ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IMBHKMNO_00001 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IMBHKMNO_00002 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMBHKMNO_00003 6.1e-40 yazB - - K - - - transcriptional
IMBHKMNO_00004 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMBHKMNO_00005 4.62e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMBHKMNO_00006 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMBHKMNO_00007 2.83e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IMBHKMNO_00008 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IMBHKMNO_00009 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMBHKMNO_00010 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IMBHKMNO_00011 9.74e-199 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IMBHKMNO_00012 3.72e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMBHKMNO_00013 8.14e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMBHKMNO_00014 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMBHKMNO_00015 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IMBHKMNO_00016 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IMBHKMNO_00017 6.66e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IMBHKMNO_00018 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IMBHKMNO_00019 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IMBHKMNO_00022 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IMBHKMNO_00023 1.7e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IMBHKMNO_00024 1.31e-131 yabQ - - S - - - spore cortex biosynthesis protein
IMBHKMNO_00025 5.47e-66 yabP - - S - - - Sporulation protein YabP
IMBHKMNO_00026 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IMBHKMNO_00027 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IMBHKMNO_00028 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_00029 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IMBHKMNO_00030 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMBHKMNO_00031 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
IMBHKMNO_00032 1.95e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IMBHKMNO_00033 6.18e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMBHKMNO_00034 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMBHKMNO_00035 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMBHKMNO_00036 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IMBHKMNO_00037 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IMBHKMNO_00038 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IMBHKMNO_00039 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMBHKMNO_00040 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
IMBHKMNO_00041 5.32e-53 veg - - S - - - protein conserved in bacteria
IMBHKMNO_00042 2.85e-209 yabG - - S ko:K06436 - ko00000 peptidase
IMBHKMNO_00043 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IMBHKMNO_00044 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMBHKMNO_00045 2.49e-310 yabE - - T - - - protein conserved in bacteria
IMBHKMNO_00046 2.05e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IMBHKMNO_00047 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMBHKMNO_00048 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IMBHKMNO_00049 4.93e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMBHKMNO_00050 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IMBHKMNO_00051 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IMBHKMNO_00052 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IMBHKMNO_00053 9e-189 yaaT - - S - - - stage 0 sporulation protein
IMBHKMNO_00054 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IMBHKMNO_00055 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IMBHKMNO_00056 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
IMBHKMNO_00057 4.49e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMBHKMNO_00058 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IMBHKMNO_00059 1.15e-242 yaaN - - P - - - Belongs to the TelA family
IMBHKMNO_00060 2.51e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IMBHKMNO_00061 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IMBHKMNO_00062 2.46e-235 yaaC - - S - - - YaaC-like Protein
IMBHKMNO_00063 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IMBHKMNO_00064 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IMBHKMNO_00065 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMBHKMNO_00066 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMBHKMNO_00067 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMBHKMNO_00068 3.43e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IMBHKMNO_00070 3.06e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IMBHKMNO_00071 1.64e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IMBHKMNO_00072 7.12e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IMBHKMNO_00073 1.75e-129 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IMBHKMNO_00074 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IMBHKMNO_00075 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMBHKMNO_00076 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMBHKMNO_00077 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMBHKMNO_00078 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
IMBHKMNO_00079 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IMBHKMNO_00081 1.17e-97 - - - S - - - Domain of unknown function (DUF2479)
IMBHKMNO_00082 0.0 - - - M - - - Pectate lyase superfamily protein
IMBHKMNO_00083 7.15e-123 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IMBHKMNO_00085 0.0 - - - D - - - Phage tail tape measure protein
IMBHKMNO_00086 4.88e-69 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
IMBHKMNO_00087 4.52e-181 - - - S - - - portal protein
IMBHKMNO_00088 0.000941 - - - - - - - -
IMBHKMNO_00089 1.51e-271 terL - - S - - - Terminase
IMBHKMNO_00090 2e-58 - - - L - - - Terminase, small subunit
IMBHKMNO_00093 5.94e-12 - - - - - - - -
IMBHKMNO_00094 4.71e-10 - - - L ko:K07451 - ko00000,ko01000,ko02048 COG1403 Restriction endonuclease
IMBHKMNO_00102 1.33e-171 - - - S - - - COG0457 FOG TPR repeat
IMBHKMNO_00103 5.57e-227 - - - L - - - Replication protein
IMBHKMNO_00106 1.44e-06 - - - L - - - COG3843 Type IV secretory pathway, VirD2 components (relaxase)
IMBHKMNO_00111 4.07e-15 - - - K - - - Transcriptional regulator
IMBHKMNO_00117 5.57e-207 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IMBHKMNO_00118 5.96e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IMBHKMNO_00119 0.0 - - - M - - - Pectate lyase superfamily protein
IMBHKMNO_00130 6.1e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IMBHKMNO_00131 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
IMBHKMNO_00132 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IMBHKMNO_00133 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMBHKMNO_00134 8.43e-198 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IMBHKMNO_00135 6.18e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMBHKMNO_00136 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IMBHKMNO_00137 1.37e-270 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IMBHKMNO_00138 7.2e-162 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IMBHKMNO_00139 4.48e-156 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IMBHKMNO_00140 8.91e-203 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IMBHKMNO_00141 5.26e-160 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IMBHKMNO_00142 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IMBHKMNO_00143 7.45e-235 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IMBHKMNO_00144 2.59e-312 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IMBHKMNO_00145 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IMBHKMNO_00146 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IMBHKMNO_00147 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IMBHKMNO_00148 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IMBHKMNO_00149 1.26e-100 ytkA - - S - - - YtkA-like
IMBHKMNO_00151 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IMBHKMNO_00152 1.23e-79 ytkC - - S - - - Bacteriophage holin family
IMBHKMNO_00153 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IMBHKMNO_00154 7.52e-174 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IMBHKMNO_00155 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IMBHKMNO_00156 2.51e-236 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IMBHKMNO_00157 1.29e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IMBHKMNO_00158 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IMBHKMNO_00159 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMBHKMNO_00160 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMBHKMNO_00161 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IMBHKMNO_00162 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_00163 3.33e-83 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMBHKMNO_00164 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IMBHKMNO_00165 8.21e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IMBHKMNO_00166 2.12e-184 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
IMBHKMNO_00168 1.26e-136 ytqB - - J - - - Putative rRNA methylase
IMBHKMNO_00169 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IMBHKMNO_00170 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_00171 7.01e-244 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IMBHKMNO_00172 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
IMBHKMNO_00173 5.41e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IMBHKMNO_00174 5.11e-208 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_00175 2.87e-223 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMBHKMNO_00176 1.02e-232 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMBHKMNO_00177 3e-208 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IMBHKMNO_00178 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_00179 9.17e-286 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IMBHKMNO_00180 2.6e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_00181 4.13e-220 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IMBHKMNO_00182 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_00183 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IMBHKMNO_00184 3.8e-163 ywaF - - S - - - Integral membrane protein
IMBHKMNO_00185 1.36e-268 yttB - - EGP - - - Major facilitator superfamily
IMBHKMNO_00186 8.39e-175 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IMBHKMNO_00187 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
IMBHKMNO_00188 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IMBHKMNO_00189 8.6e-69 ytwF - - P - - - Sulfurtransferase
IMBHKMNO_00190 1.39e-110 - - - M - - - Acetyltransferase (GNAT) domain
IMBHKMNO_00191 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IMBHKMNO_00192 2.37e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IMBHKMNO_00193 1.31e-216 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMBHKMNO_00194 3.95e-311 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IMBHKMNO_00195 6.42e-238 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_00196 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IMBHKMNO_00197 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IMBHKMNO_00198 1.02e-296 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IMBHKMNO_00199 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_00200 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IMBHKMNO_00201 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IMBHKMNO_00202 1.1e-164 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IMBHKMNO_00203 7.44e-278 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IMBHKMNO_00204 2.99e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IMBHKMNO_00205 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IMBHKMNO_00206 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IMBHKMNO_00207 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMBHKMNO_00208 3.47e-215 ytlQ - - - - - - -
IMBHKMNO_00209 1.96e-225 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IMBHKMNO_00210 2.93e-199 ytmP - - M - - - Phosphotransferase
IMBHKMNO_00211 3.88e-60 ytzH - - S - - - YtzH-like protein
IMBHKMNO_00212 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IMBHKMNO_00213 3.75e-209 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IMBHKMNO_00214 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IMBHKMNO_00215 9.96e-69 ytzB - - S - - - small secreted protein
IMBHKMNO_00216 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IMBHKMNO_00217 5.77e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IMBHKMNO_00218 5.47e-76 ytpP - - CO - - - Thioredoxin
IMBHKMNO_00219 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
IMBHKMNO_00220 2.43e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMBHKMNO_00221 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IMBHKMNO_00222 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IMBHKMNO_00223 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMBHKMNO_00224 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IMBHKMNO_00225 5.9e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
IMBHKMNO_00226 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IMBHKMNO_00227 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IMBHKMNO_00228 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IMBHKMNO_00229 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IMBHKMNO_00230 3.35e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IMBHKMNO_00231 4.16e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IMBHKMNO_00232 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IMBHKMNO_00233 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IMBHKMNO_00234 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMBHKMNO_00235 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IMBHKMNO_00236 4.95e-161 ygaZ - - E - - - AzlC protein
IMBHKMNO_00237 7.76e-191 - - - K - - - Transcriptional regulator
IMBHKMNO_00238 7.09e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMBHKMNO_00239 2.39e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IMBHKMNO_00241 1.36e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IMBHKMNO_00243 1.11e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMBHKMNO_00249 1.45e-09 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_00250 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMBHKMNO_00251 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMBHKMNO_00252 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IMBHKMNO_00253 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IMBHKMNO_00254 2.41e-141 yttP - - K - - - Transcriptional regulator
IMBHKMNO_00255 3.58e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IMBHKMNO_00256 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMBHKMNO_00257 3.39e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IMBHKMNO_00258 6.74e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IMBHKMNO_00259 1.47e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMBHKMNO_00260 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IMBHKMNO_00261 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IMBHKMNO_00262 0.0 ytcJ - - S - - - amidohydrolase
IMBHKMNO_00263 9.45e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMBHKMNO_00264 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IMBHKMNO_00265 2.77e-114 yteJ - - S - - - RDD family
IMBHKMNO_00266 1.67e-152 ytfI - - S - - - Protein of unknown function (DUF2953)
IMBHKMNO_00267 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
IMBHKMNO_00268 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMBHKMNO_00269 6.15e-234 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IMBHKMNO_00270 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMBHKMNO_00271 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IMBHKMNO_00272 1.75e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IMBHKMNO_00273 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IMBHKMNO_00275 8.38e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_00276 1.39e-164 ytkL - - S - - - Belongs to the UPF0173 family
IMBHKMNO_00277 1.94e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
IMBHKMNO_00278 1.24e-62 ytpI - - S - - - YtpI-like protein
IMBHKMNO_00279 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IMBHKMNO_00280 1e-31 - - - - - - - -
IMBHKMNO_00281 2.64e-114 ytrI - - - - - - -
IMBHKMNO_00282 2.01e-74 ytrH - - S - - - Sporulation protein YtrH
IMBHKMNO_00283 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IMBHKMNO_00284 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IMBHKMNO_00285 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMBHKMNO_00286 6.63e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IMBHKMNO_00287 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IMBHKMNO_00288 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IMBHKMNO_00289 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IMBHKMNO_00290 1.41e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
IMBHKMNO_00291 5.65e-96 ytwI - - S - - - membrane
IMBHKMNO_00292 4.52e-82 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IMBHKMNO_00294 1.48e-176 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IMBHKMNO_00295 3.79e-132 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_00297 2.02e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IMBHKMNO_00298 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IMBHKMNO_00299 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IMBHKMNO_00300 4.82e-166 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_00301 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IMBHKMNO_00302 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMBHKMNO_00303 2.32e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IMBHKMNO_00304 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IMBHKMNO_00305 3.43e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMBHKMNO_00306 1.85e-204 ytbE - - S - - - reductase
IMBHKMNO_00307 1.97e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IMBHKMNO_00308 1.69e-89 ytcD - - K - - - Transcriptional regulator
IMBHKMNO_00309 1.8e-248 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IMBHKMNO_00310 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IMBHKMNO_00311 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMBHKMNO_00312 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IMBHKMNO_00313 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IMBHKMNO_00314 4.64e-142 ytxB - - S - - - SNARE associated Golgi protein
IMBHKMNO_00315 4.88e-198 ytxC - - S - - - YtxC-like family
IMBHKMNO_00316 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMBHKMNO_00317 7.21e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IMBHKMNO_00318 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_00319 1.49e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IMBHKMNO_00320 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
IMBHKMNO_00321 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IMBHKMNO_00322 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMBHKMNO_00323 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IMBHKMNO_00324 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMBHKMNO_00325 1.1e-55 ysdA - - S - - - Membrane
IMBHKMNO_00326 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
IMBHKMNO_00327 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
IMBHKMNO_00328 4.03e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IMBHKMNO_00329 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IMBHKMNO_00330 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IMBHKMNO_00331 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IMBHKMNO_00332 3.06e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IMBHKMNO_00333 7.5e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IMBHKMNO_00334 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IMBHKMNO_00335 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
IMBHKMNO_00336 1.38e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IMBHKMNO_00337 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IMBHKMNO_00338 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IMBHKMNO_00339 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IMBHKMNO_00340 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
IMBHKMNO_00341 5.92e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IMBHKMNO_00342 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IMBHKMNO_00343 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMBHKMNO_00344 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMBHKMNO_00345 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMBHKMNO_00346 1.25e-214 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMBHKMNO_00347 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMBHKMNO_00348 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
IMBHKMNO_00349 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IMBHKMNO_00350 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IMBHKMNO_00351 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
IMBHKMNO_00352 5.46e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
IMBHKMNO_00353 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IMBHKMNO_00354 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_00355 3.52e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IMBHKMNO_00356 5e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IMBHKMNO_00357 1.67e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IMBHKMNO_00358 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IMBHKMNO_00359 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IMBHKMNO_00360 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IMBHKMNO_00361 7.09e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IMBHKMNO_00362 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
IMBHKMNO_00363 7.83e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IMBHKMNO_00364 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IMBHKMNO_00365 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IMBHKMNO_00366 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IMBHKMNO_00367 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_00368 2.18e-96 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_00369 4.68e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IMBHKMNO_00370 4.47e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IMBHKMNO_00371 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMBHKMNO_00372 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMBHKMNO_00373 1.85e-115 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IMBHKMNO_00376 4.15e-71 - - - L - - - Phage integrase family
IMBHKMNO_00378 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IMBHKMNO_00379 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
IMBHKMNO_00380 9.21e-115 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
IMBHKMNO_00381 6.37e-17 res - - L - - - Resolvase, N terminal domain
IMBHKMNO_00382 1.2e-54 res - - L - - - Resolvase, N terminal domain
IMBHKMNO_00385 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IMBHKMNO_00386 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IMBHKMNO_00387 1.12e-243 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMBHKMNO_00388 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMBHKMNO_00389 8.67e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IMBHKMNO_00390 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMBHKMNO_00391 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMBHKMNO_00392 7.83e-240 ysoA - - H - - - Tetratricopeptide repeat
IMBHKMNO_00393 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IMBHKMNO_00394 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMBHKMNO_00395 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IMBHKMNO_00396 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMBHKMNO_00397 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IMBHKMNO_00398 3.93e-114 ysxD - - - - - - -
IMBHKMNO_00399 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IMBHKMNO_00400 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IMBHKMNO_00401 2.57e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IMBHKMNO_00402 3.98e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IMBHKMNO_00403 1.2e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IMBHKMNO_00404 3.8e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IMBHKMNO_00405 2.97e-297 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IMBHKMNO_00406 7.7e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMBHKMNO_00407 1.53e-35 - - - - - - - -
IMBHKMNO_00408 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IMBHKMNO_00409 8.89e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IMBHKMNO_00410 1.81e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IMBHKMNO_00411 1.27e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IMBHKMNO_00412 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IMBHKMNO_00413 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IMBHKMNO_00414 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IMBHKMNO_00415 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IMBHKMNO_00416 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IMBHKMNO_00417 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IMBHKMNO_00418 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IMBHKMNO_00419 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IMBHKMNO_00420 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IMBHKMNO_00421 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IMBHKMNO_00422 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IMBHKMNO_00423 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IMBHKMNO_00424 6.04e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IMBHKMNO_00425 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMBHKMNO_00426 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IMBHKMNO_00427 9.52e-205 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IMBHKMNO_00428 5.63e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IMBHKMNO_00429 6.67e-284 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IMBHKMNO_00430 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IMBHKMNO_00431 5.24e-196 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IMBHKMNO_00432 1.12e-267 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMBHKMNO_00433 1.45e-252 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IMBHKMNO_00434 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IMBHKMNO_00436 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IMBHKMNO_00437 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IMBHKMNO_00438 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IMBHKMNO_00439 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
IMBHKMNO_00440 3.91e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMBHKMNO_00441 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IMBHKMNO_00442 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IMBHKMNO_00443 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
IMBHKMNO_00444 8.28e-143 yrbG - - S - - - membrane
IMBHKMNO_00445 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_00446 1.41e-67 yrzD - - S - - - Post-transcriptional regulator
IMBHKMNO_00447 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMBHKMNO_00448 2.55e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IMBHKMNO_00449 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IMBHKMNO_00450 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IMBHKMNO_00451 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMBHKMNO_00452 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMBHKMNO_00453 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IMBHKMNO_00454 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IMBHKMNO_00457 8.26e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IMBHKMNO_00458 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMBHKMNO_00459 5.63e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IMBHKMNO_00460 2.16e-302 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IMBHKMNO_00461 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_00462 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IMBHKMNO_00463 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IMBHKMNO_00464 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
IMBHKMNO_00465 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IMBHKMNO_00466 2.92e-106 yrrD - - S - - - protein conserved in bacteria
IMBHKMNO_00467 8.4e-42 yrzR - - - - - - -
IMBHKMNO_00468 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
IMBHKMNO_00469 1.87e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMBHKMNO_00470 1.38e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMBHKMNO_00471 1.28e-188 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IMBHKMNO_00472 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IMBHKMNO_00473 3.29e-237 yrrI - - S - - - AI-2E family transporter
IMBHKMNO_00474 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMBHKMNO_00475 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
IMBHKMNO_00476 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMBHKMNO_00477 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
IMBHKMNO_00478 1.15e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMBHKMNO_00479 2.71e-152 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IMBHKMNO_00480 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IMBHKMNO_00481 7.66e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IMBHKMNO_00482 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IMBHKMNO_00483 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IMBHKMNO_00484 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IMBHKMNO_00485 7.87e-100 yrrS - - S - - - Protein of unknown function (DUF1510)
IMBHKMNO_00486 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
IMBHKMNO_00487 4.18e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IMBHKMNO_00488 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMBHKMNO_00489 1.13e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IMBHKMNO_00490 3.09e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IMBHKMNO_00491 3.31e-47 yrhC - - S - - - YrhC-like protein
IMBHKMNO_00492 3.22e-104 yrhD - - S - - - Protein of unknown function (DUF1641)
IMBHKMNO_00493 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IMBHKMNO_00494 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IMBHKMNO_00495 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IMBHKMNO_00496 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IMBHKMNO_00497 9.01e-121 yrhH - - Q - - - methyltransferase
IMBHKMNO_00498 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IMBHKMNO_00499 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IMBHKMNO_00500 2.54e-268 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_00501 5.44e-153 yybE - - K - - - Transcriptional regulator
IMBHKMNO_00502 1.96e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMBHKMNO_00503 6.62e-231 romA - - S - - - Beta-lactamase superfamily domain
IMBHKMNO_00504 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IMBHKMNO_00505 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_00506 2.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IMBHKMNO_00507 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
IMBHKMNO_00508 1.13e-184 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
IMBHKMNO_00509 1.19e-189 supH - - S - - - hydrolase
IMBHKMNO_00511 1.37e-120 - - - S - - - DinB family
IMBHKMNO_00512 1.23e-103 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IMBHKMNO_00513 1.38e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_00514 5.75e-38 - - - K - - - acetyltransferase
IMBHKMNO_00515 1.29e-126 yqaC - - F - - - adenylate kinase activity
IMBHKMNO_00516 3.41e-132 yrkN - - K - - - Acetyltransferase (GNAT) family
IMBHKMNO_00517 1.7e-279 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IMBHKMNO_00518 4.64e-160 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
IMBHKMNO_00519 5.51e-301 yrkQ - - T - - - Histidine kinase
IMBHKMNO_00520 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
IMBHKMNO_00521 7.42e-159 - - - E - - - amino acid
IMBHKMNO_00522 1.27e-132 ywqM - - K - - - Transcriptional regulator
IMBHKMNO_00523 6.02e-190 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IMBHKMNO_00524 2.71e-120 - - - K - - - Transcriptional regulator PadR-like family
IMBHKMNO_00525 5.09e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
IMBHKMNO_00526 3.92e-159 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_00527 4.46e-277 - - - EGP - - - Transmembrane secretion effector
IMBHKMNO_00528 1.69e-137 yqeD - - S - - - SNARE associated Golgi protein
IMBHKMNO_00529 9.45e-180 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IMBHKMNO_00530 7.24e-178 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IMBHKMNO_00532 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IMBHKMNO_00533 1.13e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IMBHKMNO_00534 6.94e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMBHKMNO_00535 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IMBHKMNO_00536 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMBHKMNO_00537 5.62e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IMBHKMNO_00538 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IMBHKMNO_00539 1.39e-177 yqeM - - Q - - - Methyltransferase
IMBHKMNO_00540 2.3e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMBHKMNO_00541 6.9e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IMBHKMNO_00542 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IMBHKMNO_00543 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IMBHKMNO_00544 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IMBHKMNO_00545 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IMBHKMNO_00546 8.4e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IMBHKMNO_00547 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IMBHKMNO_00548 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
IMBHKMNO_00549 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IMBHKMNO_00550 2.04e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IMBHKMNO_00551 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IMBHKMNO_00552 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMBHKMNO_00553 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IMBHKMNO_00554 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IMBHKMNO_00555 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IMBHKMNO_00556 1.75e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IMBHKMNO_00557 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IMBHKMNO_00558 2.38e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IMBHKMNO_00559 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IMBHKMNO_00560 3.19e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IMBHKMNO_00561 3.83e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IMBHKMNO_00562 4.78e-177 yqfA - - S - - - UPF0365 protein
IMBHKMNO_00563 2.97e-84 yqfB - - - - - - -
IMBHKMNO_00564 3.57e-61 yqfC - - S - - - sporulation protein YqfC
IMBHKMNO_00565 2.15e-281 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IMBHKMNO_00566 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IMBHKMNO_00567 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IMBHKMNO_00568 4.82e-103 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMBHKMNO_00569 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IMBHKMNO_00570 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IMBHKMNO_00571 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMBHKMNO_00572 6e-24 - - - S - - - YqzL-like protein
IMBHKMNO_00573 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IMBHKMNO_00574 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IMBHKMNO_00575 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IMBHKMNO_00576 5.89e-145 ccpN - - K - - - CBS domain
IMBHKMNO_00577 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IMBHKMNO_00578 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IMBHKMNO_00579 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IMBHKMNO_00580 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IMBHKMNO_00581 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IMBHKMNO_00582 2.01e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IMBHKMNO_00583 8.87e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMBHKMNO_00584 2.04e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMBHKMNO_00585 4.16e-89 yqfQ - - S - - - YqfQ-like protein
IMBHKMNO_00586 6.06e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IMBHKMNO_00587 4.94e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMBHKMNO_00588 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IMBHKMNO_00589 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_00590 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IMBHKMNO_00591 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IMBHKMNO_00592 3.34e-80 yqfX - - S - - - membrane
IMBHKMNO_00593 1.39e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMBHKMNO_00594 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
IMBHKMNO_00595 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
IMBHKMNO_00596 2.76e-99 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IMBHKMNO_00597 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IMBHKMNO_00598 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IMBHKMNO_00599 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IMBHKMNO_00600 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IMBHKMNO_00601 3.53e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IMBHKMNO_00602 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IMBHKMNO_00603 2.39e-185 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMBHKMNO_00604 1.34e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMBHKMNO_00605 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMBHKMNO_00606 3.42e-68 yqzD - - - - - - -
IMBHKMNO_00607 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IMBHKMNO_00608 3.66e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMBHKMNO_00609 5.38e-11 yqgO - - - - - - -
IMBHKMNO_00610 1.79e-276 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IMBHKMNO_00611 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
IMBHKMNO_00612 4.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IMBHKMNO_00613 1.24e-284 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IMBHKMNO_00614 2.2e-255 yqgU - - - - - - -
IMBHKMNO_00615 2.99e-65 dglA - - S - - - Thiamine-binding protein
IMBHKMNO_00616 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
IMBHKMNO_00617 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IMBHKMNO_00618 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IMBHKMNO_00619 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IMBHKMNO_00621 2.39e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IMBHKMNO_00622 3.76e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IMBHKMNO_00623 4.53e-239 yqxL - - P - - - Mg2 transporter protein
IMBHKMNO_00624 5.46e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMBHKMNO_00625 1.97e-234 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IMBHKMNO_00626 5.22e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IMBHKMNO_00627 1.32e-92 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
IMBHKMNO_00628 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IMBHKMNO_00629 1.9e-86 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IMBHKMNO_00630 4.03e-82 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IMBHKMNO_00631 2e-36 yqzE - - S - - - YqzE-like protein
IMBHKMNO_00632 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
IMBHKMNO_00633 6.62e-156 yqxM - - - ko:K19433 - ko00000 -
IMBHKMNO_00634 1.27e-100 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IMBHKMNO_00635 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IMBHKMNO_00636 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IMBHKMNO_00637 1.11e-30 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IMBHKMNO_00638 2.15e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IMBHKMNO_00639 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IMBHKMNO_00640 1.11e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IMBHKMNO_00641 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMBHKMNO_00642 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMBHKMNO_00643 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IMBHKMNO_00644 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IMBHKMNO_00645 2.3e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IMBHKMNO_00646 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IMBHKMNO_00647 7.65e-83 yqhP - - - - - - -
IMBHKMNO_00648 1.04e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
IMBHKMNO_00649 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
IMBHKMNO_00650 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IMBHKMNO_00651 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMBHKMNO_00652 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IMBHKMNO_00653 3.12e-221 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IMBHKMNO_00654 1.7e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IMBHKMNO_00655 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IMBHKMNO_00656 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IMBHKMNO_00657 4.29e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IMBHKMNO_00658 4.27e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IMBHKMNO_00659 7.03e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IMBHKMNO_00660 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IMBHKMNO_00661 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IMBHKMNO_00662 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IMBHKMNO_00663 1.36e-87 yqhY - - S - - - protein conserved in bacteria
IMBHKMNO_00664 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMBHKMNO_00665 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMBHKMNO_00666 1.43e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMBHKMNO_00667 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMBHKMNO_00668 5.49e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IMBHKMNO_00669 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMBHKMNO_00670 1.02e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IMBHKMNO_00671 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IMBHKMNO_00672 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IMBHKMNO_00673 5.12e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IMBHKMNO_00674 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IMBHKMNO_00675 1.63e-238 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMBHKMNO_00676 2.36e-17 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMBHKMNO_00679 3.37e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IMBHKMNO_00681 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
IMBHKMNO_00682 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
IMBHKMNO_00684 6.87e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IMBHKMNO_00685 1.56e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IMBHKMNO_00686 1.95e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IMBHKMNO_00687 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IMBHKMNO_00688 7.19e-260 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IMBHKMNO_00689 3.07e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IMBHKMNO_00690 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IMBHKMNO_00691 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IMBHKMNO_00692 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
IMBHKMNO_00693 0.0 bkdR - - KT - - - Transcriptional regulator
IMBHKMNO_00694 3.37e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IMBHKMNO_00695 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IMBHKMNO_00696 1.2e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IMBHKMNO_00697 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IMBHKMNO_00698 7.89e-222 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IMBHKMNO_00699 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IMBHKMNO_00700 5.1e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMBHKMNO_00701 6.05e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IMBHKMNO_00702 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
IMBHKMNO_00703 3.37e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IMBHKMNO_00704 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IMBHKMNO_00705 6.07e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IMBHKMNO_00706 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IMBHKMNO_00707 2.61e-123 yqjB - - S - - - protein conserved in bacteria
IMBHKMNO_00709 3.82e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IMBHKMNO_00710 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IMBHKMNO_00711 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IMBHKMNO_00712 4.13e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMBHKMNO_00713 1.3e-34 yqzJ - - - - - - -
IMBHKMNO_00714 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMBHKMNO_00715 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMBHKMNO_00716 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMBHKMNO_00717 1.95e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IMBHKMNO_00718 9.1e-189 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMBHKMNO_00719 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IMBHKMNO_00720 1.58e-66 - - - S - - - GlpM protein
IMBHKMNO_00721 1.36e-212 - - - K - - - LysR substrate binding domain
IMBHKMNO_00722 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IMBHKMNO_00723 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_00726 3.89e-314 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IMBHKMNO_00727 1.32e-166 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IMBHKMNO_00728 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00729 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00730 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00731 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00732 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00733 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_00734 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IMBHKMNO_00735 1.98e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IMBHKMNO_00736 3.2e-305 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IMBHKMNO_00737 4.14e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IMBHKMNO_00738 1.95e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMBHKMNO_00739 3.11e-220 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IMBHKMNO_00740 3.96e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_00741 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IMBHKMNO_00742 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IMBHKMNO_00743 2.2e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_00745 6.84e-237 yueF - - S - - - transporter activity
IMBHKMNO_00747 1.12e-76 - - - S - - - YolD-like protein
IMBHKMNO_00748 2.31e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMBHKMNO_00749 1.15e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IMBHKMNO_00750 5.96e-81 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IMBHKMNO_00751 8.7e-225 yqkA - - K - - - GrpB protein
IMBHKMNO_00752 2.2e-79 yqkB - - S - - - Belongs to the HesB IscA family
IMBHKMNO_00753 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
IMBHKMNO_00754 2.02e-226 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IMBHKMNO_00755 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
IMBHKMNO_00756 5.35e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IMBHKMNO_00757 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
IMBHKMNO_00758 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IMBHKMNO_00759 1.45e-280 yqxK - - L - - - DNA helicase
IMBHKMNO_00760 1.15e-75 ansR - - K - - - Transcriptional regulator
IMBHKMNO_00761 5.31e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IMBHKMNO_00762 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IMBHKMNO_00763 2.4e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IMBHKMNO_00764 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IMBHKMNO_00765 1.96e-30 - - - - - - - -
IMBHKMNO_00766 4.38e-47 yqkK - - - - - - -
IMBHKMNO_00767 1.01e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IMBHKMNO_00768 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IMBHKMNO_00769 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
IMBHKMNO_00770 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IMBHKMNO_00771 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMBHKMNO_00772 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMBHKMNO_00773 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IMBHKMNO_00774 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IMBHKMNO_00775 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IMBHKMNO_00776 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_00777 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IMBHKMNO_00778 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IMBHKMNO_00779 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IMBHKMNO_00780 3.34e-243 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IMBHKMNO_00781 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IMBHKMNO_00782 5.32e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
IMBHKMNO_00783 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IMBHKMNO_00784 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IMBHKMNO_00785 2.57e-198 ypuA - - S - - - Secreted protein
IMBHKMNO_00786 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMBHKMNO_00787 2.75e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
IMBHKMNO_00788 8.95e-129 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IMBHKMNO_00789 2.01e-70 ypuD - - - - - - -
IMBHKMNO_00790 1.53e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMBHKMNO_00791 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IMBHKMNO_00792 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMBHKMNO_00793 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IMBHKMNO_00794 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMBHKMNO_00795 1.35e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IMBHKMNO_00797 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMBHKMNO_00798 9.15e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMBHKMNO_00799 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
IMBHKMNO_00800 4.63e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IMBHKMNO_00801 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IMBHKMNO_00802 2.58e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IMBHKMNO_00803 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IMBHKMNO_00804 1.24e-127 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IMBHKMNO_00805 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IMBHKMNO_00806 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IMBHKMNO_00807 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_00808 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_00809 2.64e-134 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_00810 9.73e-255 rsiX - - - - - - -
IMBHKMNO_00811 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMBHKMNO_00812 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMBHKMNO_00813 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IMBHKMNO_00814 3.37e-250 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IMBHKMNO_00815 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IMBHKMNO_00816 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IMBHKMNO_00817 5.85e-124 ypbE - - M - - - Lysin motif
IMBHKMNO_00818 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
IMBHKMNO_00819 1.9e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IMBHKMNO_00820 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IMBHKMNO_00821 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IMBHKMNO_00822 5.3e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IMBHKMNO_00823 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IMBHKMNO_00824 3.77e-213 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IMBHKMNO_00825 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IMBHKMNO_00826 5e-79 ypfA - - M - - - Flagellar protein YcgR
IMBHKMNO_00827 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
IMBHKMNO_00828 1.94e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IMBHKMNO_00829 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IMBHKMNO_00830 1.33e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IMBHKMNO_00831 1.87e-12 - - - S - - - YpzI-like protein
IMBHKMNO_00832 6.19e-136 yphA - - - - - - -
IMBHKMNO_00833 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IMBHKMNO_00834 4.05e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IMBHKMNO_00835 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
IMBHKMNO_00836 4.83e-173 yphF - - - - - - -
IMBHKMNO_00837 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IMBHKMNO_00838 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMBHKMNO_00839 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IMBHKMNO_00840 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IMBHKMNO_00841 1.33e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IMBHKMNO_00842 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IMBHKMNO_00843 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IMBHKMNO_00844 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IMBHKMNO_00845 3.32e-180 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IMBHKMNO_00846 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMBHKMNO_00847 1.11e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMBHKMNO_00848 5.92e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IMBHKMNO_00849 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMBHKMNO_00850 2.37e-211 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMBHKMNO_00851 7.06e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IMBHKMNO_00852 5.03e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IMBHKMNO_00853 1.73e-290 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IMBHKMNO_00854 4.65e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IMBHKMNO_00855 1.44e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMBHKMNO_00856 8.4e-259 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IMBHKMNO_00857 1.35e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IMBHKMNO_00858 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
IMBHKMNO_00859 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
IMBHKMNO_00860 7.88e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
IMBHKMNO_00861 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IMBHKMNO_00862 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IMBHKMNO_00863 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IMBHKMNO_00864 1.2e-132 ypjA - - S - - - membrane
IMBHKMNO_00865 9.73e-181 ypjB - - S - - - sporulation protein
IMBHKMNO_00866 7.86e-287 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IMBHKMNO_00867 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_00868 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IMBHKMNO_00869 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IMBHKMNO_00870 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IMBHKMNO_00871 2.59e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IMBHKMNO_00872 3.63e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IMBHKMNO_00873 8.77e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IMBHKMNO_00874 1.5e-228 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IMBHKMNO_00875 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IMBHKMNO_00876 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMBHKMNO_00877 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IMBHKMNO_00878 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IMBHKMNO_00879 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IMBHKMNO_00880 3.93e-104 ypmB - - S - - - protein conserved in bacteria
IMBHKMNO_00881 1.2e-282 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IMBHKMNO_00882 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IMBHKMNO_00883 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IMBHKMNO_00884 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMBHKMNO_00885 1.8e-119 ypoC - - - - - - -
IMBHKMNO_00886 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMBHKMNO_00887 2.54e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IMBHKMNO_00888 1.58e-236 yppC - - S - - - Protein of unknown function (DUF2515)
IMBHKMNO_00889 0.000542 - - - - ko:K06430 - ko00000 -
IMBHKMNO_00893 9.16e-75 yppG - - S - - - YppG-like protein
IMBHKMNO_00894 1.85e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IMBHKMNO_00895 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IMBHKMNO_00896 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IMBHKMNO_00897 1.91e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IMBHKMNO_00898 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
IMBHKMNO_00899 1.09e-127 ypsA - - S - - - Belongs to the UPF0398 family
IMBHKMNO_00900 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IMBHKMNO_00901 6.65e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IMBHKMNO_00902 6.91e-31 - - - S - - - YpzG-like protein
IMBHKMNO_00904 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IMBHKMNO_00905 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IMBHKMNO_00906 4.04e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IMBHKMNO_00907 4.16e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
IMBHKMNO_00908 1.04e-174 - - - L - - - Belongs to the 'phage' integrase family
IMBHKMNO_00909 1.33e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
IMBHKMNO_00910 3.79e-45 - - - - - - - -
IMBHKMNO_00911 7.2e-50 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
IMBHKMNO_00912 3.41e-112 - - - - - - - -
IMBHKMNO_00916 7.54e-126 - - - - - - - -
IMBHKMNO_00917 6e-79 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
IMBHKMNO_00919 4.83e-99 yqaL - - L - - - DnaD domain protein
IMBHKMNO_00920 3.33e-151 yqaM - - L - - - IstB-like ATP binding protein
IMBHKMNO_00922 2.64e-77 rusA - - L - - - Endodeoxyribonuclease RusA
IMBHKMNO_00924 1.85e-29 yqaO - - S - - - Phage-like element PBSX protein XtrA
IMBHKMNO_00926 7.46e-116 - - - - - - - -
IMBHKMNO_00927 1.88e-204 - - - K - - - Pfam:DUF955
IMBHKMNO_00928 1.19e-87 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IMBHKMNO_00930 1.74e-17 - - - K - - - Transcriptional regulator
IMBHKMNO_00931 2.49e-118 - - - - - - - -
IMBHKMNO_00935 1.42e-99 - - - L - - - phage terminase small subunit
IMBHKMNO_00936 0.0 - - - S - - - Terminase
IMBHKMNO_00937 1.74e-216 - - - S - - - Phage portal protein
IMBHKMNO_00938 9.69e-105 - - - S - - - peptidase activity
IMBHKMNO_00939 2.34e-193 - - - S - - - capsid protein
IMBHKMNO_00940 1.78e-35 - - - - - - - -
IMBHKMNO_00941 1.2e-51 - - - S - - - Phage gp6-like head-tail connector protein
IMBHKMNO_00942 1.34e-54 - - - S - - - Phage head-tail joining protein
IMBHKMNO_00943 8.97e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IMBHKMNO_00945 9.78e-105 - - - S - - - Phage tail tube protein
IMBHKMNO_00946 6.81e-06 - - - - - - - -
IMBHKMNO_00947 0.0 - - - D - - - phage tail tape measure protein
IMBHKMNO_00948 1.08e-131 - - - S - - - Phage tail protein
IMBHKMNO_00949 6.2e-286 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IMBHKMNO_00950 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
IMBHKMNO_00951 2.68e-121 - - - - - - - -
IMBHKMNO_00952 0.000543 - - - - - - - -
IMBHKMNO_00953 2.4e-07 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
IMBHKMNO_00954 5.3e-75 - - - S - - - Pfam:Phage_holin_4_1
IMBHKMNO_00955 6.09e-87 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
IMBHKMNO_00958 4.42e-104 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IMBHKMNO_00960 9.6e-38 - - - K - - - Helix-turn-helix domain
IMBHKMNO_00961 2.99e-128 yrdC - - Q - - - Isochorismatase family
IMBHKMNO_00962 8.58e-09 - - - S - - - Bacillus cereus group antimicrobial protein
IMBHKMNO_00963 6.1e-64 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
IMBHKMNO_00964 2.52e-136 - - - J - - - Acetyltransferase (GNAT) domain
IMBHKMNO_00965 1.04e-267 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IMBHKMNO_00966 3.46e-115 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IMBHKMNO_00967 0.0 ypbR - - S - - - Dynamin family
IMBHKMNO_00968 7.03e-53 ypbS - - S - - - Protein of unknown function (DUF2533)
IMBHKMNO_00969 2.08e-11 - - - - - - - -
IMBHKMNO_00970 1.36e-209 ypcP - - L - - - 5'3' exonuclease
IMBHKMNO_00972 1.22e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IMBHKMNO_00973 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMBHKMNO_00974 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IMBHKMNO_00975 6.59e-40 ypeQ - - S - - - Zinc-finger
IMBHKMNO_00976 6.52e-49 - - - S - - - Protein of unknown function (DUF2564)
IMBHKMNO_00977 1.27e-17 degR - - - - - - -
IMBHKMNO_00978 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IMBHKMNO_00979 1.82e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IMBHKMNO_00980 6.6e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMBHKMNO_00981 1.13e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IMBHKMNO_00982 7.66e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IMBHKMNO_00983 1.56e-201 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IMBHKMNO_00984 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IMBHKMNO_00985 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
IMBHKMNO_00986 1.42e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IMBHKMNO_00987 6.48e-148 ypjP - - S - - - YpjP-like protein
IMBHKMNO_00988 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IMBHKMNO_00989 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMBHKMNO_00990 6.97e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IMBHKMNO_00991 3.69e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IMBHKMNO_00992 3e-226 yplP - - K - - - Transcriptional regulator
IMBHKMNO_00993 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMBHKMNO_00994 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
IMBHKMNO_00995 1.21e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IMBHKMNO_00996 2.58e-176 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IMBHKMNO_00997 5.59e-126 ypmS - - S - - - protein conserved in bacteria
IMBHKMNO_00998 9.6e-89 ypoP - - K - - - transcriptional
IMBHKMNO_00999 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMBHKMNO_01000 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IMBHKMNO_01001 7.81e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IMBHKMNO_01002 1.76e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IMBHKMNO_01003 3.03e-229 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IMBHKMNO_01004 1.73e-87 cgeA - - - ko:K06319 - ko00000 -
IMBHKMNO_01005 8.14e-63 cgeC - - - ko:K06321 - ko00000 -
IMBHKMNO_01006 9.83e-317 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IMBHKMNO_01007 5.71e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IMBHKMNO_01009 3.4e-83 - - - L - - - Bacterial transcription activator, effector binding domain
IMBHKMNO_01010 3.56e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMBHKMNO_01011 2.8e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMBHKMNO_01012 1.09e-158 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IMBHKMNO_01013 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IMBHKMNO_01014 1.91e-201 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IMBHKMNO_01015 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IMBHKMNO_01016 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
IMBHKMNO_01017 1e-47 yozE - - S - - - Belongs to the UPF0346 family
IMBHKMNO_01018 7.75e-161 yodN - - - - - - -
IMBHKMNO_01020 9.77e-34 yozD - - S - - - YozD-like protein
IMBHKMNO_01021 5.04e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IMBHKMNO_01022 1.16e-72 yodL - - S - - - YodL-like
IMBHKMNO_01024 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IMBHKMNO_01025 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IMBHKMNO_01026 1.68e-50 yodI - - - - - - -
IMBHKMNO_01027 1.24e-165 yodH - - Q - - - Methyltransferase
IMBHKMNO_01028 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IMBHKMNO_01029 8.67e-170 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_01030 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMBHKMNO_01031 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IMBHKMNO_01032 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMBHKMNO_01033 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
IMBHKMNO_01034 5.17e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IMBHKMNO_01035 1.46e-141 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IMBHKMNO_01036 1.35e-138 yodC - - C - - - nitroreductase
IMBHKMNO_01037 2.42e-74 yodB - - K - - - transcriptional
IMBHKMNO_01038 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IMBHKMNO_01039 2.59e-89 iolK - - S - - - tautomerase
IMBHKMNO_01041 4.68e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IMBHKMNO_01042 1.03e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IMBHKMNO_01043 1.05e-30 - - - - - - - -
IMBHKMNO_01044 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
IMBHKMNO_01045 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IMBHKMNO_01046 3.39e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IMBHKMNO_01047 2.79e-309 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IMBHKMNO_01049 1.11e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMBHKMNO_01050 1.36e-284 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IMBHKMNO_01051 3.94e-291 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IMBHKMNO_01052 2.55e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMBHKMNO_01053 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IMBHKMNO_01054 0.0 yojO - - P - - - Von Willebrand factor
IMBHKMNO_01055 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IMBHKMNO_01056 2.36e-259 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IMBHKMNO_01057 3.69e-179 - - - S - - - Metallo-beta-lactamase superfamily
IMBHKMNO_01058 9.46e-215 yocS - - S ko:K03453 - ko00000 -transporter
IMBHKMNO_01059 2.93e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IMBHKMNO_01060 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IMBHKMNO_01061 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IMBHKMNO_01062 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMBHKMNO_01063 4.69e-43 yozC - - - - - - -
IMBHKMNO_01065 5.32e-75 yozO - - S - - - Bacterial PH domain
IMBHKMNO_01066 6.36e-50 yocN - - - - - - -
IMBHKMNO_01067 5.58e-59 yozN - - - - - - -
IMBHKMNO_01068 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IMBHKMNO_01069 3.51e-13 yocN - - - - - - -
IMBHKMNO_01070 1.92e-13 yocL - - - - - - -
IMBHKMNO_01071 7.44e-78 yocK - - T - - - general stress protein
IMBHKMNO_01073 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMBHKMNO_01074 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IMBHKMNO_01075 2.42e-159 yocH - - M - - - COG1388 FOG LysM repeat
IMBHKMNO_01077 3.67e-135 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IMBHKMNO_01078 1.22e-86 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IMBHKMNO_01079 1.6e-123 yocC - - - - - - -
IMBHKMNO_01080 1.43e-180 - - - J - - - Protein required for attachment to host cells
IMBHKMNO_01081 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
IMBHKMNO_01082 2.31e-155 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IMBHKMNO_01083 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IMBHKMNO_01084 3.86e-119 yobW - - - - - - -
IMBHKMNO_01085 1.15e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IMBHKMNO_01086 9.22e-123 yobS - - K - - - Transcriptional regulator
IMBHKMNO_01087 1.24e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IMBHKMNO_01088 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IMBHKMNO_01089 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IMBHKMNO_01090 1.3e-100 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IMBHKMNO_01091 2.42e-59 - - - - - - - -
IMBHKMNO_01092 9.42e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_01094 7.35e-35 yoaF - - - - - - -
IMBHKMNO_01095 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMBHKMNO_01096 2.1e-246 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMBHKMNO_01097 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IMBHKMNO_01098 2.21e-261 yoaB - - EGP - - - the major facilitator superfamily
IMBHKMNO_01099 2.48e-175 yoxB - - - - - - -
IMBHKMNO_01100 1.39e-55 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMBHKMNO_01101 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01102 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IMBHKMNO_01103 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMBHKMNO_01104 1.15e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMBHKMNO_01105 1.4e-203 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_01106 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IMBHKMNO_01107 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IMBHKMNO_01108 5.11e-30 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IMBHKMNO_01109 3e-22 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IMBHKMNO_01110 8.44e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IMBHKMNO_01111 2.23e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_01112 5.22e-18 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMBHKMNO_01113 3.29e-67 - - - K - - - Helix-turn-helix domain
IMBHKMNO_01114 4.59e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
IMBHKMNO_01115 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IMBHKMNO_01116 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
IMBHKMNO_01117 3.97e-125 - - - L - - - Integrase
IMBHKMNO_01119 4.47e-126 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IMBHKMNO_01120 7.44e-312 yoeA - - V - - - MATE efflux family protein
IMBHKMNO_01121 4.05e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IMBHKMNO_01122 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IMBHKMNO_01123 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01124 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01125 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01126 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01127 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
IMBHKMNO_01128 6.82e-85 yngL - - S - - - Protein of unknown function (DUF1360)
IMBHKMNO_01129 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IMBHKMNO_01130 3.61e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IMBHKMNO_01131 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IMBHKMNO_01132 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IMBHKMNO_01133 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IMBHKMNO_01134 3.48e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IMBHKMNO_01135 2.48e-178 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IMBHKMNO_01136 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IMBHKMNO_01137 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
IMBHKMNO_01138 8.78e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IMBHKMNO_01139 1.31e-94 yngA - - S - - - membrane
IMBHKMNO_01140 5.24e-185 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IMBHKMNO_01141 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IMBHKMNO_01142 1.08e-270 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IMBHKMNO_01143 3.54e-165 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IMBHKMNO_01144 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IMBHKMNO_01145 2.94e-281 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IMBHKMNO_01146 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IMBHKMNO_01147 5.16e-161 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMBHKMNO_01148 1.51e-155 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IMBHKMNO_01149 4.1e-178 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IMBHKMNO_01150 9.43e-279 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_01151 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01152 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01153 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01154 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IMBHKMNO_01155 5.9e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IMBHKMNO_01156 1.27e-162 - - - T - - - Transcriptional regulatory protein, C terminal
IMBHKMNO_01157 5.91e-313 - - - T - - - Histidine kinase
IMBHKMNO_01158 3.64e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
IMBHKMNO_01159 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IMBHKMNO_01160 1.01e-270 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
IMBHKMNO_01162 0.0 yndJ - - S - - - YndJ-like protein
IMBHKMNO_01163 3.51e-96 - - - S - - - Domain of unknown function (DUF4166)
IMBHKMNO_01164 4.7e-198 yndG - - S - - - DoxX-like family
IMBHKMNO_01165 4.57e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
IMBHKMNO_01166 1.23e-231 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
IMBHKMNO_01167 2.49e-192 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01168 1.61e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IMBHKMNO_01169 3.05e-146 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IMBHKMNO_01170 1.17e-98 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IMBHKMNO_01171 3.03e-121 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IMBHKMNO_01172 1.83e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IMBHKMNO_01173 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IMBHKMNO_01174 1.82e-63 ynfC - - - - - - -
IMBHKMNO_01175 3.14e-19 - - - - - - - -
IMBHKMNO_01176 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMBHKMNO_01177 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMBHKMNO_01178 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IMBHKMNO_01179 1.83e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IMBHKMNO_01180 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
IMBHKMNO_01181 4.68e-71 yneQ - - - - - - -
IMBHKMNO_01182 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IMBHKMNO_01183 4.24e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IMBHKMNO_01185 9.94e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMBHKMNO_01186 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMBHKMNO_01187 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IMBHKMNO_01188 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IMBHKMNO_01189 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
IMBHKMNO_01190 4.83e-98 yneK - - S - - - Protein of unknown function (DUF2621)
IMBHKMNO_01191 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IMBHKMNO_01192 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IMBHKMNO_01193 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IMBHKMNO_01194 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
IMBHKMNO_01195 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IMBHKMNO_01196 4.4e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IMBHKMNO_01197 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMBHKMNO_01198 2.33e-43 ynzC - - S - - - UPF0291 protein
IMBHKMNO_01199 5.22e-145 yneB - - L - - - resolvase
IMBHKMNO_01200 2.89e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IMBHKMNO_01201 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMBHKMNO_01203 6.45e-95 yndM - - S - - - Protein of unknown function (DUF2512)
IMBHKMNO_01204 2.56e-184 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
IMBHKMNO_01205 4.12e-10 - - - - - - - -
IMBHKMNO_01206 2.47e-183 yndL - - S - - - Replication protein
IMBHKMNO_01207 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IMBHKMNO_01208 0.0 yobO - - M - - - Pectate lyase superfamily protein
IMBHKMNO_01210 4.49e-125 yvgO - - - - - - -
IMBHKMNO_01212 1.3e-85 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IMBHKMNO_01213 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IMBHKMNO_01214 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
IMBHKMNO_01215 9.37e-255 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_01216 5.75e-153 - - - S - - - Domain of unknown function (DUF3885)
IMBHKMNO_01219 1.08e-54 - - - - - - - -
IMBHKMNO_01221 4.01e-57 - - - S - - - Acetyltransferase (GNAT) domain
IMBHKMNO_01222 9.2e-122 yokK - - S - - - SMI1 / KNR4 family
IMBHKMNO_01223 1.06e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IMBHKMNO_01224 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IMBHKMNO_01225 7.73e-183 yoaP - - K - - - YoaP-like
IMBHKMNO_01226 3.3e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IMBHKMNO_01227 6.73e-23 - - - - - - - -
IMBHKMNO_01228 7.65e-17 - - - S - - - Bacterial transferase hexapeptide (six repeats)
IMBHKMNO_01229 8.42e-237 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IMBHKMNO_01230 1.93e-86 dinB - - S - - - DinB family
IMBHKMNO_01231 1.42e-84 yobV - - K - - - WYL domain
IMBHKMNO_01232 1.1e-41 yobV - - K - - - WYL domain
IMBHKMNO_01233 1.28e-26 - - - - - - - -
IMBHKMNO_01237 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IMBHKMNO_01238 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IMBHKMNO_01239 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IMBHKMNO_01240 4.12e-274 xylR - - GK - - - ROK family
IMBHKMNO_01241 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IMBHKMNO_01242 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IMBHKMNO_01243 2.09e-266 mrjp - - G - - - Major royal jelly protein
IMBHKMNO_01245 4.42e-28 - - - - - - - -
IMBHKMNO_01246 1.3e-30 - - - - - - - -
IMBHKMNO_01249 7.12e-41 - - - S - - - nuclease activity
IMBHKMNO_01250 1.15e-40 - - - - - - - -
IMBHKMNO_01251 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IMBHKMNO_01252 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IMBHKMNO_01253 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IMBHKMNO_01254 7.72e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMBHKMNO_01255 1.3e-89 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IMBHKMNO_01256 2.55e-309 - - - L ko:K06400 - ko00000 Recombinase
IMBHKMNO_01258 5.65e-117 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IMBHKMNO_01264 1.24e-35 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMBHKMNO_01265 3.66e-190 - - - S - - - Thymidylate synthase
IMBHKMNO_01266 3.07e-65 - - - S - - - Protein of unknown function (DUF1643)
IMBHKMNO_01269 3.93e-93 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IMBHKMNO_01270 4.58e-42 - - - O - - - Glutaredoxin
IMBHKMNO_01272 4.64e-76 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_01274 8.61e-138 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_01276 2.99e-203 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_01277 3.25e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_01278 2.21e-150 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_01279 6.24e-73 - - - S - - - NrdI Flavodoxin like
IMBHKMNO_01291 3.06e-26 - - - - - - - -
IMBHKMNO_01298 7.3e-100 - 2.1.1.37 - L ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IMBHKMNO_01299 7.49e-20 - 2.1.1.37 - L ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IMBHKMNO_01300 2.14e-111 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IMBHKMNO_01301 4.33e-92 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
IMBHKMNO_01304 2.09e-30 - - - S - - - protein conserved in bacteria
IMBHKMNO_01305 0.0 - - - L - - - DNA polymerase elongation subunit (Family B)
IMBHKMNO_01306 6.33e-220 - - - S - - - PD-(D/E)XK nuclease superfamily
IMBHKMNO_01307 4.18e-187 - - - L - - - DNA primase activity
IMBHKMNO_01308 2.06e-303 - - - L - - - DnaB-like helicase C terminal domain
IMBHKMNO_01310 5.06e-209 - - - S - - - AAA domain
IMBHKMNO_01311 1.76e-225 - - - - - - - -
IMBHKMNO_01312 7.66e-88 - - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
IMBHKMNO_01317 9.82e-276 - - - M - - - Parallel beta-helix repeats
IMBHKMNO_01318 5.52e-118 - - - S - - - Pfam:DUF867
IMBHKMNO_01320 1.72e-32 - - - S - - - YopX protein
IMBHKMNO_01323 1.63e-161 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IMBHKMNO_01324 5.53e-176 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IMBHKMNO_01326 1.31e-52 - - - - - - - -
IMBHKMNO_01330 6.81e-96 - - - - - - - -
IMBHKMNO_01334 3.85e-109 - - - S - - - Protein of unknown function (DUF1273)
IMBHKMNO_01342 8.16e-09 - - - S - - - YopX protein
IMBHKMNO_01343 1.58e-55 - - - - - - - -
IMBHKMNO_01347 9.24e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_01348 6.5e-31 - - - - - - - -
IMBHKMNO_01349 2.83e-240 - - - - - - - -
IMBHKMNO_01356 8.97e-32 - - - - - - - -
IMBHKMNO_01363 1.66e-33 - - - - - - - -
IMBHKMNO_01364 9.32e-06 - - - - - - - -
IMBHKMNO_01370 2.45e-88 yoaW - - - - - - -
IMBHKMNO_01378 2.79e-250 - - - L - - - Domain of unknown function (DUF4942)
IMBHKMNO_01379 4.2e-05 - - - L - - - SNF2 family N-terminal domain
IMBHKMNO_01380 1.39e-197 - - - - - - - -
IMBHKMNO_01383 7.71e-73 - - - D - - - Tubulin/FtsZ family, GTPase domain
IMBHKMNO_01387 0.0 - - - - - - - -
IMBHKMNO_01388 6.78e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMBHKMNO_01391 2.52e-281 - - - - - - - -
IMBHKMNO_01392 1.2e-49 - - - - - - - -
IMBHKMNO_01394 6.94e-132 - - - - - - - -
IMBHKMNO_01398 9.65e-84 - - - - - - - -
IMBHKMNO_01401 3.61e-71 - - - - - - - -
IMBHKMNO_01402 5.15e-112 - - - - - - - -
IMBHKMNO_01403 1.69e-149 - - - - - - - -
IMBHKMNO_01404 6.54e-72 - - - - - - - -
IMBHKMNO_01406 3.02e-65 - - - - - - - -
IMBHKMNO_01407 4.55e-97 - - - - - - - -
IMBHKMNO_01409 2.07e-75 - - - - - - - -
IMBHKMNO_01410 6.66e-67 - - - - - - - -
IMBHKMNO_01411 9.96e-222 - - - A - - - Belongs to the 'phage' integrase family
IMBHKMNO_01413 2.15e-50 - - - - - - - -
IMBHKMNO_01415 2.36e-75 - - - - - - - -
IMBHKMNO_01416 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IMBHKMNO_01417 1.64e-57 - - - S - - - Bacteriophage holin family
IMBHKMNO_01428 3.92e-29 - - - S - - - Phage gp6-like head-tail connector protein
IMBHKMNO_01433 2.27e-56 - - - K - - - BRO family, N-terminal domain
IMBHKMNO_01437 9.84e-40 - - - L - - - Psort location Cytoplasmic, score 8.87
IMBHKMNO_01438 4.33e-55 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IMBHKMNO_01439 1.48e-104 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IMBHKMNO_01440 1.21e-103 yuaE - - S - - - DinB superfamily
IMBHKMNO_01441 3.23e-139 - - - S - - - MOSC domain
IMBHKMNO_01442 4.99e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IMBHKMNO_01443 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMBHKMNO_01444 9.66e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IMBHKMNO_01445 3.78e-120 yuaB - - - - - - -
IMBHKMNO_01446 3.04e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IMBHKMNO_01447 1.82e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IMBHKMNO_01448 1.03e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMBHKMNO_01449 4.53e-158 - - - G - - - Cupin
IMBHKMNO_01450 5.31e-69 yjcN - - - - - - -
IMBHKMNO_01452 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IMBHKMNO_01453 2.34e-249 yubA - - S - - - transporter activity
IMBHKMNO_01454 5.49e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IMBHKMNO_01455 5.71e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IMBHKMNO_01456 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IMBHKMNO_01457 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IMBHKMNO_01458 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IMBHKMNO_01459 6.29e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IMBHKMNO_01460 6.36e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IMBHKMNO_01461 9.36e-55 - - - - - - - -
IMBHKMNO_01462 1.21e-243 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IMBHKMNO_01463 1.76e-99 yugU - - S - - - Uncharacterised protein family UPF0047
IMBHKMNO_01464 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IMBHKMNO_01465 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IMBHKMNO_01466 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IMBHKMNO_01467 2.51e-22 - - - - - - - -
IMBHKMNO_01468 3.47e-35 mstX - - S - - - Membrane-integrating protein Mistic
IMBHKMNO_01469 3.98e-230 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IMBHKMNO_01470 2.86e-93 yugN - - S - - - YugN-like family
IMBHKMNO_01472 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IMBHKMNO_01473 1.09e-130 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
IMBHKMNO_01474 4.34e-152 ycaC - - Q - - - Isochorismatase family
IMBHKMNO_01475 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IMBHKMNO_01476 6.43e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IMBHKMNO_01477 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IMBHKMNO_01478 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IMBHKMNO_01479 9.69e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IMBHKMNO_01480 3.75e-109 alaR - - K - - - Transcriptional regulator
IMBHKMNO_01481 5.72e-200 yugF - - I - - - Hydrolase
IMBHKMNO_01482 1e-53 yugE - - S - - - Domain of unknown function (DUF1871)
IMBHKMNO_01483 1.11e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IMBHKMNO_01484 3e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_01485 6.88e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IMBHKMNO_01486 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IMBHKMNO_01487 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
IMBHKMNO_01488 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IMBHKMNO_01489 5.29e-95 yuxK - - S - - - protein conserved in bacteria
IMBHKMNO_01490 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
IMBHKMNO_01491 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IMBHKMNO_01492 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IMBHKMNO_01493 2.03e-249 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IMBHKMNO_01494 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_01495 1.11e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMBHKMNO_01496 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMBHKMNO_01498 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IMBHKMNO_01499 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IMBHKMNO_01500 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IMBHKMNO_01501 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IMBHKMNO_01502 2.38e-99 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IMBHKMNO_01503 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IMBHKMNO_01504 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IMBHKMNO_01505 4.86e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IMBHKMNO_01506 1.9e-146 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_01507 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_01509 2.7e-76 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
IMBHKMNO_01510 2.66e-11 - - - S - - - DegQ (SacQ) family
IMBHKMNO_01511 6.25e-69 yuzC - - - - - - -
IMBHKMNO_01512 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IMBHKMNO_01513 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMBHKMNO_01514 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IMBHKMNO_01515 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
IMBHKMNO_01516 5.46e-51 yueH - - S - - - YueH-like protein
IMBHKMNO_01517 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IMBHKMNO_01518 2.67e-238 yueF - - S - - - transporter activity
IMBHKMNO_01519 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
IMBHKMNO_01520 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IMBHKMNO_01521 4.12e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_01522 1.55e-99 yueC - - S - - - Family of unknown function (DUF5383)
IMBHKMNO_01523 0.0 yueB - - S - - - type VII secretion protein EsaA
IMBHKMNO_01524 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IMBHKMNO_01525 9.26e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IMBHKMNO_01526 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IMBHKMNO_01527 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
IMBHKMNO_01528 1.49e-291 yukF - - QT - - - Transcriptional regulator
IMBHKMNO_01529 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IMBHKMNO_01530 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IMBHKMNO_01531 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IMBHKMNO_01532 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_01533 1.43e-222 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IMBHKMNO_01534 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IMBHKMNO_01535 3.9e-286 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IMBHKMNO_01536 1.28e-173 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01537 1.53e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
IMBHKMNO_01538 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IMBHKMNO_01539 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IMBHKMNO_01540 3.88e-274 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IMBHKMNO_01541 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMBHKMNO_01542 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IMBHKMNO_01543 7.23e-155 yuiC - - S - - - protein conserved in bacteria
IMBHKMNO_01544 8.54e-46 yuiB - - S - - - Putative membrane protein
IMBHKMNO_01545 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IMBHKMNO_01546 3.44e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IMBHKMNO_01548 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IMBHKMNO_01549 5.68e-40 - - - - - - - -
IMBHKMNO_01550 3.42e-92 - - - CP - - - Membrane
IMBHKMNO_01551 1.13e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IMBHKMNO_01553 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
IMBHKMNO_01555 4.34e-25 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IMBHKMNO_01556 2.12e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01557 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IMBHKMNO_01558 1.85e-206 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMBHKMNO_01559 4.26e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMBHKMNO_01560 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IMBHKMNO_01561 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IMBHKMNO_01562 1.34e-72 yuzD - - S - - - protein conserved in bacteria
IMBHKMNO_01563 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IMBHKMNO_01564 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IMBHKMNO_01565 9.2e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IMBHKMNO_01566 5.41e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMBHKMNO_01567 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IMBHKMNO_01568 3.64e-249 yutH - - S - - - Spore coat protein
IMBHKMNO_01569 7.5e-111 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IMBHKMNO_01570 6.12e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IMBHKMNO_01571 3.79e-96 yutE - - S - - - Protein of unknown function DUF86
IMBHKMNO_01572 2.15e-61 yutD - - S - - - protein conserved in bacteria
IMBHKMNO_01573 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMBHKMNO_01574 4.77e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IMBHKMNO_01575 4.76e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IMBHKMNO_01576 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMBHKMNO_01577 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IMBHKMNO_01578 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
IMBHKMNO_01579 1.29e-81 - - - S - - - phosphoglycolate phosphatase activity
IMBHKMNO_01580 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IMBHKMNO_01581 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IMBHKMNO_01583 3.52e-227 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
IMBHKMNO_01584 7.33e-84 - - - - - - - -
IMBHKMNO_01585 7.4e-275 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_01586 1.03e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IMBHKMNO_01587 1.63e-297 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IMBHKMNO_01588 7.06e-218 bsn - - L - - - Ribonuclease
IMBHKMNO_01589 1.07e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_01590 1.39e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IMBHKMNO_01591 1.52e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IMBHKMNO_01592 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IMBHKMNO_01593 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMBHKMNO_01594 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IMBHKMNO_01595 2.33e-238 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IMBHKMNO_01596 1.35e-211 - - - K - - - helix_turn_helix, mercury resistance
IMBHKMNO_01598 5.4e-95 - - - - - - - -
IMBHKMNO_01599 4.94e-28 - - - S - - - Sporulation delaying protein SdpA
IMBHKMNO_01601 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IMBHKMNO_01602 3.7e-259 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IMBHKMNO_01603 1.36e-159 - - - Q - - - ubiE/COQ5 methyltransferase family
IMBHKMNO_01604 6.17e-102 yncE - - S - - - Protein of unknown function (DUF2691)
IMBHKMNO_01605 3.07e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IMBHKMNO_01606 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IMBHKMNO_01607 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IMBHKMNO_01608 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMBHKMNO_01609 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IMBHKMNO_01610 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IMBHKMNO_01611 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMBHKMNO_01612 3.66e-186 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IMBHKMNO_01613 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IMBHKMNO_01614 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMBHKMNO_01615 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
IMBHKMNO_01616 1.64e-72 yusE - - CO - - - Thioredoxin
IMBHKMNO_01617 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IMBHKMNO_01618 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
IMBHKMNO_01619 3.42e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IMBHKMNO_01620 2.05e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IMBHKMNO_01621 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IMBHKMNO_01622 2.59e-276 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IMBHKMNO_01623 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IMBHKMNO_01624 5.35e-215 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IMBHKMNO_01625 3.2e-58 - - - - - - - -
IMBHKMNO_01626 2.58e-71 yusN - - M - - - Coat F domain
IMBHKMNO_01627 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IMBHKMNO_01628 0.0 yusP - - P - - - Major facilitator superfamily
IMBHKMNO_01629 1.39e-202 - - - K - - - Transcriptional regulator
IMBHKMNO_01630 9.75e-175 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
IMBHKMNO_01631 4.9e-240 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMBHKMNO_01632 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
IMBHKMNO_01633 9.06e-193 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IMBHKMNO_01634 7.24e-58 - - - S - - - YusW-like protein
IMBHKMNO_01635 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IMBHKMNO_01636 3.04e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01637 4.12e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IMBHKMNO_01638 6.82e-308 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMBHKMNO_01639 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_01640 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_01641 4.63e-33 - - - - - - - -
IMBHKMNO_01642 1.8e-200 yuxN - - K - - - Transcriptional regulator
IMBHKMNO_01643 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IMBHKMNO_01644 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
IMBHKMNO_01645 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IMBHKMNO_01646 5.31e-245 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IMBHKMNO_01647 9.16e-264 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IMBHKMNO_01648 1.19e-138 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_01649 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_01650 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IMBHKMNO_01651 1.67e-191 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IMBHKMNO_01652 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IMBHKMNO_01653 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IMBHKMNO_01654 1.37e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_01655 3.23e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IMBHKMNO_01656 9.93e-285 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IMBHKMNO_01657 1.87e-229 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_01658 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IMBHKMNO_01659 3.51e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01660 4.61e-220 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IMBHKMNO_01661 0.0 yvrG - - T - - - Histidine kinase
IMBHKMNO_01662 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_01663 1.67e-50 - - - - - - - -
IMBHKMNO_01664 8.18e-132 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IMBHKMNO_01665 1.88e-21 - - - S - - - YvrJ protein family
IMBHKMNO_01666 3.11e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IMBHKMNO_01667 4.84e-88 yvrL - - S - - - Regulatory protein YrvL
IMBHKMNO_01668 9.78e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IMBHKMNO_01669 5.57e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_01670 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_01671 7.41e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMBHKMNO_01672 1.02e-158 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IMBHKMNO_01673 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IMBHKMNO_01674 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IMBHKMNO_01675 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IMBHKMNO_01676 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IMBHKMNO_01677 1.65e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IMBHKMNO_01678 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IMBHKMNO_01679 1.57e-122 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IMBHKMNO_01680 1.69e-145 yfiK - - K - - - Regulator
IMBHKMNO_01681 1.01e-251 - - - T - - - Histidine kinase
IMBHKMNO_01682 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IMBHKMNO_01683 9.59e-247 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IMBHKMNO_01684 7.71e-257 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IMBHKMNO_01685 1.77e-200 yvgN - - S - - - reductase
IMBHKMNO_01686 1.38e-113 yvgO - - - - - - -
IMBHKMNO_01687 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IMBHKMNO_01688 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IMBHKMNO_01689 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMBHKMNO_01690 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IMBHKMNO_01691 6.36e-130 yvgT - - S - - - membrane
IMBHKMNO_01692 3.29e-191 - - - S - - - Metallo-peptidase family M12
IMBHKMNO_01693 2.06e-93 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IMBHKMNO_01694 3.33e-140 bdbD - - O - - - Thioredoxin
IMBHKMNO_01695 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IMBHKMNO_01696 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IMBHKMNO_01697 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
IMBHKMNO_01698 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IMBHKMNO_01699 2.88e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IMBHKMNO_01700 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMBHKMNO_01701 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_01702 4.12e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IMBHKMNO_01703 4.31e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_01704 4.28e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IMBHKMNO_01705 5.8e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMBHKMNO_01706 5.73e-154 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMBHKMNO_01707 2.05e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IMBHKMNO_01708 4.15e-168 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IMBHKMNO_01709 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IMBHKMNO_01710 6.6e-205 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IMBHKMNO_01711 1.6e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMBHKMNO_01712 3.28e-63 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IMBHKMNO_01713 5.05e-58 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IMBHKMNO_01715 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMBHKMNO_01716 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IMBHKMNO_01717 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IMBHKMNO_01718 2.65e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IMBHKMNO_01719 1.64e-47 yvzC - - K - - - transcriptional
IMBHKMNO_01720 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IMBHKMNO_01721 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IMBHKMNO_01722 2.44e-69 yvaP - - K - - - transcriptional
IMBHKMNO_01723 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
IMBHKMNO_01724 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IMBHKMNO_01725 8.92e-171 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMBHKMNO_01726 3.17e-153 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMBHKMNO_01727 1.27e-160 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_01728 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IMBHKMNO_01729 2.67e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IMBHKMNO_01730 9.74e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IMBHKMNO_01731 4.07e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IMBHKMNO_01732 9.8e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IMBHKMNO_01733 8.83e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IMBHKMNO_01734 5.39e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IMBHKMNO_01735 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IMBHKMNO_01736 4.24e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IMBHKMNO_01737 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IMBHKMNO_01738 2.2e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IMBHKMNO_01739 1.54e-156 yvbI - - M - - - Membrane
IMBHKMNO_01740 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IMBHKMNO_01741 1.38e-91 yvbK - - K - - - acetyltransferase
IMBHKMNO_01742 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IMBHKMNO_01743 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IMBHKMNO_01744 4.28e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IMBHKMNO_01745 3.13e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IMBHKMNO_01746 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IMBHKMNO_01747 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IMBHKMNO_01749 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IMBHKMNO_01750 1.29e-259 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IMBHKMNO_01751 3.08e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_01752 8.74e-160 yvbU - - K - - - Transcriptional regulator
IMBHKMNO_01753 1.23e-201 yvbV - - EG - - - EamA-like transporter family
IMBHKMNO_01754 2.33e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_01756 5.21e-193 gntR - - K - - - RpiR family transcriptional regulator
IMBHKMNO_01757 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IMBHKMNO_01758 3.22e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IMBHKMNO_01759 4.55e-10 - - - S ko:K07483 - ko00000 leucine-zipper of insertion element IS481
IMBHKMNO_01760 1.68e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IMBHKMNO_01761 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IMBHKMNO_01762 3.55e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IMBHKMNO_01763 8.77e-282 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMBHKMNO_01764 2.55e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IMBHKMNO_01765 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IMBHKMNO_01766 9.31e-309 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IMBHKMNO_01767 4.01e-44 yvfG - - S - - - YvfG protein
IMBHKMNO_01768 8.75e-235 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IMBHKMNO_01769 2.72e-282 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IMBHKMNO_01770 8.13e-79 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IMBHKMNO_01771 1.92e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IMBHKMNO_01772 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_01773 5.18e-250 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IMBHKMNO_01774 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IMBHKMNO_01775 3.62e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IMBHKMNO_01776 9.87e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IMBHKMNO_01777 2.03e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IMBHKMNO_01778 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IMBHKMNO_01779 4.3e-278 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IMBHKMNO_01780 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IMBHKMNO_01781 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IMBHKMNO_01782 1.94e-154 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IMBHKMNO_01783 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IMBHKMNO_01784 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IMBHKMNO_01786 4.68e-126 ywjB - - H - - - RibD C-terminal domain
IMBHKMNO_01787 1.06e-145 yyaS - - S ko:K07149 - ko00000 Membrane
IMBHKMNO_01788 3.29e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMBHKMNO_01789 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IMBHKMNO_01790 4.37e-71 - - - S - - - Protein of unknown function (DUF3237)
IMBHKMNO_01791 2.2e-18 - - - S - - - Protein of unknown function (DUF1433)
IMBHKMNO_01792 3.09e-53 - - - S - - - Protein of unknown function (DUF1433)
IMBHKMNO_01793 4.44e-297 - - - I - - - Pfam Lipase (class 3)
IMBHKMNO_01794 1.94e-47 - - - - - - - -
IMBHKMNO_01796 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IMBHKMNO_01797 3.19e-282 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
IMBHKMNO_01798 1.57e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IMBHKMNO_01799 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IMBHKMNO_01800 5.71e-125 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IMBHKMNO_01801 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IMBHKMNO_01802 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IMBHKMNO_01803 3.4e-138 malA - - S - - - Protein of unknown function (DUF1189)
IMBHKMNO_01804 1.85e-178 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IMBHKMNO_01805 7.72e-280 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IMBHKMNO_01806 1.9e-264 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IMBHKMNO_01807 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IMBHKMNO_01808 6.6e-207 yvdE - - K - - - Transcriptional regulator
IMBHKMNO_01809 8.57e-134 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IMBHKMNO_01810 5.31e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IMBHKMNO_01811 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IMBHKMNO_01812 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IMBHKMNO_01813 2.06e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMBHKMNO_01814 2.26e-104 - - - M - - - Ribonuclease
IMBHKMNO_01815 2.82e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IMBHKMNO_01816 2.66e-48 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IMBHKMNO_01817 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IMBHKMNO_01818 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IMBHKMNO_01819 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IMBHKMNO_01820 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IMBHKMNO_01821 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IMBHKMNO_01822 1.15e-173 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IMBHKMNO_01824 2.49e-312 yvcD - - S - - - COG0457 FOG TPR repeat
IMBHKMNO_01825 5.55e-245 sasA - - T - - - Histidine kinase
IMBHKMNO_01826 1.62e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_01827 5.51e-73 - - - - - - - -
IMBHKMNO_01828 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IMBHKMNO_01829 1.91e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IMBHKMNO_01830 8e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IMBHKMNO_01831 3.79e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMBHKMNO_01832 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMBHKMNO_01833 3.22e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IMBHKMNO_01834 1.11e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMBHKMNO_01835 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IMBHKMNO_01836 1.73e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMBHKMNO_01837 2.93e-177 yvpB - - NU - - - protein conserved in bacteria
IMBHKMNO_01838 4.35e-115 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IMBHKMNO_01839 2.72e-156 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IMBHKMNO_01840 1.02e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMBHKMNO_01841 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMBHKMNO_01842 7.85e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMBHKMNO_01843 6.36e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IMBHKMNO_01844 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IMBHKMNO_01845 8.92e-136 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IMBHKMNO_01846 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IMBHKMNO_01847 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IMBHKMNO_01848 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IMBHKMNO_01849 9.16e-218 yvlB - - S - - - Putative adhesin
IMBHKMNO_01850 4.87e-66 yvlA - - - - - - -
IMBHKMNO_01851 1.78e-51 yvkN - - - - - - -
IMBHKMNO_01852 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IMBHKMNO_01853 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IMBHKMNO_01854 2.59e-45 csbA - - S - - - protein conserved in bacteria
IMBHKMNO_01855 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IMBHKMNO_01856 1.35e-143 yvkB - - K - - - Transcriptional regulator
IMBHKMNO_01857 2.93e-298 yvkA - - P - - - -transporter
IMBHKMNO_01858 4.08e-34 - - - Q - - - Thioesterase domain
IMBHKMNO_01860 5.04e-232 - - - S - - - Psort location CytoplasmicMembrane, score
IMBHKMNO_01861 4.66e-59 - - - E - - - Saccharopine dehydrogenase
IMBHKMNO_01862 2.38e-118 - - - V - - - ABC transporter transmembrane region
IMBHKMNO_01863 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
IMBHKMNO_01864 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
IMBHKMNO_01865 5.02e-82 - - - IQ - - - KR domain
IMBHKMNO_01867 2.02e-19 - - - L ko:K07497 - ko00000 transposition
IMBHKMNO_01869 4.86e-279 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMBHKMNO_01870 2.47e-73 swrA - - S - - - Swarming motility protein
IMBHKMNO_01871 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IMBHKMNO_01872 1.72e-304 ywoF - - P - - - Right handed beta helix region
IMBHKMNO_01873 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IMBHKMNO_01874 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IMBHKMNO_01875 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IMBHKMNO_01876 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_01877 5.45e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMBHKMNO_01878 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMBHKMNO_01879 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMBHKMNO_01880 1.35e-89 - - - - - - - -
IMBHKMNO_01881 7.78e-11 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IMBHKMNO_01882 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IMBHKMNO_01883 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IMBHKMNO_01884 1.3e-152 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMBHKMNO_01885 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IMBHKMNO_01886 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IMBHKMNO_01887 9.36e-107 yviE - - - - - - -
IMBHKMNO_01888 1.2e-208 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IMBHKMNO_01889 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IMBHKMNO_01890 2.2e-105 yvyG - - NOU - - - FlgN protein
IMBHKMNO_01891 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IMBHKMNO_01892 1.1e-97 yvyF - - S - - - flagellar protein
IMBHKMNO_01893 5.83e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IMBHKMNO_01894 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IMBHKMNO_01895 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMBHKMNO_01896 8.81e-204 degV - - S - - - protein conserved in bacteria
IMBHKMNO_01897 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_01898 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IMBHKMNO_01899 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IMBHKMNO_01900 1.3e-233 yvhJ - - K - - - Transcriptional regulator
IMBHKMNO_01901 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IMBHKMNO_01902 1.63e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IMBHKMNO_01903 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IMBHKMNO_01904 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IMBHKMNO_01905 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IMBHKMNO_01906 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMBHKMNO_01907 7.22e-282 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IMBHKMNO_01908 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_01909 2.44e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IMBHKMNO_01910 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IMBHKMNO_01911 0.0 lytB - - D - - - Stage II sporulation protein
IMBHKMNO_01912 1.86e-64 - - - - - - - -
IMBHKMNO_01913 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IMBHKMNO_01914 7.02e-268 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMBHKMNO_01915 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IMBHKMNO_01916 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IMBHKMNO_01917 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IMBHKMNO_01918 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMBHKMNO_01919 0.0 - - - M - - - Glycosyltransferase like family 2
IMBHKMNO_01920 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IMBHKMNO_01921 1.23e-181 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IMBHKMNO_01922 1.5e-278 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMBHKMNO_01923 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IMBHKMNO_01924 1.4e-233 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IMBHKMNO_01925 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IMBHKMNO_01926 2.36e-249 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IMBHKMNO_01927 1.17e-269 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IMBHKMNO_01928 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
IMBHKMNO_01929 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IMBHKMNO_01930 1.89e-228 ywtF_2 - - K - - - Transcriptional regulator
IMBHKMNO_01931 4.34e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IMBHKMNO_01932 9.02e-72 yttA - - S - - - Pfam Transposase IS66
IMBHKMNO_01933 7.5e-302 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IMBHKMNO_01934 4.04e-29 ywtC - - - - - - -
IMBHKMNO_01935 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IMBHKMNO_01936 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IMBHKMNO_01937 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IMBHKMNO_01938 4.41e-242 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IMBHKMNO_01939 1.08e-247 - - - E - - - Spore germination protein
IMBHKMNO_01940 4.16e-259 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
IMBHKMNO_01941 8.63e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IMBHKMNO_01942 1.39e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMBHKMNO_01943 7.96e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IMBHKMNO_01944 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IMBHKMNO_01945 1.54e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMBHKMNO_01946 5.69e-207 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IMBHKMNO_01947 3.54e-117 batE - - T - - - Sh3 type 3 domain protein
IMBHKMNO_01948 2.49e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IMBHKMNO_01949 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IMBHKMNO_01950 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IMBHKMNO_01951 7.59e-215 alsR - - K - - - LysR substrate binding domain
IMBHKMNO_01952 2.02e-304 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMBHKMNO_01953 3.43e-163 ywrJ - - - - - - -
IMBHKMNO_01954 1.29e-185 cotB - - - ko:K06325 - ko00000 -
IMBHKMNO_01955 2.27e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
IMBHKMNO_01956 1.64e-18 - - - - - - - -
IMBHKMNO_01957 9.88e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMBHKMNO_01959 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IMBHKMNO_01960 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IMBHKMNO_01961 9.9e-131 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IMBHKMNO_01962 1.23e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IMBHKMNO_01964 2.12e-120 ywqN - - S - - - NAD(P)H-dependent
IMBHKMNO_01965 1.39e-201 - - - K - - - Transcriptional regulator
IMBHKMNO_01966 3.14e-166 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IMBHKMNO_01967 1.53e-122 - - - - - - - -
IMBHKMNO_01969 1.66e-65 - - - - - - - -
IMBHKMNO_01970 2.72e-115 - - - - - - - -
IMBHKMNO_01971 7.56e-44 - - - M - - - COG3209 Rhs family protein
IMBHKMNO_01972 2.26e-74 - - - T - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
IMBHKMNO_01973 2.05e-66 - - - - - - - -
IMBHKMNO_01974 0.0 ywqJ - - S - - - Pre-toxin TG
IMBHKMNO_01975 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
IMBHKMNO_01978 1.4e-190 ywqG - - S - - - Domain of unknown function (DUF1963)
IMBHKMNO_01979 7.16e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMBHKMNO_01980 1.06e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IMBHKMNO_01981 6.33e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IMBHKMNO_01982 1.43e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IMBHKMNO_01983 1.74e-21 - - - - - - - -
IMBHKMNO_01984 0.0 ywqB - - S - - - SWIM zinc finger
IMBHKMNO_01985 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IMBHKMNO_01986 3.72e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IMBHKMNO_01987 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IMBHKMNO_01988 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IMBHKMNO_01989 4.49e-82 ywpG - - - - - - -
IMBHKMNO_01990 1.07e-89 ywpF - - S - - - YwpF-like protein
IMBHKMNO_01991 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IMBHKMNO_01992 9.04e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IMBHKMNO_01993 9.42e-258 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IMBHKMNO_01994 1.05e-184 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IMBHKMNO_01995 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IMBHKMNO_01996 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IMBHKMNO_01997 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IMBHKMNO_01998 3.58e-93 ywoH - - K - - - transcriptional
IMBHKMNO_01999 4.1e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_02000 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IMBHKMNO_02001 3.27e-311 ywoD - - EGP - - - Major facilitator superfamily
IMBHKMNO_02002 1.37e-133 yjgF - - Q - - - Isochorismatase family
IMBHKMNO_02003 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IMBHKMNO_02004 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IMBHKMNO_02005 8.52e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IMBHKMNO_02006 1.66e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IMBHKMNO_02007 5.45e-94 ywnJ - - S - - - VanZ like family
IMBHKMNO_02008 2.65e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IMBHKMNO_02009 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IMBHKMNO_02011 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
IMBHKMNO_02012 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMBHKMNO_02013 8.03e-79 ywnC - - S - - - Family of unknown function (DUF5362)
IMBHKMNO_02014 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IMBHKMNO_02015 8.87e-88 ywnA - - K - - - Transcriptional regulator
IMBHKMNO_02016 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IMBHKMNO_02017 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IMBHKMNO_02018 2.35e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IMBHKMNO_02019 2.01e-16 csbD - - K - - - CsbD-like
IMBHKMNO_02020 1.49e-107 ywmF - - S - - - Peptidase M50
IMBHKMNO_02021 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IMBHKMNO_02022 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMBHKMNO_02023 1.06e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMBHKMNO_02025 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IMBHKMNO_02026 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IMBHKMNO_02027 8.17e-242 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IMBHKMNO_02028 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMBHKMNO_02029 1.89e-171 ywmB - - S - - - TATA-box binding
IMBHKMNO_02030 2.25e-45 ywzB - - S - - - membrane
IMBHKMNO_02031 1.02e-117 ywmA - - - - - - -
IMBHKMNO_02032 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IMBHKMNO_02033 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMBHKMNO_02034 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMBHKMNO_02035 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMBHKMNO_02036 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMBHKMNO_02037 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMBHKMNO_02038 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMBHKMNO_02039 1.05e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IMBHKMNO_02040 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IMBHKMNO_02041 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMBHKMNO_02042 8.08e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMBHKMNO_02043 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
IMBHKMNO_02044 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IMBHKMNO_02045 1.99e-99 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMBHKMNO_02046 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
IMBHKMNO_02047 4.38e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IMBHKMNO_02048 1.21e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IMBHKMNO_02049 2.99e-149 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IMBHKMNO_02050 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IMBHKMNO_02052 1.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IMBHKMNO_02053 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMBHKMNO_02054 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_02055 2.45e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IMBHKMNO_02056 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IMBHKMNO_02057 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IMBHKMNO_02058 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IMBHKMNO_02059 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IMBHKMNO_02060 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMBHKMNO_02061 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IMBHKMNO_02062 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMBHKMNO_02063 6.37e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMBHKMNO_02064 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IMBHKMNO_02065 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IMBHKMNO_02066 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
IMBHKMNO_02067 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IMBHKMNO_02068 2.79e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IMBHKMNO_02069 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IMBHKMNO_02070 5.74e-284 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IMBHKMNO_02071 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IMBHKMNO_02072 1.13e-58 ywjC - - - - - - -
IMBHKMNO_02073 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IMBHKMNO_02074 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMBHKMNO_02075 1.18e-133 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMBHKMNO_02076 8.39e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IMBHKMNO_02077 6.28e-124 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IMBHKMNO_02078 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IMBHKMNO_02079 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMBHKMNO_02080 2.05e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IMBHKMNO_02081 5.91e-176 ywiC - - S - - - YwiC-like protein
IMBHKMNO_02082 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IMBHKMNO_02083 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IMBHKMNO_02084 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IMBHKMNO_02085 1.14e-96 ywiB - - S - - - protein conserved in bacteria
IMBHKMNO_02087 1.1e-311 ywhL - - CO - - - amine dehydrogenase activity
IMBHKMNO_02088 3.29e-298 ywhK - - CO - - - amine dehydrogenase activity
IMBHKMNO_02089 4.08e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_02091 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
IMBHKMNO_02092 2.41e-45 - - - - - - - -
IMBHKMNO_02093 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
IMBHKMNO_02095 3.44e-100 - - - CP - - - Membrane
IMBHKMNO_02098 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IMBHKMNO_02099 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IMBHKMNO_02100 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMBHKMNO_02101 1.68e-103 - - - - - - - -
IMBHKMNO_02102 3.32e-124 ywhD - - S - - - YwhD family
IMBHKMNO_02103 3.84e-153 ywhC - - S - - - Peptidase family M50
IMBHKMNO_02104 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IMBHKMNO_02105 4.16e-93 ywhA - - K - - - Transcriptional regulator
IMBHKMNO_02106 3.08e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
IMBHKMNO_02107 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
IMBHKMNO_02108 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IMBHKMNO_02109 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IMBHKMNO_02110 3.52e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IMBHKMNO_02111 1.8e-66 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
IMBHKMNO_02112 3.1e-119 - - - S - - - membrane
IMBHKMNO_02113 2.73e-210 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02114 2.96e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
IMBHKMNO_02117 3.18e-236 - - - - - - - -
IMBHKMNO_02119 2.06e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IMBHKMNO_02120 9.17e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_02121 3.57e-215 - - - S - - - Conserved hypothetical protein 698
IMBHKMNO_02122 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IMBHKMNO_02123 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IMBHKMNO_02124 1.98e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IMBHKMNO_02125 1.56e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IMBHKMNO_02126 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IMBHKMNO_02127 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IMBHKMNO_02128 4.65e-180 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_02129 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IMBHKMNO_02130 1.15e-145 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IMBHKMNO_02131 9.55e-285 ywfA - - EGP - - - -transporter
IMBHKMNO_02132 8.1e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IMBHKMNO_02133 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IMBHKMNO_02134 0.0 rocB - - E - - - arginine degradation protein
IMBHKMNO_02135 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IMBHKMNO_02136 6.34e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IMBHKMNO_02137 4.11e-203 - - - T - - - Histidine kinase
IMBHKMNO_02138 4.29e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_02139 1.31e-100 - - - - - - - -
IMBHKMNO_02140 1.48e-153 - - - S - - - ABC-2 family transporter protein
IMBHKMNO_02141 2.66e-221 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02142 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IMBHKMNO_02143 1.16e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IMBHKMNO_02144 4.32e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IMBHKMNO_02145 3.99e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMBHKMNO_02146 1.19e-234 spsG - - M - - - Spore Coat
IMBHKMNO_02147 9.7e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
IMBHKMNO_02148 1.23e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IMBHKMNO_02149 3.72e-203 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IMBHKMNO_02150 5.07e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IMBHKMNO_02151 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IMBHKMNO_02152 9.06e-184 spsA - - M - - - Spore Coat
IMBHKMNO_02153 1.39e-77 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IMBHKMNO_02154 2.17e-76 ywdK - - S - - - small membrane protein
IMBHKMNO_02155 1.13e-292 ywdJ - - F - - - Xanthine uracil
IMBHKMNO_02156 3.37e-59 ywdI - - S - - - Family of unknown function (DUF5327)
IMBHKMNO_02157 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMBHKMNO_02158 2.42e-194 ywdF - - S - - - Glycosyltransferase like family 2
IMBHKMNO_02160 4.04e-115 ywdD - - - - - - -
IMBHKMNO_02161 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IMBHKMNO_02162 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IMBHKMNO_02163 3.52e-26 ywdA - - - - - - -
IMBHKMNO_02164 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IMBHKMNO_02165 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_02167 1.57e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IMBHKMNO_02169 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IMBHKMNO_02170 1.15e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_02171 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IMBHKMNO_02172 1.58e-263 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IMBHKMNO_02173 1.91e-103 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IMBHKMNO_02174 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IMBHKMNO_02175 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IMBHKMNO_02176 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IMBHKMNO_02177 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMBHKMNO_02178 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IMBHKMNO_02179 6.72e-47 ydaS - - S - - - membrane
IMBHKMNO_02180 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IMBHKMNO_02181 6e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMBHKMNO_02182 2.84e-80 gtcA - - S - - - GtrA-like protein
IMBHKMNO_02183 3.72e-145 - - - K - - - Bacterial regulatory proteins, tetR family
IMBHKMNO_02185 5.07e-166 - - - H - - - Methionine biosynthesis protein MetW
IMBHKMNO_02186 1.15e-170 - - - S - - - Streptomycin biosynthesis protein StrF
IMBHKMNO_02187 5.13e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IMBHKMNO_02188 1.72e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IMBHKMNO_02189 4.76e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IMBHKMNO_02190 3.06e-174 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IMBHKMNO_02191 4.83e-202 ywbI - - K - - - Transcriptional regulator
IMBHKMNO_02192 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IMBHKMNO_02193 1.86e-143 ywbG - - M - - - effector of murein hydrolase
IMBHKMNO_02194 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IMBHKMNO_02195 1.98e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IMBHKMNO_02196 5.81e-218 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IMBHKMNO_02197 2.08e-284 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IMBHKMNO_02198 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IMBHKMNO_02199 4.68e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMBHKMNO_02200 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IMBHKMNO_02201 6.3e-209 gspA - - M - - - General stress
IMBHKMNO_02202 2.5e-64 ywaE - - K - - - Transcriptional regulator
IMBHKMNO_02203 1.42e-248 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMBHKMNO_02204 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IMBHKMNO_02205 1.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IMBHKMNO_02206 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
IMBHKMNO_02207 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_02208 4.25e-292 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IMBHKMNO_02209 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_02210 1.08e-289 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IMBHKMNO_02211 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IMBHKMNO_02212 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IMBHKMNO_02213 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_02214 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMBHKMNO_02215 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IMBHKMNO_02216 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IMBHKMNO_02218 6.01e-141 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IMBHKMNO_02219 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02220 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02221 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IMBHKMNO_02222 4.51e-77 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IMBHKMNO_02223 1.27e-290 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMBHKMNO_02224 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_02225 1.53e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_02226 4.93e-303 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMBHKMNO_02227 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMBHKMNO_02228 2.85e-210 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IMBHKMNO_02229 1.3e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IMBHKMNO_02230 1.07e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IMBHKMNO_02231 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IMBHKMNO_02232 3.08e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IMBHKMNO_02233 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IMBHKMNO_02234 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMBHKMNO_02235 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IMBHKMNO_02236 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IMBHKMNO_02237 1.36e-242 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IMBHKMNO_02238 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IMBHKMNO_02239 9.57e-289 cimH - - C - - - COG3493 Na citrate symporter
IMBHKMNO_02240 4.01e-199 yxkH - - G - - - Polysaccharide deacetylase
IMBHKMNO_02241 2.62e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_02242 5.76e-212 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IMBHKMNO_02243 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMBHKMNO_02244 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
IMBHKMNO_02245 9.29e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IMBHKMNO_02246 2.22e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IMBHKMNO_02249 6.11e-111 yxjI - - S - - - LURP-one-related
IMBHKMNO_02250 1.33e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IMBHKMNO_02251 2.31e-200 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IMBHKMNO_02252 2.85e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMBHKMNO_02253 1.25e-124 - - - T - - - Domain of unknown function (DUF4163)
IMBHKMNO_02254 2.68e-67 yxiS - - - - - - -
IMBHKMNO_02255 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IMBHKMNO_02256 1.35e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IMBHKMNO_02257 8.12e-185 bglS - - M - - - licheninase activity
IMBHKMNO_02258 3.41e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IMBHKMNO_02259 2.47e-280 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IMBHKMNO_02260 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IMBHKMNO_02261 1.34e-257 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IMBHKMNO_02262 7.23e-209 yxxF - - EG - - - EamA-like transporter family
IMBHKMNO_02263 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
IMBHKMNO_02264 0.0 - - - L - - - HKD family nuclease
IMBHKMNO_02265 9.75e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IMBHKMNO_02266 7.46e-203 - - - L - - - AAA domain
IMBHKMNO_02267 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IMBHKMNO_02268 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IMBHKMNO_02269 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IMBHKMNO_02270 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IMBHKMNO_02271 4.51e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IMBHKMNO_02272 3.38e-225 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IMBHKMNO_02273 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IMBHKMNO_02274 3.85e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IMBHKMNO_02275 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMBHKMNO_02276 8.25e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMBHKMNO_02277 8.24e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IMBHKMNO_02278 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
IMBHKMNO_02281 3.03e-37 yxeE - - - - - - -
IMBHKMNO_02282 5.09e-35 yxeD - - - - - - -
IMBHKMNO_02283 2.8e-46 - - - - - - - -
IMBHKMNO_02284 8.69e-230 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IMBHKMNO_02285 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
IMBHKMNO_02286 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IMBHKMNO_02287 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02288 1.67e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_02289 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_02290 4.69e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IMBHKMNO_02291 1.03e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IMBHKMNO_02292 8.87e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IMBHKMNO_02293 5.18e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IMBHKMNO_02294 5e-292 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IMBHKMNO_02295 2.29e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IMBHKMNO_02296 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IMBHKMNO_02297 2.4e-232 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IMBHKMNO_02298 2.08e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IMBHKMNO_02299 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IMBHKMNO_02300 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IMBHKMNO_02301 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IMBHKMNO_02302 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IMBHKMNO_02303 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IMBHKMNO_02305 5.06e-194 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IMBHKMNO_02306 6.16e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_02307 4.6e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_02308 1.38e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IMBHKMNO_02309 2.68e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IMBHKMNO_02310 7.26e-31 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMBHKMNO_02311 3.21e-23 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
IMBHKMNO_02316 9.9e-284 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMBHKMNO_02317 7.81e-176 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
IMBHKMNO_02318 3.55e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMBHKMNO_02319 6.09e-190 yxaL - - S - - - PQQ-like domain
IMBHKMNO_02320 1.97e-82 - - - S - - - Family of unknown function (DUF5391)
IMBHKMNO_02321 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IMBHKMNO_02322 1.14e-257 - - - EGP - - - Major Facilitator Superfamily
IMBHKMNO_02323 9.49e-98 yxaI - - S - - - membrane protein domain
IMBHKMNO_02324 1.61e-154 - - - E - - - Ring-cleavage extradiol dioxygenase
IMBHKMNO_02325 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IMBHKMNO_02326 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IMBHKMNO_02327 1.88e-290 - - - S - - - Fic/DOC family
IMBHKMNO_02328 3.04e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_02329 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IMBHKMNO_02330 3.87e-111 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IMBHKMNO_02331 2.23e-196 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IMBHKMNO_02332 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IMBHKMNO_02333 5.68e-114 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IMBHKMNO_02334 3.43e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMBHKMNO_02335 1.4e-237 - - - S - - - Fusaric acid resistance protein-like
IMBHKMNO_02336 1.31e-26 - - - - - - - -
IMBHKMNO_02337 0.0 - - - L - - - AAA domain
IMBHKMNO_02338 8.46e-228 - - - S - - - Protein of unknown function DUF262
IMBHKMNO_02339 2.97e-178 - - - S - - - FRG
IMBHKMNO_02340 8.3e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMBHKMNO_02343 3.99e-278 yycP - - - - - - -
IMBHKMNO_02344 6.08e-172 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IMBHKMNO_02345 2.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IMBHKMNO_02346 2.05e-113 yycN - - K - - - Acetyltransferase
IMBHKMNO_02348 5.26e-259 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IMBHKMNO_02349 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IMBHKMNO_02350 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IMBHKMNO_02351 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IMBHKMNO_02352 3.41e-83 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IMBHKMNO_02353 2.69e-57 sdpR - - K - - - transcriptional
IMBHKMNO_02354 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IMBHKMNO_02355 3.07e-187 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
IMBHKMNO_02356 0.0 - - - S - - - ABC transporter
IMBHKMNO_02357 4.98e-256 - - - S - - - Major Facilitator Superfamily
IMBHKMNO_02358 0.0 - - - - - - - -
IMBHKMNO_02359 5.2e-240 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
IMBHKMNO_02360 6.16e-316 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IMBHKMNO_02361 1.17e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
IMBHKMNO_02362 5.3e-83 - - - S - - - Peptidase propeptide and YPEB domain
IMBHKMNO_02363 7.73e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMBHKMNO_02364 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IMBHKMNO_02365 1.14e-193 yycI - - S - - - protein conserved in bacteria
IMBHKMNO_02366 0.0 yycH - - S - - - protein conserved in bacteria
IMBHKMNO_02367 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_02368 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_02373 8.99e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMBHKMNO_02374 4.5e-94 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_02375 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IMBHKMNO_02376 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IMBHKMNO_02378 5.12e-25 yycC - - K - - - YycC-like protein
IMBHKMNO_02379 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IMBHKMNO_02380 4.72e-301 - - - M - - - Glycosyltransferase Family 4
IMBHKMNO_02381 3.3e-261 - - - S - - - Ecdysteroid kinase
IMBHKMNO_02382 3.96e-298 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
IMBHKMNO_02383 1.91e-298 - - - M - - - Glycosyltransferase Family 4
IMBHKMNO_02384 1.46e-155 - - - S - - - GlcNAc-PI de-N-acetylase
IMBHKMNO_02385 8.29e-115 - - - KLT - - - COG0515 Serine threonine protein kinase
IMBHKMNO_02386 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IMBHKMNO_02387 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IMBHKMNO_02388 1.01e-203 yybS - - S - - - membrane
IMBHKMNO_02390 2.74e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
IMBHKMNO_02391 4.56e-87 yybR - - K - - - Transcriptional regulator
IMBHKMNO_02392 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IMBHKMNO_02393 1.69e-211 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IMBHKMNO_02394 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IMBHKMNO_02395 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IMBHKMNO_02396 2.4e-152 - - - K - - - FCD domain
IMBHKMNO_02397 1.58e-116 - - - S - - - PFAM DinB family protein
IMBHKMNO_02398 3.86e-203 - - - G - - - Major Facilitator Superfamily
IMBHKMNO_02400 2.01e-71 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IMBHKMNO_02401 4.87e-148 ydgI - - C - - - nitroreductase
IMBHKMNO_02402 6.79e-90 - - - K - - - Winged helix DNA-binding domain
IMBHKMNO_02403 1.38e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_02404 1.44e-99 yybA - - K - - - transcriptional
IMBHKMNO_02405 1.49e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
IMBHKMNO_02406 4.56e-209 - - - M - - - Domain of Unknown Function (DUF1259)
IMBHKMNO_02407 1.85e-28 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IMBHKMNO_02408 3.16e-61 - - - F - - - Belongs to the Nudix hydrolase family
IMBHKMNO_02409 3.4e-126 - - - - - - - -
IMBHKMNO_02410 1.33e-86 - - - S - - - Leucine-rich repeat (LRR) protein
IMBHKMNO_02412 4.04e-82 - - - O - - - Subtilase family
IMBHKMNO_02413 3.88e-315 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMBHKMNO_02414 3.69e-164 - - - EG - - - EamA-like transporter family
IMBHKMNO_02415 1.6e-154 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IMBHKMNO_02417 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IMBHKMNO_02418 2.96e-210 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IMBHKMNO_02419 3e-315 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
IMBHKMNO_02420 3.3e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_02421 1.19e-232 ccpB - - K - - - Transcriptional regulator
IMBHKMNO_02422 2.41e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IMBHKMNO_02423 1.61e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMBHKMNO_02424 1.04e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IMBHKMNO_02425 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMBHKMNO_02426 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMBHKMNO_02427 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IMBHKMNO_02428 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IMBHKMNO_02429 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMBHKMNO_02430 7.41e-45 yyzM - - S - - - protein conserved in bacteria
IMBHKMNO_02431 1.94e-224 yyaD - - S - - - Membrane
IMBHKMNO_02432 2e-143 yyaC - - S - - - Sporulation protein YyaC
IMBHKMNO_02433 3.36e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IMBHKMNO_02434 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IMBHKMNO_02435 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IMBHKMNO_02436 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IMBHKMNO_02437 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IMBHKMNO_02438 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMBHKMNO_02439 2.21e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IMBHKMNO_02440 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMBHKMNO_02441 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IMBHKMNO_02442 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMBHKMNO_02443 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IMBHKMNO_02444 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IMBHKMNO_02445 1.3e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMBHKMNO_02446 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
IMBHKMNO_02447 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMBHKMNO_02448 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMBHKMNO_02452 1.5e-277 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IMBHKMNO_02453 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMBHKMNO_02454 1.1e-230 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
IMBHKMNO_02455 6.88e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IMBHKMNO_02456 3.89e-288 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IMBHKMNO_02457 7.62e-223 ybaS - - S - - - Na -dependent transporter
IMBHKMNO_02458 1.51e-140 ybbA - - S ko:K07017 - ko00000 Putative esterase
IMBHKMNO_02459 1.37e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02460 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02461 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IMBHKMNO_02462 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IMBHKMNO_02463 5.49e-301 ybbC - - S - - - protein conserved in bacteria
IMBHKMNO_02464 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IMBHKMNO_02465 1.13e-311 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IMBHKMNO_02466 1.96e-308 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_02467 2.32e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IMBHKMNO_02468 6.11e-111 ybbJ - - J - - - acetyltransferase
IMBHKMNO_02469 2.63e-99 ybbK - - S - - - Protein of unknown function (DUF523)
IMBHKMNO_02475 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_02476 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IMBHKMNO_02477 1.28e-187 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMBHKMNO_02478 7.52e-293 ybbR - - S - - - protein conserved in bacteria
IMBHKMNO_02479 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMBHKMNO_02480 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IMBHKMNO_02482 0.0 - - - K - - - SIR2-like domain
IMBHKMNO_02483 5.87e-197 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IMBHKMNO_02484 3.24e-138 - - - S - - - ABC-2 family transporter protein
IMBHKMNO_02485 1.89e-123 ybdN - - - - - - -
IMBHKMNO_02486 5.83e-166 ybdO - - S - - - Domain of unknown function (DUF4885)
IMBHKMNO_02487 1.21e-205 dkgB - - S - - - Aldo/keto reductase family
IMBHKMNO_02488 4.26e-135 yxaC - - M - - - effector of murein hydrolase
IMBHKMNO_02489 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IMBHKMNO_02490 3.95e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_02492 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_02493 2.64e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IMBHKMNO_02494 1.57e-258 - - - T - - - COG4585 Signal transduction histidine kinase
IMBHKMNO_02495 1.18e-140 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IMBHKMNO_02496 6.21e-214 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IMBHKMNO_02497 3.7e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IMBHKMNO_02498 2.18e-251 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IMBHKMNO_02499 9.56e-35 - - - - - - - -
IMBHKMNO_02500 8.99e-104 - - - S - - - Domain of unknown function (DUF4879)
IMBHKMNO_02501 6.87e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IMBHKMNO_02502 3.42e-142 yqeB - - - - - - -
IMBHKMNO_02503 7.84e-55 ybyB - - - - - - -
IMBHKMNO_02504 0.0 ybeC - - E - - - amino acid
IMBHKMNO_02507 8.36e-54 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IMBHKMNO_02508 3.88e-67 - - - - - - - -
IMBHKMNO_02509 7.3e-22 - - - S - - - Protein of unknown function (DUF2651)
IMBHKMNO_02510 4.23e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IMBHKMNO_02511 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IMBHKMNO_02512 2.36e-22 - - - S - - - Protein of unknown function (DUF2651)
IMBHKMNO_02513 2.02e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IMBHKMNO_02515 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IMBHKMNO_02516 2.44e-45 - - - - - - - -
IMBHKMNO_02517 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
IMBHKMNO_02518 1.5e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IMBHKMNO_02519 1.32e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IMBHKMNO_02520 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMBHKMNO_02521 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
IMBHKMNO_02522 1.24e-193 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IMBHKMNO_02523 8.67e-55 ybfN - - - - - - -
IMBHKMNO_02524 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IMBHKMNO_02525 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IMBHKMNO_02526 1.18e-254 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IMBHKMNO_02527 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IMBHKMNO_02528 6.14e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IMBHKMNO_02529 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IMBHKMNO_02530 6.45e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IMBHKMNO_02531 4.59e-281 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_02532 1.94e-219 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IMBHKMNO_02533 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IMBHKMNO_02534 2.83e-48 - - - L - - - Transposase
IMBHKMNO_02535 4.47e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMBHKMNO_02536 8.46e-146 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IMBHKMNO_02537 9.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IMBHKMNO_02538 9.37e-83 ydfP - - S ko:K15977 - ko00000 DoxX
IMBHKMNO_02539 1.32e-74 ydfQ - - CO - - - Thioredoxin
IMBHKMNO_02540 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
IMBHKMNO_02541 4.29e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IMBHKMNO_02542 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IMBHKMNO_02543 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IMBHKMNO_02544 4.95e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMBHKMNO_02545 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IMBHKMNO_02546 1.21e-266 ycbU - - E - - - Selenocysteine lyase
IMBHKMNO_02547 2.29e-309 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IMBHKMNO_02548 8.93e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IMBHKMNO_02549 6.56e-253 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IMBHKMNO_02550 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IMBHKMNO_02551 1.61e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
IMBHKMNO_02552 1.79e-217 yccK - - C - - - Aldo keto reductase
IMBHKMNO_02553 1.13e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
IMBHKMNO_02554 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_02555 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_02556 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IMBHKMNO_02557 9.98e-249 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IMBHKMNO_02558 4.28e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IMBHKMNO_02559 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IMBHKMNO_02560 7.35e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IMBHKMNO_02561 5.69e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IMBHKMNO_02562 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IMBHKMNO_02563 8.1e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_02564 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IMBHKMNO_02565 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IMBHKMNO_02566 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IMBHKMNO_02567 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IMBHKMNO_02568 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IMBHKMNO_02569 1.17e-246 yceH - - P - - - Belongs to the TelA family
IMBHKMNO_02570 6.09e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IMBHKMNO_02571 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IMBHKMNO_02572 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IMBHKMNO_02573 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IMBHKMNO_02574 3.37e-272 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IMBHKMNO_02575 3.27e-293 ycgA - - S - - - Membrane
IMBHKMNO_02576 7.63e-107 ycgB - - - - - - -
IMBHKMNO_02577 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IMBHKMNO_02578 6.6e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IMBHKMNO_02579 0.0 mdr - - EGP - - - the major facilitator superfamily
IMBHKMNO_02580 2.82e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_02581 3.18e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
IMBHKMNO_02582 6.95e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IMBHKMNO_02583 9.42e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_02584 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IMBHKMNO_02585 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IMBHKMNO_02586 2.04e-150 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
IMBHKMNO_02587 2.04e-66 - - - L - - - transposase activity
IMBHKMNO_02588 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
IMBHKMNO_02589 7.55e-138 tmrB - - S - - - AAA domain
IMBHKMNO_02590 1.34e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
IMBHKMNO_02591 3.2e-302 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_02592 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMBHKMNO_02593 6.92e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IMBHKMNO_02594 2.47e-103 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IMBHKMNO_02595 4.3e-48 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IMBHKMNO_02596 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IMBHKMNO_02597 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IMBHKMNO_02598 5.44e-312 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMBHKMNO_02599 8.26e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IMBHKMNO_02600 2.62e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IMBHKMNO_02601 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IMBHKMNO_02602 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IMBHKMNO_02603 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMBHKMNO_02604 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMBHKMNO_02605 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IMBHKMNO_02606 2.01e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IMBHKMNO_02607 6.75e-288 yciC - - S - - - GTPases (G3E family)
IMBHKMNO_02608 8.73e-282 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IMBHKMNO_02609 6.3e-95 yckC - - S - - - membrane
IMBHKMNO_02610 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
IMBHKMNO_02611 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMBHKMNO_02612 5.81e-92 nin - - S - - - Competence protein J (ComJ)
IMBHKMNO_02613 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
IMBHKMNO_02614 5.17e-123 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IMBHKMNO_02615 3.14e-139 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IMBHKMNO_02616 4.1e-84 hxlR - - K - - - transcriptional
IMBHKMNO_02617 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_02618 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMBHKMNO_02619 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IMBHKMNO_02620 2.41e-177 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IMBHKMNO_02621 9.53e-317 - - - E - - - Aminotransferase class I and II
IMBHKMNO_02622 4.34e-166 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IMBHKMNO_02623 8.56e-142 yczE - - S ko:K07149 - ko00000 membrane
IMBHKMNO_02624 7.96e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IMBHKMNO_02625 3.03e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IMBHKMNO_02626 2.3e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IMBHKMNO_02627 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IMBHKMNO_02628 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IMBHKMNO_02629 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IMBHKMNO_02630 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IMBHKMNO_02631 1.67e-100 yclD - - - - - - -
IMBHKMNO_02632 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IMBHKMNO_02633 0.0 yclG - - M - - - Pectate lyase superfamily protein
IMBHKMNO_02635 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IMBHKMNO_02636 3.29e-299 gerKC - - S ko:K06297 - ko00000 spore germination
IMBHKMNO_02637 2.27e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IMBHKMNO_02638 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMBHKMNO_02639 7.35e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMBHKMNO_02640 1.82e-182 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IMBHKMNO_02641 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IMBHKMNO_02642 1.87e-168 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02643 6.87e-277 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IMBHKMNO_02644 9.28e-317 yxeQ - - S - - - MmgE/PrpD family
IMBHKMNO_02645 2.21e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IMBHKMNO_02646 1.78e-304 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IMBHKMNO_02647 2.6e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMBHKMNO_02648 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
IMBHKMNO_02649 2.72e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_02651 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IMBHKMNO_02652 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02653 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02654 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02655 2.78e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IMBHKMNO_02656 7.02e-316 ycnB - - EGP - - - the major facilitator superfamily
IMBHKMNO_02657 3.67e-196 ycnC - - K - - - Transcriptional regulator
IMBHKMNO_02658 2.39e-175 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
IMBHKMNO_02659 5.64e-59 ycnE - - S - - - Monooxygenase
IMBHKMNO_02660 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IMBHKMNO_02661 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMBHKMNO_02662 1.53e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMBHKMNO_02663 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IMBHKMNO_02664 1.17e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IMBHKMNO_02665 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_02666 2.05e-131 ycnI - - S - - - protein conserved in bacteria
IMBHKMNO_02667 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IMBHKMNO_02668 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IMBHKMNO_02669 9.6e-73 - - - - - - - -
IMBHKMNO_02670 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IMBHKMNO_02671 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IMBHKMNO_02672 4.71e-263 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IMBHKMNO_02673 1.38e-85 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IMBHKMNO_02675 1.34e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IMBHKMNO_02676 2.49e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IMBHKMNO_02677 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IMBHKMNO_02678 3.29e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IMBHKMNO_02679 3.83e-174 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IMBHKMNO_02680 1.03e-241 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IMBHKMNO_02681 1.39e-168 kipR - - K - - - Transcriptional regulator
IMBHKMNO_02682 2.71e-150 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IMBHKMNO_02684 5.95e-75 yczJ - - S - - - biosynthesis
IMBHKMNO_02685 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IMBHKMNO_02686 5.18e-221 ycsN - - S - - - Oxidoreductase
IMBHKMNO_02687 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IMBHKMNO_02688 0.0 ydaB - - IQ - - - acyl-CoA ligase
IMBHKMNO_02689 3.82e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_02690 6.5e-124 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IMBHKMNO_02691 2.24e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMBHKMNO_02692 3.69e-101 ydaG - - S - - - general stress protein
IMBHKMNO_02693 6.24e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IMBHKMNO_02694 7.65e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IMBHKMNO_02695 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IMBHKMNO_02696 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMBHKMNO_02697 1.11e-245 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IMBHKMNO_02698 5.39e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IMBHKMNO_02699 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IMBHKMNO_02700 6.45e-303 ydaM - - M - - - Glycosyl transferase family group 2
IMBHKMNO_02701 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IMBHKMNO_02702 0.0 ydaO - - E - - - amino acid
IMBHKMNO_02703 1.21e-94 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IMBHKMNO_02704 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IMBHKMNO_02705 8.45e-65 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IMBHKMNO_02706 1.88e-60 - - - V - - - HNH endonuclease
IMBHKMNO_02707 7.56e-116 yokH - - G - - - SMI1 / KNR4 family
IMBHKMNO_02708 7.03e-34 - - - - - - - -
IMBHKMNO_02709 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IMBHKMNO_02711 2e-07 - - - - - - - -
IMBHKMNO_02713 6.95e-112 - - - - - - - -
IMBHKMNO_02714 4.31e-131 - - - - - - - -
IMBHKMNO_02715 2.14e-53 - - - - - - - -
IMBHKMNO_02716 1.08e-287 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IMBHKMNO_02718 1.95e-45 ydaT - - - - - - -
IMBHKMNO_02719 2.54e-92 yvaD - - S - - - Family of unknown function (DUF5360)
IMBHKMNO_02720 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IMBHKMNO_02721 2.29e-183 ydbA - - P - - - EcsC protein family
IMBHKMNO_02722 3.48e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
IMBHKMNO_02723 7.98e-86 ydbB - - G - - - Cupin domain
IMBHKMNO_02724 8.65e-81 ydbC - - S - - - Domain of unknown function (DUF4937
IMBHKMNO_02725 1.11e-197 ydbD - - P ko:K07217 - ko00000 Catalase
IMBHKMNO_02726 1.89e-255 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IMBHKMNO_02727 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IMBHKMNO_02728 1.5e-152 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IMBHKMNO_02729 3.21e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IMBHKMNO_02730 8.61e-231 ydbI - - S - - - AI-2E family transporter
IMBHKMNO_02731 7.94e-220 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_02732 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IMBHKMNO_02733 2.29e-70 ydbL - - - - - - -
IMBHKMNO_02734 6.02e-260 ydbM - - I - - - acyl-CoA dehydrogenase
IMBHKMNO_02735 1.13e-15 - - - S - - - Fur-regulated basic protein B
IMBHKMNO_02736 6.58e-14 - - - S - - - Fur-regulated basic protein A
IMBHKMNO_02737 6.99e-161 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMBHKMNO_02738 2.25e-74 ydbP - - CO - - - Thioredoxin
IMBHKMNO_02739 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IMBHKMNO_02740 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IMBHKMNO_02741 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IMBHKMNO_02742 6.24e-96 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IMBHKMNO_02743 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IMBHKMNO_02744 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IMBHKMNO_02745 1.54e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IMBHKMNO_02746 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IMBHKMNO_02747 1.98e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMBHKMNO_02748 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IMBHKMNO_02749 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IMBHKMNO_02750 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IMBHKMNO_02751 6.28e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IMBHKMNO_02752 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IMBHKMNO_02753 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IMBHKMNO_02754 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IMBHKMNO_02755 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IMBHKMNO_02756 3.8e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_02757 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IMBHKMNO_02758 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IMBHKMNO_02759 1.78e-21 - - - - - - - -
IMBHKMNO_02760 4.27e-76 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IMBHKMNO_02768 1.86e-246 ydcL - - L - - - Belongs to the 'phage' integrase family
IMBHKMNO_02769 6.44e-71 - - - E - - - IrrE N-terminal-like domain
IMBHKMNO_02770 9.15e-58 - - - K - - - Transcriptional
IMBHKMNO_02771 3.22e-19 - - - - - - - -
IMBHKMNO_02773 1.61e-51 - - - S - - - Bacterial protein of unknown function (DUF961)
IMBHKMNO_02775 1.34e-303 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
IMBHKMNO_02776 5.14e-215 nicK - - L ko:K07467 - ko00000 Replication initiation factor
IMBHKMNO_02781 7.07e-53 yddA - - - - - - -
IMBHKMNO_02783 1.05e-164 yddB - - S - - - Conjugative transposon protein TcpC
IMBHKMNO_02784 2.72e-33 yddC - - - - - - -
IMBHKMNO_02785 1.85e-97 yddD - - S - - - TcpE family
IMBHKMNO_02786 0.0 yddE - - S - - - AAA-like domain
IMBHKMNO_02787 3.52e-50 - - - S - - - Domain of unknown function (DUF1874)
IMBHKMNO_02788 6.78e-258 yddG - - S - - - maturation of SSU-rRNA
IMBHKMNO_02789 3.59e-201 yddH - - M - - - Lysozyme-like
IMBHKMNO_02790 1.33e-73 yddI - - - - - - -
IMBHKMNO_02791 6.17e-48 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IMBHKMNO_02792 1.72e-171 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IMBHKMNO_02793 2.45e-150 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IMBHKMNO_02794 7.36e-200 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMBHKMNO_02795 1.86e-46 - - - K - - - MarR family
IMBHKMNO_02796 1.4e-96 - - - EG ko:K03298 - ko00000,ko02000 spore germination
IMBHKMNO_02797 1.54e-195 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_02798 1.09e-75 - - - K - - - Transcriptional regulator
IMBHKMNO_02800 1.03e-91 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IMBHKMNO_02804 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
IMBHKMNO_02805 1.61e-107 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IMBHKMNO_02806 5.23e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IMBHKMNO_02807 3.46e-84 - - - S - - - YjbR
IMBHKMNO_02808 3.35e-96 ywnA - - K - - - Transcriptional regulator
IMBHKMNO_02809 1.34e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IMBHKMNO_02810 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IMBHKMNO_02811 3.43e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IMBHKMNO_02812 1.53e-52 yrkD - - S - - - protein conserved in bacteria
IMBHKMNO_02813 5.61e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IMBHKMNO_02814 1.42e-76 - - - P - - - Rhodanese Homology Domain
IMBHKMNO_02815 1.59e-121 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IMBHKMNO_02816 2.27e-251 yrkH - - P - - - Rhodanese Homology Domain
IMBHKMNO_02817 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IMBHKMNO_02818 1.25e-166 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IMBHKMNO_02819 2.49e-157 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IMBHKMNO_02820 7.92e-129 - - - S - - - Protein of unknown function (DUF2812)
IMBHKMNO_02821 6.75e-67 - - - K - - - Transcriptional regulator PadR-like family
IMBHKMNO_02822 3.42e-232 - - - S - - - Patatin-like phospholipase
IMBHKMNO_02823 5.2e-103 - - - S - - - DinB superfamily
IMBHKMNO_02824 3.39e-146 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
IMBHKMNO_02825 4.08e-85 - - - K - - - COG1802 Transcriptional regulators
IMBHKMNO_02826 7.37e-51 - - - J - - - Endoribonuclease L-PSP
IMBHKMNO_02827 1.98e-177 - - - E ko:K03837 - ko00000,ko02000 Serine transporter
IMBHKMNO_02828 2.03e-204 - - - E - - - Peptidase dimerisation domain
IMBHKMNO_02829 1.63e-160 - - - K - - - helix_turn_helix, arabinose operon control protein
IMBHKMNO_02830 1.41e-221 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IMBHKMNO_02831 2.9e-295 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMBHKMNO_02832 2.17e-242 ydeG - - EGP - - - Major facilitator superfamily
IMBHKMNO_02833 2.86e-16 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IMBHKMNO_02834 1.41e-43 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IMBHKMNO_02836 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IMBHKMNO_02837 1.77e-102 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_02838 1.11e-212 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IMBHKMNO_02839 1.5e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IMBHKMNO_02841 7.47e-128 yrkC - - G - - - Cupin domain
IMBHKMNO_02842 4.57e-111 ykkA - - S - - - Protein of unknown function (DUF664)
IMBHKMNO_02843 5.69e-191 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
IMBHKMNO_02845 2.56e-248 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IMBHKMNO_02846 2.4e-68 ydeH - - - - - - -
IMBHKMNO_02847 2.69e-208 - - - S - - - Sodium Bile acid symporter family
IMBHKMNO_02848 3.68e-257 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IMBHKMNO_02849 2.97e-86 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IMBHKMNO_02850 1.2e-282 nhaC_1 - - C - - - antiporter
IMBHKMNO_02851 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IMBHKMNO_02852 7.24e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_02854 4.35e-250 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IMBHKMNO_02855 2.43e-132 ydeS - - K - - - Transcriptional regulator
IMBHKMNO_02856 9.33e-135 ydeK - - EG - - - -transporter
IMBHKMNO_02857 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMBHKMNO_02858 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
IMBHKMNO_02859 4.71e-34 yraE - - - ko:K06440 - ko00000 -
IMBHKMNO_02860 2.5e-281 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IMBHKMNO_02861 1.66e-84 yraF - - M - - - Spore coat protein
IMBHKMNO_02862 4.19e-50 yraG - - - ko:K06440 - ko00000 -
IMBHKMNO_02863 8.97e-136 - - - G - - - Major Facilitator Superfamily
IMBHKMNO_02864 2.54e-94 - - - GK - - - Transcriptional regulator
IMBHKMNO_02865 7.65e-28 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
IMBHKMNO_02866 3.23e-08 - - - S - - - Hexapeptide repeat of succinyl-transferase
IMBHKMNO_02867 9.49e-273 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_02868 3.99e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_02869 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IMBHKMNO_02870 2.8e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
IMBHKMNO_02871 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IMBHKMNO_02872 9.11e-128 ynaD - - J - - - Acetyltransferase (GNAT) domain
IMBHKMNO_02873 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_02874 6.59e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IMBHKMNO_02875 9.58e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IMBHKMNO_02876 1.17e-289 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMBHKMNO_02877 2.24e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
IMBHKMNO_02878 3.01e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IMBHKMNO_02879 7.52e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IMBHKMNO_02880 7.18e-194 bltR - - K - - - helix_turn_helix, mercury resistance
IMBHKMNO_02881 7.33e-191 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IMBHKMNO_02882 1.16e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IMBHKMNO_02883 7.76e-187 - - - Q - - - ubiE/COQ5 methyltransferase family
IMBHKMNO_02884 7.19e-211 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
IMBHKMNO_02885 1.88e-153 ydhC - - K - - - FCD
IMBHKMNO_02886 4.77e-291 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IMBHKMNO_02889 0.0 pbpE - - V - - - Beta-lactamase
IMBHKMNO_02891 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
IMBHKMNO_02892 9.11e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IMBHKMNO_02893 4.15e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IMBHKMNO_02894 3.64e-151 - - - K ko:K05799 - ko00000,ko03000 FCD
IMBHKMNO_02895 1.68e-274 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IMBHKMNO_02896 2.46e-64 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IMBHKMNO_02897 3.69e-66 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IMBHKMNO_02898 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
IMBHKMNO_02899 0.0 ybeC - - E - - - amino acid
IMBHKMNO_02900 4.94e-211 ydhU - - P ko:K07217 - ko00000 Catalase
IMBHKMNO_02901 2.93e-112 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IMBHKMNO_02902 3.3e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IMBHKMNO_02903 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IMBHKMNO_02924 0.0 - - - S - - - peptidoglycan catabolic process
IMBHKMNO_02925 7.17e-108 - - - S - - - Phage tail protein
IMBHKMNO_02926 0.0 - - - S - - - Pfam Transposase IS66
IMBHKMNO_02928 1.81e-132 - - - - - - - -
IMBHKMNO_02929 0.0 - - - M - - - Pectate lyase superfamily protein
IMBHKMNO_02930 8e-100 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IMBHKMNO_02932 7.46e-45 - - - S - - - Bacteriophage holin
IMBHKMNO_02934 3.76e-07 - - - - - - - -
IMBHKMNO_02935 1e-271 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_02936 1.3e-284 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMBHKMNO_02937 7.65e-55 - - - S - - - YolD-like protein
IMBHKMNO_02938 2.8e-160 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IMBHKMNO_02940 7.6e-113 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
IMBHKMNO_02941 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IMBHKMNO_02942 4.55e-209 - - - V - - - HNH endonuclease
IMBHKMNO_02943 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
IMBHKMNO_02944 1.7e-112 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IMBHKMNO_02945 2.45e-122 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IMBHKMNO_02946 2.64e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IMBHKMNO_02947 7.49e-142 ymaB - - S - - - MutT family
IMBHKMNO_02948 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_02949 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMBHKMNO_02950 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IMBHKMNO_02951 9.42e-29 ymzA - - - - - - -
IMBHKMNO_02952 9.98e-58 - - - - - - - -
IMBHKMNO_02953 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IMBHKMNO_02954 8.91e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMBHKMNO_02955 5.96e-77 ymaF - - S - - - YmaF family
IMBHKMNO_02957 1e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IMBHKMNO_02958 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IMBHKMNO_02959 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IMBHKMNO_02960 1.61e-162 ymaC - - S - - - Replication protein
IMBHKMNO_02961 6.08e-06 - - - - - - - -
IMBHKMNO_02962 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IMBHKMNO_02963 2.78e-82 ymzB - - - - - - -
IMBHKMNO_02964 4.27e-151 yoaK - - S - - - Membrane
IMBHKMNO_02965 1.01e-100 nucB - - M - - - Deoxyribonuclease NucA/NucB
IMBHKMNO_02966 5.61e-293 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IMBHKMNO_02967 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IMBHKMNO_02968 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IMBHKMNO_02969 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_02970 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_02971 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IMBHKMNO_02972 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IMBHKMNO_02973 1.51e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IMBHKMNO_02974 1.21e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IMBHKMNO_02975 2.51e-47 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IMBHKMNO_02976 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_02977 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IMBHKMNO_02978 1.65e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_02979 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IMBHKMNO_02983 2.3e-29 - - - - - - - -
IMBHKMNO_02984 8.88e-50 - - - L - - - Phage integrase family
IMBHKMNO_02985 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMBHKMNO_02986 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMBHKMNO_02987 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IMBHKMNO_02988 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IMBHKMNO_02989 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMBHKMNO_02990 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IMBHKMNO_02991 5.6e-249 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IMBHKMNO_02992 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IMBHKMNO_02993 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IMBHKMNO_02994 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IMBHKMNO_02995 3.38e-273 pbpX - - V - - - Beta-lactamase
IMBHKMNO_02996 6.17e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMBHKMNO_02997 1.33e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IMBHKMNO_02998 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMBHKMNO_02999 5.51e-175 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IMBHKMNO_03000 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IMBHKMNO_03001 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
IMBHKMNO_03002 2.88e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IMBHKMNO_03003 4.1e-310 ymfH - - S - - - zinc protease
IMBHKMNO_03004 1.12e-306 albE - - S - - - Peptidase M16
IMBHKMNO_03005 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IMBHKMNO_03006 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_03007 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_03008 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03009 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IMBHKMNO_03010 6.32e-42 - - - S - - - YlzJ-like protein
IMBHKMNO_03011 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IMBHKMNO_03012 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMBHKMNO_03013 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMBHKMNO_03014 1.15e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IMBHKMNO_03015 1e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMBHKMNO_03016 3.9e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IMBHKMNO_03017 1.91e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IMBHKMNO_03018 2.17e-56 ymxH - - S - - - YlmC YmxH family
IMBHKMNO_03019 4.85e-298 mlpA - - S - - - Belongs to the peptidase M16 family
IMBHKMNO_03020 1.19e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IMBHKMNO_03021 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IMBHKMNO_03022 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMBHKMNO_03023 7.46e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IMBHKMNO_03024 1.48e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMBHKMNO_03025 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMBHKMNO_03026 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IMBHKMNO_03027 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMBHKMNO_03028 6.16e-63 ylxQ - - J - - - ribosomal protein
IMBHKMNO_03029 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IMBHKMNO_03030 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IMBHKMNO_03031 3.28e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IMBHKMNO_03032 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMBHKMNO_03033 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IMBHKMNO_03034 4.66e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IMBHKMNO_03035 7.68e-274 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IMBHKMNO_03036 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IMBHKMNO_03037 4.49e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMBHKMNO_03038 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IMBHKMNO_03039 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IMBHKMNO_03040 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMBHKMNO_03041 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IMBHKMNO_03042 1.68e-93 ylxL - - - - - - -
IMBHKMNO_03043 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_03044 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IMBHKMNO_03045 5.91e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IMBHKMNO_03046 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IMBHKMNO_03047 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IMBHKMNO_03048 2.02e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IMBHKMNO_03049 1.05e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IMBHKMNO_03050 3.77e-248 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IMBHKMNO_03051 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMBHKMNO_03052 1.03e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMBHKMNO_03053 6.69e-167 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IMBHKMNO_03054 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IMBHKMNO_03055 1.73e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IMBHKMNO_03056 5.4e-143 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IMBHKMNO_03057 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IMBHKMNO_03058 2.84e-246 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMBHKMNO_03059 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IMBHKMNO_03060 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IMBHKMNO_03061 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IMBHKMNO_03062 5.15e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IMBHKMNO_03063 1.28e-261 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IMBHKMNO_03064 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
IMBHKMNO_03065 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IMBHKMNO_03066 1.05e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IMBHKMNO_03067 1.13e-121 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IMBHKMNO_03068 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IMBHKMNO_03069 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IMBHKMNO_03070 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IMBHKMNO_03071 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IMBHKMNO_03072 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IMBHKMNO_03073 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMBHKMNO_03074 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMBHKMNO_03075 6.07e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMBHKMNO_03076 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IMBHKMNO_03077 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMBHKMNO_03078 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMBHKMNO_03079 5.15e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IMBHKMNO_03080 2.17e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMBHKMNO_03081 2.36e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IMBHKMNO_03082 4.88e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IMBHKMNO_03083 0.0 ylqG - - - - - - -
IMBHKMNO_03084 2.38e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMBHKMNO_03085 7.24e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMBHKMNO_03086 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IMBHKMNO_03087 9.8e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IMBHKMNO_03088 6.16e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMBHKMNO_03089 3.41e-80 ylqD - - S - - - YlqD protein
IMBHKMNO_03090 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IMBHKMNO_03091 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IMBHKMNO_03092 3.46e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMBHKMNO_03093 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMBHKMNO_03094 4.31e-182 - - - S - - - Phosphotransferase enzyme family
IMBHKMNO_03095 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IMBHKMNO_03096 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IMBHKMNO_03097 1.23e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IMBHKMNO_03098 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMBHKMNO_03099 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IMBHKMNO_03100 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_03101 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IMBHKMNO_03102 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IMBHKMNO_03103 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMBHKMNO_03104 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IMBHKMNO_03105 1.19e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IMBHKMNO_03106 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IMBHKMNO_03107 3.65e-78 yloU - - S - - - protein conserved in bacteria
IMBHKMNO_03108 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IMBHKMNO_03109 6.42e-154 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IMBHKMNO_03110 1.19e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IMBHKMNO_03111 2.96e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IMBHKMNO_03112 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IMBHKMNO_03113 5.82e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IMBHKMNO_03114 1.25e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IMBHKMNO_03115 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMBHKMNO_03116 4.56e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMBHKMNO_03117 2.04e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IMBHKMNO_03118 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMBHKMNO_03119 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMBHKMNO_03120 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IMBHKMNO_03121 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IMBHKMNO_03122 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IMBHKMNO_03123 2.14e-198 yloC - - S - - - stress-induced protein
IMBHKMNO_03124 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IMBHKMNO_03125 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IMBHKMNO_03126 2.19e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IMBHKMNO_03127 5.05e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IMBHKMNO_03128 2.4e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IMBHKMNO_03129 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IMBHKMNO_03130 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IMBHKMNO_03131 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IMBHKMNO_03132 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IMBHKMNO_03134 7.37e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMBHKMNO_03135 1.74e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IMBHKMNO_03136 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IMBHKMNO_03137 2.05e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IMBHKMNO_03138 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IMBHKMNO_03139 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IMBHKMNO_03140 5.44e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IMBHKMNO_03141 1.21e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IMBHKMNO_03142 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IMBHKMNO_03143 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMBHKMNO_03144 1.04e-213 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IMBHKMNO_03145 1.02e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMBHKMNO_03146 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
IMBHKMNO_03147 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMBHKMNO_03148 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IMBHKMNO_03149 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
IMBHKMNO_03150 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IMBHKMNO_03151 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IMBHKMNO_03152 1.18e-157 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMBHKMNO_03153 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IMBHKMNO_03154 7.13e-52 ylmC - - S - - - sporulation protein
IMBHKMNO_03155 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IMBHKMNO_03156 1.97e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IMBHKMNO_03157 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_03158 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_03159 1.94e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IMBHKMNO_03160 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IMBHKMNO_03161 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMBHKMNO_03162 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IMBHKMNO_03163 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IMBHKMNO_03164 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IMBHKMNO_03165 1.34e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMBHKMNO_03166 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IMBHKMNO_03167 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMBHKMNO_03168 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMBHKMNO_03169 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMBHKMNO_03170 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IMBHKMNO_03171 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IMBHKMNO_03172 1.98e-67 ftsL - - D - - - Essential cell division protein
IMBHKMNO_03173 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IMBHKMNO_03174 3.7e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IMBHKMNO_03175 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IMBHKMNO_03176 6.57e-208 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMBHKMNO_03177 1.14e-116 ylbP - - K - - - n-acetyltransferase
IMBHKMNO_03178 8.95e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IMBHKMNO_03179 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IMBHKMNO_03180 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IMBHKMNO_03181 7.42e-295 ylbM - - S - - - Belongs to the UPF0348 family
IMBHKMNO_03182 5.31e-241 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IMBHKMNO_03183 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IMBHKMNO_03184 5.88e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IMBHKMNO_03185 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMBHKMNO_03186 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IMBHKMNO_03188 3.94e-57 ylbG - - S - - - UPF0298 protein
IMBHKMNO_03189 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
IMBHKMNO_03190 1.73e-48 ylbE - - S - - - YlbE-like protein
IMBHKMNO_03191 3.45e-86 ylbD - - S - - - Putative coat protein
IMBHKMNO_03192 5.41e-253 ylbC - - S - - - protein with SCP PR1 domains
IMBHKMNO_03193 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
IMBHKMNO_03194 4.12e-79 ylbA - - S - - - YugN-like family
IMBHKMNO_03195 8.82e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IMBHKMNO_03196 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IMBHKMNO_03197 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IMBHKMNO_03198 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMBHKMNO_03199 6.83e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IMBHKMNO_03200 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IMBHKMNO_03201 2.73e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IMBHKMNO_03202 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMBHKMNO_03203 2.02e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IMBHKMNO_03204 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
IMBHKMNO_03205 1.83e-151 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IMBHKMNO_03206 1.76e-86 - - - L ko:K06400 - ko00000 Recombinase zinc beta ribbon domain
IMBHKMNO_03215 3.93e-65 - - - - - - - -
IMBHKMNO_03216 2.04e-159 - - - KL - - - Phage plasmid primase P4 family
IMBHKMNO_03217 1.43e-224 - - - - - - - -
IMBHKMNO_03220 1.85e-52 - - - - - - - -
IMBHKMNO_03221 2.24e-15 - - - - - - - -
IMBHKMNO_03223 1.88e-71 - - - - - - - -
IMBHKMNO_03224 9.04e-65 - - - - - - - -
IMBHKMNO_03230 3.5e-27 - - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
IMBHKMNO_03231 3.58e-11 - - - S - - - endonuclease activity
IMBHKMNO_03234 5.65e-134 - - - S - - - peptidoglycan catabolic process
IMBHKMNO_03235 0.0 - - - S - - - peptidoglycan catabolic process
IMBHKMNO_03236 0.0 - - - S - - - Pfam Transposase IS66
IMBHKMNO_03238 4.27e-27 - - - - - - - -
IMBHKMNO_03239 2.15e-204 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IMBHKMNO_03241 1.37e-31 - - - S - - - Protein of unknown function (DUF1433)
IMBHKMNO_03242 3.26e-231 - - - I - - - Pfam Lipase (class 3)
IMBHKMNO_03243 2.17e-33 - - - - - - - -
IMBHKMNO_03244 2.74e-54 - - - - - - - -
IMBHKMNO_03246 3.32e-29 - - - K - - - Helix-turn-helix domain
IMBHKMNO_03248 2.47e-14 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03259 7.73e-60 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IMBHKMNO_03260 1.01e-109 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMBHKMNO_03261 1.82e-311 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IMBHKMNO_03262 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IMBHKMNO_03263 6.78e-46 ylaI - - S - - - protein conserved in bacteria
IMBHKMNO_03264 2.44e-65 - - - S - - - YlaH-like protein
IMBHKMNO_03265 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IMBHKMNO_03266 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
IMBHKMNO_03267 1.14e-61 ylaE - - - - - - -
IMBHKMNO_03269 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IMBHKMNO_03270 5.32e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
IMBHKMNO_03271 9.88e-197 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IMBHKMNO_03272 3.33e-33 ykzI - - - - - - -
IMBHKMNO_03273 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
IMBHKMNO_03274 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
IMBHKMNO_03275 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IMBHKMNO_03276 3.29e-191 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IMBHKMNO_03277 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IMBHKMNO_03278 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IMBHKMNO_03279 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMBHKMNO_03280 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IMBHKMNO_03281 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IMBHKMNO_03282 1.16e-267 - - - V - - - Beta-lactamase
IMBHKMNO_03283 0.0 - - - IQ - - - Phosphopantetheine attachment site
IMBHKMNO_03284 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_03285 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_03286 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_03287 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_03288 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
IMBHKMNO_03289 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IMBHKMNO_03290 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IMBHKMNO_03291 8.56e-133 ykyA - - L - - - Putative cell-wall binding lipoprotein
IMBHKMNO_03292 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IMBHKMNO_03293 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IMBHKMNO_03294 2.14e-187 ykrA - - S - - - hydrolases of the HAD superfamily
IMBHKMNO_03295 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
IMBHKMNO_03296 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMBHKMNO_03297 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMBHKMNO_03298 3.95e-147 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IMBHKMNO_03299 6.15e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IMBHKMNO_03300 2.39e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IMBHKMNO_03301 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IMBHKMNO_03302 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IMBHKMNO_03303 4.47e-18 - - - S - - - Uncharacterized protein YkpC
IMBHKMNO_03304 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IMBHKMNO_03305 6.24e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMBHKMNO_03306 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IMBHKMNO_03307 1.5e-49 ykoA - - - - - - -
IMBHKMNO_03308 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IMBHKMNO_03309 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IMBHKMNO_03310 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IMBHKMNO_03311 1.6e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03312 7.01e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IMBHKMNO_03313 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_03314 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMBHKMNO_03315 1.19e-142 yknW - - S - - - Yip1 domain
IMBHKMNO_03316 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IMBHKMNO_03317 1.69e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IMBHKMNO_03318 7.56e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IMBHKMNO_03319 9.69e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IMBHKMNO_03320 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IMBHKMNO_03321 3.89e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IMBHKMNO_03322 1.03e-217 yknT - - - ko:K06437 - ko00000 -
IMBHKMNO_03323 1.76e-125 rok - - K - - - Repressor of ComK
IMBHKMNO_03324 1.3e-100 ykuV - - CO - - - thiol-disulfide
IMBHKMNO_03325 1.73e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IMBHKMNO_03326 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
IMBHKMNO_03327 6.85e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IMBHKMNO_03328 1.67e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IMBHKMNO_03329 7.24e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
IMBHKMNO_03330 5.59e-219 ykuO - - - - - - -
IMBHKMNO_03331 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
IMBHKMNO_03332 1.32e-215 ccpC - - K - - - Transcriptional regulator
IMBHKMNO_03333 8.55e-99 ykuL - - S - - - CBS domain
IMBHKMNO_03334 3.09e-35 ykzF - - S - - - Antirepressor AbbA
IMBHKMNO_03335 1.52e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
IMBHKMNO_03336 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
IMBHKMNO_03337 1.82e-295 ykuI - - T - - - Diguanylate phosphodiesterase
IMBHKMNO_03339 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_03340 3.51e-195 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IMBHKMNO_03341 3.62e-116 ykuD - - S - - - protein conserved in bacteria
IMBHKMNO_03342 1.87e-307 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_03343 1.2e-106 ykyB - - S - - - YkyB-like protein
IMBHKMNO_03344 3.2e-212 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IMBHKMNO_03345 6.38e-15 - - - - - - - -
IMBHKMNO_03346 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IMBHKMNO_03347 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_03348 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IMBHKMNO_03349 2.78e-160 ykwD - - J - - - protein with SCP PR1 domains
IMBHKMNO_03350 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IMBHKMNO_03351 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IMBHKMNO_03352 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IMBHKMNO_03353 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03354 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMBHKMNO_03355 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IMBHKMNO_03356 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_03357 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IMBHKMNO_03358 2.03e-224 ykvZ - - K - - - Transcriptional regulator
IMBHKMNO_03360 4.71e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IMBHKMNO_03361 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IMBHKMNO_03362 1.22e-113 stoA - - CO - - - thiol-disulfide
IMBHKMNO_03363 7.63e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IMBHKMNO_03364 5.07e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IMBHKMNO_03365 1.45e-38 - - - - - - - -
IMBHKMNO_03366 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IMBHKMNO_03367 1.47e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
IMBHKMNO_03369 7.12e-204 - - - G - - - Glycosyl hydrolases family 18
IMBHKMNO_03370 1.26e-46 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
IMBHKMNO_03371 1.67e-269 - - - M - - - Glycosyl transferases group 1
IMBHKMNO_03372 2.38e-43 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IMBHKMNO_03373 3.65e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IMBHKMNO_03374 8.33e-80 ykvN - - K - - - Transcriptional regulator
IMBHKMNO_03375 3.1e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IMBHKMNO_03376 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IMBHKMNO_03377 1.26e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IMBHKMNO_03378 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IMBHKMNO_03379 8.19e-248 - - - - - - - -
IMBHKMNO_03380 1.73e-228 ykvI - - S - - - membrane
IMBHKMNO_03381 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IMBHKMNO_03382 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IMBHKMNO_03383 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IMBHKMNO_03384 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IMBHKMNO_03385 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IMBHKMNO_03387 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IMBHKMNO_03388 2.61e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IMBHKMNO_03389 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IMBHKMNO_03390 2.73e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IMBHKMNO_03391 1.8e-291 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IMBHKMNO_03392 6.67e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IMBHKMNO_03393 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IMBHKMNO_03394 2.57e-250 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMBHKMNO_03396 2.65e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMBHKMNO_03397 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_03398 4.36e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IMBHKMNO_03399 1.78e-31 ykzE - - - - - - -
IMBHKMNO_03400 3.35e-145 - - - S - - - Protein of unknown function (DUF421)
IMBHKMNO_03401 1.09e-307 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IMBHKMNO_03402 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IMBHKMNO_03403 1.62e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
IMBHKMNO_03404 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IMBHKMNO_03405 2.2e-231 ykrI - - S - - - Anti-sigma factor N-terminus
IMBHKMNO_03406 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMBHKMNO_03407 1.01e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IMBHKMNO_03408 7.92e-129 ykoX - - S - - - membrane-associated protein
IMBHKMNO_03409 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IMBHKMNO_03410 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IMBHKMNO_03411 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
IMBHKMNO_03412 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IMBHKMNO_03413 5.25e-37 ykoL - - - - - - -
IMBHKMNO_03414 1.11e-23 - - - - - - - -
IMBHKMNO_03415 1.01e-68 tnrA - - K - - - transcriptional
IMBHKMNO_03416 2.48e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IMBHKMNO_03418 3.79e-311 ydhD - - M - - - Glycosyl hydrolase
IMBHKMNO_03419 5.67e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IMBHKMNO_03420 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_03421 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IMBHKMNO_03422 3.01e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IMBHKMNO_03423 7.39e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IMBHKMNO_03424 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMBHKMNO_03425 1.91e-156 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IMBHKMNO_03426 9.79e-278 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_03427 2.04e-157 - - - K - - - Collagen triple helix repeat
IMBHKMNO_03428 1.37e-272 - - - M - - - Glycosyl transferase family 2
IMBHKMNO_03430 5.58e-78 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMBHKMNO_03431 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
IMBHKMNO_03432 7.24e-113 ohrR - - K - - - COG1846 Transcriptional regulators
IMBHKMNO_03433 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IMBHKMNO_03434 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMBHKMNO_03435 2.41e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMBHKMNO_03436 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IMBHKMNO_03437 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IMBHKMNO_03438 5.81e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IMBHKMNO_03439 6.11e-129 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMBHKMNO_03440 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
IMBHKMNO_03441 1.4e-202 ykgA - - E - - - Amidinotransferase
IMBHKMNO_03442 2.41e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IMBHKMNO_03443 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03444 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IMBHKMNO_03445 2.38e-252 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IMBHKMNO_03446 7.67e-224 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IMBHKMNO_03447 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IMBHKMNO_03448 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03449 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03450 2.8e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03451 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IMBHKMNO_03453 0.0 yubD - - P - - - Major Facilitator Superfamily
IMBHKMNO_03454 8.37e-273 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMBHKMNO_03456 4.28e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IMBHKMNO_03457 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IMBHKMNO_03458 7.12e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IMBHKMNO_03459 4.56e-312 steT - - E ko:K03294 - ko00000 amino acid
IMBHKMNO_03460 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IMBHKMNO_03461 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
IMBHKMNO_03462 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IMBHKMNO_03463 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IMBHKMNO_03464 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IMBHKMNO_03465 2.72e-51 xhlB - - S - - - SPP1 phage holin
IMBHKMNO_03466 3.87e-51 xhlA - - S - - - Haemolysin XhlA
IMBHKMNO_03467 1.05e-176 xepA - - - - - - -
IMBHKMNO_03468 3.25e-40 xkdX - - - - - - -
IMBHKMNO_03470 4.99e-39 - - - - - - - -
IMBHKMNO_03471 1.39e-53 xkdQ - - G - - - NLP P60 protein
IMBHKMNO_03472 3.05e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IMBHKMNO_03476 8.78e-196 xkdC - - L - - - Bacterial dnaA protein
IMBHKMNO_03478 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
IMBHKMNO_03479 3.1e-143 xkdA - - E - - - IrrE N-terminal-like domain
IMBHKMNO_03480 1.85e-142 yjqB - - S - - - phage-related replication protein
IMBHKMNO_03481 9.51e-81 yjqA - - S - - - Bacterial PH domain
IMBHKMNO_03482 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IMBHKMNO_03484 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IMBHKMNO_03485 8.38e-103 yjoA - - S - - - DinB family
IMBHKMNO_03486 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IMBHKMNO_03487 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IMBHKMNO_03488 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IMBHKMNO_03489 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IMBHKMNO_03490 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
IMBHKMNO_03491 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IMBHKMNO_03492 6.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IMBHKMNO_03493 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IMBHKMNO_03494 2.87e-117 yjlB - - S - - - Cupin domain
IMBHKMNO_03495 6.82e-226 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IMBHKMNO_03496 6.49e-168 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03497 3.78e-137 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IMBHKMNO_03498 2.27e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IMBHKMNO_03499 1.73e-40 - - - - - - - -
IMBHKMNO_03500 1.64e-283 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IMBHKMNO_03501 2.45e-286 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IMBHKMNO_03502 1.81e-116 yjgD - - S - - - Protein of unknown function (DUF1641)
IMBHKMNO_03503 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IMBHKMNO_03504 2.76e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
IMBHKMNO_03505 8.23e-88 yjgA - - T - - - Protein of unknown function (DUF2809)
IMBHKMNO_03506 3.18e-30 yjfB - - S - - - Putative motility protein
IMBHKMNO_03508 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IMBHKMNO_03509 6.88e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_03510 6.86e-46 - - - - - - - -
IMBHKMNO_03511 1.45e-161 - - - S - - - Haloacid dehalogenase-like hydrolase
IMBHKMNO_03512 2.4e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IMBHKMNO_03513 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMBHKMNO_03514 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_03515 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMBHKMNO_03516 7.4e-275 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMBHKMNO_03517 4.52e-237 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IMBHKMNO_03518 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IMBHKMNO_03519 5.67e-283 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IMBHKMNO_03520 6.11e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_03521 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
IMBHKMNO_03522 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IMBHKMNO_03523 5.33e-212 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IMBHKMNO_03524 1.1e-76 - - - E - - - Glyoxalase-like domain
IMBHKMNO_03527 1.33e-95 - - - E - - - phosphoribosylanthranilate isomerase activity
IMBHKMNO_03528 3.16e-65 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
IMBHKMNO_03529 6.4e-106 - - - S - - - Alpha beta hydrolase
IMBHKMNO_03531 2.78e-315 - - - S - - - Bacterial EndoU nuclease
IMBHKMNO_03532 1.14e-41 - - - - - - - -
IMBHKMNO_03533 0.0 - - - V - - - COG1002 Type II restriction enzyme, methylase subunits
IMBHKMNO_03539 1.65e-12 - - - K - - - Helix-turn-helix XRE-family like proteins
IMBHKMNO_03541 1.58e-20 - - - K - - - Helix-turn-helix domain
IMBHKMNO_03543 1.09e-34 - - - M - - - D-alanyl-D-alanine carboxypeptidase
IMBHKMNO_03545 4.74e-43 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IMBHKMNO_03546 1.41e-26 - - - S - - - Phage head-tail joining protein
IMBHKMNO_03548 9.53e-132 - - - S - - - capsid protein
IMBHKMNO_03549 2.8e-68 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
IMBHKMNO_03550 6.79e-183 - - - S - - - portal protein
IMBHKMNO_03552 9.42e-163 terL - - S - - - Terminase
IMBHKMNO_03553 4.47e-68 - - - L - - - Terminase, small subunit
IMBHKMNO_03562 6.77e-67 - - - K - - - BRO family, N-terminal domain
IMBHKMNO_03563 3.62e-243 - - - - - - - -
IMBHKMNO_03569 2.65e-77 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
IMBHKMNO_03572 2.93e-100 - - - L - - - Belongs to the 'phage' integrase family
IMBHKMNO_03574 8.08e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IMBHKMNO_03575 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IMBHKMNO_03576 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IMBHKMNO_03577 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IMBHKMNO_03578 7.11e-96 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMBHKMNO_03579 4.32e-48 - - - K - - - SpoVT / AbrB like domain
IMBHKMNO_03580 3.95e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IMBHKMNO_03581 1.31e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IMBHKMNO_03582 4.16e-181 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IMBHKMNO_03583 4.12e-47 - - - - - - - -
IMBHKMNO_03584 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IMBHKMNO_03585 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
IMBHKMNO_03586 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IMBHKMNO_03589 2.92e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
IMBHKMNO_03590 9.7e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IMBHKMNO_03591 1.02e-36 cotW - - - ko:K06341 - ko00000 -
IMBHKMNO_03592 2.14e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IMBHKMNO_03593 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IMBHKMNO_03594 1.12e-103 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IMBHKMNO_03595 2.9e-126 yjbX - - S - - - Spore coat protein
IMBHKMNO_03596 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IMBHKMNO_03597 1.83e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IMBHKMNO_03598 7.85e-241 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IMBHKMNO_03599 7.36e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IMBHKMNO_03600 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
IMBHKMNO_03601 2.26e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IMBHKMNO_03602 7.77e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IMBHKMNO_03603 3.3e-176 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMBHKMNO_03604 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IMBHKMNO_03605 1.84e-184 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IMBHKMNO_03606 9.09e-10 - - - L - - - COG2963 Transposase and inactivated derivatives
IMBHKMNO_03607 1.09e-48 - - - L - - - COG2963 Transposase and inactivated derivatives
IMBHKMNO_03608 1.11e-174 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
IMBHKMNO_03609 2.35e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IMBHKMNO_03610 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMBHKMNO_03611 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IMBHKMNO_03612 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
IMBHKMNO_03613 4.23e-129 yjbK - - S - - - protein conserved in bacteria
IMBHKMNO_03614 2.56e-151 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IMBHKMNO_03615 5.81e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IMBHKMNO_03616 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IMBHKMNO_03617 3.14e-27 - - - - - - - -
IMBHKMNO_03618 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IMBHKMNO_03619 2.04e-275 coiA - - S ko:K06198 - ko00000 Competence protein
IMBHKMNO_03620 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IMBHKMNO_03621 4.79e-142 yjbE - - P - - - Integral membrane protein TerC family
IMBHKMNO_03622 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IMBHKMNO_03623 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMBHKMNO_03624 5.81e-294 - - - S - - - Putative glycosyl hydrolase domain
IMBHKMNO_03625 1.42e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03626 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03627 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03628 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03629 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IMBHKMNO_03630 2.92e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IMBHKMNO_03631 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
IMBHKMNO_03632 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03633 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03634 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IMBHKMNO_03635 2.94e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03636 4.15e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03637 8.73e-189 yjaZ - - O - - - Zn-dependent protease
IMBHKMNO_03638 1.29e-298 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMBHKMNO_03639 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMBHKMNO_03640 2.82e-44 yjzB - - - - - - -
IMBHKMNO_03641 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IMBHKMNO_03642 6.64e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IMBHKMNO_03643 1.67e-134 yjaV - - - - - - -
IMBHKMNO_03644 4.68e-180 yjaU - - I - - - carboxylic ester hydrolase activity
IMBHKMNO_03645 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
IMBHKMNO_03646 7.21e-39 yjzC - - S - - - YjzC-like protein
IMBHKMNO_03647 3.52e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMBHKMNO_03648 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IMBHKMNO_03649 6.9e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IMBHKMNO_03650 2.68e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IMBHKMNO_03651 7.35e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IMBHKMNO_03652 1.09e-291 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMBHKMNO_03653 1.95e-250 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMBHKMNO_03654 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
IMBHKMNO_03655 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IMBHKMNO_03656 2.36e-105 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IMBHKMNO_03657 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IMBHKMNO_03658 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IMBHKMNO_03659 5.93e-196 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IMBHKMNO_03660 1.49e-11 - - - - - - - -
IMBHKMNO_03661 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
IMBHKMNO_03662 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
IMBHKMNO_03663 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IMBHKMNO_03664 9.13e-202 yitS - - S - - - protein conserved in bacteria
IMBHKMNO_03665 7.56e-08 - - - S - - - Domain of unknown function (DUF3941)
IMBHKMNO_03666 3.61e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IMBHKMNO_03667 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IMBHKMNO_03668 6.25e-221 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
IMBHKMNO_03669 4.55e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IMBHKMNO_03670 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IMBHKMNO_03671 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IMBHKMNO_03672 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
IMBHKMNO_03673 2.93e-99 yisX - - S - - - Pentapeptide repeats (9 copies)
IMBHKMNO_03674 2.27e-109 yisT - - S - - - DinB family
IMBHKMNO_03675 5.97e-198 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IMBHKMNO_03676 5.83e-183 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IMBHKMNO_03677 1.16e-206 yisR - - K - - - Transcriptional regulator
IMBHKMNO_03678 2.25e-312 yisQ - - V - - - Mate efflux family protein
IMBHKMNO_03679 1e-166 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IMBHKMNO_03680 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IMBHKMNO_03681 1.78e-122 yisN - - S - - - Protein of unknown function (DUF2777)
IMBHKMNO_03682 6.36e-78 yisL - - S - - - UPF0344 protein
IMBHKMNO_03683 8.91e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IMBHKMNO_03684 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
IMBHKMNO_03685 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IMBHKMNO_03686 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
IMBHKMNO_03687 9.91e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IMBHKMNO_03688 5e-32 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IMBHKMNO_03689 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IMBHKMNO_03690 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IMBHKMNO_03691 7.31e-65 yisB - - V - - - COG1403 Restriction endonuclease
IMBHKMNO_03692 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IMBHKMNO_03693 8.13e-284 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IMBHKMNO_03694 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IMBHKMNO_03695 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IMBHKMNO_03696 2.88e-159 ydfS - - S - - - Protein of unknown function (DUF421)
IMBHKMNO_03697 1.79e-122 yhjR - - S - - - Rubrerythrin
IMBHKMNO_03698 3.71e-140 - - - K - - - QacR-like protein, C-terminal region
IMBHKMNO_03699 2.64e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_03700 2.82e-261 yhjN - - S ko:K07120 - ko00000 membrane
IMBHKMNO_03701 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_03702 0.0 yhjG - - CH - - - FAD binding domain
IMBHKMNO_03703 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IMBHKMNO_03704 2.23e-142 yhjE - - S - - - SNARE associated Golgi protein
IMBHKMNO_03705 4.12e-79 yhjD - - - - - - -
IMBHKMNO_03706 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
IMBHKMNO_03707 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMBHKMNO_03708 2.64e-63 - - - S - - - Belongs to the UPF0145 family
IMBHKMNO_03709 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
IMBHKMNO_03710 1.14e-165 yrpD - - S - - - Domain of unknown function, YrpD
IMBHKMNO_03711 4.72e-209 - - - S - - - Acetyltransferase, GNAT family
IMBHKMNO_03712 2.64e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IMBHKMNO_03713 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IMBHKMNO_03714 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IMBHKMNO_03715 9.48e-43 yhzC - - S - - - IDEAL
IMBHKMNO_03716 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_03717 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IMBHKMNO_03718 4.6e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IMBHKMNO_03719 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IMBHKMNO_03720 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IMBHKMNO_03721 2.48e-253 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IMBHKMNO_03722 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IMBHKMNO_03723 1.27e-192 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IMBHKMNO_03724 2.23e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IMBHKMNO_03725 1.24e-298 yhfN - - O - - - Peptidase M48
IMBHKMNO_03726 6.81e-86 yhfM - - - - - - -
IMBHKMNO_03727 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IMBHKMNO_03728 2.58e-142 yhfK - - GM - - - NmrA-like family
IMBHKMNO_03729 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IMBHKMNO_03730 4.68e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IMBHKMNO_03732 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IMBHKMNO_03733 5.41e-253 yhfE - - G - - - peptidase M42
IMBHKMNO_03735 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMBHKMNO_03736 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IMBHKMNO_03737 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03738 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IMBHKMNO_03739 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IMBHKMNO_03740 7.35e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IMBHKMNO_03741 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMBHKMNO_03742 2.18e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IMBHKMNO_03743 3.27e-310 yhfA - - C - - - membrane
IMBHKMNO_03744 1.03e-284 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IMBHKMNO_03745 5e-161 ecsC - - S - - - EcsC protein family
IMBHKMNO_03746 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IMBHKMNO_03747 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IMBHKMNO_03748 1.67e-104 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IMBHKMNO_03749 1.69e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMBHKMNO_03750 4.77e-99 trpP - - S - - - Tryptophan transporter TrpP
IMBHKMNO_03751 4.4e-25 - - - - - - - -
IMBHKMNO_03752 2.74e-54 yhaH - - S - - - YtxH-like protein
IMBHKMNO_03753 3.33e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IMBHKMNO_03754 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
IMBHKMNO_03755 1.29e-123 yhaK - - S - - - Putative zincin peptidase
IMBHKMNO_03756 1.26e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IMBHKMNO_03757 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
IMBHKMNO_03758 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IMBHKMNO_03759 0.0 yhaN - - L - - - AAA domain
IMBHKMNO_03760 3.86e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IMBHKMNO_03761 2.79e-276 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IMBHKMNO_03762 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_03763 1.65e-18 - - - S - - - YhzD-like protein
IMBHKMNO_03764 1.18e-174 yhaR - - I - - - enoyl-CoA hydratase
IMBHKMNO_03766 4.58e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IMBHKMNO_03767 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IMBHKMNO_03768 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
IMBHKMNO_03769 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IMBHKMNO_03770 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IMBHKMNO_03771 3.37e-256 yhaZ - - L - - - DNA alkylation repair enzyme
IMBHKMNO_03772 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
IMBHKMNO_03773 1.3e-262 yheB - - S - - - Belongs to the UPF0754 family
IMBHKMNO_03774 7.63e-273 yheC - - HJ - - - YheC/D like ATP-grasp
IMBHKMNO_03775 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IMBHKMNO_03776 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
IMBHKMNO_03777 6.66e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IMBHKMNO_03779 3.86e-142 yheG - - GM - - - NAD(P)H-binding
IMBHKMNO_03780 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IMBHKMNO_03781 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IMBHKMNO_03783 2.49e-110 - - - T - - - universal stress protein
IMBHKMNO_03784 1.55e-123 ymcC - - S - - - Membrane
IMBHKMNO_03785 1.43e-113 pksA - - K - - - Transcriptional regulator
IMBHKMNO_03786 8.4e-198 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IMBHKMNO_03787 6.94e-201 nodB1 - - G - - - deacetylase
IMBHKMNO_03788 4.85e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IMBHKMNO_03789 1.57e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IMBHKMNO_03790 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
IMBHKMNO_03791 1.49e-164 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IMBHKMNO_03792 5.18e-81 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMBHKMNO_03793 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMBHKMNO_03794 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IMBHKMNO_03795 1.57e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMBHKMNO_03796 2.34e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IMBHKMNO_03797 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IMBHKMNO_03798 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IMBHKMNO_03799 1.86e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IMBHKMNO_03800 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_03801 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IMBHKMNO_03802 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
IMBHKMNO_03803 7.22e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IMBHKMNO_03804 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
IMBHKMNO_03805 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_03806 3.86e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IMBHKMNO_03807 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03808 2.93e-173 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IMBHKMNO_03809 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IMBHKMNO_03810 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IMBHKMNO_03811 0.0 ygxB - - M - - - Conserved TM helix
IMBHKMNO_03812 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IMBHKMNO_03813 1.16e-294 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IMBHKMNO_03814 6.94e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
IMBHKMNO_03815 6.98e-53 yhdB - - S - - - YhdB-like protein
IMBHKMNO_03816 5.65e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IMBHKMNO_03817 3.15e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMBHKMNO_03818 6.16e-262 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IMBHKMNO_03819 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IMBHKMNO_03820 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMBHKMNO_03821 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMBHKMNO_03822 1.91e-197 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IMBHKMNO_03823 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IMBHKMNO_03824 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMBHKMNO_03825 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IMBHKMNO_03826 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
IMBHKMNO_03827 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
IMBHKMNO_03828 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
IMBHKMNO_03829 9.64e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IMBHKMNO_03830 2.25e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IMBHKMNO_03831 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMBHKMNO_03832 4.45e-151 yhcQ - - M - - - Spore coat protein
IMBHKMNO_03833 3.33e-207 yhcP - - - - - - -
IMBHKMNO_03834 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IMBHKMNO_03835 5.32e-75 yhcM - - - - - - -
IMBHKMNO_03836 7.04e-306 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IMBHKMNO_03837 3.02e-236 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IMBHKMNO_03838 2.39e-189 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IMBHKMNO_03839 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IMBHKMNO_03840 4.49e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IMBHKMNO_03841 2.35e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_03842 1.78e-162 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMBHKMNO_03843 9.51e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03844 9.36e-66 - - - - - - - -
IMBHKMNO_03845 4.73e-71 yhcC - - - - - - -
IMBHKMNO_03846 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IMBHKMNO_03847 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IMBHKMNO_03848 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IMBHKMNO_03849 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IMBHKMNO_03850 1.13e-275 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IMBHKMNO_03851 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IMBHKMNO_03852 1.23e-07 - - - - - - - -
IMBHKMNO_03853 5.77e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IMBHKMNO_03854 1.4e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IMBHKMNO_03855 2.3e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
IMBHKMNO_03856 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IMBHKMNO_03857 2.04e-224 yhbB - - S - - - Putative amidase domain
IMBHKMNO_03858 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMBHKMNO_03859 3.06e-144 yhzB - - S - - - B3/4 domain
IMBHKMNO_03861 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IMBHKMNO_03862 1.06e-105 ygaO - - - - - - -
IMBHKMNO_03863 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMBHKMNO_03865 2.03e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IMBHKMNO_03866 9.64e-185 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IMBHKMNO_03867 1.75e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IMBHKMNO_03868 1.29e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IMBHKMNO_03869 6.12e-230 - - - S ko:K07045 - ko00000 Amidohydrolase
IMBHKMNO_03870 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IMBHKMNO_03871 1.41e-169 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03872 1.9e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMBHKMNO_03873 1.77e-161 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMBHKMNO_03874 8.22e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMBHKMNO_03875 6.68e-293 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
IMBHKMNO_03877 0.0 ygaK - - C - - - Berberine and berberine like
IMBHKMNO_03878 8.8e-95 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IMBHKMNO_03879 2.19e-257 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IMBHKMNO_03880 1.24e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IMBHKMNO_03881 0.0 - - - C - - - Na+/H+ antiporter family
IMBHKMNO_03890 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IMBHKMNO_03891 1.08e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IMBHKMNO_03892 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
IMBHKMNO_03893 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
IMBHKMNO_03894 5.73e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IMBHKMNO_03895 1.09e-53 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IMBHKMNO_03896 1.46e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IMBHKMNO_03897 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IMBHKMNO_03898 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IMBHKMNO_03899 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IMBHKMNO_03900 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IMBHKMNO_03901 9.89e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IMBHKMNO_03902 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IMBHKMNO_03903 2.23e-166 yfmS - - NT - - - chemotaxis protein
IMBHKMNO_03904 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IMBHKMNO_03905 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
IMBHKMNO_03906 3.84e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_03907 1.99e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IMBHKMNO_03908 1.78e-285 yfnE - - S - - - Glycosyltransferase like family 2
IMBHKMNO_03909 2.21e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IMBHKMNO_03910 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IMBHKMNO_03911 3.57e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IMBHKMNO_03912 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IMBHKMNO_03913 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IMBHKMNO_03914 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
IMBHKMNO_03915 1.65e-262 yetM - - CH - - - FAD binding domain
IMBHKMNO_03916 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IMBHKMNO_03917 1.54e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IMBHKMNO_03918 1.06e-72 - - - H - - - riboflavin kinase activity
IMBHKMNO_03919 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
IMBHKMNO_03920 1.69e-166 cysA 3.6.3.25 - P ko:K02045 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IMBHKMNO_03921 5.95e-135 cysW - - P ko:K02047 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG4208 ABC-type sulfate transport system, permease component
IMBHKMNO_03922 2.39e-142 cysT - - O ko:K02046 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0555 ABC-type sulfate transport system, permease component
IMBHKMNO_03923 3.08e-176 sbp - - P ko:K02048 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG1613 ABC-type sulfate transport system, periplasmic component
IMBHKMNO_03924 1.8e-196 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IMBHKMNO_03925 3.11e-84 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IMBHKMNO_03926 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IMBHKMNO_03927 3.01e-155 yetF - - S - - - membrane
IMBHKMNO_03928 5.92e-05 - - - - - - - -
IMBHKMNO_03929 4.48e-120 yesJ - - K - - - Acetyltransferase (GNAT) family
IMBHKMNO_03930 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IMBHKMNO_03931 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IMBHKMNO_03932 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IMBHKMNO_03933 4.94e-137 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IMBHKMNO_03935 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
IMBHKMNO_03936 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
IMBHKMNO_03937 4.08e-107 - - - S - - - Protein of unknown function, DUF600
IMBHKMNO_03939 6.66e-39 - - - S - - - Colicin immunity protein / pyocin immunity protein
IMBHKMNO_03941 1.39e-85 - - - - - - - -
IMBHKMNO_03942 1.68e-140 - - - L - - - AAA domain
IMBHKMNO_03943 3.34e-249 - - - L - - - AAA ATPase domain
IMBHKMNO_03944 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMBHKMNO_03945 4.95e-216 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IMBHKMNO_03946 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMBHKMNO_03947 1.83e-196 yerO - - K - - - Transcriptional regulator
IMBHKMNO_03948 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMBHKMNO_03949 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IMBHKMNO_03950 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMBHKMNO_03951 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMBHKMNO_03952 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IMBHKMNO_03953 8.91e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IMBHKMNO_03954 4.55e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IMBHKMNO_03955 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMBHKMNO_03956 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IMBHKMNO_03957 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IMBHKMNO_03958 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IMBHKMNO_03959 2.03e-67 yerC - - S - - - protein conserved in bacteria
IMBHKMNO_03960 2.98e-247 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IMBHKMNO_03961 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IMBHKMNO_03962 1.7e-33 - - - S - - - Protein of unknown function (DUF2892)
IMBHKMNO_03963 6.93e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IMBHKMNO_03964 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IMBHKMNO_03965 4.93e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMBHKMNO_03966 1.26e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IMBHKMNO_03967 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMBHKMNO_03968 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMBHKMNO_03969 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMBHKMNO_03970 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMBHKMNO_03971 4.13e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IMBHKMNO_03972 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMBHKMNO_03973 5.32e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMBHKMNO_03974 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMBHKMNO_03975 6.56e-40 yebG - - S - - - NETI protein
IMBHKMNO_03976 2.98e-119 yebE - - S - - - UPF0316 protein
IMBHKMNO_03978 8.8e-168 yebC - - M - - - Membrane
IMBHKMNO_03979 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IMBHKMNO_03980 1.56e-315 - - - S - - - Domain of unknown function (DUF4179)
IMBHKMNO_03981 2.31e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_03982 1.92e-164 - - - K - - - Acetyltransferase (GNAT) domain
IMBHKMNO_03983 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IMBHKMNO_03984 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IMBHKMNO_03985 1.62e-276 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IMBHKMNO_03986 6.84e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IMBHKMNO_03987 3.54e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMBHKMNO_03988 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IMBHKMNO_03989 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IMBHKMNO_03990 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
IMBHKMNO_03992 2.12e-196 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IMBHKMNO_03993 1.6e-82 ydjM - - M - - - Lytic transglycolase
IMBHKMNO_03994 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IMBHKMNO_03995 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IMBHKMNO_03996 4.82e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
IMBHKMNO_03997 0.0 oatA - - I - - - Acyltransferase family
IMBHKMNO_03998 1.31e-222 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IMBHKMNO_03999 2.24e-162 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IMBHKMNO_04000 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMBHKMNO_04001 2.75e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IMBHKMNO_04002 1.79e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
IMBHKMNO_04003 4.07e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IMBHKMNO_04004 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IMBHKMNO_04005 4.14e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IMBHKMNO_04006 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IMBHKMNO_04008 4.72e-150 - - - - - - - -
IMBHKMNO_04010 7.39e-106 - - - KL - - - HELICc2
IMBHKMNO_04011 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IMBHKMNO_04012 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMBHKMNO_04013 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IMBHKMNO_04014 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IMBHKMNO_04015 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMBHKMNO_04016 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IMBHKMNO_04017 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMBHKMNO_04018 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IMBHKMNO_04019 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IMBHKMNO_04020 9.22e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMBHKMNO_04021 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IMBHKMNO_04022 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IMBHKMNO_04023 5.22e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IMBHKMNO_04024 2.41e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IMBHKMNO_04026 7.89e-213 ygxA - - S - - - Nucleotidyltransferase-like
IMBHKMNO_04027 6.64e-75 ygzB - - S - - - UPF0295 protein
IMBHKMNO_04028 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IMBHKMNO_04029 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IMBHKMNO_04030 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IMBHKMNO_04031 9.11e-240 ygaE - - S - - - Membrane
IMBHKMNO_04032 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IMBHKMNO_04033 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IMBHKMNO_04034 1.4e-49 ygaB - - S - - - YgaB-like protein
IMBHKMNO_04035 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IMBHKMNO_04036 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IMBHKMNO_04037 1.04e-49 yfhS - - - - - - -
IMBHKMNO_04038 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IMBHKMNO_04039 1.98e-234 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IMBHKMNO_04040 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IMBHKMNO_04041 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IMBHKMNO_04042 6.53e-217 - - - S - - - Alpha/beta hydrolase family
IMBHKMNO_04043 1.73e-56 yfhL - - S - - - SdpI/YhfL protein family
IMBHKMNO_04044 8.09e-122 yfhK - - T - - - Bacterial SH3 domain homologues
IMBHKMNO_04045 2.57e-59 yfhJ - - S - - - WVELL protein
IMBHKMNO_04046 2.45e-216 mpr - - M - - - Belongs to the peptidase S1B family
IMBHKMNO_04048 4.06e-268 yfhI - - EGP - - - -transporter
IMBHKMNO_04049 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IMBHKMNO_04050 5.21e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IMBHKMNO_04051 1.04e-215 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IMBHKMNO_04053 3.61e-34 yfhD - - S - - - YfhD-like protein
IMBHKMNO_04054 3.35e-137 yfhC - - C - - - nitroreductase
IMBHKMNO_04055 7.26e-209 yfhB - - S - - - PhzF family
IMBHKMNO_04056 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMBHKMNO_04057 1.38e-108 yfiV - - K - - - transcriptional
IMBHKMNO_04058 0.0 yfiU - - EGP - - - the major facilitator superfamily
IMBHKMNO_04059 1.34e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IMBHKMNO_04060 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IMBHKMNO_04061 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IMBHKMNO_04062 1.09e-235 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IMBHKMNO_04063 2.97e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IMBHKMNO_04064 1.61e-125 padR - - K - - - transcriptional
IMBHKMNO_04065 1.6e-218 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IMBHKMNO_04066 4.79e-243 - - - S - - - Oxidoreductase
IMBHKMNO_04067 5.49e-98 - - - G - - - Xylose isomerase
IMBHKMNO_04068 5e-87 - - - G - - - Xylose isomerase
IMBHKMNO_04069 1.26e-240 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IMBHKMNO_04070 2.91e-125 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
IMBHKMNO_04071 5.74e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IMBHKMNO_04072 5.54e-82 yfiD3 - - S - - - DoxX
IMBHKMNO_04073 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IMBHKMNO_04074 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IMBHKMNO_04075 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_04076 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IMBHKMNO_04077 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IMBHKMNO_04078 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IMBHKMNO_04079 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IMBHKMNO_04080 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IMBHKMNO_04081 3.39e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMBHKMNO_04082 5.32e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IMBHKMNO_04083 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IMBHKMNO_04084 1.42e-122 yfjM - - S - - - Psort location Cytoplasmic, score
IMBHKMNO_04085 4.93e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMBHKMNO_04086 4.65e-47 - - - S - - - YfzA-like protein
IMBHKMNO_04087 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMBHKMNO_04088 2.85e-207 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IMBHKMNO_04089 2.5e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IMBHKMNO_04091 2.19e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IMBHKMNO_04092 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IMBHKMNO_04093 7.99e-37 yfjT - - - - - - -
IMBHKMNO_04094 2.4e-281 yfkA - - S - - - YfkB-like domain
IMBHKMNO_04095 3.01e-188 yfkC - - M - - - Mechanosensitive ion channel
IMBHKMNO_04096 9.38e-185 yfkD - - S - - - YfkD-like protein
IMBHKMNO_04097 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IMBHKMNO_04098 8.37e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_04099 1.37e-12 - - - - - - - -
IMBHKMNO_04100 7.92e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IMBHKMNO_04101 8.74e-69 yfkI - - S - - - gas vesicle protein
IMBHKMNO_04102 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMBHKMNO_04103 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
IMBHKMNO_04104 5.73e-251 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IMBHKMNO_04105 6.81e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IMBHKMNO_04106 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMBHKMNO_04107 7.5e-238 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IMBHKMNO_04108 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IMBHKMNO_04109 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IMBHKMNO_04110 1.19e-245 yibE - - S - - - YibE/F-like protein
IMBHKMNO_04111 2.44e-166 yibF - - S - - - YibE/F-like protein
IMBHKMNO_04112 1.45e-158 frp - - C - - - nitroreductase
IMBHKMNO_04113 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IMBHKMNO_04114 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IMBHKMNO_04115 3.86e-314 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMBHKMNO_04116 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
IMBHKMNO_04117 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
IMBHKMNO_04118 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IMBHKMNO_04119 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IMBHKMNO_04120 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IMBHKMNO_04121 2.35e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IMBHKMNO_04122 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IMBHKMNO_04123 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IMBHKMNO_04124 1.96e-65 yflH - - S - - - Protein of unknown function (DUF3243)
IMBHKMNO_04125 1.98e-26 yflI - - - - - - -
IMBHKMNO_04126 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
IMBHKMNO_04127 3.57e-158 yflK - - S - - - protein conserved in bacteria
IMBHKMNO_04128 5.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IMBHKMNO_04129 1.23e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IMBHKMNO_04130 4.87e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IMBHKMNO_04131 5.77e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IMBHKMNO_04132 5.61e-224 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IMBHKMNO_04133 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IMBHKMNO_04134 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IMBHKMNO_04135 7.87e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IMBHKMNO_04136 0.0 - - - M - - - cell wall anchor domain
IMBHKMNO_04137 5.87e-182 - - - M - - - cell wall anchor domain
IMBHKMNO_04138 6.79e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
IMBHKMNO_04139 0.0 ywpD - - T - - - Histidine kinase
IMBHKMNO_04140 2.98e-93 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
IMBHKMNO_04141 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IMBHKMNO_04142 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IMBHKMNO_04143 6.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IMBHKMNO_04144 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IMBHKMNO_04145 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMBHKMNO_04146 8.93e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IMBHKMNO_04147 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IMBHKMNO_04148 5.61e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IMBHKMNO_04149 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IMBHKMNO_04150 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMBHKMNO_04151 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IMBHKMNO_04152 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IMBHKMNO_04153 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMBHKMNO_04154 2.9e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMBHKMNO_04155 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IMBHKMNO_04156 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IMBHKMNO_04157 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IMBHKMNO_04158 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IMBHKMNO_04159 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMBHKMNO_04160 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IMBHKMNO_04161 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMBHKMNO_04162 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IMBHKMNO_04163 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IMBHKMNO_04164 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMBHKMNO_04165 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMBHKMNO_04166 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IMBHKMNO_04167 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMBHKMNO_04168 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IMBHKMNO_04169 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMBHKMNO_04170 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMBHKMNO_04171 1.41e-240 ybaC - - S - - - Alpha/beta hydrolase family
IMBHKMNO_04172 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IMBHKMNO_04173 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMBHKMNO_04174 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IMBHKMNO_04175 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IMBHKMNO_04176 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMBHKMNO_04177 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMBHKMNO_04178 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMBHKMNO_04179 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMBHKMNO_04180 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMBHKMNO_04181 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IMBHKMNO_04182 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMBHKMNO_04183 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMBHKMNO_04184 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMBHKMNO_04185 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMBHKMNO_04186 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMBHKMNO_04187 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMBHKMNO_04188 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMBHKMNO_04189 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMBHKMNO_04190 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMBHKMNO_04191 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IMBHKMNO_04192 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IMBHKMNO_04193 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IMBHKMNO_04194 3.57e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IMBHKMNO_04195 1.34e-181 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IMBHKMNO_04196 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMBHKMNO_04197 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IMBHKMNO_04198 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMBHKMNO_04199 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMBHKMNO_04200 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMBHKMNO_04201 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IMBHKMNO_04202 2.51e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMBHKMNO_04203 8.49e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMBHKMNO_04204 6.51e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMBHKMNO_04205 1.02e-180 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IMBHKMNO_04206 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMBHKMNO_04207 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IMBHKMNO_04208 4.15e-184 ybaJ - - Q - - - Methyltransferase domain
IMBHKMNO_04209 9.03e-108 yizA - - S - - - Damage-inducible protein DinB
IMBHKMNO_04210 3.22e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
IMBHKMNO_04211 1.15e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IMBHKMNO_04212 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IMBHKMNO_04213 3.93e-102 gerD - - - ko:K06294 - ko00000 -
IMBHKMNO_04214 5.1e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IMBHKMNO_04215 2.6e-182 pdaB - - G - - - Polysaccharide deacetylase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)