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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NLADLHMP_00001	7.01e-248	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NLADLHMP_00002	8.2e-235	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NLADLHMP_00004	7.86e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
NLADLHMP_00005	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NLADLHMP_00006	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NLADLHMP_00007	3.21e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NLADLHMP_00008	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NLADLHMP_00009	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NLADLHMP_00010	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NLADLHMP_00011	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
NLADLHMP_00012	2.29e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NLADLHMP_00013	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
NLADLHMP_00014	7.76e-115	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NLADLHMP_00015	7.5e-279	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NLADLHMP_00016	1.13e-278	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NLADLHMP_00017	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NLADLHMP_00018	1.07e-236	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NLADLHMP_00019	5.59e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NLADLHMP_00020	1.13e-243	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NLADLHMP_00021	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NLADLHMP_00022	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
NLADLHMP_00023	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NLADLHMP_00024	8.21e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NLADLHMP_00025	9.06e-152	ytbE	-	-	S	-	-	-	reductase
NLADLHMP_00026	2.15e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLADLHMP_00028	2.15e-235	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLADLHMP_00029	7.78e-53	-	-	-	S	-	-	-	ASCH
NLADLHMP_00030	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
NLADLHMP_00031	6.04e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NLADLHMP_00032	4.57e-32	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NLADLHMP_00033	4.61e-63	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NLADLHMP_00034	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLADLHMP_00035	1.17e-74	-	-	-	-	-	-	-	-
NLADLHMP_00036	5.27e-75	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
NLADLHMP_00037	3.76e-172	-	-	-	S	-	-	-	interspecies interaction between organisms
NLADLHMP_00038	2.51e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLADLHMP_00039	1.08e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLADLHMP_00040	1.08e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLADLHMP_00041	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLADLHMP_00042	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NLADLHMP_00044	4e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NLADLHMP_00045	4.07e-213	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NLADLHMP_00046	2.2e-271	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NLADLHMP_00048	6.86e-100	-	-	-	F	-	-	-	Phosphorylase superfamily
NLADLHMP_00049	1.82e-33	-	-	-	-	-	-	-	-
NLADLHMP_00050	5.54e-139	dkgB	-	-	S	-	-	-	reductase
NLADLHMP_00052	4.52e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLADLHMP_00053	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLADLHMP_00054	4.56e-256	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLADLHMP_00055	1.36e-71	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NLADLHMP_00056	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NLADLHMP_00057	2.59e-183	-	5.1.1.4	-	E	ko:K01777	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Proline racemase
NLADLHMP_00058	6.97e-87	-	-	-	EJ	-	-	-	Glycine/sarcosine/betaine reductase component B subunits
NLADLHMP_00059	8.38e-92	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
NLADLHMP_00060	2.69e-42	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
NLADLHMP_00061	1.14e-84	prdB	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a premature stop
NLADLHMP_00062	5.49e-35	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NLADLHMP_00063	4.14e-292	prdA	1.21.4.1	-	EJ	ko:K10793	ko00330,map00330	ko00000,ko00001,ko01000	Glycine/sarcosine/betaine reductase component B subunits
NLADLHMP_00066	3.5e-146	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NLADLHMP_00067	4.82e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
NLADLHMP_00068	3.15e-187	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLADLHMP_00069	4.32e-113	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLADLHMP_00070	1.56e-170	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLADLHMP_00071	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLADLHMP_00073	3.13e-105	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
NLADLHMP_00074	1.13e-103	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
NLADLHMP_00075	3.28e-67	-	-	-	-	-	-	-	-
NLADLHMP_00076	7.57e-80	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NLADLHMP_00077	1.25e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NLADLHMP_00078	9.57e-163	-	-	-	C	-	-	-	Oxidoreductase
NLADLHMP_00079	1.42e-13	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
NLADLHMP_00080	5.63e-224	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NLADLHMP_00081	1.29e-90	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NLADLHMP_00082	2.73e-205	spoVK	-	-	O	-	-	-	stage V sporulation protein K
NLADLHMP_00083	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NLADLHMP_00084	5.7e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NLADLHMP_00085	6.23e-164	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NLADLHMP_00086	2.28e-311	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NLADLHMP_00087	3.58e-59	-	-	-	S	-	-	-	Plasmid replication protein
NLADLHMP_00089	6.73e-272	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NLADLHMP_00090	2.84e-95	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
NLADLHMP_00091	1.96e-253	-	-	-	L	-	-	-	Transposase DDE domain group 1
NLADLHMP_00092	4.03e-86	-	-	-	-	-	-	-	-
NLADLHMP_00093	1.28e-228	-	-	-	L	-	-	-	Transposase DDE domain group 1
NLADLHMP_00094	7.67e-139	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
NLADLHMP_00095	3.78e-84	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
NLADLHMP_00096	1.66e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NLADLHMP_00097	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NLADLHMP_00098	1.64e-232	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NLADLHMP_00100	7.24e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NLADLHMP_00101	5.06e-242	-	-	-	C	-	-	-	FMN_bind
NLADLHMP_00102	2.26e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_00103	1.48e-202	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NLADLHMP_00104	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NLADLHMP_00105	7.08e-136	yueF	-	-	S	-	-	-	AI-2E family transporter
NLADLHMP_00106	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NLADLHMP_00107	6.36e-58	-	-	-	D	-	-	-	Peptidase family M23
NLADLHMP_00109	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NLADLHMP_00111	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLADLHMP_00112	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NLADLHMP_00113	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NLADLHMP_00114	1.66e-230	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLADLHMP_00115	4.14e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLADLHMP_00116	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NLADLHMP_00117	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLADLHMP_00118	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NLADLHMP_00119	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLADLHMP_00120	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLADLHMP_00121	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLADLHMP_00122	5.61e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NLADLHMP_00123	1.32e-217	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NLADLHMP_00124	4.14e-151	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
NLADLHMP_00125	7.25e-234	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NLADLHMP_00126	4.74e-48	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NLADLHMP_00127	6.11e-51	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLADLHMP_00128	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLADLHMP_00129	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLADLHMP_00130	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLADLHMP_00131	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NLADLHMP_00132	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLADLHMP_00133	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NLADLHMP_00134	1.65e-83	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
NLADLHMP_00135	4.36e-38	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NLADLHMP_00136	7.25e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NLADLHMP_00137	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLADLHMP_00140	3.72e-166	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
NLADLHMP_00141	3.22e-21	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NLADLHMP_00142	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NLADLHMP_00143	1.37e-53	-	-	-	-	-	-	-	-
NLADLHMP_00144	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLADLHMP_00145	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLADLHMP_00146	1.65e-166	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLADLHMP_00147	1.95e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NLADLHMP_00148	9.3e-211	yclK	-	-	T	-	-	-	Histidine kinase
NLADLHMP_00149	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
NLADLHMP_00150	7.89e-279	pepF	-	-	E	-	-	-	Oligopeptidase F
NLADLHMP_00151	5.02e-138	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NLADLHMP_00152	2.01e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NLADLHMP_00153	1.44e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NLADLHMP_00154	8.38e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NLADLHMP_00155	3.08e-204	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NLADLHMP_00156	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NLADLHMP_00157	9.06e-52	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLADLHMP_00158	1.24e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NLADLHMP_00159	2.84e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NLADLHMP_00160	2.82e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NLADLHMP_00161	2.88e-50	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NLADLHMP_00162	4.71e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NLADLHMP_00163	1.31e-90	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NLADLHMP_00164	2.69e-116	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NLADLHMP_00166	2.99e-65	-	-	-	S	-	-	-	VRR_NUC
NLADLHMP_00167	3.98e-148	-	-	-	-	-	-	-	-
NLADLHMP_00168	3.01e-43	-	-	-	-	-	-	-	-
NLADLHMP_00169	7.02e-153	-	-	-	K	-	-	-	DNA binding
NLADLHMP_00170	7.63e-222	fusA1	-	-	J	-	-	-	elongation factor G
NLADLHMP_00171	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NLADLHMP_00172	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NLADLHMP_00173	1.07e-125	yycH	-	-	S	-	-	-	YycH protein
NLADLHMP_00174	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
NLADLHMP_00175	1.37e-40	-	-	-	S	-	-	-	YjbR
NLADLHMP_00176	2.94e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NLADLHMP_00177	5.22e-186	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NLADLHMP_00178	2.26e-93	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLADLHMP_00179	2.25e-259	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
NLADLHMP_00180	1.34e-113	-	-	-	S	-	-	-	Acyltransferase family
NLADLHMP_00182	1.2e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NLADLHMP_00185	5.39e-43	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NLADLHMP_00186	5.49e-218	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NLADLHMP_00187	1.71e-131	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NLADLHMP_00188	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLADLHMP_00189	3.26e-106	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLADLHMP_00190	1.78e-21	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
NLADLHMP_00191	2.71e-128	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
NLADLHMP_00192	3.52e-44	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
NLADLHMP_00193	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NLADLHMP_00194	1.13e-248	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NLADLHMP_00195	2.97e-266	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NLADLHMP_00196	2.88e-53	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NLADLHMP_00197	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NLADLHMP_00198	1.55e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NLADLHMP_00199	3.83e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NLADLHMP_00200	2.29e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NLADLHMP_00201	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NLADLHMP_00203	1.53e-113	-	-	-	-	-	-	-	-
NLADLHMP_00204	1.29e-72	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLADLHMP_00205	6.95e-87	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NLADLHMP_00206	3.65e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00207	3.37e-84	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NLADLHMP_00208	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NLADLHMP_00209	4.77e-184	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NLADLHMP_00210	1.38e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NLADLHMP_00211	5.44e-130	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLADLHMP_00212	9.06e-233	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NLADLHMP_00213	2.28e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NLADLHMP_00216	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NLADLHMP_00217	3.87e-93	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NLADLHMP_00218	4.55e-20	-	-	-	-	-	-	-	-
NLADLHMP_00219	4.5e-149	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
NLADLHMP_00221	3.08e-54	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
NLADLHMP_00230	4.79e-53	-	-	-	L	-	-	-	DnaD domain protein
NLADLHMP_00233	2.16e-10	-	-	-	-	-	-	-	-
NLADLHMP_00234	1.05e-96	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLADLHMP_00235	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
NLADLHMP_00236	4.73e-119	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NLADLHMP_00237	6.87e-90	-	-	-	-	-	-	-	-
NLADLHMP_00239	1.21e-20	-	-	-	-	-	-	-	-
NLADLHMP_00240	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NLADLHMP_00241	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NLADLHMP_00242	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NLADLHMP_00243	6.59e-219	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NLADLHMP_00244	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NLADLHMP_00245	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NLADLHMP_00246	1.4e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NLADLHMP_00247	2.16e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NLADLHMP_00248	3.63e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
NLADLHMP_00249	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NLADLHMP_00250	6.79e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NLADLHMP_00252	5.69e-142	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NLADLHMP_00253	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NLADLHMP_00254	2.17e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NLADLHMP_00255	5.32e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NLADLHMP_00256	5.94e-253	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NLADLHMP_00257	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NLADLHMP_00258	3.24e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLADLHMP_00259	3.54e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NLADLHMP_00260	3.83e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NLADLHMP_00263	7.52e-100	-	-	-	L	-	-	-	Replication protein
NLADLHMP_00264	0.000187	-	-	-	-	-	-	-	-
NLADLHMP_00266	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLADLHMP_00267	7.59e-279	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00269	5.59e-83	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
NLADLHMP_00270	5.49e-230	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NLADLHMP_00271	4.62e-62	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
NLADLHMP_00272	2.48e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NLADLHMP_00273	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLADLHMP_00274	7.67e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NLADLHMP_00275	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLADLHMP_00276	1.53e-165	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLADLHMP_00277	3.41e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLADLHMP_00278	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NLADLHMP_00279	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NLADLHMP_00280	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLADLHMP_00281	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NLADLHMP_00282	2.69e-179	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLADLHMP_00283	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLADLHMP_00284	6.16e-237	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLADLHMP_00285	5.97e-166	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLADLHMP_00286	2.88e-146	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
NLADLHMP_00288	3.67e-110	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NLADLHMP_00289	1.27e-47	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NLADLHMP_00290	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NLADLHMP_00291	2.1e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NLADLHMP_00292	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NLADLHMP_00293	2.11e-131	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NLADLHMP_00294	5.11e-112	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NLADLHMP_00295	9.23e-36	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
NLADLHMP_00296	1.09e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NLADLHMP_00298	7.81e-193	-	-	-	EGP	-	-	-	Major Facilitator
NLADLHMP_00299	2.95e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NLADLHMP_00300	2.62e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NLADLHMP_00301	4.74e-45	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NLADLHMP_00302	2.97e-132	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NLADLHMP_00303	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLADLHMP_00304	8.87e-168	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLADLHMP_00305	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NLADLHMP_00306	3.68e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NLADLHMP_00307	9.5e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NLADLHMP_00308	7.22e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NLADLHMP_00309	5.06e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLADLHMP_00310	5.01e-22	yneR	-	-	-	-	-	-	-
NLADLHMP_00311	2.41e-75	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLADLHMP_00312	4.16e-259	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLADLHMP_00313	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
NLADLHMP_00314	2.01e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NLADLHMP_00315	1.03e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NLADLHMP_00316	2.27e-173	-	-	-	V	-	-	-	MatE
NLADLHMP_00317	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLADLHMP_00318	5.52e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
NLADLHMP_00319	5.27e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLADLHMP_00320	5.23e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLADLHMP_00321	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NLADLHMP_00322	1.22e-128	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NLADLHMP_00323	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
NLADLHMP_00324	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
NLADLHMP_00326	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLADLHMP_00327	2.77e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLADLHMP_00328	1.09e-78	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLADLHMP_00329	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NLADLHMP_00330	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLADLHMP_00331	5.73e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
NLADLHMP_00332	8.77e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NLADLHMP_00334	1.91e-08	vpr	3.4.21.96	-	DO	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	PA domain
NLADLHMP_00336	1.48e-284	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NLADLHMP_00337	6.86e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NLADLHMP_00338	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
NLADLHMP_00339	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NLADLHMP_00340	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLADLHMP_00341	3.88e-160	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NLADLHMP_00342	9.98e-93	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NLADLHMP_00343	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NLADLHMP_00344	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
NLADLHMP_00345	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NLADLHMP_00346	2.6e-230	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NLADLHMP_00347	5.42e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NLADLHMP_00348	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLADLHMP_00349	4.13e-94	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NLADLHMP_00350	9.92e-288	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLADLHMP_00351	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLADLHMP_00352	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NLADLHMP_00353	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLADLHMP_00354	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLADLHMP_00355	2.13e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLADLHMP_00356	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NLADLHMP_00357	1.57e-77	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NLADLHMP_00358	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NLADLHMP_00359	9.52e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NLADLHMP_00360	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NLADLHMP_00361	6.36e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLADLHMP_00362	6.13e-212	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NLADLHMP_00363	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NLADLHMP_00366	1.28e-80	-	-	-	-	-	-	-	-
NLADLHMP_00375	7.02e-90	-	-	-	-	-	-	-	-
NLADLHMP_00376	4.18e-28	-	-	-	-	-	-	-	-
NLADLHMP_00379	1.81e-26	-	-	-	S	-	-	-	N-terminal phage replisome organiser (Phage_rep_org_N)
NLADLHMP_00380	9.24e-68	-	-	-	S	-	-	-	Putative HNHc nuclease
NLADLHMP_00386	3.01e-93	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
NLADLHMP_00387	6.22e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NLADLHMP_00388	3.29e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLADLHMP_00389	2.28e-283	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLADLHMP_00390	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLADLHMP_00391	1.44e-179	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLADLHMP_00393	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NLADLHMP_00394	5.81e-42	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NLADLHMP_00395	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NLADLHMP_00396	1.68e-96	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NLADLHMP_00397	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NLADLHMP_00398	2.02e-51	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NLADLHMP_00399	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NLADLHMP_00400	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NLADLHMP_00401	1.04e-202	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NLADLHMP_00402	6.43e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NLADLHMP_00403	3.91e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NLADLHMP_00404	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
NLADLHMP_00405	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLADLHMP_00406	2.13e-118	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NLADLHMP_00407	1.21e-145	vanR	-	-	K	-	-	-	response regulator
NLADLHMP_00408	7.86e-106	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NLADLHMP_00409	4.67e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NLADLHMP_00410	1.82e-206	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLADLHMP_00411	4.78e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLADLHMP_00412	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
NLADLHMP_00413	1.13e-59	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLADLHMP_00414	2e-171	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NLADLHMP_00415	2.24e-05	-	-	-	-	-	-	-	-
NLADLHMP_00420	1.13e-22	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NLADLHMP_00421	1.19e-96	-	-	-	S	ko:K06919	-	ko00000	DNA primase
NLADLHMP_00423	1.1e-277	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLADLHMP_00424	2.38e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NLADLHMP_00425	7.2e-94	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NLADLHMP_00427	1.36e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
NLADLHMP_00428	2.11e-156	-	-	-	S	-	-	-	Phage tail tube protein
NLADLHMP_00429	1.77e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
NLADLHMP_00430	2.78e-85	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NLADLHMP_00431	2.22e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
NLADLHMP_00432	3.09e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NLADLHMP_00433	3.71e-280	-	-	-	S	-	-	-	Phage capsid family
NLADLHMP_00434	1.04e-152	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NLADLHMP_00435	2.26e-68	-	-	-	S	-	-	-	Phage portal protein
NLADLHMP_00437	3.59e-60	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NLADLHMP_00438	7.92e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLADLHMP_00439	3.7e-24	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLADLHMP_00440	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
NLADLHMP_00441	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLADLHMP_00442	3.71e-37	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NLADLHMP_00443	1.53e-163	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NLADLHMP_00444	1.17e-23	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NLADLHMP_00445	3.47e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLADLHMP_00446	1.18e-160	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLADLHMP_00447	7.93e-152	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
NLADLHMP_00448	2.46e-11	-	-	-	-	-	-	-	-
NLADLHMP_00449	9.96e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00450	6.87e-126	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NLADLHMP_00451	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NLADLHMP_00452	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NLADLHMP_00453	1.17e-239	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NLADLHMP_00454	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NLADLHMP_00455	1.68e-187	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NLADLHMP_00456	3.27e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NLADLHMP_00457	1.28e-88	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
NLADLHMP_00458	1.01e-110	-	-	-	S	-	-	-	hydrolase
NLADLHMP_00459	2.43e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NLADLHMP_00460	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLADLHMP_00461	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLADLHMP_00462	7.47e-152	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLADLHMP_00463	2.13e-103	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
NLADLHMP_00464	3.98e-116	yeeC	-	-	P	-	-	-	T5orf172
NLADLHMP_00465	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
NLADLHMP_00466	1.4e-76	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NLADLHMP_00468	1.12e-15	-	-	-	M	-	-	-	Lysin motif
NLADLHMP_00469	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NLADLHMP_00470	1.98e-43	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NLADLHMP_00471	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLADLHMP_00472	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NLADLHMP_00473	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
NLADLHMP_00474	1.01e-117	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NLADLHMP_00475	1.23e-27	-	-	-	-	-	-	-	-
NLADLHMP_00476	6.46e-75	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
NLADLHMP_00477	1.65e-24	-	-	-	-	-	-	-	-
NLADLHMP_00478	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NLADLHMP_00479	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
NLADLHMP_00480	3.58e-132	-	-	-	E	-	-	-	AzlC protein
NLADLHMP_00481	1.81e-24	-	-	-	-	-	-	-	-
NLADLHMP_00482	7.25e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NLADLHMP_00483	1.17e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NLADLHMP_00484	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
NLADLHMP_00485	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLADLHMP_00486	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLADLHMP_00487	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NLADLHMP_00488	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLADLHMP_00489	1.27e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLADLHMP_00490	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NLADLHMP_00491	1.51e-75	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NLADLHMP_00492	2.57e-76	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NLADLHMP_00493	1.32e-204	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLADLHMP_00494	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NLADLHMP_00495	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLADLHMP_00496	2.56e-32	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NLADLHMP_00497	4.14e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NLADLHMP_00498	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NLADLHMP_00499	8.74e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NLADLHMP_00500	1.32e-31	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NLADLHMP_00501	9.57e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
NLADLHMP_00502	4.25e-92	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NLADLHMP_00503	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NLADLHMP_00504	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLADLHMP_00505	9.95e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLADLHMP_00506	5.55e-126	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NLADLHMP_00507	5.19e-205	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NLADLHMP_00508	3.15e-127	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
NLADLHMP_00509	1.46e-141	csrR	-	-	K	-	-	-	response regulator
NLADLHMP_00510	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NLADLHMP_00511	1.49e-193	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NLADLHMP_00512	5.08e-241	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NLADLHMP_00513	4.45e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLADLHMP_00514	1.01e-77	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NLADLHMP_00515	9.88e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NLADLHMP_00516	1.09e-243	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NLADLHMP_00517	1.02e-18	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NLADLHMP_00518	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NLADLHMP_00519	1.29e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NLADLHMP_00520	7.25e-214	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NLADLHMP_00521	1.63e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLADLHMP_00522	2.57e-135	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NLADLHMP_00523	4.6e-142	-	-	-	L	-	-	-	Initiator Replication protein
NLADLHMP_00524	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NLADLHMP_00525	6.44e-34	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NLADLHMP_00526	5.56e-32	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
NLADLHMP_00527	4.16e-118	-	-	-	C	-	-	-	Luciferase-like monooxygenase
NLADLHMP_00532	1.36e-207	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NLADLHMP_00533	9.01e-57	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Pts system
NLADLHMP_00534	7.59e-88	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NLADLHMP_00535	4.77e-72	-	-	-	-	-	-	-	-
NLADLHMP_00537	1.91e-73	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NLADLHMP_00538	2.25e-34	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLADLHMP_00539	1.56e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NLADLHMP_00540	3.63e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NLADLHMP_00541	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NLADLHMP_00542	8.18e-273	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NLADLHMP_00543	5.22e-255	-	-	-	L	-	-	-	transposition, DNA-mediated
NLADLHMP_00544	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NLADLHMP_00546	1.18e-295	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLADLHMP_00547	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NLADLHMP_00549	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLADLHMP_00550	2.59e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLADLHMP_00551	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NLADLHMP_00552	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLADLHMP_00553	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NLADLHMP_00554	7.4e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NLADLHMP_00555	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NLADLHMP_00556	3.42e-270	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NLADLHMP_00557	8.49e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLADLHMP_00558	7.95e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLADLHMP_00559	1.27e-180	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
NLADLHMP_00560	1.47e-135	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLADLHMP_00561	4.48e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLADLHMP_00562	1.91e-187	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NLADLHMP_00563	0.0	-	-	-	L	-	-	-	Transposase DDE domain group 1
NLADLHMP_00564	9.45e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	purine ribonucleoside salvage
NLADLHMP_00565	6.77e-215	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	adenylyltransferase
NLADLHMP_00566	4.01e-181	-	-	-	Q	-	-	-	Protein of unknown function (DUF1698)
NLADLHMP_00567	1.26e-211	-	-	-	L	-	-	-	Nucleotidyltransferase domain
NLADLHMP_00568	2.77e-45	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NLADLHMP_00569	0.0	-	-	-	L	-	-	-	Recombinase
NLADLHMP_00570	1.91e-93	-	-	-	S	-	-	-	Recombinase
NLADLHMP_00571	7.01e-109	-	-	-	L	-	-	-	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NLADLHMP_00575	1.59e-75	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NLADLHMP_00576	5.09e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NLADLHMP_00577	8.17e-96	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NLADLHMP_00578	6.41e-152	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NLADLHMP_00579	7.15e-72	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLADLHMP_00580	1.93e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLADLHMP_00581	5.8e-143	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00582	6.74e-141	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLADLHMP_00583	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLADLHMP_00584	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLADLHMP_00585	2.99e-266	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLADLHMP_00586	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLADLHMP_00587	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLADLHMP_00588	2.29e-186	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NLADLHMP_00589	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NLADLHMP_00590	2.59e-309	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLADLHMP_00591	3.13e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLADLHMP_00592	2.45e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NLADLHMP_00593	5.89e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
NLADLHMP_00594	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NLADLHMP_00595	1.44e-150	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NLADLHMP_00596	5.7e-146	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLADLHMP_00597	1.48e-129	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLADLHMP_00598	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NLADLHMP_00599	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NLADLHMP_00600	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NLADLHMP_00601	3.91e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NLADLHMP_00602	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NLADLHMP_00603	5.21e-269	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NLADLHMP_00604	9.33e-186	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NLADLHMP_00605	1.74e-313	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NLADLHMP_00606	5.57e-268	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NLADLHMP_00607	8.51e-170	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NLADLHMP_00609	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NLADLHMP_00610	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NLADLHMP_00611	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
NLADLHMP_00612	4.97e-140	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLADLHMP_00613	3.58e-23	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NLADLHMP_00614	2.84e-107	-	-	-	C	-	-	-	nitroreductase
NLADLHMP_00615	4.37e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
NLADLHMP_00616	2.34e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NLADLHMP_00617	1.29e-215	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLADLHMP_00618	4.24e-314	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
NLADLHMP_00619	3.48e-105	-	-	-	-	-	-	-	-
NLADLHMP_00620	7.02e-09	-	-	-	S	-	-	-	YSIRK type signal peptide
NLADLHMP_00623	8.74e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLADLHMP_00624	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NLADLHMP_00625	3.32e-13	selB	-	-	J	ko:K03833	-	ko00000,ko03012	Elongation factor SelB, winged helix
NLADLHMP_00626	1.19e-138	-	-	-	E	-	-	-	Serine hydroxymethyltransferase
NLADLHMP_00627	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLADLHMP_00628	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLADLHMP_00630	0.000904	-	-	-	S	-	-	-	zinc-ribbon domain
NLADLHMP_00631	3.79e-254	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLADLHMP_00634	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLADLHMP_00635	8.08e-58	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLADLHMP_00636	2.84e-20	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NLADLHMP_00637	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLADLHMP_00638	7.65e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NLADLHMP_00639	4.93e-217	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLADLHMP_00641	0.0	-	-	-	S	-	-	-	Phage Terminase
NLADLHMP_00642	1.05e-107	-	-	-	L	-	-	-	Phage terminase, small subunit
NLADLHMP_00643	4.73e-116	-	-	-	L	-	-	-	HNH nucleases
NLADLHMP_00646	7.48e-23	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NLADLHMP_00647	2.63e-08	-	-	-	T	-	-	-	SpoVT / AbrB like domain
NLADLHMP_00648	2.57e-42	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
NLADLHMP_00650	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
NLADLHMP_00651	1.29e-52	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NLADLHMP_00652	2.69e-176	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NLADLHMP_00653	7.72e-293	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLADLHMP_00654	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLADLHMP_00655	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NLADLHMP_00656	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NLADLHMP_00657	5.65e-160	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NLADLHMP_00658	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NLADLHMP_00659	3.47e-79	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
NLADLHMP_00660	2.86e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLADLHMP_00661	4.53e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NLADLHMP_00662	3.33e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
NLADLHMP_00663	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NLADLHMP_00664	6.69e-33	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NLADLHMP_00665	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NLADLHMP_00666	4.77e-70	-	-	-	S	-	-	-	Membrane
NLADLHMP_00667	8.38e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NLADLHMP_00669	1.52e-264	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NLADLHMP_00670	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NLADLHMP_00671	1.09e-237	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLADLHMP_00672	1.36e-78	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NLADLHMP_00673	9.32e-143	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NLADLHMP_00674	5.21e-55	-	-	-	S	-	-	-	repeat protein
NLADLHMP_00675	4.85e-128	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
NLADLHMP_00676	3.01e-57	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NLADLHMP_00677	1.18e-116	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NLADLHMP_00678	4.47e-129	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NLADLHMP_00679	2.74e-180	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NLADLHMP_00680	5.31e-278	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NLADLHMP_00681	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLADLHMP_00682	2.18e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NLADLHMP_00683	6.38e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NLADLHMP_00684	1.53e-181	-	-	-	C	-	-	-	Aldo/keto reductase family
NLADLHMP_00685	5.71e-315	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NLADLHMP_00686	1.21e-25	-	-	-	S	-	-	-	Cupredoxin-like domain
NLADLHMP_00687	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
NLADLHMP_00688	6.15e-191	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NLADLHMP_00689	9.65e-230	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
NLADLHMP_00690	2.85e-146	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
NLADLHMP_00691	2.34e-77	-	-	-	S	-	-	-	intracellular protease amidase
NLADLHMP_00692	5.47e-167	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NLADLHMP_00693	2.72e-27	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLADLHMP_00695	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NLADLHMP_00696	4.4e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NLADLHMP_00697	5.02e-263	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NLADLHMP_00698	6.24e-84	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NLADLHMP_00700	7.04e-93	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NLADLHMP_00701	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLADLHMP_00702	2.38e-209	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLADLHMP_00703	7.84e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NLADLHMP_00704	7.79e-245	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NLADLHMP_00705	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLADLHMP_00706	6.98e-215	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NLADLHMP_00707	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NLADLHMP_00708	5.26e-298	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NLADLHMP_00709	7.05e-53	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLADLHMP_00710	1.65e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NLADLHMP_00711	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NLADLHMP_00712	4.09e-261	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLADLHMP_00713	2.54e-44	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NLADLHMP_00714	7.27e-111	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NLADLHMP_00715	1.08e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLADLHMP_00716	1.91e-306	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLADLHMP_00717	1.21e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NLADLHMP_00718	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NLADLHMP_00719	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NLADLHMP_00720	3.25e-140	selA	2.9.1.1	-	J	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NLADLHMP_00721	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NLADLHMP_00722	3.27e-57	cps3F	-	-	-	-	-	-	-
NLADLHMP_00723	2.22e-108	-	-	-	S	-	-	-	Membrane
NLADLHMP_00724	0.0	-	-	-	E	-	-	-	Amino acid permease
NLADLHMP_00725	5e-63	cadA	-	-	P	-	-	-	P-type ATPase
NLADLHMP_00726	9.35e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NLADLHMP_00727	3.89e-27	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLADLHMP_00728	1.09e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLADLHMP_00729	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NLADLHMP_00730	7.68e-100	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NLADLHMP_00732	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
NLADLHMP_00733	6.67e-43	-	-	-	P	-	-	-	Heavy-metal-associated domain
NLADLHMP_00734	1.29e-200	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NLADLHMP_00735	1.06e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NLADLHMP_00736	1.75e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
NLADLHMP_00737	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
NLADLHMP_00738	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLADLHMP_00739	7.02e-157	-	-	-	K	-	-	-	LysR substrate binding domain
NLADLHMP_00741	4.26e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
NLADLHMP_00742	4.52e-115	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NLADLHMP_00743	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
NLADLHMP_00744	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLADLHMP_00745	4.12e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLADLHMP_00746	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NLADLHMP_00747	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NLADLHMP_00748	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLADLHMP_00749	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NLADLHMP_00750	2.6e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NLADLHMP_00751	0.0	ydaO	-	-	E	-	-	-	amino acid
NLADLHMP_00752	1.07e-214	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
NLADLHMP_00753	1.82e-19	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NLADLHMP_00754	3.36e-75	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NLADLHMP_00755	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NLADLHMP_00756	3.18e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NLADLHMP_00757	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NLADLHMP_00758	1.86e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
NLADLHMP_00759	4.81e-66	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLADLHMP_00760	1.07e-28	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NLADLHMP_00761	5.11e-85	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NLADLHMP_00762	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NLADLHMP_00763	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
NLADLHMP_00764	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NLADLHMP_00765	8.61e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
NLADLHMP_00779	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NLADLHMP_00780	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NLADLHMP_00781	1.24e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NLADLHMP_00782	9.78e-82	-	-	-	C	-	-	-	FMN binding
NLADLHMP_00783	2.37e-290	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLADLHMP_00785	7.33e-71	-	-	-	-	-	-	-	-
NLADLHMP_00786	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NLADLHMP_00787	9.11e-53	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NLADLHMP_00788	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NLADLHMP_00789	1.68e-69	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
NLADLHMP_00790	1.86e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NLADLHMP_00791	2.47e-185	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NLADLHMP_00792	3.67e-172	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NLADLHMP_00793	2.29e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NLADLHMP_00794	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLADLHMP_00796	6.52e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLADLHMP_00797	1.42e-75	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NLADLHMP_00798	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLADLHMP_00799	3.83e-46	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NLADLHMP_00800	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NLADLHMP_00801	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLADLHMP_00802	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NLADLHMP_00803	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLADLHMP_00804	2.76e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NLADLHMP_00805	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00806	5.82e-93	epsB	-	-	M	-	-	-	biosynthesis protein
NLADLHMP_00807	2.68e-116	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NLADLHMP_00808	5.99e-142	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NLADLHMP_00809	1.29e-161	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NLADLHMP_00810	3.98e-114	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
NLADLHMP_00811	5.49e-150	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
NLADLHMP_00813	2.05e-138	ampC	-	-	V	-	-	-	Beta-lactamase
NLADLHMP_00814	1.83e-41	-	-	-	-	-	-	-	-
NLADLHMP_00815	1.09e-21	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00816	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLADLHMP_00817	8.89e-264	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLADLHMP_00819	9.94e-58	-	-	-	S	-	-	-	zinc-ribbon domain
NLADLHMP_00820	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLADLHMP_00821	6.4e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NLADLHMP_00822	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NLADLHMP_00823	1.05e-61	-	-	-	M	-	-	-	LysM domain protein
NLADLHMP_00824	1.03e-145	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NLADLHMP_00825	1.49e-27	-	-	-	S	ko:K16710	-	ko00000	Polysaccharide pyruvyl transferase
NLADLHMP_00830	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLADLHMP_00831	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NLADLHMP_00832	9.08e-273	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NLADLHMP_00833	4.25e-153	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NLADLHMP_00834	1.38e-145	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLADLHMP_00835	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLADLHMP_00836	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NLADLHMP_00837	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLADLHMP_00838	1.13e-59	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLADLHMP_00839	9.53e-263	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLADLHMP_00840	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLADLHMP_00843	2.18e-181	-	-	-	V	-	-	-	Pfam:Methyltransf_26
NLADLHMP_00844	3.91e-287	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLADLHMP_00845	1.78e-51	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NLADLHMP_00846	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLADLHMP_00847	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLADLHMP_00848	4.15e-47	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
NLADLHMP_00849	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
NLADLHMP_00850	3.59e-143	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLADLHMP_00851	1.19e-12	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NLADLHMP_00852	3.15e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NLADLHMP_00853	2.86e-27	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLADLHMP_00854	1.5e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLADLHMP_00855	7.08e-113	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLADLHMP_00856	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NLADLHMP_00857	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NLADLHMP_00858	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NLADLHMP_00859	3.23e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLADLHMP_00860	7.04e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NLADLHMP_00861	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NLADLHMP_00862	1.6e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NLADLHMP_00863	2.31e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NLADLHMP_00864	1.49e-11	-	-	-	E	-	-	-	Amino acid permease
NLADLHMP_00865	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NLADLHMP_00866	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NLADLHMP_00867	4.37e-79	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NLADLHMP_00868	3.66e-216	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NLADLHMP_00869	5.54e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
NLADLHMP_00870	2.09e-76	-	-	-	EG	-	-	-	EamA-like transporter family
NLADLHMP_00872	1.74e-103	-	-	-	K	-	-	-	Penicillinase repressor
NLADLHMP_00873	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	haloacid dehalogenase-like hydrolase
NLADLHMP_00874	1.4e-53	-	-	-	S	ko:K08982	-	ko00000	membrane protein (DUF2078)
NLADLHMP_00875	5.25e-22	-	-	-	S	-	-	-	Domain of unknown function DUF302
NLADLHMP_00876	1.61e-44	-	-	-	S	-	-	-	Domain of unknown function DUF302
NLADLHMP_00877	4.81e-151	-	-	-	K	-	-	-	response regulator
NLADLHMP_00878	1.99e-209	hpk7	2.7.13.3	-	T	ko:K10681	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NLADLHMP_00879	2.26e-58	hpk7	2.7.13.3	-	T	ko:K10681	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NLADLHMP_00880	1.07e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NLADLHMP_00881	1.5e-216	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NLADLHMP_00888	1.06e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NLADLHMP_00889	3.63e-87	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NLADLHMP_00891	2.81e-95	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLADLHMP_00892	1.49e-17	arbY	-	-	M	-	-	-	family 8
NLADLHMP_00894	6.08e-65	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NLADLHMP_00895	2.3e-43	-	-	-	M	-	-	-	Glycosyl transferase, family 8
NLADLHMP_00896	1.2e-112	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NLADLHMP_00897	3.55e-70	-	-	-	V	-	-	-	endonuclease activity
NLADLHMP_00898	1.42e-111	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
NLADLHMP_00899	8.89e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NLADLHMP_00900	8.14e-148	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NLADLHMP_00901	1.03e-75	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NLADLHMP_00902	4.52e-286	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
NLADLHMP_00903	3.07e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00904	1.2e-193	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NLADLHMP_00905	8.21e-53	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NLADLHMP_00906	1.42e-276	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
NLADLHMP_00907	2.26e-141	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NLADLHMP_00909	1.65e-234	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NLADLHMP_00910	5.17e-80	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLADLHMP_00911	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NLADLHMP_00912	1.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NLADLHMP_00913	1.54e-223	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLADLHMP_00914	5.53e-44	-	-	-	M	-	-	-	GNAT acetyltransferase
NLADLHMP_00915	3.9e-21	-	-	-	M	-	-	-	GNAT acetyltransferase
NLADLHMP_00916	5.44e-86	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NLADLHMP_00917	8.86e-72	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NLADLHMP_00918	1.97e-102	-	-	-	F	-	-	-	Hydrolase, nudix family
NLADLHMP_00920	7.08e-170	-	-	-	M	-	-	-	Rib/alpha-like repeat
NLADLHMP_00922	1.72e-173	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NLADLHMP_00923	6.62e-58	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NLADLHMP_00924	9.38e-81	-	-	-	-	-	-	-	-
NLADLHMP_00925	4.16e-226	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NLADLHMP_00926	8.24e-53	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NLADLHMP_00927	3.04e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLADLHMP_00928	1.68e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NLADLHMP_00929	2.68e-265	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NLADLHMP_00930	4.3e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLADLHMP_00931	7.19e-189	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NLADLHMP_00932	5.94e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
NLADLHMP_00933	1.08e-39	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NLADLHMP_00934	8.11e-94	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NLADLHMP_00935	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NLADLHMP_00936	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NLADLHMP_00937	1.3e-15	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLADLHMP_00938	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NLADLHMP_00939	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLADLHMP_00940	9.96e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLADLHMP_00941	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLADLHMP_00942	5.27e-284	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLADLHMP_00943	6.02e-288	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NLADLHMP_00944	9.05e-123	-	-	-	-	-	-	-	-
NLADLHMP_00945	5.33e-17	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NLADLHMP_00946	4.97e-69	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NLADLHMP_00947	1.13e-194	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NLADLHMP_00948	5.52e-121	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NLADLHMP_00949	1.78e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NLADLHMP_00950	8.72e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NLADLHMP_00951	4.11e-93	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NLADLHMP_00952	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NLADLHMP_00953	0.0	-	-	-	S	-	-	-	membrane
NLADLHMP_00954	1.3e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
NLADLHMP_00956	2.78e-32	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NLADLHMP_00957	1.24e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NLADLHMP_00958	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLADLHMP_00959	3.09e-160	mocA	-	-	S	-	-	-	Oxidoreductase
NLADLHMP_00960	9.82e-202	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NLADLHMP_00961	2.99e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NLADLHMP_00962	2.06e-14	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NLADLHMP_00963	1.01e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLADLHMP_00964	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLADLHMP_00965	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLADLHMP_00966	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLADLHMP_00967	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLADLHMP_00970	4.09e-108	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NLADLHMP_00971	3.93e-89	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NLADLHMP_00972	1.53e-184	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NLADLHMP_00973	3.93e-190	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NLADLHMP_00974	1.61e-102	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLADLHMP_00975	3.03e-19	cvpA	-	-	S	-	-	-	Colicin V production protein
NLADLHMP_00976	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLADLHMP_00977	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NLADLHMP_00978	3.16e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLADLHMP_00979	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NLADLHMP_00980	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NLADLHMP_00981	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
NLADLHMP_00982	1.17e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NLADLHMP_00983	1.48e-73	napB	-	-	K	-	-	-	transcriptional
NLADLHMP_00984	2.88e-154	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLADLHMP_00985	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLADLHMP_00986	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NLADLHMP_00987	1.05e-76	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NLADLHMP_00988	1.22e-258	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
NLADLHMP_00989	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NLADLHMP_00990	3.51e-20	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	S-adenosylmethionine synthetase, central domain
NLADLHMP_00991	9.16e-112	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NLADLHMP_00992	1.36e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NLADLHMP_00993	1.43e-98	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLADLHMP_00994	1.13e-59	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLADLHMP_00995	4.44e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLADLHMP_00996	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NLADLHMP_00997	1.13e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NLADLHMP_00998	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_00999	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NLADLHMP_01001	4.03e-93	-	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
NLADLHMP_01003	2.52e-82	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
NLADLHMP_01004	4.23e-38	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
NLADLHMP_01005	2.84e-67	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
NLADLHMP_01007	4.45e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLADLHMP_01008	8.95e-73	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
NLADLHMP_01009	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLADLHMP_01010	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLADLHMP_01011	1.52e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLADLHMP_01012	1.6e-107	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NLADLHMP_01013	4.06e-98	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NLADLHMP_01014	2.57e-164	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NLADLHMP_01015	1.15e-82	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NLADLHMP_01016	1.66e-53	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
NLADLHMP_01017	2.92e-205	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLADLHMP_01018	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NLADLHMP_01019	7.47e-72	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NLADLHMP_01020	6.94e-28	-	-	-	-	-	-	-	-
NLADLHMP_01021	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLADLHMP_01022	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NLADLHMP_01023	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NLADLHMP_01024	7.28e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLADLHMP_01025	1.47e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NLADLHMP_01027	4.75e-112	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NLADLHMP_01028	2.24e-52	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLADLHMP_01029	5.61e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLADLHMP_01030	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLADLHMP_01031	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLADLHMP_01032	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLADLHMP_01033	1.8e-69	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NLADLHMP_01034	2.12e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
NLADLHMP_01035	2.26e-59	ykuL	-	-	S	-	-	-	CBS domain
NLADLHMP_01036	2.43e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLADLHMP_01037	2.9e-114	nanK	-	-	GK	-	-	-	ROK family
NLADLHMP_01038	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NLADLHMP_01039	3.85e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NLADLHMP_01040	9.06e-181	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NLADLHMP_01041	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NLADLHMP_01043	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLADLHMP_01044	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NLADLHMP_01045	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NLADLHMP_01047	9.35e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NLADLHMP_01048	5.14e-278	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NLADLHMP_01049	1.12e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
NLADLHMP_01050	5.1e-136	-	-	-	S	-	-	-	Fic/DOC family
NLADLHMP_01051	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NLADLHMP_01052	2.3e-88	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLADLHMP_01053	2.8e-71	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLADLHMP_01054	9e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NLADLHMP_01055	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLADLHMP_01056	2.52e-17	-	-	-	-	-	-	-	-
NLADLHMP_01057	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NLADLHMP_01058	5.37e-279	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NLADLHMP_01059	9.46e-40	-	-	-	S	-	-	-	Enterocin A Immunity
NLADLHMP_01060	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLADLHMP_01061	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NLADLHMP_01062	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLADLHMP_01063	1.72e-105	ylmH	-	-	S	-	-	-	S4 domain protein
NLADLHMP_01064	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NLADLHMP_01065	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLADLHMP_01066	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLADLHMP_01067	1.1e-241	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLADLHMP_01068	1.13e-59	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLADLHMP_01069	1.18e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NLADLHMP_01070	4.06e-62	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NLADLHMP_01071	7.72e-16	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
NLADLHMP_01073	4.53e-07	-	-	-	L	-	-	-	hmm pf01527
NLADLHMP_01075	3.86e-188	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NLADLHMP_01076	9.19e-39	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NLADLHMP_01077	1.61e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NLADLHMP_01078	1.5e-22	-	-	-	-	-	-	-	-
NLADLHMP_01079	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NLADLHMP_01080	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLADLHMP_01081	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NLADLHMP_01082	2.98e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NLADLHMP_01083	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLADLHMP_01084	4.26e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLADLHMP_01085	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NLADLHMP_01086	2.66e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLADLHMP_01087	2.38e-148	-	-	-	P	-	-	-	Rhodanese Homology Domain
NLADLHMP_01088	9.43e-23	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
NLADLHMP_01089	9.49e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLADLHMP_01090	7.97e-85	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLADLHMP_01091	9.93e-26	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLADLHMP_01092	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLADLHMP_01093	6.62e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NLADLHMP_01094	4.29e-16	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NLADLHMP_01095	1.31e-80	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NLADLHMP_01096	1.9e-159	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLADLHMP_01097	3.18e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NLADLHMP_01098	5.73e-44	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLADLHMP_01099	2.65e-35	-	-	-	-	-	-	-	-
NLADLHMP_01100	7.58e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NLADLHMP_01101	1.18e-138	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NLADLHMP_01102	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
NLADLHMP_01103	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLADLHMP_01104	7.32e-101	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLADLHMP_01105	3.11e-108	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLADLHMP_01106	2.01e-61	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NLADLHMP_01109	1.5e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLADLHMP_01110	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NLADLHMP_01111	1.24e-99	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NLADLHMP_01112	2.3e-24	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NLADLHMP_01113	1.82e-67	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NLADLHMP_01114	8.88e-14	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NLADLHMP_01115	2.75e-46	-	-	-	-	-	-	-	-
NLADLHMP_01117	3.48e-83	yxeH	-	-	S	-	-	-	hydrolase
NLADLHMP_01118	3.52e-225	XK27_08315	-	-	M	-	-	-	Sulfatase
NLADLHMP_01119	4.7e-125	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NLADLHMP_01120	3.53e-230	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NLADLHMP_01122	4.82e-29	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NLADLHMP_01124	3.61e-60	pinR	-	-	L	ko:K14060	-	ko00000	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NLADLHMP_01125	9.07e-91	-	-	-	-	-	-	-	-
NLADLHMP_01126	3.61e-56	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NLADLHMP_01128	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NLADLHMP_01129	2.21e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01130	9.69e-90	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NLADLHMP_01133	3.15e-200	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLADLHMP_01134	1.89e-75	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLADLHMP_01135	5.98e-178	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NLADLHMP_01136	1.29e-11	-	-	-	-	-	-	-	-
NLADLHMP_01137	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLADLHMP_01138	2.27e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NLADLHMP_01139	1.78e-34	-	-	-	-	-	-	-	-
NLADLHMP_01140	8.24e-99	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NLADLHMP_01141	4.69e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLADLHMP_01142	3.92e-68	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLADLHMP_01143	4.74e-130	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLADLHMP_01144	4.54e-124	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
NLADLHMP_01145	2.82e-88	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NLADLHMP_01146	1.16e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01147	1.1e-68	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NLADLHMP_01148	4.12e-125	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
NLADLHMP_01149	1.33e-236	-	-	-	C	-	-	-	RnfC Barrel sandwich hybrid domain
NLADLHMP_01150	1.02e-20	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NLADLHMP_01152	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NLADLHMP_01155	1.18e-08	-	-	-	S	-	-	-	peptidoglycan binding
NLADLHMP_01156	6.42e-68	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NLADLHMP_01157	2.72e-282	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NLADLHMP_01159	1.55e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NLADLHMP_01160	7.39e-295	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NLADLHMP_01161	2.92e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLADLHMP_01162	2.4e-146	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLADLHMP_01163	4.1e-39	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NLADLHMP_01164	2.39e-146	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NLADLHMP_01165	7.85e-30	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NLADLHMP_01167	6.75e-81	-	-	-	H	-	-	-	Methyltransferase domain
NLADLHMP_01168	2.96e-47	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NLADLHMP_01169	2.79e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLADLHMP_01170	3.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NLADLHMP_01172	6.29e-127	cadD	-	-	P	-	-	-	Cadmium resistance transporter
NLADLHMP_01173	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLADLHMP_01174	0.0	-	-	-	L	-	-	-	DNA helicase
NLADLHMP_01176	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NLADLHMP_01177	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NLADLHMP_01178	6.58e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLADLHMP_01179	8.27e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NLADLHMP_01180	1.41e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01181	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NLADLHMP_01182	2.26e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NLADLHMP_01183	1.38e-200	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NLADLHMP_01184	1.26e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NLADLHMP_01185	3.16e-152	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NLADLHMP_01186	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLADLHMP_01188	1.68e-22	-	-	-	-	-	-	-	-
NLADLHMP_01189	1.68e-253	oatA	-	-	I	-	-	-	Acyltransferase
NLADLHMP_01190	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLADLHMP_01191	6.53e-221	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLADLHMP_01192	1.92e-240	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NLADLHMP_01194	1.31e-140	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
NLADLHMP_01195	4.54e-75	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
NLADLHMP_01196	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NLADLHMP_01198	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
NLADLHMP_01200	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
NLADLHMP_01201	4.75e-153	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NLADLHMP_01202	2.36e-252	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLADLHMP_01203	1.98e-22	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NLADLHMP_01205	7.65e-47	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NLADLHMP_01206	3.64e-153	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NLADLHMP_01207	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NLADLHMP_01208	4.54e-263	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NLADLHMP_01209	2.61e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NLADLHMP_01210	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
NLADLHMP_01211	1.97e-64	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NLADLHMP_01212	1.22e-222	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NLADLHMP_01213	4.53e-112	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NLADLHMP_01214	1.72e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLADLHMP_01215	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NLADLHMP_01216	1.17e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NLADLHMP_01217	3.38e-110	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
NLADLHMP_01218	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NLADLHMP_01220	4.53e-62	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NLADLHMP_01221	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NLADLHMP_01222	4.94e-21	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NLADLHMP_01223	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NLADLHMP_01224	1.66e-29	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLADLHMP_01225	2.34e-299	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLADLHMP_01226	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NLADLHMP_01227	2.75e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NLADLHMP_01228	4.85e-128	-	-	-	EG	-	-	-	EamA-like transporter family
NLADLHMP_01229	5.76e-219	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NLADLHMP_01230	1.1e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NLADLHMP_01231	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NLADLHMP_01232	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NLADLHMP_01233	3.93e-87	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NLADLHMP_01234	7.23e-52	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
NLADLHMP_01235	1.47e-223	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NLADLHMP_01236	3.38e-139	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLADLHMP_01237	2.07e-196	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NLADLHMP_01238	2.11e-111	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NLADLHMP_01239	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NLADLHMP_01240	2.24e-23	-	-	-	L	-	-	-	nuclease
NLADLHMP_01241	7.41e-17	-	-	-	-	-	-	-	-
NLADLHMP_01243	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLADLHMP_01244	6.85e-39	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NLADLHMP_01245	1.33e-198	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLADLHMP_01246	3.54e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NLADLHMP_01247	2.78e-08	-	-	-	-	-	-	-	-
NLADLHMP_01248	1.97e-84	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLADLHMP_01249	4.82e-68	repB	-	-	L	-	-	-	Initiator Replication protein
NLADLHMP_01250	3.82e-21	XK26_06135	-	-	D	-	-	-	Plasmid recombination enzyme
NLADLHMP_01251	4.87e-92	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	This enzyme is an effector of chloramphenicol resistance in bacteria
NLADLHMP_01252	2e-51	-	-	-	L	-	-	-	Replication initiation factor
NLADLHMP_01253	3.15e-311	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NLADLHMP_01254	0.0	XK27_03330	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NLADLHMP_01255	4.31e-83	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NLADLHMP_01256	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NLADLHMP_01257	1.97e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NLADLHMP_01258	2.71e-107	-	-	-	S	-	-	-	membrane
NLADLHMP_01259	1.39e-100	-	-	-	S	-	-	-	VIT family
NLADLHMP_01260	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NLADLHMP_01262	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLADLHMP_01263	4.39e-81	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NLADLHMP_01264	6.33e-133	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NLADLHMP_01265	1.52e-12	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NLADLHMP_01266	2.13e-100	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NLADLHMP_01267	1.85e-89	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NLADLHMP_01268	1.39e-128	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NLADLHMP_01269	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NLADLHMP_01270	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLADLHMP_01271	1.13e-277	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NLADLHMP_01272	5.52e-293	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NLADLHMP_01273	4.68e-131	-	-	-	G	-	-	-	MucBP domain
NLADLHMP_01274	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NLADLHMP_01275	9.7e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
NLADLHMP_01277	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NLADLHMP_01278	1.44e-142	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLADLHMP_01280	7.2e-142	ydhF	-	-	S	-	-	-	Aldo keto reductase
NLADLHMP_01281	6.42e-32	-	-	-	K	-	-	-	regulatory protein
NLADLHMP_01282	1.83e-172	-	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_01283	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NLADLHMP_01284	2.94e-157	yvgN	-	-	C	-	-	-	Aldo keto reductase
NLADLHMP_01285	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NLADLHMP_01286	1.64e-13	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NLADLHMP_01287	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NLADLHMP_01288	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLADLHMP_01290	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NLADLHMP_01291	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NLADLHMP_01292	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLADLHMP_01293	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLADLHMP_01294	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NLADLHMP_01295	1.65e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NLADLHMP_01296	2.65e-112	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLADLHMP_01298	1.21e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NLADLHMP_01299	4.78e-124	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLADLHMP_01300	3.82e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NLADLHMP_01301	1.74e-180	-	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_01304	2.39e-26	-	-	-	-	-	-	-	-
NLADLHMP_01305	3.98e-41	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NLADLHMP_01306	3.36e-193	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLADLHMP_01307	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NLADLHMP_01308	2.34e-210	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NLADLHMP_01310	1.88e-62	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NLADLHMP_01311	9.49e-122	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NLADLHMP_01312	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLADLHMP_01313	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLADLHMP_01314	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NLADLHMP_01315	2.68e-45	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NLADLHMP_01316	1.51e-81	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NLADLHMP_01317	4.89e-38	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NLADLHMP_01318	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NLADLHMP_01319	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLADLHMP_01320	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLADLHMP_01321	1.84e-186	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLADLHMP_01322	6.92e-105	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NLADLHMP_01323	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLADLHMP_01324	1.46e-91	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
NLADLHMP_01325	9.29e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NLADLHMP_01326	4.22e-13	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NLADLHMP_01327	2.48e-123	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NLADLHMP_01328	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLADLHMP_01329	9.53e-94	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NLADLHMP_01331	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLADLHMP_01332	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NLADLHMP_01333	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLADLHMP_01334	3.3e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NLADLHMP_01335	9.86e-105	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NLADLHMP_01336	2.74e-39	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLADLHMP_01337	1.07e-60	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NLADLHMP_01338	6.1e-48	-	-	-	K	-	-	-	Peptidase S24-like
NLADLHMP_01341	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLADLHMP_01342	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLADLHMP_01343	7.4e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NLADLHMP_01344	1.35e-150	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLADLHMP_01345	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLADLHMP_01346	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLADLHMP_01347	2.85e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
NLADLHMP_01348	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NLADLHMP_01349	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NLADLHMP_01350	1.85e-84	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NLADLHMP_01353	5.91e-61	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLADLHMP_01354	9.68e-126	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NLADLHMP_01355	5.17e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NLADLHMP_01356	4.97e-33	-	-	-	-	-	-	-	-
NLADLHMP_01357	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLADLHMP_01358	3.71e-108	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NLADLHMP_01360	1.19e-63	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
NLADLHMP_01361	4.76e-132	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
NLADLHMP_01362	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NLADLHMP_01363	2.2e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01365	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NLADLHMP_01366	2e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NLADLHMP_01367	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLADLHMP_01368	2.46e-198	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLADLHMP_01369	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLADLHMP_01370	5e-45	-	-	-	-	-	-	-	-
NLADLHMP_01371	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NLADLHMP_01372	1.47e-45	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NLADLHMP_01373	3.7e-67	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NLADLHMP_01374	1.83e-151	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NLADLHMP_01375	9.7e-40	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLADLHMP_01376	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
NLADLHMP_01377	2.08e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NLADLHMP_01378	2.47e-114	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NLADLHMP_01380	1.37e-65	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
NLADLHMP_01384	3.19e-59	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
NLADLHMP_01385	7.02e-66	-	-	-	S	-	-	-	Filamentation induced by cAMP protein fic
NLADLHMP_01386	3.42e-135	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
NLADLHMP_01387	2.02e-216	-	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NLADLHMP_01388	1.16e-162	-	-	-	S	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NLADLHMP_01389	2.21e-09	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NLADLHMP_01390	2.26e-06	-	-	CBM50	MNU	ko:K02395,ko:K19220,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLADLHMP_01391	5.61e-108	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
NLADLHMP_01392	9.69e-38	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NLADLHMP_01393	4.49e-69	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NLADLHMP_01394	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NLADLHMP_01395	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLADLHMP_01396	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLADLHMP_01397	2.82e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLADLHMP_01398	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLADLHMP_01399	5.17e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NLADLHMP_01401	1.96e-54	-	-	-	-	-	-	-	-
NLADLHMP_01402	1.32e-41	-	-	-	K	-	-	-	GNAT family
NLADLHMP_01403	5.6e-263	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NLADLHMP_01404	5.08e-278	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NLADLHMP_01412	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NLADLHMP_01413	5.35e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLADLHMP_01414	1.12e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NLADLHMP_01415	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NLADLHMP_01416	7.05e-151	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLADLHMP_01418	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NLADLHMP_01419	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLADLHMP_01420	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLADLHMP_01421	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLADLHMP_01423	4.53e-10	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NLADLHMP_01427	1.03e-249	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NLADLHMP_01428	7e-94	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NLADLHMP_01429	6.41e-167	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
NLADLHMP_01430	1.97e-126	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NLADLHMP_01431	3.14e-104	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NLADLHMP_01433	2.83e-196	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NLADLHMP_01434	2.46e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NLADLHMP_01435	2.48e-215	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLADLHMP_01436	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLADLHMP_01437	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLADLHMP_01439	8.67e-105	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NLADLHMP_01440	6.27e-41	-	-	-	S	-	-	-	CHY zinc finger
NLADLHMP_01441	2.23e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_01442	1.39e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NLADLHMP_01443	1.17e-06	-	-	-	-	-	-	-	-
NLADLHMP_01444	2.02e-35	-	-	-	M	-	-	-	Glycosyl transferases group 1
NLADLHMP_01445	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLADLHMP_01446	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLADLHMP_01447	1.52e-68	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLADLHMP_01448	1.85e-29	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NLADLHMP_01450	1.1e-72	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NLADLHMP_01451	2.37e-145	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
NLADLHMP_01452	1.06e-28	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NLADLHMP_01459	3.41e-05	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
NLADLHMP_01460	9.84e-30	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NLADLHMP_01462	5.89e-122	-	-	-	M	-	-	-	Prophage endopeptidase tail
NLADLHMP_01463	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
NLADLHMP_01464	2.97e-184	-	-	-	S	-	-	-	Phage tail protein
NLADLHMP_01465	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NLADLHMP_01466	8.1e-122	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLADLHMP_01467	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NLADLHMP_01468	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NLADLHMP_01469	3.97e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NLADLHMP_01470	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NLADLHMP_01471	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NLADLHMP_01472	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NLADLHMP_01473	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
NLADLHMP_01474	1.77e-253	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NLADLHMP_01475	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLADLHMP_01476	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLADLHMP_01477	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NLADLHMP_01478	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLADLHMP_01479	3.12e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLADLHMP_01480	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLADLHMP_01481	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NLADLHMP_01482	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NLADLHMP_01483	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLADLHMP_01484	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLADLHMP_01485	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLADLHMP_01486	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLADLHMP_01487	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLADLHMP_01488	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLADLHMP_01489	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLADLHMP_01490	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLADLHMP_01491	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLADLHMP_01492	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NLADLHMP_01493	5.18e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLADLHMP_01494	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLADLHMP_01495	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLADLHMP_01496	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLADLHMP_01497	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLADLHMP_01498	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NLADLHMP_01499	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLADLHMP_01500	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLADLHMP_01501	2.53e-53	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLADLHMP_01502	3.31e-60	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
NLADLHMP_01503	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLADLHMP_01504	8.29e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLADLHMP_01505	4.5e-23	-	-	-	V	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NLADLHMP_01507	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NLADLHMP_01508	4.1e-128	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01509	6.78e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NLADLHMP_01510	3.75e-49	-	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_01511	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
NLADLHMP_01512	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NLADLHMP_01513	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLADLHMP_01514	6.98e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
NLADLHMP_01515	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NLADLHMP_01516	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NLADLHMP_01517	7.37e-174	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
NLADLHMP_01518	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NLADLHMP_01519	1.54e-80	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
NLADLHMP_01520	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLADLHMP_01521	1.03e-88	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NLADLHMP_01522	0.0	-	-	-	L	-	-	-	helicase activity
NLADLHMP_01523	3.05e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
NLADLHMP_01524	1.05e-74	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
NLADLHMP_01525	3.12e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
NLADLHMP_01526	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NLADLHMP_01527	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NLADLHMP_01528	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NLADLHMP_01529	4.05e-180	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NLADLHMP_01530	2.16e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLADLHMP_01531	2.87e-152	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
NLADLHMP_01533	6.05e-45	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NLADLHMP_01534	6.64e-267	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLADLHMP_01535	5.09e-183	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NLADLHMP_01536	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLADLHMP_01537	6.22e-296	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLADLHMP_01538	5.47e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLADLHMP_01539	9.79e-205	camS	-	-	S	-	-	-	sex pheromone
NLADLHMP_01540	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLADLHMP_01541	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NLADLHMP_01542	2.7e-181	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLADLHMP_01543	1.05e-312	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLADLHMP_01544	8.65e-43	yacL	-	-	S	-	-	-	domain protein
NLADLHMP_01545	3.88e-245	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
NLADLHMP_01546	2.16e-120	baeS	-	-	T	-	-	-	Histidine kinase
NLADLHMP_01547	3.08e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
NLADLHMP_01548	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NLADLHMP_01549	1.01e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NLADLHMP_01550	1.4e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NLADLHMP_01551	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NLADLHMP_01552	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLADLHMP_01553	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLADLHMP_01554	1.23e-139	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NLADLHMP_01555	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
NLADLHMP_01556	9.12e-81	-	-	-	D	-	-	-	peptidase
NLADLHMP_01557	1.13e-59	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLADLHMP_01558	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NLADLHMP_01559	1.41e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NLADLHMP_01560	3.61e-268	potE	-	-	E	-	-	-	Amino Acid
NLADLHMP_01561	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NLADLHMP_01562	5.65e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLADLHMP_01563	2.78e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NLADLHMP_01564	3.94e-163	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NLADLHMP_01565	2.4e-94	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NLADLHMP_01566	2.76e-33	-	-	-	-	-	-	-	-
NLADLHMP_01567	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
NLADLHMP_01568	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NLADLHMP_01569	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NLADLHMP_01570	1.3e-142	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NLADLHMP_01571	1.05e-291	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
NLADLHMP_01572	1.28e-180	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NLADLHMP_01573	2.44e-110	-	-	-	-	-	-	-	-
NLADLHMP_01574	3.09e-149	-	-	-	L	-	-	-	AAA domain
NLADLHMP_01575	7.97e-308	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NLADLHMP_01576	2.78e-67	-	-	-	S	-	-	-	Siphovirus Gp157
NLADLHMP_01577	1.09e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NLADLHMP_01578	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NLADLHMP_01580	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NLADLHMP_01581	8.36e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NLADLHMP_01582	6.39e-69	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
NLADLHMP_01583	5.48e-188	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NLADLHMP_01587	3.89e-197	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLADLHMP_01588	1.36e-96	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NLADLHMP_01593	5.1e-273	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NLADLHMP_01597	9.7e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NLADLHMP_01599	2.8e-59	-	-	-	M	-	-	-	Prophage endopeptidase tail
NLADLHMP_01600	1.47e-19	-	-	-	S	-	-	-	phage tail
NLADLHMP_01601	1.07e-186	-	-	-	S	-	-	-	peptidoglycan catabolic process
NLADLHMP_01603	3.47e-69	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
NLADLHMP_01604	4.01e-101	-	-	-	S	-	-	-	Phage portal protein
NLADLHMP_01605	6.69e-226	-	-	-	S	-	-	-	Terminase
NLADLHMP_01606	1.16e-14	-	-	-	S	-	-	-	Phage terminase, small subunit
NLADLHMP_01607	1.04e-34	-	-	-	V	-	-	-	HNH nucleases
NLADLHMP_01608	4.65e-30	-	-	-	-	-	-	-	-
NLADLHMP_01609	2.4e-19	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
NLADLHMP_01610	6e-08	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
NLADLHMP_01611	2.15e-36	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
NLADLHMP_01613	1.51e-126	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLADLHMP_01614	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
NLADLHMP_01615	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NLADLHMP_01616	2.1e-171	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLADLHMP_01617	1.27e-234	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLADLHMP_01618	7.42e-196	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLADLHMP_01619	1.83e-75	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLADLHMP_01620	2.32e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NLADLHMP_01621	1.5e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NLADLHMP_01622	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NLADLHMP_01623	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NLADLHMP_01627	4.78e-94	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
NLADLHMP_01628	5.33e-215	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NLADLHMP_01629	3.21e-243	-	-	-	M	-	-	-	NlpC p60 family protein
NLADLHMP_01630	3.88e-76	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
NLADLHMP_01631	1.03e-49	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
NLADLHMP_01632	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NLADLHMP_01633	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NLADLHMP_01634	8.93e-16	-	-	-	K	-	-	-	Transcriptional regulator
NLADLHMP_01635	1.31e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NLADLHMP_01637	7.07e-53	-	-	-	K	-	-	-	LytTr DNA-binding domain
NLADLHMP_01638	1.32e-144	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NLADLHMP_01639	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLADLHMP_01640	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLADLHMP_01641	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NLADLHMP_01642	4.1e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NLADLHMP_01643	6.01e-60	-	-	-	C	-	-	-	Flavodoxin
NLADLHMP_01644	6.56e-73	yphH	-	-	S	-	-	-	Cupin domain
NLADLHMP_01645	5.1e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NLADLHMP_01646	1.03e-176	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NLADLHMP_01647	4.23e-135	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NLADLHMP_01648	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLADLHMP_01649	3.15e-56	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLADLHMP_01650	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NLADLHMP_01651	1.06e-153	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NLADLHMP_01652	0.000105	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NLADLHMP_01653	2.56e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NLADLHMP_01654	2.64e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
NLADLHMP_01655	3.74e-88	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain