ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NNGKNKDC_00001 4.72e-71 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NNGKNKDC_00002 5.51e-205 yisR - - K - - - Transcriptional regulator
NNGKNKDC_00003 6.44e-312 yisQ - - V - - - Mate efflux family protein
NNGKNKDC_00004 4.45e-170 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NNGKNKDC_00005 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNGKNKDC_00006 1.07e-123 yisN - - S - - - Protein of unknown function (DUF2777)
NNGKNKDC_00007 2.22e-78 yisL - - S - - - UPF0344 protein
NNGKNKDC_00008 8.91e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NNGKNKDC_00009 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
NNGKNKDC_00010 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NNGKNKDC_00011 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
NNGKNKDC_00012 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NNGKNKDC_00013 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NNGKNKDC_00014 1.88e-83 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NNGKNKDC_00015 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NNGKNKDC_00016 1.53e-66 yisB - - V - - - COG1403 Restriction endonuclease
NNGKNKDC_00017 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NNGKNKDC_00018 9.49e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNGKNKDC_00019 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NNGKNKDC_00020 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NNGKNKDC_00021 7.06e-160 ydfS - - S - - - Protein of unknown function (DUF421)
NNGKNKDC_00022 1.79e-122 yhjR - - S - - - Rubrerythrin
NNGKNKDC_00023 3.7e-138 - - - K - - - QacR-like protein, C-terminal region
NNGKNKDC_00024 5.11e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_00025 4.88e-262 yhjN - - S ko:K07120 - ko00000 membrane
NNGKNKDC_00026 9.87e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_00027 0.0 yhjG - - CH - - - FAD binding domain
NNGKNKDC_00029 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNGKNKDC_00030 1.57e-142 yhjE - - S - - - SNARE associated Golgi protein
NNGKNKDC_00031 2.04e-79 yhjD - - - - - - -
NNGKNKDC_00032 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
NNGKNKDC_00033 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNGKNKDC_00034 2.64e-63 - - - S - - - Belongs to the UPF0145 family
NNGKNKDC_00035 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
NNGKNKDC_00036 2.88e-161 yrpD - - S - - - Domain of unknown function, YrpD
NNGKNKDC_00037 3.5e-211 - - - S - - - Acetyltransferase, GNAT family
NNGKNKDC_00038 3.46e-120 - - - S - - - MepB protein
NNGKNKDC_00039 3.75e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NNGKNKDC_00040 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NNGKNKDC_00041 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NNGKNKDC_00042 9.48e-43 yhzC - - S - - - IDEAL
NNGKNKDC_00043 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_00044 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NNGKNKDC_00045 9.28e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NNGKNKDC_00046 1.78e-114 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NNGKNKDC_00047 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NNGKNKDC_00048 1.01e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NNGKNKDC_00049 7.04e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NNGKNKDC_00050 1.61e-195 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NNGKNKDC_00051 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNGKNKDC_00052 6.42e-301 yhfN - - O - - - Peptidase M48
NNGKNKDC_00053 6.81e-86 yhfM - - - - - - -
NNGKNKDC_00054 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NNGKNKDC_00055 4.45e-143 yhfK - - GM - - - NmrA-like family
NNGKNKDC_00056 3.74e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NNGKNKDC_00057 6.65e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NNGKNKDC_00058 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNGKNKDC_00059 5.19e-251 yhfE - - G - - - peptidase M42
NNGKNKDC_00061 2.41e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNGKNKDC_00062 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NNGKNKDC_00063 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00064 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NNGKNKDC_00065 7.76e-233 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NNGKNKDC_00066 7.35e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NNGKNKDC_00067 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNGKNKDC_00068 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NNGKNKDC_00069 5.65e-311 yhfA - - C - - - membrane
NNGKNKDC_00070 4.38e-286 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NNGKNKDC_00071 2.04e-160 ecsC - - S - - - EcsC protein family
NNGKNKDC_00072 3.18e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNGKNKDC_00073 1.75e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NNGKNKDC_00074 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NNGKNKDC_00075 6.9e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNGKNKDC_00076 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
NNGKNKDC_00077 2.55e-24 - - - - - - - -
NNGKNKDC_00078 1.93e-54 yhaH - - S - - - YtxH-like protein
NNGKNKDC_00079 4.73e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NNGKNKDC_00080 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NNGKNKDC_00081 1.29e-123 yhaK - - S - - - Putative zincin peptidase
NNGKNKDC_00082 1.36e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNGKNKDC_00083 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
NNGKNKDC_00084 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NNGKNKDC_00085 0.0 yhaN - - L - - - AAA domain
NNGKNKDC_00086 1.83e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NNGKNKDC_00087 4.82e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NNGKNKDC_00088 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00089 5.99e-21 - - - S - - - YhzD-like protein
NNGKNKDC_00090 1.18e-174 yhaR - - I - - - enoyl-CoA hydratase
NNGKNKDC_00092 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NNGKNKDC_00093 1.64e-265 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NNGKNKDC_00094 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
NNGKNKDC_00095 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NNGKNKDC_00096 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NNGKNKDC_00097 7.1e-258 yhaZ - - L - - - DNA alkylation repair enzyme
NNGKNKDC_00098 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
NNGKNKDC_00099 3.19e-263 yheB - - S - - - Belongs to the UPF0754 family
NNGKNKDC_00100 1.08e-272 yheC - - HJ - - - YheC/D like ATP-grasp
NNGKNKDC_00101 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NNGKNKDC_00102 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
NNGKNKDC_00103 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NNGKNKDC_00105 1.35e-142 yheG - - GM - - - NAD(P)H-binding
NNGKNKDC_00106 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNGKNKDC_00107 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNGKNKDC_00109 1.18e-108 - - - T - - - universal stress protein
NNGKNKDC_00110 1.55e-123 ymcC - - S - - - Membrane
NNGKNKDC_00111 1.22e-114 pksA - - K - - - Transcriptional regulator
NNGKNKDC_00112 9.8e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NNGKNKDC_00113 1.99e-200 nodB1 - - G - - - deacetylase
NNGKNKDC_00114 4.16e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNGKNKDC_00115 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NNGKNKDC_00116 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
NNGKNKDC_00117 4.46e-166 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NNGKNKDC_00118 1e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNGKNKDC_00119 1.44e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNGKNKDC_00120 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NNGKNKDC_00121 1.11e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNGKNKDC_00122 8.17e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNGKNKDC_00123 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NNGKNKDC_00124 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNGKNKDC_00125 1.86e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNGKNKDC_00126 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_00127 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
NNGKNKDC_00128 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
NNGKNKDC_00129 7.22e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNGKNKDC_00130 2.4e-315 yhdG - - E ko:K03294 - ko00000 amino acid
NNGKNKDC_00131 1.84e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_00132 9.47e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNGKNKDC_00133 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00134 5.07e-174 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNGKNKDC_00135 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NNGKNKDC_00136 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NNGKNKDC_00137 0.0 ygxB - - M - - - Conserved TM helix
NNGKNKDC_00138 3.79e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NNGKNKDC_00139 7.34e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNGKNKDC_00140 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
NNGKNKDC_00141 6.98e-53 yhdB - - S - - - YhdB-like protein
NNGKNKDC_00142 2.8e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NNGKNKDC_00143 2.22e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_00144 4.53e-264 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_00145 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NNGKNKDC_00146 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NNGKNKDC_00147 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNGKNKDC_00148 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNGKNKDC_00149 6.03e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NNGKNKDC_00150 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNGKNKDC_00151 1.36e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NNGKNKDC_00152 6.59e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NNGKNKDC_00153 1.74e-191 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_00154 7.8e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
NNGKNKDC_00155 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NNGKNKDC_00156 2.4e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NNGKNKDC_00157 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NNGKNKDC_00158 2.4e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_00159 1.57e-271 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_00160 4.19e-50 yraG - - - ko:K06440 - ko00000 -
NNGKNKDC_00161 3.35e-84 yraF - - M - - - Spore coat protein
NNGKNKDC_00162 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNGKNKDC_00163 3.54e-35 yraE - - - ko:K06440 - ko00000 -
NNGKNKDC_00164 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
NNGKNKDC_00165 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNGKNKDC_00166 7.15e-200 ydeK - - EG - - - -transporter
NNGKNKDC_00167 9.88e-132 ydeS - - K - - - Transcriptional regulator
NNGKNKDC_00168 1.52e-250 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NNGKNKDC_00170 3.59e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00171 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NNGKNKDC_00172 2.81e-281 nhaC_1 - - C - - - antiporter
NNGKNKDC_00173 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNGKNKDC_00174 3.68e-257 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NNGKNKDC_00175 1.77e-213 - - - S - - - Sodium Bile acid symporter family
NNGKNKDC_00176 1.69e-68 ydeH - - - - - - -
NNGKNKDC_00177 4.12e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NNGKNKDC_00179 1.73e-189 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
NNGKNKDC_00180 1.23e-86 ykkA - - S - - - Protein of unknown function (DUF664)
NNGKNKDC_00181 5.72e-126 yrkC - - G - - - Cupin domain
NNGKNKDC_00183 1.28e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NNGKNKDC_00184 2.26e-217 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NNGKNKDC_00185 1.99e-99 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_00186 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NNGKNKDC_00189 5.7e-64 - - - G - - - Cupin domain
NNGKNKDC_00190 6.11e-111 - - - S - - - DinB superfamily
NNGKNKDC_00191 2.51e-234 - - - S - - - Patatin-like phospholipase
NNGKNKDC_00192 2.24e-299 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_00193 9.07e-111 ybfA - - K - - - FR47-like protein
NNGKNKDC_00194 8.2e-68 - - - K - - - Transcriptional regulator PadR-like family
NNGKNKDC_00195 3e-133 - - - S - - - Protein of unknown function (DUF2812)
NNGKNKDC_00196 2.49e-157 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNGKNKDC_00197 7.2e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NNGKNKDC_00198 2.24e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NNGKNKDC_00199 2.99e-248 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NNGKNKDC_00200 1.67e-72 - - - K - - - Transcriptional regulator
NNGKNKDC_00201 7.67e-226 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NNGKNKDC_00202 1.13e-96 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NNGKNKDC_00203 0.0 - - - M - - - Domain of unknown function DUF11
NNGKNKDC_00204 1.58e-131 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNGKNKDC_00205 8.67e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNGKNKDC_00207 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NNGKNKDC_00208 1.94e-95 ywnA - - K - - - Transcriptional regulator
NNGKNKDC_00209 3.46e-84 - - - S - - - YjbR
NNGKNKDC_00210 8.69e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NNGKNKDC_00211 9.21e-75 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NNGKNKDC_00212 1.04e-65 ohrR - - K - - - Transcriptional regulator
NNGKNKDC_00213 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
NNGKNKDC_00214 7.99e-35 - - - G - - - Cupin domain
NNGKNKDC_00215 2.4e-192 - - - S - - - Serine aminopeptidase, S33
NNGKNKDC_00216 2.73e-92 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
NNGKNKDC_00217 1.81e-180 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
NNGKNKDC_00218 1.07e-94 - - - S - - - SnoaL-like polyketide cyclase
NNGKNKDC_00219 1.55e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
NNGKNKDC_00228 4.99e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NNGKNKDC_00229 1.78e-21 - - - - - - - -
NNGKNKDC_00230 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NNGKNKDC_00231 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NNGKNKDC_00232 9.33e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_00233 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NNGKNKDC_00234 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NNGKNKDC_00235 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NNGKNKDC_00236 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NNGKNKDC_00237 6.28e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NNGKNKDC_00238 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NNGKNKDC_00239 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NNGKNKDC_00240 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NNGKNKDC_00241 2.81e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNGKNKDC_00242 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NNGKNKDC_00243 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNGKNKDC_00244 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NNGKNKDC_00245 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NNGKNKDC_00246 2.78e-108 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NNGKNKDC_00247 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNGKNKDC_00248 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNGKNKDC_00249 1.25e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NNGKNKDC_00250 2.25e-74 ydbP - - CO - - - Thioredoxin
NNGKNKDC_00251 2.33e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNGKNKDC_00252 1.13e-15 - - - S - - - Fur-regulated basic protein B
NNGKNKDC_00253 1.07e-261 ydbM - - I - - - acyl-CoA dehydrogenase
NNGKNKDC_00254 1.32e-69 ydbL - - - - - - -
NNGKNKDC_00255 6.99e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNGKNKDC_00256 6.8e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00257 1.66e-228 ydbI - - S - - - AI-2E family transporter
NNGKNKDC_00258 1.59e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNGKNKDC_00259 1.75e-151 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NNGKNKDC_00260 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNGKNKDC_00261 4.46e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NNGKNKDC_00262 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
NNGKNKDC_00263 7.4e-82 ydbC - - S - - - Domain of unknown function (DUF4937
NNGKNKDC_00264 5.34e-78 ydbB - - G - - - Cupin domain
NNGKNKDC_00265 1.24e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
NNGKNKDC_00266 1.88e-182 ydbA - - P - - - EcsC protein family
NNGKNKDC_00267 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NNGKNKDC_00268 1.03e-91 yvaD - - S - - - Family of unknown function (DUF5360)
NNGKNKDC_00269 1.13e-44 ydaT - - - - - - -
NNGKNKDC_00271 2.28e-289 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NNGKNKDC_00272 2.14e-53 - - - - - - - -
NNGKNKDC_00273 7.01e-129 - - - - - - - -
NNGKNKDC_00274 6.95e-112 - - - - - - - -
NNGKNKDC_00276 1.49e-26 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NNGKNKDC_00277 3.17e-46 xkdS - - S - - - Protein of unknown function (DUF2634)
NNGKNKDC_00278 9.37e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNGKNKDC_00279 2.08e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
NNGKNKDC_00280 6.86e-109 xkdQ - - G - - - NLP P60 protein
NNGKNKDC_00282 1.5e-21 - - - - - - - -
NNGKNKDC_00283 1.7e-87 - - - K - - - acetyltransferase
NNGKNKDC_00284 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNGKNKDC_00285 3.21e-99 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NNGKNKDC_00286 0.0 ydaO - - E - - - amino acid
NNGKNKDC_00287 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NNGKNKDC_00288 7.53e-302 ydaM - - M - - - Glycosyl transferase family group 2
NNGKNKDC_00289 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NNGKNKDC_00290 1.32e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NNGKNKDC_00291 1.56e-255 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NNGKNKDC_00292 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNGKNKDC_00293 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NNGKNKDC_00294 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NNGKNKDC_00295 2.06e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
NNGKNKDC_00296 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NNGKNKDC_00297 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNGKNKDC_00298 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NNGKNKDC_00299 5.4e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NNGKNKDC_00300 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NNGKNKDC_00301 1.34e-152 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NNGKNKDC_00302 2.82e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNGKNKDC_00303 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
NNGKNKDC_00304 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNGKNKDC_00305 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
NNGKNKDC_00306 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNGKNKDC_00307 5.69e-238 yrrI - - S - - - AI-2E family transporter
NNGKNKDC_00308 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNGKNKDC_00309 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNGKNKDC_00310 1.95e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKNKDC_00311 1.87e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKNKDC_00312 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
NNGKNKDC_00313 8.4e-42 yrzR - - - - - - -
NNGKNKDC_00314 1.76e-107 yrrD - - S - - - protein conserved in bacteria
NNGKNKDC_00315 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNGKNKDC_00316 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
NNGKNKDC_00317 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNGKNKDC_00318 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNGKNKDC_00319 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00320 3.74e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NNGKNKDC_00321 2.39e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NNGKNKDC_00322 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NNGKNKDC_00323 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NNGKNKDC_00326 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NNGKNKDC_00327 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNGKNKDC_00328 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNGKNKDC_00329 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNGKNKDC_00330 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NNGKNKDC_00331 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NNGKNKDC_00332 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NNGKNKDC_00333 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NNGKNKDC_00334 3.33e-66 yrzD - - S - - - Post-transcriptional regulator
NNGKNKDC_00335 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_00336 2.03e-143 yrbG - - S - - - membrane
NNGKNKDC_00337 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
NNGKNKDC_00338 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NNGKNKDC_00339 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNGKNKDC_00340 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNGKNKDC_00341 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
NNGKNKDC_00342 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNGKNKDC_00343 2.33e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNGKNKDC_00344 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NNGKNKDC_00346 7.24e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNGKNKDC_00347 1.31e-257 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NNGKNKDC_00348 1.73e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NNGKNKDC_00349 1.75e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NNGKNKDC_00350 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NNGKNKDC_00351 3.31e-284 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNGKNKDC_00352 9.72e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NNGKNKDC_00353 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NNGKNKDC_00354 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NNGKNKDC_00355 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNGKNKDC_00356 3.5e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NNGKNKDC_00357 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NNGKNKDC_00358 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NNGKNKDC_00359 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NNGKNKDC_00360 4.19e-205 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NNGKNKDC_00361 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NNGKNKDC_00362 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NNGKNKDC_00363 4.09e-131 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNGKNKDC_00364 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NNGKNKDC_00365 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NNGKNKDC_00366 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NNGKNKDC_00367 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NNGKNKDC_00368 4.77e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NNGKNKDC_00369 2.55e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NNGKNKDC_00370 1.62e-134 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NNGKNKDC_00371 1.79e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NNGKNKDC_00372 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNGKNKDC_00373 1.53e-35 - - - - - - - -
NNGKNKDC_00374 5.42e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NNGKNKDC_00375 2.96e-304 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NNGKNKDC_00376 3.8e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NNGKNKDC_00377 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NNGKNKDC_00378 3.98e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NNGKNKDC_00379 1.22e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NNGKNKDC_00380 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NNGKNKDC_00381 1.24e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NNGKNKDC_00382 2.28e-113 ysxD - - - - - - -
NNGKNKDC_00383 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NNGKNKDC_00384 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NNGKNKDC_00385 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NNGKNKDC_00386 1.34e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNGKNKDC_00387 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNGKNKDC_00388 3.33e-241 ysoA - - H - - - Tetratricopeptide repeat
NNGKNKDC_00389 1.08e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNGKNKDC_00390 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNGKNKDC_00391 8.67e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NNGKNKDC_00392 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NNGKNKDC_00393 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NNGKNKDC_00394 6.88e-108 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NNGKNKDC_00395 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NNGKNKDC_00400 1.36e-117 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NNGKNKDC_00401 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNGKNKDC_00402 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NNGKNKDC_00403 4.47e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NNGKNKDC_00404 4.68e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NNGKNKDC_00405 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_00406 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00407 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NNGKNKDC_00408 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NNGKNKDC_00409 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NNGKNKDC_00410 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NNGKNKDC_00411 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
NNGKNKDC_00412 8.64e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNGKNKDC_00413 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNGKNKDC_00414 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNGKNKDC_00415 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NNGKNKDC_00416 7.11e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NNGKNKDC_00417 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NNGKNKDC_00418 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NNGKNKDC_00419 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00420 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNGKNKDC_00421 9.73e-152 ywbB - - S - - - Protein of unknown function (DUF2711)
NNGKNKDC_00422 2.56e-115 yisT - - S - - - DinB family
NNGKNKDC_00423 1.03e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NNGKNKDC_00424 1.02e-240 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNGKNKDC_00425 7.94e-104 yisX - - S - - - Pentapeptide repeats (9 copies)
NNGKNKDC_00426 2.99e-103 - - - S - - - Acetyltransferase (GNAT) domain
NNGKNKDC_00427 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NNGKNKDC_00428 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NNGKNKDC_00429 2.63e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NNGKNKDC_00430 2.97e-219 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
NNGKNKDC_00431 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NNGKNKDC_00432 7.6e-309 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NNGKNKDC_00434 5.5e-203 yitS - - S - - - protein conserved in bacteria
NNGKNKDC_00435 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_00436 8.76e-104 ipi - - S - - - Intracellular proteinase inhibitor
NNGKNKDC_00437 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
NNGKNKDC_00438 1.49e-11 - - - - - - - -
NNGKNKDC_00439 8.78e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NNGKNKDC_00440 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNGKNKDC_00441 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NNGKNKDC_00442 1.37e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NNGKNKDC_00443 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NNGKNKDC_00444 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
NNGKNKDC_00445 2.78e-250 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NNGKNKDC_00446 5.17e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NNGKNKDC_00447 1.22e-173 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NNGKNKDC_00448 8.03e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NNGKNKDC_00449 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNGKNKDC_00450 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NNGKNKDC_00451 8.28e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NNGKNKDC_00452 7.21e-39 yjzC - - S - - - YjzC-like protein
NNGKNKDC_00453 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
NNGKNKDC_00454 9.07e-178 yjaU - - I - - - carboxylic ester hydrolase activity
NNGKNKDC_00455 9.68e-134 yjaV - - - - - - -
NNGKNKDC_00456 3.84e-212 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NNGKNKDC_00457 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NNGKNKDC_00458 2.82e-44 yjzB - - - - - - -
NNGKNKDC_00459 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNGKNKDC_00460 6.39e-299 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNGKNKDC_00461 7.48e-190 yjaZ - - O - - - Zn-dependent protease
NNGKNKDC_00462 6.88e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00463 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00464 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NNGKNKDC_00465 5.76e-217 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_00466 1.67e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_00467 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
NNGKNKDC_00468 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NNGKNKDC_00469 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNGKNKDC_00470 1.2e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_00471 1.2e-208 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_00472 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00473 1.04e-218 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00474 3.39e-296 - - - S - - - Putative glycosyl hydrolase domain
NNGKNKDC_00475 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKNKDC_00476 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNGKNKDC_00477 9.66e-142 yjbE - - P - - - Integral membrane protein TerC family
NNGKNKDC_00478 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNGKNKDC_00479 2.42e-283 coiA - - S ko:K06198 - ko00000 Competence protein
NNGKNKDC_00480 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NNGKNKDC_00481 3.14e-27 - - - - - - - -
NNGKNKDC_00482 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NNGKNKDC_00483 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NNGKNKDC_00484 1.04e-150 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNGKNKDC_00485 1.21e-128 yjbK - - S - - - protein conserved in bacteria
NNGKNKDC_00486 4.78e-79 yjbL - - S - - - Belongs to the UPF0738 family
NNGKNKDC_00487 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NNGKNKDC_00488 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNGKNKDC_00489 9.96e-213 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNGKNKDC_00490 8.74e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NNGKNKDC_00491 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNGKNKDC_00492 8.72e-174 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NNGKNKDC_00493 9.45e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NNGKNKDC_00494 3.35e-270 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NNGKNKDC_00495 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
NNGKNKDC_00496 5.18e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NNGKNKDC_00497 9.55e-242 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNGKNKDC_00498 1.5e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNGKNKDC_00499 1.96e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NNGKNKDC_00500 1.68e-125 yjbX - - S - - - Spore coat protein
NNGKNKDC_00501 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NNGKNKDC_00502 5.2e-122 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NNGKNKDC_00503 6.68e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NNGKNKDC_00504 1.98e-36 cotW - - - ko:K06341 - ko00000 -
NNGKNKDC_00505 3.02e-74 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NNGKNKDC_00506 2.92e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
NNGKNKDC_00509 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNGKNKDC_00510 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
NNGKNKDC_00511 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNGKNKDC_00512 5e-48 - - - - - - - -
NNGKNKDC_00513 7.48e-184 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NNGKNKDC_00514 4.4e-158 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNGKNKDC_00515 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNGKNKDC_00516 4.32e-48 - - - K - - - SpoVT / AbrB like domain
NNGKNKDC_00517 2.12e-97 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKNKDC_00518 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NNGKNKDC_00519 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NNGKNKDC_00520 2.01e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNGKNKDC_00521 2.48e-274 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNGKNKDC_00523 2.74e-06 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NNGKNKDC_00524 2.19e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NNGKNKDC_00525 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NNGKNKDC_00526 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNGKNKDC_00527 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NNGKNKDC_00528 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NNGKNKDC_00529 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NNGKNKDC_00530 8.28e-67 yerC - - S - - - protein conserved in bacteria
NNGKNKDC_00531 1.73e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NNGKNKDC_00532 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NNGKNKDC_00533 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
NNGKNKDC_00534 1.99e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NNGKNKDC_00535 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NNGKNKDC_00536 8.53e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNGKNKDC_00537 5.11e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NNGKNKDC_00538 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNGKNKDC_00539 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKNKDC_00540 7.78e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKNKDC_00541 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNGKNKDC_00542 2.04e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NNGKNKDC_00543 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNGKNKDC_00544 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNGKNKDC_00545 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNGKNKDC_00546 2.21e-38 yebG - - S - - - NETI protein
NNGKNKDC_00547 2.66e-120 yebE - - S - - - UPF0316 protein
NNGKNKDC_00549 1.03e-166 yebC - - M - - - Membrane
NNGKNKDC_00550 5.02e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NNGKNKDC_00551 3.21e-315 - - - S - - - Domain of unknown function (DUF4179)
NNGKNKDC_00552 1.15e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_00553 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NNGKNKDC_00554 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NNGKNKDC_00555 6.6e-276 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NNGKNKDC_00556 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NNGKNKDC_00557 1.68e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNGKNKDC_00558 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_00559 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NNGKNKDC_00560 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
NNGKNKDC_00562 3.35e-193 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NNGKNKDC_00563 3.92e-83 ydjM - - M - - - Lytic transglycolase
NNGKNKDC_00564 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NNGKNKDC_00565 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_00566 1.54e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
NNGKNKDC_00567 0.0 oatA - - I - - - Acyltransferase family
NNGKNKDC_00568 5.57e-224 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NNGKNKDC_00569 6.7e-164 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NNGKNKDC_00570 2.99e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNGKNKDC_00571 1.17e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NNGKNKDC_00572 4.9e-39 yjdJ - - S - - - Domain of unknown function (DUF4306)
NNGKNKDC_00573 5.17e-222 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NNGKNKDC_00574 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NNGKNKDC_00575 9.75e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NNGKNKDC_00576 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NNGKNKDC_00577 8.97e-192 ydjC - - S - - - Abhydrolase domain containing 18
NNGKNKDC_00578 1.3e-171 - - - KL - - - Type III restriction enzyme res subunit
NNGKNKDC_00579 6.87e-200 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
NNGKNKDC_00580 3.53e-20 - - - - - - - -
NNGKNKDC_00581 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNGKNKDC_00582 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNGKNKDC_00583 1.17e-164 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNGKNKDC_00584 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NNGKNKDC_00585 3.33e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNGKNKDC_00586 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNGKNKDC_00587 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNGKNKDC_00588 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NNGKNKDC_00589 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NNGKNKDC_00590 5.33e-244 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNGKNKDC_00591 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNGKNKDC_00592 4.14e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NNGKNKDC_00593 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NNGKNKDC_00594 4e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NNGKNKDC_00596 2.54e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NNGKNKDC_00597 7.45e-101 ydaG - - S - - - general stress protein
NNGKNKDC_00598 5.73e-149 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNGKNKDC_00599 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NNGKNKDC_00600 2.21e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_00601 0.0 ydaB - - IQ - - - acyl-CoA ligase
NNGKNKDC_00602 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NNGKNKDC_00603 7.36e-221 ycsN - - S - - - Oxidoreductase
NNGKNKDC_00604 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NNGKNKDC_00605 2.42e-74 yczJ - - S - - - biosynthesis
NNGKNKDC_00607 9.47e-151 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NNGKNKDC_00608 4.65e-167 kipR - - K - - - Transcriptional regulator
NNGKNKDC_00609 1.2e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NNGKNKDC_00610 4.86e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NNGKNKDC_00611 5.08e-194 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NNGKNKDC_00612 6.53e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NNGKNKDC_00613 2.49e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NNGKNKDC_00614 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NNGKNKDC_00616 6.81e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NNGKNKDC_00617 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NNGKNKDC_00618 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NNGKNKDC_00619 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NNGKNKDC_00620 1.59e-71 - - - - - - - -
NNGKNKDC_00621 7.07e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNGKNKDC_00622 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NNGKNKDC_00623 2.05e-131 ycnI - - S - - - protein conserved in bacteria
NNGKNKDC_00624 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_00625 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NNGKNKDC_00626 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNGKNKDC_00627 7.59e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNGKNKDC_00628 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNGKNKDC_00629 3.92e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKNKDC_00630 9.74e-60 ycnE - - S - - - Monooxygenase
NNGKNKDC_00631 2.39e-175 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
NNGKNKDC_00632 7.4e-196 ycnC - - K - - - Transcriptional regulator
NNGKNKDC_00633 6.91e-314 ycnB - - EGP - - - the major facilitator superfamily
NNGKNKDC_00634 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NNGKNKDC_00635 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00636 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_00637 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_00638 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNGKNKDC_00640 5.98e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNGKNKDC_00641 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
NNGKNKDC_00642 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_00643 5.45e-313 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NNGKNKDC_00644 4.46e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NNGKNKDC_00645 0.0 yxeQ - - S - - - MmgE/PrpD family
NNGKNKDC_00646 1.39e-276 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NNGKNKDC_00647 9.29e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00648 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNGKNKDC_00649 5.21e-182 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNGKNKDC_00650 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKNKDC_00651 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_00652 6.5e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NNGKNKDC_00653 3.43e-301 gerKC - - S ko:K06297 - ko00000 spore germination
NNGKNKDC_00654 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NNGKNKDC_00656 0.0 yclG - - M - - - Pectate lyase superfamily protein
NNGKNKDC_00657 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NNGKNKDC_00658 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NNGKNKDC_00659 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NNGKNKDC_00660 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NNGKNKDC_00661 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NNGKNKDC_00662 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNGKNKDC_00663 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NNGKNKDC_00664 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NNGKNKDC_00665 8.31e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NNGKNKDC_00666 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NNGKNKDC_00667 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNGKNKDC_00668 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NNGKNKDC_00669 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNGKNKDC_00670 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNGKNKDC_00671 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNGKNKDC_00672 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NNGKNKDC_00673 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NNGKNKDC_00674 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNGKNKDC_00675 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNGKNKDC_00676 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNGKNKDC_00677 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNGKNKDC_00678 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNGKNKDC_00679 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNGKNKDC_00680 1.2e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NNGKNKDC_00681 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKNKDC_00682 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKNKDC_00683 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NNGKNKDC_00684 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNGKNKDC_00685 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNGKNKDC_00686 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNGKNKDC_00687 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNGKNKDC_00688 1.16e-239 ybaC - - S - - - Alpha/beta hydrolase family
NNGKNKDC_00689 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NNGKNKDC_00690 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNGKNKDC_00691 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NNGKNKDC_00692 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNGKNKDC_00693 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNGKNKDC_00694 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNGKNKDC_00695 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNGKNKDC_00696 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNGKNKDC_00697 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNGKNKDC_00698 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NNGKNKDC_00699 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNGKNKDC_00700 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNGKNKDC_00701 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNGKNKDC_00702 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNGKNKDC_00703 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNGKNKDC_00704 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNGKNKDC_00705 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNGKNKDC_00706 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNGKNKDC_00707 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNGKNKDC_00708 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NNGKNKDC_00709 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NNGKNKDC_00710 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNGKNKDC_00711 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNGKNKDC_00712 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NNGKNKDC_00713 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNGKNKDC_00714 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NNGKNKDC_00715 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNGKNKDC_00716 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNGKNKDC_00717 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNGKNKDC_00718 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NNGKNKDC_00719 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKNKDC_00720 2.43e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKNKDC_00721 1.13e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNGKNKDC_00722 7.18e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNGKNKDC_00723 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNGKNKDC_00724 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NNGKNKDC_00725 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
NNGKNKDC_00726 3.15e-108 yizA - - S - - - Damage-inducible protein DinB
NNGKNKDC_00727 3.22e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
NNGKNKDC_00728 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNGKNKDC_00729 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NNGKNKDC_00730 1.95e-102 gerD - - - ko:K06294 - ko00000 -
NNGKNKDC_00731 1.78e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NNGKNKDC_00732 1.83e-182 pdaB - - G - - - Polysaccharide deacetylase
NNGKNKDC_00733 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NNGKNKDC_00734 2.93e-136 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NNGKNKDC_00735 3.44e-244 yaaN - - P - - - Belongs to the TelA family
NNGKNKDC_00736 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NNGKNKDC_00737 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNGKNKDC_00738 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
NNGKNKDC_00739 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NNGKNKDC_00740 3.29e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNGKNKDC_00741 9e-189 yaaT - - S - - - stage 0 sporulation protein
NNGKNKDC_00742 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NNGKNKDC_00743 8.39e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NNGKNKDC_00744 4.03e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NNGKNKDC_00745 1.41e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNGKNKDC_00746 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NNGKNKDC_00747 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNGKNKDC_00748 1.5e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NNGKNKDC_00749 2.04e-309 yabE - - T - - - protein conserved in bacteria
NNGKNKDC_00750 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNGKNKDC_00751 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNGKNKDC_00752 5.75e-209 yabG - - S ko:K06436 - ko00000 peptidase
NNGKNKDC_00753 3.08e-52 veg - - S - - - protein conserved in bacteria
NNGKNKDC_00754 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
NNGKNKDC_00755 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNGKNKDC_00756 1.82e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NNGKNKDC_00757 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NNGKNKDC_00758 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NNGKNKDC_00759 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNGKNKDC_00760 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNGKNKDC_00761 6.18e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NNGKNKDC_00762 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNGKNKDC_00763 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
NNGKNKDC_00764 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNGKNKDC_00765 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NNGKNKDC_00766 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_00767 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NNGKNKDC_00768 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NNGKNKDC_00769 5.47e-66 yabP - - S - - - Sporulation protein YabP
NNGKNKDC_00770 1.37e-133 yabQ - - S - - - spore cortex biosynthesis protein
NNGKNKDC_00771 1.7e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NNGKNKDC_00772 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NNGKNKDC_00775 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NNGKNKDC_00776 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNGKNKDC_00777 1.64e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNGKNKDC_00778 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNGKNKDC_00779 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NNGKNKDC_00780 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNGKNKDC_00781 5.46e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NNGKNKDC_00782 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNGKNKDC_00783 1.19e-199 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NNGKNKDC_00784 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNGKNKDC_00785 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNGKNKDC_00786 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NNGKNKDC_00787 1.71e-207 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NNGKNKDC_00788 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NNGKNKDC_00789 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NNGKNKDC_00790 9.58e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NNGKNKDC_00791 8.67e-40 yazB - - K - - - transcriptional
NNGKNKDC_00792 8.82e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNGKNKDC_00793 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NNGKNKDC_00801 0.0 - - - C - - - Na+/H+ antiporter family
NNGKNKDC_00802 1.78e-88 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NNGKNKDC_00803 1.74e-64 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NNGKNKDC_00804 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NNGKNKDC_00805 0.0 ygaK - - C - - - Berberine and berberine like
NNGKNKDC_00807 7.75e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
NNGKNKDC_00808 2.97e-188 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKNKDC_00809 2.4e-159 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_00810 1.34e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00811 1.15e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_00812 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNGKNKDC_00813 1.13e-235 - - - S ko:K07045 - ko00000 Amidohydrolase
NNGKNKDC_00814 7.45e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NNGKNKDC_00815 1.06e-230 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NNGKNKDC_00816 5.58e-184 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNGKNKDC_00817 1.43e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NNGKNKDC_00818 3.39e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNGKNKDC_00819 2.6e-106 ygaO - - - - - - -
NNGKNKDC_00820 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00822 4.53e-146 yhzB - - S - - - B3/4 domain
NNGKNKDC_00823 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNGKNKDC_00824 2.13e-226 yhbB - - S - - - Putative amidase domain
NNGKNKDC_00825 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNGKNKDC_00826 2.3e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
NNGKNKDC_00827 8.53e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NNGKNKDC_00828 1.16e-93 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NNGKNKDC_00829 1.23e-07 - - - - - - - -
NNGKNKDC_00830 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NNGKNKDC_00831 1.77e-280 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NNGKNKDC_00832 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NNGKNKDC_00833 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NNGKNKDC_00834 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NNGKNKDC_00835 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNGKNKDC_00836 1.41e-72 yhcC - - - - - - -
NNGKNKDC_00837 3.3e-66 - - - - - - - -
NNGKNKDC_00838 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_00839 1.03e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00840 3.9e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00841 1.83e-208 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNGKNKDC_00842 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NNGKNKDC_00843 2.29e-187 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNGKNKDC_00844 2.48e-235 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NNGKNKDC_00845 3.7e-293 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNGKNKDC_00846 1.96e-77 yhcM - - - - - - -
NNGKNKDC_00847 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNGKNKDC_00848 2.74e-206 yhcP - - - - - - -
NNGKNKDC_00849 1.09e-151 yhcQ - - M - - - Spore coat protein
NNGKNKDC_00850 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NNGKNKDC_00851 1.3e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NNGKNKDC_00852 5.35e-215 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNGKNKDC_00853 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
NNGKNKDC_00854 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
NNGKNKDC_00855 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
NNGKNKDC_00856 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNGKNKDC_00863 1.01e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NNGKNKDC_00864 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
NNGKNKDC_00865 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NNGKNKDC_00866 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NNGKNKDC_00867 3.07e-200 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NNGKNKDC_00868 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNGKNKDC_00869 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNGKNKDC_00870 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNGKNKDC_00871 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NNGKNKDC_00872 3.16e-236 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NNGKNKDC_00873 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NNGKNKDC_00874 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NNGKNKDC_00875 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NNGKNKDC_00876 1.99e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NNGKNKDC_00877 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNGKNKDC_00878 3.62e-100 ytkA - - S - - - YtkA-like
NNGKNKDC_00880 2.56e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NNGKNKDC_00881 1.23e-79 ytkC - - S - - - Bacteriophage holin family
NNGKNKDC_00882 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NNGKNKDC_00883 2.19e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NNGKNKDC_00884 1.06e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNGKNKDC_00885 1.84e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NNGKNKDC_00886 3.17e-189 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NNGKNKDC_00887 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
NNGKNKDC_00888 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NNGKNKDC_00889 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNGKNKDC_00890 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNGKNKDC_00891 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_00892 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NNGKNKDC_00893 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NNGKNKDC_00894 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NNGKNKDC_00895 1.56e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
NNGKNKDC_00897 6.26e-137 ytqB - - J - - - Putative rRNA methylase
NNGKNKDC_00898 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NNGKNKDC_00899 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_00900 1.45e-169 aveG - - Q - - - Thioesterase domain
NNGKNKDC_00901 3.89e-241 - - - C - - - Nitroreductase
NNGKNKDC_00903 2.43e-125 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NNGKNKDC_00904 1.45e-275 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NNGKNKDC_00905 5.61e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NNGKNKDC_00906 5.37e-107 yuaE - - S - - - DinB superfamily
NNGKNKDC_00907 6.79e-141 - - - S - - - MOSC domain
NNGKNKDC_00908 7.08e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NNGKNKDC_00909 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNGKNKDC_00910 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NNGKNKDC_00911 2.03e-122 yuaB - - - - - - -
NNGKNKDC_00912 6.13e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NNGKNKDC_00913 6.61e-194 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNGKNKDC_00914 1.03e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NNGKNKDC_00915 2.25e-158 - - - G - - - Cupin
NNGKNKDC_00916 1.63e-14 yjcN - - - - - - -
NNGKNKDC_00918 9.34e-21 - - - - - - - -
NNGKNKDC_00919 1.35e-231 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NNGKNKDC_00922 1.14e-15 - - - K - - - Helix-turn-helix domain
NNGKNKDC_00925 9.56e-49 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
NNGKNKDC_00926 1.42e-39 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NNGKNKDC_00928 2.67e-186 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NNGKNKDC_00929 9.96e-251 yubA - - S - - - transporter activity
NNGKNKDC_00930 1.57e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NNGKNKDC_00931 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NNGKNKDC_00932 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNGKNKDC_00933 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNGKNKDC_00934 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNGKNKDC_00935 2.76e-298 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNGKNKDC_00936 2.22e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NNGKNKDC_00937 1.61e-55 - - - - - - - -
NNGKNKDC_00938 1.65e-241 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NNGKNKDC_00939 9.38e-99 yugU - - S - - - Uncharacterised protein family UPF0047
NNGKNKDC_00940 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNGKNKDC_00941 2.31e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNGKNKDC_00942 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NNGKNKDC_00943 1.24e-22 - - - - - - - -
NNGKNKDC_00944 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
NNGKNKDC_00945 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NNGKNKDC_00946 8.53e-95 yugN - - S - - - YugN-like family
NNGKNKDC_00948 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NNGKNKDC_00949 1.95e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NNGKNKDC_00950 1.77e-151 ycaC - - Q - - - Isochorismatase family
NNGKNKDC_00951 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NNGKNKDC_00952 1.11e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NNGKNKDC_00953 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NNGKNKDC_00954 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NNGKNKDC_00955 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NNGKNKDC_00956 3.75e-109 alaR - - K - - - Transcriptional regulator
NNGKNKDC_00957 9.5e-199 yugF - - I - - - Hydrolase
NNGKNKDC_00958 1.67e-52 yugE - - S - - - Domain of unknown function (DUF1871)
NNGKNKDC_00959 1.11e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NNGKNKDC_00960 2.88e-289 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_00961 2.4e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NNGKNKDC_00962 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NNGKNKDC_00963 2.62e-263 yuxJ - - EGP - - - Major facilitator superfamily
NNGKNKDC_00964 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NNGKNKDC_00965 1.52e-94 yuxK - - S - - - protein conserved in bacteria
NNGKNKDC_00966 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
NNGKNKDC_00967 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNGKNKDC_00968 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NNGKNKDC_00969 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NNGKNKDC_00970 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_00971 9.08e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNGKNKDC_00972 1.26e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNGKNKDC_00974 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NNGKNKDC_00975 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNGKNKDC_00976 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNGKNKDC_00977 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNGKNKDC_00978 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNGKNKDC_00979 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNGKNKDC_00980 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NNGKNKDC_00981 1.45e-85 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NNGKNKDC_00982 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_00983 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_00985 2.49e-196 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
NNGKNKDC_00986 2.66e-11 - - - S - - - DegQ (SacQ) family
NNGKNKDC_00987 4.94e-66 yuzC - - - - - - -
NNGKNKDC_00988 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NNGKNKDC_00989 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNGKNKDC_00990 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NNGKNKDC_00991 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
NNGKNKDC_00992 5.46e-51 yueH - - S - - - YueH-like protein
NNGKNKDC_00993 1.05e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NNGKNKDC_00994 1.47e-235 yueF - - S - - - transporter activity
NNGKNKDC_00995 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
NNGKNKDC_00996 2.61e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NNGKNKDC_00997 1.44e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_00998 1.09e-99 yueC - - S - - - Family of unknown function (DUF5383)
NNGKNKDC_00999 0.0 yueB - - S - - - type VII secretion protein EsaA
NNGKNKDC_01000 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NNGKNKDC_01001 1.53e-273 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NNGKNKDC_01002 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NNGKNKDC_01003 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
NNGKNKDC_01004 4.26e-291 yukF - - QT - - - Transcriptional regulator
NNGKNKDC_01005 9.45e-260 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NNGKNKDC_01006 4.18e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NNGKNKDC_01007 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NNGKNKDC_01008 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_01009 6.8e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NNGKNKDC_01010 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NNGKNKDC_01011 1.3e-284 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NNGKNKDC_01012 7.08e-171 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_01013 1.47e-210 eSD - - S ko:K07017 - ko00000 Putative esterase
NNGKNKDC_01014 1.32e-154 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NNGKNKDC_01015 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NNGKNKDC_01016 8.19e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NNGKNKDC_01017 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NNGKNKDC_01018 1.18e-99 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NNGKNKDC_01019 9.86e-153 yuiC - - S - - - protein conserved in bacteria
NNGKNKDC_01020 2.45e-45 yuiB - - S - - - Putative membrane protein
NNGKNKDC_01021 3.42e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNGKNKDC_01022 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NNGKNKDC_01024 6.68e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNGKNKDC_01025 5.68e-40 - - - - - - - -
NNGKNKDC_01026 4.86e-92 - - - CP - - - Membrane
NNGKNKDC_01027 1.32e-156 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNGKNKDC_01029 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
NNGKNKDC_01031 1.69e-121 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NNGKNKDC_01032 1.82e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_01033 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NNGKNKDC_01034 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNGKNKDC_01035 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNGKNKDC_01036 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NNGKNKDC_01037 1.2e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNGKNKDC_01038 2.81e-74 yuzD - - S - - - protein conserved in bacteria
NNGKNKDC_01039 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NNGKNKDC_01040 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NNGKNKDC_01041 7.89e-216 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNGKNKDC_01042 3.81e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NNGKNKDC_01043 2.76e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NNGKNKDC_01044 1.55e-250 yutH - - S - - - Spore coat protein
NNGKNKDC_01045 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NNGKNKDC_01046 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNGKNKDC_01047 2.2e-95 yutE - - S - - - Protein of unknown function DUF86
NNGKNKDC_01048 2.15e-61 yutD - - S - - - protein conserved in bacteria
NNGKNKDC_01049 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NNGKNKDC_01050 3.92e-249 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NNGKNKDC_01051 9.21e-166 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NNGKNKDC_01052 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NNGKNKDC_01053 4.27e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NNGKNKDC_01054 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
NNGKNKDC_01055 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
NNGKNKDC_01056 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NNGKNKDC_01057 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NNGKNKDC_01059 3.52e-227 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NNGKNKDC_01060 2.6e-84 - - - - - - - -
NNGKNKDC_01061 5.21e-275 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_01062 1.71e-301 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NNGKNKDC_01063 2.31e-297 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NNGKNKDC_01064 1.66e-216 bsn - - L - - - Ribonuclease
NNGKNKDC_01065 4.53e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_01066 1.19e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NNGKNKDC_01067 2.16e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NNGKNKDC_01068 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NNGKNKDC_01069 4.14e-200 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKNKDC_01070 6.42e-286 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NNGKNKDC_01071 1.57e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NNGKNKDC_01073 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NNGKNKDC_01074 9.09e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NNGKNKDC_01075 8.89e-165 - - - Q - - - ubiE/COQ5 methyltransferase family
NNGKNKDC_01076 3.71e-105 yncE - - S - - - Protein of unknown function (DUF2691)
NNGKNKDC_01077 1.03e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NNGKNKDC_01078 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NNGKNKDC_01079 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NNGKNKDC_01080 9.4e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNGKNKDC_01081 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NNGKNKDC_01082 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NNGKNKDC_01083 1.47e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NNGKNKDC_01084 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NNGKNKDC_01085 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NNGKNKDC_01086 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNGKNKDC_01087 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
NNGKNKDC_01088 1.64e-72 yusE - - CO - - - Thioredoxin
NNGKNKDC_01089 1.26e-81 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NNGKNKDC_01090 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
NNGKNKDC_01091 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NNGKNKDC_01092 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NNGKNKDC_01093 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NNGKNKDC_01094 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NNGKNKDC_01095 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NNGKNKDC_01096 5.35e-215 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NNGKNKDC_01097 2.25e-58 - - - - - - - -
NNGKNKDC_01098 4.46e-72 yusN - - M - - - Coat F domain
NNGKNKDC_01099 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NNGKNKDC_01100 0.0 yusP - - P - - - Major facilitator superfamily
NNGKNKDC_01101 7.21e-205 - - - K - - - Transcriptional regulator
NNGKNKDC_01102 5.88e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NNGKNKDC_01103 5.11e-242 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNGKNKDC_01104 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
NNGKNKDC_01105 5.24e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNGKNKDC_01106 1.32e-60 - - - S - - - YusW-like protein
NNGKNKDC_01107 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NNGKNKDC_01108 9.07e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_01109 1.18e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NNGKNKDC_01110 8.52e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNGKNKDC_01111 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_01112 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_01113 2.68e-32 - - - - - - - -
NNGKNKDC_01114 1.8e-200 yuxN - - K - - - Transcriptional regulator
NNGKNKDC_01115 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNGKNKDC_01116 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
NNGKNKDC_01117 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NNGKNKDC_01118 2.16e-244 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NNGKNKDC_01119 4.66e-257 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NNGKNKDC_01120 1.68e-138 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_01121 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_01122 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NNGKNKDC_01123 1.17e-191 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NNGKNKDC_01124 2.29e-132 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NNGKNKDC_01125 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NNGKNKDC_01126 2.77e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_01127 7.62e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NNGKNKDC_01128 1.41e-284 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NNGKNKDC_01129 1.87e-229 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_01130 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNGKNKDC_01131 4.99e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_01132 6.55e-220 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NNGKNKDC_01133 0.0 yvrG - - T - - - Histidine kinase
NNGKNKDC_01134 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_01135 1.67e-50 - - - - - - - -
NNGKNKDC_01136 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NNGKNKDC_01137 1.88e-21 - - - S - - - YvrJ protein family
NNGKNKDC_01138 1.27e-294 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NNGKNKDC_01139 3.41e-88 yvrL - - S - - - Regulatory protein YrvL
NNGKNKDC_01140 2.09e-159 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NNGKNKDC_01141 3.01e-68 - - - L - - - transposase activity
NNGKNKDC_01142 2.8e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNGKNKDC_01143 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_01144 9.43e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_01145 2.59e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNGKNKDC_01146 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NNGKNKDC_01147 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NNGKNKDC_01148 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NNGKNKDC_01149 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NNGKNKDC_01150 7e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NNGKNKDC_01151 8.27e-180 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NNGKNKDC_01152 2.33e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NNGKNKDC_01153 1.76e-147 yfiK - - K - - - Regulator
NNGKNKDC_01154 6.98e-131 - - - T - - - Histidine kinase
NNGKNKDC_01155 4.02e-80 - - - T - - - Histidine kinase
NNGKNKDC_01156 5.8e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NNGKNKDC_01157 2.46e-249 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNGKNKDC_01158 9.4e-258 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NNGKNKDC_01159 1.77e-200 yvgN - - S - - - reductase
NNGKNKDC_01160 7.97e-113 yvgO - - - - - - -
NNGKNKDC_01161 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NNGKNKDC_01162 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NNGKNKDC_01163 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NNGKNKDC_01164 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNGKNKDC_01165 1.3e-138 yvgT - - S - - - membrane
NNGKNKDC_01166 8.08e-192 - - - S - - - Metallo-peptidase family M12
NNGKNKDC_01167 2.14e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NNGKNKDC_01168 3.33e-140 bdbD - - O - - - Thioredoxin
NNGKNKDC_01169 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NNGKNKDC_01170 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NNGKNKDC_01171 1.88e-39 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
NNGKNKDC_01172 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NNGKNKDC_01173 2.76e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NNGKNKDC_01174 4.19e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNGKNKDC_01175 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_01176 7.12e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NNGKNKDC_01177 1.44e-231 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_01178 4.28e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNGKNKDC_01179 8.24e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKNKDC_01180 8.5e-156 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKNKDC_01181 5.86e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NNGKNKDC_01182 1.19e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NNGKNKDC_01183 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNGKNKDC_01184 2.58e-202 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NNGKNKDC_01185 1.6e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_01186 1.19e-65 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NNGKNKDC_01187 3.81e-52 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NNGKNKDC_01189 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NNGKNKDC_01190 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNGKNKDC_01191 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NNGKNKDC_01192 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NNGKNKDC_01193 1.64e-47 yvzC - - K - - - transcriptional
NNGKNKDC_01194 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NNGKNKDC_01195 7.23e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NNGKNKDC_01196 2.97e-70 yvaP - - K - - - transcriptional
NNGKNKDC_01197 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NNGKNKDC_01198 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NNGKNKDC_01199 2.79e-176 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNGKNKDC_01200 1.91e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNGKNKDC_01201 7.67e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_01202 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNGKNKDC_01203 7.98e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNGKNKDC_01204 2.39e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNGKNKDC_01205 1.17e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNGKNKDC_01206 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NNGKNKDC_01207 5.1e-140 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNGKNKDC_01208 1.09e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNGKNKDC_01209 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNGKNKDC_01210 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNGKNKDC_01211 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NNGKNKDC_01212 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NNGKNKDC_01213 4.41e-156 yvbI - - M - - - Membrane
NNGKNKDC_01214 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NNGKNKDC_01215 1.29e-105 yvbK - - K - - - acetyltransferase
NNGKNKDC_01216 1.62e-271 - - - EGP - - - Major facilitator Superfamily
NNGKNKDC_01217 1.14e-227 - - - - - - - -
NNGKNKDC_01218 1.29e-161 - - - S - - - GlcNAc-PI de-N-acetylase
NNGKNKDC_01219 1.18e-184 - - - C - - - WbqC-like protein family
NNGKNKDC_01220 1.2e-186 - - - M - - - Protein involved in cellulose biosynthesis
NNGKNKDC_01221 1.89e-294 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NNGKNKDC_01222 4.96e-219 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
NNGKNKDC_01223 1.97e-277 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NNGKNKDC_01224 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNGKNKDC_01225 1.15e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NNGKNKDC_01226 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNGKNKDC_01227 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NNGKNKDC_01228 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNGKNKDC_01229 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NNGKNKDC_01230 8.12e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNGKNKDC_01231 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNGKNKDC_01233 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNGKNKDC_01234 6.4e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NNGKNKDC_01235 2.17e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_01237 1.24e-199 yvbU - - K - - - Transcriptional regulator
NNGKNKDC_01238 1.5e-202 yvbV - - EG - - - EamA-like transporter family
NNGKNKDC_01239 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_01240 0.0 - - - - - - - -
NNGKNKDC_01241 5.04e-231 yhjM - - K - - - Transcriptional regulator
NNGKNKDC_01242 3e-147 - - - S ko:K07149 - ko00000 Membrane
NNGKNKDC_01243 6.26e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NNGKNKDC_01244 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
NNGKNKDC_01245 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NNGKNKDC_01246 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NNGKNKDC_01247 3.39e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNGKNKDC_01248 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NNGKNKDC_01249 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNGKNKDC_01250 1.77e-281 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNGKNKDC_01251 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NNGKNKDC_01252 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NNGKNKDC_01253 4.13e-312 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NNGKNKDC_01254 4.01e-44 yvfG - - S - - - YvfG protein
NNGKNKDC_01255 6.16e-235 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NNGKNKDC_01256 5.26e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NNGKNKDC_01257 1.26e-75 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NNGKNKDC_01258 4.53e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNGKNKDC_01259 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_01260 8.95e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNGKNKDC_01261 2.6e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NNGKNKDC_01262 9.28e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NNGKNKDC_01263 1.71e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NNGKNKDC_01264 6.06e-273 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NNGKNKDC_01265 3.89e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNGKNKDC_01266 2.49e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NNGKNKDC_01267 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNGKNKDC_01268 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NNGKNKDC_01269 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NNGKNKDC_01270 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NNGKNKDC_01271 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NNGKNKDC_01273 6.92e-128 ywjB - - H - - - RibD C-terminal domain
NNGKNKDC_01274 2.51e-144 yyaS - - S ko:K07149 - ko00000 Membrane
NNGKNKDC_01275 5.46e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKNKDC_01276 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NNGKNKDC_01277 2.86e-18 - - - S - - - Protein of unknown function (DUF1433)
NNGKNKDC_01278 8.52e-51 - - - S - - - Protein of unknown function (DUF1433)
NNGKNKDC_01279 3.42e-48 - - - I - - - Pfam Lipase (class 3)
NNGKNKDC_01280 7.28e-35 - - - S - - - Protein of unknown function (DUF1433)
NNGKNKDC_01281 6.48e-27 - - - S - - - Protein of unknown function (DUF1433)
NNGKNKDC_01282 2.07e-300 - - - I - - - Pfam Lipase (class 3)
NNGKNKDC_01283 1.94e-47 - - - - - - - -
NNGKNKDC_01285 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNGKNKDC_01286 8.17e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NNGKNKDC_01287 6.67e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NNGKNKDC_01288 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNGKNKDC_01289 3.34e-210 yraN - - K - - - Transcriptional regulator
NNGKNKDC_01290 1.81e-273 yraM - - S - - - PrpF protein
NNGKNKDC_01291 0.0 - - - EGP - - - Sugar (and other) transporter
NNGKNKDC_01292 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NNGKNKDC_01293 5.31e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NNGKNKDC_01294 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NNGKNKDC_01295 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NNGKNKDC_01296 2.51e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKNKDC_01297 2.26e-104 - - - M - - - Ribonuclease
NNGKNKDC_01298 8.09e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NNGKNKDC_01299 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NNGKNKDC_01300 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NNGKNKDC_01301 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NNGKNKDC_01302 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NNGKNKDC_01303 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NNGKNKDC_01304 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNGKNKDC_01305 1.07e-203 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NNGKNKDC_01306 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NNGKNKDC_01307 1.59e-244 sasA - - T - - - Histidine kinase
NNGKNKDC_01308 5.43e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_01309 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NNGKNKDC_01310 1.99e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NNGKNKDC_01311 3.4e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NNGKNKDC_01312 5.61e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NNGKNKDC_01313 4e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NNGKNKDC_01314 1.94e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NNGKNKDC_01315 6.4e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NNGKNKDC_01316 2.14e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NNGKNKDC_01317 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NNGKNKDC_01318 5.06e-178 yvpB - - NU - - - protein conserved in bacteria
NNGKNKDC_01319 1.02e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NNGKNKDC_01320 1.35e-156 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NNGKNKDC_01321 4.33e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNGKNKDC_01322 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNGKNKDC_01323 9.55e-286 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNGKNKDC_01324 2.59e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNGKNKDC_01325 1.75e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NNGKNKDC_01326 1.8e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NNGKNKDC_01327 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NNGKNKDC_01328 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NNGKNKDC_01329 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNGKNKDC_01330 5.54e-219 yvlB - - S - - - Putative adhesin
NNGKNKDC_01331 4.01e-65 yvlA - - - - - - -
NNGKNKDC_01332 2.09e-50 yvkN - - - - - - -
NNGKNKDC_01333 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNGKNKDC_01334 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNGKNKDC_01335 2.59e-45 csbA - - S - - - protein conserved in bacteria
NNGKNKDC_01336 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NNGKNKDC_01337 2.32e-144 yvkB - - K - - - Transcriptional regulator
NNGKNKDC_01338 1.45e-298 yvkA - - P - - - -transporter
NNGKNKDC_01339 1.75e-33 - - - Q - - - Thioesterase domain
NNGKNKDC_01341 3.59e-242 - - - S - - - Psort location CytoplasmicMembrane, score
NNGKNKDC_01342 4.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNGKNKDC_01343 2.47e-73 swrA - - S - - - Swarming motility protein
NNGKNKDC_01344 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NNGKNKDC_01345 4.71e-302 ywoF - - P - - - Right handed beta helix region
NNGKNKDC_01346 5e-67 - - - L - - - transposase activity
NNGKNKDC_01347 2.34e-58 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NNGKNKDC_01348 1.01e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NNGKNKDC_01349 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NNGKNKDC_01350 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NNGKNKDC_01351 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_01352 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNGKNKDC_01353 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNGKNKDC_01354 7.96e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNGKNKDC_01355 1.35e-89 - - - - - - - -
NNGKNKDC_01356 1e-10 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NNGKNKDC_01357 1.66e-87 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NNGKNKDC_01358 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NNGKNKDC_01359 1.89e-170 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NNGKNKDC_01360 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NNGKNKDC_01361 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NNGKNKDC_01362 2.8e-108 yviE - - - - - - -
NNGKNKDC_01363 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NNGKNKDC_01364 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NNGKNKDC_01365 3.64e-104 yvyG - - NOU - - - FlgN protein
NNGKNKDC_01366 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NNGKNKDC_01367 5.47e-98 yvyF - - S - - - flagellar protein
NNGKNKDC_01368 2.48e-100 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NNGKNKDC_01369 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NNGKNKDC_01370 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NNGKNKDC_01371 8.81e-204 degV - - S - - - protein conserved in bacteria
NNGKNKDC_01372 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_01373 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NNGKNKDC_01374 1.2e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NNGKNKDC_01375 1.5e-239 yvhJ - - K - - - Transcriptional regulator
NNGKNKDC_01376 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NNGKNKDC_01377 9.43e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NNGKNKDC_01378 1.63e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NNGKNKDC_01379 1.22e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NNGKNKDC_01380 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NNGKNKDC_01381 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNGKNKDC_01382 1.46e-281 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NNGKNKDC_01383 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_01384 1.72e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNGKNKDC_01385 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNGKNKDC_01386 0.0 lytB - - D - - - Stage II sporulation protein
NNGKNKDC_01387 4.57e-65 - - - - - - - -
NNGKNKDC_01388 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NNGKNKDC_01389 7.65e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNGKNKDC_01390 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNGKNKDC_01391 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNGKNKDC_01392 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NNGKNKDC_01393 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNGKNKDC_01394 0.0 - - - M - - - Glycosyltransferase like family 2
NNGKNKDC_01395 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NNGKNKDC_01396 3.69e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNGKNKDC_01397 1.06e-278 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNGKNKDC_01398 2.88e-314 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNGKNKDC_01399 5.51e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNGKNKDC_01400 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NNGKNKDC_01401 1.09e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NNGKNKDC_01402 6.05e-272 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NNGKNKDC_01403 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
NNGKNKDC_01404 9.89e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNGKNKDC_01405 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
NNGKNKDC_01406 7.2e-200 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NNGKNKDC_01407 9.04e-77 yttA - - S - - - Pfam Transposase IS66
NNGKNKDC_01408 4.53e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNGKNKDC_01409 6.73e-28 ywtC - - - - - - -
NNGKNKDC_01410 6.62e-279 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NNGKNKDC_01411 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NNGKNKDC_01412 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NNGKNKDC_01413 2.85e-252 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NNGKNKDC_01414 3.1e-247 - - - E - - - Spore germination protein
NNGKNKDC_01415 5.9e-259 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NNGKNKDC_01416 4.99e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NNGKNKDC_01417 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNGKNKDC_01418 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NNGKNKDC_01419 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NNGKNKDC_01420 1.54e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNGKNKDC_01421 4.01e-207 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NNGKNKDC_01422 1.44e-116 batE - - T - - - Sh3 type 3 domain protein
NNGKNKDC_01423 2.06e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NNGKNKDC_01424 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NNGKNKDC_01425 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NNGKNKDC_01426 5.35e-215 alsR - - K - - - LysR substrate binding domain
NNGKNKDC_01427 3.64e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNGKNKDC_01428 3.43e-163 ywrJ - - - - - - -
NNGKNKDC_01429 1.84e-187 cotB - - - ko:K06325 - ko00000 -
NNGKNKDC_01430 2.76e-271 cotH - - M ko:K06330 - ko00000 Spore Coat
NNGKNKDC_01431 1.97e-23 - - - - - - - -
NNGKNKDC_01432 8.12e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NNGKNKDC_01434 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NNGKNKDC_01435 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NNGKNKDC_01436 1.41e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NNGKNKDC_01437 2.47e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NNGKNKDC_01438 4.32e-173 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NNGKNKDC_01439 1.78e-121 - - - - - - - -
NNGKNKDC_01440 5.04e-83 - - - - - - - -
NNGKNKDC_01441 0.0 ywqJ - - S - - - Pre-toxin TG
NNGKNKDC_01442 2.44e-49 ywqI - - S - - - Family of unknown function (DUF5344)
NNGKNKDC_01445 2.07e-192 ywqG - - S - - - Domain of unknown function (DUF1963)
NNGKNKDC_01446 1.02e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNGKNKDC_01447 2.91e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NNGKNKDC_01448 7.39e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NNGKNKDC_01449 3.37e-150 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NNGKNKDC_01450 1.74e-21 - - - - - - - -
NNGKNKDC_01451 0.0 ywqB - - S - - - SWIM zinc finger
NNGKNKDC_01452 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNGKNKDC_01453 1.84e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NNGKNKDC_01454 3.73e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNGKNKDC_01455 1.79e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NNGKNKDC_01456 4.49e-82 ywpG - - - - - - -
NNGKNKDC_01457 9.16e-91 ywpF - - S - - - YwpF-like protein
NNGKNKDC_01458 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNGKNKDC_01459 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNGKNKDC_01460 1.82e-255 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NNGKNKDC_01461 8.61e-184 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NNGKNKDC_01462 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NNGKNKDC_01463 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NNGKNKDC_01464 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NNGKNKDC_01465 3.58e-93 ywoH - - K - - - transcriptional
NNGKNKDC_01466 3.36e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_01467 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NNGKNKDC_01468 4.65e-311 ywoD - - EGP - - - Major facilitator superfamily
NNGKNKDC_01469 6.54e-132 yjgF - - Q - - - Isochorismatase family
NNGKNKDC_01470 7.64e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NNGKNKDC_01471 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NNGKNKDC_01472 2.97e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNGKNKDC_01473 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NNGKNKDC_01474 1.9e-94 ywnJ - - S - - - VanZ like family
NNGKNKDC_01475 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NNGKNKDC_01476 1.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NNGKNKDC_01478 6.01e-89 ywnF - - S - - - Family of unknown function (DUF5392)
NNGKNKDC_01479 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNGKNKDC_01480 8.03e-79 ywnC - - S - - - Family of unknown function (DUF5362)
NNGKNKDC_01481 3.58e-155 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NNGKNKDC_01482 1.08e-88 ywnA - - K - - - Transcriptional regulator
NNGKNKDC_01483 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NNGKNKDC_01484 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NNGKNKDC_01485 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NNGKNKDC_01486 2.01e-16 csbD - - K - - - CsbD-like
NNGKNKDC_01487 1.49e-107 ywmF - - S - - - Peptidase M50
NNGKNKDC_01488 1.36e-117 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NNGKNKDC_01489 1.26e-244 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NNGKNKDC_01490 1.83e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NNGKNKDC_01492 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNGKNKDC_01493 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNGKNKDC_01494 4.93e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NNGKNKDC_01495 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNGKNKDC_01496 9.75e-174 ywmB - - S - - - TATA-box binding
NNGKNKDC_01497 2.25e-45 ywzB - - S - - - membrane
NNGKNKDC_01498 4.15e-117 ywmA - - - - - - -
NNGKNKDC_01499 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NNGKNKDC_01500 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNGKNKDC_01501 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNGKNKDC_01502 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNGKNKDC_01503 1.13e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNGKNKDC_01504 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNGKNKDC_01505 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNGKNKDC_01506 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NNGKNKDC_01507 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NNGKNKDC_01508 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNGKNKDC_01509 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNGKNKDC_01510 8.67e-124 ywlG - - S - - - Belongs to the UPF0340 family
NNGKNKDC_01511 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NNGKNKDC_01512 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNGKNKDC_01513 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
NNGKNKDC_01514 6.22e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNGKNKDC_01515 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NNGKNKDC_01516 6.57e-153 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NNGKNKDC_01517 1.71e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NNGKNKDC_01519 1.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNGKNKDC_01520 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNGKNKDC_01521 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_01522 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NNGKNKDC_01523 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NNGKNKDC_01524 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NNGKNKDC_01525 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NNGKNKDC_01526 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NNGKNKDC_01527 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNGKNKDC_01528 8.27e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NNGKNKDC_01529 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNGKNKDC_01530 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NNGKNKDC_01531 2.24e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NNGKNKDC_01532 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NNGKNKDC_01533 5.49e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
NNGKNKDC_01534 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNGKNKDC_01535 1.78e-77 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNGKNKDC_01536 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NNGKNKDC_01537 2.97e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NNGKNKDC_01538 2.49e-229 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NNGKNKDC_01539 1.13e-58 ywjC - - - - - - -
NNGKNKDC_01540 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNGKNKDC_01541 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNGKNKDC_01542 1.23e-135 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNGKNKDC_01543 8.39e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NNGKNKDC_01544 4.61e-126 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NNGKNKDC_01545 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NNGKNKDC_01546 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNGKNKDC_01547 2.49e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NNGKNKDC_01548 7.49e-179 ywiC - - S - - - YwiC-like protein
NNGKNKDC_01549 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NNGKNKDC_01550 8.62e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NNGKNKDC_01551 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NNGKNKDC_01552 2.21e-94 ywiB - - S - - - protein conserved in bacteria
NNGKNKDC_01554 1.43e-307 ywhL - - CO - - - amine dehydrogenase activity
NNGKNKDC_01555 9.02e-296 ywhK - - CO - - - amine dehydrogenase activity
NNGKNKDC_01556 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNGKNKDC_01558 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NNGKNKDC_01559 2.41e-45 - - - - - - - -
NNGKNKDC_01560 9.69e-38 - - - S - - - Domain of unknown function (DUF4177)
NNGKNKDC_01562 1.15e-98 - - - CP - - - Membrane
NNGKNKDC_01565 2.45e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NNGKNKDC_01566 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NNGKNKDC_01567 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNGKNKDC_01568 1.96e-102 - - - - - - - -
NNGKNKDC_01569 3.32e-124 ywhD - - S - - - YwhD family
NNGKNKDC_01570 3.84e-153 ywhC - - S - - - Peptidase family M50
NNGKNKDC_01571 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NNGKNKDC_01572 4.16e-93 ywhA - - K - - - Transcriptional regulator
NNGKNKDC_01573 4.68e-314 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
NNGKNKDC_01574 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
NNGKNKDC_01575 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NNGKNKDC_01576 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NNGKNKDC_01577 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NNGKNKDC_01578 4.58e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
NNGKNKDC_01579 1.54e-119 - - - S - - - membrane
NNGKNKDC_01580 6.7e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_01581 1.03e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
NNGKNKDC_01584 1.25e-223 - - - - - - - -
NNGKNKDC_01586 3.72e-203 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NNGKNKDC_01587 1.22e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_01588 2.4e-213 - - - S - - - Conserved hypothetical protein 698
NNGKNKDC_01589 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NNGKNKDC_01590 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NNGKNKDC_01591 4.87e-180 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_01592 3.82e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NNGKNKDC_01593 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NNGKNKDC_01594 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NNGKNKDC_01595 1.62e-180 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_01596 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NNGKNKDC_01597 4.68e-145 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NNGKNKDC_01598 1.93e-284 ywfA - - EGP - - - -transporter
NNGKNKDC_01599 5.71e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NNGKNKDC_01600 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNGKNKDC_01601 0.0 rocB - - E - - - arginine degradation protein
NNGKNKDC_01602 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNGKNKDC_01603 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNGKNKDC_01604 2.77e-201 - - - T - - - Histidine kinase
NNGKNKDC_01605 1.5e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_01606 5.85e-97 - - - - - - - -
NNGKNKDC_01607 9.54e-150 - - - S - - - ABC-2 family transporter protein
NNGKNKDC_01608 2.28e-222 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_01609 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NNGKNKDC_01610 3.2e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNGKNKDC_01611 7.47e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNGKNKDC_01612 3.99e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNGKNKDC_01613 7.2e-236 spsG - - M - - - Spore Coat
NNGKNKDC_01614 3.53e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
NNGKNKDC_01615 1.74e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NNGKNKDC_01616 2.24e-204 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NNGKNKDC_01617 5.07e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NNGKNKDC_01618 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NNGKNKDC_01619 1.06e-182 spsA - - M - - - Spore Coat
NNGKNKDC_01620 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NNGKNKDC_01621 2.17e-76 ywdK - - S - - - small membrane protein
NNGKNKDC_01622 1.13e-292 ywdJ - - F - - - Xanthine uracil
NNGKNKDC_01623 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
NNGKNKDC_01624 5.93e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNGKNKDC_01625 2.42e-194 ywdF - - S - - - Glycosyltransferase like family 2
NNGKNKDC_01627 2.85e-115 ywdD - - - - - - -
NNGKNKDC_01628 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NNGKNKDC_01629 2.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNGKNKDC_01630 3.52e-26 ywdA - - - - - - -
NNGKNKDC_01631 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNGKNKDC_01632 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_01634 5.46e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NNGKNKDC_01636 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNGKNKDC_01637 4.69e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_01638 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NNGKNKDC_01639 1.54e-270 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NNGKNKDC_01640 2.6e-101 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NNGKNKDC_01641 8.51e-50 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NNGKNKDC_01642 6.76e-84 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NNGKNKDC_01643 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NNGKNKDC_01644 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNGKNKDC_01645 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NNGKNKDC_01646 5.74e-48 ydaS - - S - - - membrane
NNGKNKDC_01647 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NNGKNKDC_01648 1.87e-199 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNGKNKDC_01649 2e-80 gtcA - - S - - - GtrA-like protein
NNGKNKDC_01650 1.3e-145 - - - K - - - Bacterial regulatory proteins, tetR family
NNGKNKDC_01652 3.57e-166 - - - H - - - Methionine biosynthesis protein MetW
NNGKNKDC_01653 2.72e-169 - - - S - - - Streptomycin biosynthesis protein StrF
NNGKNKDC_01654 1.79e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NNGKNKDC_01655 2.66e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NNGKNKDC_01656 4.76e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NNGKNKDC_01657 3.06e-174 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NNGKNKDC_01658 4.83e-202 ywbI - - K - - - Transcriptional regulator
NNGKNKDC_01659 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NNGKNKDC_01660 1.86e-143 ywbG - - M - - - effector of murein hydrolase
NNGKNKDC_01661 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NNGKNKDC_01662 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNGKNKDC_01663 2.74e-314 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNGKNKDC_01666 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_01667 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNGKNKDC_01668 2.36e-40 - - - S - - - GlpM protein
NNGKNKDC_01669 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NNGKNKDC_01670 3.05e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NNGKNKDC_01671 1.18e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNGKNKDC_01672 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNGKNKDC_01673 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNGKNKDC_01674 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNGKNKDC_01675 1.85e-34 yqzJ - - - - - - -
NNGKNKDC_01676 5.86e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNGKNKDC_01677 3.04e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NNGKNKDC_01678 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNGKNKDC_01679 4.64e-96 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NNGKNKDC_01681 1.57e-124 yqjB - - S - - - protein conserved in bacteria
NNGKNKDC_01682 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NNGKNKDC_01683 3.01e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNGKNKDC_01684 2.55e-112 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNGKNKDC_01685 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNGKNKDC_01686 4.62e-107 yfiV - - K - - - transcriptional
NNGKNKDC_01687 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNGKNKDC_01688 1.86e-211 yfhB - - S - - - PhzF family
NNGKNKDC_01689 1.36e-136 yfhC - - C - - - nitroreductase
NNGKNKDC_01690 3.61e-34 yfhD - - S - - - YfhD-like protein
NNGKNKDC_01692 1.03e-15 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NNGKNKDC_01693 6.12e-173 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NNGKNKDC_01694 3.14e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NNGKNKDC_01695 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
NNGKNKDC_01696 2.86e-268 yfhI - - EGP - - - -transporter
NNGKNKDC_01698 6.74e-214 mpr - - M - - - Belongs to the peptidase S1B family
NNGKNKDC_01699 2.57e-59 yfhJ - - S - - - WVELL protein
NNGKNKDC_01700 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
NNGKNKDC_01701 4.24e-57 yfhL - - S - - - SdpI/YhfL protein family
NNGKNKDC_01702 9.27e-217 - - - S - - - Alpha/beta hydrolase family
NNGKNKDC_01703 1.57e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNGKNKDC_01704 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NNGKNKDC_01705 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NNGKNKDC_01706 2.63e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NNGKNKDC_01707 2.54e-50 yfhS - - - - - - -
NNGKNKDC_01708 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_01709 7.33e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NNGKNKDC_01710 1.4e-49 ygaB - - S - - - YgaB-like protein
NNGKNKDC_01711 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NNGKNKDC_01712 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NNGKNKDC_01713 5.27e-239 ygaE - - S - - - Membrane
NNGKNKDC_01714 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NNGKNKDC_01715 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NNGKNKDC_01716 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NNGKNKDC_01717 4.67e-75 ygzB - - S - - - UPF0295 protein
NNGKNKDC_01718 1.86e-211 ygxA - - S - - - Nucleotidyltransferase-like
NNGKNKDC_01721 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNGKNKDC_01722 5.71e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NNGKNKDC_01723 2.41e-111 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NNGKNKDC_01724 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
NNGKNKDC_01725 0.0 ybeC - - E - - - amino acid
NNGKNKDC_01726 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
NNGKNKDC_01727 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNGKNKDC_01728 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NNGKNKDC_01729 9.7e-274 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NNGKNKDC_01730 1.88e-153 - - - K ko:K05799 - ko00000,ko03000 FCD
NNGKNKDC_01731 3.41e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NNGKNKDC_01732 3.18e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NNGKNKDC_01733 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
NNGKNKDC_01735 0.0 pbpE - - V - - - Beta-lactamase
NNGKNKDC_01738 1.12e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNGKNKDC_01739 2.29e-154 ydhC - - K - - - FCD
NNGKNKDC_01740 1.91e-27 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NNGKNKDC_01743 8.41e-91 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NNGKNKDC_01744 1.63e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
NNGKNKDC_01745 2.25e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NNGKNKDC_01746 4.43e-192 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNGKNKDC_01747 3.98e-191 bltR - - K - - - helix_turn_helix, mercury resistance
NNGKNKDC_01748 1.25e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NNGKNKDC_01749 2.58e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NNGKNKDC_01750 1.3e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
NNGKNKDC_01751 2.76e-288 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNGKNKDC_01752 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_01753 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_01754 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_01755 4.83e-99 yqiW - - S - - - Belongs to the UPF0403 family
NNGKNKDC_01756 2.02e-217 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNGKNKDC_01757 1.78e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNGKNKDC_01758 9.83e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNGKNKDC_01759 1.59e-221 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNGKNKDC_01760 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNGKNKDC_01761 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NNGKNKDC_01762 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNGKNKDC_01763 2.37e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NNGKNKDC_01764 0.0 bkdR - - KT - - - Transcriptional regulator
NNGKNKDC_01765 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
NNGKNKDC_01766 3.29e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NNGKNKDC_01767 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NNGKNKDC_01768 2.07e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNGKNKDC_01769 4.53e-263 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NNGKNKDC_01770 2.41e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NNGKNKDC_01771 1.87e-270 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NNGKNKDC_01772 1.56e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NNGKNKDC_01773 6.87e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NNGKNKDC_01775 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
NNGKNKDC_01776 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
NNGKNKDC_01777 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NNGKNKDC_01778 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
NNGKNKDC_01779 1.72e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNGKNKDC_01780 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNGKNKDC_01781 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNGKNKDC_01782 5e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNGKNKDC_01783 1.75e-129 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NNGKNKDC_01784 8.68e-279 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NNGKNKDC_01785 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NNGKNKDC_01786 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NNGKNKDC_01788 1.46e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NNGKNKDC_01789 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNGKNKDC_01790 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NNGKNKDC_01791 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NNGKNKDC_01792 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNGKNKDC_01793 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NNGKNKDC_01794 2.02e-234 yaaC - - S - - - YaaC-like Protein
NNGKNKDC_01795 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NNGKNKDC_01796 1.28e-71 - - - L - - - COG2963 Transposase and inactivated derivatives
NNGKNKDC_01797 3.71e-140 ymaB - - S - - - MutT family
NNGKNKDC_01798 2.35e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNGKNKDC_01799 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNGKNKDC_01800 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NNGKNKDC_01801 9.42e-29 ymzA - - - - - - -
NNGKNKDC_01802 1.47e-59 - - - - - - - -
NNGKNKDC_01803 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NNGKNKDC_01804 8.91e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNGKNKDC_01805 5.96e-77 ymaF - - S - - - YmaF family
NNGKNKDC_01807 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNGKNKDC_01808 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNGKNKDC_01809 1.41e-103 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NNGKNKDC_01810 1.14e-162 ymaC - - S - - - Replication protein
NNGKNKDC_01811 3.46e-05 - - - - - - - -
NNGKNKDC_01812 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NNGKNKDC_01813 2.78e-82 ymzB - - - - - - -
NNGKNKDC_01814 2.21e-153 yoaK - - S - - - Membrane
NNGKNKDC_01815 1.01e-100 nucB - - M - - - Deoxyribonuclease NucA/NucB
NNGKNKDC_01816 1.68e-294 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNGKNKDC_01817 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NNGKNKDC_01818 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NNGKNKDC_01819 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_01820 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_01821 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NNGKNKDC_01822 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NNGKNKDC_01823 1.06e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NNGKNKDC_01824 5.38e-311 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NNGKNKDC_01825 4.34e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NNGKNKDC_01826 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_01827 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NNGKNKDC_01828 7.83e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_01829 1.65e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NNGKNKDC_01831 3.97e-49 - - - - - - - -
NNGKNKDC_01832 5.54e-51 - - - L - - - Belongs to the 'phage' integrase family
NNGKNKDC_01833 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNGKNKDC_01834 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNGKNKDC_01835 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NNGKNKDC_01836 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NNGKNKDC_01837 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NNGKNKDC_01838 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNGKNKDC_01839 8.3e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NNGKNKDC_01840 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NNGKNKDC_01841 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NNGKNKDC_01842 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NNGKNKDC_01843 7.43e-277 pbpX - - V - - - Beta-lactamase
NNGKNKDC_01844 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNGKNKDC_01845 8.03e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NNGKNKDC_01846 9.58e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNGKNKDC_01847 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NNGKNKDC_01848 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
NNGKNKDC_01849 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
NNGKNKDC_01850 2.47e-165 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NNGKNKDC_01851 3.23e-307 ymfH - - S - - - zinc protease
NNGKNKDC_01852 6.23e-304 albE - - S - - - Peptidase M16
NNGKNKDC_01853 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NNGKNKDC_01854 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_01855 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_01856 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_01857 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNGKNKDC_01858 6.32e-42 - - - S - - - YlzJ-like protein
NNGKNKDC_01859 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NNGKNKDC_01860 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNGKNKDC_01861 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNGKNKDC_01862 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNGKNKDC_01863 3.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNGKNKDC_01864 3.9e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NNGKNKDC_01865 1.35e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NNGKNKDC_01866 2.17e-56 ymxH - - S - - - YlmC YmxH family
NNGKNKDC_01867 5.91e-299 mlpA - - S - - - Belongs to the peptidase M16 family
NNGKNKDC_01868 1.02e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NNGKNKDC_01869 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NNGKNKDC_01870 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNGKNKDC_01871 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NNGKNKDC_01872 2.02e-218 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNGKNKDC_01873 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNGKNKDC_01874 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NNGKNKDC_01875 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNGKNKDC_01876 1.24e-62 ylxQ - - J - - - ribosomal protein
NNGKNKDC_01877 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NNGKNKDC_01878 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NNGKNKDC_01879 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NNGKNKDC_01880 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNGKNKDC_01881 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNGKNKDC_01882 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NNGKNKDC_01883 8.96e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NNGKNKDC_01884 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NNGKNKDC_01885 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNGKNKDC_01886 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNGKNKDC_01887 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NNGKNKDC_01888 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNGKNKDC_01889 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NNGKNKDC_01890 8.31e-94 ylxL - - - - - - -
NNGKNKDC_01891 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_01892 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NNGKNKDC_01893 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NNGKNKDC_01894 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NNGKNKDC_01895 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NNGKNKDC_01896 8.24e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NNGKNKDC_01897 1.28e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NNGKNKDC_01898 7.94e-250 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NNGKNKDC_01899 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNGKNKDC_01900 3.59e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNGKNKDC_01901 2.33e-167 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NNGKNKDC_01902 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NNGKNKDC_01903 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NNGKNKDC_01904 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NNGKNKDC_01905 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NNGKNKDC_01906 1.71e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NNGKNKDC_01907 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNGKNKDC_01908 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NNGKNKDC_01909 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NNGKNKDC_01910 1.54e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NNGKNKDC_01911 2.11e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NNGKNKDC_01912 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
NNGKNKDC_01913 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NNGKNKDC_01914 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NNGKNKDC_01915 2.29e-121 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NNGKNKDC_01916 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNGKNKDC_01917 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NNGKNKDC_01918 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NNGKNKDC_01919 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NNGKNKDC_01920 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NNGKNKDC_01921 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NNGKNKDC_01922 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNGKNKDC_01923 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNGKNKDC_01924 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NNGKNKDC_01925 3.15e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNGKNKDC_01926 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNGKNKDC_01927 1.42e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NNGKNKDC_01928 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NNGKNKDC_01929 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NNGKNKDC_01930 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NNGKNKDC_01931 0.0 ylqG - - - - - - -
NNGKNKDC_01932 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNGKNKDC_01933 8.45e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNGKNKDC_01934 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNGKNKDC_01935 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NNGKNKDC_01936 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNGKNKDC_01937 3.41e-80 ylqD - - S - - - YlqD protein
NNGKNKDC_01938 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NNGKNKDC_01939 4.59e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NNGKNKDC_01940 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNGKNKDC_01941 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNGKNKDC_01942 1.06e-182 - - - S - - - Phosphotransferase enzyme family
NNGKNKDC_01943 6.26e-223 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNGKNKDC_01944 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NNGKNKDC_01945 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNGKNKDC_01946 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNGKNKDC_01947 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNGKNKDC_01948 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_01949 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNGKNKDC_01950 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NNGKNKDC_01951 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNGKNKDC_01952 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NNGKNKDC_01953 3.41e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NNGKNKDC_01954 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NNGKNKDC_01955 3.65e-78 yloU - - S - - - protein conserved in bacteria
NNGKNKDC_01956 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NNGKNKDC_01957 2.24e-154 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NNGKNKDC_01958 6.15e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NNGKNKDC_01959 7.27e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNGKNKDC_01960 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNGKNKDC_01961 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NNGKNKDC_01962 2.52e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NNGKNKDC_01963 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNGKNKDC_01964 7.89e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNGKNKDC_01965 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNGKNKDC_01966 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNGKNKDC_01967 8.87e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNGKNKDC_01968 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNGKNKDC_01969 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NNGKNKDC_01970 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NNGKNKDC_01971 2.5e-197 yloC - - S - - - stress-induced protein
NNGKNKDC_01972 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NNGKNKDC_01973 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NNGKNKDC_01974 3.63e-105 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NNGKNKDC_01975 7.18e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NNGKNKDC_01976 2.4e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NNGKNKDC_01977 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NNGKNKDC_01978 8.77e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NNGKNKDC_01979 4.93e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NNGKNKDC_01980 1.99e-180 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NNGKNKDC_01982 2.2e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNGKNKDC_01983 4.99e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNGKNKDC_01984 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNGKNKDC_01985 1.5e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NNGKNKDC_01986 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NNGKNKDC_01987 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNGKNKDC_01988 1.74e-311 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNGKNKDC_01989 4.21e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NNGKNKDC_01990 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NNGKNKDC_01991 6.32e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNGKNKDC_01992 1.08e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNGKNKDC_01993 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNGKNKDC_01994 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NNGKNKDC_01995 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNGKNKDC_01996 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NNGKNKDC_01997 5.03e-181 ylmH - - S - - - conserved protein, contains S4-like domain
NNGKNKDC_01998 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NNGKNKDC_01999 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNGKNKDC_02000 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NNGKNKDC_02001 7.85e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NNGKNKDC_02002 7.13e-52 ylmC - - S - - - sporulation protein
NNGKNKDC_02003 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NNGKNKDC_02004 1.62e-186 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NNGKNKDC_02005 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_02006 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_02007 4.76e-217 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NNGKNKDC_02008 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NNGKNKDC_02009 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNGKNKDC_02010 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNGKNKDC_02011 1.09e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNGKNKDC_02012 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NNGKNKDC_02013 5.45e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNGKNKDC_02014 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNGKNKDC_02015 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNGKNKDC_02016 1.42e-221 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNGKNKDC_02017 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNGKNKDC_02018 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NNGKNKDC_02019 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNGKNKDC_02020 2.4e-68 ftsL - - D - - - Essential cell division protein
NNGKNKDC_02021 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNGKNKDC_02022 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NNGKNKDC_02023 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NNGKNKDC_02024 5.87e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNGKNKDC_02025 1.38e-117 ylbP - - K - - - n-acetyltransferase
NNGKNKDC_02026 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NNGKNKDC_02027 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NNGKNKDC_02028 7.78e-114 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NNGKNKDC_02029 2.59e-295 ylbM - - S - - - Belongs to the UPF0348 family
NNGKNKDC_02030 2.07e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NNGKNKDC_02031 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NNGKNKDC_02032 2.79e-275 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NNGKNKDC_02033 3.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNGKNKDC_02034 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NNGKNKDC_02036 3.94e-57 ylbG - - S - - - UPF0298 protein
NNGKNKDC_02037 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
NNGKNKDC_02038 1.73e-48 ylbE - - S - - - YlbE-like protein
NNGKNKDC_02039 1.03e-87 ylbD - - S - - - Putative coat protein
NNGKNKDC_02040 1.09e-252 ylbC - - S - - - protein with SCP PR1 domains
NNGKNKDC_02041 7.89e-95 ylbB - - T - - - COG0517 FOG CBS domain
NNGKNKDC_02042 4.12e-79 ylbA - - S - - - YugN-like family
NNGKNKDC_02043 3.59e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NNGKNKDC_02044 7.12e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NNGKNKDC_02045 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NNGKNKDC_02046 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNGKNKDC_02047 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NNGKNKDC_02048 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNGKNKDC_02049 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NNGKNKDC_02050 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNGKNKDC_02051 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNGKNKDC_02052 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
NNGKNKDC_02053 3.8e-223 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NNGKNKDC_02054 1.23e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NNGKNKDC_02055 9.03e-312 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NNGKNKDC_02056 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNGKNKDC_02057 6.78e-46 ylaI - - S - - - protein conserved in bacteria
NNGKNKDC_02058 6.99e-65 - - - S - - - YlaH-like protein
NNGKNKDC_02059 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NNGKNKDC_02060 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
NNGKNKDC_02061 2.83e-62 ylaE - - - - - - -
NNGKNKDC_02063 2.33e-120 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_02064 8.95e-60 ylaB - - - - - - -
NNGKNKDC_02065 4.03e-241 ylaA - - - - - - -
NNGKNKDC_02066 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NNGKNKDC_02067 1.78e-106 ykzC - - S - - - Acetyltransferase (GNAT) family
NNGKNKDC_02068 1.35e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NNGKNKDC_02069 3.33e-33 ykzI - - - - - - -
NNGKNKDC_02070 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
NNGKNKDC_02071 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
NNGKNKDC_02072 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NNGKNKDC_02073 1.29e-188 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NNGKNKDC_02074 2.39e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NNGKNKDC_02075 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNGKNKDC_02076 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNGKNKDC_02077 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNGKNKDC_02078 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNGKNKDC_02079 1.85e-264 - - - V - - - Beta-lactamase
NNGKNKDC_02080 0.0 - - - IQ - - - Phosphopantetheine attachment site
NNGKNKDC_02081 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02082 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02083 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02084 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02085 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
NNGKNKDC_02086 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02087 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_02088 1.32e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
NNGKNKDC_02090 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNGKNKDC_02091 3.17e-189 ykrA - - S - - - hydrolases of the HAD superfamily
NNGKNKDC_02092 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
NNGKNKDC_02093 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNGKNKDC_02094 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NNGKNKDC_02095 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NNGKNKDC_02096 1.69e-193 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NNGKNKDC_02097 1.68e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNGKNKDC_02098 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NNGKNKDC_02099 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NNGKNKDC_02100 4.47e-18 - - - S - - - Uncharacterized protein YkpC
NNGKNKDC_02101 9.85e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NNGKNKDC_02102 1.47e-212 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNGKNKDC_02103 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNGKNKDC_02104 1.5e-49 ykoA - - - - - - -
NNGKNKDC_02105 5.36e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNGKNKDC_02106 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NNGKNKDC_02107 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NNGKNKDC_02108 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_02109 9.96e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NNGKNKDC_02110 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_02111 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNGKNKDC_02112 1.14e-140 yknW - - S - - - Yip1 domain
NNGKNKDC_02113 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NNGKNKDC_02114 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NNGKNKDC_02115 4.56e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NNGKNKDC_02116 1.44e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NNGKNKDC_02117 2e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNGKNKDC_02118 1.36e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NNGKNKDC_02119 1.03e-217 yknT - - - ko:K06437 - ko00000 -
NNGKNKDC_02120 3.04e-126 rok - - K - - - Repressor of ComK
NNGKNKDC_02121 6.53e-90 ykuV - - CO - - - thiol-disulfide
NNGKNKDC_02122 7.03e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NNGKNKDC_02123 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
NNGKNKDC_02124 5.63e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNGKNKDC_02125 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNGKNKDC_02126 3.59e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
NNGKNKDC_02127 7.62e-217 ykuO - - - - - - -
NNGKNKDC_02128 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
NNGKNKDC_02129 1.32e-215 ccpC - - K - - - Transcriptional regulator
NNGKNKDC_02130 8.55e-99 ykuL - - S - - - CBS domain
NNGKNKDC_02131 3.09e-35 ykzF - - S - - - Antirepressor AbbA
NNGKNKDC_02132 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
NNGKNKDC_02133 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
NNGKNKDC_02134 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
NNGKNKDC_02136 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_02137 7.71e-199 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NNGKNKDC_02138 2.55e-116 ykuD - - S - - - protein conserved in bacteria
NNGKNKDC_02139 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_02140 5.07e-108 ykyB - - S - - - YkyB-like protein
NNGKNKDC_02141 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NNGKNKDC_02142 6.38e-15 - - - - - - - -
NNGKNKDC_02143 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNGKNKDC_02144 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02145 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNGKNKDC_02146 5.67e-166 ykwD - - J - - - protein with SCP PR1 domains
NNGKNKDC_02147 1.21e-65 - - - - - - - -
NNGKNKDC_02148 7.78e-201 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NNGKNKDC_02149 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNGKNKDC_02150 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NNGKNKDC_02151 1.48e-49 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_02152 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNGKNKDC_02153 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NNGKNKDC_02154 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02155 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NNGKNKDC_02156 1.01e-224 ykvZ - - K - - - Transcriptional regulator
NNGKNKDC_02158 9.5e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NNGKNKDC_02159 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NNGKNKDC_02160 8.57e-114 stoA - - CO - - - thiol-disulfide
NNGKNKDC_02161 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_02162 7.21e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NNGKNKDC_02163 7.17e-39 - - - - - - - -
NNGKNKDC_02164 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NNGKNKDC_02165 1.66e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
NNGKNKDC_02166 2.57e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_02167 2.54e-77 ykvN - - K - - - Transcriptional regulator
NNGKNKDC_02169 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NNGKNKDC_02170 1.02e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NNGKNKDC_02171 3.35e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NNGKNKDC_02172 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NNGKNKDC_02173 6.29e-252 - - - - - - - -
NNGKNKDC_02174 7.37e-230 ykvI - - S - - - membrane
NNGKNKDC_02175 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NNGKNKDC_02176 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NNGKNKDC_02177 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NNGKNKDC_02178 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NNGKNKDC_02179 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNGKNKDC_02181 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NNGKNKDC_02182 9.5e-149 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NNGKNKDC_02183 6.66e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NNGKNKDC_02184 7.83e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NNGKNKDC_02185 1.73e-289 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNGKNKDC_02186 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNGKNKDC_02187 7e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NNGKNKDC_02188 1.09e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NNGKNKDC_02190 1.04e-110 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNGKNKDC_02191 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02192 6.46e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NNGKNKDC_02193 3.07e-32 ykzE - - - - - - -
NNGKNKDC_02194 5.8e-146 - - - S - - - Protein of unknown function (DUF421)
NNGKNKDC_02195 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NNGKNKDC_02196 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NNGKNKDC_02197 1.62e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
NNGKNKDC_02198 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NNGKNKDC_02199 3.6e-250 ykrI - - S - - - Anti-sigma factor N-terminus
NNGKNKDC_02200 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_02201 3.39e-172 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NNGKNKDC_02202 1.6e-128 ykoX - - S - - - membrane-associated protein
NNGKNKDC_02203 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NNGKNKDC_02204 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NNGKNKDC_02205 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
NNGKNKDC_02206 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NNGKNKDC_02207 5.25e-37 ykoL - - - - - - -
NNGKNKDC_02208 1.11e-23 - - - - - - - -
NNGKNKDC_02209 1.23e-69 tnrA - - K - - - transcriptional
NNGKNKDC_02210 4.11e-308 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NNGKNKDC_02212 3.79e-311 ydhD - - M - - - Glycosyl hydrolase
NNGKNKDC_02213 1.33e-125 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NNGKNKDC_02214 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_02215 1.54e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NNGKNKDC_02216 6.61e-192 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNGKNKDC_02217 8.62e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNGKNKDC_02218 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NNGKNKDC_02219 6.67e-157 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NNGKNKDC_02220 1.97e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_02221 1.38e-173 - - - K - - - Collagen triple helix repeat
NNGKNKDC_02222 1.01e-274 - - - M - - - Glycosyl transferase family 2
NNGKNKDC_02224 9.03e-80 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NNGKNKDC_02225 9.16e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
NNGKNKDC_02226 3.45e-111 ohrR - - K - - - COG1846 Transcriptional regulators
NNGKNKDC_02227 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
NNGKNKDC_02228 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNGKNKDC_02229 1.25e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNGKNKDC_02230 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NNGKNKDC_02231 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NNGKNKDC_02232 2.02e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NNGKNKDC_02233 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNGKNKDC_02234 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
NNGKNKDC_02235 9.87e-203 ykgA - - E - - - Amidinotransferase
NNGKNKDC_02236 8.42e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NNGKNKDC_02237 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_02238 7.63e-218 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNGKNKDC_02239 1.1e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NNGKNKDC_02240 1.61e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NNGKNKDC_02241 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNGKNKDC_02242 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_02243 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_02244 9.77e-205 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNGKNKDC_02245 1.03e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NNGKNKDC_02247 0.0 yubD - - P - - - Major Facilitator Superfamily
NNGKNKDC_02248 2.16e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNGKNKDC_02250 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNGKNKDC_02251 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNGKNKDC_02252 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNGKNKDC_02253 1.09e-310 steT - - E ko:K03294 - ko00000 amino acid
NNGKNKDC_02254 1.2e-140 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NNGKNKDC_02255 4.98e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
NNGKNKDC_02256 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NNGKNKDC_02257 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NNGKNKDC_02258 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NNGKNKDC_02259 4.7e-52 xhlB - - S - - - SPP1 phage holin
NNGKNKDC_02260 3.87e-51 xhlA - - S - - - Haemolysin XhlA
NNGKNKDC_02261 7.72e-179 xepA - - - - - - -
NNGKNKDC_02262 3.25e-40 xkdX - - - - - - -
NNGKNKDC_02264 1.74e-109 - - - - - - - -
NNGKNKDC_02265 3.63e-37 - - - - - - - -
NNGKNKDC_02266 7.1e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NNGKNKDC_02267 1.08e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NNGKNKDC_02268 9.56e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
NNGKNKDC_02269 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
NNGKNKDC_02270 7.63e-206 xkdQ - - G - - - NLP P60 protein
NNGKNKDC_02271 6.56e-145 xkdP - - S - - - Lysin motif
NNGKNKDC_02272 9.27e-278 xkdO - - L - - - Transglycosylase SLT domain
NNGKNKDC_02273 4.33e-27 - - - - - - - -
NNGKNKDC_02274 2.09e-95 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NNGKNKDC_02275 8.21e-97 xkdM - - S - - - Phage tail tube protein
NNGKNKDC_02276 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
NNGKNKDC_02277 1.57e-20 - - - - - - - -
NNGKNKDC_02278 8.64e-74 xkdJ - - - - - - -
NNGKNKDC_02279 1.7e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNGKNKDC_02280 5.78e-56 - - - S - - - Domain of unknown function (DUF3599)
NNGKNKDC_02281 2.17e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
NNGKNKDC_02282 8.3e-203 xkdG - - S - - - Phage capsid family
NNGKNKDC_02283 1.25e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
NNGKNKDC_02284 1.48e-303 xkdE3 - - S - - - portal protein
NNGKNKDC_02285 1.36e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NNGKNKDC_02286 1.18e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NNGKNKDC_02287 2.15e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NNGKNKDC_02291 3.06e-196 xkdC - - L - - - Bacterial dnaA protein
NNGKNKDC_02293 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
NNGKNKDC_02294 2.65e-144 xkdA - - E - - - IrrE N-terminal-like domain
NNGKNKDC_02296 6.21e-141 yjqB - - S - - - phage-related replication protein
NNGKNKDC_02297 9.51e-81 yjqA - - S - - - Bacterial PH domain
NNGKNKDC_02298 4.78e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNGKNKDC_02300 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NNGKNKDC_02301 1.19e-102 yjoA - - S - - - DinB family
NNGKNKDC_02302 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NNGKNKDC_02303 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NNGKNKDC_02304 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NNGKNKDC_02305 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NNGKNKDC_02306 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
NNGKNKDC_02307 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NNGKNKDC_02308 6.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNGKNKDC_02309 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NNGKNKDC_02310 2.46e-118 yjlB - - S - - - Cupin domain
NNGKNKDC_02311 4.11e-227 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NNGKNKDC_02312 1.08e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_02313 2.42e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NNGKNKDC_02314 1.01e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NNGKNKDC_02315 2.03e-39 - - - - - - - -
NNGKNKDC_02316 3.08e-286 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNGKNKDC_02317 2.19e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNGKNKDC_02318 6.31e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
NNGKNKDC_02319 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNGKNKDC_02320 6.05e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
NNGKNKDC_02321 1.66e-87 yjgA - - T - - - Protein of unknown function (DUF2809)
NNGKNKDC_02322 1.91e-31 yjfB - - S - - - Putative motility protein
NNGKNKDC_02323 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NNGKNKDC_02326 1.62e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
NNGKNKDC_02327 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNGKNKDC_02328 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKNKDC_02329 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02330 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKNKDC_02331 3.52e-273 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNGKNKDC_02332 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNGKNKDC_02333 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NNGKNKDC_02334 1.1e-280 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NNGKNKDC_02335 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_02336 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
NNGKNKDC_02337 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NNGKNKDC_02338 8.15e-211 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NNGKNKDC_02339 3.27e-78 - - - E - - - Glyoxalase-like domain
NNGKNKDC_02342 6.59e-252 - - - M - - - nucleic acid phosphodiester bond hydrolysis
NNGKNKDC_02344 1.33e-50 - - - - - - - -
NNGKNKDC_02345 1e-29 - - - - - - - -
NNGKNKDC_02346 6.09e-70 - - - L - - - COG2963 Transposase and inactivated derivatives
NNGKNKDC_02347 3.8e-122 - - - L - - - Transposase
NNGKNKDC_02362 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NNGKNKDC_02363 1.17e-223 yplP - - K - - - Transcriptional regulator
NNGKNKDC_02364 1.42e-307 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NNGKNKDC_02365 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
NNGKNKDC_02366 9.91e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NNGKNKDC_02367 1.49e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NNGKNKDC_02368 5.59e-126 ypmS - - S - - - protein conserved in bacteria
NNGKNKDC_02369 3.35e-89 ypoP - - K - - - transcriptional
NNGKNKDC_02370 1.99e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNGKNKDC_02371 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NNGKNKDC_02372 3.43e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNGKNKDC_02373 0.0 yokA - - L - - - Recombinase
NNGKNKDC_02374 7.87e-106 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NNGKNKDC_02375 2.12e-100 yokH - - G - - - SMI1 / KNR4 family
NNGKNKDC_02376 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNGKNKDC_02377 1.29e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNGKNKDC_02380 9.52e-94 - - - S - - - amine dehydrogenase activity
NNGKNKDC_02381 2.75e-45 - - - S - - - amine dehydrogenase activity
NNGKNKDC_02383 1.04e-249 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNGKNKDC_02384 1.05e-06 - - - - - - - -
NNGKNKDC_02387 6.26e-91 yoaW - - - - - - -
NNGKNKDC_02392 9.91e-16 - - - S - - - Protein of unknown function (DUF4236)
NNGKNKDC_02393 2.43e-48 - - - K - - - Putative DNA-binding domain
NNGKNKDC_02395 1.48e-12 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NNGKNKDC_02396 5.61e-15 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNGKNKDC_02397 1.44e-266 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNGKNKDC_02398 3.08e-81 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNGKNKDC_02399 1.61e-82 - - - - - - - -
NNGKNKDC_02402 4.83e-187 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNGKNKDC_02403 2.11e-61 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNGKNKDC_02404 2.08e-96 yoqH - - M - - - LysM domain
NNGKNKDC_02405 4.17e-84 - - - S - - - Acetyltransferase (GNAT) domain
NNGKNKDC_02406 2.04e-105 - - - - - - - -
NNGKNKDC_02410 5.03e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNGKNKDC_02411 2.23e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NNGKNKDC_02412 2.59e-230 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NNGKNKDC_02413 4.26e-88 cgeA - - - ko:K06319 - ko00000 -
NNGKNKDC_02414 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NNGKNKDC_02415 4.69e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NNGKNKDC_02417 2.79e-82 - - - L - - - Bacterial transcription activator, effector binding domain
NNGKNKDC_02418 1.33e-309 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNGKNKDC_02419 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNGKNKDC_02420 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNGKNKDC_02421 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NNGKNKDC_02422 1.78e-206 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NNGKNKDC_02423 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NNGKNKDC_02424 3.32e-61 yokU - - S - - - YokU-like protein, putative antitoxin
NNGKNKDC_02425 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
NNGKNKDC_02426 1.9e-161 yodN - - - - - - -
NNGKNKDC_02428 9.77e-34 yozD - - S - - - YozD-like protein
NNGKNKDC_02429 3.55e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NNGKNKDC_02430 1.16e-72 yodL - - S - - - YodL-like
NNGKNKDC_02432 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NNGKNKDC_02433 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NNGKNKDC_02434 6.87e-50 yodI - - - - - - -
NNGKNKDC_02435 7.15e-165 yodH - - Q - - - Methyltransferase
NNGKNKDC_02436 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NNGKNKDC_02437 1.68e-167 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_02438 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKNKDC_02439 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NNGKNKDC_02440 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNGKNKDC_02441 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
NNGKNKDC_02442 1.8e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNGKNKDC_02443 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NNGKNKDC_02444 1.35e-138 yodC - - C - - - nitroreductase
NNGKNKDC_02445 1.2e-74 yodB - - K - - - transcriptional
NNGKNKDC_02446 2.64e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
NNGKNKDC_02447 1.05e-88 iolK - - S - - - tautomerase
NNGKNKDC_02449 8.08e-105 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NNGKNKDC_02450 2.96e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NNGKNKDC_02451 3.66e-31 - - - - - - - -
NNGKNKDC_02452 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
NNGKNKDC_02453 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NNGKNKDC_02454 1.18e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNGKNKDC_02455 9.74e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NNGKNKDC_02457 1.11e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNGKNKDC_02458 2.45e-287 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NNGKNKDC_02459 6.42e-283 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNGKNKDC_02460 2.65e-144 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NNGKNKDC_02461 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NNGKNKDC_02462 0.0 yojO - - P - - - Von Willebrand factor
NNGKNKDC_02463 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NNGKNKDC_02464 1.05e-262 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NNGKNKDC_02465 8.77e-183 - - - S - - - Metallo-beta-lactamase superfamily
NNGKNKDC_02466 1.34e-212 yocS - - S ko:K03453 - ko00000 -transporter
NNGKNKDC_02467 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNGKNKDC_02468 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NNGKNKDC_02469 2.54e-39 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NNGKNKDC_02470 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NNGKNKDC_02471 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNGKNKDC_02472 1.91e-42 yozC - - - - - - -
NNGKNKDC_02474 5.32e-75 yozO - - S - - - Bacterial PH domain
NNGKNKDC_02475 6.36e-50 yocN - - - - - - -
NNGKNKDC_02476 5.58e-59 yozN - - - - - - -
NNGKNKDC_02477 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNGKNKDC_02478 3.51e-13 yocN - - - - - - -
NNGKNKDC_02479 1.92e-13 yocL - - - - - - -
NNGKNKDC_02480 3.36e-74 yocK - - T - - - general stress protein
NNGKNKDC_02482 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNGKNKDC_02483 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNGKNKDC_02484 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
NNGKNKDC_02486 1.65e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NNGKNKDC_02487 2.27e-123 yocC - - - - - - -
NNGKNKDC_02488 3.38e-179 - - - J - - - Protein required for attachment to host cells
NNGKNKDC_02489 1.55e-116 yozB - - S ko:K08976 - ko00000 membrane
NNGKNKDC_02490 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNGKNKDC_02491 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NNGKNKDC_02492 3.86e-119 yobW - - - - - - -
NNGKNKDC_02493 1.1e-171 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNGKNKDC_02494 4.57e-123 yobS - - K - - - Transcriptional regulator
NNGKNKDC_02495 1.06e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NNGKNKDC_02496 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NNGKNKDC_02497 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNGKNKDC_02498 1.88e-71 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNGKNKDC_02499 3.23e-59 - - - - - - - -
NNGKNKDC_02500 2.31e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_02502 4.24e-34 yoaF - - - - - - -
NNGKNKDC_02503 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNGKNKDC_02504 1.36e-242 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKNKDC_02505 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NNGKNKDC_02506 1.28e-260 yoaB - - EGP - - - the major facilitator superfamily
NNGKNKDC_02507 2.69e-179 yoxB - - - - - - -
NNGKNKDC_02508 2.6e-51 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNGKNKDC_02509 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_02510 3.88e-283 - - - K - - - helix_turn_helix, arabinose operon control protein
NNGKNKDC_02511 2.49e-181 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_02512 3.4e-98 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNGKNKDC_02513 3.37e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NNGKNKDC_02514 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNGKNKDC_02515 1.7e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNGKNKDC_02516 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_02517 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NNGKNKDC_02518 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NNGKNKDC_02519 1.77e-239 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NNGKNKDC_02520 1.57e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_02521 1.49e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNGKNKDC_02522 3.29e-67 - - - K - - - Helix-turn-helix domain
NNGKNKDC_02523 4.59e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
NNGKNKDC_02524 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NNGKNKDC_02525 3.19e-45 yoeD - - G - - - Helix-turn-helix domain
NNGKNKDC_02526 3.97e-125 - - - L - - - Integrase
NNGKNKDC_02528 6.1e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NNGKNKDC_02529 2.13e-311 yoeA - - V - - - MATE efflux family protein
NNGKNKDC_02530 2.63e-237 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNGKNKDC_02531 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NNGKNKDC_02532 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02533 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02534 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02535 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02536 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
NNGKNKDC_02537 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
NNGKNKDC_02538 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NNGKNKDC_02539 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NNGKNKDC_02540 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNGKNKDC_02541 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NNGKNKDC_02542 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NNGKNKDC_02543 2.01e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NNGKNKDC_02544 1.01e-177 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NNGKNKDC_02545 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNGKNKDC_02546 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
NNGKNKDC_02547 2.07e-205 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNGKNKDC_02548 2.26e-95 yngA - - S - - - membrane
NNGKNKDC_02549 1.44e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NNGKNKDC_02550 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NNGKNKDC_02551 3.95e-273 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNGKNKDC_02552 1.24e-165 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NNGKNKDC_02553 3.22e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NNGKNKDC_02554 2.16e-283 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNGKNKDC_02555 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NNGKNKDC_02556 2.45e-159 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNGKNKDC_02557 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNGKNKDC_02558 1.18e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NNGKNKDC_02559 4.56e-286 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNGKNKDC_02560 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02561 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02562 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02563 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NNGKNKDC_02564 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NNGKNKDC_02565 1.88e-164 - - - T - - - Transcriptional regulatory protein, C terminal
NNGKNKDC_02566 3.27e-310 - - - T - - - Histidine kinase
NNGKNKDC_02567 3.64e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
NNGKNKDC_02568 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NNGKNKDC_02570 4.68e-276 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
NNGKNKDC_02571 1.95e-32 yxlH - - EGP - - - Major Facilitator Superfamily
NNGKNKDC_02572 0.0 yndJ - - S - - - YndJ-like protein
NNGKNKDC_02573 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
NNGKNKDC_02574 2.72e-197 yndG - - S - - - DoxX-like family
NNGKNKDC_02575 7.9e-287 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
NNGKNKDC_02576 2.14e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
NNGKNKDC_02577 7.45e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_02578 1.73e-269 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NNGKNKDC_02579 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NNGKNKDC_02580 1.41e-240 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NNGKNKDC_02581 7.75e-232 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NNGKNKDC_02582 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NNGKNKDC_02583 1.82e-63 ynfC - - - - - - -
NNGKNKDC_02584 2.21e-19 - - - - - - - -
NNGKNKDC_02585 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNGKNKDC_02586 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNGKNKDC_02587 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NNGKNKDC_02588 5.25e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNGKNKDC_02589 3.13e-65 yneR - - S - - - Belongs to the HesB IscA family
NNGKNKDC_02590 7.79e-70 yneQ - - - - - - -
NNGKNKDC_02591 1.2e-96 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NNGKNKDC_02592 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NNGKNKDC_02594 6.99e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NNGKNKDC_02595 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NNGKNKDC_02596 1.47e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NNGKNKDC_02597 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NNGKNKDC_02598 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
NNGKNKDC_02599 9.74e-98 yneK - - S - - - Protein of unknown function (DUF2621)
NNGKNKDC_02600 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NNGKNKDC_02601 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NNGKNKDC_02602 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NNGKNKDC_02603 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
NNGKNKDC_02604 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NNGKNKDC_02605 1.26e-105 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NNGKNKDC_02606 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NNGKNKDC_02607 2.33e-43 ynzC - - S - - - UPF0291 protein
NNGKNKDC_02608 1.05e-144 yneB - - L - - - resolvase
NNGKNKDC_02609 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NNGKNKDC_02610 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNGKNKDC_02612 1.52e-93 yndM - - S - - - Protein of unknown function (DUF2512)
NNGKNKDC_02613 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NNGKNKDC_02614 1.74e-11 - - - - - - - -
NNGKNKDC_02615 2.37e-183 yndL - - S - - - Replication protein
NNGKNKDC_02616 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NNGKNKDC_02617 0.0 yobO - - M - - - Pectate lyase superfamily protein
NNGKNKDC_02619 6.53e-108 yvgO - - - - - - -
NNGKNKDC_02620 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNGKNKDC_02621 3.33e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
NNGKNKDC_02622 1.39e-256 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_02623 1.14e-144 - - - S - - - Domain of unknown function (DUF3885)
NNGKNKDC_02625 7.04e-82 - - - - - - - -
NNGKNKDC_02626 3.15e-126 - - - J - - - Acetyltransferase (GNAT) domain
NNGKNKDC_02627 6.89e-173 yoaP - - K - - - YoaP-like
NNGKNKDC_02628 5.45e-07 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NNGKNKDC_02629 2.02e-26 yoaW - - - - - - -
NNGKNKDC_02630 2.43e-95 - - - S - - - Bacterial transferase hexapeptide (six repeats)
NNGKNKDC_02631 1.7e-236 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NNGKNKDC_02632 5.71e-71 dinB - - S - - - DinB family
NNGKNKDC_02633 1.28e-26 - - - - - - - -
NNGKNKDC_02637 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NNGKNKDC_02638 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NNGKNKDC_02639 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NNGKNKDC_02640 2.22e-278 xylR - - GK - - - ROK family
NNGKNKDC_02641 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NNGKNKDC_02642 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NNGKNKDC_02647 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NNGKNKDC_02648 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NNGKNKDC_02649 3.37e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NNGKNKDC_02650 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNGKNKDC_02651 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NNGKNKDC_02652 3.22e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNGKNKDC_02666 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNGKNKDC_02667 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNGKNKDC_02668 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
NNGKNKDC_02669 1.3e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNGKNKDC_02670 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NNGKNKDC_02671 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNGKNKDC_02672 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNGKNKDC_02673 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNGKNKDC_02674 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNGKNKDC_02675 3.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NNGKNKDC_02676 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNGKNKDC_02677 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNGKNKDC_02678 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NNGKNKDC_02679 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NNGKNKDC_02680 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NNGKNKDC_02681 5.82e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNGKNKDC_02682 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
NNGKNKDC_02683 1.11e-106 yhhY - - K - - - FR47-like protein
NNGKNKDC_02684 2.37e-225 yyaD - - S - - - Membrane
NNGKNKDC_02685 1.82e-45 yyzM - - S - - - protein conserved in bacteria
NNGKNKDC_02686 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNGKNKDC_02687 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNGKNKDC_02688 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NNGKNKDC_02689 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNGKNKDC_02690 4.51e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNGKNKDC_02691 2.98e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NNGKNKDC_02692 2.12e-131 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNGKNKDC_02693 1.15e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NNGKNKDC_02694 1.19e-232 ccpB - - K - - - Transcriptional regulator
NNGKNKDC_02695 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_02696 3e-315 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NNGKNKDC_02697 3.86e-206 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNGKNKDC_02698 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NNGKNKDC_02699 0.0 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NNGKNKDC_02701 4.54e-91 ynaF - - - - - - -
NNGKNKDC_02702 1.02e-106 - - - - - - - -
NNGKNKDC_02703 4.29e-37 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NNGKNKDC_02704 2.45e-167 - - - EG - - - EamA-like transporter family
NNGKNKDC_02705 5.52e-315 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNGKNKDC_02706 7.86e-175 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NNGKNKDC_02707 1.41e-210 - - - K - - - Transcriptional regulator
NNGKNKDC_02708 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NNGKNKDC_02709 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
NNGKNKDC_02710 1.49e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
NNGKNKDC_02711 1.3e-99 yybA - - K - - - transcriptional
NNGKNKDC_02712 4.43e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_02713 1.37e-89 - - - K - - - Winged helix DNA-binding domain
NNGKNKDC_02714 1.7e-148 ydgI - - C - - - nitroreductase
NNGKNKDC_02715 2.01e-71 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NNGKNKDC_02716 5.48e-203 - - - G - - - Major Facilitator Superfamily
NNGKNKDC_02717 1.36e-117 - - - S - - - PFAM DinB family protein
NNGKNKDC_02718 8.03e-151 - - - K - - - FCD domain
NNGKNKDC_02719 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NNGKNKDC_02720 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NNGKNKDC_02721 1.24e-198 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNGKNKDC_02722 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NNGKNKDC_02723 1.08e-85 yybR - - K - - - Transcriptional regulator
NNGKNKDC_02724 4.44e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
NNGKNKDC_02726 9.68e-202 yybS - - S - - - membrane
NNGKNKDC_02727 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NNGKNKDC_02728 6.45e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NNGKNKDC_02729 1.51e-160 - - - KLT - - - COG0515 Serine threonine protein kinase
NNGKNKDC_02730 1.07e-157 - - - S - - - GlcNAc-PI de-N-acetylase
NNGKNKDC_02731 1.95e-307 - - - M - - - Glycosyltransferase Family 4
NNGKNKDC_02732 6.85e-299 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
NNGKNKDC_02733 4.68e-261 - - - S - - - Ecdysteroid kinase
NNGKNKDC_02734 3.32e-301 - - - M - - - Glycosyltransferase Family 4
NNGKNKDC_02735 3.6e-25 yycC - - K - - - YycC-like protein
NNGKNKDC_02737 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NNGKNKDC_02738 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NNGKNKDC_02739 5.26e-93 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_02740 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNGKNKDC_02745 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_02746 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02747 0.0 yycH - - S - - - protein conserved in bacteria
NNGKNKDC_02748 1.14e-193 yycI - - S - - - protein conserved in bacteria
NNGKNKDC_02749 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NNGKNKDC_02750 2.31e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNGKNKDC_02751 1.34e-13 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_02752 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNGKNKDC_02753 2.51e-245 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
NNGKNKDC_02754 0.0 - - - - - - - -
NNGKNKDC_02755 1.85e-252 - - - S - - - Major Facilitator Superfamily
NNGKNKDC_02756 0.0 - - - S - - - ABC transporter
NNGKNKDC_02757 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
NNGKNKDC_02758 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NNGKNKDC_02759 2.69e-57 sdpR - - K - - - transcriptional
NNGKNKDC_02760 3.6e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NNGKNKDC_02761 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NNGKNKDC_02762 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNGKNKDC_02763 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NNGKNKDC_02764 3.31e-262 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NNGKNKDC_02766 1.1e-108 yycN - - K - - - Acetyltransferase
NNGKNKDC_02767 2.92e-231 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NNGKNKDC_02768 5e-171 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NNGKNKDC_02769 1.98e-278 yycP - - - - - - -
NNGKNKDC_02772 1.67e-104 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNGKNKDC_02773 6.25e-116 - - - K - - - NAD+ binding
NNGKNKDC_02774 1.14e-96 - - - F - - - 5-carbamoylmethyl uridine residue modification
NNGKNKDC_02775 0.0 - - - L - - - AAA domain
NNGKNKDC_02776 1.85e-26 - - - - - - - -
NNGKNKDC_02777 8.85e-232 - - - S - - - Fusaric acid resistance protein-like
NNGKNKDC_02778 2.25e-241 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NNGKNKDC_02779 1.85e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NNGKNKDC_02780 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NNGKNKDC_02781 6.65e-198 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NNGKNKDC_02782 5.75e-109 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NNGKNKDC_02783 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NNGKNKDC_02784 6.13e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_02785 1.13e-291 - - - S - - - Fic/DOC family
NNGKNKDC_02786 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NNGKNKDC_02787 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NNGKNKDC_02788 3.03e-159 - - - E - - - Ring-cleavage extradiol dioxygenase
NNGKNKDC_02789 2.61e-95 yxaI - - S - - - membrane protein domain
NNGKNKDC_02790 7.67e-256 - - - EGP - - - Major Facilitator Superfamily
NNGKNKDC_02791 2.86e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKNKDC_02792 1.81e-78 - - - S - - - Family of unknown function (DUF5391)
NNGKNKDC_02793 3.25e-189 yxaL - - S - - - PQQ-like domain
NNGKNKDC_02794 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNGKNKDC_02795 6.32e-274 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NNGKNKDC_02796 1.83e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NNGKNKDC_02797 2.49e-256 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02798 5.28e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNGKNKDC_02799 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_02801 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NNGKNKDC_02802 4.5e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNGKNKDC_02803 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NNGKNKDC_02804 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNGKNKDC_02805 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNGKNKDC_02806 8.13e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NNGKNKDC_02807 5.66e-231 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NNGKNKDC_02808 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NNGKNKDC_02809 4.62e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NNGKNKDC_02810 2.12e-293 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NNGKNKDC_02811 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NNGKNKDC_02812 1.79e-211 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NNGKNKDC_02813 3.58e-202 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NNGKNKDC_02814 1.15e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NNGKNKDC_02815 1.09e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_02816 4.59e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02817 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_02818 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNGKNKDC_02819 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
NNGKNKDC_02820 1.13e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NNGKNKDC_02821 3.25e-45 - - - - - - - -
NNGKNKDC_02822 5.09e-35 yxeD - - - - - - -
NNGKNKDC_02823 9.71e-41 yxeE - - - - - - -
NNGKNKDC_02826 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
NNGKNKDC_02827 5.8e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNGKNKDC_02828 1.67e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NNGKNKDC_02829 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNGKNKDC_02830 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NNGKNKDC_02831 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNGKNKDC_02832 1.68e-225 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NNGKNKDC_02833 1.57e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NNGKNKDC_02834 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NNGKNKDC_02835 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NNGKNKDC_02836 1.42e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NNGKNKDC_02837 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NNGKNKDC_02838 5.08e-82 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NNGKNKDC_02840 0.0 - - - L - - - HKD family nuclease
NNGKNKDC_02841 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02842 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKNKDC_02843 1.79e-96 yxiE - - T - - - Belongs to the universal stress protein A family
NNGKNKDC_02844 7.23e-209 yxxF - - EG - - - EamA-like transporter family
NNGKNKDC_02845 3.83e-257 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NNGKNKDC_02846 0.0 wapA - - M - - - COG3209 Rhs family protein
NNGKNKDC_02850 2.38e-27 - - - - - - - -
NNGKNKDC_02852 9.56e-109 yxiI - - S - - - Protein of unknown function (DUF2716)
NNGKNKDC_02853 3.22e-41 - - - S - - - SMI1-KNR4 cell-wall
NNGKNKDC_02854 4.89e-12 - - - S - - - SMI1-KNR4 cell-wall
NNGKNKDC_02857 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NNGKNKDC_02858 4.27e-281 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NNGKNKDC_02859 4.85e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NNGKNKDC_02860 3.44e-186 bglS - - M - - - licheninase activity
NNGKNKDC_02861 3.86e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NNGKNKDC_02862 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNGKNKDC_02863 2.68e-67 yxiS - - - - - - -
NNGKNKDC_02864 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
NNGKNKDC_02865 2.72e-266 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNGKNKDC_02866 1.1e-202 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NNGKNKDC_02867 2.57e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NNGKNKDC_02868 7.42e-112 yxjI - - S - - - LURP-one-related
NNGKNKDC_02871 5.46e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NNGKNKDC_02872 1.87e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNGKNKDC_02873 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
NNGKNKDC_02874 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNGKNKDC_02875 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NNGKNKDC_02876 1.06e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNGKNKDC_02877 2.83e-199 yxkH - - G - - - Polysaccharide deacetylase
NNGKNKDC_02878 6.44e-287 cimH - - C - - - COG3493 Na citrate symporter
NNGKNKDC_02879 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NNGKNKDC_02880 1.77e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NNGKNKDC_02881 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NNGKNKDC_02882 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NNGKNKDC_02883 3.58e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNGKNKDC_02884 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NNGKNKDC_02885 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NNGKNKDC_02886 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNGKNKDC_02887 3.75e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NNGKNKDC_02888 4.71e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNGKNKDC_02889 1.26e-213 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NNGKNKDC_02890 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKNKDC_02891 3.47e-303 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKNKDC_02892 3.22e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02893 1.39e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02894 1.55e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNGKNKDC_02895 7.5e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NNGKNKDC_02896 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NNGKNKDC_02897 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_02898 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_02899 1.08e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NNGKNKDC_02900 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NNGKNKDC_02901 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NNGKNKDC_02902 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKNKDC_02903 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_02904 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNGKNKDC_02905 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNGKNKDC_02906 2.54e-288 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNGKNKDC_02907 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02908 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NNGKNKDC_02909 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_02910 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NNGKNKDC_02911 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NNGKNKDC_02912 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NNGKNKDC_02913 8.59e-207 gspA - - M - - - General stress
NNGKNKDC_02914 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNGKNKDC_02915 1.1e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNGKNKDC_02916 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NNGKNKDC_02917 2.53e-285 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NNGKNKDC_02918 5.83e-206 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NNGKNKDC_02919 3.99e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NNGKNKDC_02920 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02921 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02922 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_02923 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NNGKNKDC_02924 8.08e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNGKNKDC_02925 3.74e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NNGKNKDC_02926 5.64e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NNGKNKDC_02927 2.88e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNGKNKDC_02928 2.38e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNGKNKDC_02929 4.13e-181 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNGKNKDC_02930 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NNGKNKDC_02931 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NNGKNKDC_02932 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_02934 4.13e-238 yueF - - S - - - transporter activity
NNGKNKDC_02936 9.19e-76 - - - S - - - YolD-like protein
NNGKNKDC_02937 6.63e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNGKNKDC_02938 4.67e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NNGKNKDC_02939 1.41e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NNGKNKDC_02940 1.06e-225 yqkA - - K - - - GrpB protein
NNGKNKDC_02941 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
NNGKNKDC_02942 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
NNGKNKDC_02943 2.46e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNGKNKDC_02944 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
NNGKNKDC_02945 3.77e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NNGKNKDC_02946 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
NNGKNKDC_02947 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NNGKNKDC_02948 3.28e-277 yqxK - - L - - - DNA helicase
NNGKNKDC_02949 6.9e-77 ansR - - K - - - Transcriptional regulator
NNGKNKDC_02950 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NNGKNKDC_02951 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NNGKNKDC_02952 8.36e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NNGKNKDC_02953 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NNGKNKDC_02954 1.96e-30 - - - - - - - -
NNGKNKDC_02955 4.38e-47 yqkK - - - - - - -
NNGKNKDC_02957 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NNGKNKDC_02958 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NNGKNKDC_02959 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
NNGKNKDC_02960 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NNGKNKDC_02961 2.88e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNGKNKDC_02962 1.83e-191 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NNGKNKDC_02963 2.47e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNGKNKDC_02964 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NNGKNKDC_02965 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NNGKNKDC_02966 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_02967 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NNGKNKDC_02968 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NNGKNKDC_02969 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NNGKNKDC_02970 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NNGKNKDC_02971 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NNGKNKDC_02972 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
NNGKNKDC_02973 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NNGKNKDC_02974 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNGKNKDC_02975 5.64e-200 ypuA - - S - - - Secreted protein
NNGKNKDC_02976 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNGKNKDC_02977 3.35e-106 ccdC1 - - O - - - Protein of unknown function (DUF1453)
NNGKNKDC_02978 1.09e-129 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNGKNKDC_02979 4.92e-71 ypuD - - - - - - -
NNGKNKDC_02980 1.31e-268 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NNGKNKDC_02981 5.64e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NNGKNKDC_02982 4.95e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NNGKNKDC_02983 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NNGKNKDC_02984 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNGKNKDC_02985 6.67e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NNGKNKDC_02987 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNGKNKDC_02988 3.19e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNGKNKDC_02989 4.32e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
NNGKNKDC_02990 1.62e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNGKNKDC_02991 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NNGKNKDC_02992 2.58e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NNGKNKDC_02993 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNGKNKDC_02994 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NNGKNKDC_02995 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NNGKNKDC_02996 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NNGKNKDC_02997 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_02998 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_02999 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_03000 2.67e-252 rsiX - - - - - - -
NNGKNKDC_03001 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNGKNKDC_03002 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNGKNKDC_03003 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NNGKNKDC_03004 5.83e-251 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NNGKNKDC_03005 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNGKNKDC_03006 3.13e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NNGKNKDC_03007 5.85e-124 ypbE - - M - - - Lysin motif
NNGKNKDC_03008 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
NNGKNKDC_03009 4.01e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NNGKNKDC_03010 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNGKNKDC_03011 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNGKNKDC_03012 5.3e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NNGKNKDC_03013 1.84e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NNGKNKDC_03014 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NNGKNKDC_03015 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NNGKNKDC_03016 4.07e-78 ypfA - - M - - - Flagellar protein YcgR
NNGKNKDC_03017 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
NNGKNKDC_03018 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NNGKNKDC_03019 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NNGKNKDC_03020 5.92e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNGKNKDC_03021 1.87e-12 - - - S - - - YpzI-like protein
NNGKNKDC_03022 6.19e-136 yphA - - - - - - -
NNGKNKDC_03023 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NNGKNKDC_03024 1.41e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NNGKNKDC_03025 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
NNGKNKDC_03026 3.4e-173 yphF - - - - - - -
NNGKNKDC_03027 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NNGKNKDC_03028 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNGKNKDC_03029 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NNGKNKDC_03030 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NNGKNKDC_03031 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NNGKNKDC_03032 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NNGKNKDC_03033 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNGKNKDC_03034 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NNGKNKDC_03035 1.5e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NNGKNKDC_03036 1.14e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NNGKNKDC_03037 5.26e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NNGKNKDC_03038 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NNGKNKDC_03039 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNGKNKDC_03040 5.82e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NNGKNKDC_03041 1.17e-167 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NNGKNKDC_03042 1.24e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NNGKNKDC_03043 1.73e-290 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NNGKNKDC_03044 1.14e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NNGKNKDC_03045 6.85e-254 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NNGKNKDC_03046 8.76e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NNGKNKDC_03047 1.71e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NNGKNKDC_03048 2.5e-297 ypiA - - S - - - COG0457 FOG TPR repeat
NNGKNKDC_03049 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
NNGKNKDC_03050 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
NNGKNKDC_03051 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NNGKNKDC_03052 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NNGKNKDC_03053 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NNGKNKDC_03054 7.24e-134 ypjA - - S - - - membrane
NNGKNKDC_03055 2.05e-182 ypjB - - S - - - sporulation protein
NNGKNKDC_03056 2.25e-286 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NNGKNKDC_03057 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_03058 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NNGKNKDC_03059 1.62e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNGKNKDC_03060 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NNGKNKDC_03061 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NNGKNKDC_03062 8.91e-270 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NNGKNKDC_03063 3.82e-276 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNGKNKDC_03064 2.7e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNGKNKDC_03065 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NNGKNKDC_03066 6.95e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NNGKNKDC_03067 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NNGKNKDC_03068 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NNGKNKDC_03069 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NNGKNKDC_03070 2.77e-104 ypmB - - S - - - protein conserved in bacteria
NNGKNKDC_03071 5.95e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNGKNKDC_03072 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NNGKNKDC_03073 1.39e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NNGKNKDC_03074 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNGKNKDC_03075 1.04e-118 ypoC - - - - - - -
NNGKNKDC_03076 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNGKNKDC_03077 7.27e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNGKNKDC_03078 2.73e-237 yppC - - S - - - Protein of unknown function (DUF2515)
NNGKNKDC_03079 0.000542 - - - - ko:K06430 - ko00000 -
NNGKNKDC_03083 9.16e-75 yppG - - S - - - YppG-like protein
NNGKNKDC_03084 5.29e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNGKNKDC_03085 1.65e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NNGKNKDC_03086 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NNGKNKDC_03087 9.47e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NNGKNKDC_03089 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NNGKNKDC_03090 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
NNGKNKDC_03091 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNGKNKDC_03092 5.34e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NNGKNKDC_03093 6.91e-31 - - - S - - - YpzG-like protein
NNGKNKDC_03095 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NNGKNKDC_03096 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NNGKNKDC_03097 2e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNGKNKDC_03098 1.19e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
NNGKNKDC_03099 7.89e-08 - - - S - - - Bacillus cereus group antimicrobial protein
NNGKNKDC_03100 8.93e-130 yrdC - - Q - - - Isochorismatase family
NNGKNKDC_03101 4.53e-126 ydfR - - S - - - Protein of unknown function (DUF421)
NNGKNKDC_03102 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
NNGKNKDC_03103 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NNGKNKDC_03104 2.94e-135 - - - J - - - Acetyltransferase (GNAT) domain
NNGKNKDC_03105 2.54e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NNGKNKDC_03106 1.79e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NNGKNKDC_03107 0.0 ypbR - - S - - - Dynamin family
NNGKNKDC_03108 5.79e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
NNGKNKDC_03109 2.44e-10 - - - - - - - -
NNGKNKDC_03110 2.25e-208 ypcP - - L - - - 5'3' exonuclease
NNGKNKDC_03112 4.99e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NNGKNKDC_03113 1.14e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NNGKNKDC_03114 5.91e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NNGKNKDC_03115 6.59e-40 ypeQ - - S - - - Zinc-finger
NNGKNKDC_03116 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
NNGKNKDC_03117 5.19e-17 degR - - - - - - -
NNGKNKDC_03118 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NNGKNKDC_03119 1.49e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NNGKNKDC_03120 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NNGKNKDC_03121 3.93e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NNGKNKDC_03122 2.29e-128 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NNGKNKDC_03123 5.44e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NNGKNKDC_03124 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NNGKNKDC_03125 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
NNGKNKDC_03126 3.49e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NNGKNKDC_03127 6.48e-148 ypjP - - S - - - YpjP-like protein
NNGKNKDC_03128 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNGKNKDC_03129 3.01e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNGKNKDC_03130 1.64e-148 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNGKNKDC_03131 4.79e-100 yclD - - - - - - -
NNGKNKDC_03132 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NNGKNKDC_03133 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NNGKNKDC_03134 4.02e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NNGKNKDC_03135 2.43e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NNGKNKDC_03136 1.89e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NNGKNKDC_03137 1.23e-153 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNGKNKDC_03138 5.61e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNGKNKDC_03139 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
NNGKNKDC_03140 2.15e-166 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NNGKNKDC_03141 2.92e-314 ycxD - - K - - - GntR family transcriptional regulator
NNGKNKDC_03142 5.53e-217 ycxC - - EG - - - EamA-like transporter family
NNGKNKDC_03143 3.86e-84 - - - S - - - YcxB-like protein
NNGKNKDC_03144 1.91e-316 - - - E - - - Aminotransferase class I and II
NNGKNKDC_03145 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NNGKNKDC_03146 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NNGKNKDC_03147 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_03148 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_03149 4.1e-84 hxlR - - K - - - transcriptional
NNGKNKDC_03150 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NNGKNKDC_03151 1.8e-123 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NNGKNKDC_03152 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
NNGKNKDC_03153 5.81e-92 nin - - S - - - Competence protein J (ComJ)
NNGKNKDC_03154 5.53e-42 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNGKNKDC_03155 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
NNGKNKDC_03156 2.2e-95 yckC - - S - - - membrane
NNGKNKDC_03157 7.48e-283 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNGKNKDC_03158 3.35e-288 yciC - - S - - - GTPases (G3E family)
NNGKNKDC_03159 4.72e-284 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NNGKNKDC_03160 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NNGKNKDC_03161 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNGKNKDC_03162 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NNGKNKDC_03163 6.96e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NNGKNKDC_03164 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NNGKNKDC_03165 4.54e-240 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NNGKNKDC_03166 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NNGKNKDC_03167 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNGKNKDC_03168 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNGKNKDC_03169 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NNGKNKDC_03170 9.32e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NNGKNKDC_03171 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NNGKNKDC_03172 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NNGKNKDC_03173 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03174 1.66e-173 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NNGKNKDC_03175 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
NNGKNKDC_03176 3.16e-192 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNGKNKDC_03177 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NNGKNKDC_03178 9.42e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_03179 2.42e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NNGKNKDC_03180 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
NNGKNKDC_03181 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_03182 0.0 mdr - - EGP - - - the major facilitator superfamily
NNGKNKDC_03183 1.39e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NNGKNKDC_03184 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NNGKNKDC_03185 4.41e-106 ycgB - - - - - - -
NNGKNKDC_03186 6.59e-293 ycgA - - S - - - Membrane
NNGKNKDC_03187 1.26e-267 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NNGKNKDC_03188 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NNGKNKDC_03189 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NNGKNKDC_03190 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NNGKNKDC_03191 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NNGKNKDC_03192 3.34e-246 yceH - - P - - - Belongs to the TelA family
NNGKNKDC_03193 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NNGKNKDC_03194 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NNGKNKDC_03195 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NNGKNKDC_03196 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NNGKNKDC_03197 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NNGKNKDC_03198 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNGKNKDC_03199 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NNGKNKDC_03200 4.01e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NNGKNKDC_03201 7.35e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NNGKNKDC_03202 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNGKNKDC_03203 8.64e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_03204 5.77e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NNGKNKDC_03205 7.3e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NNGKNKDC_03206 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_03207 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_03208 1.13e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
NNGKNKDC_03209 2.18e-218 yccK - - C - - - Aldo keto reductase
NNGKNKDC_03210 7.97e-251 yccF - - K ko:K07039 - ko00000 SEC-C motif
NNGKNKDC_03211 3.29e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NNGKNKDC_03212 1.88e-252 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NNGKNKDC_03213 2.19e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NNGKNKDC_03214 2.5e-313 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NNGKNKDC_03215 1.35e-263 ycbU - - E - - - Selenocysteine lyase
NNGKNKDC_03216 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NNGKNKDC_03217 1.22e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNGKNKDC_03218 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNGKNKDC_03219 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NNGKNKDC_03220 1.33e-104 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NNGKNKDC_03221 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
NNGKNKDC_03222 5.37e-74 ydfQ - - CO - - - Thioredoxin
NNGKNKDC_03223 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
NNGKNKDC_03224 1.02e-233 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNGKNKDC_03225 4.7e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NNGKNKDC_03226 4.28e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNGKNKDC_03227 3.06e-40 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NNGKNKDC_03228 1.31e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NNGKNKDC_03229 1.03e-277 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_03230 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NNGKNKDC_03231 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NNGKNKDC_03232 2.8e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NNGKNKDC_03233 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNGKNKDC_03234 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNGKNKDC_03235 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNGKNKDC_03236 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NNGKNKDC_03237 3.02e-55 ybfN - - - - - - -
NNGKNKDC_03238 3.05e-194 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NNGKNKDC_03239 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
NNGKNKDC_03240 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNGKNKDC_03241 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNGKNKDC_03242 3.68e-256 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NNGKNKDC_03243 5.66e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
NNGKNKDC_03244 2.44e-45 - - - - - - - -
NNGKNKDC_03245 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
NNGKNKDC_03247 1.17e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NNGKNKDC_03248 7.91e-23 - - - S - - - Protein of unknown function (DUF2651)
NNGKNKDC_03249 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NNGKNKDC_03250 1.41e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NNGKNKDC_03251 7.3e-22 - - - S - - - Protein of unknown function (DUF2651)
NNGKNKDC_03253 0.0 ybeC - - E - - - amino acid
NNGKNKDC_03254 7.84e-55 ybyB - - - - - - -
NNGKNKDC_03255 2.8e-141 yqeB - - - - - - -
NNGKNKDC_03256 5.87e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NNGKNKDC_03257 8.99e-104 - - - S - - - Domain of unknown function (DUF4879)
NNGKNKDC_03258 2.34e-35 - - - - - - - -
NNGKNKDC_03259 1.61e-253 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NNGKNKDC_03260 1.19e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NNGKNKDC_03261 1.53e-214 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NNGKNKDC_03262 1.68e-140 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NNGKNKDC_03263 4.49e-258 - - - T - - - COG4585 Signal transduction histidine kinase
NNGKNKDC_03264 2.64e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NNGKNKDC_03265 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNGKNKDC_03267 4.11e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_03268 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NNGKNKDC_03269 7.37e-136 yxaC - - M - - - effector of murein hydrolase
NNGKNKDC_03270 2.54e-207 dkgB - - S - - - Aldo/keto reductase family
NNGKNKDC_03271 5.04e-167 ybdO - - S - - - Domain of unknown function (DUF4885)
NNGKNKDC_03272 1.78e-121 ybdN - - - - - - -
NNGKNKDC_03274 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNGKNKDC_03275 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNGKNKDC_03276 1.5e-299 ybbR - - S - - - protein conserved in bacteria
NNGKNKDC_03277 6.33e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNGKNKDC_03278 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NNGKNKDC_03279 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNGKNKDC_03285 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
NNGKNKDC_03286 1.82e-112 ybbJ - - J - - - acetyltransferase
NNGKNKDC_03287 1.91e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NNGKNKDC_03288 4.13e-310 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_03289 7.99e-312 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NNGKNKDC_03290 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NNGKNKDC_03291 2.72e-301 ybbC - - S - - - protein conserved in bacteria
NNGKNKDC_03292 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NNGKNKDC_03293 2.86e-218 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NNGKNKDC_03294 8.92e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_03295 2.04e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNGKNKDC_03296 9.18e-131 ybbA - - S ko:K07017 - ko00000 Putative esterase
NNGKNKDC_03297 1.87e-223 ybaS - - S - - - Na -dependent transporter
NNGKNKDC_03298 1.84e-286 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NNGKNKDC_03299 1.55e-253 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NNGKNKDC_03300 9.42e-232 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
NNGKNKDC_03301 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNGKNKDC_03302 3.7e-280 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NNGKNKDC_03303 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
NNGKNKDC_03304 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNGKNKDC_03305 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NNGKNKDC_03306 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
NNGKNKDC_03307 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNGKNKDC_03308 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNGKNKDC_03309 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNGKNKDC_03310 3.63e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNGKNKDC_03311 4.44e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNGKNKDC_03312 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NNGKNKDC_03313 4.53e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NNGKNKDC_03314 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
NNGKNKDC_03315 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NNGKNKDC_03316 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NNGKNKDC_03317 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NNGKNKDC_03318 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NNGKNKDC_03319 1.78e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NNGKNKDC_03320 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NNGKNKDC_03321 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NNGKNKDC_03322 1.07e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NNGKNKDC_03323 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NNGKNKDC_03324 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NNGKNKDC_03325 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NNGKNKDC_03326 4.03e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NNGKNKDC_03327 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
NNGKNKDC_03328 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
NNGKNKDC_03329 1.9e-56 ysdA - - S - - - Membrane
NNGKNKDC_03330 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNGKNKDC_03331 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NNGKNKDC_03332 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNGKNKDC_03333 1.26e-146 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NNGKNKDC_03334 1.12e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
NNGKNKDC_03335 1.49e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NNGKNKDC_03336 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNGKNKDC_03337 1.7e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NNGKNKDC_03338 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNGKNKDC_03339 3.85e-195 ytxC - - S - - - YtxC-like family
NNGKNKDC_03340 1.05e-138 ytxB - - S - - - SNARE associated Golgi protein
NNGKNKDC_03341 4.08e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NNGKNKDC_03342 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NNGKNKDC_03343 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNGKNKDC_03344 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NNGKNKDC_03345 8.93e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNGKNKDC_03346 1.69e-89 ytcD - - K - - - Transcriptional regulator
NNGKNKDC_03347 3.4e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NNGKNKDC_03348 4.54e-205 ytbE - - S - - - reductase
NNGKNKDC_03349 5.08e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNGKNKDC_03350 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
NNGKNKDC_03351 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNGKNKDC_03352 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNGKNKDC_03353 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NNGKNKDC_03354 4.82e-166 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_03355 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NNGKNKDC_03356 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NNGKNKDC_03357 5.78e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNGKNKDC_03358 7.81e-69 - - - - - - - -
NNGKNKDC_03359 7.81e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NNGKNKDC_03360 2.3e-95 ytwI - - S - - - membrane
NNGKNKDC_03361 1.65e-246 ytvI - - S - - - sporulation integral membrane protein YtvI
NNGKNKDC_03362 2.41e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NNGKNKDC_03363 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NNGKNKDC_03364 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNGKNKDC_03365 4.67e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NNGKNKDC_03366 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNGKNKDC_03367 1.48e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NNGKNKDC_03368 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NNGKNKDC_03369 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
NNGKNKDC_03370 2.64e-114 ytrI - - - - - - -
NNGKNKDC_03371 7.04e-32 - - - - - - - -
NNGKNKDC_03372 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NNGKNKDC_03373 3.57e-62 ytpI - - S - - - YtpI-like protein
NNGKNKDC_03374 1.94e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
NNGKNKDC_03375 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
NNGKNKDC_03376 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNGKNKDC_03378 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNGKNKDC_03379 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNGKNKDC_03380 1.35e-113 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NNGKNKDC_03381 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNGKNKDC_03382 1.24e-233 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NNGKNKDC_03383 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNGKNKDC_03384 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
NNGKNKDC_03385 2.12e-155 ytfI - - S - - - Protein of unknown function (DUF2953)
NNGKNKDC_03386 2.77e-114 yteJ - - S - - - RDD family
NNGKNKDC_03387 3.7e-234 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NNGKNKDC_03388 6.65e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNGKNKDC_03389 0.0 ytcJ - - S - - - amidohydrolase
NNGKNKDC_03390 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNGKNKDC_03391 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NNGKNKDC_03392 1.47e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNGKNKDC_03393 7.87e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNGKNKDC_03394 3.39e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NNGKNKDC_03395 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNGKNKDC_03396 2.16e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NNGKNKDC_03397 2.41e-141 yttP - - K - - - Transcriptional regulator
NNGKNKDC_03398 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NNGKNKDC_03399 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NNGKNKDC_03400 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNGKNKDC_03401 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNGKNKDC_03402 3.38e-128 yokH - - G - - - SMI1 / KNR4 family
NNGKNKDC_03404 2.15e-69 - - - UW ko:K06236,ko:K07061 ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165 ko00000,ko00001,ko00536,ko02048,ko04516 Hep Hag repeat protein
NNGKNKDC_03405 8.77e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NNGKNKDC_03407 3.89e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NNGKNKDC_03409 8.7e-179 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNGKNKDC_03410 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNGKNKDC_03411 3.16e-190 - - - K - - - Transcriptional regulator
NNGKNKDC_03412 5.77e-160 ygaZ - - E - - - AzlC protein
NNGKNKDC_03413 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NNGKNKDC_03414 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNGKNKDC_03415 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNGKNKDC_03416 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NNGKNKDC_03417 2.93e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NNGKNKDC_03418 4.07e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NNGKNKDC_03419 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NNGKNKDC_03420 8.63e-185 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NNGKNKDC_03421 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NNGKNKDC_03422 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NNGKNKDC_03423 1.45e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
NNGKNKDC_03424 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NNGKNKDC_03425 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNGKNKDC_03426 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NNGKNKDC_03427 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNGKNKDC_03428 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNGKNKDC_03429 9.78e-190 ytpQ - - S - - - Belongs to the UPF0354 family
NNGKNKDC_03430 5.47e-76 ytpP - - CO - - - Thioredoxin
NNGKNKDC_03431 5.77e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NNGKNKDC_03432 2.35e-90 - - - T - - - HPP family
NNGKNKDC_03433 1.59e-82 - - - S - - - Putative stress-induced transcription regulator
NNGKNKDC_03434 3.56e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NNGKNKDC_03435 9.96e-69 ytzB - - S - - - small secreted protein
NNGKNKDC_03436 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NNGKNKDC_03437 5.33e-209 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNGKNKDC_03438 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNGKNKDC_03439 2.25e-59 ytzH - - S - - - YtzH-like protein
NNGKNKDC_03440 2.93e-199 ytmP - - M - - - Phosphotransferase
NNGKNKDC_03441 3.96e-225 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNGKNKDC_03442 6.26e-218 ytlQ - - - - - - -
NNGKNKDC_03443 1.82e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NNGKNKDC_03444 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNGKNKDC_03445 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NNGKNKDC_03446 1.22e-289 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NNGKNKDC_03447 1.44e-275 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NNGKNKDC_03448 4.65e-166 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNGKNKDC_03449 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NNGKNKDC_03450 1.44e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNGKNKDC_03451 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNGKNKDC_03452 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NNGKNKDC_03453 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NNGKNKDC_03454 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NNGKNKDC_03455 5.27e-237 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NNGKNKDC_03456 9.3e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NNGKNKDC_03457 3.09e-215 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNGKNKDC_03458 3.37e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNGKNKDC_03459 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NNGKNKDC_03460 6.26e-62 - - - M - - - Acetyltransferase (GNAT) domain
NNGKNKDC_03461 1.24e-34 - - - M - - - Acetyltransferase (GNAT) domain
NNGKNKDC_03462 1.43e-67 ytwF - - P - - - Sulfurtransferase
NNGKNKDC_03463 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NNGKNKDC_03464 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
NNGKNKDC_03465 5.59e-176 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NNGKNKDC_03466 3.74e-266 yttB - - EGP - - - Major facilitator superfamily
NNGKNKDC_03467 1.32e-163 ywaF - - S - - - Integral membrane protein
NNGKNKDC_03468 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NNGKNKDC_03469 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_03470 1.43e-226 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NNGKNKDC_03471 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNGKNKDC_03472 1.36e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NNGKNKDC_03473 3.01e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_03474 1e-206 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NNGKNKDC_03475 1.06e-234 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNGKNKDC_03476 6.05e-225 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNGKNKDC_03477 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNGKNKDC_03478 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NNGKNKDC_03480 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
NNGKNKDC_03481 0.0 - - - IQ - - - AMP-binding enzyme
NNGKNKDC_03482 1.2e-261 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNGKNKDC_03483 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNGKNKDC_03484 2.3e-265 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNGKNKDC_03485 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
NNGKNKDC_03486 5.48e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NNGKNKDC_03487 1.89e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNGKNKDC_03488 1.87e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NNGKNKDC_03489 3.76e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNGKNKDC_03490 9.51e-47 yrhC - - S - - - YrhC-like protein
NNGKNKDC_03491 3.22e-104 yrhD - - S - - - Protein of unknown function (DUF1641)
NNGKNKDC_03492 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNGKNKDC_03493 6.26e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NNGKNKDC_03494 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NNGKNKDC_03495 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NNGKNKDC_03496 9.01e-121 yrhH - - Q - - - methyltransferase
NNGKNKDC_03497 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NNGKNKDC_03498 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NNGKNKDC_03499 9.26e-271 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03500 2.64e-211 yybE - - K - - - Transcriptional regulator
NNGKNKDC_03501 2.29e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NNGKNKDC_03502 3.42e-233 romA - - S - - - Beta-lactamase superfamily domain
NNGKNKDC_03503 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NNGKNKDC_03504 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_03505 2.52e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNGKNKDC_03506 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
NNGKNKDC_03507 5.02e-188 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNGKNKDC_03508 5.66e-188 supH - - S - - - hydrolase
NNGKNKDC_03510 1.37e-120 - - - S - - - DinB family
NNGKNKDC_03511 1.01e-103 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NNGKNKDC_03512 7.48e-89 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03513 7.45e-41 - - - K - - - acetyltransferase
NNGKNKDC_03514 9.1e-127 yqaC - - F - - - adenylate kinase activity
NNGKNKDC_03515 3.27e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
NNGKNKDC_03517 9.81e-279 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NNGKNKDC_03518 1.33e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
NNGKNKDC_03519 7.32e-306 yrkQ - - T - - - Histidine kinase
NNGKNKDC_03520 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
NNGKNKDC_03521 1.51e-117 - - - K - - - Transcriptional regulator PadR-like family
NNGKNKDC_03522 2.63e-204 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NNGKNKDC_03523 2.27e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNGKNKDC_03524 2.7e-278 - - - EGP - - - Transmembrane secretion effector
NNGKNKDC_03525 2.22e-34 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNGKNKDC_03526 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
NNGKNKDC_03527 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NNGKNKDC_03528 3.59e-178 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NNGKNKDC_03530 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NNGKNKDC_03531 7.93e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NNGKNKDC_03532 6.94e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNGKNKDC_03533 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NNGKNKDC_03534 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNGKNKDC_03535 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NNGKNKDC_03536 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNGKNKDC_03537 2.31e-176 yqeM - - Q - - - Methyltransferase
NNGKNKDC_03538 9.38e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNGKNKDC_03539 1.39e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NNGKNKDC_03540 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NNGKNKDC_03541 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NNGKNKDC_03542 4.48e-233 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NNGKNKDC_03543 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NNGKNKDC_03544 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NNGKNKDC_03545 5.25e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NNGKNKDC_03546 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
NNGKNKDC_03547 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNGKNKDC_03548 6.84e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NNGKNKDC_03549 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNGKNKDC_03550 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNGKNKDC_03551 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NNGKNKDC_03552 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNGKNKDC_03553 4.44e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NNGKNKDC_03554 5.03e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNGKNKDC_03555 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NNGKNKDC_03556 5.59e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NNGKNKDC_03557 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NNGKNKDC_03558 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NNGKNKDC_03559 4.66e-296 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NNGKNKDC_03560 2.76e-176 yqfA - - S - - - UPF0365 protein
NNGKNKDC_03561 8.89e-86 yqfB - - - - - - -
NNGKNKDC_03562 3.57e-61 yqfC - - S - - - sporulation protein YqfC
NNGKNKDC_03563 1.58e-283 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NNGKNKDC_03564 4.1e-223 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NNGKNKDC_03565 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NNGKNKDC_03566 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNGKNKDC_03567 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NNGKNKDC_03568 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NNGKNKDC_03569 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNGKNKDC_03570 6e-24 - - - S - - - YqzL-like protein
NNGKNKDC_03571 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NNGKNKDC_03572 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NNGKNKDC_03573 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NNGKNKDC_03574 5.89e-145 ccpN - - K - - - CBS domain
NNGKNKDC_03575 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNGKNKDC_03576 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NNGKNKDC_03577 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNGKNKDC_03578 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNGKNKDC_03579 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NNGKNKDC_03580 1.72e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NNGKNKDC_03581 1.53e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNGKNKDC_03582 3.53e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NNGKNKDC_03583 4.16e-89 yqfQ - - S - - - YqfQ-like protein
NNGKNKDC_03584 3.42e-314 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNGKNKDC_03585 3.48e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NNGKNKDC_03586 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NNGKNKDC_03587 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNGKNKDC_03588 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NNGKNKDC_03589 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NNGKNKDC_03590 3.34e-80 yqfX - - S - - - membrane
NNGKNKDC_03591 5.64e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NNGKNKDC_03592 1.46e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
NNGKNKDC_03593 5.13e-166 yqgB - - S - - - Protein of unknown function (DUF1189)
NNGKNKDC_03594 2.76e-99 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NNGKNKDC_03595 3.47e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NNGKNKDC_03596 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NNGKNKDC_03597 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NNGKNKDC_03598 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NNGKNKDC_03599 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NNGKNKDC_03600 1.68e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NNGKNKDC_03601 1.13e-183 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNGKNKDC_03602 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNGKNKDC_03603 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNGKNKDC_03604 3.42e-68 yqzD - - - - - - -
NNGKNKDC_03605 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNGKNKDC_03606 1.49e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNGKNKDC_03607 5.38e-11 yqgO - - - - - - -
NNGKNKDC_03608 1.71e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NNGKNKDC_03609 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
NNGKNKDC_03610 1.23e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NNGKNKDC_03611 6.62e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NNGKNKDC_03612 1.73e-252 yqgU - - - - - - -
NNGKNKDC_03613 2.99e-65 dglA - - S - - - Thiamine-binding protein
NNGKNKDC_03614 3.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
NNGKNKDC_03615 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NNGKNKDC_03616 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NNGKNKDC_03617 2.72e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NNGKNKDC_03619 2.49e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNGKNKDC_03620 1.53e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNGKNKDC_03621 2.62e-238 yqxL - - P - - - Mg2 transporter protein
NNGKNKDC_03622 4.48e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NNGKNKDC_03623 9.79e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NNGKNKDC_03624 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NNGKNKDC_03625 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
NNGKNKDC_03626 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NNGKNKDC_03627 6.52e-100 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NNGKNKDC_03628 1.92e-80 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NNGKNKDC_03629 2e-36 yqzE - - S - - - YqzE-like protein
NNGKNKDC_03630 5.66e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
NNGKNKDC_03631 1.56e-154 yqxM - - - ko:K19433 - ko00000 -
NNGKNKDC_03632 1.09e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NNGKNKDC_03633 7.4e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NNGKNKDC_03634 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NNGKNKDC_03635 9.44e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NNGKNKDC_03636 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
NNGKNKDC_03637 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNGKNKDC_03638 2e-265 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NNGKNKDC_03639 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNGKNKDC_03640 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNGKNKDC_03641 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NNGKNKDC_03642 1.3e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NNGKNKDC_03643 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NNGKNKDC_03644 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NNGKNKDC_03645 3.12e-82 yqhP - - - - - - -
NNGKNKDC_03646 1.42e-218 yqhQ - - S - - - Protein of unknown function (DUF1385)
NNGKNKDC_03647 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
NNGKNKDC_03648 1.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NNGKNKDC_03649 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNGKNKDC_03650 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NNGKNKDC_03651 5.39e-222 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NNGKNKDC_03652 2.32e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NNGKNKDC_03653 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NNGKNKDC_03654 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NNGKNKDC_03655 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NNGKNKDC_03656 3.01e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NNGKNKDC_03657 7.03e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NNGKNKDC_03658 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NNGKNKDC_03659 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNGKNKDC_03660 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NNGKNKDC_03661 1.36e-87 yqhY - - S - - - protein conserved in bacteria
NNGKNKDC_03662 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNGKNKDC_03663 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNGKNKDC_03664 1.43e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNGKNKDC_03665 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNGKNKDC_03666 3.17e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNGKNKDC_03667 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNGKNKDC_03668 1.19e-196 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NNGKNKDC_03669 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNGKNKDC_03670 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNGKNKDC_03671 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NNGKNKDC_03672 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NNGKNKDC_03673 1.44e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNGKNKDC_03676 2.28e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NNGKNKDC_03678 0.0 yfiU - - EGP - - - the major facilitator superfamily
NNGKNKDC_03679 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NNGKNKDC_03680 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NNGKNKDC_03681 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NNGKNKDC_03682 1.65e-230 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NNGKNKDC_03683 7.28e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNGKNKDC_03684 9.33e-125 padR - - K - - - transcriptional
NNGKNKDC_03685 1.03e-214 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNGKNKDC_03686 9.66e-243 - - - S - - - Oxidoreductase
NNGKNKDC_03687 2.65e-200 - - - G - - - Xylose isomerase
NNGKNKDC_03688 2.16e-241 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNGKNKDC_03689 3.37e-124 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
NNGKNKDC_03690 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NNGKNKDC_03691 5.54e-82 yfiD3 - - S - - - DoxX
NNGKNKDC_03692 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNGKNKDC_03693 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNGKNKDC_03694 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
NNGKNKDC_03695 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_03696 7.72e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NNGKNKDC_03697 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNGKNKDC_03698 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NNGKNKDC_03699 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NNGKNKDC_03700 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNGKNKDC_03701 2.67e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNGKNKDC_03702 6.2e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNGKNKDC_03703 1.86e-242 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNGKNKDC_03704 6.4e-115 yfjM - - S - - - Psort location Cytoplasmic, score
NNGKNKDC_03705 2.85e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNGKNKDC_03706 1.71e-64 - - - S - - - YfzA-like protein
NNGKNKDC_03707 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNGKNKDC_03708 2.85e-207 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NNGKNKDC_03709 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NNGKNKDC_03711 1.54e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NNGKNKDC_03712 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NNGKNKDC_03713 7.99e-37 yfjT - - - - - - -
NNGKNKDC_03714 1.14e-279 yfkA - - S - - - YfkB-like domain
NNGKNKDC_03715 8.63e-188 yfkC - - M - - - Mechanosensitive ion channel
NNGKNKDC_03716 6.61e-185 yfkD - - S - - - YfkD-like protein
NNGKNKDC_03717 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NNGKNKDC_03718 5.89e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03719 1.37e-12 - - - - - - - -
NNGKNKDC_03720 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NNGKNKDC_03721 3.7e-70 yfkI - - S - - - gas vesicle protein
NNGKNKDC_03722 1.39e-111 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNGKNKDC_03723 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
NNGKNKDC_03724 2.84e-251 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03725 2.89e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNGKNKDC_03726 7.14e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNGKNKDC_03727 1.58e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNGKNKDC_03728 6.43e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NNGKNKDC_03729 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NNGKNKDC_03730 4.45e-255 yibE - - S - - - YibE/F-like protein
NNGKNKDC_03731 9.94e-166 yibF - - S - - - YibE/F-like protein
NNGKNKDC_03732 2.41e-157 frp - - C - - - nitroreductase
NNGKNKDC_03733 1.67e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NNGKNKDC_03734 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNGKNKDC_03735 3.86e-314 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNGKNKDC_03736 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
NNGKNKDC_03737 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
NNGKNKDC_03738 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNGKNKDC_03739 2.43e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NNGKNKDC_03740 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NNGKNKDC_03741 9.99e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NNGKNKDC_03742 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NNGKNKDC_03743 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NNGKNKDC_03744 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
NNGKNKDC_03745 5.69e-26 yflI - - - - - - -
NNGKNKDC_03746 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
NNGKNKDC_03747 2.06e-157 yflK - - S - - - protein conserved in bacteria
NNGKNKDC_03748 4.77e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NNGKNKDC_03749 1.23e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NNGKNKDC_03750 4.87e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNGKNKDC_03751 8.19e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NNGKNKDC_03752 9.72e-227 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NNGKNKDC_03753 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNGKNKDC_03754 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNGKNKDC_03756 7.54e-07 - - - S - - - domain, Protein
NNGKNKDC_03759 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NNGKNKDC_03760 6.51e-308 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NNGKNKDC_03761 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
NNGKNKDC_03762 2.1e-31 - - - S - - - Protein of unknown function (DUF3212)
NNGKNKDC_03763 1.64e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NNGKNKDC_03764 4.11e-66 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NNGKNKDC_03765 7.57e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NNGKNKDC_03766 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNGKNKDC_03767 2.41e-262 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NNGKNKDC_03768 2.05e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NNGKNKDC_03769 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNGKNKDC_03770 2.43e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NNGKNKDC_03771 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNGKNKDC_03772 2.85e-169 yfmS - - NT - - - chemotaxis protein
NNGKNKDC_03773 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNGKNKDC_03774 1.14e-310 yfnA - - E ko:K03294 - ko00000 amino acid
NNGKNKDC_03775 1.05e-275 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNGKNKDC_03776 8.13e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NNGKNKDC_03777 1.78e-285 yfnE - - S - - - Glycosyltransferase like family 2
NNGKNKDC_03778 1.33e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NNGKNKDC_03779 1.6e-218 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NNGKNKDC_03780 4.17e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NNGKNKDC_03781 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NNGKNKDC_03783 5.02e-188 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
NNGKNKDC_03784 1.96e-145 - - - S - - - CAAX protease self-immunity
NNGKNKDC_03785 3.05e-193 - - - C - - - Nitroreductase family
NNGKNKDC_03786 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
NNGKNKDC_03787 6.23e-244 - - - S - - - ATP diphosphatase activity
NNGKNKDC_03788 9.39e-166 - - - - - - - -
NNGKNKDC_03789 6.46e-128 - - - S - - - protein homooligomerization
NNGKNKDC_03790 2.17e-161 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNGKNKDC_03791 5.11e-210 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NNGKNKDC_03792 5.83e-67 - - - K - - - Winged helix DNA-binding domain
NNGKNKDC_03794 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NNGKNKDC_03795 4.61e-250 yetN - - S - - - Protein of unknown function (DUF3900)
NNGKNKDC_03796 1.21e-264 yetM - - CH - - - FAD binding domain
NNGKNKDC_03797 8.47e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNGKNKDC_03799 1.27e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NNGKNKDC_03800 1.82e-73 - - - H - - - riboflavin kinase activity
NNGKNKDC_03801 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
NNGKNKDC_03802 7.64e-198 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNGKNKDC_03803 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNGKNKDC_03804 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NNGKNKDC_03805 8.99e-157 yetF - - S - - - membrane
NNGKNKDC_03806 5.92e-05 - - - - - - - -
NNGKNKDC_03807 1.02e-125 yesJ - - K - - - Acetyltransferase (GNAT) family
NNGKNKDC_03808 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NNGKNKDC_03809 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NNGKNKDC_03810 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NNGKNKDC_03811 1.13e-137 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NNGKNKDC_03813 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
NNGKNKDC_03814 5.59e-309 - - - S - - - Bacterial EndoU nuclease
NNGKNKDC_03815 1.59e-28 - - - S - - - Colicin immunity protein / pyocin immunity protein
NNGKNKDC_03816 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NNGKNKDC_03817 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNGKNKDC_03818 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NNGKNKDC_03819 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNGKNKDC_03820 4.24e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNGKNKDC_03821 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NNGKNKDC_03822 1.57e-197 yerO - - K - - - Transcriptional regulator
NNGKNKDC_03823 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNGKNKDC_03824 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNGKNKDC_03825 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNGKNKDC_03826 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNGKNKDC_03827 1.44e-158 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)