ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NNFDHMCK_00004 1.4e-95 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNFDHMCK_00005 6.96e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NNFDHMCK_00006 5.27e-284 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNFDHMCK_00007 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNFDHMCK_00008 9.96e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNFDHMCK_00009 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNFDHMCK_00010 8.62e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NNFDHMCK_00011 8.72e-269 yhdG - - E ko:K03294 - ko00000 Amino Acid
NNFDHMCK_00012 4.97e-69 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NNFDHMCK_00013 5.33e-17 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NNFDHMCK_00014 9.05e-123 - - - - - - - -
NNFDHMCK_00015 1.32e-17 - - - - - - - -
NNFDHMCK_00016 6.02e-133 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_00017 6.87e-126 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNFDHMCK_00018 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00019 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00020 5.29e-212 steT - - E ko:K03294 - ko00000 amino acid
NNFDHMCK_00021 3.09e-160 mocA - - S - - - Oxidoreductase
NNFDHMCK_00022 9.82e-202 yfmL - - L - - - DEAD DEAH box helicase
NNFDHMCK_00025 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NNFDHMCK_00026 1.64e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NNFDHMCK_00027 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
NNFDHMCK_00028 9.55e-96 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNFDHMCK_00029 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NNFDHMCK_00030 1.29e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NNFDHMCK_00033 4.18e-28 - - - - - - - -
NNFDHMCK_00034 7.02e-90 - - - - - - - -
NNFDHMCK_00049 4.65e-30 - - - - - - - -
NNFDHMCK_00050 1.04e-34 - - - V - - - HNH nucleases
NNFDHMCK_00051 1.16e-14 - - - S - - - Phage terminase, small subunit
NNFDHMCK_00052 6.69e-226 - - - S - - - Terminase
NNFDHMCK_00053 4.01e-101 - - - S - - - Phage portal protein
NNFDHMCK_00054 3.47e-69 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
NNFDHMCK_00056 1.07e-186 - - - S - - - peptidoglycan catabolic process
NNFDHMCK_00057 1.47e-19 - - - S - - - phage tail
NNFDHMCK_00058 2.8e-59 - - - M - - - Prophage endopeptidase tail
NNFDHMCK_00060 9.7e-82 - - - S - - - Domain of unknown function (DUF2479)
NNFDHMCK_00066 1.85e-29 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NNFDHMCK_00067 6.4e-148 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NNFDHMCK_00068 6.11e-79 - - - S - - - Protein of unknown function (DUF1211)
NNFDHMCK_00069 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNFDHMCK_00070 2.65e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNFDHMCK_00071 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NNFDHMCK_00072 6.88e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NNFDHMCK_00074 2.66e-148 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNFDHMCK_00075 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNFDHMCK_00076 3.98e-148 - - - - - - - -
NNFDHMCK_00077 4.27e-143 - - - - - - - -
NNFDHMCK_00078 2.61e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NNFDHMCK_00079 4.54e-263 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNFDHMCK_00080 1.32e-144 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NNFDHMCK_00081 3.24e-42 FbpA - - K - - - Fibronectin-binding protein
NNFDHMCK_00082 2.25e-65 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNFDHMCK_00083 1.72e-105 ylmH - - S - - - S4 domain protein
NNFDHMCK_00084 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NNFDHMCK_00085 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNFDHMCK_00086 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNFDHMCK_00087 1.1e-241 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNFDHMCK_00088 2.35e-46 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNFDHMCK_00089 2.92e-164 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNFDHMCK_00090 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
NNFDHMCK_00091 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNFDHMCK_00092 0.0 ydaO - - E - - - amino acid
NNFDHMCK_00093 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NNFDHMCK_00094 1.53e-67 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNFDHMCK_00095 4.32e-113 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNFDHMCK_00096 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNFDHMCK_00097 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNFDHMCK_00098 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NNFDHMCK_00099 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNFDHMCK_00100 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNFDHMCK_00101 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNFDHMCK_00102 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNFDHMCK_00103 9.43e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNFDHMCK_00104 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNFDHMCK_00105 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NNFDHMCK_00106 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNFDHMCK_00107 2.29e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNFDHMCK_00108 5.01e-22 yneR - - - - - - -
NNFDHMCK_00109 5.06e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNFDHMCK_00110 7.22e-282 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NNFDHMCK_00111 9.5e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNFDHMCK_00112 3.68e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNFDHMCK_00113 2.97e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_00114 2.56e-140 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NNFDHMCK_00115 2.64e-212 - - - S - - - Putative threonine/serine exporter
NNFDHMCK_00116 3.74e-88 - - - J - - - Acetyltransferase (GNAT) domain
NNFDHMCK_00117 3.71e-09 - - - S - - - Putative adhesin
NNFDHMCK_00118 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
NNFDHMCK_00119 1.03e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
NNFDHMCK_00122 7.51e-26 - - - S - - - Plasmid replication protein
NNFDHMCK_00123 1.68e-305 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NNFDHMCK_00124 4.24e-314 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG3505 Type IV secretory pathway, VirD4 components
NNFDHMCK_00125 7.93e-95 - - - S - - - EDD domain protein, DegV family
NNFDHMCK_00126 3.9e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
NNFDHMCK_00127 7.78e-53 - - - S - - - ASCH
NNFDHMCK_00128 2.15e-235 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNFDHMCK_00129 1.25e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NNFDHMCK_00130 2.13e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNFDHMCK_00131 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNFDHMCK_00132 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
NNFDHMCK_00133 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNFDHMCK_00134 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
NNFDHMCK_00135 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNFDHMCK_00136 4.19e-18 cvpA - - S - - - Colicin V production protein
NNFDHMCK_00137 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNFDHMCK_00138 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNFDHMCK_00139 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
NNFDHMCK_00140 7.28e-93 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNFDHMCK_00141 1.47e-52 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NNFDHMCK_00143 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
NNFDHMCK_00144 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NNFDHMCK_00145 7.92e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNFDHMCK_00146 3.59e-60 - - - S - - - Short repeat of unknown function (DUF308)
NNFDHMCK_00148 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNFDHMCK_00149 4.68e-131 - - - G - - - MucBP domain
NNFDHMCK_00150 1.18e-29 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NNFDHMCK_00153 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNFDHMCK_00154 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNFDHMCK_00155 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NNFDHMCK_00156 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNFDHMCK_00157 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNFDHMCK_00158 3.07e-87 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NNFDHMCK_00159 3.7e-67 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NNFDHMCK_00161 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNFDHMCK_00162 8.17e-96 - - - K - - - Helix-turn-helix domain, rpiR family
NNFDHMCK_00163 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NNFDHMCK_00164 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NNFDHMCK_00165 5.76e-219 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NNFDHMCK_00167 9.48e-97 uspA - - T - - - universal stress protein
NNFDHMCK_00168 1.31e-70 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NNFDHMCK_00169 2.99e-252 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NNFDHMCK_00170 2.95e-158 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNFDHMCK_00172 1.03e-145 - - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_00173 3.32e-133 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNFDHMCK_00174 8.24e-53 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNFDHMCK_00175 4.16e-226 rsmF - - J - - - NOL1 NOP2 sun family protein
NNFDHMCK_00176 9.38e-81 - - - - - - - -
NNFDHMCK_00177 3.03e-103 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNFDHMCK_00178 2.04e-143 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NNFDHMCK_00179 1.36e-78 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NNFDHMCK_00180 1.09e-237 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNFDHMCK_00181 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NNFDHMCK_00182 1.52e-264 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNFDHMCK_00184 8.38e-80 - - - K - - - helix_turn_helix, arabinose operon control protein
NNFDHMCK_00185 4.77e-70 - - - S - - - Membrane
NNFDHMCK_00186 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNFDHMCK_00187 1.99e-107 - - - L - - - Helicase C-terminal domain protein
NNFDHMCK_00188 6.53e-49 - - - L - - - Helicase C-terminal domain protein
NNFDHMCK_00190 2.74e-180 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
NNFDHMCK_00191 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNFDHMCK_00192 7e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NNFDHMCK_00193 1.13e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNFDHMCK_00194 1.22e-276 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
NNFDHMCK_00195 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NNFDHMCK_00196 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NNFDHMCK_00197 1.5e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NNFDHMCK_00198 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NNFDHMCK_00199 6.43e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NNFDHMCK_00200 3.91e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NNFDHMCK_00201 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NNFDHMCK_00202 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNFDHMCK_00203 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNFDHMCK_00204 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNFDHMCK_00205 7.33e-71 - - - - - - - -
NNFDHMCK_00206 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNFDHMCK_00207 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NNFDHMCK_00208 0.0 - - - L - - - Transposase DDE domain group 1
NNFDHMCK_00209 9.45e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 purine ribonucleoside salvage
NNFDHMCK_00210 6.77e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 adenylyltransferase
NNFDHMCK_00211 1.99e-181 - - - Q - - - Protein of unknown function (DUF1698)
NNFDHMCK_00212 1.26e-211 - - - L - - - Nucleotidyltransferase domain
NNFDHMCK_00213 2.77e-45 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNFDHMCK_00214 0.0 - - - L - - - Recombinase
NNFDHMCK_00215 1.91e-93 - - - S - - - Recombinase
NNFDHMCK_00216 7.01e-109 - - - L - - - COG1961 Site-specific recombinases, DNA invertase Pin homologs
NNFDHMCK_00217 3.98e-116 yeeC - - P - - - T5orf172
NNFDHMCK_00218 0.0 - - - L - - - DEAD-like helicases superfamily
NNFDHMCK_00219 2.31e-93 yeeA - - V - - - Type II restriction enzyme, methylase subunits
NNFDHMCK_00220 4.14e-292 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
NNFDHMCK_00222 2.38e-148 - - - P - - - Rhodanese Homology Domain
NNFDHMCK_00223 9.43e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
NNFDHMCK_00224 4.85e-80 - - - S - - - Sulphur transport
NNFDHMCK_00226 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNFDHMCK_00227 8.08e-58 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNFDHMCK_00228 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
NNFDHMCK_00229 7.05e-110 - - - F - - - glutamine amidotransferase
NNFDHMCK_00230 2.43e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
NNFDHMCK_00231 1.01e-110 - - - S - - - hydrolase
NNFDHMCK_00232 1.28e-88 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NNFDHMCK_00233 2.83e-196 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNFDHMCK_00234 2.46e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNFDHMCK_00235 2.48e-215 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNFDHMCK_00236 3.98e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNFDHMCK_00237 1.77e-253 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNFDHMCK_00238 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNFDHMCK_00239 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNFDHMCK_00240 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNFDHMCK_00241 4.06e-30 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NNFDHMCK_00242 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNFDHMCK_00243 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNFDHMCK_00244 5.14e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NNFDHMCK_00245 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NNFDHMCK_00246 1.91e-187 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNFDHMCK_00247 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNFDHMCK_00248 3.53e-230 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NNFDHMCK_00250 4.97e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNFDHMCK_00252 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNFDHMCK_00253 3.66e-216 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNFDHMCK_00254 1.48e-148 ydbI - - K - - - AI-2E family transporter
NNFDHMCK_00255 2.09e-76 - - - EG - - - EamA-like transporter family
NNFDHMCK_00256 1.3e-97 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NNFDHMCK_00257 4.86e-148 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NNFDHMCK_00258 6.44e-34 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNFDHMCK_00259 5.56e-32 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
NNFDHMCK_00260 4.16e-118 - - - C - - - Luciferase-like monooxygenase
NNFDHMCK_00261 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NNFDHMCK_00262 3.65e-255 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NNFDHMCK_00263 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NNFDHMCK_00264 1.72e-174 - - - EG - - - EamA-like transporter family
NNFDHMCK_00265 1.27e-92 - - - L - - - DNA alkylation repair enzyme
NNFDHMCK_00266 1.28e-228 - - - L - - - Transposase DDE domain group 1
NNFDHMCK_00267 1.51e-75 ypuA - - S - - - Protein of unknown function (DUF1002)
NNFDHMCK_00268 2.57e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NNFDHMCK_00269 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNFDHMCK_00270 2.88e-53 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNFDHMCK_00271 2.97e-266 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NNFDHMCK_00272 1.13e-248 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNFDHMCK_00273 4.35e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNFDHMCK_00274 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
NNFDHMCK_00275 2.4e-146 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNFDHMCK_00276 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNFDHMCK_00277 1.92e-176 - - - E - - - Beta-eliminating lyase
NNFDHMCK_00278 3.15e-114 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NNFDHMCK_00279 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
NNFDHMCK_00280 8.87e-168 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNFDHMCK_00281 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNFDHMCK_00282 2.97e-132 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NNFDHMCK_00283 2.52e-51 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNFDHMCK_00284 3.44e-38 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNFDHMCK_00285 6.82e-30 - - - S - - - Protein conserved in bacteria
NNFDHMCK_00286 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNFDHMCK_00287 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NNFDHMCK_00288 4.44e-41 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NNFDHMCK_00289 1.13e-103 - - - L - - - Transposase, IS116 IS110 IS902 family
NNFDHMCK_00290 3.28e-67 - - - - - - - -
NNFDHMCK_00292 3.58e-23 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NNFDHMCK_00293 1.69e-59 yqhL - - P - - - Rhodanese-like protein
NNFDHMCK_00294 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NNFDHMCK_00295 1.22e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NNFDHMCK_00296 1.05e-41 - - - L - - - Helix-turn-helix domain
NNFDHMCK_00297 4.26e-89 - - - P - - - ArsC family
NNFDHMCK_00298 2.3e-187 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNFDHMCK_00299 2.26e-58 hpk7 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNFDHMCK_00300 1.99e-209 hpk7 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNFDHMCK_00301 4.81e-151 - - - K - - - response regulator
NNFDHMCK_00302 1.61e-44 - - - S - - - Domain of unknown function DUF302
NNFDHMCK_00303 5.25e-22 - - - S - - - Domain of unknown function DUF302
NNFDHMCK_00304 1.4e-53 - - - S ko:K08982 - ko00000 membrane protein (DUF2078)
NNFDHMCK_00305 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 haloacid dehalogenase-like hydrolase
NNFDHMCK_00306 1.74e-103 - - - K - - - Penicillinase repressor
NNFDHMCK_00313 3.54e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NNFDHMCK_00314 5.6e-17 - - - - - - - -
NNFDHMCK_00315 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNFDHMCK_00316 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NNFDHMCK_00317 1.63e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNFDHMCK_00318 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNFDHMCK_00319 8.74e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNFDHMCK_00320 2.26e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NNFDHMCK_00321 2.13e-103 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
NNFDHMCK_00322 7.47e-152 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NNFDHMCK_00323 5.19e-75 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
NNFDHMCK_00324 4.54e-75 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
NNFDHMCK_00325 1.31e-140 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
NNFDHMCK_00327 1.37e-184 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
NNFDHMCK_00328 5.12e-312 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
NNFDHMCK_00329 5.08e-241 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NNFDHMCK_00330 4.45e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNFDHMCK_00331 9.74e-78 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNFDHMCK_00332 1.82e-246 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNFDHMCK_00333 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNFDHMCK_00334 7.63e-222 fusA1 - - J - - - elongation factor G
NNFDHMCK_00335 9.87e-35 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNFDHMCK_00336 3.54e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NNFDHMCK_00337 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNFDHMCK_00338 1.43e-266 fucI 5.3.1.25, 5.3.1.3 - G ko:K01818 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Converts the aldose L-fucose into the corresponding ketose L-fuculose
NNFDHMCK_00339 2.05e-159 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, N-terminal domain
NNFDHMCK_00340 5.49e-230 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNFDHMCK_00341 4.62e-62 fucU 5.1.3.29 - G ko:K02431 - ko00000,ko01000 RbsD / FucU transport protein family
NNFDHMCK_00342 2.13e-227 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NNFDHMCK_00343 1.27e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NNFDHMCK_00344 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNFDHMCK_00345 2.1e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NNFDHMCK_00346 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
NNFDHMCK_00347 2.11e-131 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNFDHMCK_00348 5.11e-112 - - - S - - - NADPH-dependent FMN reductase
NNFDHMCK_00349 9.23e-36 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNFDHMCK_00350 1.09e-87 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNFDHMCK_00352 7.52e-193 - - - EGP - - - Major Facilitator
NNFDHMCK_00353 2.95e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
NNFDHMCK_00354 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NNFDHMCK_00355 4.74e-45 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNFDHMCK_00356 1.41e-148 cps3J - - M - - - Domain of unknown function (DUF4422)
NNFDHMCK_00357 1.03e-75 - - - S - - - Glycosyltransferase like family 2
NNFDHMCK_00358 2.69e-179 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNFDHMCK_00359 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NNFDHMCK_00360 6.16e-237 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNFDHMCK_00361 5.97e-166 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNFDHMCK_00362 2.88e-146 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
NNFDHMCK_00364 3.67e-110 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NNFDHMCK_00366 1.88e-62 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NNFDHMCK_00367 2.42e-33 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NNFDHMCK_00368 1.19e-12 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNFDHMCK_00369 3.15e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NNFDHMCK_00370 1.37e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNFDHMCK_00371 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NNFDHMCK_00372 5.7e-82 - - - S - - - ECF transporter, substrate-specific component
NNFDHMCK_00373 6.23e-164 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNFDHMCK_00374 2.28e-311 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NNFDHMCK_00375 1.6e-89 mleR - - K - - - LysR family
NNFDHMCK_00376 2.32e-21 napB - - K - - - transcriptional
NNFDHMCK_00377 7.25e-36 - - - S - - - Protein of unknown function (DUF421)
NNFDHMCK_00378 4.36e-38 yviA - - S - - - Protein of unknown function (DUF421)
NNFDHMCK_00379 3e-36 - - - S - - - Protein of unknown function (DUF3290)
NNFDHMCK_00380 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNFDHMCK_00381 0.0 - - - S - - - membrane
NNFDHMCK_00382 4.3e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNFDHMCK_00383 7.63e-265 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NNFDHMCK_00384 1.68e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NNFDHMCK_00385 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNFDHMCK_00386 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NNFDHMCK_00387 7.88e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NNFDHMCK_00388 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NNFDHMCK_00389 2.76e-77 - - - L - - - Probable transposase
NNFDHMCK_00390 5.47e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNFDHMCK_00391 9.79e-205 camS - - S - - - sex pheromone
NNFDHMCK_00392 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNFDHMCK_00393 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NNFDHMCK_00394 2.7e-181 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNFDHMCK_00395 5.39e-43 hxlR - - K - - - Transcriptional regulator, HxlR family
NNFDHMCK_00396 5.49e-218 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNFDHMCK_00397 1.71e-131 gntR - - K - - - UbiC transcription regulator-associated domain protein
NNFDHMCK_00398 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NNFDHMCK_00399 5.94e-107 pncA - - Q - - - isochorismatase
NNFDHMCK_00400 1.61e-81 pgm1 - - G - - - phosphoglycerate mutase
NNFDHMCK_00401 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNFDHMCK_00402 1.68e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NNFDHMCK_00403 1.5e-315 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NNFDHMCK_00404 1.55e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNFDHMCK_00407 3.52e-225 XK27_08315 - - M - - - Sulfatase
NNFDHMCK_00408 7.25e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NNFDHMCK_00409 1.81e-24 - - - - - - - -
NNFDHMCK_00410 3.58e-132 - - - E - - - AzlC protein
NNFDHMCK_00411 2.61e-52 - - - S - - - branched-chain amino acid
NNFDHMCK_00412 3.45e-81 - - - I - - - alpha/beta hydrolase fold
NNFDHMCK_00413 1.65e-24 - - - - - - - -
NNFDHMCK_00414 6.46e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
NNFDHMCK_00415 1.23e-27 - - - - - - - -
NNFDHMCK_00416 1.01e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNFDHMCK_00417 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
NNFDHMCK_00418 1.18e-129 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
NNFDHMCK_00419 1.3e-53 yjbH - - Q - - - Thioredoxin
NNFDHMCK_00420 8.74e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NNFDHMCK_00421 5.19e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NNFDHMCK_00422 2.51e-139 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNFDHMCK_00423 2.78e-128 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNFDHMCK_00424 6.9e-44 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NNFDHMCK_00425 7.25e-234 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NNFDHMCK_00426 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNFDHMCK_00427 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NNFDHMCK_00428 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NNFDHMCK_00429 3.07e-68 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNFDHMCK_00430 1.63e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNFDHMCK_00431 7.25e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NNFDHMCK_00432 2.45e-143 - - - K - - - helix_turn _helix lactose operon repressor
NNFDHMCK_00433 6.29e-47 treC - - G - - - Psort location Cytoplasmic, score
NNFDHMCK_00434 2.08e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NNFDHMCK_00435 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
NNFDHMCK_00436 1.01e-281 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NNFDHMCK_00437 4.42e-186 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
NNFDHMCK_00438 5.55e-126 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NNFDHMCK_00439 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NNFDHMCK_00440 1.18e-295 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNFDHMCK_00441 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NNFDHMCK_00442 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNFDHMCK_00443 8.99e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNFDHMCK_00444 3.16e-152 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00445 1.26e-132 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNFDHMCK_00446 5.62e-200 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNFDHMCK_00447 2.26e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NNFDHMCK_00448 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNFDHMCK_00449 1.41e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_00450 8.27e-86 yciB - - M - - - ErfK YbiS YcfS YnhG
NNFDHMCK_00451 6.58e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNFDHMCK_00453 1.17e-239 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
NNFDHMCK_00455 1.5e-216 - - - S - - - Putative peptidoglycan binding domain
NNFDHMCK_00456 1.07e-32 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NNFDHMCK_00457 8.38e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NNFDHMCK_00458 1.44e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NNFDHMCK_00459 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNFDHMCK_00460 5.02e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNFDHMCK_00461 7.89e-279 pepF - - E - - - Oligopeptidase F
NNFDHMCK_00462 9.44e-121 yicL - - EG - - - EamA-like transporter family
NNFDHMCK_00463 3.61e-79 uspA3 - - T - - - universal stress protein
NNFDHMCK_00465 3.02e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
NNFDHMCK_00466 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNFDHMCK_00467 1.66e-230 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNFDHMCK_00468 4.14e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNFDHMCK_00469 1.54e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNFDHMCK_00470 9.92e-288 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNFDHMCK_00471 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNFDHMCK_00472 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NNFDHMCK_00473 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNFDHMCK_00474 4.09e-108 sip - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_00475 3.93e-89 - - - S - - - Calcineurin-like phosphoesterase
NNFDHMCK_00476 1.71e-31 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NNFDHMCK_00477 3.11e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNFDHMCK_00478 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNFDHMCK_00479 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNFDHMCK_00480 1.72e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNFDHMCK_00481 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNFDHMCK_00482 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNFDHMCK_00483 1.68e-253 oatA - - I - - - Acyltransferase
NNFDHMCK_00484 1.68e-22 - - - - - - - -
NNFDHMCK_00485 8.78e-18 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NNFDHMCK_00486 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
NNFDHMCK_00487 2.84e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
NNFDHMCK_00488 2.82e-42 - - - S - - - Domain of unknown function (DUF4811)
NNFDHMCK_00489 2.88e-50 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNFDHMCK_00490 4.71e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
NNFDHMCK_00491 5.62e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNFDHMCK_00492 2.69e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNFDHMCK_00493 2.6e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NNFDHMCK_00494 5.42e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NNFDHMCK_00495 4.53e-112 - - - S - - - Predicted membrane protein (DUF2207)
NNFDHMCK_00496 3.26e-11 - - - K ko:K03826 - ko00000,ko01000 Acetyltransferase, GNAT family
NNFDHMCK_00497 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
NNFDHMCK_00498 9.92e-121 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNFDHMCK_00499 6.03e-105 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NNFDHMCK_00500 2.69e-176 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NNFDHMCK_00501 8.6e-87 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NNFDHMCK_00502 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNFDHMCK_00503 2.92e-205 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNFDHMCK_00504 1.15e-251 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NNFDHMCK_00505 9.26e-134 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NNFDHMCK_00506 2.57e-77 nss - - M - - - transferase activity, transferring glycosyl groups
NNFDHMCK_00507 2.72e-08 - - - M - - - Psort location Cytoplasmic, score 8.87
NNFDHMCK_00508 1.49e-17 arbY - - M - - - family 8
NNFDHMCK_00510 6.08e-65 - - - M - - - transferase activity, transferring glycosyl groups
NNFDHMCK_00511 2.3e-43 - - - M - - - Glycosyl transferase, family 8
NNFDHMCK_00513 1.82e-70 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NNFDHMCK_00514 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNFDHMCK_00515 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNFDHMCK_00516 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNFDHMCK_00517 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NNFDHMCK_00518 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNFDHMCK_00519 3.12e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNFDHMCK_00520 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNFDHMCK_00521 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNFDHMCK_00522 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NNFDHMCK_00523 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNFDHMCK_00524 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNFDHMCK_00525 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNFDHMCK_00526 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNFDHMCK_00527 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNFDHMCK_00528 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNFDHMCK_00529 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNFDHMCK_00530 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNFDHMCK_00531 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNFDHMCK_00532 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NNFDHMCK_00533 5.18e-94 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNFDHMCK_00534 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNFDHMCK_00535 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNFDHMCK_00536 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNFDHMCK_00537 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNFDHMCK_00538 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNFDHMCK_00539 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NNFDHMCK_00540 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNFDHMCK_00541 7.65e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NNFDHMCK_00542 4.93e-217 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNFDHMCK_00543 1.09e-61 - - - K - - - SIS domain
NNFDHMCK_00544 1.37e-103 - - - L - - - Helicase C-terminal domain protein
NNFDHMCK_00545 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNFDHMCK_00546 4.31e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NNFDHMCK_00547 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NNFDHMCK_00548 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NNFDHMCK_00549 7.93e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNFDHMCK_00550 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NNFDHMCK_00551 7.08e-136 yueF - - S - - - AI-2E family transporter
NNFDHMCK_00552 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NNFDHMCK_00553 5.45e-243 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNFDHMCK_00554 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NNFDHMCK_00555 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NNFDHMCK_00556 1.19e-138 - - - E - - - Serine hydroxymethyltransferase
NNFDHMCK_00557 3.32e-13 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
NNFDHMCK_00558 5e-45 - - - - - - - -
NNFDHMCK_00559 3.22e-105 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNFDHMCK_00560 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNFDHMCK_00561 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNFDHMCK_00562 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NNFDHMCK_00563 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNFDHMCK_00564 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NNFDHMCK_00566 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNFDHMCK_00567 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NNFDHMCK_00568 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NNFDHMCK_00569 5.65e-160 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NNFDHMCK_00570 5.31e-278 yifK - - E ko:K03293 - ko00000 Amino acid permease
NNFDHMCK_00571 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNFDHMCK_00572 2.18e-72 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNFDHMCK_00573 6.38e-78 pgm3 - - G - - - phosphoglycerate mutase family
NNFDHMCK_00574 1.53e-181 - - - C - - - Aldo/keto reductase family
NNFDHMCK_00575 5.71e-315 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NNFDHMCK_00576 1.21e-25 - - - S - - - Cupredoxin-like domain
NNFDHMCK_00577 5.2e-57 - - - S - - - Cupredoxin-like domain
NNFDHMCK_00578 6.15e-191 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NNFDHMCK_00579 9.65e-230 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
NNFDHMCK_00580 2.85e-146 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
NNFDHMCK_00581 2.34e-77 - - - S - - - intracellular protease amidase
NNFDHMCK_00582 5.47e-167 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NNFDHMCK_00583 4.98e-88 - - - D - - - Peptidase family M23
NNFDHMCK_00585 4.91e-172 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
NNFDHMCK_00586 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
NNFDHMCK_00587 3.61e-268 potE - - E - - - Amino Acid
NNFDHMCK_00588 1.2e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NNFDHMCK_00589 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NNFDHMCK_00590 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NNFDHMCK_00591 6.42e-32 - - - K - - - regulatory protein
NNFDHMCK_00592 7.2e-142 ydhF - - S - - - Aldo keto reductase
NNFDHMCK_00594 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNFDHMCK_00595 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NNFDHMCK_00596 1.5e-22 - - - - - - - -
NNFDHMCK_00597 1.22e-222 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NNFDHMCK_00598 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNFDHMCK_00599 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNFDHMCK_00600 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NNFDHMCK_00601 1.25e-92 ywlG - - S - - - Belongs to the UPF0340 family
NNFDHMCK_00602 9.57e-163 - - - C - - - Oxidoreductase
NNFDHMCK_00603 1.42e-13 - - - C - - - pentaerythritol trinitrate reductase activity
NNFDHMCK_00604 5.63e-224 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNFDHMCK_00605 1.29e-90 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNFDHMCK_00606 8e-73 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
NNFDHMCK_00608 4.24e-288 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNFDHMCK_00609 7.04e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
NNFDHMCK_00610 5.08e-213 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNFDHMCK_00611 4.88e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
NNFDHMCK_00612 4.15e-47 - - - S - - - Sulfite exporter TauE/SafE
NNFDHMCK_00613 1.6e-154 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNFDHMCK_00614 4.87e-109 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNFDHMCK_00615 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNFDHMCK_00616 1.09e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNFDHMCK_00617 3.89e-27 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNFDHMCK_00618 9.35e-84 - - - S - - - Uncharacterised protein, DegV family COG1307
NNFDHMCK_00620 1.09e-68 ccl - - S - - - QueT transporter
NNFDHMCK_00621 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NNFDHMCK_00622 1.22e-128 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNFDHMCK_00623 1.18e-08 - - - S - - - peptidoglycan binding
NNFDHMCK_00626 3.36e-193 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NNFDHMCK_00627 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
NNFDHMCK_00628 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NNFDHMCK_00629 4.53e-10 - - - K - - - Helix-turn-helix XRE-family like proteins
NNFDHMCK_00636 2.39e-26 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NNFDHMCK_00637 3.72e-166 - - - S ko:K06919 - ko00000 D5 N terminal like
NNFDHMCK_00639 2.36e-120 tnp2 - - L - - - Transposase
NNFDHMCK_00640 1.95e-208 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNFDHMCK_00641 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NNFDHMCK_00642 1.14e-35 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NNFDHMCK_00643 2e-171 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NNFDHMCK_00644 1.04e-163 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNFDHMCK_00645 1.6e-47 - - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_00646 4.76e-132 - - - S ko:K07089 - ko00000 Predicted permease
NNFDHMCK_00647 1.78e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NNFDHMCK_00648 8.07e-34 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NNFDHMCK_00649 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00650 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_00651 1.13e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NNFDHMCK_00652 4.54e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
NNFDHMCK_00653 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
NNFDHMCK_00654 4.1e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNFDHMCK_00655 6.01e-60 - - - C - - - Flavodoxin
NNFDHMCK_00656 6.56e-73 yphH - - S - - - Cupin domain
NNFDHMCK_00657 5.1e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NNFDHMCK_00658 1.03e-176 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NNFDHMCK_00659 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNFDHMCK_00660 1.87e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNFDHMCK_00661 7.43e-119 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00662 3.22e-168 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NNFDHMCK_00663 2.84e-107 - - - C - - - nitroreductase
NNFDHMCK_00664 3.23e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNFDHMCK_00665 3.07e-307 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NNFDHMCK_00666 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNFDHMCK_00667 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNFDHMCK_00668 2.47e-185 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNFDHMCK_00669 3.67e-172 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNFDHMCK_00670 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
NNFDHMCK_00671 8.14e-40 ypmB - - S - - - Protein conserved in bacteria
NNFDHMCK_00672 9.06e-181 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNFDHMCK_00673 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NNFDHMCK_00674 3.26e-07 - - - - - - - -
NNFDHMCK_00675 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NNFDHMCK_00676 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNFDHMCK_00677 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NNFDHMCK_00678 1.2e-208 eriC - - P ko:K03281 - ko00000 chloride
NNFDHMCK_00679 3.5e-146 - - - S - - - Uncharacterised protein family (UPF0236)
NNFDHMCK_00680 4.03e-93 - - - K - - - Primase C terminal 1 (PriCT-1)
NNFDHMCK_00681 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
NNFDHMCK_00682 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNFDHMCK_00683 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNFDHMCK_00684 5.45e-268 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNFDHMCK_00685 9.9e-11 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNFDHMCK_00686 1.82e-49 - - - - - - - -
NNFDHMCK_00687 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNFDHMCK_00688 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNFDHMCK_00689 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNFDHMCK_00690 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNFDHMCK_00692 4.55e-20 - - - - - - - -
NNFDHMCK_00693 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NNFDHMCK_00694 8.11e-19 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
NNFDHMCK_00695 5.57e-77 - - - S - - - Psort location CytoplasmicMembrane, score
NNFDHMCK_00696 5.79e-95 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNFDHMCK_00697 1.47e-223 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NNFDHMCK_00698 1.85e-161 - - - - - - - -
NNFDHMCK_00699 7.19e-189 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NNFDHMCK_00700 9.15e-181 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NNFDHMCK_00701 1.5e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NNFDHMCK_00702 1.14e-79 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNFDHMCK_00703 7.45e-74 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NNFDHMCK_00704 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NNFDHMCK_00705 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNFDHMCK_00706 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNFDHMCK_00707 3.99e-154 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNFDHMCK_00708 2.76e-77 - - - L - - - Probable transposase
NNFDHMCK_00709 3.37e-27 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
NNFDHMCK_00710 1.79e-97 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
NNFDHMCK_00712 2.81e-95 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNFDHMCK_00713 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNFDHMCK_00714 2.06e-54 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNFDHMCK_00715 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
NNFDHMCK_00718 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
NNFDHMCK_00719 6.67e-43 - - - P - - - Heavy-metal-associated domain
NNFDHMCK_00720 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNFDHMCK_00721 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNFDHMCK_00722 1.75e-161 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
NNFDHMCK_00723 7.24e-121 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NNFDHMCK_00724 5.94e-16 - - - L ko:K07498 - ko00000 Transposase
NNFDHMCK_00725 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNFDHMCK_00726 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NNFDHMCK_00727 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NNFDHMCK_00728 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NNFDHMCK_00729 7.08e-170 - - - M - - - Rib/alpha-like repeat
NNFDHMCK_00730 3.47e-109 - - - M - - - Rib/alpha-like repeat
NNFDHMCK_00731 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NNFDHMCK_00732 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
NNFDHMCK_00733 1.17e-52 - - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_00734 9.46e-40 - - - S - - - Enterocin A Immunity
NNFDHMCK_00735 5.18e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NNFDHMCK_00736 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NNFDHMCK_00737 3.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NNFDHMCK_00738 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNFDHMCK_00739 1.38e-195 yacL - - S - - - domain protein
NNFDHMCK_00740 1.05e-312 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNFDHMCK_00741 2.26e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNFDHMCK_00742 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNFDHMCK_00743 1.88e-138 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNFDHMCK_00744 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NNFDHMCK_00745 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNFDHMCK_00746 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNFDHMCK_00747 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNFDHMCK_00748 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNFDHMCK_00749 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNFDHMCK_00750 9.49e-122 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NNFDHMCK_00751 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNFDHMCK_00752 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNFDHMCK_00753 3.44e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNFDHMCK_00754 1.24e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NNFDHMCK_00755 1.49e-11 - - - E - - - Amino acid permease
NNFDHMCK_00756 1.44e-142 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNFDHMCK_00757 1.13e-277 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
NNFDHMCK_00758 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
NNFDHMCK_00759 5.28e-264 - - - K - - - DNA binding
NNFDHMCK_00760 0.0 - - - L - - - helicase activity
NNFDHMCK_00761 3.05e-132 - - - S - - - Domain of unknown function (DUF4343)
NNFDHMCK_00762 1.05e-74 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
NNFDHMCK_00763 3.12e-57 - - - S - - - Domain of unknown function (DUF3841)
NNFDHMCK_00764 3.88e-245 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
NNFDHMCK_00765 1.27e-210 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NNFDHMCK_00766 1.91e-88 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNFDHMCK_00767 1.74e-133 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
NNFDHMCK_00769 1.19e-96 - - - S ko:K06919 - ko00000 DNA primase
NNFDHMCK_00770 1.13e-22 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NNFDHMCK_00771 3.4e-119 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NNFDHMCK_00772 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
NNFDHMCK_00773 8.2e-235 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NNFDHMCK_00774 7.01e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NNFDHMCK_00775 5.49e-150 - - - M - - - Core-2/I-Branching enzyme
NNFDHMCK_00776 3.98e-114 epsE2 - - M - - - Bacterial sugar transferase
NNFDHMCK_00777 1.29e-161 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNFDHMCK_00778 5.99e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NNFDHMCK_00779 2.68e-116 ywqD - - D - - - Capsular exopolysaccharide family
NNFDHMCK_00780 5.82e-93 epsB - - M - - - biosynthesis protein
NNFDHMCK_00782 4.77e-72 - - - - - - - -
NNFDHMCK_00783 4.29e-115 yunF - - F - - - Protein of unknown function DUF72
NNFDHMCK_00784 3.45e-198 yngD - - S ko:K07097 - ko00000 DHHA1 domain
NNFDHMCK_00785 1.8e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NNFDHMCK_00786 1.17e-74 - - - - - - - -
NNFDHMCK_00787 1.56e-93 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNFDHMCK_00788 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNFDHMCK_00789 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNFDHMCK_00790 1.48e-284 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNFDHMCK_00791 8.89e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNFDHMCK_00792 1.44e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
NNFDHMCK_00793 6.81e-103 - - - S - - - L,D-transpeptidase catalytic domain
NNFDHMCK_00794 2.34e-27 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNFDHMCK_00795 2.22e-114 - - - M - - - transferase activity, transferring glycosyl groups
NNFDHMCK_00796 5.46e-58 cps3I - - G - - - Acyltransferase family
NNFDHMCK_00797 5.48e-188 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NNFDHMCK_00798 6.39e-69 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NNFDHMCK_00799 8.36e-196 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NNFDHMCK_00800 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNFDHMCK_00803 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNFDHMCK_00804 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NNFDHMCK_00805 1.5e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNFDHMCK_00808 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NNFDHMCK_00809 9.49e-122 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNFDHMCK_00810 4.93e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNFDHMCK_00811 1.17e-23 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NNFDHMCK_00812 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NNFDHMCK_00813 3.71e-37 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NNFDHMCK_00814 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNFDHMCK_00815 4.54e-87 ybbR - - S - - - YbbR-like protein
NNFDHMCK_00816 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNFDHMCK_00818 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NNFDHMCK_00819 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNFDHMCK_00820 1.12e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNFDHMCK_00821 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNFDHMCK_00822 7.05e-151 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNFDHMCK_00824 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NNFDHMCK_00825 1.48e-139 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NNFDHMCK_00826 1.73e-129 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NNFDHMCK_00827 1.9e-159 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNFDHMCK_00828 5.08e-275 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NNFDHMCK_00829 7.97e-85 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNFDHMCK_00830 9.49e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNFDHMCK_00831 3.77e-83 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNFDHMCK_00832 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNFDHMCK_00833 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNFDHMCK_00834 6.01e-55 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NNFDHMCK_00835 6.22e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NNFDHMCK_00836 1.52e-97 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNFDHMCK_00838 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NNFDHMCK_00839 1.01e-171 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NNFDHMCK_00840 1.23e-90 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNFDHMCK_00841 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNFDHMCK_00842 1.49e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NNFDHMCK_00843 5.31e-72 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
NNFDHMCK_00844 1.27e-104 lysR5 - - K - - - LysR substrate binding domain
NNFDHMCK_00845 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
NNFDHMCK_00846 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
NNFDHMCK_00847 6.86e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNFDHMCK_00850 1.61e-146 - - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_00851 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNFDHMCK_00852 5.54e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
NNFDHMCK_00853 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNFDHMCK_00854 7.54e-206 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNFDHMCK_00855 3.12e-79 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NNFDHMCK_00856 6.52e-233 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNFDHMCK_00857 1.54e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNFDHMCK_00858 8.06e-109 csrR - - K - - - response regulator
NNFDHMCK_00859 4.65e-22 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NNFDHMCK_00860 7.93e-152 icaA - - M - - - Glycosyl transferase family group 2
NNFDHMCK_00861 3.3e-52 - - - - - - - -
NNFDHMCK_00862 2.82e-110 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNFDHMCK_00864 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNFDHMCK_00865 8.89e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNFDHMCK_00866 2.24e-52 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NNFDHMCK_00867 5.61e-113 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NNFDHMCK_00868 1.32e-217 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NNFDHMCK_00869 4.73e-142 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
NNFDHMCK_00870 7.82e-189 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNFDHMCK_00871 2.59e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNFDHMCK_00872 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNFDHMCK_00873 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNFDHMCK_00874 2.56e-16 ykzG - - S - - - Belongs to the UPF0356 family
NNFDHMCK_00876 3.08e-54 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
NNFDHMCK_00879 1.78e-21 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
NNFDHMCK_00880 2.71e-128 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
NNFDHMCK_00881 6.57e-109 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
NNFDHMCK_00882 5.27e-75 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
NNFDHMCK_00883 3.76e-172 - - - S - - - interspecies interaction between organisms
NNFDHMCK_00884 2.25e-259 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
NNFDHMCK_00886 6.05e-45 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNFDHMCK_00887 6.64e-267 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNFDHMCK_00888 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NNFDHMCK_00889 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNFDHMCK_00890 3.54e-270 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNFDHMCK_00891 4.74e-130 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNFDHMCK_00892 4.54e-124 ytmP - - M - - - Choline/ethanolamine kinase
NNFDHMCK_00893 2.82e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNFDHMCK_00894 1.16e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_00895 1.1e-68 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NNFDHMCK_00897 7.01e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNFDHMCK_00898 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NNFDHMCK_00899 2.46e-122 - - - J - - - Aminoglycoside-2''-adenylyltransferase
NNFDHMCK_00900 5.22e-255 - - - L - - - transposition, DNA-mediated
NNFDHMCK_00901 2.03e-77 - - - T - - - Universal stress protein family
NNFDHMCK_00902 1.12e-144 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NNFDHMCK_00903 1.62e-61 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNFDHMCK_00904 5.17e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NNFDHMCK_00906 3.08e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
NNFDHMCK_00907 2.16e-120 baeS - - T - - - Histidine kinase
NNFDHMCK_00908 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
NNFDHMCK_00909 5.94e-148 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NNFDHMCK_00911 1.28e-80 - - - - - - - -
NNFDHMCK_00914 3.08e-204 yfhO - - S - - - Bacterial membrane protein YfhO
NNFDHMCK_00915 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNFDHMCK_00916 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NNFDHMCK_00917 1.65e-72 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NNFDHMCK_00918 8.59e-21 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NNFDHMCK_00919 1.24e-43 - - - K - - - MerR HTH family regulatory protein
NNFDHMCK_00920 9.06e-52 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNFDHMCK_00921 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NNFDHMCK_00922 9.7e-84 icaB - - G - - - Polysaccharide deacetylase
NNFDHMCK_00924 4.07e-41 - - - K - - - LysR substrate binding domain
NNFDHMCK_00925 6.11e-51 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NNFDHMCK_00926 3.83e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNFDHMCK_00927 2.35e-08 - - - - - - - -
NNFDHMCK_00928 1.35e-270 potE - - E - - - Amino Acid
NNFDHMCK_00929 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NNFDHMCK_00931 1.97e-102 - - - F - - - Hydrolase, nudix family
NNFDHMCK_00932 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNFDHMCK_00933 3.13e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNFDHMCK_00934 2.15e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNFDHMCK_00935 9.06e-152 ytbE - - S - - - reductase
NNFDHMCK_00936 8.21e-56 - - - K - - - HxlR-like helix-turn-helix
NNFDHMCK_00937 8.18e-310 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NNFDHMCK_00938 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNFDHMCK_00939 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NNFDHMCK_00940 1.33e-109 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNFDHMCK_00941 1.08e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNFDHMCK_00942 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNFDHMCK_00943 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NNFDHMCK_00944 3.3e-236 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNFDHMCK_00945 9.86e-105 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NNFDHMCK_00946 3.93e-87 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NNFDHMCK_00947 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
NNFDHMCK_00948 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NNFDHMCK_00949 1.1e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NNFDHMCK_00950 4.16e-259 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNFDHMCK_00951 1.63e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNFDHMCK_00952 7.25e-32 - - - G - - - Xylose isomerase domain protein TIM barrel
NNFDHMCK_00953 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
NNFDHMCK_00954 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNFDHMCK_00955 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNFDHMCK_00956 2.12e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
NNFDHMCK_00957 2.26e-59 ykuL - - S - - - CBS domain
NNFDHMCK_00958 2.43e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNFDHMCK_00959 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNFDHMCK_00960 1.15e-102 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NNFDHMCK_00963 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNFDHMCK_00964 2.16e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNFDHMCK_00965 1.8e-67 - - - M - - - LysM domain protein
NNFDHMCK_00966 4.52e-115 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NNFDHMCK_00967 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
NNFDHMCK_00969 5.61e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
NNFDHMCK_00970 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNFDHMCK_00971 4.4e-115 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNFDHMCK_00972 9.06e-233 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NNFDHMCK_00973 1.52e-288 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNFDHMCK_00974 1.21e-136 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNFDHMCK_00975 3.51e-61 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNFDHMCK_00976 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNFDHMCK_00977 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNFDHMCK_00978 1.54e-223 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNFDHMCK_00979 1.37e-65 - - - L - - - Protein involved in initiation of plasmid replication
NNFDHMCK_00980 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNFDHMCK_00981 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNFDHMCK_00982 5.56e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
NNFDHMCK_00983 1.02e-86 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NNFDHMCK_00985 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
NNFDHMCK_00986 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NNFDHMCK_00987 8.75e-60 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NNFDHMCK_00988 3.21e-68 - - - K - - - Transcriptional regulator C-terminal region
NNFDHMCK_00989 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
NNFDHMCK_00990 1.17e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NNFDHMCK_00991 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNFDHMCK_00997 1.25e-73 - - - V - - - endonuclease activity
NNFDHMCK_01000 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NNFDHMCK_01001 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NNFDHMCK_01002 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NNFDHMCK_01003 1.21e-20 - - - - - - - -
NNFDHMCK_01005 6.87e-90 - - - - - - - -
NNFDHMCK_01006 1.12e-123 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNFDHMCK_01007 3.83e-226 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NNFDHMCK_01008 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NNFDHMCK_01009 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNFDHMCK_01010 8.18e-273 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNFDHMCK_01011 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNFDHMCK_01012 7.88e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNFDHMCK_01013 1.09e-78 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNFDHMCK_01014 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNFDHMCK_01015 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNFDHMCK_01016 5.73e-68 - - - S - - - Protein of unknown function (DUF441)
NNFDHMCK_01017 8.77e-159 yitL - - S ko:K00243 - ko00000 S1 domain
NNFDHMCK_01018 1.58e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NNFDHMCK_01019 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NNFDHMCK_01020 3.18e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NNFDHMCK_01021 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
NNFDHMCK_01022 1.86e-103 - - - H - - - Nodulation protein S (NodS)
NNFDHMCK_01023 4.81e-66 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNFDHMCK_01024 3.44e-91 yqeK - - H - - - Hydrolase, HD family
NNFDHMCK_01025 1.43e-98 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNFDHMCK_01026 1.36e-40 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NNFDHMCK_01027 2.41e-228 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NNFDHMCK_01028 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NNFDHMCK_01029 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNFDHMCK_01030 7.67e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NNFDHMCK_01031 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNFDHMCK_01032 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNFDHMCK_01033 4.01e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NNFDHMCK_01034 1.28e-12 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NNFDHMCK_01035 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNFDHMCK_01036 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNFDHMCK_01040 4.39e-81 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NNFDHMCK_01041 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNFDHMCK_01042 1.05e-13 ftsL - - D - - - Essential cell division protein
NNFDHMCK_01043 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNFDHMCK_01044 2.1e-171 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNFDHMCK_01045 1.27e-234 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNFDHMCK_01046 2.13e-118 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNFDHMCK_01047 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NNFDHMCK_01048 1.14e-84 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
NNFDHMCK_01049 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
NNFDHMCK_01050 8.38e-92 - - - S - - - An automated process has identified a potential problem with this gene model
NNFDHMCK_01051 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
NNFDHMCK_01052 2.59e-183 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
NNFDHMCK_01053 6.67e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NNFDHMCK_01054 2.72e-33 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNFDHMCK_01055 8.61e-67 - - - C - - - Oxidoreductase NAD-binding domain
NNFDHMCK_01056 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NNFDHMCK_01057 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
NNFDHMCK_01058 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNFDHMCK_01059 4.02e-116 yhgE - - V ko:K01421 - ko00000 domain protein
NNFDHMCK_01060 9.94e-58 - - - S - - - zinc-ribbon domain
NNFDHMCK_01061 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NNFDHMCK_01062 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNFDHMCK_01063 2.33e-14 yulB - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNFDHMCK_01064 3.15e-127 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
NNFDHMCK_01065 7.61e-10 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NNFDHMCK_01066 5.52e-64 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NNFDHMCK_01067 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NNFDHMCK_01068 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NNFDHMCK_01069 7.37e-174 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NNFDHMCK_01070 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NNFDHMCK_01071 1.54e-80 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
NNFDHMCK_01072 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NNFDHMCK_01073 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NNFDHMCK_01074 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNFDHMCK_01076 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NNFDHMCK_01077 1.29e-215 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNFDHMCK_01078 2.34e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
NNFDHMCK_01079 4.37e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NNFDHMCK_01080 4.71e-60 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NNFDHMCK_01082 3.61e-30 - - - M - - - family 8
NNFDHMCK_01083 3.38e-110 - - - S - - - Sulfite exporter TauE/SafE
NNFDHMCK_01084 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNFDHMCK_01085 1.52e-171 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNFDHMCK_01086 5.26e-298 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NNFDHMCK_01087 3.17e-174 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNFDHMCK_01088 2.48e-125 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNFDHMCK_01089 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNFDHMCK_01090 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NNFDHMCK_01091 3.53e-94 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NNFDHMCK_01092 1.5e-61 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNFDHMCK_01093 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NNFDHMCK_01094 1.4e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNFDHMCK_01095 3.86e-59 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NNFDHMCK_01096 9.69e-90 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NNFDHMCK_01097 2.21e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01098 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNFDHMCK_01099 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NNFDHMCK_01100 9.6e-241 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNFDHMCK_01101 3.79e-254 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNFDHMCK_01102 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
NNFDHMCK_01103 1.22e-238 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNFDHMCK_01104 1.18e-138 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NNFDHMCK_01105 7.58e-252 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NNFDHMCK_01106 9.59e-104 - - - S - - - Putative threonine/serine exporter
NNFDHMCK_01107 1.97e-64 - - - S - - - Threonine/Serine exporter, ThrE
NNFDHMCK_01108 2.76e-129 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NNFDHMCK_01109 1.33e-198 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNFDHMCK_01110 6.85e-39 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NNFDHMCK_01111 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNFDHMCK_01112 8.4e-160 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NNFDHMCK_01113 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NNFDHMCK_01114 5.37e-279 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NNFDHMCK_01115 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NNFDHMCK_01116 2.52e-17 - - - - - - - -
NNFDHMCK_01118 2.2e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNFDHMCK_01119 4.07e-213 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNFDHMCK_01120 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NNFDHMCK_01121 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NNFDHMCK_01122 8.09e-73 - - - V - - - Type II restriction enzyme, methylase subunits
NNFDHMCK_01123 6.58e-72 pgm - - G - - - Phosphoglycerate mutase family
NNFDHMCK_01124 5.21e-55 - - - S - - - repeat protein
NNFDHMCK_01125 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNFDHMCK_01126 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NNFDHMCK_01127 1.06e-153 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NNFDHMCK_01128 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNFDHMCK_01130 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NNFDHMCK_01131 1.4e-92 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NNFDHMCK_01132 1.49e-31 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNFDHMCK_01133 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNFDHMCK_01134 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NNFDHMCK_01135 2.04e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NNFDHMCK_01136 3.97e-69 gtcA - - S - - - Teichoic acid glycosylation protein
NNFDHMCK_01137 7.86e-177 - - - E - - - amino acid
NNFDHMCK_01138 1.28e-171 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNFDHMCK_01139 1.43e-152 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
NNFDHMCK_01141 9.29e-75 - - - K - - - Domain of unknown function (DUF1836)
NNFDHMCK_01143 4.37e-276 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNFDHMCK_01144 1.98e-22 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NNFDHMCK_01145 2.57e-191 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NNFDHMCK_01146 2.74e-39 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNFDHMCK_01147 2.34e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNFDHMCK_01148 5.79e-84 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NNFDHMCK_01149 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNFDHMCK_01153 9.33e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNFDHMCK_01154 5.21e-269 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNFDHMCK_01155 3.27e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NNFDHMCK_01156 1.68e-187 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NNFDHMCK_01157 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
NNFDHMCK_01158 1.09e-21 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01159 1.83e-41 - - - - - - - -
NNFDHMCK_01160 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NNFDHMCK_01161 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
NNFDHMCK_01162 1.82e-19 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NNFDHMCK_01163 1.07e-214 potE2 - - E ko:K03294 - ko00000 amino acid
NNFDHMCK_01167 1.84e-130 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNFDHMCK_01168 1.61e-90 - - - O - - - ADP-ribosylglycohydrolase
NNFDHMCK_01170 7.53e-64 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
NNFDHMCK_01171 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NNFDHMCK_01172 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNFDHMCK_01173 5.27e-101 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNFDHMCK_01174 6.79e-39 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNFDHMCK_01175 4e-153 yebC - - K - - - Transcriptional regulatory protein
NNFDHMCK_01176 2.33e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNFDHMCK_01177 1.83e-151 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NNFDHMCK_01178 1.12e-15 - - - M - - - Lysin motif
NNFDHMCK_01179 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NNFDHMCK_01180 4.22e-106 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
NNFDHMCK_01181 7.2e-13 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNFDHMCK_01182 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01183 1.93e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNFDHMCK_01184 7.15e-72 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNFDHMCK_01185 1.55e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NNFDHMCK_01186 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
NNFDHMCK_01187 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NNFDHMCK_01188 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NNFDHMCK_01189 1.71e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNFDHMCK_01190 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
NNFDHMCK_01191 2.6e-106 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NNFDHMCK_01192 4.34e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NNFDHMCK_01193 1.44e-179 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNFDHMCK_01194 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNFDHMCK_01195 2.28e-283 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNFDHMCK_01196 3.29e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNFDHMCK_01198 8.2e-105 - - - S - - - overlaps another CDS with the same product name
NNFDHMCK_01199 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NNFDHMCK_01200 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNFDHMCK_01201 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
NNFDHMCK_01202 1.65e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNFDHMCK_01203 2.65e-112 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNFDHMCK_01210 7.39e-143 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NNFDHMCK_01211 1.84e-78 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNFDHMCK_01212 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNFDHMCK_01213 3.4e-77 - - - - - - - -
NNFDHMCK_01214 7.02e-09 - - - S - - - YSIRK type signal peptide
NNFDHMCK_01217 5.76e-07 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
NNFDHMCK_01218 8.93e-16 - - - K - - - Transcriptional regulator
NNFDHMCK_01219 1.31e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NNFDHMCK_01221 3.93e-27 - - - K - - - LytTr DNA-binding domain
NNFDHMCK_01222 3.9e-67 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNFDHMCK_01223 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NNFDHMCK_01226 9.21e-45 - - - S - - - Protein of unknown function (DUF4256)
NNFDHMCK_01227 8.86e-239 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNFDHMCK_01230 6.29e-127 cadD - - P - - - Cadmium resistance transporter
NNFDHMCK_01231 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NNFDHMCK_01232 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNFDHMCK_01234 5.76e-12 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
NNFDHMCK_01235 5.87e-13 - - - D - - - Antitoxin Phd_YefM, type II toxin-antitoxin system
NNFDHMCK_01236 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
NNFDHMCK_01238 2.2e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01239 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
NNFDHMCK_01240 6.98e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NNFDHMCK_01241 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNFDHMCK_01242 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NNFDHMCK_01243 6.4e-138 - - - P - - - Integral membrane protein TerC family
NNFDHMCK_01244 3.75e-49 - - - K - - - Transcriptional regulator
NNFDHMCK_01245 6.78e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NNFDHMCK_01246 4.1e-128 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01247 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNFDHMCK_01249 4.5e-23 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
NNFDHMCK_01250 8.29e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNFDHMCK_01251 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNFDHMCK_01252 7.68e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NNFDHMCK_01253 6.59e-219 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NNFDHMCK_01254 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNFDHMCK_01255 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NNFDHMCK_01256 1.4e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NNFDHMCK_01257 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NNFDHMCK_01258 3.63e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NNFDHMCK_01259 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_01260 6.79e-263 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NNFDHMCK_01262 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NNFDHMCK_01263 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NNFDHMCK_01264 2.17e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NNFDHMCK_01265 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NNFDHMCK_01266 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NNFDHMCK_01267 1.13e-278 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNFDHMCK_01268 7.5e-279 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNFDHMCK_01269 7.76e-115 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NNFDHMCK_01270 3.49e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNFDHMCK_01271 2.29e-75 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NNFDHMCK_01272 2.74e-145 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NNFDHMCK_01274 2.89e-26 - - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_01275 4.79e-217 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNFDHMCK_01276 2.24e-68 coiA - - S ko:K06198 - ko00000 Competence protein
NNFDHMCK_01277 3.19e-39 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNFDHMCK_01278 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNFDHMCK_01279 2.13e-100 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NNFDHMCK_01280 1.85e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNFDHMCK_01281 9.75e-154 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NNFDHMCK_01282 4.3e-83 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NNFDHMCK_01283 2.84e-95 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
NNFDHMCK_01287 8.09e-51 - - - K - - - Peptidase S24-like
NNFDHMCK_01288 5.16e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NNFDHMCK_01289 2.91e-53 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NNFDHMCK_01290 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NNFDHMCK_01291 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NNFDHMCK_01292 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
NNFDHMCK_01293 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNFDHMCK_01295 2.78e-32 radC - - L ko:K03630 - ko00000 DNA repair protein
NNFDHMCK_01297 6.62e-143 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNFDHMCK_01298 5.17e-80 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNFDHMCK_01299 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNFDHMCK_01300 1.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
NNFDHMCK_01301 9.51e-31 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNFDHMCK_01302 2.7e-72 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNFDHMCK_01303 8.34e-132 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNFDHMCK_01304 2.01e-110 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NNFDHMCK_01306 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNFDHMCK_01307 1.55e-217 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NNFDHMCK_01308 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NNFDHMCK_01309 2.26e-93 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNFDHMCK_01310 4.78e-189 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NNFDHMCK_01311 2.94e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NNFDHMCK_01312 1.37e-40 - - - S - - - YjbR
NNFDHMCK_01313 3.35e-100 yycI - - S - - - YycH protein
NNFDHMCK_01314 1.07e-125 yycH - - S - - - YycH protein
NNFDHMCK_01315 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNFDHMCK_01316 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNFDHMCK_01318 2.01e-185 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NNFDHMCK_01319 1.5e-218 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NNFDHMCK_01321 4.07e-135 yxeH - - S - - - hydrolase
NNFDHMCK_01323 3.13e-105 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
NNFDHMCK_01325 4.52e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NNFDHMCK_01326 4.3e-91 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01328 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NNFDHMCK_01329 2.27e-15 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
NNFDHMCK_01330 9.68e-126 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNFDHMCK_01331 9.09e-24 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNFDHMCK_01332 1.38e-119 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NNFDHMCK_01333 6.62e-35 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NNFDHMCK_01334 1.5e-40 ynzC - - S - - - UPF0291 protein
NNFDHMCK_01340 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NNFDHMCK_01341 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNFDHMCK_01342 7.57e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNFDHMCK_01343 1.01e-100 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNFDHMCK_01344 6.84e-232 yhdP - - S - - - Transporter associated domain
NNFDHMCK_01347 4.79e-53 - - - L - - - DnaD domain protein
NNFDHMCK_01350 2.16e-10 - - - - - - - -
NNFDHMCK_01351 7.04e-118 - - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_01352 4.52e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNFDHMCK_01353 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNFDHMCK_01354 4.56e-256 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNFDHMCK_01355 1.36e-71 - - - EGP - - - Transmembrane secretion effector
NNFDHMCK_01359 3.19e-59 tnpR1 - - L - - - Resolvase, N terminal domain
NNFDHMCK_01360 7.02e-66 - - - S - - - Filamentation induced by cAMP protein fic
NNFDHMCK_01361 3.42e-135 - - - K - - - Psort location CytoplasmicMembrane, score
NNFDHMCK_01362 2.02e-216 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNFDHMCK_01363 1.16e-162 - - - S ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNFDHMCK_01364 2.21e-09 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NNFDHMCK_01365 2.26e-06 - - CBM50 MNU ko:K02395,ko:K19220,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNFDHMCK_01366 5.61e-108 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NNFDHMCK_01367 9.69e-38 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NNFDHMCK_01368 4.49e-69 - - - L - - - Phage integrase, N-terminal SAM-like domain
NNFDHMCK_01370 1.48e-64 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNFDHMCK_01373 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NNFDHMCK_01374 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNFDHMCK_01375 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NNFDHMCK_01376 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NNFDHMCK_01377 3.57e-33 yktA - - S - - - Belongs to the UPF0223 family
NNFDHMCK_01378 2.53e-21 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNFDHMCK_01379 5.94e-253 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NNFDHMCK_01380 5.32e-200 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NNFDHMCK_01381 2.39e-80 - - - L - - - Belongs to the 'phage' integrase family
NNFDHMCK_01382 1.91e-17 - - - S - - - Acyltransferase family
NNFDHMCK_01383 1.38e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNFDHMCK_01384 7.02e-157 - - - K - - - LysR substrate binding domain
NNFDHMCK_01386 6.94e-28 - - - - - - - -
NNFDHMCK_01387 7.47e-72 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NNFDHMCK_01388 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NNFDHMCK_01389 7.31e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NNFDHMCK_01390 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NNFDHMCK_01391 4.82e-68 repB - - L - - - Initiator Replication protein
NNFDHMCK_01392 3.82e-21 XK26_06135 - - D - - - Plasmid recombination enzyme
NNFDHMCK_01393 3.15e-311 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
NNFDHMCK_01394 0.0 XK27_03330 - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
NNFDHMCK_01395 3.84e-237 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NNFDHMCK_01396 3.56e-98 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNFDHMCK_01397 9.34e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NNFDHMCK_01398 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NNFDHMCK_01399 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NNFDHMCK_01400 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
NNFDHMCK_01401 3.74e-101 radC - - L ko:K03630 - ko00000 DNA repair protein
NNFDHMCK_01402 8.51e-170 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NNFDHMCK_01403 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNFDHMCK_01404 1.01e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNFDHMCK_01405 1.68e-203 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNFDHMCK_01406 2.45e-225 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNFDHMCK_01408 1.1e-30 - - - S - - - Cytochrome B5
NNFDHMCK_01409 3.44e-54 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNFDHMCK_01410 1.82e-206 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNFDHMCK_01411 2.57e-135 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NNFDHMCK_01412 1.06e-84 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NNFDHMCK_01413 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNFDHMCK_01414 1.82e-186 ymfH - - S - - - Peptidase M16
NNFDHMCK_01415 1.04e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
NNFDHMCK_01416 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NNFDHMCK_01417 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NNFDHMCK_01418 6.24e-84 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NNFDHMCK_01419 2.46e-23 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNFDHMCK_01420 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNFDHMCK_01421 4.39e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNFDHMCK_01422 3.64e-153 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NNFDHMCK_01423 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNFDHMCK_01424 2.67e-92 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNFDHMCK_01425 1.39e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NNFDHMCK_01426 2.23e-53 ywnA - - K - - - Transcriptional regulator
NNFDHMCK_01427 6.27e-41 - - - S - - - CHY zinc finger
NNFDHMCK_01428 8.67e-105 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NNFDHMCK_01430 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
NNFDHMCK_01431 8.23e-30 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NNFDHMCK_01433 7.88e-52 - - - M - - - Acetyltransferase (GNAT) family
NNFDHMCK_01434 6e-08 - - - M - - - Glycosyltransferase group 2 family protein
NNFDHMCK_01435 2.15e-36 cpsJ - - M - - - Glycosyltransferase group 2 family protein
NNFDHMCK_01436 5.36e-234 - - - L - - - Probable transposase
NNFDHMCK_01437 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
NNFDHMCK_01438 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNFDHMCK_01439 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNFDHMCK_01440 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
NNFDHMCK_01441 9.26e-188 - - - S ko:K07112 - ko00000 Sulphur transport
NNFDHMCK_01442 4.12e-125 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
NNFDHMCK_01443 1.33e-236 - - - C - - - RnfC Barrel sandwich hybrid domain
NNFDHMCK_01444 7.55e-38 - - - S - - - Iron-sulfur cluster assembly protein
NNFDHMCK_01445 1.82e-21 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NNFDHMCK_01447 0.0 - - - L - - - DNA helicase
NNFDHMCK_01448 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNFDHMCK_01449 2.31e-216 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNFDHMCK_01450 1.6e-128 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NNFDHMCK_01451 1.19e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNFDHMCK_01452 9.06e-131 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNFDHMCK_01453 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_01454 5.94e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
NNFDHMCK_01455 2.66e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNFDHMCK_01456 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
NNFDHMCK_01457 2.12e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNFDHMCK_01458 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNFDHMCK_01459 2.98e-131 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NNFDHMCK_01460 2.21e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNFDHMCK_01461 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNFDHMCK_01462 1.01e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NNFDHMCK_01463 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NNFDHMCK_01464 7.96e-68 - - - S - - - Domain of unknown function (DUF956)
NNFDHMCK_01465 4.25e-92 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NNFDHMCK_01466 4.1e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNFDHMCK_01467 1.19e-208 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNFDHMCK_01468 1.36e-96 ung2 - - L - - - Uracil-DNA glycosylase
NNFDHMCK_01469 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NNFDHMCK_01470 1.2e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NNFDHMCK_01471 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NNFDHMCK_01472 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NNFDHMCK_01473 3.27e-57 cps3F - - - - - - -
NNFDHMCK_01474 2.22e-108 - - - S - - - Membrane
NNFDHMCK_01475 0.0 - - - E - - - Amino acid permease
NNFDHMCK_01476 3.6e-293 cadA - - P - - - P-type ATPase
NNFDHMCK_01477 2.47e-146 degV - - S - - - EDD domain protein, DegV family
NNFDHMCK_01478 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NNFDHMCK_01479 1.68e-69 - - - F - - - Glutamine amidotransferase class-I
NNFDHMCK_01480 5.97e-22 yuxO - - Q - - - Thioesterase superfamily
NNFDHMCK_01481 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNFDHMCK_01482 1.27e-180 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
NNFDHMCK_01483 7.95e-90 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNFDHMCK_01484 8.49e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNFDHMCK_01485 3.42e-270 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNFDHMCK_01486 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNFDHMCK_01487 7.4e-177 - - - G - - - Xylose isomerase-like TIM barrel
NNFDHMCK_01488 6.52e-90 - - - K - - - Transcriptional regulator, LysR family
NNFDHMCK_01489 2.48e-123 - - - EGP - - - Major Facilitator Superfamily
NNFDHMCK_01490 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
NNFDHMCK_01491 8.15e-63 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic
NNFDHMCK_01493 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NNFDHMCK_01494 5.76e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNFDHMCK_01495 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNFDHMCK_01496 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NNFDHMCK_01497 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
NNFDHMCK_01498 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNFDHMCK_01499 9.01e-57 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Pts system
NNFDHMCK_01500 2.9e-114 nanK - - GK - - - ROK family
NNFDHMCK_01501 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NNFDHMCK_01502 4.39e-143 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NNFDHMCK_01503 3.51e-28 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NNFDHMCK_01504 2.84e-83 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNFDHMCK_01505 3.41e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNFDHMCK_01506 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NNFDHMCK_01507 7.52e-100 - - - L - - - Replication protein
NNFDHMCK_01508 0.000187 - - - - - - - -
NNFDHMCK_01514 6.29e-100 - - - S - - - Siphovirus Gp157
NNFDHMCK_01515 7.97e-308 - - - L - - - Helicase C-terminal domain protein
NNFDHMCK_01516 3.09e-149 - - - L - - - AAA domain
NNFDHMCK_01517 2.44e-110 - - - - - - - -
NNFDHMCK_01518 1.28e-180 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NNFDHMCK_01519 1.05e-291 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NNFDHMCK_01520 2.99e-65 - - - S - - - VRR_NUC
NNFDHMCK_01524 2.57e-42 - - - S - - - Phage transcriptional regulator, ArpU family
NNFDHMCK_01525 2.63e-08 - - - T - - - SpoVT / AbrB like domain
NNFDHMCK_01526 7.48e-23 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NNFDHMCK_01529 4.73e-116 - - - L - - - HNH nucleases
NNFDHMCK_01530 1.05e-107 - - - L - - - Phage terminase, small subunit
NNFDHMCK_01531 0.0 - - - S - - - Phage Terminase
NNFDHMCK_01533 9.49e-262 - - - S - - - Phage portal protein
NNFDHMCK_01534 1.04e-152 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NNFDHMCK_01535 3.71e-280 - - - S - - - Phage capsid family
NNFDHMCK_01536 3.09e-29 - - - S - - - Phage gp6-like head-tail connector protein
NNFDHMCK_01537 2.22e-78 - - - S - - - Phage head-tail joining protein
NNFDHMCK_01538 2.78e-85 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNFDHMCK_01539 1.77e-85 - - - S - - - Protein of unknown function (DUF806)
NNFDHMCK_01540 2.11e-156 - - - S - - - Phage tail tube protein
NNFDHMCK_01541 1.36e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
NNFDHMCK_01543 0.0 - - - L - - - Phage tail tape measure protein TP901
NNFDHMCK_01544 2.97e-184 - - - S - - - Phage tail protein
NNFDHMCK_01545 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
NNFDHMCK_01546 5.89e-122 - - - M - - - Prophage endopeptidase tail
NNFDHMCK_01548 9.84e-30 - - - S - - - Calcineurin-like phosphoesterase
NNFDHMCK_01549 3.41e-05 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Pectinesterase
NNFDHMCK_01554 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNFDHMCK_01555 1.07e-236 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNFDHMCK_01556 5.59e-84 ypsA - - S - - - Belongs to the UPF0398 family
NNFDHMCK_01557 1.13e-243 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NNFDHMCK_01559 5.53e-44 - - - M - - - GNAT acetyltransferase
NNFDHMCK_01560 3.9e-21 - - - M - - - GNAT acetyltransferase
NNFDHMCK_01561 7.2e-29 yheA - - S - - - Belongs to the UPF0342 family
NNFDHMCK_01562 5.38e-283 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNFDHMCK_01563 2.01e-199 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NNFDHMCK_01564 6.13e-212 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NNFDHMCK_01565 6.36e-229 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNFDHMCK_01566 4.36e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NNFDHMCK_01567 9.52e-187 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NNFDHMCK_01568 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
NNFDHMCK_01569 1.55e-184 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NNFDHMCK_01570 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NNFDHMCK_01571 1.42e-276 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NNFDHMCK_01572 2.26e-141 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NNFDHMCK_01573 3.64e-189 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNFDHMCK_01574 5.23e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNFDHMCK_01575 5.27e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNFDHMCK_01576 5.52e-111 - - - S - - - Alpha beta hydrolase
NNFDHMCK_01577 1.32e-57 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNFDHMCK_01578 2.8e-174 - - - V - - - MatE
NNFDHMCK_01579 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NNFDHMCK_01580 5.65e-92 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNFDHMCK_01581 2.78e-126 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NNFDHMCK_01582 1.53e-127 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NNFDHMCK_01583 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01584 2.88e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
NNFDHMCK_01585 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNFDHMCK_01587 8.73e-51 - - - - - - - -
NNFDHMCK_01588 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NNFDHMCK_01589 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNFDHMCK_01590 1.57e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNFDHMCK_01591 2.73e-110 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNFDHMCK_01592 1.17e-152 - - - S - - - Conserved hypothetical protein 698
NNFDHMCK_01593 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NNFDHMCK_01594 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNFDHMCK_01595 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNFDHMCK_01596 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NNFDHMCK_01597 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNFDHMCK_01598 1.27e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNFDHMCK_01599 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NNFDHMCK_01600 5.91e-194 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNFDHMCK_01601 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNFDHMCK_01602 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNFDHMCK_01603 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NNFDHMCK_01604 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNFDHMCK_01605 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNFDHMCK_01606 1.23e-139 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NNFDHMCK_01607 6.63e-148 - - - S - - - Glycosyl transferase family 2
NNFDHMCK_01608 9.12e-81 - - - D - - - peptidase
NNFDHMCK_01609 1.03e-49 - - - S - - - Conjugative transposon protein TcpC
NNFDHMCK_01610 3.88e-76 - - - S - - - Conjugative transposon protein TcpC
NNFDHMCK_01611 3.21e-243 - - - M - - - NlpC p60 family protein
NNFDHMCK_01612 5.33e-215 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NNFDHMCK_01613 4.78e-94 - - - L - - - Lactococcus lactis RepB C-terminus
NNFDHMCK_01614 3.38e-81 - - - M - - - LPXTG-motif cell wall anchor domain protein
NNFDHMCK_01615 1.96e-54 - - - - - - - -
NNFDHMCK_01616 1.32e-41 - - - K - - - GNAT family
NNFDHMCK_01617 5.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNFDHMCK_01618 5.08e-278 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NNFDHMCK_01619 1.47e-45 - - - O - - - ADP-ribosylglycohydrolase
NNFDHMCK_01620 2.53e-273 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNFDHMCK_01621 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NNFDHMCK_01622 2.38e-209 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NNFDHMCK_01623 7.84e-157 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NNFDHMCK_01624 7.79e-245 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NNFDHMCK_01625 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NNFDHMCK_01626 9.89e-215 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNFDHMCK_01627 1.13e-32 - - - S - - - Domain of unknown function (DUF4828)
NNFDHMCK_01628 3.86e-188 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NNFDHMCK_01630 4.53e-07 - - - L - - - hmm pf01527
NNFDHMCK_01632 3.34e-11 - - - L - - - HTH-like domain
NNFDHMCK_01633 4.06e-62 - - - L ko:K07497 - ko00000 hmm pf00665
NNFDHMCK_01634 4.69e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NNFDHMCK_01635 8.24e-99 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NNFDHMCK_01636 1.78e-34 - - - - - - - -
NNFDHMCK_01637 3.88e-160 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNFDHMCK_01638 4.21e-129 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NNFDHMCK_01639 8.74e-104 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNFDHMCK_01640 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NNFDHMCK_01641 4.14e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNFDHMCK_01642 2.56e-32 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NNFDHMCK_01643 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNFDHMCK_01644 3.13e-73 - - - S - - - Protein of unknown function (DUF1129)
NNFDHMCK_01645 8.51e-115 - - - S - - - Bacterial membrane protein, YfhO
NNFDHMCK_01646 1.82e-67 - - - I - - - Alpha/beta hydrolase family
NNFDHMCK_01647 8.88e-14 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NNFDHMCK_01648 2.75e-46 - - - - - - - -
NNFDHMCK_01649 3.91e-287 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNFDHMCK_01650 2.18e-181 - - - V - - - Pfam:Methyltransf_26
NNFDHMCK_01653 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNFDHMCK_01654 8.64e-24 - - - - - - - -
NNFDHMCK_01655 9.07e-91 - - - - - - - -
NNFDHMCK_01656 3.17e-13 - - - L - - - recombinase activity
NNFDHMCK_01657 7.41e-17 - - - - - - - -
NNFDHMCK_01658 2.24e-23 - - - L - - - nuclease
NNFDHMCK_01659 5.12e-36 - - - S - - - Short C-terminal domain
NNFDHMCK_01662 7.58e-31 - - - K - - - Helix-turn-helix domain
NNFDHMCK_01663 3.82e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
NNFDHMCK_01664 1.74e-180 - - - K - - - Transcriptional regulator
NNFDHMCK_01670 9.24e-68 - - - S - - - Putative HNHc nuclease
NNFDHMCK_01684 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NNFDHMCK_01685 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNFDHMCK_01686 1.24e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NNFDHMCK_01687 9.78e-82 - - - C - - - FMN binding
NNFDHMCK_01688 2.37e-290 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNFDHMCK_01690 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNFDHMCK_01691 3.46e-78 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NNFDHMCK_01692 3.84e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NNFDHMCK_01693 3.14e-104 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NNFDHMCK_01694 1.97e-126 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNFDHMCK_01695 6.41e-167 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
NNFDHMCK_01696 7e-94 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNFDHMCK_01697 1.03e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NNFDHMCK_01698 1.48e-202 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NNFDHMCK_01699 2.26e-70 oxyR5 - - K - - - Transcriptional regulator
NNFDHMCK_01700 5.06e-242 - - - C - - - FMN_bind
NNFDHMCK_01701 7.24e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NNFDHMCK_01703 1.64e-232 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NNFDHMCK_01704 5.9e-178 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNFDHMCK_01705 1.66e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNFDHMCK_01706 3.78e-84 - - - G - - - PTS system sorbose subfamily IIB component
NNFDHMCK_01707 7.67e-139 - - - G - - - PTS system sorbose-specific iic component
NNFDHMCK_01708 1.68e-157 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NNFDHMCK_01709 1.82e-175 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NNFDHMCK_01711 1.05e-61 - - - M - - - LysM domain protein
NNFDHMCK_01712 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNFDHMCK_01713 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NNFDHMCK_01714 4.84e-40 - - - K - - - transcriptional regulator (TetR family)
NNFDHMCK_01715 7.13e-137 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NNFDHMCK_01716 3.65e-110 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01717 3.37e-84 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNFDHMCK_01718 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNFDHMCK_01719 4e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NNFDHMCK_01720 1.97e-283 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNFDHMCK_01721 7.24e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNFDHMCK_01722 8.95e-73 yjcF - - J - - - HAD-hyrolase-like
NNFDHMCK_01723 4.31e-49 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNFDHMCK_01724 3.96e-163 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNFDHMCK_01725 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNFDHMCK_01726 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NNFDHMCK_01727 2.6e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNFDHMCK_01728 7.36e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNFDHMCK_01729 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNFDHMCK_01730 7.08e-113 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNFDHMCK_01731 1.83e-172 - - - K - - - Transcriptional regulator
NNFDHMCK_01732 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NNFDHMCK_01733 2.37e-145 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NNFDHMCK_01734 1.06e-28 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NNFDHMCK_01736 2.96e-47 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NNFDHMCK_01737 6.75e-81 - - - H - - - Methyltransferase domain
NNFDHMCK_01739 3.5e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNFDHMCK_01740 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NNFDHMCK_01741 9.3e-211 yclK - - T - - - Histidine kinase
NNFDHMCK_01742 2.09e-295 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NNFDHMCK_01743 1.91e-306 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNFDHMCK_01744 5.54e-139 dkgB - - S - - - reductase
NNFDHMCK_01745 1.82e-33 - - - - - - - -
NNFDHMCK_01746 6.86e-100 - - - F - - - Phosphorylase superfamily
NNFDHMCK_01747 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NNFDHMCK_01748 3.47e-79 ytkL - - S - - - Beta-lactamase superfamily domain
NNFDHMCK_01749 2.86e-123 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNFDHMCK_01750 4.53e-156 yibE - - S - - - overlaps another CDS with the same product name
NNFDHMCK_01751 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
NNFDHMCK_01752 1.29e-11 - - - - - - - -
NNFDHMCK_01753 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNFDHMCK_01754 7.59e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01755 6.28e-44 - - - K - - - Bacterial regulatory proteins, tetR family
NNFDHMCK_01756 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNFDHMCK_01757 1.1e-277 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNFDHMCK_01758 2.38e-189 - - - G - - - Transporter, major facilitator family protein
NNFDHMCK_01759 5.54e-111 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNFDHMCK_01760 5.29e-191 hpk31 - - T - - - Histidine kinase
NNFDHMCK_01761 1.21e-145 vanR - - K - - - response regulator
NNFDHMCK_01762 7.86e-106 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNFDHMCK_01763 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNFDHMCK_01765 1.65e-09 - - - S - - - sequence-specific DNA binding
NNFDHMCK_01766 0.000539 - - - K - - - Transcriptional
NNFDHMCK_01767 4.57e-127 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)