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02056	4.06e-158	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_02057	1.06e-166	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COGEGGMA_02058	8.92e-118	-	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
COGEGGMA_02059	4.75e-28	-	2.7.13.3	-	K	ko:K07675	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	response regulator
COGEGGMA_02060	7.74e-112	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_02061	5.5e-284	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02062	1.41e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02063	8.05e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_02064	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
COGEGGMA_02065	9.75e-276	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
COGEGGMA_02066	3.99e-134	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02067	1.22e-310	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02068	2.39e-233	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02069	3.03e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02070	0.0	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02071	0.0	-	-	-	L	-	-	-	PFAM Transposase
COGEGGMA_02072	6.65e-127	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02073	3.17e-53	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_02074	2.27e-11	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02075	1.91e-125	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	solute-binding protein
COGEGGMA_02076	1.99e-106	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
COGEGGMA_02077	6.15e-113	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease protein
COGEGGMA_02078	1.31e-232	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
COGEGGMA_02079	4.83e-283	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
COGEGGMA_02080	1.91e-173	-	-	-	M	-	-	-	Nucleotidyl transferase
COGEGGMA_02081	1.69e-209	-	-	-	M	-	-	-	Phosphotransferase enzyme family
COGEGGMA_02082	4.9e-215	fieF	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COGEGGMA_02083	0.0	ppk1	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COGEGGMA_02084	7.1e-170	-	-	-	L	-	-	-	PFAM Transposase, Mutator
COGEGGMA_02085	2.55e-27	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02086	1e-304	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
COGEGGMA_02087	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02088	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02089	4.55e-206	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
COGEGGMA_02090	5.15e-138	-	-	-	U	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02091	2.16e-185	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02092	3.6e-304	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_02093	0.0	-	-	-	T	-	-	-	diguanylate cyclase
COGEGGMA_02094	8.39e-194	-	-	-	P	ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02095	8.79e-208	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems permease components
COGEGGMA_02096	1.94e-316	-	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02097	5.17e-129	-	-	-	-	-	-	-	-
COGEGGMA_02098	6.16e-210	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02099	2.13e-205	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02100	4.47e-31	-	-	-	-	-	-	-	-
COGEGGMA_02101	1.61e-274	-	-	-	CO	-	-	-	AhpC/TSA family
COGEGGMA_02102	7.46e-157	cutR	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02103	5.99e-266	arlS	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COGEGGMA_02104	9.73e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
COGEGGMA_02105	2.64e-98	-	-	-	S	ko:K09706	-	ko00000	Protein of unknown function (DUF1284)
COGEGGMA_02106	1.52e-201	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02107	1.28e-162	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.98
COGEGGMA_02108	2.86e-186	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
COGEGGMA_02109	4.55e-131	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
COGEGGMA_02110	2.98e-149	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COGEGGMA_02111	0.0	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02112	1.17e-07	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
COGEGGMA_02113	1.57e-313	clcA	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
COGEGGMA_02114	1.5e-76	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02115	0.0	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02116	1.66e-246	-	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
COGEGGMA_02117	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02118	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COGEGGMA_02119	1.12e-116	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02120	5.75e-141	thrH	2.7.1.39, 3.1.3.3	-	E	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
COGEGGMA_02121	2.18e-244	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
COGEGGMA_02122	1.07e-09	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02123	4.57e-124	idi	-	-	I	-	-	-	NUDIX domain
COGEGGMA_02124	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
COGEGGMA_02125	3.5e-249	appF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_02126	7.89e-245	oppD	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_02127	8.96e-308	oppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02128	2.29e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02129	0.0	pgi	2.2.1.2, 5.3.1.9	-	G	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
COGEGGMA_02130	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COGEGGMA_02131	3.96e-102	-	3.13.1.6	-	S	ko:K21140	ko04122,map04122	ko00000,ko00001,ko01000	Mov34 MPN PAD-1 family
COGEGGMA_02132	5.7e-198	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
COGEGGMA_02133	1.98e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	TIGRFAM thiamine biosynthesis protein ThiS
COGEGGMA_02134	1.94e-66	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
COGEGGMA_02135	5.02e-52	-	-	-	O	-	-	-	Sulfurtransferase TusA
COGEGGMA_02136	3.01e-194	-	-	-	C	-	-	-	PFAM nitrite and sulphite reductase 4Fe-4S
COGEGGMA_02137	2.41e-205	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02138	1.32e-61	-	-	-	-	-	-	-	-
COGEGGMA_02139	2.11e-63	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COGEGGMA_02140	1.49e-43	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
COGEGGMA_02141	1.47e-70	-	-	-	-	-	-	-	-
COGEGGMA_02142	9.01e-180	-	-	-	S	-	-	-	Protein of unknown function DUF134
COGEGGMA_02143	4.92e-151	-	-	-	K	ko:K01420	-	ko00000,ko03000	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
COGEGGMA_02144	0.0	cdr	-	-	P	-	-	-	pyridine nucleotide-disulphide oxidoreductase dimerisation
COGEGGMA_02145	1.63e-63	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COGEGGMA_02146	8.27e-152	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02147	6.23e-62	-	-	-	L	-	-	-	recombinase activity
COGEGGMA_02148	5.02e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COGEGGMA_02149	2.51e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COGEGGMA_02150	3.29e-154	-	-	-	K	ko:K01420	-	ko00000,ko03000	Psort location Cytoplasmic, score
COGEGGMA_02151	0.0	cdr	-	-	P	-	-	-	pyridine nucleotide-disulphide oxidoreductase dimerisation
COGEGGMA_02152	2.25e-70	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
COGEGGMA_02153	2.05e-66	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Psort location Cytoplasmic, score
COGEGGMA_02154	8.25e-167	baiA	1.1.1.100, 1.1.1.159	-	IQ	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
COGEGGMA_02155	2.63e-241	-	-	-	T	-	-	-	diguanylate cyclase
COGEGGMA_02156	2.4e-182	-	-	-	S	ko:K09861	-	ko00000	Peroxide stress protein YaaA
COGEGGMA_02157	2.19e-84	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
COGEGGMA_02158	2.78e-13	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Antioxidant, AhpC TSA family
COGEGGMA_02159	7.5e-23	-	-	-	-	-	-	-	-
COGEGGMA_02160	2.3e-96	-	-	-	-	-	-	-	-
COGEGGMA_02161	6.78e-42	-	-	-	S	-	-	-	Sporulation initiation factor Spo0A C terminal
COGEGGMA_02162	2.38e-99	-	-	-	P	ko:K07216	-	ko00000	Hemerythrin HHE cation binding domain
COGEGGMA_02163	4.95e-37	rd	-	-	C	-	-	-	PFAM Rubredoxin-type Fe(Cys)4 protein
COGEGGMA_02164	2e-90	-	-	-	-	-	-	-	-
COGEGGMA_02165	6.53e-133	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02166	5.55e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02167	4.07e-43	-	3.4.21.88	-	L	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	LexA DNA binding domain
COGEGGMA_02168	1.45e-150	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
COGEGGMA_02169	5e-124	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COGEGGMA_02170	9.11e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02171	2.07e-217	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
COGEGGMA_02172	1.95e-171	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
COGEGGMA_02173	1.05e-153	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	acid ABC transporter
COGEGGMA_02174	3.25e-145	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
COGEGGMA_02175	3.47e-154	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
COGEGGMA_02176	1.13e-172	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02177	6.06e-145	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02178	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02179	1.05e-298	bioA	2.6.1.113, 2.6.1.55, 2.6.1.62, 2.6.1.77	-	H	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COGEGGMA_02180	2.81e-166	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COGEGGMA_02181	1.79e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COGEGGMA_02182	2.73e-133	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
COGEGGMA_02183	2.25e-17	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
COGEGGMA_02184	1.66e-101	-	-	-	S	-	-	-	Putative threonine/serine exporter
COGEGGMA_02185	9.34e-176	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02187	5.86e-70	-	-	-	-	-	-	-	-
COGEGGMA_02188	4.52e-316	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02189	6.62e-128	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG COG0671 Membrane-associated phospholipid phosphatase
COGEGGMA_02190	5.19e-277	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02191	4.22e-136	-	-	-	F	-	-	-	Cytidylate kinase-like family
COGEGGMA_02192	2.71e-193	-	-	-	C	-	-	-	FAD binding domain in molybdopterin dehydrogenase
COGEGGMA_02193	6.91e-111	hcrC	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02194	0.0	xdhD	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02195	1.43e-252	-	-	-	-	-	-	-	-
COGEGGMA_02196	2.52e-203	-	-	-	-	-	-	-	-
COGEGGMA_02197	0.0	mleN_1	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02199	2.63e-210	-	-	-	T	-	-	-	sh3 domain protein
COGEGGMA_02200	4.75e-247	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
COGEGGMA_02201	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COGEGGMA_02202	4.85e-231	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COGEGGMA_02203	4.45e-133	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_02204	2.99e-49	-	-	-	-	-	-	-	-
COGEGGMA_02205	6.01e-141	-	-	-	S	-	-	-	Zinc dependent phospholipase C
COGEGGMA_02206	0.0	-	-	-	M	-	-	-	NlpC/P60 family
COGEGGMA_02208	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
COGEGGMA_02209	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02210	3.05e-197	bglG	-	-	K	ko:K03480	-	ko00000,ko03000	CAT RNA binding domain
COGEGGMA_02211	1.45e-112	-	-	-	-	-	-	-	-
COGEGGMA_02212	1.65e-270	-	-	-	M	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
COGEGGMA_02214	1.19e-41	-	-	-	N	-	-	-	Domain of unknown function (DUF5057)
COGEGGMA_02215	4.82e-25	-	-	-	-	-	-	-	-
COGEGGMA_02216	1.35e-154	-	-	-	Q	-	-	-	Phosphate propanoyltransferase
COGEGGMA_02217	5.58e-292	-	-	-	D	-	-	-	Transglutaminase-like superfamily
COGEGGMA_02218	9.01e-160	-	-	-	-	-	-	-	-
COGEGGMA_02219	4.18e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COGEGGMA_02220	0.0	ykpA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02221	2.17e-93	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02222	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
COGEGGMA_02223	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02224	3.46e-219	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02225	1.77e-89	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02226	6.24e-245	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
COGEGGMA_02227	3.68e-125	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase
COGEGGMA_02228	4.31e-183	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
COGEGGMA_02229	4.01e-87	-	-	-	H	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02230	2.18e-149	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02231	0.0	ssnA	3.5.4.40	-	F	ko:K20810	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02232	0.0	-	1.97.1.9	-	C	ko:K12527	ko00450,map00450	ko00000,ko00001,ko01000	FAD binding domain
COGEGGMA_02233	0.0	mop	-	-	C	-	-	-	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
COGEGGMA_02234	3.71e-94	-	-	-	C	-	-	-	4Fe-4S binding domain
COGEGGMA_02235	0.0	xdhA	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
COGEGGMA_02236	3.31e-205	xdhB	1.17.1.4	-	C	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
COGEGGMA_02237	4.4e-117	cutS	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
COGEGGMA_02238	2.75e-212	-	-	-	S	ko:K07402	-	ko00000	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
COGEGGMA_02239	1.05e-164	yqeC	-	-	H	-	-	-	selenium-dependent hydroxylase accessory protein YqeC
COGEGGMA_02240	4.3e-159	ygfJ	2.7.7.76	-	S	ko:K07141	ko00790,map00790	ko00000,ko00001,ko01000	MobA-like NTP transferase domain
COGEGGMA_02241	2.38e-224	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
COGEGGMA_02242	7.38e-295	ygeW	-	-	E	-	-	-	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
COGEGGMA_02243	0.0	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02244	3.32e-304	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
COGEGGMA_02245	5.37e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
COGEGGMA_02246	4.78e-31	-	-	-	-	-	-	-	-
COGEGGMA_02248	0.0	leuA	2.3.3.13	-	H	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COGEGGMA_02249	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_02250	1.1e-187	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COGEGGMA_02251	0.0	-	-	-	Q	ko:K06987	-	ko00000	Succinylglutamate desuccinylase / Aspartoacylase family
COGEGGMA_02252	4.31e-193	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall hydrolase
COGEGGMA_02253	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02254	4.89e-264	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
COGEGGMA_02255	3.4e-200	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
COGEGGMA_02256	7.46e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COGEGGMA_02257	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Psort location CytoplasmicMembrane, score
COGEGGMA_02258	3.15e-256	-	-	-	S	-	-	-	Tetratricopeptide repeat
COGEGGMA_02259	8.64e-107	rlmH	2.1.1.177	-	H	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COGEGGMA_02260	4.42e-141	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02261	2.8e-63	-	-	-	S	-	-	-	COG NOG13846 non supervised orthologous group
COGEGGMA_02262	1.46e-283	yqfD	-	-	S	ko:K06438	-	ko00000	sporulation protein
COGEGGMA_02263	4.1e-227	phoH	-	-	T	ko:K06217	-	ko00000	Psort location Cytoplasmic, score 9.98
COGEGGMA_02264	5.79e-112	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COGEGGMA_02265	2.03e-190	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COGEGGMA_02266	2.05e-42	ynzC	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02267	1.28e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02268	8.03e-295	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COGEGGMA_02269	0.0	-	-	-	-	-	-	-	-
COGEGGMA_02270	2.89e-222	-	-	-	E	-	-	-	Zinc carboxypeptidase
COGEGGMA_02271	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COGEGGMA_02272	6.4e-315	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02273	1.36e-66	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
COGEGGMA_02274	0.0	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
COGEGGMA_02275	3.12e-250	rsmH2	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COGEGGMA_02276	1.33e-135	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_02277	1.79e-70	-	-	-	-	-	-	-	-
COGEGGMA_02278	2.85e-154	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
COGEGGMA_02279	7.21e-143	-	-	-	S	-	-	-	Protease prsW family
COGEGGMA_02280	1.78e-73	-	-	-	-	-	-	-	-
COGEGGMA_02281	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
COGEGGMA_02282	9.1e-163	-	-	-	L	-	-	-	MerR family regulatory protein
COGEGGMA_02283	4.62e-255	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
COGEGGMA_02284	2.4e-295	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	Belongs to the serpin family
COGEGGMA_02285	1.79e-121	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02286	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COGEGGMA_02287	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COGEGGMA_02288	1.87e-221	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COGEGGMA_02289	2.2e-312	ynbB	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02290	2.62e-283	-	-	-	S	ko:K07007	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02291	0.0	-	-	-	S	ko:K07137	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02292	2.22e-171	radC	-	-	E	ko:K03630	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02293	1.2e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Psort location Cytoplasmic, score
COGEGGMA_02294	5.94e-208	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
COGEGGMA_02295	8.38e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
COGEGGMA_02296	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
COGEGGMA_02297	3.12e-178	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Psort location Cytoplasmic, score 8.87
COGEGGMA_02298	1.38e-59	minE	-	-	D	ko:K03608	-	ko00000,ko03036,ko04812	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
COGEGGMA_02299	2.14e-245	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02300	2.14e-279	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_02301	2.05e-126	-	-	-	S	ko:K06952	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02302	6.89e-75	-	-	-	-	-	-	-	-
COGEGGMA_02303	1.42e-43	-	-	-	-	-	-	-	-
COGEGGMA_02304	2.39e-55	-	-	-	L	-	-	-	RelB antitoxin
COGEGGMA_02305	4.54e-63	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	addiction module toxin, RelE StbE family
COGEGGMA_02306	1.97e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
COGEGGMA_02307	1.35e-155	-	-	-	-	-	-	-	-
COGEGGMA_02308	4.08e-117	-	-	-	-	-	-	-	-
COGEGGMA_02309	8.07e-163	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_02312	0.0	pbuX	-	-	F	ko:K03458	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02313	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COGEGGMA_02314	6.25e-132	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02315	3.14e-231	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COGEGGMA_02316	7.34e-179	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
COGEGGMA_02317	2.3e-145	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02318	1.21e-287	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COGEGGMA_02319	5.43e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COGEGGMA_02320	5.51e-198	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02321	4.3e-228	dagK	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
COGEGGMA_02322	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
COGEGGMA_02323	2.44e-213	-	-	-	S	-	-	-	ATPase family associated with various cellular activities (AAA)
COGEGGMA_02324	0.0	-	-	-	P	-	-	-	von Willebrand factor (vWF) type A domain
COGEGGMA_02325	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02326	1.54e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02327	5.25e-200	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
COGEGGMA_02328	1.19e-255	cdaR_3	-	-	QT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02329	1.28e-155	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Psort location CytoplasmicMembrane, score
COGEGGMA_02330	2.82e-205	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
COGEGGMA_02331	2.81e-278	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
COGEGGMA_02332	5.13e-211	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02333	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
COGEGGMA_02334	5.74e-148	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_02335	1.07e-35	-	-	-	-	-	-	-	-
COGEGGMA_02336	2.72e-78	-	-	-	S	-	-	-	SdpI/YhfL protein family
COGEGGMA_02337	4.55e-76	-	-	-	-	-	-	-	-
COGEGGMA_02338	3.25e-64	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_02339	0.0	-	-	-	K	-	-	-	Transcriptional regulator
COGEGGMA_02340	0.0	-	-	-	L	-	-	-	AlwI restriction endonuclease
COGEGGMA_02341	0.0	dam	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (Adenine-specific)
COGEGGMA_02342	9.47e-43	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_02343	4.78e-50	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
COGEGGMA_02344	6.46e-83	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_02345	2.17e-304	-	-	-	M	-	-	-	plasmid recombination
COGEGGMA_02346	2.83e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF5348)
COGEGGMA_02347	5.16e-50	-	-	-	-	-	-	-	-
COGEGGMA_02348	1.19e-259	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02349	5.43e-255	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_02350	1.15e-39	-	-	-	-	-	-	-	-
COGEGGMA_02351	2.7e-121	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02352	4.24e-07	-	-	-	-	-	-	-	-
COGEGGMA_02353	1.21e-208	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02354	4.86e-42	-	-	-	K	-	-	-	Helix-turn-helix
COGEGGMA_02355	3.57e-39	-	-	-	S	-	-	-	Cysteine-rich KTR
COGEGGMA_02356	5.09e-238	-	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COGEGGMA_02357	5.56e-77	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_02358	1.05e-277	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02359	2.83e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF5348)
COGEGGMA_02360	7.33e-50	-	-	-	-	-	-	-	-
COGEGGMA_02361	6.51e-253	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02362	3.2e-265	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_02363	6.21e-31	-	-	-	-	-	-	-	-
COGEGGMA_02364	5.92e-109	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_02365	5.31e-95	-	-	-	-	-	-	-	-
COGEGGMA_02366	4.47e-177	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_02367	1.41e-56	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COGEGGMA_02370	8.06e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
COGEGGMA_02371	1.12e-246	tsaD	2.3.1.234	-	H	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COGEGGMA_02372	1.62e-225	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COGEGGMA_02373	6.29e-100	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
COGEGGMA_02374	2.76e-162	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
COGEGGMA_02375	1.05e-102	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	Psort location Cytoplasmic, score 8.87
COGEGGMA_02376	9.9e-126	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COGEGGMA_02377	5.05e-153	yvyE	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02378	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
COGEGGMA_02379	1.18e-224	glcK	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02380	4.97e-220	hprK	-	-	H	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COGEGGMA_02381	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COGEGGMA_02382	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COGEGGMA_02383	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02384	2.13e-178	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
COGEGGMA_02385	9.99e-237	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	solute-binding protein
COGEGGMA_02386	2.38e-155	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
COGEGGMA_02387	4.44e-165	-	-	-	G	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02388	3.53e-139	ugpC_1	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG COG3839 ABC-type sugar transport systems, ATPase components
COGEGGMA_02389	3.33e-81	-	-	-	G	ko:K02566	-	ko00000	Haloacid dehalogenase-like hydrolase
COGEGGMA_02390	4.23e-160	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
COGEGGMA_02391	2e-198	nit	-	-	S	-	-	-	Carbon-nitrogen hydrolase
COGEGGMA_02392	2.6e-233	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
COGEGGMA_02393	1.92e-302	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02394	2e-206	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02395	4.65e-194	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02396	0.0	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
COGEGGMA_02397	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase family M20/M25/M40
COGEGGMA_02398	5.85e-225	-	-	-	S	-	-	-	aldo keto reductase
COGEGGMA_02399	7.05e-282	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02400	1.87e-170	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
COGEGGMA_02401	1.53e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COGEGGMA_02402	0.0	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
COGEGGMA_02403	0.0	-	-	-	I	-	-	-	Carboxyl transferase domain
COGEGGMA_02404	2.66e-129	-	-	-	C	-	-	-	Oxaloacetate decarboxylase, gamma chain
COGEGGMA_02405	7.37e-54	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
COGEGGMA_02406	3.46e-265	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02407	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
COGEGGMA_02408	5.25e-314	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
COGEGGMA_02409	9.69e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
COGEGGMA_02410	3.08e-209	ispH	1.17.7.4	-	C	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COGEGGMA_02411	4.23e-247	ispH	1.17.7.4	-	J	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Psort location Cytoplasmic, score 9.98
COGEGGMA_02412	7.76e-181	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
COGEGGMA_02413	1.29e-164	-	-	-	M	-	-	-	Chain length determinant protein
COGEGGMA_02414	2.08e-13	-	-	-	D	-	-	-	Capsular exopolysaccharide family
COGEGGMA_02415	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate synthase pyruvate phosphate dikinase
COGEGGMA_02416	1.11e-302	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
COGEGGMA_02417	1.88e-223	lacX	-	-	G	-	-	-	COG COG2017 Galactose mutarotase and related enzymes
COGEGGMA_02418	2.43e-202	metH	2.1.1.13	-	H	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02419	3.61e-266	-	-	-	C	-	-	-	Domain of unknown function (DUF362)
COGEGGMA_02420	0.0	-	-	-	G	-	-	-	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COGEGGMA_02421	1.22e-248	potD	-	-	P	ko:K11069,ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02422	0.0	potD	-	-	P	ko:K11069,ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Spermidine putrescine-binding periplasmic protein
COGEGGMA_02423	7.09e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02424	7.08e-250	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COGEGGMA_02425	1.79e-170	-	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02426	6.35e-197	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02427	8.04e-261	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COGEGGMA_02430	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COGEGGMA_02431	4.69e-236	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02432	2.87e-246	-	-	-	K	-	-	-	response regulator
COGEGGMA_02433	1.26e-75	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
COGEGGMA_02434	1.29e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COGEGGMA_02435	2.72e-208	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	pyridine
COGEGGMA_02436	2.71e-66	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
COGEGGMA_02437	0.0	-	1.21.98.3	-	C	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02438	2.09e-10	-	-	-	-	-	-	-	-
COGEGGMA_02439	2.42e-132	hypE	-	-	O	ko:K04655	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02440	1.94e-120	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COGEGGMA_02441	5.18e-134	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
COGEGGMA_02442	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
COGEGGMA_02443	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02444	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02445	6.64e-170	srrA_2	-	-	T	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_02446	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COGEGGMA_02448	2.22e-287	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COGEGGMA_02449	4.84e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Psort location Cytoplasmic, score 8.87
COGEGGMA_02450	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COGEGGMA_02451	1.65e-34	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02452	0.0	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
COGEGGMA_02453	4.92e-242	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
COGEGGMA_02454	2.65e-34	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COGEGGMA_02455	1.19e-33	-	-	-	-	-	-	-	-
COGEGGMA_02456	6.29e-71	-	-	-	P	-	-	-	Rhodanese Homology Domain
COGEGGMA_02457	2.5e-132	yfcE	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02458	2.72e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02459	1.59e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COGEGGMA_02460	8.66e-116	yfcE1	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02468	1.7e-162	-	-	-	K	-	-	-	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COGEGGMA_02469	7.72e-165	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Phosphorylase superfamily
COGEGGMA_02470	4.01e-78	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
COGEGGMA_02471	5.11e-214	-	-	-	EG	-	-	-	EamA-like transporter family
COGEGGMA_02472	9.63e-306	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	xanthine uracil permease family protein K06901
COGEGGMA_02473	1.27e-312	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases
COGEGGMA_02474	4.8e-240	-	-	-	S	-	-	-	AI-2E family transporter
COGEGGMA_02475	5.34e-81	-	-	-	S	-	-	-	Penicillinase repressor
COGEGGMA_02476	2.07e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_02477	1.97e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COGEGGMA_02478	1.93e-286	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COGEGGMA_02479	1.86e-213	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
COGEGGMA_02480	4.94e-288	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
COGEGGMA_02481	1.08e-306	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_02482	4.46e-166	-	-	-	KT	-	-	-	LytTr DNA-binding domain
COGEGGMA_02483	2.25e-92	-	-	-	U	-	-	-	domain, Protein
COGEGGMA_02484	0.000148	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
COGEGGMA_02485	1.98e-278	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
COGEGGMA_02486	9.47e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COGEGGMA_02487	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
COGEGGMA_02488	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
COGEGGMA_02489	4.82e-254	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
COGEGGMA_02490	8.14e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	COG COG1862 Preprotein translocase subunit YajC
COGEGGMA_02491	2.08e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COGEGGMA_02492	0.0	hgdC2	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02493	0.0	spoVB1	-	-	S	ko:K06409	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02494	4.9e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COGEGGMA_02495	6.86e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COGEGGMA_02496	1.58e-153	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COGEGGMA_02497	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02498	8.87e-162	srrA_6	-	-	T	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_02500	1.79e-103	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02501	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
COGEGGMA_02502	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase 36 superfamily, catalytic domain
COGEGGMA_02503	0.0	-	-	-	G	-	-	-	Glycosyltransferase family 36
COGEGGMA_02504	8.73e-191	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02505	3.06e-165	-	-	-	S	ko:K06940	-	ko00000	Psort location Cytoplasmic, score
COGEGGMA_02506	7.23e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02507	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COGEGGMA_02508	1.24e-155	-	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
COGEGGMA_02509	1.62e-158	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02510	1.65e-243	kfoC_2	-	-	M	-	-	-	Glycosyltransferase like family 2
COGEGGMA_02511	2.31e-255	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score
COGEGGMA_02512	1.74e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
COGEGGMA_02513	0.0	-	-	-	S	-	-	-	ErfK YbiS YcfS YnhG
COGEGGMA_02514	4.41e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02515	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COGEGGMA_02516	4.66e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02517	1.11e-41	-	-	-	K	-	-	-	Helix-turn-helix domain
COGEGGMA_02518	3.25e-47	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
COGEGGMA_02519	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COGEGGMA_02520	2.21e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_02521	1.51e-238	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02522	3.68e-160	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02523	2.17e-39	-	-	-	K	-	-	-	trisaccharide binding
COGEGGMA_02524	5.29e-67	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_02525	3.13e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
COGEGGMA_02526	1.05e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COGEGGMA_02527	1.57e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COGEGGMA_02528	2.89e-181	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGEGGMA_02529	1.54e-249	ecfA2	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGEGGMA_02530	3.32e-203	ecfA2	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGEGGMA_02531	2.08e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
COGEGGMA_02532	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
COGEGGMA_02533	6.6e-312	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COGEGGMA_02534	2.01e-133	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COGEGGMA_02535	1.26e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COGEGGMA_02536	1.65e-115	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_02537	3.23e-310	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02538	1.64e-103	-	-	-	K	-	-	-	helix_turn_helix ASNC type
COGEGGMA_02539	3.24e-308	mepA_2	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02540	1.06e-194	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
COGEGGMA_02541	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02542	0.0	-	3.1.3.5, 3.6.1.45	-	FG	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	ABC transporter substrate-binding protein
COGEGGMA_02543	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02544	3.22e-207	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02545	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
COGEGGMA_02546	4.35e-283	-	-	-	E	-	-	-	Peptidase dimerisation domain
COGEGGMA_02547	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02548	2.31e-288	-	-	-	S	-	-	-	COG NOG08812 non supervised orthologous group
COGEGGMA_02549	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase catalytic
COGEGGMA_02550	3.61e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
COGEGGMA_02551	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
COGEGGMA_02552	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02553	4.87e-128	-	-	-	S	-	-	-	Domain of unknown function, E. rectale Gene description (DUF3877)
COGEGGMA_02554	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Psort location Cytoplasmic, score 8.87
COGEGGMA_02555	1.68e-156	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02556	1.05e-36	-	-	-	-	-	-	-	-
COGEGGMA_02557	2.91e-179	thiF	-	-	H	ko:K22132	-	ko00000,ko03016	Psort location Cytoplasmic, score 8.87
COGEGGMA_02558	6.32e-274	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02559	4.1e-224	-	-	-	EQ	-	-	-	Peptidase family S58
COGEGGMA_02560	1.71e-127	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02561	1.93e-57	ilvH_1	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0440 Acetolactate synthase, small (regulatory) subunit
COGEGGMA_02562	7.44e-169	-	-	-	E	ko:K04477	-	ko00000	PHP domain protein
COGEGGMA_02563	3.88e-303	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COGEGGMA_02564	9.88e-111	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Small subunit of acetolactate synthase
COGEGGMA_02565	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
COGEGGMA_02566	6.85e-132	-	-	-	K	-	-	-	Cupin domain
COGEGGMA_02567	7.77e-301	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
COGEGGMA_02568	3.86e-142	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02569	0.0	-	-	-	E	-	-	-	Amino acid permease
COGEGGMA_02570	1.66e-269	-	1.1.1.1	-	C	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
COGEGGMA_02571	3.04e-154	rnhA	-	-	L	ko:K06993	-	ko00000	Caulimovirus viroplasmin
COGEGGMA_02572	1.23e-253	-	-	-	S	ko:K07035	-	ko00000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02573	2.61e-147	-	-	-	S	-	-	-	Membrane
COGEGGMA_02574	2.31e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COGEGGMA_02575	9.07e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02576	1.05e-296	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
COGEGGMA_02577	1.76e-216	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
COGEGGMA_02578	5.66e-207	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02579	2.91e-196	-	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02580	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Psort location Cellwall, score
COGEGGMA_02581	4.82e-183	-	-	-	P	-	-	-	ATPases associated with a variety of cellular activities
COGEGGMA_02582	1.05e-176	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
COGEGGMA_02583	6.07e-228	-	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein
COGEGGMA_02584	2.91e-189	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COGEGGMA_02585	6.15e-161	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_02586	7.13e-123	yvdD	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
COGEGGMA_02587	7.04e-199	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COGEGGMA_02588	1.39e-295	-	-	-	S	-	-	-	Belongs to the UPF0597 family
COGEGGMA_02589	2e-154	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
COGEGGMA_02590	1.28e-193	-	-	-	S	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02591	4.46e-42	-	-	-	E	-	-	-	Belongs to the ABC transporter superfamily
COGEGGMA_02592	0.0	-	-	-	T	-	-	-	PAS fold
COGEGGMA_02593	1e-248	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
COGEGGMA_02594	0.0	-	-	-	Q	-	-	-	Condensation domain
COGEGGMA_02595	5.12e-42	-	-	-	Q	-	-	-	Phosphopantetheine attachment site
COGEGGMA_02596	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
COGEGGMA_02597	2.02e-137	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02598	5.98e-55	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_02599	3.3e-285	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
COGEGGMA_02600	4.3e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COGEGGMA_02601	3.05e-132	-	-	-	F	-	-	-	Cytidylate kinase-like family
COGEGGMA_02602	7.19e-33	-	-	-	C	-	-	-	4Fe-4S binding domain
COGEGGMA_02603	1.59e-129	-	-	-	C	-	-	-	4Fe-4S binding domain
COGEGGMA_02604	8.52e-173	-	-	-	S	-	-	-	Purple acid Phosphatase, N-terminal domain
COGEGGMA_02605	1.86e-133	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02606	4.56e-152	-	-	-	T	-	-	-	EAL domain
COGEGGMA_02607	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
COGEGGMA_02608	3.05e-280	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
COGEGGMA_02609	0.0	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02610	0.0	-	-	-	G	ko:K10200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Carbohydrate ABC transporter
COGEGGMA_02611	7.73e-199	-	-	-	P	ko:K10201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02612	6.33e-189	-	-	-	P	ko:K10202	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02613	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
COGEGGMA_02615	7.97e-06	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02616	1.76e-235	-	-	-	K	ko:K03484	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.98
COGEGGMA_02617	1.8e-218	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
COGEGGMA_02618	1.85e-208	-	-	-	P	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02619	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system periplasmic component
COGEGGMA_02620	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
COGEGGMA_02621	6.35e-48	sacC5	2.7.1.4, 3.2.1.80	-	G	ko:K00847,ko:K03332	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COGEGGMA_02622	0.0	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
COGEGGMA_02623	5.41e-47	-	-	-	-	-	-	-	-
COGEGGMA_02624	7.14e-311	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
COGEGGMA_02625	1.26e-137	-	-	-	F	-	-	-	COG NOG14451 non supervised orthologous group
COGEGGMA_02626	0.0	glgA	-	-	G	-	-	-	Synthesizes alpha-1,4-glucan chains using ADP-glucose
COGEGGMA_02627	7.53e-157	-	-	-	Q	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
COGEGGMA_02628	3.19e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02629	1.73e-44	-	-	-	Q	-	-	-	Leucine carboxyl methyltransferase
COGEGGMA_02630	1.2e-151	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02631	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG COG1132 ABC-type multidrug transport system, ATPase and permease components
COGEGGMA_02632	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG COG1132 ABC-type multidrug transport system, ATPase and permease components
COGEGGMA_02633	1.91e-261	-	-	-	S	ko:K07003	-	ko00000	ECF transporter, substrate-specific component
COGEGGMA_02634	3.73e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
COGEGGMA_02635	1.62e-46	-	-	-	S	ko:K07149	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_02636	7.63e-72	-	-	-	I	-	-	-	Alpha/beta hydrolase family
COGEGGMA_02637	8.38e-42	-	-	-	K	-	-	-	Transcriptional regulator
COGEGGMA_02638	3.49e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF3791)
COGEGGMA_02639	1.43e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
COGEGGMA_02640	4.88e-49	-	-	-	-	-	-	-	-
COGEGGMA_02641	8.43e-295	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02642	9.4e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02643	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02644	4.8e-224	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02645	1.34e-200	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02646	2.64e-270	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02647	2.97e-269	-	-	-	-	-	-	-	-
COGEGGMA_02648	1.74e-52	-	-	-	-	-	-	-	-
COGEGGMA_02649	2.03e-136	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_02650	3.72e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_02651	1.83e-75	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
COGEGGMA_02652	1.19e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF3796)
COGEGGMA_02653	8.83e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
COGEGGMA_02654	8.2e-210	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COGEGGMA_02655	3.93e-140	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COGEGGMA_02656	1.04e-83	-	-	-	K	ko:K07467	-	ko00000	DNA-binding helix-turn-helix protein
COGEGGMA_02657	3.09e-41	-	-	-	S	-	-	-	COG NOG13238 non supervised orthologous group
COGEGGMA_02658	1.82e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
COGEGGMA_02659	4.14e-72	-	-	-	S	ko:K19092	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
COGEGGMA_02660	2.67e-24	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02661	2.11e-127	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
COGEGGMA_02662	2.98e-155	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
COGEGGMA_02663	1.02e-181	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02664	0.0	tetP	-	-	J	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_02665	4.31e-140	-	-	-	S	ko:K01421	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_02666	9.59e-73	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02667	5.11e-107	greA_2	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COGEGGMA_02668	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02669	7.77e-159	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	positive response regulator for pho regulon
COGEGGMA_02670	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COGEGGMA_02671	4.77e-312	-	-	-	G	-	-	-	ABC transporter, solute-binding protein
COGEGGMA_02672	5.28e-221	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02673	3.23e-310	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, solute-binding protein
COGEGGMA_02674	7.79e-211	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02675	9.48e-204	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02676	4.16e-78	-	-	-	G	-	-	-	Cupin domain
COGEGGMA_02677	6.83e-76	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
COGEGGMA_02678	5.62e-37	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02679	7.25e-88	-	-	-	-	-	-	-	-
COGEGGMA_02680	2.08e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
COGEGGMA_02681	9.24e-317	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, N-terminal domain
COGEGGMA_02682	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na+/Pi-cotransporter
COGEGGMA_02683	6.79e-55	-	-	-	-	-	-	-	-
COGEGGMA_02684	2.52e-16	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02685	1.26e-139	-	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
COGEGGMA_02686	9.56e-303	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02687	3.65e-140	-	-	-	-	-	-	-	-
COGEGGMA_02688	1.61e-157	-	-	-	-	-	-	-	-
COGEGGMA_02689	8.33e-163	-	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_02690	1.43e-246	-	-	-	-	-	-	-	-
COGEGGMA_02691	8.25e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02692	4.69e-43	-	-	-	-	-	-	-	-
COGEGGMA_02693	3.86e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02694	5.63e-316	-	-	-	D	-	-	-	MobA MobL family protein
COGEGGMA_02695	0.0	-	-	-	L	-	-	-	Virulence-associated protein E
COGEGGMA_02696	1.65e-35	-	-	-	-	-	-	-	-
COGEGGMA_02698	1.9e-171	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
COGEGGMA_02699	1.81e-132	-	-	-	-	-	-	-	-
COGEGGMA_02700	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COGEGGMA_02701	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COGEGGMA_02702	5.91e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COGEGGMA_02703	2.5e-176	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.87
COGEGGMA_02704	3.43e-205	yaaT	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02705	1.9e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COGEGGMA_02706	1.87e-139	gmk_1	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02707	0.0	speA_1	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02708	2.92e-162	srrA_2	-	-	T	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_02709	4.04e-266	yycG_1	-	-	T	-	-	-	COG COG0642 Signal transduction histidine kinase
COGEGGMA_02710	4.37e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COGEGGMA_02711	1.35e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COGEGGMA_02712	2.62e-111	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COGEGGMA_02713	2.68e-71	-	-	-	L	-	-	-	Transposase
COGEGGMA_02714	5.52e-133	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
COGEGGMA_02715	1.71e-93	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	heptaprenyl diphosphate synthase
COGEGGMA_02716	3.01e-77	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02717	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
COGEGGMA_02718	1.45e-46	-	-	-	C	-	-	-	Heavy metal-associated domain protein
COGEGGMA_02719	1.86e-81	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02720	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	COG COG2217 Cation transport ATPase
COGEGGMA_02721	2.52e-49	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
COGEGGMA_02722	6.61e-110	fur	-	-	L	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
COGEGGMA_02723	1.7e-11	-	-	-	S	-	-	-	Virus attachment protein p12 family
COGEGGMA_02724	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
COGEGGMA_02725	3.27e-42	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
COGEGGMA_02726	7.14e-39	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
COGEGGMA_02727	4.54e-63	-	-	-	S	-	-	-	COG NOG21970 non supervised orthologous group
COGEGGMA_02728	1.74e-291	hydF	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02729	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02730	2.7e-259	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
COGEGGMA_02731	1.91e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02732	2.95e-240	-	-	-	S	-	-	-	Transglutaminase-like superfamily
COGEGGMA_02733	3.04e-105	-	-	-	-	-	-	-	-
COGEGGMA_02734	3.9e-47	-	-	-	-	-	-	-	-
COGEGGMA_02735	2.17e-165	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_02736	5.08e-153	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_02737	2.39e-178	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_02738	4.97e-156	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02739	5.24e-312	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_02740	1.64e-89	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_02741	1.78e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
COGEGGMA_02742	2.99e-219	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_02743	1.86e-216	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02744	1.43e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02745	1.4e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02746	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02747	7.28e-71	gmuA_1	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
COGEGGMA_02748	3.03e-312	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
COGEGGMA_02749	7.99e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
COGEGGMA_02750	5.21e-179	-	-	-	K	-	-	-	transcriptional regulator RpiR family
COGEGGMA_02751	7.54e-21	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_02752	2.75e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
COGEGGMA_02753	0.0	-	-	-	T	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
COGEGGMA_02754	0.0	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02755	0.0	-	-	-	-	-	-	-	-
COGEGGMA_02756	2.82e-198	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
COGEGGMA_02757	3.63e-218	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02758	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_02759	3.48e-213	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02760	1.33e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
COGEGGMA_02761	2.49e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COGEGGMA_02762	0.0	-	-	-	P	ko:K03308	-	ko00000	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02767	2.96e-284	-	-	-	L	-	-	-	Phage integrase family
COGEGGMA_02768	2.45e-276	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02769	3.94e-250	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
COGEGGMA_02770	1.37e-95	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02771	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COGEGGMA_02772	3.47e-215	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02773	6.82e-295	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02774	3.1e-184	-	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
COGEGGMA_02775	1.45e-95	-	-	-	-	-	-	-	-
COGEGGMA_02777	4.1e-221	-	-	-	D	ko:K18640	-	ko00000,ko04812	cell division
COGEGGMA_02778	1.06e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02779	2.68e-74	-	-	-	K	-	-	-	regulator of the anaerobic catobolism of benzoate BzdR K00891
COGEGGMA_02780	2.73e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02781	1.04e-37	-	-	-	S	-	-	-	Helix-turn-helix domain
COGEGGMA_02782	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COGEGGMA_02783	6.13e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02785	1.58e-214	cobW	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02786	9.1e-235	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02787	1.32e-138	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COGEGGMA_02788	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COGEGGMA_02789	1.07e-262	-	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
COGEGGMA_02790	1.77e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02791	1.22e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02792	3.19e-122	nfrA2	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02793	2.59e-96	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02794	7.19e-170	-	-	-	C	-	-	-	PFAM Radical SAM
COGEGGMA_02795	3.14e-87	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
COGEGGMA_02796	3.06e-120	-	-	-	C	-	-	-	Nitroreductase family
COGEGGMA_02797	3.47e-69	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_02798	2.27e-86	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
COGEGGMA_02799	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	haloacid dehalogenase-like hydrolase
COGEGGMA_02800	8.09e-44	-	-	-	P	-	-	-	Heavy metal-associated domain protein
COGEGGMA_02801	0.0	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
COGEGGMA_02802	1.38e-309	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02803	2.16e-43	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
COGEGGMA_02804	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Signal recognition particle receptor beta subunit
COGEGGMA_02805	1.43e-252	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COGEGGMA_02806	4.71e-84	-	-	-	L	-	-	-	Single-strand binding protein family
COGEGGMA_02807	3.73e-94	-	-	-	-	-	-	-	-
COGEGGMA_02808	5.29e-179	-	-	-	K	-	-	-	BRO family, N-terminal domain
COGEGGMA_02809	3.22e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
COGEGGMA_02810	1.22e-75	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
COGEGGMA_02811	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02812	3.08e-43	-	-	-	S	-	-	-	Transposon-encoded protein TnpW
COGEGGMA_02813	2.43e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02814	4.87e-141	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02815	6.5e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02816	0.0	-	-	-	D	-	-	-	MobA MobL family protein
COGEGGMA_02817	7.02e-106	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
COGEGGMA_02818	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02819	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG COG3505 Type IV secretory pathway, VirD4 components
COGEGGMA_02820	2.04e-58	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02821	4.53e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02830	1.19e-194	spoIID	-	-	D	ko:K06381	-	ko00000	COG COG2385 Sporulation protein and related proteins
COGEGGMA_02831	2.65e-192	-	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
COGEGGMA_02832	7.18e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
COGEGGMA_02833	0.0	-	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02834	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_02835	5.28e-53	-	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
COGEGGMA_02836	2.08e-179	-	-	-	S	-	-	-	repeat protein
COGEGGMA_02837	3.1e-154	yqfA	-	-	S	ko:K11068	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_02838	9.44e-189	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
COGEGGMA_02839	1.24e-31	-	-	-	-	-	-	-	-
COGEGGMA_02840	9.48e-237	-	-	-	K	-	-	-	Periplasmic binding protein LacI transcriptional regulator
COGEGGMA_02841	1.14e-292	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_02842	0.0	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02843	8.7e-196	-	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02844	5.87e-181	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02845	0.0	pbg	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02846	0.0	-	2.7.11.1	-	KL	ko:K08282	-	ko00000,ko01000	SNF2 family
COGEGGMA_02847	8.3e-123	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
COGEGGMA_02848	1.02e-287	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
COGEGGMA_02849	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COGEGGMA_02851	0.0	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
COGEGGMA_02852	2.89e-75	-	-	-	E	-	-	-	Sodium:alanine symporter family
COGEGGMA_02853	8.4e-150	-	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	orotate phosphoribosyltransferase K00762
COGEGGMA_02854	1.61e-168	phoP_1	-	-	T	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COGEGGMA_02855	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02856	4.69e-176	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Psort location Cytoplasmic, score 8.87
COGEGGMA_02857	2.01e-206	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
COGEGGMA_02858	9.87e-175	-	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02859	7.3e-287	-	-	-	-	-	-	-	-
COGEGGMA_02860	2.62e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COGEGGMA_02861	2.81e-194	cvfB	-	-	S	ko:K00243	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02862	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Psort location Cytoplasmic, score 9.98
COGEGGMA_02863	1.65e-240	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COGEGGMA_02864	0.0	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_02865	5.03e-148	-	-	-	P	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02866	1.82e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Psort location Cytoplasmic, score 8.87
COGEGGMA_02867	4.78e-90	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score 9.26
COGEGGMA_02868	1.41e-151	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
COGEGGMA_02869	1.17e-245	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COGEGGMA_02870	3.05e-192	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin-- acetyl-CoA-carboxylase ligase
COGEGGMA_02871	2.46e-81	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02872	1.03e-240	dus	-	-	H	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGEGGMA_02873	1.94e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COGEGGMA_02874	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
COGEGGMA_02875	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
COGEGGMA_02876	9.23e-245	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_02877	1.27e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
COGEGGMA_02878	1.52e-237	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02879	2.81e-202	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_02880	0.0	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02881	1.05e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1292)
COGEGGMA_02882	4.37e-264	-	-	-	C	ko:K07138	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02883	3.45e-240	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02884	1.98e-297	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_02885	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COGEGGMA_02886	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COGEGGMA_02887	1.61e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4869)
COGEGGMA_02888	7.45e-124	-	-	-	-	-	-	-	-
COGEGGMA_02889	0.0	-	-	-	M	-	-	-	COG3209 Rhs family protein
COGEGGMA_02890	5.41e-293	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
COGEGGMA_02891	2.29e-36	-	3.4.24.40	-	S	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	peptidase inhibitor activity
COGEGGMA_02892	2.11e-132	-	3.4.24.40	-	S	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	peptidase inhibitor activity
COGEGGMA_02894	2.54e-66	-	-	-	-	-	-	-	-
COGEGGMA_02895	4.94e-146	-	-	-	D	-	-	-	Transglutaminase-like superfamily
COGEGGMA_02896	3.86e-36	-	-	-	-	-	-	-	-
COGEGGMA_02897	1.62e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02898	8.46e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
COGEGGMA_02899	0.0	-	-	-	N	-	-	-	cellulase activity
COGEGGMA_02900	9.8e-199	-	-	-	O	-	-	-	dinitrogenase iron-molybdenum cofactor
COGEGGMA_02901	4.82e-228	lytC_3	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
COGEGGMA_02902	4.73e-32	-	3.4.24.40	-	S	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	peptidase inhibitor activity
COGEGGMA_02903	2.37e-226	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02904	5.77e-278	-	-	-	L	-	-	-	Recombinase
COGEGGMA_02905	2.3e-173	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
COGEGGMA_02906	6.37e-93	-	-	-	S	-	-	-	PrcB C-terminal
COGEGGMA_02907	0.0	-	-	-	M	-	-	-	Lysin motif
COGEGGMA_02908	4.7e-204	ispE	2.7.1.148	-	H	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COGEGGMA_02909	4.75e-157	GntR	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02910	0.0	gerA	-	-	EG	ko:K06310	-	ko00000	Psort location CytoplasmicMembrane, score
COGEGGMA_02911	0.0	-	-	-	E	-	-	-	Spore germination protein
COGEGGMA_02912	6.51e-54	-	-	-	-	-	-	-	-
COGEGGMA_02913	2.61e-196	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
COGEGGMA_02914	2.32e-104	ywiB	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02915	7.73e-72	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
COGEGGMA_02916	0.0	-	-	-	G	-	-	-	polysaccharide deacetylase
COGEGGMA_02917	0.0	-	-	-	G	-	-	-	polysaccharide deacetylase
COGEGGMA_02918	1.08e-272	tig_1	-	-	M	ko:K03545	-	ko00000	Bacterial trigger factor protein (TF) C-terminus
COGEGGMA_02919	5.06e-274	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
COGEGGMA_02920	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
COGEGGMA_02921	8.06e-74	-	-	-	S	-	-	-	COG NOG10998 non supervised orthologous group
COGEGGMA_02922	3.42e-84	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
COGEGGMA_02923	5.28e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF3795)
COGEGGMA_02924	0.0	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COGEGGMA_02925	2.1e-290	-	-	-	L	ko:K07467	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_02926	4.78e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF3789)
COGEGGMA_02927	5.89e-42	-	-	-	S	-	-	-	COG NOG13238 non supervised orthologous group
COGEGGMA_02928	5.22e-65	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02929	4.75e-117	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
COGEGGMA_02930	6.25e-122	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
COGEGGMA_02931	2.03e-92	-	-	-	S	-	-	-	TcpE family
COGEGGMA_02932	0.0	-	-	-	S	-	-	-	COG NOG05968 non supervised orthologous group
COGEGGMA_02933	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_02934	3.21e-244	-	-	-	M	-	-	-	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
COGEGGMA_02935	3.29e-205	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
COGEGGMA_02936	8.58e-65	-	-	-	-	-	-	-	-
COGEGGMA_02937	3.02e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
COGEGGMA_02938	7.44e-66	-	-	-	-	-	-	-	-
COGEGGMA_02939	4.11e-46	-	-	-	L	-	-	-	viral genome integration into host DNA
COGEGGMA_02940	1.44e-180	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_02941	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_02942	5.98e-152	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_02943	6.4e-233	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02944	2.06e-93	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_02945	9.64e-55	-	-	-	S	-	-	-	Helix-turn-helix domain
COGEGGMA_02946	5.25e-149	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_02947	1.07e-157	-	-	-	L	-	-	-	5'-3' exonuclease, N-terminal resolvase-like domain
COGEGGMA_02948	4.45e-71	-	-	-	C	-	-	-	4Fe-4S binding domain
COGEGGMA_02951	0.0	-	-	-	KT	ko:K07814	-	ko00000,ko02022	Psort location Cytoplasmic, score
COGEGGMA_02952	6.82e-30	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_02953	2.18e-85	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_02954	2.67e-29	-	-	-	-	-	-	-	-
COGEGGMA_02955	5.63e-106	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
COGEGGMA_02956	2.03e-250	amiF	3.5.1.49	-	S	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	ko00000,ko00001,ko01000	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide
COGEGGMA_02957	5.47e-151	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_02958	5.67e-24	-	-	-	-	-	-	-	-
COGEGGMA_02959	2.17e-32	-	-	-	-	-	-	-	-
COGEGGMA_02960	5.72e-113	-	-	-	K	-	-	-	Cytoplasmic, score
COGEGGMA_02961	6.16e-90	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02962	5.62e-35	-	-	-	-	-	-	-	-
COGEGGMA_02963	4.33e-16	-	-	-	-	-	-	-	-
COGEGGMA_02964	1.26e-08	-	-	-	-	-	-	-	-
COGEGGMA_02965	1.02e-72	-	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Transcription termination
COGEGGMA_02966	0.0	-	-	-	M	-	-	-	sugar transferase
COGEGGMA_02967	1.63e-187	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase WecB/TagA/CpsF family
COGEGGMA_02968	2.09e-134	rfaG3	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
COGEGGMA_02970	2.13e-29	-	-	-	F	-	-	-	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COGEGGMA_02971	7.49e-73	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
COGEGGMA_02972	1.45e-51	-	-	GT2	S	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
COGEGGMA_02974	1.24e-05	exoQ	-	-	M	ko:K16567	-	ko00000	O-Antigen ligase
COGEGGMA_02975	7.87e-49	-	-	-	M	-	-	-	glycosyl transferase
COGEGGMA_02976	8.29e-169	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
COGEGGMA_02977	3.58e-148	-	-	-	C	-	-	-	LUD domain
COGEGGMA_02978	1.62e-229	-	-	-	K	-	-	-	Cupin domain
COGEGGMA_02979	0.0	-	-	-	V	-	-	-	MATE efflux family protein
COGEGGMA_02980	9.97e-103	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COGEGGMA_02981	2.91e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COGEGGMA_02982	8.15e-108	-	-	-	S	-	-	-	CYTH
COGEGGMA_02983	1.16e-238	-	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
COGEGGMA_02984	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COGEGGMA_02985	0.0	-	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	stage II sporulation protein E
COGEGGMA_02986	1.59e-241	iunH	3.2.2.1	-	F	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
COGEGGMA_02987	5.17e-123	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
COGEGGMA_02988	2.95e-160	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
COGEGGMA_02989	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase family M20/M25/M40
COGEGGMA_02990	1.44e-131	-	-	-	S	-	-	-	carboxylic ester hydrolase activity
COGEGGMA_02991	2.96e-151	-	-	-	-	ko:K07726	-	ko00000,ko03000	-
COGEGGMA_02992	5.72e-200	-	-	-	-	-	-	-	-
COGEGGMA_02993	1.44e-35	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_02994	1.57e-37	-	-	-	-	-	-	-	-
COGEGGMA_02995	1.33e-227	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02996	1.14e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
COGEGGMA_02997	0.0	-	-	-	D	-	-	-	Belongs to the SEDS family
COGEGGMA_02998	1.1e-189	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_02999	2.19e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
COGEGGMA_03000	5.8e-270	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
COGEGGMA_03001	1.12e-24	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03002	6.09e-43	gltT	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
COGEGGMA_03003	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4975)
COGEGGMA_03004	6.61e-193	-	-	-	P	-	-	-	COG COG0395 ABC-type sugar transport system, permease component
COGEGGMA_03005	5.48e-204	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_03006	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COGEGGMA_03007	0.0	-	-	-	KT	-	-	-	Helix-turn-helix domain
COGEGGMA_03008	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Cache domain
COGEGGMA_03009	4.65e-91	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COGEGGMA_03010	3.78e-120	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
COGEGGMA_03013	1.97e-45	-	-	-	KT	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03014	7.82e-134	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
COGEGGMA_03015	3.64e-150	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03016	2.36e-64	-	-	-	-	-	-	-	-
COGEGGMA_03017	1.5e-74	-	-	-	K	-	-	-	Belongs to the sigma-70 factor family
COGEGGMA_03018	1.72e-168	-	-	-	V	-	-	-	Abi-like protein
COGEGGMA_03019	2.08e-10	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
COGEGGMA_03020	1.75e-91	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_03021	1.59e-285	-	-	-	CP	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03022	3.73e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_03023	4.49e-183	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03024	5.3e-111	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_03025	7.11e-201	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_03026	1.95e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
COGEGGMA_03027	3.26e-88	-	-	-	S	-	-	-	Nucleotidyltransferase domain
COGEGGMA_03028	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
COGEGGMA_03029	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COGEGGMA_03030	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
COGEGGMA_03031	2.25e-206	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_03032	8.33e-191	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
COGEGGMA_03033	0.0	-	-	-	S	-	-	-	Beta-L-arabinofuranosidase, GH127
COGEGGMA_03034	0.0	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
COGEGGMA_03035	4.26e-220	-	5.1.3.30, 5.1.3.31	-	G	ko:K18910	-	ko00000,ko01000	Xylose isomerase-like TIM barrel
COGEGGMA_03036	7.84e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	histidinol phosphate phosphatase HisJ family
COGEGGMA_03037	2.84e-240	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Psort location Cytoplasmic, score
COGEGGMA_03038	3.22e-289	pgk	2.7.2.3, 5.3.1.1	-	G	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
COGEGGMA_03039	9.02e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COGEGGMA_03040	6.27e-291	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
COGEGGMA_03041	1.83e-116	-	-	-	K	-	-	-	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COGEGGMA_03042	0.0	-	-	-	S	ko:K07137	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03043	1.15e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_03044	3.32e-56	-	-	-	-	-	-	-	-
COGEGGMA_03045	3.5e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03046	0.0	-	-	-	L	-	-	-	Resolvase, N-terminal domain protein
COGEGGMA_03047	9.96e-82	-	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
COGEGGMA_03048	5.01e-91	-	-	-	K	ko:K03088	-	ko00000,ko03021	Putative ATPase subunit of terminase (gpP-like)
COGEGGMA_03049	6.17e-201	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
COGEGGMA_03050	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COGEGGMA_03051	3.81e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_03052	4.37e-284	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_03053	7.45e-167	-	-	-	T	-	-	-	response regulator receiver
COGEGGMA_03054	1.38e-37	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
COGEGGMA_03055	0.0	-	-	-	M	-	-	-	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COGEGGMA_03056	1.62e-182	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
COGEGGMA_03057	1.41e-102	-	-	-	-	-	-	-	-
COGEGGMA_03058	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03059	2.08e-96	-	-	-	U	-	-	-	PrgI family protein
COGEGGMA_03060	2.79e-189	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03061	1.06e-76	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03062	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
COGEGGMA_03063	4.61e-40	-	-	-	-	-	-	-	-
COGEGGMA_03064	1.39e-198	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03065	1.69e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
COGEGGMA_03066	3.5e-218	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
COGEGGMA_03067	0.0	glpK	2.7.1.30	-	H	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COGEGGMA_03068	3.61e-84	-	-	-	S	-	-	-	NusG domain II
COGEGGMA_03069	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
COGEGGMA_03070	0.0	-	1.12.1.3, 1.6.5.3	-	C	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	hydrogenase large subunit
COGEGGMA_03071	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_03072	4.82e-113	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_03073	1.06e-166	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03074	7.64e-131	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain
COGEGGMA_03075	2.01e-208	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
COGEGGMA_03076	0.0	-	1.3.5.1, 1.3.5.4, 1.3.99.33	-	C	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COGEGGMA_03077	3.15e-163	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
COGEGGMA_03078	1.87e-215	-	-	-	CH	-	-	-	Oxidoreductase FAD-binding domain
COGEGGMA_03079	8.38e-260	-	-	-	C	-	-	-	4Fe-4S dicluster domain
COGEGGMA_03080	9.19e-243	-	-	-	C	-	-	-	4Fe-4S dicluster domain
COGEGGMA_03081	5.15e-109	-	-	-	C	-	-	-	Methyl-viologen-reducing hydrogenase, delta subunit
COGEGGMA_03082	0.0	-	1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6	-	C	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
COGEGGMA_03083	1.89e-91	-	-	-	C	-	-	-	4Fe-4S dicluster domain
COGEGGMA_03084	2.51e-197	-	1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6	-	C	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Cysteine-rich domain
COGEGGMA_03085	2.86e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score 9.98
COGEGGMA_03086	9.38e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
COGEGGMA_03087	1.02e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF4866)
COGEGGMA_03088	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03089	1.29e-28	-	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
COGEGGMA_03090	8.52e-273	sunS	-	-	M	-	-	-	Glycosyl transferase family 2
COGEGGMA_03091	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COGEGGMA_03092	0.0	-	-	-	D	-	-	-	lipolytic protein G-D-S-L family
COGEGGMA_03093	2.51e-56	-	-	-	-	-	-	-	-
COGEGGMA_03094	3.21e-178	-	-	-	M	-	-	-	Glycosyl transferase family 2
COGEGGMA_03095	3.81e-275	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_03096	2.56e-227	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	FecCD transport family
COGEGGMA_03097	2.17e-287	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
COGEGGMA_03098	1.86e-197	-	-	-	M	-	-	-	Cell surface protein
COGEGGMA_03099	2.62e-279	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_03100	2.6e-81	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_03101	3.22e-140	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03102	1.3e-300	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COGEGGMA_03103	1.76e-147	hisG	2.4.2.17	-	H	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
COGEGGMA_03104	1.77e-262	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
COGEGGMA_03105	1.76e-126	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COGEGGMA_03106	6.57e-107	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Psort location CytoplasmicMembrane, score
COGEGGMA_03107	6.51e-247	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.87
COGEGGMA_03108	1.83e-150	-	-	-	-	-	-	-	-
COGEGGMA_03109	0.0	-	-	-	C	-	-	-	UPF0313 protein
COGEGGMA_03110	4.3e-189	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
COGEGGMA_03111	0.0	pepD	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.87
COGEGGMA_03112	6.8e-221	ylbJ	-	-	S	-	-	-	sporulation integral membrane protein YlbJ
COGEGGMA_03113	2.51e-94	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03114	1.66e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COGEGGMA_03115	4.62e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.87
COGEGGMA_03116	1.27e-90	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03117	5.13e-46	sasP	-	-	S	ko:K06421	-	ko00000	COG NOG16862 non supervised orthologous group
COGEGGMA_03118	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
COGEGGMA_03119	1.79e-57	-	-	-	-	-	-	-	-
COGEGGMA_03120	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COGEGGMA_03121	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
COGEGGMA_03122	2.47e-77	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03123	6.24e-39	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
COGEGGMA_03124	2.15e-81	-	-	-	S	-	-	-	Sporulation protein YtfJ (Spore_YtfJ)
COGEGGMA_03125	2.65e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2953)
COGEGGMA_03126	9.69e-66	-	-	-	-	-	-	-	-
COGEGGMA_03127	4.04e-108	apfA	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
COGEGGMA_03128	0.0	pbpA2	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	Psort location CytoplasmicMembrane, score
COGEGGMA_03129	1.68e-310	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03130	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
COGEGGMA_03131	2.16e-84	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COGEGGMA_03132	3.72e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COGEGGMA_03133	9.43e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COGEGGMA_03134	5.72e-195	rnfB	-	-	C	ko:K03616	-	ko00000	F420-non-reducing hydrogenase
COGEGGMA_03135	9.51e-122	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
COGEGGMA_03136	7.1e-162	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
COGEGGMA_03137	8.3e-126	rnfG	-	-	P	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
COGEGGMA_03138	1.75e-227	rnfD	-	-	C	ko:K03614	-	ko00000	Electron transport complex
COGEGGMA_03139	0.0	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
COGEGGMA_03140	6.07e-252	-	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
COGEGGMA_03141	6.93e-154	-	-	-	H	-	-	-	4'-phosphopantetheinyl transferase superfamily
COGEGGMA_03142	2.15e-63	-	-	-	T	-	-	-	STAS domain
COGEGGMA_03143	0.0	-	-	-	Q	ko:K04784,ko:K12240	ko01053,map01053	ko00000,ko00001,ko01004,ko01008	AMP-binding enzyme C-terminal domain
COGEGGMA_03144	0.0	-	-	-	TV	-	-	-	MatE
COGEGGMA_03145	0.0	-	-	-	S	-	-	-	PQQ-like domain
COGEGGMA_03146	7.62e-86	-	-	-	-	-	-	-	-
COGEGGMA_03147	9.55e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COGEGGMA_03148	3.36e-124	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03149	4.8e-313	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	Reverse transcriptase (RNA-dependent DNA polymerase)
COGEGGMA_03150	7.71e-183	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
COGEGGMA_03151	6.5e-306	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_03152	3.91e-60	-	-	-	O	ko:K09935	-	ko00000	Domain of unknown function (DUF1768)
COGEGGMA_03154	4.53e-96	-	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
COGEGGMA_03155	4.6e-170	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
COGEGGMA_03156	0.0	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
COGEGGMA_03157	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
COGEGGMA_03158	7.48e-188	-	-	-	S	-	-	-	Dinitrogenase iron-molybdenum cofactor
COGEGGMA_03159	8.96e-10	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGEGGMA_03160	6.26e-92	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
COGEGGMA_03161	2.44e-219	-	-	-	S	ko:K03453	-	ko00000	Sodium Bile acid symporter family
COGEGGMA_03162	2.24e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Pantoate-beta-alanine ligase
COGEGGMA_03163	1.13e-87	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Aspartate decarboxylase
COGEGGMA_03164	4.34e-22	-	-	-	-	-	-	-	-
COGEGGMA_03165	1.84e-159	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2290)
COGEGGMA_03166	0.0	-	-	-	S	-	-	-	UvrD-like helicase C-terminal domain
COGEGGMA_03167	1.91e-298	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
COGEGGMA_03169	4.94e-76	-	-	-	-	-	-	-	-
COGEGGMA_03170	2.97e-79	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_03171	5.08e-56	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_03172	6.47e-45	-	-	-	-	-	-	-	-
COGEGGMA_03173	0.0	-	-	-	L	-	-	-	Transposase DDE domain
COGEGGMA_03174	1.9e-18	-	-	-	M	-	-	-	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COGEGGMA_03175	2.24e-176	-	-	-	V	-	-	-	HNH nucleases
COGEGGMA_03176	0.0	-	-	-	S	-	-	-	AAA ATPase domain
COGEGGMA_03177	0.0	-	-	-	L	-	-	-	TIGRFAM transposase, IS605 OrfB family
COGEGGMA_03178	0.0	-	-	-	M	-	-	-	self proteolysis
COGEGGMA_03180	1.95e-221	-	-	-	M	-	-	-	NlpC/P60 family
COGEGGMA_03181	5.61e-71	-	-	-	K	-	-	-	sequence-specific DNA binding
COGEGGMA_03182	2.11e-76	-	-	-	-	-	-	-	-
COGEGGMA_03183	8.64e-163	-	-	-	KT	-	-	-	LytTr DNA-binding domain
COGEGGMA_03184	0.0	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_03185	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
COGEGGMA_03186	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_03187	8.07e-116	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
COGEGGMA_03188	4.46e-149	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
COGEGGMA_03189	0.0	ywdH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase
COGEGGMA_03190	1e-166	-	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
COGEGGMA_03191	3.16e-158	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
COGEGGMA_03192	6.27e-142	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
COGEGGMA_03194	6.85e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF4317)
COGEGGMA_03195	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COGEGGMA_03196	0.0	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
COGEGGMA_03197	0.0	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
COGEGGMA_03198	1.42e-270	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
COGEGGMA_03199	5.78e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COGEGGMA_03200	1.89e-95	-	-	-	S	-	-	-	Putative ABC-transporter type IV
COGEGGMA_03201	1.94e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
COGEGGMA_03202	1.09e-100	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.87
COGEGGMA_03203	2.91e-164	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_03204	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_03205	5.31e-69	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03206	1.75e-25	-	-	-	S	-	-	-	Putative tranposon-transfer assisting protein
COGEGGMA_03207	2.58e-163	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_03208	3.54e-177	mutE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_03209	7.73e-176	mutG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	Lantibiotic protection ABC transporter permease subunit, MutG family
COGEGGMA_03210	8.73e-81	-	-	-	-	-	-	-	-
COGEGGMA_03211	1.69e-166	-	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.98
COGEGGMA_03212	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	subtilin biosynthesis sensor protein SpaK
COGEGGMA_03213	6.56e-73	-	-	-	L	-	-	-	Arm DNA-binding domain
COGEGGMA_03214	8.68e-36	-	-	-	-	-	-	-	-
COGEGGMA_03215	3.42e-45	-	-	-	-	-	-	-	-
COGEGGMA_03216	5.32e-48	-	-	-	-	-	-	-	-
COGEGGMA_03217	0.0	pbpC	3.4.16.4	-	M	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein 2'
COGEGGMA_03218	1.92e-284	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03219	2.25e-305	-	-	-	-	-	-	-	-
COGEGGMA_03220	0.0	blaR	-	-	KTV	ko:K02172	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	Psort location CytoplasmicMembrane, score
COGEGGMA_03221	1.93e-79	blaI	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	beta-lactamase (penicillinase) repressor
COGEGGMA_03222	1.64e-98	-	-	-	KT	-	-	-	Psort location Cytoplasmic, score 9.98
COGEGGMA_03223	7.58e-77	-	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
COGEGGMA_03224	1.39e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_03225	1.06e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_03226	4.04e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
COGEGGMA_03227	2.06e-108	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
COGEGGMA_03228	3.41e-299	-	-	-	K	-	-	-	Replication initiation factor
COGEGGMA_03229	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
COGEGGMA_03230	5.65e-136	-	-	-	-	-	-	-	-
COGEGGMA_03231	2.88e-72	-	-	-	L	-	-	-	viral genome integration into host DNA
COGEGGMA_03233	5.06e-234	-	2.1.1.72	-	L	ko:K00571,ko:K07319	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
COGEGGMA_03234	2.32e-196	-	-	-	L	-	-	-	Restriction endonuclease EcoRI
COGEGGMA_03235	4.66e-231	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
COGEGGMA_03236	3.05e-177	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
COGEGGMA_03237	2.63e-53	-	-	-	K	-	-	-	Transcriptional regulator
COGEGGMA_03239	7.74e-111	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_03240	9.78e-68	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
COGEGGMA_03241	5.51e-46	-	-	-	-	-	-	-	-
COGEGGMA_03243	2.2e-175	-	-	-	-	-	-	-	-
COGEGGMA_03244	1.99e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_03245	1.02e-260	-	-	-	-	-	-	-	-
COGEGGMA_03246	3.65e-15	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
COGEGGMA_03247	1.82e-229	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
COGEGGMA_03248	4.18e-60	-	-	-	L	-	-	-	Transposase
COGEGGMA_03249	5.83e-60	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
COGEGGMA_03250	7.84e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03251	2.87e-47	-	-	-	-	-	-	-	-
COGEGGMA_03252	2.88e-39	-	-	-	-	-	-	-	-
COGEGGMA_03253	5.35e-121	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
COGEGGMA_03254	2.57e-272	-	-	-	T	-	-	-	Sh3 type 3 domain protein
COGEGGMA_03255	5.55e-212	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03256	3.55e-279	alaXL	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Threonine alanine tRNA ligase second additional domain protein
COGEGGMA_03257	3.36e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_03258	1.21e-104	-	-	-	-	-	-	-	-
COGEGGMA_03259	5.17e-66	-	-	-	S	-	-	-	Methyltransferase domain
COGEGGMA_03260	3.03e-258	-	-	-	C	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
COGEGGMA_03261	3.34e-92	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ABC transporter
COGEGGMA_03262	3.37e-162	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COGEGGMA_03263	2.32e-194	eutJ	-	-	E	ko:K04024	-	ko00000	Type IV pilus assembly protein PilM;
COGEGGMA_03264	1.95e-118	-	-	-	F	-	-	-	Ureidoglycolate lyase
COGEGGMA_03265	1.05e-95	PaaY	-	-	S	ko:K02617	-	ko00000	Hexapeptide repeat of succinyl-transferase
COGEGGMA_03266	1.21e-59	-	-	-	CQ	-	-	-	BMC
COGEGGMA_03267	1.3e-59	-	-	-	S	-	-	-	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03268	1.81e-147	-	-	-	S	-	-	-	HAD-hyrolase-like
COGEGGMA_03269	0.0	radA	-	-	L	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COGEGGMA_03270	8.12e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03271	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Psort location Cytoplasmic, score 9.98
COGEGGMA_03272	9.51e-81	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
COGEGGMA_03273	9.73e-179	-	-	-	S	-	-	-	SseB protein N-terminal domain
COGEGGMA_03274	1.14e-314	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03275	1.83e-148	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COGEGGMA_03276	4.78e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03277	1.31e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COGEGGMA_03278	0.0	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03279	4.05e-64	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03280	3.03e-106	-	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
COGEGGMA_03281	6.09e-24	-	-	-	-	-	-	-	-
COGEGGMA_03282	2.7e-161	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COGEGGMA_03283	2.17e-213	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
COGEGGMA_03284	2.94e-192	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
COGEGGMA_03285	4.46e-226	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
COGEGGMA_03286	9.71e-317	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COGEGGMA_03287	1.04e-41	-	-	-	K	ko:K03704	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.98
COGEGGMA_03288	7.64e-61	-	-	-	-	-	-	-	-
COGEGGMA_03289	2.51e-197	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03290	4.58e-119	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03291	7.42e-75	-	-	-	KT	-	-	-	Sporulation initiation factor Spo0A C terminal
COGEGGMA_03292	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
COGEGGMA_03293	0.0	-	-	-	M	-	-	-	extracellular matrix structural constituent
COGEGGMA_03294	2.36e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03295	9.4e-192	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03296	5.49e-163	gph	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03297	4.83e-153	maf	-	-	D	ko:K06287	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03298	2.69e-46	-	-	-	-	-	-	-	-
COGEGGMA_03299	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glutaminyl-tRNA synthetase
COGEGGMA_03301	3.32e-135	sigH	-	-	K	ko:K03091	-	ko00000,ko03021	Psort location Cytoplasmic, score 8.87
COGEGGMA_03302	5.22e-173	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COGEGGMA_03303	2.48e-106	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COGEGGMA_03304	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COGEGGMA_03305	7.92e-113	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
COGEGGMA_03306	2.64e-304	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
COGEGGMA_03307	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
COGEGGMA_03308	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	HELICc2
COGEGGMA_03309	0.0	thrA	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COGEGGMA_03310	8.74e-175	tsaA	-	-	S	-	-	-	Uncharacterised protein family UPF0066
COGEGGMA_03311	1.27e-23	-	-	-	-	-	-	-	-
COGEGGMA_03312	0.0	-	-	-	N	-	-	-	endoglucanase-related protein, glucosyl hydrolase family 9 protein
COGEGGMA_03313	1.64e-206	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
COGEGGMA_03314	0.0	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_03315	3.18e-237	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COGEGGMA_03316	1.05e-274	-	-	-	M	-	-	-	Domain of unknown function (DUF4430)
COGEGGMA_03317	0.0	-	-	-	IN	-	-	-	Cysteine-rich secretory protein family
COGEGGMA_03319	0.0	-	-	-	N	-	-	-	Fibronectin type 3 domain
COGEGGMA_03320	2.28e-167	-	-	-	-	-	-	-	-
COGEGGMA_03321	2.51e-55	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
COGEGGMA_03322	2.65e-234	cbiZ	-	-	S	-	-	-	Adenosylcobinamide amidohydrolase
COGEGGMA_03323	0.0	agcS_2	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03324	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
COGEGGMA_03325	1.15e-286	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
COGEGGMA_03326	2.55e-168	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
COGEGGMA_03328	3.62e-289	ttcA	-	-	H	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03329	0.0	rhaB	2.7.1.5	-	H	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
COGEGGMA_03330	2.5e-241	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG COG1879 ABC-type sugar transport system, periplasmic component
COGEGGMA_03331	8.23e-222	-	-	-	P	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components
COGEGGMA_03332	0.0	mglA	3.6.3.17	-	P	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	import. Responsible for energy coupling to the transport system
COGEGGMA_03333	1.5e-228	-	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
COGEGGMA_03334	4.11e-226	-	-	-	G	-	-	-	COG COG1879 ABC-type sugar transport system, periplasmic component
COGEGGMA_03335	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_03336	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain
COGEGGMA_03337	2.27e-103	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	Belongs to the RbsD FucU family
COGEGGMA_03338	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
COGEGGMA_03339	1.26e-212	-	-	-	K	-	-	-	AraC-like ligand binding domain
COGEGGMA_03340	1.07e-220	-	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
COGEGGMA_03341	1.97e-276	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
COGEGGMA_03342	1.27e-173	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03343	7.34e-117	csoS1C	-	-	CQ	-	-	-	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03344	0.0	-	-	-	C	-	-	-	Respiratory-chain NADH dehydrogenase 51 Kd subunit
COGEGGMA_03345	9.07e-52	eutN	-	-	CQ	ko:K04028	-	ko00000	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03346	2.7e-146	pduL	2.3.1.8	-	Q	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
COGEGGMA_03347	1.22e-69	-	-	-	CQ	-	-	-	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03348	1.77e-62	-	-	-	CQ	-	-	-	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03349	7.33e-51	-	-	-	CQ	-	-	-	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein
COGEGGMA_03350	2.19e-67	-	-	-	S	-	-	-	BMC domain
COGEGGMA_03351	3.85e-301	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03352	0.0	eutE	1.2.1.10, 1.2.1.87	-	C	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
COGEGGMA_03353	5.57e-214	fucA	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	L-fuculose phosphate aldolase
COGEGGMA_03354	1.4e-195	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
COGEGGMA_03355	0.0	-	2.3.1.54, 4.3.99.4	-	C	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase
COGEGGMA_03356	4.49e-89	-	-	-	-	-	-	-	-
COGEGGMA_03357	1.23e-178	-	-	-	S	-	-	-	domain, Protein
COGEGGMA_03358	0.0	-	-	-	O	-	-	-	Papain family cysteine protease
COGEGGMA_03359	6.65e-75	-	-	-	S	ko:K07162	-	ko00000	Cysteine-rich small domain
COGEGGMA_03360	3.45e-121	-	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
COGEGGMA_03361	9.74e-98	-	-	-	E	ko:K04031	-	ko00000	BMC domain
COGEGGMA_03362	1.73e-81	-	-	-	E	ko:K04031	-	ko00000	BMC domain
COGEGGMA_03363	2.81e-203	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Psort location Extracellular, score
COGEGGMA_03364	5.63e-254	-	-	-	S	-	-	-	Putative cell wall binding repeat
COGEGGMA_03365	2.43e-240	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
COGEGGMA_03366	2.11e-139	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	DnaJ molecular chaperone homology domain
COGEGGMA_03367	7.27e-207	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03368	1.2e-95	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
COGEGGMA_03369	9.2e-125	-	-	-	S	-	-	-	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family
COGEGGMA_03370	1.42e-289	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
COGEGGMA_03371	1.2e-144	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
COGEGGMA_03372	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
COGEGGMA_03373	9.27e-121	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
COGEGGMA_03374	7.74e-97	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03375	1.44e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_03376	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COGEGGMA_03377	5.44e-104	-	-	-	-	-	-	-	-
COGEGGMA_03378	8.12e-174	-	-	-	S	ko:K01992,ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_03379	3.07e-170	-	-	-	CP	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_03380	2.4e-217	-	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COGEGGMA_03381	1.13e-44	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_03382	8.25e-22	-	-	-	K	ko:K07726	-	ko00000,ko03000	sequence-specific DNA binding
COGEGGMA_03384	6.94e-276	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
COGEGGMA_03386	1.42e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
COGEGGMA_03388	3.56e-183	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
COGEGGMA_03389	1.07e-64	-	-	-	S	-	-	-	Bacterial mobilization protein MobC
COGEGGMA_03390	5.59e-45	-	-	-	S	-	-	-	transposase or invertase
COGEGGMA_03391	1.67e-99	-	-	-	S	-	-	-	HEPN domain
COGEGGMA_03392	1.24e-79	-	-	-	S	-	-	-	Nucleotidyltransferase domain
COGEGGMA_03393	2.56e-190	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	SPFH Band 7 PHB domain protein
COGEGGMA_03394	1.05e-220	hflK	-	-	O	ko:K04088	-	ko00000,ko00002,ko01000	HflC and HflK could encode or regulate a protease
COGEGGMA_03395	7.97e-295	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COGEGGMA_03397	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COGEGGMA_03398	0.0	-	2.7.1.211	-	G	ko:K02756,ko:K02757,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03399	1.24e-199	licT	-	-	K	ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
COGEGGMA_03401	7.55e-69	-	-	-	-	-	-	-	-
COGEGGMA_03402	2.07e-142	-	-	-	S	-	-	-	Protease prsW family
COGEGGMA_03403	3.33e-153	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
COGEGGMA_03404	6.72e-66	-	-	-	-	-	-	-	-
COGEGGMA_03405	1.09e-127	-	-	-	K	-	-	-	Sigma-70, region 4
COGEGGMA_03407	1.38e-75	-	-	-	S	-	-	-	CGGC
COGEGGMA_03408	2.89e-173	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COGEGGMA_03409	5.12e-245	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COGEGGMA_03410	2.96e-246	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
COGEGGMA_03411	8.56e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_03412	2.28e-162	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COGEGGMA_03413	2.55e-21	-	-	-	K	-	-	-	trisaccharide binding
COGEGGMA_03414	7.47e-159	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_03415	2.77e-198	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_03416	6.25e-217	-	-	-	V	ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type multidrug transport system ATPase component
COGEGGMA_03417	5.59e-176	-	-	-	CP	ko:K01992,ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_03418	6.52e-174	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
COGEGGMA_03419	1.98e-89	-	-	-	-	-	-	-	-
COGEGGMA_03420	5.18e-134	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03421	1.62e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_03422	3.72e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1847)
COGEGGMA_03423	2.47e-189	-	-	-	K	-	-	-	Protein of unknown function (DUF1648)
COGEGGMA_03424	6.26e-45	-	-	-	-	-	-	-	-
COGEGGMA_03425	8.31e-104	-	-	-	-	-	-	-	-
COGEGGMA_03426	1.29e-106	-	-	-	-	-	-	-	-
COGEGGMA_03427	6.5e-73	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
COGEGGMA_03428	2.87e-133	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03429	2.4e-30	-	-	-	-	-	-	-	-
COGEGGMA_03430	2.39e-228	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COGEGGMA_03431	8.81e-90	-	-	-	KT	-	-	-	Response regulator of the LytR AlgR family
COGEGGMA_03432	0.0	-	-	-	S	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COGEGGMA_03433	4.13e-166	-	-	-	KT	-	-	-	LytTr DNA-binding domain
COGEGGMA_03434	5.57e-290	-	-	-	T	-	-	-	GHKL domain
COGEGGMA_03435	6.32e-225	-	-	-	-	-	-	-	-
COGEGGMA_03437	0.0	-	-	-	T	-	-	-	diguanylate cyclase
COGEGGMA_03438	3.18e-16	-	-	-	-	-	-	-	-
COGEGGMA_03439	1.34e-205	-	-	-	-	-	-	-	-
COGEGGMA_03440	5.88e-163	-	-	-	P	-	-	-	VTC domain
COGEGGMA_03441	7e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03442	0.0	-	-	-	M	-	-	-	CotH kinase protein
COGEGGMA_03443	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
COGEGGMA_03444	1.88e-242	-	-	-	C	-	-	-	lyase activity
COGEGGMA_03445	2.84e-316	-	-	-	M	-	-	-	Glycosyl transferase family group 2
COGEGGMA_03446	0.0	-	-	-	S	-	-	-	Purple acid Phosphatase, N-terminal domain
COGEGGMA_03447	2.79e-42	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score 8.87
COGEGGMA_03448	5.31e-54	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score 8.87
COGEGGMA_03449	2.19e-33	-	-	-	G	-	-	-	Glycogen debranching enzyme
COGEGGMA_03450	5.39e-96	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
COGEGGMA_03451	7.5e-165	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	TIGRFAM competence protein ComEA helix-hairpin-helix repeat
COGEGGMA_03452	9.41e-164	-	-	-	T	-	-	-	response regulator receiver
COGEGGMA_03453	3.66e-113	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_03454	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.98
COGEGGMA_03455	0.0	fdhA2	1.17.1.11, 1.17.1.9	-	C	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	Molydopterin dinucleotide binding domain
COGEGGMA_03456	0.0	-	-	-	C	-	-	-	domain protein
COGEGGMA_03457	8.95e-293	-	-	-	KT	-	-	-	stage II sporulation protein E
COGEGGMA_03458	7.37e-103	-	-	-	S	-	-	-	MOSC domain
COGEGGMA_03459	1.59e-303	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
COGEGGMA_03460	3.59e-118	mobB	2.7.7.77	-	H	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Molybdopterin-guanine dinucleotide biosynthesis protein
COGEGGMA_03461	1.3e-200	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
COGEGGMA_03462	1.07e-241	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03463	3.21e-110	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
COGEGGMA_03464	3.6e-150	-	-	-	H	-	-	-	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COGEGGMA_03465	7.68e-143	-	-	-	-	-	-	-	-
COGEGGMA_03466	3.22e-115	-	-	-	-	-	-	-	-
COGEGGMA_03467	6.29e-71	-	-	-	S	-	-	-	Bacteriophage holin family
COGEGGMA_03468	4.25e-164	-	-	-	M	-	-	-	RHS repeat-associated core domain
COGEGGMA_03469	1.18e-91	-	-	-	M	-	-	-	RHS repeat-associated core domain
COGEGGMA_03471	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	Psort location CytoplasmicMembrane, score
COGEGGMA_03472	2.53e-214	-	-	-	S	ko:K06298	-	ko00000	Sporulation and spore germination
COGEGGMA_03473	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	DNA internalization-related competence protein ComEC Rec2
COGEGGMA_03474	9.69e-317	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.36
COGEGGMA_03475	2.21e-193	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
COGEGGMA_03476	4.8e-122	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
COGEGGMA_03477	6.83e-224	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
COGEGGMA_03478	3.98e-230	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
COGEGGMA_03479	1.5e-16	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
COGEGGMA_03480	1.16e-210	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COGEGGMA_03481	1.21e-281	spoIIP	-	-	M	ko:K06385	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03482	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COGEGGMA_03483	4.11e-51	-	-	-	-	-	-	-	-
COGEGGMA_03484	4.16e-281	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
COGEGGMA_03485	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COGEGGMA_03486	4.6e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Psort location Cytoplasmic, score
COGEGGMA_03487	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COGEGGMA_03488	6.14e-176	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Psort location Cytoplasmic, score 8.87
COGEGGMA_03489	7.07e-92	-	-	-	-	-	-	-	-
COGEGGMA_03490	2.55e-247	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03491	1.14e-197	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COGEGGMA_03492	1.78e-301	-	-	-	S	-	-	-	YbbR-like protein
COGEGGMA_03493	4.33e-57	-	-	-	G	ko:K11189	-	ko00000,ko02000	Psort location Cytoplasmic, score
COGEGGMA_03494	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
COGEGGMA_03495	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
COGEGGMA_03496	1.73e-70	-	-	-	P	-	-	-	EamA-like transporter family
COGEGGMA_03497	1.84e-76	-	-	-	EG	-	-	-	spore germination
COGEGGMA_03498	3.35e-218	-	2.4.2.53	GT2	M	ko:K10012	ko00520,ko01503,map00520,map01503	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	Glycosyl transferase family 2
COGEGGMA_03499	5.3e-240	-	-	-	M	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
COGEGGMA_03500	0.0	-	-	-	F	-	-	-	ATP-grasp domain
COGEGGMA_03501	1.1e-283	wecE	2.6.1.59	-	E	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
COGEGGMA_03502	6.95e-300	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_03503	1.89e-138	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COGEGGMA_03504	7.18e-193	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
COGEGGMA_03505	3.01e-311	-	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_03506	0.0	-	-	-	H	-	-	-	Methyltransferase domain
COGEGGMA_03507	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
COGEGGMA_03508	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
COGEGGMA_03509	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COGEGGMA_03510	3.38e-292	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COGEGGMA_03511	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family
COGEGGMA_03512	1.52e-238	-	-	-	M	ko:K07011	-	ko00000	Glycosyl transferase family group 2
COGEGGMA_03513	0.0	-	2.7.8.6	-	M	ko:K00996	-	ko00000,ko01000,ko01005	CoA-binding domain
COGEGGMA_03514	8.72e-272	-	-	-	K	-	-	-	COG COG1316 Transcriptional regulator
COGEGGMA_03515	2.24e-238	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	LPS side chain defect rhamnosyl transferase
COGEGGMA_03516	0.0	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin
COGEGGMA_03517	0.0	clpX_1	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COGEGGMA_03518	5.57e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03519	0.0	-	-	-	N	-	-	-	Leucine-rich repeat (LRR) protein
COGEGGMA_03520	3.1e-269	-	-	-	M	-	-	-	Fibronectin type 3 domain
COGEGGMA_03522	3.2e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03523	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COGEGGMA_03524	2.16e-239	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COGEGGMA_03525	1.92e-213	-	-	-	P	ko:K07219	-	ko00000	TIGRFAM DNA binding domain
COGEGGMA_03526	2.67e-39	mopI	-	-	H	ko:K02019	-	ko00000,ko03000	pfam tobe
COGEGGMA_03527	3.36e-180	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, periplasmic molybdate-binding protein
COGEGGMA_03528	3e-156	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdate ABC transporter
COGEGGMA_03529	1.84e-263	modC	3.6.3.29	-	E	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COGEGGMA_03530	1.76e-257	-	-	-	KT	-	-	-	PucR C-terminal helix-turn-helix domain
COGEGGMA_03531	5.53e-265	ugpC_1	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COGEGGMA_03532	3.47e-224	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
COGEGGMA_03533	6.83e-16	-	-	-	K	-	-	-	Helix-turn-helix
COGEGGMA_03534	1.14e-164	-	-	-	K	-	-	-	Response regulator receiver domain protein
COGEGGMA_03535	1.11e-41	-	-	-	K	-	-	-	trisaccharide binding
COGEGGMA_03536	4.76e-84	-	-	-	K	-	-	-	Helix-turn-helix domain
COGEGGMA_03537	5.28e-68	-	-	-	-	-	-	-	-
COGEGGMA_03538	6.81e-82	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_03539	3.29e-277	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03540	7.88e-35	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG COG3505 Type IV secretory pathway, VirD4 components
COGEGGMA_03541	1.76e-232	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03542	3.37e-273	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03543	3.38e-252	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP-glucose 4-epimerase
COGEGGMA_03544	3.24e-104	-	-	-	D	-	-	-	Capsular exopolysaccharide family
COGEGGMA_03545	2.19e-191	-	-	-	-	-	-	-	-
COGEGGMA_03546	8.06e-187	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
COGEGGMA_03547	5.75e-82	-	-	-	-	-	-	-	-
COGEGGMA_03548	2.22e-286	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
COGEGGMA_03549	1.55e-157	ogt	-	-	L	-	-	-	YjbR
COGEGGMA_03550	1.83e-33	-	-	-	-	-	-	-	-
COGEGGMA_03551	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03553	8.66e-46	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
COGEGGMA_03554	4.65e-42	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COGEGGMA_03556	1.55e-25	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03557	1.57e-84	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COGEGGMA_03558	2.63e-44	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
COGEGGMA_03559	2.26e-228	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
COGEGGMA_03560	3.53e-227	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
COGEGGMA_03561	3.79e-121	-	-	-	J	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03562	2.86e-187	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03563	1.53e-39	-	-	-	-	-	-	-	-
COGEGGMA_03564	2.97e-76	-	-	-	K	-	-	-	DeoR-like helix-turn-helix domain
COGEGGMA_03565	1.72e-59	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03566	1.72e-114	-	-	-	C	-	-	-	nitroreductase
COGEGGMA_03567	3.47e-14	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ABC-type nitrate sulfonate bicarbonate transport system ATPase component
COGEGGMA_03568	0.000395	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COGEGGMA_03570	4.16e-106	-	-	-	-	-	-	-	-
COGEGGMA_03571	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolases family 2
COGEGGMA_03572	3.94e-248	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
COGEGGMA_03574	5.88e-132	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_03575	9.73e-230	-	-	-	C	ko:K07079	-	ko00000	4Fe-4S dicluster domain
COGEGGMA_03576	3.66e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COGEGGMA_03577	1.15e-116	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COGEGGMA_03578	4.23e-120	yqeG	-	-	S	ko:K07015	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03579	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
COGEGGMA_03580	0.0	gdhA	1.4.1.3, 1.4.1.4	-	C	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the Glu Leu Phe Val dehydrogenases family
COGEGGMA_03581	4.38e-102	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COGEGGMA_03582	7.57e-61	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03583	3.37e-176	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COGEGGMA_03584	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03585	1.98e-301	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGEGGMA_03586	2.94e-97	-	-	-	IM	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03587	4.96e-316	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGEGGMA_03588	6.7e-271	-	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
COGEGGMA_03589	4.89e-266	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
COGEGGMA_03590	1.71e-265	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
COGEGGMA_03591	1.27e-169	rfbB	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.49
COGEGGMA_03592	2.29e-178	pyrL	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
COGEGGMA_03593	2.1e-185	-	-	-	S	-	-	-	TPM domain
COGEGGMA_03594	9.23e-270	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03595	6.24e-263	-	-	-	S	-	-	-	SPFH domain-Band 7 family
COGEGGMA_03596	1.03e-91	-	-	-	T	-	-	-	Histidine kinase-like ATPase domain
COGEGGMA_03597	2.25e-28	-	-	-	T	-	-	-	STAS domain
COGEGGMA_03598	1.11e-20	-	-	-	T	-	-	-	STAS domain
COGEGGMA_03599	2.31e-95	-	-	-	C	-	-	-	Flavodoxin domain
COGEGGMA_03600	1.6e-126	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
COGEGGMA_03601	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Psort location
COGEGGMA_03602	6.5e-268	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COGEGGMA_03603	1.88e-167	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03604	3.46e-54	ptsH	-	-	G	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03605	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03606	2.75e-213	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COGEGGMA_03607	0.0	agcS	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03608	0.0	hgdC_1	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
COGEGGMA_03609	0.0	-	-	-	E	-	-	-	2-hydroxyglutaryl-CoA dehydratase, D-component
COGEGGMA_03610	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG COG1132 ABC-type multidrug transport system, ATPase and permease components
COGEGGMA_03611	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
COGEGGMA_03612	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COGEGGMA_03613	5.09e-203	-	-	-	S	ko:K06864	-	ko00000	Psort location Cytoplasmic, score 8.87
COGEGGMA_03614	3.69e-188	-	-	-	K	-	-	-	AraC-like ligand binding domain
COGEGGMA_03615	0.0	uidB_2	-	-	G	ko:K03292	-	ko00000	Transporter, major facilitator family protein
COGEGGMA_03616	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
COGEGGMA_03617	3.92e-214	araC_2	-	-	K	ko:K02099	-	ko00000,ko03000	transcriptional regulator AraC family
COGEGGMA_03618	1.28e-132	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_03619	5.1e-123	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_03620	3.38e-17	-	-	-	L	-	-	-	RelB antitoxin
COGEGGMA_03621	9.55e-06	-	-	-	S	ko:K19165	-	ko00000,ko02048	Antitoxin Phd_YefM, type II toxin-antitoxin system
COGEGGMA_03622	1.1e-131	-	-	-	S	-	-	-	Putative restriction endonuclease
COGEGGMA_03623	2.23e-150	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_03624	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
COGEGGMA_03625	1.63e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
COGEGGMA_03626	0.0	-	-	-	L	-	-	-	TIGRFAM transposase, IS605 OrfB family
COGEGGMA_03627	2.93e-102	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
COGEGGMA_03628	0.0	-	-	-	-	-	-	-	-
COGEGGMA_03629	2.19e-106	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
COGEGGMA_03631	0.0	-	-	-	KT	-	-	-	BlaR1 peptidase M56
COGEGGMA_03632	8.02e-84	-	-	-	K	-	-	-	Penicillinase repressor
COGEGGMA_03633	6.58e-173	-	-	-	-	-	-	-	-
COGEGGMA_03634	9.55e-70	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03635	2.19e-08	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03636	1.11e-279	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
COGEGGMA_03637	5.58e-143	-	-	-	-	-	-	-	-
COGEGGMA_03638	1.06e-25	-	-	-	-	-	-	-	-
COGEGGMA_03639	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
COGEGGMA_03640	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
COGEGGMA_03641	1.76e-10	-	-	-	K	-	-	-	Penicillinase repressor
COGEGGMA_03642	2.07e-27	-	-	-	-	-	-	-	-
COGEGGMA_03643	2.44e-213	-	-	-	-	-	-	-	-
COGEGGMA_03644	9.91e-55	-	-	-	S	-	-	-	Transposase IS66 family
COGEGGMA_03645	2.73e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_03647	1.9e-258	-	-	-	-	-	-	-	-
COGEGGMA_03648	1.17e-61	-	-	-	L	-	-	-	PFAM Transposase
COGEGGMA_03649	6.31e-160	-	-	-	-	-	-	-	-
COGEGGMA_03650	3.9e-262	-	-	-	M	-	-	-	COG NOG29868 non supervised orthologous group
COGEGGMA_03651	1.06e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
COGEGGMA_03652	1.6e-161	-	-	-	-	-	-	-	-
COGEGGMA_03653	2.72e-205	-	-	-	-	-	-	-	-
COGEGGMA_03654	0.0	-	-	-	-	-	-	-	-
COGEGGMA_03655	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
COGEGGMA_03656	1.45e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
COGEGGMA_03658	8.23e-217	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
COGEGGMA_03659	2.32e-26	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
COGEGGMA_03660	1.7e-200	-	-	-	T	-	-	-	Histidine kinase
COGEGGMA_03661	2.63e-66	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	substrate-binding protein
COGEGGMA_03662	2.32e-303	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COGEGGMA_03663	2.49e-166	-	-	-	T	-	-	-	cheY-homologous receiver domain
COGEGGMA_03664	2.19e-187	-	-	-	M	-	-	-	Papain-like cysteine protease AvrRpt2
COGEGGMA_03665	3.28e-195	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COGEGGMA_03666	0.0	-	-	-	-	-	-	-	-
COGEGGMA_03667	5.37e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
COGEGGMA_03668	4.32e-94	-	-	-	-	-	-	-	-
COGEGGMA_03669	0.0	-	-	-	S	-	-	-	ErfK YbiS YcfS YnhG
COGEGGMA_03670	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
COGEGGMA_03671	7.22e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
COGEGGMA_03672	6.23e-77	-	-	-	G	-	-	-	Psort location
COGEGGMA_03673	8.04e-257	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
COGEGGMA_03674	1.23e-110	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily