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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GNFOHPPO_00001	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GNFOHPPO_00002	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
GNFOHPPO_00003	1.51e-196	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
GNFOHPPO_00004	5.87e-313	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
GNFOHPPO_00005	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
GNFOHPPO_00006	3.72e-235	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
GNFOHPPO_00007	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
GNFOHPPO_00008	1.25e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
GNFOHPPO_00009	2e-210	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFOHPPO_00010	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GNFOHPPO_00011	3.68e-50	ykoA	-	-	-	-	-	-	-
GNFOHPPO_00012	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GNFOHPPO_00013	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GNFOHPPO_00014	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
GNFOHPPO_00015	6.81e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_00016	3.11e-271	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
GNFOHPPO_00017	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_00018	2e-246	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GNFOHPPO_00019	1.48e-136	yknW	-	-	S	-	-	-	Yip1 domain
GNFOHPPO_00020	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GNFOHPPO_00021	2.92e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
GNFOHPPO_00022	2.64e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
GNFOHPPO_00023	1.61e-308	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
GNFOHPPO_00024	1.71e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GNFOHPPO_00025	1.93e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GNFOHPPO_00026	3.59e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
GNFOHPPO_00027	3.04e-126	rok	-	-	K	-	-	-	Repressor of ComK
GNFOHPPO_00028	1.35e-102	ykuV	-	-	CO	-	-	-	thiol-disulfide
GNFOHPPO_00029	1.48e-179	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
GNFOHPPO_00030	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
GNFOHPPO_00031	6.57e-275	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GNFOHPPO_00032	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GNFOHPPO_00033	7.53e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GNFOHPPO_00034	1.87e-217	ykuO	-	-	-	-	-	-	-
GNFOHPPO_00035	2.59e-116	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GNFOHPPO_00036	2.65e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00037	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
GNFOHPPO_00038	4.54e-37	ykzF	-	-	S	-	-	-	Antirepressor AbbA
GNFOHPPO_00039	8.79e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
GNFOHPPO_00040	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00041	7.72e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
GNFOHPPO_00043	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_00044	5.66e-201	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
GNFOHPPO_00045	8.88e-117	ykuD	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00046	6.53e-308	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_00047	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
GNFOHPPO_00048	4.75e-214	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
GNFOHPPO_00049	7.46e-14	-	-	-	-	-	-	-	-
GNFOHPPO_00050	1.62e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFOHPPO_00051	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_00052	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GNFOHPPO_00053	2.66e-158	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
GNFOHPPO_00054	2.83e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GNFOHPPO_00055	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
GNFOHPPO_00056	6.84e-254	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
GNFOHPPO_00057	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_00058	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GNFOHPPO_00059	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
GNFOHPPO_00060	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_00061	4.61e-198	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
GNFOHPPO_00062	2.89e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00064	9.91e-265	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
GNFOHPPO_00065	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
GNFOHPPO_00066	2.1e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
GNFOHPPO_00067	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_00068	1.77e-143	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
GNFOHPPO_00069	4.16e-38	-	-	-	-	-	-	-	-
GNFOHPPO_00070	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00071	1.47e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
GNFOHPPO_00073	7.12e-204	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
GNFOHPPO_00074	1.26e-46	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
GNFOHPPO_00075	1.67e-269	-	-	-	M	-	-	-	Glycosyl transferases group 1
GNFOHPPO_00076	2.38e-43	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GNFOHPPO_00077	5.19e-170	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_00078	8.33e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
GNFOHPPO_00079	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GNFOHPPO_00080	1.76e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GNFOHPPO_00081	8.23e-106	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
GNFOHPPO_00082	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GNFOHPPO_00083	9.75e-256	-	-	-	-	-	-	-	-
GNFOHPPO_00084	6.6e-233	ykvI	-	-	S	-	-	-	membrane
GNFOHPPO_00085	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GNFOHPPO_00086	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
GNFOHPPO_00087	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
GNFOHPPO_00088	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
GNFOHPPO_00089	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
GNFOHPPO_00091	1.5e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GNFOHPPO_00092	2.33e-149	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GNFOHPPO_00093	1.4e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GNFOHPPO_00094	2.73e-289	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GNFOHPPO_00095	7.34e-291	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFOHPPO_00096	4.7e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GNFOHPPO_00097	9.94e-287	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GNFOHPPO_00098	3.65e-250	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GNFOHPPO_00100	4.58e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GNFOHPPO_00101	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_00102	2.35e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
GNFOHPPO_00103	1.41e-30	ykzE	-	-	-	-	-	-	-
GNFOHPPO_00104	4.97e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
GNFOHPPO_00105	4.63e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
GNFOHPPO_00106	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GNFOHPPO_00107	1.97e-162	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
GNFOHPPO_00108	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
GNFOHPPO_00109	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
GNFOHPPO_00110	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_00111	3.54e-174	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GNFOHPPO_00112	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
GNFOHPPO_00113	4e-201	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GNFOHPPO_00114	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
GNFOHPPO_00115	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
GNFOHPPO_00116	1.98e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
GNFOHPPO_00117	5.25e-37	ykoL	-	-	-	-	-	-	-
GNFOHPPO_00118	1.11e-23	-	-	-	-	-	-	-	-
GNFOHPPO_00119	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
GNFOHPPO_00120	8.66e-310	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
GNFOHPPO_00122	3.79e-311	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
GNFOHPPO_00123	9.8e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
GNFOHPPO_00124	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_00125	1.87e-170	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GNFOHPPO_00126	1.89e-191	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GNFOHPPO_00127	2.12e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
GNFOHPPO_00128	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GNFOHPPO_00129	9.09e-155	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GNFOHPPO_00130	9.37e-276	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_00131	1.74e-181	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
GNFOHPPO_00132	1.43e-274	-	-	-	M	-	-	-	Glycosyl transferase family 2
GNFOHPPO_00134	1.39e-76	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GNFOHPPO_00135	1.92e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
GNFOHPPO_00136	1.2e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
GNFOHPPO_00137	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
GNFOHPPO_00138	1.37e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GNFOHPPO_00139	1.19e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GNFOHPPO_00140	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GNFOHPPO_00141	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
GNFOHPPO_00142	5.81e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
GNFOHPPO_00143	5.44e-132	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GNFOHPPO_00144	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
GNFOHPPO_00145	3.59e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
GNFOHPPO_00146	2.07e-263	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
GNFOHPPO_00147	3.28e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00148	4.6e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GNFOHPPO_00149	2.32e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
GNFOHPPO_00150	8.34e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
GNFOHPPO_00151	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GNFOHPPO_00152	3.21e-243	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00153	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00154	2.4e-205	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00155	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
GNFOHPPO_00157	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
GNFOHPPO_00158	5.3e-276	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNFOHPPO_00160	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
GNFOHPPO_00161	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GNFOHPPO_00162	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
GNFOHPPO_00163	2.3e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
GNFOHPPO_00164	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
GNFOHPPO_00165	1.43e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
GNFOHPPO_00166	3.81e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
GNFOHPPO_00167	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
GNFOHPPO_00168	1.73e-215	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
GNFOHPPO_00169	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
GNFOHPPO_00170	6.44e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
GNFOHPPO_00171	1.82e-177	xepA	-	-	-	-	-	-	-
GNFOHPPO_00172	9.32e-40	xkdX	-	-	-	-	-	-	-
GNFOHPPO_00174	6.2e-110	-	-	-	-	-	-	-	-
GNFOHPPO_00175	3.63e-37	-	-	-	-	-	-	-	-
GNFOHPPO_00176	7.1e-113	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
GNFOHPPO_00177	7.24e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GNFOHPPO_00178	5.77e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
GNFOHPPO_00179	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
GNFOHPPO_00180	1.08e-205	xkdQ	-	-	G	-	-	-	NLP P60 protein
GNFOHPPO_00181	8.94e-143	xkdP	-	-	S	-	-	-	Lysin motif
GNFOHPPO_00182	1.78e-279	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
GNFOHPPO_00183	4.33e-27	-	-	-	-	-	-	-	-
GNFOHPPO_00184	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
GNFOHPPO_00185	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
GNFOHPPO_00186	6.61e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
GNFOHPPO_00187	1.45e-20	-	-	-	-	-	-	-	-
GNFOHPPO_00188	1.05e-74	xkdJ	-	-	-	-	-	-	-
GNFOHPPO_00189	1.46e-78	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
GNFOHPPO_00190	6.74e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
GNFOHPPO_00191	5.11e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
GNFOHPPO_00192	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
GNFOHPPO_00193	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
GNFOHPPO_00194	6.78e-304	xkdE3	-	-	S	-	-	-	portal protein
GNFOHPPO_00195	2.36e-263	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
GNFOHPPO_00196	9.67e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
GNFOHPPO_00197	3.05e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GNFOHPPO_00201	5.08e-195	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
GNFOHPPO_00203	3.78e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFOHPPO_00204	1.32e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
GNFOHPPO_00206	1.31e-142	yjqB	-	-	S	-	-	-	phage-related replication protein
GNFOHPPO_00207	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
GNFOHPPO_00208	8.26e-222	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
GNFOHPPO_00210	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
GNFOHPPO_00211	4.15e-103	yjoA	-	-	S	-	-	-	DinB family
GNFOHPPO_00212	1.86e-166	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GNFOHPPO_00213	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
GNFOHPPO_00214	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
GNFOHPPO_00215	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
GNFOHPPO_00216	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
GNFOHPPO_00217	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
GNFOHPPO_00218	7.49e-281	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GNFOHPPO_00219	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
GNFOHPPO_00220	3.63e-120	yjlB	-	-	S	-	-	-	Cupin domain
GNFOHPPO_00221	1.18e-226	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
GNFOHPPO_00222	9.22e-168	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00223	4.15e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
GNFOHPPO_00224	7.93e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
GNFOHPPO_00225	1.73e-40	-	-	-	-	-	-	-	-
GNFOHPPO_00226	1.46e-284	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GNFOHPPO_00227	4.43e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
GNFOHPPO_00228	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
GNFOHPPO_00229	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
GNFOHPPO_00230	5.57e-129	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
GNFOHPPO_00231	1.04e-90	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
GNFOHPPO_00232	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
GNFOHPPO_00234	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
GNFOHPPO_00235	3.41e-68	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_00236	6.86e-46	-	-	-	-	-	-	-	-
GNFOHPPO_00237	1.02e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GNFOHPPO_00238	2.4e-178	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
GNFOHPPO_00239	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GNFOHPPO_00240	6.04e-65	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_00241	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GNFOHPPO_00242	1.9e-277	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GNFOHPPO_00243	3.61e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GNFOHPPO_00244	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GNFOHPPO_00245	2.48e-277	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
GNFOHPPO_00246	1.06e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_00247	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
GNFOHPPO_00248	4.44e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
GNFOHPPO_00249	4.04e-211	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
GNFOHPPO_00250	1.84e-40	-	-	-	E	-	-	-	Glyoxalase-like domain
GNFOHPPO_00251	1.5e-24	-	-	-	E	-	-	-	Glyoxalase-like domain
GNFOHPPO_00253	0.0	-	-	-	S	-	-	-	Bacterial EndoU nuclease
GNFOHPPO_00254	7.07e-30	-	-	-	-	-	-	-	-
GNFOHPPO_00255	3.97e-109	-	-	-	-	-	-	-	-
GNFOHPPO_00256	3.98e-42	-	-	-	-	-	-	-	-
GNFOHPPO_00258	8.08e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GNFOHPPO_00259	1.13e-270	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GNFOHPPO_00260	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
GNFOHPPO_00261	5.73e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
GNFOHPPO_00262	3.66e-98	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFOHPPO_00264	4.32e-48	-	-	-	K	-	-	-	SpoVT / AbrB like domain
GNFOHPPO_00265	2.48e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GNFOHPPO_00266	1.6e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
GNFOHPPO_00267	4.35e-140	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
GNFOHPPO_00268	1.44e-47	-	-	-	-	-	-	-	-
GNFOHPPO_00269	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GNFOHPPO_00270	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
GNFOHPPO_00271	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
GNFOHPPO_00274	3.41e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
GNFOHPPO_00275	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
GNFOHPPO_00276	8.38e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
GNFOHPPO_00277	7.48e-100	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
GNFOHPPO_00278	1.61e-116	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
GNFOHPPO_00279	1.12e-103	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
GNFOHPPO_00280	1.95e-124	yjbX	-	-	S	-	-	-	Spore coat protein
GNFOHPPO_00281	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
GNFOHPPO_00282	1.5e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GNFOHPPO_00283	8.18e-243	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GNFOHPPO_00284	1.48e-172	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GNFOHPPO_00285	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
GNFOHPPO_00286	1.31e-267	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
GNFOHPPO_00287	2.71e-137	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
GNFOHPPO_00288	4.88e-178	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GNFOHPPO_00289	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GNFOHPPO_00290	5.27e-184	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GNFOHPPO_00291	1.12e-209	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GNFOHPPO_00292	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GNFOHPPO_00293	1.56e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
GNFOHPPO_00294	2.03e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
GNFOHPPO_00295	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00296	7.66e-153	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GNFOHPPO_00297	1.22e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
GNFOHPPO_00298	6.05e-220	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
GNFOHPPO_00299	3.14e-27	-	-	-	-	-	-	-	-
GNFOHPPO_00300	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
GNFOHPPO_00301	4.01e-282	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GNFOHPPO_00302	1.97e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GNFOHPPO_00303	3.93e-141	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
GNFOHPPO_00304	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GNFOHPPO_00305	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFOHPPO_00306	2.03e-294	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
GNFOHPPO_00307	2.19e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00308	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00309	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00310	2.53e-213	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00311	1.03e-66	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GNFOHPPO_00312	2.2e-283	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GNFOHPPO_00313	1.45e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
GNFOHPPO_00314	1.52e-188	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
GNFOHPPO_00315	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00316	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_00317	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
GNFOHPPO_00318	8.8e-239	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00319	6.88e-231	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_00320	7.48e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
GNFOHPPO_00321	1.83e-298	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GNFOHPPO_00322	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GNFOHPPO_00323	2.82e-44	yjzB	-	-	-	-	-	-	-
GNFOHPPO_00324	1.3e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
GNFOHPPO_00325	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
GNFOHPPO_00326	2.12e-137	yjaV	-	-	-	-	-	-	-
GNFOHPPO_00327	4.68e-180	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
GNFOHPPO_00328	5.24e-33	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GNFOHPPO_00329	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
GNFOHPPO_00330	2.48e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GNFOHPPO_00331	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
GNFOHPPO_00332	2.41e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GNFOHPPO_00333	4.84e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
GNFOHPPO_00334	7.67e-177	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
GNFOHPPO_00335	5.39e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GNFOHPPO_00336	1.75e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GNFOHPPO_00337	1.96e-120	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
GNFOHPPO_00338	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
GNFOHPPO_00339	1.37e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GNFOHPPO_00340	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
GNFOHPPO_00341	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
GNFOHPPO_00342	1.52e-198	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
GNFOHPPO_00343	1.49e-11	-	-	-	-	-	-	-	-
GNFOHPPO_00344	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
GNFOHPPO_00345	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
GNFOHPPO_00346	1.61e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_00347	1.3e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00349	3.61e-307	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
GNFOHPPO_00350	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
GNFOHPPO_00351	1.08e-221	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
GNFOHPPO_00352	1.85e-205	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
GNFOHPPO_00353	6.39e-79	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
GNFOHPPO_00354	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GNFOHPPO_00355	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_00356	2.27e-103	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
GNFOHPPO_00357	4.42e-116	yisT	-	-	S	-	-	-	DinB family
GNFOHPPO_00358	1.35e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00359	6.12e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
GNFOHPPO_00360	9.75e-174	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
GNFOHPPO_00361	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GNFOHPPO_00362	9.2e-125	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
GNFOHPPO_00363	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
GNFOHPPO_00364	8.91e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GNFOHPPO_00365	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
GNFOHPPO_00366	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
GNFOHPPO_00367	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
GNFOHPPO_00368	3.46e-108	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
GNFOHPPO_00369	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
GNFOHPPO_00370	1.61e-84	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
GNFOHPPO_00371	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
GNFOHPPO_00372	1.53e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
GNFOHPPO_00373	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
GNFOHPPO_00374	2e-284	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GNFOHPPO_00375	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GNFOHPPO_00376	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
GNFOHPPO_00377	1.07e-127	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
GNFOHPPO_00378	4.92e-120	yhjR	-	-	S	-	-	-	Rubrerythrin
GNFOHPPO_00379	1.11e-141	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
GNFOHPPO_00380	4.57e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_00381	2.82e-261	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
GNFOHPPO_00382	5.63e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_00383	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
GNFOHPPO_00384	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GNFOHPPO_00385	1.64e-144	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_00386	2.39e-78	yhjD	-	-	-	-	-	-	-
GNFOHPPO_00387	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
GNFOHPPO_00388	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GNFOHPPO_00389	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
GNFOHPPO_00390	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
GNFOHPPO_00391	6.58e-165	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
GNFOHPPO_00392	5.77e-210	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
GNFOHPPO_00393	7.57e-86	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
GNFOHPPO_00394	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
GNFOHPPO_00395	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
GNFOHPPO_00396	1.35e-42	yhzC	-	-	S	-	-	-	IDEAL
GNFOHPPO_00397	1.35e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_00398	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
GNFOHPPO_00399	1.13e-276	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
GNFOHPPO_00400	6.21e-115	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
GNFOHPPO_00401	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
GNFOHPPO_00402	1.82e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GNFOHPPO_00403	7.04e-133	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
GNFOHPPO_00404	7.99e-196	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GNFOHPPO_00405	3.46e-265	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
GNFOHPPO_00406	1.11e-301	yhfN	-	-	O	-	-	-	Peptidase M48
GNFOHPPO_00407	2.38e-86	yhfM	-	-	-	-	-	-	-
GNFOHPPO_00408	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
GNFOHPPO_00409	1.09e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
GNFOHPPO_00410	1.52e-240	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
GNFOHPPO_00411	5.69e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GNFOHPPO_00413	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GNFOHPPO_00414	1.27e-251	yhfE	-	-	G	-	-	-	peptidase M42
GNFOHPPO_00416	4.87e-234	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GNFOHPPO_00417	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
GNFOHPPO_00418	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_00419	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GNFOHPPO_00420	4.49e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GNFOHPPO_00421	1.27e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GNFOHPPO_00422	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GNFOHPPO_00423	7.3e-116	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
GNFOHPPO_00424	1.33e-309	yhfA	-	-	C	-	-	-	membrane
GNFOHPPO_00425	1.86e-287	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GNFOHPPO_00426	1.01e-160	ecsC	-	-	S	-	-	-	EcsC protein family
GNFOHPPO_00427	2.24e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GNFOHPPO_00428	1.5e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
GNFOHPPO_00429	1.37e-103	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GNFOHPPO_00430	1.69e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GNFOHPPO_00431	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
GNFOHPPO_00432	2.55e-24	-	-	-	-	-	-	-	-
GNFOHPPO_00433	4.74e-55	yhaH	-	-	S	-	-	-	YtxH-like protein
GNFOHPPO_00434	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
GNFOHPPO_00435	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
GNFOHPPO_00436	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
GNFOHPPO_00437	6.5e-186	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GNFOHPPO_00438	3.48e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
GNFOHPPO_00439	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
GNFOHPPO_00440	0.0	yhaN	-	-	L	-	-	-	AAA domain
GNFOHPPO_00441	1.29e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
GNFOHPPO_00442	4.14e-278	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
GNFOHPPO_00443	3.92e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_00444	7.01e-20	-	-	-	S	-	-	-	YhzD-like protein
GNFOHPPO_00445	4.11e-175	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
GNFOHPPO_00447	4.58e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
GNFOHPPO_00448	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
GNFOHPPO_00449	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
GNFOHPPO_00450	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
GNFOHPPO_00451	8.46e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GNFOHPPO_00452	6.08e-259	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
GNFOHPPO_00453	8.1e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GNFOHPPO_00454	1.36e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
GNFOHPPO_00455	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
GNFOHPPO_00456	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
GNFOHPPO_00457	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
GNFOHPPO_00458	9.47e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
GNFOHPPO_00460	8.12e-144	yheG	-	-	GM	-	-	-	NAD(P)H-binding
GNFOHPPO_00461	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
GNFOHPPO_00462	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
GNFOHPPO_00464	2.49e-110	-	-	-	T	-	-	-	universal stress protein
GNFOHPPO_00465	2.29e-125	ymcC	-	-	S	-	-	-	Membrane
GNFOHPPO_00466	1.22e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00467	2.41e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GNFOHPPO_00468	4.89e-201	nodB1	-	-	G	-	-	-	deacetylase
GNFOHPPO_00469	7.18e-181	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GNFOHPPO_00470	6.68e-262	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
GNFOHPPO_00471	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
GNFOHPPO_00472	1.28e-165	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GNFOHPPO_00473	9.68e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GNFOHPPO_00474	1.01e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GNFOHPPO_00475	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
GNFOHPPO_00476	3.31e-302	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GNFOHPPO_00477	4.22e-288	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
GNFOHPPO_00478	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
GNFOHPPO_00479	3.94e-307	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
GNFOHPPO_00480	3.75e-141	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GNFOHPPO_00481	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_00482	9.78e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
GNFOHPPO_00483	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
GNFOHPPO_00484	1.78e-268	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GNFOHPPO_00485	1.69e-315	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
GNFOHPPO_00486	5.51e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_00487	4.9e-263	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
GNFOHPPO_00488	7e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_00489	6.44e-177	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
GNFOHPPO_00490	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
GNFOHPPO_00491	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
GNFOHPPO_00492	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
GNFOHPPO_00493	3.25e-97	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
GNFOHPPO_00494	4.93e-296	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
GNFOHPPO_00495	4.18e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
GNFOHPPO_00496	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
GNFOHPPO_00497	1.14e-114	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
GNFOHPPO_00498	3.15e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_00499	1.45e-260	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_00500	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
GNFOHPPO_00501	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GNFOHPPO_00502	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GNFOHPPO_00503	1.34e-197	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GNFOHPPO_00504	1.04e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GNFOHPPO_00505	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GNFOHPPO_00506	8.3e-203	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
GNFOHPPO_00507	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GNFOHPPO_00508	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
GNFOHPPO_00509	4.66e-296	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
GNFOHPPO_00510	4.48e-189	yqfA	-	-	S	-	-	-	UPF0365 protein
GNFOHPPO_00511	1.26e-85	yqfB	-	-	-	-	-	-	-
GNFOHPPO_00512	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
GNFOHPPO_00513	8.17e-286	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
GNFOHPPO_00514	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
GNFOHPPO_00515	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
GNFOHPPO_00516	7.14e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GNFOHPPO_00517	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
GNFOHPPO_00518	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GNFOHPPO_00519	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GNFOHPPO_00520	6e-24	-	-	-	S	-	-	-	YqzL-like protein
GNFOHPPO_00521	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GNFOHPPO_00522	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GNFOHPPO_00523	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GNFOHPPO_00524	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
GNFOHPPO_00525	5.46e-192	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GNFOHPPO_00526	1.36e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
GNFOHPPO_00527	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GNFOHPPO_00528	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GNFOHPPO_00529	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
GNFOHPPO_00530	8.52e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GNFOHPPO_00531	7.6e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GNFOHPPO_00532	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GNFOHPPO_00533	3.02e-84	yqfQ	-	-	S	-	-	-	YqfQ-like protein
GNFOHPPO_00534	1.05e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GNFOHPPO_00535	4.23e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GNFOHPPO_00536	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
GNFOHPPO_00537	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_00538	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
GNFOHPPO_00539	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
GNFOHPPO_00540	3.34e-80	yqfX	-	-	S	-	-	-	membrane
GNFOHPPO_00541	8.02e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GNFOHPPO_00542	1.84e-64	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
GNFOHPPO_00543	6.98e-164	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
GNFOHPPO_00544	2.76e-99	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
GNFOHPPO_00545	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
GNFOHPPO_00546	6.78e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
GNFOHPPO_00547	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
GNFOHPPO_00548	9.1e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GNFOHPPO_00549	6.1e-204	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GNFOHPPO_00550	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
GNFOHPPO_00551	4.13e-186	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GNFOHPPO_00552	2.32e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GNFOHPPO_00553	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GNFOHPPO_00554	3.42e-68	yqzD	-	-	-	-	-	-	-
GNFOHPPO_00555	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GNFOHPPO_00556	1.74e-125	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GNFOHPPO_00557	5.38e-11	yqgO	-	-	-	-	-	-	-
GNFOHPPO_00558	1.71e-274	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
GNFOHPPO_00559	9.1e-39	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
GNFOHPPO_00560	5.87e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
GNFOHPPO_00561	2.06e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
GNFOHPPO_00562	3.12e-255	yqgU	-	-	-	-	-	-	-
GNFOHPPO_00563	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
GNFOHPPO_00564	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
GNFOHPPO_00565	5.96e-158	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
GNFOHPPO_00566	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
GNFOHPPO_00567	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
GNFOHPPO_00569	2.49e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GNFOHPPO_00570	1.78e-302	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
GNFOHPPO_00571	6.43e-239	yqxL	-	-	P	-	-	-	Mg2 transporter protein
GNFOHPPO_00572	1.34e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GNFOHPPO_00573	2.93e-236	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
GNFOHPPO_00574	4.46e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
GNFOHPPO_00575	9.65e-95	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
GNFOHPPO_00576	1.27e-25	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
GNFOHPPO_00577	1.64e-81	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
GNFOHPPO_00578	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
GNFOHPPO_00579	1.39e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
GNFOHPPO_00580	1.98e-157	yqxM	-	-	-	ko:K19433	-	ko00000	-
GNFOHPPO_00581	1.89e-102	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
GNFOHPPO_00582	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
GNFOHPPO_00583	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
GNFOHPPO_00584	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
GNFOHPPO_00585	3.06e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
GNFOHPPO_00586	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
GNFOHPPO_00587	9.52e-264	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
GNFOHPPO_00588	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GNFOHPPO_00589	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GNFOHPPO_00590	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
GNFOHPPO_00591	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GNFOHPPO_00592	1.62e-96	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GNFOHPPO_00593	8.17e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
GNFOHPPO_00594	7.65e-83	yqhP	-	-	-	-	-	-	-
GNFOHPPO_00595	2.45e-219	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
GNFOHPPO_00596	3.99e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
GNFOHPPO_00597	6.04e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
GNFOHPPO_00598	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GNFOHPPO_00599	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
GNFOHPPO_00600	3.12e-221	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
GNFOHPPO_00601	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
GNFOHPPO_00602	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
GNFOHPPO_00603	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
GNFOHPPO_00604	5.23e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
GNFOHPPO_00605	1.05e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
GNFOHPPO_00606	3.48e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
GNFOHPPO_00607	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
GNFOHPPO_00608	2.32e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GNFOHPPO_00609	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GNFOHPPO_00610	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00611	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GNFOHPPO_00612	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GNFOHPPO_00613	7.95e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GNFOHPPO_00614	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GNFOHPPO_00615	3.31e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GNFOHPPO_00616	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GNFOHPPO_00617	4.16e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
GNFOHPPO_00618	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GNFOHPPO_00619	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GNFOHPPO_00620	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
GNFOHPPO_00621	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GNFOHPPO_00622	1.68e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GNFOHPPO_00625	9.67e-274	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GNFOHPPO_00627	6.93e-147	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
GNFOHPPO_00628	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
GNFOHPPO_00630	2.3e-135	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
GNFOHPPO_00631	1.1e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GNFOHPPO_00632	5.6e-272	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GNFOHPPO_00633	1.45e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
GNFOHPPO_00634	9.14e-263	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
GNFOHPPO_00635	4.36e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
GNFOHPPO_00636	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
GNFOHPPO_00637	1.15e-204	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GNFOHPPO_00638	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
GNFOHPPO_00639	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
GNFOHPPO_00640	9.24e-193	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
GNFOHPPO_00641	1.58e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
GNFOHPPO_00642	1.2e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
GNFOHPPO_00643	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GNFOHPPO_00644	2.75e-222	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GNFOHPPO_00645	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GNFOHPPO_00646	1.86e-286	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GNFOHPPO_00647	6.05e-219	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GNFOHPPO_00648	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
GNFOHPPO_00649	5.83e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
GNFOHPPO_00650	4.25e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
GNFOHPPO_00651	1.05e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
GNFOHPPO_00652	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
GNFOHPPO_00653	9.08e-124	yqjB	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00655	4.64e-96	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
GNFOHPPO_00656	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GNFOHPPO_00657	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
GNFOHPPO_00658	2.91e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GNFOHPPO_00659	1.3e-34	yqzJ	-	-	-	-	-	-	-
GNFOHPPO_00660	4.71e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GNFOHPPO_00661	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GNFOHPPO_00662	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GNFOHPPO_00663	5.59e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GNFOHPPO_00664	2.72e-190	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GNFOHPPO_00665	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GNFOHPPO_00666	3.19e-66	-	-	-	S	-	-	-	GlpM protein
GNFOHPPO_00667	1.53e-209	-	-	-	K	-	-	-	LysR substrate binding domain
GNFOHPPO_00668	5.26e-123	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GNFOHPPO_00669	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_00672	9.17e-313	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GNFOHPPO_00673	7.97e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GNFOHPPO_00674	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00675	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00676	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00677	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00678	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00679	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_00680	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GNFOHPPO_00681	2.32e-280	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
GNFOHPPO_00682	7.87e-306	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
GNFOHPPO_00683	9.75e-175	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
GNFOHPPO_00684	8.27e-187	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNFOHPPO_00685	3.78e-221	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
GNFOHPPO_00686	1.68e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_00687	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
GNFOHPPO_00688	6.33e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GNFOHPPO_00689	2.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFOHPPO_00691	5.29e-242	yueF	-	-	S	-	-	-	transporter activity
GNFOHPPO_00693	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
GNFOHPPO_00694	2.7e-298	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GNFOHPPO_00695	1.15e-114	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
GNFOHPPO_00696	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
GNFOHPPO_00697	3.53e-227	yqkA	-	-	K	-	-	-	GrpB protein
GNFOHPPO_00698	4.44e-79	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
GNFOHPPO_00699	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
GNFOHPPO_00700	1.42e-226	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
GNFOHPPO_00701	6.8e-10	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
GNFOHPPO_00702	3.77e-217	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
GNFOHPPO_00703	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
GNFOHPPO_00704	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
GNFOHPPO_00705	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
GNFOHPPO_00706	1.15e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00707	5.31e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
GNFOHPPO_00708	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
GNFOHPPO_00709	3.56e-313	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
GNFOHPPO_00710	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
GNFOHPPO_00711	1.96e-30	-	-	-	-	-	-	-	-
GNFOHPPO_00712	1.72e-44	yqkK	-	-	-	-	-	-	-
GNFOHPPO_00714	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GNFOHPPO_00715	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
GNFOHPPO_00716	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
GNFOHPPO_00717	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
GNFOHPPO_00718	1.22e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GNFOHPPO_00719	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GNFOHPPO_00720	3.52e-273	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GNFOHPPO_00721	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
GNFOHPPO_00722	1.95e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GNFOHPPO_00723	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_00724	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
GNFOHPPO_00725	1.43e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
GNFOHPPO_00726	9.92e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
GNFOHPPO_00727	4.74e-243	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
GNFOHPPO_00728	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
GNFOHPPO_00729	1.31e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
GNFOHPPO_00730	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
GNFOHPPO_00731	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GNFOHPPO_00732	5.64e-200	ypuA	-	-	S	-	-	-	Secreted protein
GNFOHPPO_00733	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNFOHPPO_00734	6.76e-106	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
GNFOHPPO_00735	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GNFOHPPO_00736	4.92e-71	ypuD	-	-	-	-	-	-	-
GNFOHPPO_00737	2.27e-269	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GNFOHPPO_00738	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
GNFOHPPO_00739	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GNFOHPPO_00740	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GNFOHPPO_00741	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFOHPPO_00742	5.71e-121	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
GNFOHPPO_00744	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GNFOHPPO_00745	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GNFOHPPO_00746	1.51e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
GNFOHPPO_00747	6.31e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GNFOHPPO_00748	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
GNFOHPPO_00749	2.58e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
GNFOHPPO_00750	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GNFOHPPO_00751	3.55e-127	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GNFOHPPO_00752	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
GNFOHPPO_00753	4.39e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GNFOHPPO_00754	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_00755	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_00756	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_00757	6.56e-253	rsiX	-	-	-	-	-	-	-
GNFOHPPO_00758	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFOHPPO_00759	1.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GNFOHPPO_00760	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
GNFOHPPO_00761	2.69e-256	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
GNFOHPPO_00762	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
GNFOHPPO_00763	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
GNFOHPPO_00764	1.07e-134	ypbE	-	-	M	-	-	-	Lysin motif
GNFOHPPO_00765	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
GNFOHPPO_00766	5.46e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
GNFOHPPO_00767	1.36e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GNFOHPPO_00768	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
GNFOHPPO_00769	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
GNFOHPPO_00770	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
GNFOHPPO_00771	3.77e-213	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
GNFOHPPO_00772	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
GNFOHPPO_00773	7.01e-74	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
GNFOHPPO_00774	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
GNFOHPPO_00775	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GNFOHPPO_00776	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GNFOHPPO_00777	5.67e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GNFOHPPO_00778	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
GNFOHPPO_00779	6.19e-136	yphA	-	-	-	-	-	-	-
GNFOHPPO_00780	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GNFOHPPO_00781	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GNFOHPPO_00782	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
GNFOHPPO_00783	6.87e-173	yphF	-	-	-	-	-	-	-
GNFOHPPO_00784	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GNFOHPPO_00785	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GNFOHPPO_00786	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
GNFOHPPO_00787	2.09e-45	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GNFOHPPO_00788	2.29e-176	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GNFOHPPO_00789	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GNFOHPPO_00790	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GNFOHPPO_00791	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GNFOHPPO_00792	5.74e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
GNFOHPPO_00793	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GNFOHPPO_00794	7.79e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GNFOHPPO_00795	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GNFOHPPO_00796	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GNFOHPPO_00797	5.82e-212	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GNFOHPPO_00798	7.06e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
GNFOHPPO_00799	1.83e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
GNFOHPPO_00800	1.73e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GNFOHPPO_00801	2.8e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GNFOHPPO_00802	9.08e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GNFOHPPO_00803	1.24e-260	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
GNFOHPPO_00804	6.98e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GNFOHPPO_00805	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
GNFOHPPO_00806	1.06e-128	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
GNFOHPPO_00807	5.77e-102	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
GNFOHPPO_00808	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
GNFOHPPO_00809	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
GNFOHPPO_00810	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
GNFOHPPO_00811	2.17e-135	ypjA	-	-	S	-	-	-	membrane
GNFOHPPO_00812	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
GNFOHPPO_00813	2.86e-289	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
GNFOHPPO_00814	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_00815	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
GNFOHPPO_00816	9.78e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GNFOHPPO_00817	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
GNFOHPPO_00818	1.83e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
GNFOHPPO_00819	3.63e-269	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
GNFOHPPO_00820	9.39e-277	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GNFOHPPO_00821	9.42e-232	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GNFOHPPO_00822	1.14e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GNFOHPPO_00823	3.44e-203	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GNFOHPPO_00824	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GNFOHPPO_00825	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GNFOHPPO_00826	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
GNFOHPPO_00827	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00828	1.46e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
GNFOHPPO_00829	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
GNFOHPPO_00830	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
GNFOHPPO_00831	5.92e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GNFOHPPO_00832	2.03e-116	ypoC	-	-	-	-	-	-	-
GNFOHPPO_00833	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GNFOHPPO_00834	8.84e-146	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GNFOHPPO_00835	3.19e-236	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
GNFOHPPO_00836	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
GNFOHPPO_00840	7.01e-83	yppG	-	-	S	-	-	-	YppG-like protein
GNFOHPPO_00841	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GNFOHPPO_00842	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
GNFOHPPO_00843	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GNFOHPPO_00844	6.67e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
GNFOHPPO_00846	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
GNFOHPPO_00847	1.33e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GNFOHPPO_00848	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GNFOHPPO_00849	2.32e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GNFOHPPO_00850	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
GNFOHPPO_00852	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
GNFOHPPO_00853	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GNFOHPPO_00854	2.85e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GNFOHPPO_00855	5.07e-298	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
GNFOHPPO_00856	2.52e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
GNFOHPPO_00857	1.8e-129	yrdC	-	-	Q	-	-	-	Isochorismatase family
GNFOHPPO_00858	3.39e-80	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
GNFOHPPO_00859	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
GNFOHPPO_00860	1.5e-64	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
GNFOHPPO_00861	8.15e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_00862	9.93e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
GNFOHPPO_00863	3.61e-117	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
GNFOHPPO_00864	0.0	ypbR	-	-	S	-	-	-	Dynamin family
GNFOHPPO_00865	8.23e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
GNFOHPPO_00866	2.44e-10	-	-	-	-	-	-	-	-
GNFOHPPO_00867	3.89e-209	ypcP	-	-	L	-	-	-	5'3' exonuclease
GNFOHPPO_00869	1.43e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
GNFOHPPO_00870	3.26e-153	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GNFOHPPO_00871	3.42e-158	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
GNFOHPPO_00872	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
GNFOHPPO_00873	1.13e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
GNFOHPPO_00874	1.27e-17	degR	-	-	-	-	-	-	-
GNFOHPPO_00875	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
GNFOHPPO_00876	1.56e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GNFOHPPO_00877	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GNFOHPPO_00878	3.93e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
GNFOHPPO_00879	7.66e-127	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
GNFOHPPO_00880	1.48e-199	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
GNFOHPPO_00881	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
GNFOHPPO_00882	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
GNFOHPPO_00883	2.46e-172	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
GNFOHPPO_00884	6.48e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
GNFOHPPO_00885	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GNFOHPPO_00886	3.01e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GNFOHPPO_00887	1.11e-146	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GNFOHPPO_00888	3.69e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
GNFOHPPO_00889	8.98e-228	yplP	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00890	1.73e-308	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GNFOHPPO_00891	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
GNFOHPPO_00892	2.96e-136	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GNFOHPPO_00893	1.49e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GNFOHPPO_00894	3.93e-126	ypmS	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_00895	3.35e-89	ypoP	-	-	K	-	-	-	transcriptional
GNFOHPPO_00896	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GNFOHPPO_00897	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GNFOHPPO_00898	6.74e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
GNFOHPPO_00899	2.23e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
GNFOHPPO_00900	1.83e-230	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
GNFOHPPO_00901	4.26e-88	cgeA	-	-	-	ko:K06319	-	ko00000	-
GNFOHPPO_00902	6.96e-64	cgeC	-	-	-	ko:K06321	-	ko00000	-
GNFOHPPO_00903	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
GNFOHPPO_00904	4.69e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
GNFOHPPO_00906	1.68e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
GNFOHPPO_00907	5.05e-314	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GNFOHPPO_00908	6.87e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GNFOHPPO_00909	2.68e-159	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GNFOHPPO_00910	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
GNFOHPPO_00911	1.99e-203	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
GNFOHPPO_00912	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
GNFOHPPO_00913	6.95e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
GNFOHPPO_00914	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GNFOHPPO_00915	1.9e-161	yodN	-	-	-	-	-	-	-
GNFOHPPO_00917	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
GNFOHPPO_00918	1.83e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
GNFOHPPO_00919	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
GNFOHPPO_00921	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
GNFOHPPO_00922	7.76e-193	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
GNFOHPPO_00923	1.68e-50	yodI	-	-	-	-	-	-	-
GNFOHPPO_00924	1.76e-165	yodH	-	-	Q	-	-	-	Methyltransferase
GNFOHPPO_00925	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
GNFOHPPO_00927	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GNFOHPPO_00928	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
GNFOHPPO_00929	2.56e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
GNFOHPPO_00930	2.08e-141	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
GNFOHPPO_00931	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
GNFOHPPO_00932	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
GNFOHPPO_00933	7.75e-26	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
GNFOHPPO_00934	3.67e-89	iolK	-	-	S	-	-	-	tautomerase
GNFOHPPO_00936	4.87e-106	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
GNFOHPPO_00937	1.03e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
GNFOHPPO_00938	1.05e-30	-	-	-	-	-	-	-	-
GNFOHPPO_00939	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
GNFOHPPO_00940	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
GNFOHPPO_00941	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GNFOHPPO_00942	1.19e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
GNFOHPPO_00944	9.47e-144	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GNFOHPPO_00945	2.86e-286	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
GNFOHPPO_00946	3.52e-292	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
GNFOHPPO_00947	2.65e-144	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GNFOHPPO_00948	1.2e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
GNFOHPPO_00949	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
GNFOHPPO_00950	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GNFOHPPO_00951	2.47e-261	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GNFOHPPO_00952	1.15e-182	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
GNFOHPPO_00953	9.85e-215	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
GNFOHPPO_00954	5.92e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GNFOHPPO_00955	4.76e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
GNFOHPPO_00956	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
GNFOHPPO_00957	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GNFOHPPO_00958	4.69e-43	yozC	-	-	-	-	-	-	-
GNFOHPPO_00960	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
GNFOHPPO_00961	6.36e-50	yocN	-	-	-	-	-	-	-
GNFOHPPO_00962	9.63e-60	yozN	-	-	-	-	-	-	-
GNFOHPPO_00963	3.13e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GNFOHPPO_00964	3.51e-13	yocN	-	-	-	-	-	-	-
GNFOHPPO_00965	1.92e-13	yocL	-	-	-	-	-	-	-
GNFOHPPO_00966	9.07e-79	yocK	-	-	T	-	-	-	general stress protein
GNFOHPPO_00968	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GNFOHPPO_00969	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
GNFOHPPO_00970	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
GNFOHPPO_00972	1.35e-240	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
GNFOHPPO_00973	1.6e-123	yocC	-	-	-	-	-	-	-
GNFOHPPO_00974	3.14e-182	-	-	-	J	-	-	-	Protein required for attachment to host cells
GNFOHPPO_00975	1.33e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
GNFOHPPO_00976	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GNFOHPPO_00977	7.69e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
GNFOHPPO_00978	1.57e-118	yobW	-	-	-	-	-	-	-
GNFOHPPO_00979	1.15e-173	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
GNFOHPPO_00980	4.57e-123	yobS	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_00981	1.24e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GNFOHPPO_00982	6.09e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
GNFOHPPO_00983	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
GNFOHPPO_00984	9.59e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
GNFOHPPO_00985	8.01e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
GNFOHPPO_00986	1.03e-87	ylbD	-	-	S	-	-	-	Putative coat protein
GNFOHPPO_00987	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
GNFOHPPO_00988	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
GNFOHPPO_00989	2.78e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
GNFOHPPO_00991	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
GNFOHPPO_00992	1.01e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GNFOHPPO_00993	1.68e-276	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
GNFOHPPO_00994	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
GNFOHPPO_00995	3.07e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GNFOHPPO_00996	1.43e-292	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GNFOHPPO_00997	4.88e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
GNFOHPPO_00998	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
GNFOHPPO_00999	3.13e-111	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GNFOHPPO_01000	3.26e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
GNFOHPPO_01001	2.29e-208	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFOHPPO_01002	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GNFOHPPO_01003	1.78e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GNFOHPPO_01004	4.08e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GNFOHPPO_01005	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
GNFOHPPO_01006	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GNFOHPPO_01007	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
GNFOHPPO_01008	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GNFOHPPO_01009	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GNFOHPPO_01010	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GNFOHPPO_01011	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GNFOHPPO_01012	5.69e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GNFOHPPO_01013	1.17e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
GNFOHPPO_01014	2.67e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GNFOHPPO_01015	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GNFOHPPO_01016	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GNFOHPPO_01017	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
GNFOHPPO_01018	2.64e-214	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GNFOHPPO_01019	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_01020	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_01021	1.97e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GNFOHPPO_01022	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
GNFOHPPO_01023	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
GNFOHPPO_01024	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
GNFOHPPO_01025	5.23e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GNFOHPPO_01026	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GNFOHPPO_01027	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
GNFOHPPO_01028	1.44e-180	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
GNFOHPPO_01029	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
GNFOHPPO_01030	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GNFOHPPO_01031	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
GNFOHPPO_01032	1.24e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GNFOHPPO_01033	4.4e-215	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GNFOHPPO_01034	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GNFOHPPO_01035	1.39e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
GNFOHPPO_01036	1.47e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GNFOHPPO_01037	9.71e-317	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GNFOHPPO_01038	3.09e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GNFOHPPO_01039	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
GNFOHPPO_01040	1.01e-180	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GNFOHPPO_01041	2.46e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GNFOHPPO_01042	3.66e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GNFOHPPO_01043	2.57e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GNFOHPPO_01045	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
GNFOHPPO_01046	4.72e-226	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
GNFOHPPO_01047	3.06e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
GNFOHPPO_01048	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
GNFOHPPO_01049	2.06e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
GNFOHPPO_01050	7.18e-188	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
GNFOHPPO_01051	6.27e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
GNFOHPPO_01052	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
GNFOHPPO_01053	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
GNFOHPPO_01054	2.14e-198	yloC	-	-	S	-	-	-	stress-induced protein
GNFOHPPO_01055	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
GNFOHPPO_01056	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GNFOHPPO_01057	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GNFOHPPO_01058	2.54e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GNFOHPPO_01059	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GNFOHPPO_01060	5e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GNFOHPPO_01061	4.76e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GNFOHPPO_01062	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GNFOHPPO_01063	8.79e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GNFOHPPO_01064	3.51e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GNFOHPPO_01065	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GNFOHPPO_01066	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GNFOHPPO_01067	1.24e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GNFOHPPO_01068	2.61e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GNFOHPPO_01069	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GNFOHPPO_01070	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_01071	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
GNFOHPPO_01072	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
GNFOHPPO_01073	3.97e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
GNFOHPPO_01074	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GNFOHPPO_01075	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GNFOHPPO_01076	7.38e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GNFOHPPO_01077	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_01078	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GNFOHPPO_01079	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GNFOHPPO_01080	6.09e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GNFOHPPO_01081	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GNFOHPPO_01082	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GNFOHPPO_01083	1.1e-184	-	-	-	S	-	-	-	Phosphotransferase enzyme family
GNFOHPPO_01084	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GNFOHPPO_01085	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GNFOHPPO_01086	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GNFOHPPO_01087	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
GNFOHPPO_01088	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
GNFOHPPO_01089	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GNFOHPPO_01090	8.4e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GNFOHPPO_01091	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GNFOHPPO_01092	7.24e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GNFOHPPO_01093	2.38e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GNFOHPPO_01094	0.0	ylqG	-	-	-	-	-	-	-
GNFOHPPO_01095	4.88e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
GNFOHPPO_01096	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GNFOHPPO_01097	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GNFOHPPO_01098	6.27e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
GNFOHPPO_01099	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GNFOHPPO_01100	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GNFOHPPO_01101	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
GNFOHPPO_01102	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GNFOHPPO_01103	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GNFOHPPO_01104	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GNFOHPPO_01105	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GNFOHPPO_01106	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
GNFOHPPO_01107	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
GNFOHPPO_01108	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
GNFOHPPO_01109	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GNFOHPPO_01110	2.29e-121	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
GNFOHPPO_01111	1.74e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GNFOHPPO_01112	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
GNFOHPPO_01113	1.39e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
GNFOHPPO_01114	3e-260	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
GNFOHPPO_01115	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
GNFOHPPO_01116	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
GNFOHPPO_01117	1.89e-80	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
GNFOHPPO_01118	7.71e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GNFOHPPO_01119	1.26e-249	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GNFOHPPO_01120	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
GNFOHPPO_01121	2.2e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
GNFOHPPO_01122	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
GNFOHPPO_01123	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
GNFOHPPO_01124	1.64e-167	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
GNFOHPPO_01125	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GNFOHPPO_01126	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GNFOHPPO_01127	7.58e-246	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
GNFOHPPO_01128	4.28e-198	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
GNFOHPPO_01129	4.97e-249	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GNFOHPPO_01130	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
GNFOHPPO_01131	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
GNFOHPPO_01132	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GNFOHPPO_01133	1.65e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GNFOHPPO_01134	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_01135	3.01e-92	ylxL	-	-	-	-	-	-	-
GNFOHPPO_01136	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GNFOHPPO_01137	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GNFOHPPO_01138	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GNFOHPPO_01139	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GNFOHPPO_01140	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GNFOHPPO_01141	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GNFOHPPO_01142	1.55e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GNFOHPPO_01143	1.15e-296	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GNFOHPPO_01144	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GNFOHPPO_01145	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GNFOHPPO_01146	5.66e-106	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GNFOHPPO_01147	1.35e-262	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GNFOHPPO_01148	9.61e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
GNFOHPPO_01149	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
GNFOHPPO_01150	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GNFOHPPO_01151	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
GNFOHPPO_01152	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GNFOHPPO_01153	2.87e-218	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GNFOHPPO_01154	3.69e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GNFOHPPO_01155	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GNFOHPPO_01156	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GNFOHPPO_01157	3.56e-233	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
GNFOHPPO_01158	2.06e-299	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
GNFOHPPO_01159	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
GNFOHPPO_01160	3.31e-206	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
GNFOHPPO_01161	4.75e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GNFOHPPO_01162	1e-248	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GNFOHPPO_01163	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GNFOHPPO_01164	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GNFOHPPO_01165	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GNFOHPPO_01166	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
GNFOHPPO_01167	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
GNFOHPPO_01168	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GNFOHPPO_01169	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_01170	9.04e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_01171	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_01172	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
GNFOHPPO_01173	1.6e-306	albE	-	-	S	-	-	-	Peptidase M16
GNFOHPPO_01174	1.01e-310	ymfH	-	-	S	-	-	-	zinc protease
GNFOHPPO_01175	8.62e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GNFOHPPO_01176	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
GNFOHPPO_01177	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
GNFOHPPO_01178	1.17e-178	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
GNFOHPPO_01179	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GNFOHPPO_01180	1.55e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
GNFOHPPO_01181	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GNFOHPPO_01182	7.76e-279	pbpX	-	-	V	-	-	-	Beta-lactamase
GNFOHPPO_01183	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GNFOHPPO_01184	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
GNFOHPPO_01185	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
GNFOHPPO_01186	8.3e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GNFOHPPO_01187	1.23e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GNFOHPPO_01188	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GNFOHPPO_01189	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
GNFOHPPO_01190	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
GNFOHPPO_01191	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GNFOHPPO_01192	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GNFOHPPO_01193	6.45e-41	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFOHPPO_01194	0.000561	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFOHPPO_01195	3.97e-49	-	-	-	-	-	-	-	-
GNFOHPPO_01197	6.72e-165	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
GNFOHPPO_01198	4.05e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_01199	1.29e-233	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
GNFOHPPO_01200	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_01201	5.27e-49	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
GNFOHPPO_01202	4.24e-308	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
GNFOHPPO_01203	9.1e-189	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
GNFOHPPO_01204	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
GNFOHPPO_01205	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
GNFOHPPO_01206	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_01207	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_01208	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
GNFOHPPO_01209	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
GNFOHPPO_01210	1.38e-293	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
GNFOHPPO_01211	1.74e-101	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
GNFOHPPO_01212	1.28e-152	yoaK	-	-	S	-	-	-	Membrane
GNFOHPPO_01213	2.78e-82	ymzB	-	-	-	-	-	-	-
GNFOHPPO_01214	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
GNFOHPPO_01215	3.03e-06	-	-	-	-	-	-	-	-
GNFOHPPO_01216	6.85e-164	ymaC	-	-	S	-	-	-	Replication protein
GNFOHPPO_01217	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
GNFOHPPO_01218	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
GNFOHPPO_01219	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
GNFOHPPO_01221	2.43e-76	ymaF	-	-	S	-	-	-	YmaF family
GNFOHPPO_01222	7.63e-221	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GNFOHPPO_01223	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GNFOHPPO_01224	6e-59	-	-	-	-	-	-	-	-
GNFOHPPO_01225	9.42e-29	ymzA	-	-	-	-	-	-	-
GNFOHPPO_01226	1.61e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
GNFOHPPO_01227	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GNFOHPPO_01228	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GNFOHPPO_01229	2.72e-142	ymaB	-	-	S	-	-	-	MutT family
GNFOHPPO_01230	3.22e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
GNFOHPPO_01231	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
GNFOHPPO_01232	5.44e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GNFOHPPO_01233	2.77e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GNFOHPPO_01234	5.34e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
GNFOHPPO_01235	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GNFOHPPO_01236	3.5e-274	mrjp	-	-	G	-	-	-	Major royal jelly protein
GNFOHPPO_01237	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
GNFOHPPO_01238	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
GNFOHPPO_01239	2.22e-278	xylR	-	-	GK	-	-	-	ROK family
GNFOHPPO_01240	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
GNFOHPPO_01241	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
GNFOHPPO_01242	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
GNFOHPPO_01245	2.21e-27	-	-	-	-	-	-	-	-
GNFOHPPO_01246	1.77e-238	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GNFOHPPO_01247	4.09e-06	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
GNFOHPPO_01248	4.33e-185	yoaP	-	-	K	-	-	-	YoaP-like
GNFOHPPO_01249	1.97e-129	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_01250	8.94e-85	-	-	-	-	-	-	-	-
GNFOHPPO_01252	1.21e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
GNFOHPPO_01253	4.15e-258	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_01254	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
GNFOHPPO_01255	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
GNFOHPPO_01256	1.5e-82	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GNFOHPPO_01257	1.83e-124	yvgO	-	-	-	-	-	-	-
GNFOHPPO_01259	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
GNFOHPPO_01260	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
GNFOHPPO_01261	3.51e-185	yndL	-	-	S	-	-	-	Replication protein
GNFOHPPO_01262	1.74e-11	-	-	-	-	-	-	-	-
GNFOHPPO_01263	6.29e-185	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
GNFOHPPO_01264	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
GNFOHPPO_01266	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GNFOHPPO_01267	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GNFOHPPO_01268	5.22e-145	yneB	-	-	L	-	-	-	resolvase
GNFOHPPO_01269	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
GNFOHPPO_01270	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GNFOHPPO_01271	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
GNFOHPPO_01272	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
GNFOHPPO_01273	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
GNFOHPPO_01274	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
GNFOHPPO_01275	2.47e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
GNFOHPPO_01276	3.22e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
GNFOHPPO_01277	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
GNFOHPPO_01278	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
GNFOHPPO_01279	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
GNFOHPPO_01280	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
GNFOHPPO_01281	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GNFOHPPO_01282	9.94e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNFOHPPO_01284	1.48e-45	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
GNFOHPPO_01285	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
GNFOHPPO_01286	4.68e-71	yneQ	-	-	-	-	-	-	-
GNFOHPPO_01287	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
GNFOHPPO_01288	9.09e-121	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GNFOHPPO_01289	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
GNFOHPPO_01290	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GNFOHPPO_01291	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GNFOHPPO_01292	3.14e-19	-	-	-	-	-	-	-	-
GNFOHPPO_01293	1.82e-63	ynfC	-	-	-	-	-	-	-
GNFOHPPO_01294	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
GNFOHPPO_01295	2.49e-228	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
GNFOHPPO_01296	1.03e-242	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
GNFOHPPO_01297	1.51e-146	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
GNFOHPPO_01298	6.29e-268	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
GNFOHPPO_01299	6.12e-193	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_01300	7.45e-233	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
GNFOHPPO_01301	2.17e-284	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
GNFOHPPO_01302	3.08e-203	yndG	-	-	S	-	-	-	DoxX-like family
GNFOHPPO_01303	1.11e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
GNFOHPPO_01304	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
GNFOHPPO_01305	1.53e-05	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
GNFOHPPO_01306	3.29e-276	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
GNFOHPPO_01307	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
GNFOHPPO_01308	1.48e-69	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
GNFOHPPO_01309	1.15e-312	-	-	-	T	-	-	-	Histidine kinase
GNFOHPPO_01310	3.79e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
GNFOHPPO_01311	5.9e-316	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
GNFOHPPO_01312	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
GNFOHPPO_01313	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01314	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01315	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01316	3.21e-286	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_01317	4.1e-178	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GNFOHPPO_01318	4.5e-157	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GNFOHPPO_01319	8.91e-162	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GNFOHPPO_01320	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
GNFOHPPO_01321	2.74e-286	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
GNFOHPPO_01322	1.94e-247	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GNFOHPPO_01323	1.24e-165	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GNFOHPPO_01324	9.71e-274	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GNFOHPPO_01325	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GNFOHPPO_01326	1.98e-187	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GNFOHPPO_01327	2.26e-95	yngA	-	-	S	-	-	-	membrane
GNFOHPPO_01328	4.35e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GNFOHPPO_01329	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_01330	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GNFOHPPO_01331	4.99e-178	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
GNFOHPPO_01332	1.48e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
GNFOHPPO_01333	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
GNFOHPPO_01334	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
GNFOHPPO_01335	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GNFOHPPO_01336	1.08e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
GNFOHPPO_01337	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
GNFOHPPO_01338	1.67e-85	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
GNFOHPPO_01339	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
GNFOHPPO_01340	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01343	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GNFOHPPO_01344	9.07e-234	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
GNFOHPPO_01345	5.91e-112	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
GNFOHPPO_01346	4.41e-214	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
GNFOHPPO_01347	0.0	ybeC	-	-	E	-	-	-	amino acid
GNFOHPPO_01348	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01349	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
GNFOHPPO_01350	4.25e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
GNFOHPPO_01351	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
GNFOHPPO_01352	7.66e-153	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
GNFOHPPO_01353	5.89e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
GNFOHPPO_01354	1.58e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
GNFOHPPO_01355	8.31e-126	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
GNFOHPPO_01357	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
GNFOHPPO_01360	1.94e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GNFOHPPO_01361	1.61e-154	ydhC	-	-	K	-	-	-	FCD
GNFOHPPO_01362	3.56e-211	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
GNFOHPPO_01363	4.68e-188	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
GNFOHPPO_01364	1.58e-145	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GNFOHPPO_01365	3.64e-191	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GNFOHPPO_01366	6.15e-195	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GNFOHPPO_01367	1.46e-106	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
GNFOHPPO_01368	9e-158	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GNFOHPPO_01369	1.84e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFOHPPO_01370	1.17e-289	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GNFOHPPO_01371	2.75e-268	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
GNFOHPPO_01372	3.98e-250	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
GNFOHPPO_01373	3.51e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_01374	3.86e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_01375	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
GNFOHPPO_01376	6.72e-171	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
GNFOHPPO_01377	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
GNFOHPPO_01378	1.19e-143	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_01379	3.62e-277	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_01380	3.42e-91	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GNFOHPPO_01381	6.32e-95	-	-	-	GK	-	-	-	Transcriptional regulator
GNFOHPPO_01382	1.8e-135	-	-	-	G	-	-	-	Major Facilitator Superfamily
GNFOHPPO_01383	4.04e-48	yraG	-	-	-	ko:K06440	-	ko00000	-
GNFOHPPO_01384	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
GNFOHPPO_01385	7.17e-281	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GNFOHPPO_01386	3.54e-35	yraE	-	-	-	ko:K06440	-	ko00000	-
GNFOHPPO_01387	5.95e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
GNFOHPPO_01388	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GNFOHPPO_01389	1.29e-202	ydeK	-	-	EG	-	-	-	-transporter
GNFOHPPO_01390	2.43e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01391	1.85e-251	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
GNFOHPPO_01392	5.22e-137	-	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_01393	1.15e-239	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
GNFOHPPO_01394	3.03e-159	-	-	-	T	-	-	-	Transcriptional regulator
GNFOHPPO_01395	1.82e-129	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
GNFOHPPO_01397	1.4e-144	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_01398	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
GNFOHPPO_01399	3.43e-282	nhaC_1	-	-	C	-	-	-	antiporter
GNFOHPPO_01400	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
GNFOHPPO_01401	1.1e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
GNFOHPPO_01402	2.35e-218	-	-	-	S	-	-	-	Sodium Bile acid symporter family
GNFOHPPO_01403	1.69e-298	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
GNFOHPPO_01404	4.49e-192	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GNFOHPPO_01405	7.51e-190	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
GNFOHPPO_01406	3.24e-249	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GNFOHPPO_01407	1.06e-109	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
GNFOHPPO_01408	3.17e-75	ydeH	-	-	-	-	-	-	-
GNFOHPPO_01409	2.49e-255	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
GNFOHPPO_01411	1.22e-190	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
GNFOHPPO_01413	6.35e-256	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
GNFOHPPO_01414	1.37e-218	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
GNFOHPPO_01415	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
GNFOHPPO_01418	1.05e-84	-	-	-	G	-	-	-	Cupin domain
GNFOHPPO_01419	2.49e-110	-	-	-	S	-	-	-	DinB superfamily
GNFOHPPO_01420	1.24e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
GNFOHPPO_01421	2.73e-300	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_01422	1.13e-220	ybfA	-	-	K	-	-	-	FR47-like protein
GNFOHPPO_01423	1.94e-66	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
GNFOHPPO_01424	3.23e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
GNFOHPPO_01425	2.02e-75	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GNFOHPPO_01426	7.2e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
GNFOHPPO_01427	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
GNFOHPPO_01428	2.67e-251	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
GNFOHPPO_01429	7.6e-221	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GNFOHPPO_01430	1.92e-145	-	-	-	C	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_01431	1.39e-114	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
GNFOHPPO_01433	5.69e-147	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
GNFOHPPO_01434	1.59e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01435	8.17e-83	-	-	-	S	-	-	-	YjbR
GNFOHPPO_01436	2.05e-94	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
GNFOHPPO_01437	2.06e-44	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
GNFOHPPO_01438	9.33e-39	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
GNFOHPPO_01439	6.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01440	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
GNFOHPPO_01441	5.49e-124	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
GNFOHPPO_01442	3.94e-126	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GNFOHPPO_01443	1.76e-101	-	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01444	2.11e-38	-	-	-	S	-	-	-	Doxx family
GNFOHPPO_01453	1.22e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GNFOHPPO_01454	1.78e-21	-	-	-	-	-	-	-	-
GNFOHPPO_01455	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
GNFOHPPO_01456	5.75e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
GNFOHPPO_01457	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_01458	5.84e-110	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GNFOHPPO_01459	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
GNFOHPPO_01460	2.17e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
GNFOHPPO_01461	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GNFOHPPO_01462	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
GNFOHPPO_01463	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
GNFOHPPO_01464	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
GNFOHPPO_01465	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GNFOHPPO_01466	4e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GNFOHPPO_01467	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
GNFOHPPO_01468	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GNFOHPPO_01469	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
GNFOHPPO_01470	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
GNFOHPPO_01471	6.83e-109	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
GNFOHPPO_01472	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GNFOHPPO_01473	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GNFOHPPO_01474	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GNFOHPPO_01475	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
GNFOHPPO_01476	1.64e-159	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNFOHPPO_01477	6.58e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
GNFOHPPO_01478	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
GNFOHPPO_01479	5.29e-262	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
GNFOHPPO_01480	2.29e-70	ydbL	-	-	-	-	-	-	-
GNFOHPPO_01481	9.93e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GNFOHPPO_01482	1.13e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_01483	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
GNFOHPPO_01484	3.21e-286	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GNFOHPPO_01485	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
GNFOHPPO_01486	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
GNFOHPPO_01487	1.82e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GNFOHPPO_01488	6.68e-199	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
GNFOHPPO_01489	4.28e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
GNFOHPPO_01490	7.68e-84	ydbB	-	-	G	-	-	-	Cupin domain
GNFOHPPO_01491	2.34e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
GNFOHPPO_01492	5.39e-182	ydbA	-	-	P	-	-	-	EcsC protein family
GNFOHPPO_01493	1.42e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
GNFOHPPO_01494	1.86e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
GNFOHPPO_01495	1.95e-45	ydaT	-	-	-	-	-	-	-
GNFOHPPO_01497	2.28e-289	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GNFOHPPO_01498	2.14e-53	-	-	-	-	-	-	-	-
GNFOHPPO_01499	9.95e-129	-	-	-	-	-	-	-	-
GNFOHPPO_01500	6.21e-115	-	-	-	-	-	-	-	-
GNFOHPPO_01502	1.49e-26	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GNFOHPPO_01503	9.15e-17	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
GNFOHPPO_01504	1.89e-139	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GNFOHPPO_01505	1.25e-45	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
GNFOHPPO_01506	1.66e-49	xkdQ	-	-	G	-	-	-	NLP P60 protein
GNFOHPPO_01508	2.86e-77	-	-	-	K	-	-	-	acetyltransferase
GNFOHPPO_01509	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GNFOHPPO_01510	5.33e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
GNFOHPPO_01511	0.0	ydaO	-	-	E	-	-	-	amino acid
GNFOHPPO_01513	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
GNFOHPPO_01514	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
GNFOHPPO_01515	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
GNFOHPPO_01516	6.56e-190	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
GNFOHPPO_01517	1.15e-257	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GNFOHPPO_01518	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GNFOHPPO_01519	7.97e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
GNFOHPPO_01520	6.54e-63	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
GNFOHPPO_01521	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GNFOHPPO_01522	1.83e-101	ydaG	-	-	S	-	-	-	general stress protein
GNFOHPPO_01523	5.51e-147	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GNFOHPPO_01524	1.17e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
GNFOHPPO_01525	1.89e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_01526	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
GNFOHPPO_01527	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
GNFOHPPO_01528	1.55e-222	ycsN	-	-	S	-	-	-	Oxidoreductase
GNFOHPPO_01529	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
GNFOHPPO_01530	2e-73	yczJ	-	-	S	-	-	-	biosynthesis
GNFOHPPO_01532	6.66e-151	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
GNFOHPPO_01533	3.99e-168	kipR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01534	1.03e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
GNFOHPPO_01535	3.99e-176	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
GNFOHPPO_01536	7.21e-194	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
GNFOHPPO_01537	4.6e-272	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
GNFOHPPO_01538	6.12e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
GNFOHPPO_01539	4.66e-178	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
GNFOHPPO_01541	8.28e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
GNFOHPPO_01542	5.74e-264	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
GNFOHPPO_01543	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GNFOHPPO_01544	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
GNFOHPPO_01545	9.6e-73	-	-	-	-	-	-	-	-
GNFOHPPO_01546	3.5e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
GNFOHPPO_01547	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
GNFOHPPO_01548	5.88e-131	ycnI	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_01549	1.19e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_01550	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
GNFOHPPO_01551	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GNFOHPPO_01552	7.59e-288	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GNFOHPPO_01553	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GNFOHPPO_01554	1.94e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GNFOHPPO_01555	1.97e-59	ycnE	-	-	S	-	-	-	Monooxygenase
GNFOHPPO_01556	1.38e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
GNFOHPPO_01557	7.09e-194	ycnC	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01558	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
GNFOHPPO_01559	6.82e-224	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
GNFOHPPO_01560	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_01561	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_01562	7.78e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_01563	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GNFOHPPO_01565	1.2e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
GNFOHPPO_01566	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
GNFOHPPO_01567	9.08e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_01568	8.13e-306	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
GNFOHPPO_01569	6.34e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
GNFOHPPO_01570	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
GNFOHPPO_01571	1.97e-276	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
GNFOHPPO_01572	1.32e-168	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_01573	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
GNFOHPPO_01574	6.34e-183	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
GNFOHPPO_01575	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFOHPPO_01576	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_01577	5.34e-248	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
GNFOHPPO_01578	8.42e-302	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
GNFOHPPO_01579	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
GNFOHPPO_01581	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
GNFOHPPO_01582	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
GNFOHPPO_01583	8.28e-101	yclD	-	-	-	-	-	-	-
GNFOHPPO_01584	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
GNFOHPPO_01585	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GNFOHPPO_01586	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GNFOHPPO_01587	4.02e-204	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
GNFOHPPO_01588	2.8e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
GNFOHPPO_01589	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
GNFOHPPO_01590	1.18e-170	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
GNFOHPPO_01591	3.11e-144	yczE	-	-	S	ko:K07149	-	ko00000	membrane
GNFOHPPO_01592	1.51e-166	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
GNFOHPPO_01593	1.72e-315	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
GNFOHPPO_01594	1.59e-216	ycxC	-	-	EG	-	-	-	EamA-like transporter family
GNFOHPPO_01596	1.95e-85	-	-	-	S	-	-	-	YcxB-like protein
GNFOHPPO_01597	1.91e-316	-	-	-	E	-	-	-	Aminotransferase class I and II
GNFOHPPO_01598	3.05e-180	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
GNFOHPPO_01599	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
GNFOHPPO_01600	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01601	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_01602	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
GNFOHPPO_01603	3.14e-139	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
GNFOHPPO_01604	2.56e-123	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
GNFOHPPO_01605	1.09e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
GNFOHPPO_01606	3.78e-88	nin	-	-	S	-	-	-	Competence protein J (ComJ)
GNFOHPPO_01607	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GNFOHPPO_01608	3.31e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
GNFOHPPO_01609	2.67e-96	yckC	-	-	S	-	-	-	membrane
GNFOHPPO_01610	2.5e-281	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GNFOHPPO_01611	1.36e-287	yciC	-	-	S	-	-	-	GTPases (G3E family)
GNFOHPPO_01612	2.01e-285	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
GNFOHPPO_01613	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
GNFOHPPO_01614	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GNFOHPPO_01615	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GNFOHPPO_01616	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
GNFOHPPO_01617	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
GNFOHPPO_01618	4.06e-243	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GNFOHPPO_01619	2.37e-289	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
GNFOHPPO_01620	1.53e-304	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GNFOHPPO_01621	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
GNFOHPPO_01622	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
GNFOHPPO_01623	2.23e-191	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
GNFOHPPO_01624	1.15e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
GNFOHPPO_01625	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GNFOHPPO_01626	1.59e-302	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_01627	2.99e-176	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
GNFOHPPO_01628	2.47e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
GNFOHPPO_01629	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GNFOHPPO_01630	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
GNFOHPPO_01631	5.64e-315	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_01632	1.4e-190	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
GNFOHPPO_01633	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
GNFOHPPO_01634	6.92e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_01635	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
GNFOHPPO_01636	4.64e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GNFOHPPO_01637	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
GNFOHPPO_01638	3.78e-107	ycgB	-	-	-	-	-	-	-
GNFOHPPO_01639	2.68e-292	ycgA	-	-	S	-	-	-	Membrane
GNFOHPPO_01640	1.13e-270	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
GNFOHPPO_01641	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
GNFOHPPO_01642	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
GNFOHPPO_01643	7.71e-294	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
GNFOHPPO_01644	3.68e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
GNFOHPPO_01645	1.17e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
GNFOHPPO_01646	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
GNFOHPPO_01647	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
GNFOHPPO_01648	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
GNFOHPPO_01649	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
GNFOHPPO_01650	1.16e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
GNFOHPPO_01651	9.86e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_01652	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GNFOHPPO_01653	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GNFOHPPO_01654	1.81e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GNFOHPPO_01655	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
GNFOHPPO_01656	3.14e-181	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_01657	9.98e-249	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
GNFOHPPO_01658	3.62e-121	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
GNFOHPPO_01659	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_01660	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_01661	4.81e-228	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
GNFOHPPO_01662	7.62e-219	yccK	-	-	C	-	-	-	Aldo keto reductase
GNFOHPPO_01663	2.38e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
GNFOHPPO_01664	5.23e-144	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GNFOHPPO_01665	5.87e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GNFOHPPO_01666	6.28e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
GNFOHPPO_01667	5.62e-310	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
GNFOHPPO_01668	1.47e-267	ycbU	-	-	E	-	-	-	Selenocysteine lyase
GNFOHPPO_01669	9.85e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GNFOHPPO_01670	1.17e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GNFOHPPO_01671	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GNFOHPPO_01672	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
GNFOHPPO_01673	1.33e-104	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
GNFOHPPO_01674	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
GNFOHPPO_01675	1.32e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
GNFOHPPO_01676	9.37e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
GNFOHPPO_01677	2.15e-235	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
GNFOHPPO_01678	6.96e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
GNFOHPPO_01679	2.59e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNFOHPPO_01680	3.06e-40	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
GNFOHPPO_01681	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
GNFOHPPO_01682	1.26e-278	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_01683	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GNFOHPPO_01684	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
GNFOHPPO_01685	2.14e-232	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
GNFOHPPO_01686	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GNFOHPPO_01687	2.91e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
GNFOHPPO_01688	3.34e-271	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GNFOHPPO_01689	3.33e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
GNFOHPPO_01690	2.58e-56	ybfN	-	-	-	-	-	-	-
GNFOHPPO_01691	7.49e-195	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GNFOHPPO_01692	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_01693	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GNFOHPPO_01694	1.61e-271	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GNFOHPPO_01695	6.37e-257	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
GNFOHPPO_01696	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFOHPPO_01697	2.44e-45	-	-	-	-	-	-	-	-
GNFOHPPO_01698	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
GNFOHPPO_01700	1.17e-266	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
GNFOHPPO_01701	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
GNFOHPPO_01702	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
GNFOHPPO_01703	1.04e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
GNFOHPPO_01706	8.01e-65	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GNFOHPPO_01708	0.0	ybeC	-	-	E	-	-	-	amino acid
GNFOHPPO_01709	7.84e-55	ybyB	-	-	-	-	-	-	-
GNFOHPPO_01710	4.34e-145	yqeB	-	-	-	-	-	-	-
GNFOHPPO_01711	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
GNFOHPPO_01712	7.39e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
GNFOHPPO_01713	9.56e-35	-	-	-	-	-	-	-	-
GNFOHPPO_01714	2.78e-254	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GNFOHPPO_01715	1.16e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
GNFOHPPO_01716	2.64e-215	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
GNFOHPPO_01717	1.5e-143	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
GNFOHPPO_01718	3.85e-259	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
GNFOHPPO_01719	5.32e-119	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GNFOHPPO_01720	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_01721	1.68e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_01722	2e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
GNFOHPPO_01723	7.37e-136	yxaC	-	-	M	-	-	-	effector of murein hydrolase
GNFOHPPO_01724	6.23e-208	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
GNFOHPPO_01725	3.56e-118	-	-	-	H	-	-	-	Tellurite resistance protein TehB
GNFOHPPO_01727	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
GNFOHPPO_01728	1.73e-139	-	-	-	S	-	-	-	ABC-2 family transporter protein
GNFOHPPO_01729	5.03e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GNFOHPPO_01730	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GNFOHPPO_01731	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GNFOHPPO_01732	5.88e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_01733	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GNFOHPPO_01734	1.11e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GNFOHPPO_01735	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_01741	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
GNFOHPPO_01742	6.11e-111	ybbJ	-	-	J	-	-	-	acetyltransferase
GNFOHPPO_01743	1.4e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GNFOHPPO_01744	4.31e-312	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_01745	3.25e-311	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
GNFOHPPO_01746	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
GNFOHPPO_01747	4.71e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_01748	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
GNFOHPPO_01749	1.73e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
GNFOHPPO_01750	2.19e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_01751	1.95e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_01752	1.72e-146	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
GNFOHPPO_01753	1.54e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
GNFOHPPO_01754	1.36e-288	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
GNFOHPPO_01755	2.3e-255	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
GNFOHPPO_01756	2.31e-232	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
GNFOHPPO_01757	1.27e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GNFOHPPO_01758	6.41e-281	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
GNFOHPPO_01759	4.07e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
GNFOHPPO_01760	1.19e-149	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
GNFOHPPO_01761	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GNFOHPPO_01762	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GNFOHPPO_01763	2.84e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GNFOHPPO_01764	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
GNFOHPPO_01765	9.98e-161	ygaZ	-	-	E	-	-	-	AzlC protein
GNFOHPPO_01766	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01767	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNFOHPPO_01768	2.49e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GNFOHPPO_01770	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
GNFOHPPO_01772	1.11e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GNFOHPPO_01773	1.63e-69	-	-	-	UW	ko:K06236,ko:K07061	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165	ko00000,ko00001,ko00536,ko02048,ko04516	Hep Hag repeat protein
GNFOHPPO_01775	1.06e-121	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
GNFOHPPO_01776	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GNFOHPPO_01777	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GNFOHPPO_01778	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
GNFOHPPO_01779	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
GNFOHPPO_01780	1.98e-140	yttP	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01781	2.16e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GNFOHPPO_01782	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GNFOHPPO_01783	1.96e-308	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GNFOHPPO_01784	1.93e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
GNFOHPPO_01785	1.47e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GNFOHPPO_01786	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
GNFOHPPO_01787	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GNFOHPPO_01788	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
GNFOHPPO_01789	2.71e-195	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GNFOHPPO_01790	7.46e-234	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
GNFOHPPO_01791	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
GNFOHPPO_01792	1.81e-156	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
GNFOHPPO_01793	1.37e-99	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
GNFOHPPO_01794	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GNFOHPPO_01795	3.18e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
GNFOHPPO_01796	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GNFOHPPO_01797	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
GNFOHPPO_01798	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
GNFOHPPO_01799	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
GNFOHPPO_01801	3.41e-183	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_01802	4.16e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
GNFOHPPO_01803	6.77e-305	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
GNFOHPPO_01804	1.2e-60	ytpI	-	-	S	-	-	-	YtpI-like protein
GNFOHPPO_01805	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
GNFOHPPO_01806	4.08e-31	-	-	-	-	-	-	-	-
GNFOHPPO_01807	2.64e-114	ytrI	-	-	-	-	-	-	-
GNFOHPPO_01808	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
GNFOHPPO_01809	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GNFOHPPO_01810	1.72e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
GNFOHPPO_01811	3.59e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GNFOHPPO_01812	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GNFOHPPO_01813	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GNFOHPPO_01814	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GNFOHPPO_01815	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
GNFOHPPO_01816	9.96e-248	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
GNFOHPPO_01817	1.14e-95	ytwI	-	-	S	-	-	-	membrane
GNFOHPPO_01818	5.5e-83	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
GNFOHPPO_01819	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
GNFOHPPO_01820	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
GNFOHPPO_01821	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
GNFOHPPO_01822	2.9e-167	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_01823	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
GNFOHPPO_01824	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GNFOHPPO_01825	9.47e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GNFOHPPO_01826	1.16e-137	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
GNFOHPPO_01827	4.17e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GNFOHPPO_01828	5.53e-206	ytbE	-	-	S	-	-	-	reductase
GNFOHPPO_01829	2.79e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
GNFOHPPO_01830	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_01831	2.19e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GNFOHPPO_01832	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GNFOHPPO_01833	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GNFOHPPO_01834	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
GNFOHPPO_01835	3e-200	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GNFOHPPO_01836	5.42e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_01837	2.32e-196	ytxC	-	-	S	-	-	-	YtxC-like family
GNFOHPPO_01838	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GNFOHPPO_01839	4.17e-193	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
GNFOHPPO_01840	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_01841	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
GNFOHPPO_01842	2.76e-69	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
GNFOHPPO_01843	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GNFOHPPO_01844	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GNFOHPPO_01845	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GNFOHPPO_01846	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GNFOHPPO_01847	1.1e-55	ysdA	-	-	S	-	-	-	Membrane
GNFOHPPO_01848	9.71e-90	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
GNFOHPPO_01849	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
GNFOHPPO_01850	6.97e-241	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
GNFOHPPO_01851	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
GNFOHPPO_01852	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
GNFOHPPO_01853	2.82e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GNFOHPPO_01854	7.52e-182	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
GNFOHPPO_01855	1.16e-285	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GNFOHPPO_01856	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
GNFOHPPO_01857	4.38e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
GNFOHPPO_01858	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
GNFOHPPO_01859	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
GNFOHPPO_01860	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
GNFOHPPO_01861	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
GNFOHPPO_01862	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
GNFOHPPO_01863	1.25e-261	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
GNFOHPPO_01864	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
GNFOHPPO_01865	1.55e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNFOHPPO_01866	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GNFOHPPO_01867	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GNFOHPPO_01868	3.08e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GNFOHPPO_01869	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GNFOHPPO_01870	3.5e-108	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
GNFOHPPO_01871	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
GNFOHPPO_01872	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GNFOHPPO_01873	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
GNFOHPPO_01874	5.69e-162	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
GNFOHPPO_01875	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GNFOHPPO_01876	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_01877	1.01e-177	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
GNFOHPPO_01878	3.52e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
GNFOHPPO_01879	1.75e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
GNFOHPPO_01880	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
GNFOHPPO_01881	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GNFOHPPO_01882	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GNFOHPPO_01883	1.01e-273	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GNFOHPPO_01884	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GNFOHPPO_01885	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
GNFOHPPO_01886	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
GNFOHPPO_01887	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
GNFOHPPO_01888	3.79e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
GNFOHPPO_01889	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_01890	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_01891	4.68e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GNFOHPPO_01892	7.73e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
GNFOHPPO_01893	2.38e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GNFOHPPO_01894	3.2e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GNFOHPPO_01895	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
GNFOHPPO_01900	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
GNFOHPPO_01901	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
GNFOHPPO_01902	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GNFOHPPO_01903	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GNFOHPPO_01904	2.9e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GNFOHPPO_01905	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GNFOHPPO_01906	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GNFOHPPO_01907	9.54e-241	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
GNFOHPPO_01908	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GNFOHPPO_01909	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GNFOHPPO_01910	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
GNFOHPPO_01911	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GNFOHPPO_01912	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GNFOHPPO_01913	6.8e-115	ysxD	-	-	-	-	-	-	-
GNFOHPPO_01914	1.82e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GNFOHPPO_01915	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
GNFOHPPO_01916	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GNFOHPPO_01917	4.65e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
GNFOHPPO_01918	4.87e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
GNFOHPPO_01919	3.13e-310	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
GNFOHPPO_01920	8.26e-288	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
GNFOHPPO_01921	1.55e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GNFOHPPO_01922	1.53e-35	-	-	-	-	-	-	-	-
GNFOHPPO_01923	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GNFOHPPO_01924	1.32e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GNFOHPPO_01925	5.18e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GNFOHPPO_01926	5.38e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
GNFOHPPO_01927	2.36e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
GNFOHPPO_01928	7.15e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
GNFOHPPO_01929	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
GNFOHPPO_01930	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GNFOHPPO_01931	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
GNFOHPPO_01932	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GNFOHPPO_01933	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
GNFOHPPO_01934	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
GNFOHPPO_01935	5.1e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
GNFOHPPO_01936	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GNFOHPPO_01937	5.78e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
GNFOHPPO_01938	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GNFOHPPO_01939	3.64e-140	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
GNFOHPPO_01940	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GNFOHPPO_01941	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
GNFOHPPO_01942	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
GNFOHPPO_01943	1.23e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
GNFOHPPO_01944	2.33e-284	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
GNFOHPPO_01945	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
GNFOHPPO_01946	3.3e-199	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
GNFOHPPO_01947	6.04e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GNFOHPPO_01948	7.23e-256	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
GNFOHPPO_01949	1.1e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GNFOHPPO_01951	1.47e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
GNFOHPPO_01952	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GNFOHPPO_01953	3.57e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GNFOHPPO_01954	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
GNFOHPPO_01955	4.96e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GNFOHPPO_01956	2.01e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GNFOHPPO_01957	2.09e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
GNFOHPPO_01958	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
GNFOHPPO_01959	1.37e-141	yrbG	-	-	S	-	-	-	membrane
GNFOHPPO_01960	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_01961	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
GNFOHPPO_01962	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GNFOHPPO_01963	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
GNFOHPPO_01964	4.68e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
GNFOHPPO_01965	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GNFOHPPO_01966	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GNFOHPPO_01967	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GNFOHPPO_01968	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GNFOHPPO_01969	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
GNFOHPPO_01972	7.06e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GNFOHPPO_01973	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GNFOHPPO_01974	2.39e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GNFOHPPO_01975	9.19e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GNFOHPPO_01976	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_01977	1.8e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
GNFOHPPO_01978	2.05e-281	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GNFOHPPO_01979	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
GNFOHPPO_01980	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GNFOHPPO_01981	1.76e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_01982	8.4e-42	yrzR	-	-	-	-	-	-	-
GNFOHPPO_01983	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
GNFOHPPO_01984	7.94e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFOHPPO_01985	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFOHPPO_01986	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
GNFOHPPO_01987	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
GNFOHPPO_01988	2.82e-238	yrrI	-	-	S	-	-	-	AI-2E family transporter
GNFOHPPO_01989	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GNFOHPPO_01990	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GNFOHPPO_01991	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GNFOHPPO_01992	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GNFOHPPO_01993	4.67e-258	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GNFOHPPO_01994	9.44e-153	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
GNFOHPPO_01995	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
GNFOHPPO_01996	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
GNFOHPPO_01997	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
GNFOHPPO_01998	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GNFOHPPO_01999	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
GNFOHPPO_02000	7.87e-100	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
GNFOHPPO_02001	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
GNFOHPPO_02002	4.18e-154	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
GNFOHPPO_02003	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GNFOHPPO_02004	1.13e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
GNFOHPPO_02005	2.27e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GNFOHPPO_02006	1.92e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
GNFOHPPO_02007	4.76e-106	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
GNFOHPPO_02008	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
GNFOHPPO_02009	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
GNFOHPPO_02010	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
GNFOHPPO_02011	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
GNFOHPPO_02012	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
GNFOHPPO_02013	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
GNFOHPPO_02014	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
GNFOHPPO_02015	2.65e-270	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02016	5.33e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02017	1.96e-108	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GNFOHPPO_02018	2.31e-231	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
GNFOHPPO_02019	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
GNFOHPPO_02020	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_02021	1.2e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GNFOHPPO_02022	4.12e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GNFOHPPO_02023	2.05e-187	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GNFOHPPO_02024	1.76e-191	supH	-	-	S	-	-	-	hydrolase
GNFOHPPO_02026	1.94e-120	-	-	-	S	-	-	-	DinB family
GNFOHPPO_02027	4.11e-105	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
GNFOHPPO_02028	6.43e-42	-	-	-	K	-	-	-	acetyltransferase
GNFOHPPO_02029	3.86e-128	yqaC	-	-	F	-	-	-	adenylate kinase activity
GNFOHPPO_02030	1.48e-190	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
GNFOHPPO_02031	4.01e-122	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
GNFOHPPO_02032	4.39e-193	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
GNFOHPPO_02033	5.58e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GNFOHPPO_02034	8.61e-275	-	-	-	EGP	-	-	-	Transmembrane secretion effector
GNFOHPPO_02035	1.74e-35	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_02036	4.14e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
GNFOHPPO_02037	2.71e-179	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
GNFOHPPO_02038	3.07e-179	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GNFOHPPO_02040	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
GNFOHPPO_02041	1.13e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GNFOHPPO_02042	6.94e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GNFOHPPO_02043	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
GNFOHPPO_02044	4.11e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GNFOHPPO_02045	2.38e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
GNFOHPPO_02046	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GNFOHPPO_02047	8.39e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
GNFOHPPO_02048	8.04e-191	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNFOHPPO_02049	1.77e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
GNFOHPPO_02050	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
GNFOHPPO_02051	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GNFOHPPO_02052	1.28e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GNFOHPPO_02053	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GNFOHPPO_02054	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GNFOHPPO_02055	3.7e-279	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
GNFOHPPO_02056	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
GNFOHPPO_02057	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GNFOHPPO_02058	3.39e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
GNFOHPPO_02059	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GNFOHPPO_02060	2.99e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GNFOHPPO_02061	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GNFOHPPO_02062	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GNFOHPPO_02063	6.58e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
GNFOHPPO_02064	1.75e-181	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GNFOHPPO_02065	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
GNFOHPPO_02066	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GNFOHPPO_02067	3.22e-65	-	-	-	-	-	-	-	-
GNFOHPPO_02068	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
GNFOHPPO_02069	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
GNFOHPPO_02070	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GNFOHPPO_02071	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_02072	9.57e-287	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
GNFOHPPO_02073	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GNFOHPPO_02074	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
GNFOHPPO_02075	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
GNFOHPPO_02076	2.82e-185	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
GNFOHPPO_02077	2.82e-304	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
GNFOHPPO_02078	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GNFOHPPO_02079	2.6e-240	yvhJ	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02080	1.2e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
GNFOHPPO_02081	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GNFOHPPO_02082	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_02083	1.46e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02084	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GNFOHPPO_02085	2.14e-58	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
GNFOHPPO_02086	2.44e-86	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
GNFOHPPO_02087	9.09e-97	yvyF	-	-	S	-	-	-	flagellar protein
GNFOHPPO_02088	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
GNFOHPPO_02089	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
GNFOHPPO_02090	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
GNFOHPPO_02091	1.2e-208	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
GNFOHPPO_02092	1.14e-107	yviE	-	-	-	-	-	-	-
GNFOHPPO_02093	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GNFOHPPO_02094	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GNFOHPPO_02095	9.98e-154	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GNFOHPPO_02096	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GNFOHPPO_02097	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
GNFOHPPO_02098	4.35e-10	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
GNFOHPPO_02099	1.35e-89	-	-	-	-	-	-	-	-
GNFOHPPO_02100	7.96e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GNFOHPPO_02101	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GNFOHPPO_02102	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GNFOHPPO_02103	4.82e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_02104	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
GNFOHPPO_02105	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
GNFOHPPO_02106	2.48e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GNFOHPPO_02107	2.67e-308	ywoF	-	-	P	-	-	-	Right handed beta helix region
GNFOHPPO_02108	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
GNFOHPPO_02109	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
GNFOHPPO_02110	8.77e-282	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNFOHPPO_02111	3.17e-233	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GNFOHPPO_02113	2.58e-31	-	-	-	Q	-	-	-	Thioesterase domain
GNFOHPPO_02114	1.45e-298	yvkA	-	-	P	-	-	-	-transporter
GNFOHPPO_02115	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02116	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
GNFOHPPO_02117	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02118	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GNFOHPPO_02119	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GNFOHPPO_02120	2.97e-50	yvkN	-	-	-	-	-	-	-
GNFOHPPO_02121	4.87e-66	yvlA	-	-	-	-	-	-	-
GNFOHPPO_02122	7.87e-219	yvlB	-	-	S	-	-	-	Putative adhesin
GNFOHPPO_02123	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
GNFOHPPO_02124	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
GNFOHPPO_02125	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
GNFOHPPO_02126	1.27e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
GNFOHPPO_02127	1.05e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
GNFOHPPO_02128	1.9e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GNFOHPPO_02129	6.01e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GNFOHPPO_02130	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GNFOHPPO_02131	8.74e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GNFOHPPO_02132	2.33e-157	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GNFOHPPO_02133	1.07e-115	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
GNFOHPPO_02134	8.4e-177	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
GNFOHPPO_02135	6.03e-270	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GNFOHPPO_02136	1.83e-148	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GNFOHPPO_02137	3.32e-300	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GNFOHPPO_02138	3.91e-136	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
GNFOHPPO_02139	2.41e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GNFOHPPO_02140	1.38e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GNFOHPPO_02141	8e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GNFOHPPO_02142	8.12e-144	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
GNFOHPPO_02143	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
GNFOHPPO_02144	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_02145	3.91e-245	sasA	-	-	T	-	-	-	Histidine kinase
GNFOHPPO_02146	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
GNFOHPPO_02147	7.1e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
GNFOHPPO_02148	8.99e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GNFOHPPO_02149	5.15e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GNFOHPPO_02150	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GNFOHPPO_02151	8.99e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GNFOHPPO_02152	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GNFOHPPO_02153	3.23e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
GNFOHPPO_02154	6.92e-184	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
GNFOHPPO_02155	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
GNFOHPPO_02156	7.19e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFOHPPO_02157	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
GNFOHPPO_02158	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
GNFOHPPO_02159	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
GNFOHPPO_02160	1.32e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GNFOHPPO_02161	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
GNFOHPPO_02162	1.09e-274	yraM	-	-	S	-	-	-	PrpF protein
GNFOHPPO_02163	3.34e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02164	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GNFOHPPO_02165	4.69e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
GNFOHPPO_02166	9.95e-286	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
GNFOHPPO_02167	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
GNFOHPPO_02169	1.94e-47	-	-	-	-	-	-	-	-
GNFOHPPO_02170	2.06e-268	-	-	-	I	-	-	-	Pfam Lipase (class 3)
GNFOHPPO_02173	3.98e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
GNFOHPPO_02174	7.19e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
GNFOHPPO_02175	2.47e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
GNFOHPPO_02176	2.7e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFOHPPO_02177	1.02e-143	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
GNFOHPPO_02178	1.4e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
GNFOHPPO_02180	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
GNFOHPPO_02181	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
GNFOHPPO_02182	1.66e-155	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
GNFOHPPO_02183	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
GNFOHPPO_02184	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
GNFOHPPO_02185	1.01e-276	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
GNFOHPPO_02186	5.53e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
GNFOHPPO_02187	1.49e-273	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GNFOHPPO_02188	4.89e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
GNFOHPPO_02189	1.08e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
GNFOHPPO_02190	4.49e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
GNFOHPPO_02191	1.48e-249	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
GNFOHPPO_02192	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_02193	1.58e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GNFOHPPO_02194	2.19e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
GNFOHPPO_02195	3.31e-283	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
GNFOHPPO_02196	8.48e-242	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
GNFOHPPO_02197	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
GNFOHPPO_02198	2.39e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GNFOHPPO_02199	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GNFOHPPO_02200	3.1e-156	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
GNFOHPPO_02201	4.54e-284	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GNFOHPPO_02202	2.14e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GNFOHPPO_02203	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GNFOHPPO_02204	2.91e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GNFOHPPO_02205	1.95e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
GNFOHPPO_02206	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GNFOHPPO_02207	5.43e-195	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
GNFOHPPO_02208	1.79e-214	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
GNFOHPPO_02209	1.55e-149	-	-	-	S	ko:K07149	-	ko00000	Membrane
GNFOHPPO_02210	3.55e-231	yhjM	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02211	2.73e-134	-	-	-	-	-	-	-	-
GNFOHPPO_02212	9.55e-173	-	-	-	-	-	-	-	-
GNFOHPPO_02213	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_02214	5.22e-203	yvbV	-	-	EG	-	-	-	EamA-like transporter family
GNFOHPPO_02215	4.32e-200	yvbU	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02217	7.57e-243	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_02218	9.49e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
GNFOHPPO_02219	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GNFOHPPO_02221	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GNFOHPPO_02222	4.7e-237	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GNFOHPPO_02223	1.33e-275	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GNFOHPPO_02224	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GNFOHPPO_02225	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
GNFOHPPO_02226	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GNFOHPPO_02227	1.25e-305	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
GNFOHPPO_02228	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GNFOHPPO_02229	1.19e-278	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
GNFOHPPO_02230	3.49e-219	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
GNFOHPPO_02231	1.02e-298	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GNFOHPPO_02232	2.26e-191	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
GNFOHPPO_02233	2.38e-184	-	-	-	C	-	-	-	WbqC-like protein family
GNFOHPPO_02234	1.29e-161	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
GNFOHPPO_02235	6.87e-229	-	-	-	-	-	-	-	-
GNFOHPPO_02236	5.4e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GNFOHPPO_02237	1.11e-106	yvbK	-	-	K	-	-	-	acetyltransferase
GNFOHPPO_02238	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
GNFOHPPO_02239	1.32e-157	yvbI	-	-	M	-	-	-	Membrane
GNFOHPPO_02240	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
GNFOHPPO_02241	1.01e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
GNFOHPPO_02242	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GNFOHPPO_02243	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
GNFOHPPO_02244	9.31e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GNFOHPPO_02245	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
GNFOHPPO_02246	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
GNFOHPPO_02247	3.34e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GNFOHPPO_02248	2.39e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
GNFOHPPO_02249	7.98e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GNFOHPPO_02250	1.72e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
GNFOHPPO_02251	2.67e-162	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_02252	8.48e-158	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GNFOHPPO_02253	5.4e-176	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GNFOHPPO_02254	6.66e-159	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
GNFOHPPO_02255	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
GNFOHPPO_02256	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
GNFOHPPO_02257	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
GNFOHPPO_02258	5.52e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
GNFOHPPO_02259	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
GNFOHPPO_02260	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
GNFOHPPO_02261	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
GNFOHPPO_02262	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GNFOHPPO_02263	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GNFOHPPO_02266	3.41e-71	-	-	-	-	-	-	-	-
GNFOHPPO_02267	5.05e-58	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
GNFOHPPO_02268	0.000135	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_02269	5.95e-47	-	-	-	M	-	-	-	Ribonuclease
GNFOHPPO_02270	1.98e-64	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
GNFOHPPO_02271	3.94e-180	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_02272	4.65e-205	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
GNFOHPPO_02273	3.16e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GNFOHPPO_02274	5.05e-169	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
GNFOHPPO_02275	8.69e-189	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
GNFOHPPO_02276	1.47e-156	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GNFOHPPO_02277	5.8e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GNFOHPPO_02278	9e-181	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
GNFOHPPO_02279	9.08e-235	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_02280	1.44e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
GNFOHPPO_02281	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_02282	4.85e-186	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
GNFOHPPO_02283	6.16e-90	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GNFOHPPO_02284	1.85e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GNFOHPPO_02285	4.39e-209	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFOHPPO_02286	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GNFOHPPO_02287	1.74e-249	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
GNFOHPPO_02288	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
GNFOHPPO_02289	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
GNFOHPPO_02290	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GNFOHPPO_02291	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
GNFOHPPO_02292	9.54e-140	bdbD	-	-	O	-	-	-	Thioredoxin
GNFOHPPO_02293	7.48e-96	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
GNFOHPPO_02294	8.08e-192	-	-	-	S	-	-	-	Metallo-peptidase family M12
GNFOHPPO_02295	6.36e-130	yvgT	-	-	S	-	-	-	membrane
GNFOHPPO_02296	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GNFOHPPO_02297	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GNFOHPPO_02298	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GNFOHPPO_02299	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
GNFOHPPO_02300	7.97e-113	yvgO	-	-	-	-	-	-	-
GNFOHPPO_02301	1.77e-200	yvgN	-	-	S	-	-	-	reductase
GNFOHPPO_02302	5.93e-261	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
GNFOHPPO_02303	1.73e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
GNFOHPPO_02304	1.42e-219	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
GNFOHPPO_02305	1.49e-253	-	-	-	T	-	-	-	Histidine kinase
GNFOHPPO_02306	2.05e-146	yfiK	-	-	K	-	-	-	Regulator
GNFOHPPO_02307	2.84e-127	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
GNFOHPPO_02308	6.51e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
GNFOHPPO_02309	8.16e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
GNFOHPPO_02310	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
GNFOHPPO_02311	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
GNFOHPPO_02312	1.29e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
GNFOHPPO_02313	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GNFOHPPO_02314	3.67e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFOHPPO_02315	1.56e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_02316	2.76e-225	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_02317	9.78e-189	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GNFOHPPO_02318	3.98e-87	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
GNFOHPPO_02319	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
GNFOHPPO_02320	3.78e-21	-	-	-	S	-	-	-	YvrJ protein family
GNFOHPPO_02321	3.77e-133	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
GNFOHPPO_02322	1.67e-50	-	-	-	-	-	-	-	-
GNFOHPPO_02323	2.7e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_02324	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
GNFOHPPO_02325	6.55e-220	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
GNFOHPPO_02326	4.99e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_02327	1.93e-214	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GNFOHPPO_02328	1.38e-231	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_02329	9.28e-290	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GNFOHPPO_02330	4.59e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
GNFOHPPO_02331	3.37e-290	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02332	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
GNFOHPPO_02333	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GNFOHPPO_02334	3.93e-190	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GNFOHPPO_02335	5.33e-160	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
GNFOHPPO_02336	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_02337	1.02e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_02338	4.16e-258	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
GNFOHPPO_02339	1.98e-240	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
GNFOHPPO_02340	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
GNFOHPPO_02341	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
GNFOHPPO_02342	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GNFOHPPO_02343	5.92e-202	yuxN	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02344	4.63e-33	-	-	-	-	-	-	-	-
GNFOHPPO_02345	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_02346	3.17e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_02347	1.87e-305	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNFOHPPO_02348	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GNFOHPPO_02349	5.7e-199	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_02350	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
GNFOHPPO_02351	1.32e-60	-	-	-	S	-	-	-	YusW-like protein
GNFOHPPO_02352	1.29e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GNFOHPPO_02353	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
GNFOHPPO_02354	4.2e-241	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFOHPPO_02355	2.49e-177	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
GNFOHPPO_02356	1.7e-203	-	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02357	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
GNFOHPPO_02358	3.93e-91	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
GNFOHPPO_02359	4.46e-72	yusN	-	-	M	-	-	-	Coat F domain
GNFOHPPO_02360	3.2e-58	-	-	-	-	-	-	-	-
GNFOHPPO_02361	3.22e-216	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
GNFOHPPO_02362	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
GNFOHPPO_02363	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
GNFOHPPO_02364	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
GNFOHPPO_02365	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
GNFOHPPO_02366	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GNFOHPPO_02367	3.1e-55	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
GNFOHPPO_02368	3.09e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
GNFOHPPO_02369	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
GNFOHPPO_02370	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
GNFOHPPO_02371	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GNFOHPPO_02372	2.96e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
GNFOHPPO_02373	1.82e-186	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
GNFOHPPO_02374	2.54e-84	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GNFOHPPO_02375	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GNFOHPPO_02376	8.67e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
GNFOHPPO_02377	2.31e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GNFOHPPO_02378	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
GNFOHPPO_02379	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
GNFOHPPO_02380	3.07e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GNFOHPPO_02381	1.24e-103	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
GNFOHPPO_02382	2.01e-129	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
GNFOHPPO_02383	9.09e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
GNFOHPPO_02384	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
GNFOHPPO_02387	2.51e-236	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GNFOHPPO_02388	2.59e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
GNFOHPPO_02389	1.19e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
GNFOHPPO_02390	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GNFOHPPO_02391	3.08e-243	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GNFOHPPO_02392	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
GNFOHPPO_02393	4.9e-116	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GNFOHPPO_02394	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GNFOHPPO_02395	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GNFOHPPO_02396	1.65e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GNFOHPPO_02397	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
GNFOHPPO_02398	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GNFOHPPO_02399	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GNFOHPPO_02400	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GNFOHPPO_02401	1.1e-33	-	-	-	L	-	-	-	Restriction endonuclease BglII
GNFOHPPO_02402	4.48e-57	-	-	-	-	-	-	-	-
GNFOHPPO_02403	5.3e-172	-	-	-	L	-	-	-	Helicase
GNFOHPPO_02405	1.64e-176	-	2.1.1.113, 2.1.1.72	-	L	ko:K00571,ko:K00590	-	ko00000,ko01000,ko02048	N-4 methylation of cytosine
GNFOHPPO_02406	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
GNFOHPPO_02407	2.91e-256	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
GNFOHPPO_02408	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
GNFOHPPO_02409	7.03e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
GNFOHPPO_02410	4.21e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
GNFOHPPO_02411	1.17e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
GNFOHPPO_02412	7.35e-228	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GNFOHPPO_02413	1.35e-163	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
GNFOHPPO_02414	8.25e-210	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
GNFOHPPO_02415	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
GNFOHPPO_02416	1.04e-188	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
GNFOHPPO_02417	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_02418	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
GNFOHPPO_02419	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
GNFOHPPO_02420	4.28e-196	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
GNFOHPPO_02422	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
GNFOHPPO_02423	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
GNFOHPPO_02424	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_02425	5.03e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNFOHPPO_02426	1.38e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
GNFOHPPO_02427	2.8e-277	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GNFOHPPO_02428	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
GNFOHPPO_02429	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GNFOHPPO_02430	4.92e-167	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_02431	2.81e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
GNFOHPPO_02432	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
GNFOHPPO_02433	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GNFOHPPO_02434	9.82e-165	yebC	-	-	M	-	-	-	Membrane
GNFOHPPO_02436	8.54e-119	yebE	-	-	S	-	-	-	UPF0316 protein
GNFOHPPO_02437	6.56e-40	yebG	-	-	S	-	-	-	NETI protein
GNFOHPPO_02438	7.63e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GNFOHPPO_02439	1.07e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GNFOHPPO_02440	6.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GNFOHPPO_02441	8.68e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
GNFOHPPO_02442	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFOHPPO_02443	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFOHPPO_02444	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFOHPPO_02445	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GNFOHPPO_02446	5.33e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
GNFOHPPO_02447	7.3e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GNFOHPPO_02448	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
GNFOHPPO_02449	9.84e-299	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
GNFOHPPO_02450	4.18e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
GNFOHPPO_02451	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
GNFOHPPO_02452	7.32e-248	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
GNFOHPPO_02453	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02454	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
GNFOHPPO_02455	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GNFOHPPO_02456	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GNFOHPPO_02457	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GNFOHPPO_02458	2.74e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
GNFOHPPO_02459	2.55e-248	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
GNFOHPPO_02460	1.68e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
GNFOHPPO_02461	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GNFOHPPO_02462	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GNFOHPPO_02463	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GNFOHPPO_02464	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GNFOHPPO_02465	3.03e-195	yerO	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02466	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNFOHPPO_02467	2.02e-215	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GNFOHPPO_02468	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GNFOHPPO_02469	5.81e-250	-	-	-	L	-	-	-	AAA ATPase domain
GNFOHPPO_02470	1.68e-140	-	-	-	L	-	-	-	AAA domain
GNFOHPPO_02471	1.39e-85	-	-	-	-	-	-	-	-
GNFOHPPO_02473	6.66e-39	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
GNFOHPPO_02475	4.08e-107	-	-	-	S	-	-	-	Protein of unknown function, DUF600
GNFOHPPO_02476	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
GNFOHPPO_02477	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
GNFOHPPO_02479	4.94e-137	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
GNFOHPPO_02480	4.61e-61	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
GNFOHPPO_02481	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
GNFOHPPO_02482	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
GNFOHPPO_02483	5.67e-123	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GNFOHPPO_02484	5.92e-05	-	-	-	-	-	-	-	-
GNFOHPPO_02485	8.99e-157	yetF	-	-	S	-	-	-	membrane
GNFOHPPO_02486	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
GNFOHPPO_02487	1.32e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFOHPPO_02488	6.55e-199	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GNFOHPPO_02489	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
GNFOHPPO_02490	1.82e-73	-	-	-	H	-	-	-	riboflavin kinase activity
GNFOHPPO_02491	2.19e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GNFOHPPO_02492	4.9e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_02493	1.04e-265	yetM	-	-	CH	-	-	-	FAD binding domain
GNFOHPPO_02494	2.38e-252	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
GNFOHPPO_02495	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
GNFOHPPO_02497	5.83e-67	-	-	-	K	-	-	-	Winged helix DNA-binding domain
GNFOHPPO_02498	6.49e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GNFOHPPO_02499	3.76e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
GNFOHPPO_02500	3.36e-130	-	-	-	S	-	-	-	protein homooligomerization
GNFOHPPO_02501	1.98e-167	-	-	-	-	-	-	-	-
GNFOHPPO_02502	1.31e-245	-	-	-	S	-	-	-	ATP diphosphatase activity
GNFOHPPO_02503	0.0	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GNFOHPPO_02504	5.49e-196	-	-	-	C	-	-	-	Nitroreductase family
GNFOHPPO_02505	2.13e-149	-	-	-	S	-	-	-	CAAX protease self-immunity
GNFOHPPO_02506	2.68e-187	-	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	methyltransferase
GNFOHPPO_02508	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
GNFOHPPO_02509	1.77e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
GNFOHPPO_02510	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
GNFOHPPO_02511	6.89e-232	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
GNFOHPPO_02512	1.78e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
GNFOHPPO_02513	1.71e-239	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
GNFOHPPO_02514	2.7e-278	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02515	4.33e-315	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
GNFOHPPO_02516	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GNFOHPPO_02517	5.01e-163	yfmS	-	-	NT	-	-	-	chemotaxis protein
GNFOHPPO_02518	2.1e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_02519	3.6e-267	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
GNFOHPPO_02520	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GNFOHPPO_02521	1.76e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
GNFOHPPO_02522	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
GNFOHPPO_02523	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GNFOHPPO_02524	6.48e-267	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
GNFOHPPO_02525	3.29e-83	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
GNFOHPPO_02526	8.49e-242	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
GNFOHPPO_02527	4.44e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
GNFOHPPO_02528	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
GNFOHPPO_02529	5.58e-309	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
GNFOHPPO_02530	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GNFOHPPO_02538	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
GNFOHPPO_02539	1.38e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GNFOHPPO_02540	1.96e-226	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
GNFOHPPO_02541	2.01e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
GNFOHPPO_02542	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
GNFOHPPO_02543	2.03e-277	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GNFOHPPO_02544	9.63e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GNFOHPPO_02545	5.92e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02546	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
GNFOHPPO_02547	1.98e-26	yflI	-	-	-	-	-	-	-
GNFOHPPO_02548	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
GNFOHPPO_02549	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
GNFOHPPO_02550	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GNFOHPPO_02551	7.03e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
GNFOHPPO_02552	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
GNFOHPPO_02553	4.03e-82	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
GNFOHPPO_02554	5.85e-104	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GNFOHPPO_02555	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
GNFOHPPO_02556	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
GNFOHPPO_02557	1.57e-313	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_02558	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
GNFOHPPO_02559	1.18e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
GNFOHPPO_02560	2.93e-158	frp	-	-	C	-	-	-	nitroreductase
GNFOHPPO_02561	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
GNFOHPPO_02562	1.55e-255	yibE	-	-	S	-	-	-	YibE/F-like protein
GNFOHPPO_02564	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
GNFOHPPO_02565	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
GNFOHPPO_02566	9.13e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GNFOHPPO_02567	6.12e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GNFOHPPO_02568	2.04e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GNFOHPPO_02569	6.98e-252	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02570	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
GNFOHPPO_02571	1.69e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNFOHPPO_02572	1.29e-70	yfkI	-	-	S	-	-	-	gas vesicle protein
GNFOHPPO_02573	1.37e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GNFOHPPO_02574	6.71e-12	-	-	-	-	-	-	-	-
GNFOHPPO_02575	7.18e-279	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02576	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
GNFOHPPO_02577	8.04e-186	yfkD	-	-	S	-	-	-	YfkD-like protein
GNFOHPPO_02578	5.2e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
GNFOHPPO_02579	2.4e-281	yfkA	-	-	S	-	-	-	YfkB-like domain
GNFOHPPO_02580	7.99e-37	yfjT	-	-	-	-	-	-	-
GNFOHPPO_02581	5.1e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
GNFOHPPO_02582	4.82e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GNFOHPPO_02584	9.11e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
GNFOHPPO_02585	1.04e-209	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GNFOHPPO_02586	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GNFOHPPO_02587	8.78e-67	-	-	-	S	-	-	-	YfzA-like protein
GNFOHPPO_02588	2.97e-245	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNFOHPPO_02589	4.85e-114	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
GNFOHPPO_02590	3.21e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GNFOHPPO_02591	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GNFOHPPO_02592	6.85e-275	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GNFOHPPO_02593	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GNFOHPPO_02594	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
GNFOHPPO_02595	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
GNFOHPPO_02596	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GNFOHPPO_02597	4.47e-178	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
GNFOHPPO_02598	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_02599	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GNFOHPPO_02600	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
GNFOHPPO_02601	1.36e-82	yfiD3	-	-	S	-	-	-	DoxX
GNFOHPPO_02602	1.16e-205	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
GNFOHPPO_02603	1.53e-216	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GNFOHPPO_02604	5.62e-126	padR	-	-	K	-	-	-	transcriptional
GNFOHPPO_02605	4.22e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GNFOHPPO_02606	3.42e-239	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GNFOHPPO_02607	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
GNFOHPPO_02608	2.87e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
GNFOHPPO_02609	2.8e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
GNFOHPPO_02610	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
GNFOHPPO_02611	3.95e-108	yfiV	-	-	K	-	-	-	transcriptional
GNFOHPPO_02612	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GNFOHPPO_02613	7.89e-213	yfhB	-	-	S	-	-	-	PhzF family
GNFOHPPO_02614	8.22e-138	yfhC	-	-	C	-	-	-	nitroreductase
GNFOHPPO_02615	1.47e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
GNFOHPPO_02617	2.35e-212	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
GNFOHPPO_02618	4.28e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
GNFOHPPO_02619	2.66e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
GNFOHPPO_02620	2.86e-268	yfhI	-	-	EGP	-	-	-	-transporter
GNFOHPPO_02622	3.48e-216	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
GNFOHPPO_02623	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
GNFOHPPO_02624	9.45e-121	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
GNFOHPPO_02625	1.48e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
GNFOHPPO_02626	2.37e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase family
GNFOHPPO_02627	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
GNFOHPPO_02628	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
GNFOHPPO_02629	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
GNFOHPPO_02630	3.42e-170	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFOHPPO_02631	2.12e-56	-	-	-	E	-	-	-	Zn peptidase
GNFOHPPO_02632	1.01e-42	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFOHPPO_02633	1.61e-24	-	-	-	-	-	-	-	-
GNFOHPPO_02634	3.79e-39	-	-	-	-	-	-	-	-
GNFOHPPO_02638	6.17e-107	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
GNFOHPPO_02641	1.13e-65	-	-	-	L	-	-	-	DnaD domain protein
GNFOHPPO_02642	1.5e-19	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
GNFOHPPO_02643	4.27e-211	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
GNFOHPPO_02644	6.45e-34	-	-	-	-	-	-	-	-
GNFOHPPO_02647	4.77e-38	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
GNFOHPPO_02648	2.49e-105	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GNFOHPPO_02649	3.29e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
GNFOHPPO_02650	2.88e-26	-	-	-	N	-	-	-	PFAM YcfA family protein
GNFOHPPO_02654	6e-43	-	-	-	V	-	-	-	HNH nucleases
GNFOHPPO_02655	6.2e-63	-	-	-	L	-	-	-	Phage terminase, small subunit
GNFOHPPO_02656	0.0	-	-	-	S	-	-	-	Terminase
GNFOHPPO_02657	4.35e-86	-	-	-	S	-	-	-	Phage portal protein
GNFOHPPO_02658	7.72e-88	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
GNFOHPPO_02659	1.04e-146	-	-	-	S	-	-	-	Phage capsid family
GNFOHPPO_02666	1.1e-66	-	-	-	S	-	-	-	Phage-related minor tail protein
GNFOHPPO_02667	8.28e-21	-	-	-	S	-	-	-	Phage tail protein
GNFOHPPO_02668	1.74e-14	-	-	-	M	-	-	-	Prophage endopeptidase tail
GNFOHPPO_02669	3.17e-111	-	-	-	S	-	-	-	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GNFOHPPO_02670	2.33e-129	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GNFOHPPO_02671	7.23e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
GNFOHPPO_02674	4.67e-29	bhlA	-	-	S	-	-	-	BhlA holin family
GNFOHPPO_02675	2.82e-33	xhlB	-	-	S	-	-	-	SPP1 phage holin
GNFOHPPO_02676	8.91e-86	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
GNFOHPPO_02677	1.75e-83	-	-	-	-	-	-	-	-
GNFOHPPO_02678	6.56e-52	-	-	-	-	-	-	-	-
GNFOHPPO_02679	3.07e-131	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
GNFOHPPO_02680	9.18e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
GNFOHPPO_02681	2.54e-50	yfhS	-	-	-	-	-	-	-
GNFOHPPO_02682	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_02683	4.77e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
GNFOHPPO_02684	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
GNFOHPPO_02685	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
GNFOHPPO_02686	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
GNFOHPPO_02687	5.48e-239	ygaE	-	-	S	-	-	-	Membrane
GNFOHPPO_02688	6.86e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
GNFOHPPO_02689	1.39e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
GNFOHPPO_02690	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
GNFOHPPO_02691	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
GNFOHPPO_02692	1.12e-212	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
GNFOHPPO_02693	5.71e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNFOHPPO_02694	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
GNFOHPPO_02696	5.46e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
GNFOHPPO_02698	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_02699	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
GNFOHPPO_02700	3.52e-26	ywdA	-	-	-	-	-	-	-
GNFOHPPO_02701	8.33e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GNFOHPPO_02702	1.6e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
GNFOHPPO_02703	8.16e-115	ywdD	-	-	-	-	-	-	-
GNFOHPPO_02705	6.93e-194	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
GNFOHPPO_02706	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GNFOHPPO_02707	1.51e-60	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
GNFOHPPO_02708	3.96e-293	ywdJ	-	-	F	-	-	-	Xanthine uracil
GNFOHPPO_02709	6.23e-76	ywdK	-	-	S	-	-	-	small membrane protein
GNFOHPPO_02710	1.49e-89	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GNFOHPPO_02711	1.29e-183	spsA	-	-	M	-	-	-	Spore Coat
GNFOHPPO_02712	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
GNFOHPPO_02713	3.06e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
GNFOHPPO_02714	4.04e-207	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
GNFOHPPO_02715	5.82e-273	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
GNFOHPPO_02716	4.29e-173	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
GNFOHPPO_02717	1.25e-236	spsG	-	-	M	-	-	-	Spore Coat
GNFOHPPO_02718	6.9e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GNFOHPPO_02719	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GNFOHPPO_02720	3.34e-208	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GNFOHPPO_02721	3.29e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
GNFOHPPO_02722	6.37e-77	-	-	-	-	-	-	-	-
GNFOHPPO_02723	3.67e-313	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
GNFOHPPO_02724	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
GNFOHPPO_02725	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
GNFOHPPO_02726	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GNFOHPPO_02727	2.43e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
GNFOHPPO_02728	4.24e-288	ywfA	-	-	EGP	-	-	-	-transporter
GNFOHPPO_02729	4.68e-145	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GNFOHPPO_02730	2.81e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GNFOHPPO_02731	8.05e-181	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_02732	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GNFOHPPO_02733	1.16e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
GNFOHPPO_02734	2.58e-296	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
GNFOHPPO_02735	2.94e-181	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_02736	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
GNFOHPPO_02737	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
GNFOHPPO_02738	1.69e-213	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GNFOHPPO_02739	3.89e-211	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_02740	9.14e-204	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GNFOHPPO_02742	2e-239	-	-	-	-	-	-	-	-
GNFOHPPO_02745	1.03e-215	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
GNFOHPPO_02746	3.46e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_02747	5.36e-120	-	-	-	S	-	-	-	membrane
GNFOHPPO_02748	1.08e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
GNFOHPPO_02749	3.52e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
GNFOHPPO_02750	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
GNFOHPPO_02751	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
GNFOHPPO_02752	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
GNFOHPPO_02753	5.69e-315	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
GNFOHPPO_02754	3.42e-92	ywhA	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02755	3.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
GNFOHPPO_02756	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
GNFOHPPO_02757	3.32e-124	ywhD	-	-	S	-	-	-	YwhD family
GNFOHPPO_02758	3.66e-107	-	-	-	-	-	-	-	-
GNFOHPPO_02759	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GNFOHPPO_02760	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GNFOHPPO_02761	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
GNFOHPPO_02764	4.89e-100	-	-	-	CP	-	-	-	Membrane
GNFOHPPO_02766	2.38e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
GNFOHPPO_02767	2.41e-45	-	-	-	-	-	-	-	-
GNFOHPPO_02768	9.15e-41	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
GNFOHPPO_02770	1.16e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
GNFOHPPO_02771	5.21e-295	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
GNFOHPPO_02772	3.67e-310	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
GNFOHPPO_02774	1.14e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02775	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GNFOHPPO_02776	2.12e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
GNFOHPPO_02777	1.33e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
GNFOHPPO_02778	5.06e-177	ywiC	-	-	S	-	-	-	YwiC-like protein
GNFOHPPO_02779	1.01e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
GNFOHPPO_02780	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GNFOHPPO_02781	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
GNFOHPPO_02782	4.61e-126	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
GNFOHPPO_02783	2.93e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
GNFOHPPO_02784	4.29e-136	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GNFOHPPO_02785	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GNFOHPPO_02786	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GNFOHPPO_02787	1.13e-58	ywjC	-	-	-	-	-	-	-
GNFOHPPO_02788	1.83e-231	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GNFOHPPO_02789	2.97e-286	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GNFOHPPO_02790	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
GNFOHPPO_02791	6.53e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GNFOHPPO_02792	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GNFOHPPO_02793	8.11e-121	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
GNFOHPPO_02794	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
GNFOHPPO_02795	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
GNFOHPPO_02796	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GNFOHPPO_02797	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GNFOHPPO_02798	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
GNFOHPPO_02799	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GNFOHPPO_02800	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
GNFOHPPO_02801	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GNFOHPPO_02802	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
GNFOHPPO_02803	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GNFOHPPO_02804	1.48e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GNFOHPPO_02805	9.07e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFOHPPO_02806	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GNFOHPPO_02807	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GNFOHPPO_02809	2.08e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
GNFOHPPO_02810	6.57e-153	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
GNFOHPPO_02811	5.15e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
GNFOHPPO_02812	1.53e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GNFOHPPO_02813	1.17e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
GNFOHPPO_02814	8.46e-101	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNFOHPPO_02815	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
GNFOHPPO_02816	1.5e-124	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
GNFOHPPO_02817	1.78e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GNFOHPPO_02818	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GNFOHPPO_02819	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
GNFOHPPO_02820	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GNFOHPPO_02821	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GNFOHPPO_02822	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GNFOHPPO_02823	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GNFOHPPO_02824	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GNFOHPPO_02825	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GNFOHPPO_02826	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GNFOHPPO_02827	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GNFOHPPO_02828	1.76e-118	ywmA	-	-	-	-	-	-	-
GNFOHPPO_02829	1.3e-44	ywzB	-	-	S	-	-	-	membrane
GNFOHPPO_02830	5.64e-173	ywmB	-	-	S	-	-	-	TATA-box binding
GNFOHPPO_02831	2.87e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GNFOHPPO_02832	1.16e-241	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
GNFOHPPO_02833	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
GNFOHPPO_02834	7.14e-157	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
GNFOHPPO_02836	1.5e-185	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GNFOHPPO_02837	1.31e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GNFOHPPO_02838	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
GNFOHPPO_02839	1.05e-107	ywmF	-	-	S	-	-	-	Peptidase M50
GNFOHPPO_02840	2.51e-18	csbD	-	-	K	-	-	-	CsbD-like
GNFOHPPO_02841	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
GNFOHPPO_02842	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
GNFOHPPO_02843	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GNFOHPPO_02844	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02845	3.07e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
GNFOHPPO_02846	1.97e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
GNFOHPPO_02847	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GNFOHPPO_02848	1.48e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
GNFOHPPO_02850	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
GNFOHPPO_02851	1.31e-188	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
GNFOHPPO_02852	4.67e-95	ywnJ	-	-	S	-	-	-	VanZ like family
GNFOHPPO_02853	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
GNFOHPPO_02854	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GNFOHPPO_02855	1.51e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
GNFOHPPO_02856	2.67e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
GNFOHPPO_02857	1.13e-132	yjgF	-	-	Q	-	-	-	Isochorismatase family
GNFOHPPO_02858	5.42e-310	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
GNFOHPPO_02859	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
GNFOHPPO_02860	1.37e-270	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02861	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
GNFOHPPO_02862	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
GNFOHPPO_02863	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
GNFOHPPO_02864	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
GNFOHPPO_02865	9.37e-188	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
GNFOHPPO_02866	1.63e-258	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
GNFOHPPO_02867	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GNFOHPPO_02868	7.6e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GNFOHPPO_02869	9.16e-91	ywpF	-	-	S	-	-	-	YwpF-like protein
GNFOHPPO_02870	4.49e-82	ywpG	-	-	-	-	-	-	-
GNFOHPPO_02871	5.51e-71	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
GNFOHPPO_02872	4.82e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
GNFOHPPO_02873	2.15e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
GNFOHPPO_02874	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
GNFOHPPO_02875	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
GNFOHPPO_02876	1.74e-21	-	-	-	-	-	-	-	-
GNFOHPPO_02877	3.53e-152	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
GNFOHPPO_02878	7.7e-158	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
GNFOHPPO_02879	5.24e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
GNFOHPPO_02880	1.76e-313	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GNFOHPPO_02881	1.46e-192	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
GNFOHPPO_02884	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
GNFOHPPO_02885	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
GNFOHPPO_02886	2.05e-66	-	-	-	-	-	-	-	-
GNFOHPPO_02887	6.13e-45	-	-	-	M	-	-	-	COG3209 Rhs family protein
GNFOHPPO_02888	5.96e-119	-	-	-	-	-	-	-	-
GNFOHPPO_02889	1.07e-22	-	-	-	-	-	-	-	-
GNFOHPPO_02890	5.42e-64	-	-	-	-	-	-	-	-
GNFOHPPO_02892	3.76e-123	-	-	-	-	-	-	-	-
GNFOHPPO_02893	9.45e-124	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GNFOHPPO_02894	2.47e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
GNFOHPPO_02895	1.2e-131	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
GNFOHPPO_02896	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
GNFOHPPO_02897	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
GNFOHPPO_02899	2.83e-144	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GNFOHPPO_02900	1.75e-25	-	-	-	-	-	-	-	-
GNFOHPPO_02901	2.76e-271	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
GNFOHPPO_02902	4.32e-184	cotB	-	-	-	ko:K06325	-	ko00000	-
GNFOHPPO_02903	3.43e-163	ywrJ	-	-	-	-	-	-	-
GNFOHPPO_02904	1.27e-307	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GNFOHPPO_02905	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
GNFOHPPO_02906	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GNFOHPPO_02907	3.31e-190	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
GNFOHPPO_02908	2.13e-124	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
GNFOHPPO_02909	3.54e-117	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
GNFOHPPO_02910	6.93e-208	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
GNFOHPPO_02911	1.54e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GNFOHPPO_02912	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GNFOHPPO_02913	4.8e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GNFOHPPO_02914	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GNFOHPPO_02915	4.28e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
GNFOHPPO_02916	1.69e-258	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
GNFOHPPO_02917	4.4e-247	-	-	-	E	-	-	-	Spore germination protein
GNFOHPPO_02918	8.89e-242	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
GNFOHPPO_02919	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
GNFOHPPO_02920	5.2e-49	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
GNFOHPPO_02921	2.7e-278	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GNFOHPPO_02922	4.04e-29	ywtC	-	-	-	-	-	-	-
GNFOHPPO_02923	7.5e-302	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GNFOHPPO_02924	7.85e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
GNFOHPPO_02925	2.15e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
GNFOHPPO_02926	1.39e-230	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_02927	3.45e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GNFOHPPO_02928	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
GNFOHPPO_02929	8.96e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
GNFOHPPO_02930	1.28e-253	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
GNFOHPPO_02931	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
GNFOHPPO_02932	3.72e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GNFOHPPO_02933	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GNFOHPPO_02934	2.6e-279	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GNFOHPPO_02935	3.69e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GNFOHPPO_02936	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
GNFOHPPO_02937	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
GNFOHPPO_02938	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GNFOHPPO_02939	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
GNFOHPPO_02940	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GNFOHPPO_02941	7.57e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GNFOHPPO_02942	2.67e-272	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GNFOHPPO_02944	3.91e-27	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
GNFOHPPO_02945	3.81e-95	-	-	-	-	-	-	-	-
GNFOHPPO_02947	9.13e-210	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GNFOHPPO_02948	3.87e-237	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GNFOHPPO_02949	5.21e-313	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
GNFOHPPO_02950	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GNFOHPPO_02951	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
GNFOHPPO_02952	7.55e-206	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
GNFOHPPO_02953	2.8e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
GNFOHPPO_02954	9.54e-265	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_02955	2.37e-216	bsn	-	-	L	-	-	-	Ribonuclease
GNFOHPPO_02956	1.07e-302	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GNFOHPPO_02957	5.47e-298	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GNFOHPPO_02958	4.1e-272	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_02960	1.57e-06	-	-	-	-	-	-	-	-
GNFOHPPO_02962	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
GNFOHPPO_02963	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GNFOHPPO_02964	5.25e-81	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
GNFOHPPO_02965	6.03e-216	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
GNFOHPPO_02966	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GNFOHPPO_02967	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GNFOHPPO_02968	4.76e-168	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
GNFOHPPO_02969	3.92e-249	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
GNFOHPPO_02970	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GNFOHPPO_02971	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02972	5.39e-96	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
GNFOHPPO_02973	4.31e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GNFOHPPO_02974	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
GNFOHPPO_02975	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
GNFOHPPO_02976	1.43e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GNFOHPPO_02977	9.76e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GNFOHPPO_02978	7.89e-216	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GNFOHPPO_02979	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
GNFOHPPO_02980	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
GNFOHPPO_02981	3.29e-73	yuzD	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_02982	2.08e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GNFOHPPO_02983	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
GNFOHPPO_02984	3e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GNFOHPPO_02985	5.54e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GNFOHPPO_02986	3.95e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
GNFOHPPO_02987	8.64e-176	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_02988	3.41e-121	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
GNFOHPPO_02990	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
GNFOHPPO_02992	1.18e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GNFOHPPO_02993	4.86e-92	-	-	-	CP	-	-	-	Membrane
GNFOHPPO_02994	5.68e-40	-	-	-	-	-	-	-	-
GNFOHPPO_02995	4.7e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GNFOHPPO_02997	1.03e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
GNFOHPPO_02998	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GNFOHPPO_02999	2.45e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
GNFOHPPO_03000	9.86e-153	yuiC	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03001	1.43e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
GNFOHPPO_03002	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GNFOHPPO_03003	1.35e-274	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
GNFOHPPO_03004	7.52e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
GNFOHPPO_03005	6.52e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
GNFOHPPO_03006	1.53e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
GNFOHPPO_03007	1.28e-173	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_03008	3.9e-286	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
GNFOHPPO_03009	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
GNFOHPPO_03010	2.37e-221	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
GNFOHPPO_03011	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03012	4.01e-48	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
GNFOHPPO_03013	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
GNFOHPPO_03014	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
GNFOHPPO_03015	5.19e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
GNFOHPPO_03016	2.36e-61	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
GNFOHPPO_03017	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
GNFOHPPO_03018	3.77e-274	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
GNFOHPPO_03019	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GNFOHPPO_03020	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
GNFOHPPO_03021	8.01e-102	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
GNFOHPPO_03022	4.81e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GNFOHPPO_03023	4.5e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
GNFOHPPO_03024	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
GNFOHPPO_03025	1.88e-238	yueF	-	-	S	-	-	-	transporter activity
GNFOHPPO_03026	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
GNFOHPPO_03027	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
GNFOHPPO_03028	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GNFOHPPO_03029	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
GNFOHPPO_03030	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GNFOHPPO_03031	6.86e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
GNFOHPPO_03032	6.01e-67	yuzC	-	-	-	-	-	-	-
GNFOHPPO_03033	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
GNFOHPPO_03034	2.49e-196	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
GNFOHPPO_03036	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_03037	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_03038	8.4e-85	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
GNFOHPPO_03039	4.2e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
GNFOHPPO_03040	1.91e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GNFOHPPO_03041	6.08e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GNFOHPPO_03042	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GNFOHPPO_03043	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GNFOHPPO_03044	2.2e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GNFOHPPO_03045	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GNFOHPPO_03047	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GNFOHPPO_03048	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GNFOHPPO_03049	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03050	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
GNFOHPPO_03051	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
GNFOHPPO_03052	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
GNFOHPPO_03053	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
GNFOHPPO_03054	2.62e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03055	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
GNFOHPPO_03056	2.25e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
GNFOHPPO_03057	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
GNFOHPPO_03058	6.88e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
GNFOHPPO_03059	4.27e-291	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_03060	9.52e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GNFOHPPO_03061	4.25e-55	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
GNFOHPPO_03062	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
GNFOHPPO_03063	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_03064	1.38e-265	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
GNFOHPPO_03065	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
GNFOHPPO_03066	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
GNFOHPPO_03067	4.92e-288	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
GNFOHPPO_03068	3.92e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
GNFOHPPO_03069	4.59e-51	ycaC	-	-	Q	-	-	-	Isochorismatase family
GNFOHPPO_03070	1.17e-51	ycaC	-	-	Q	-	-	-	Isochorismatase family
GNFOHPPO_03071	3.24e-132	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
GNFOHPPO_03073	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GNFOHPPO_03075	2.09e-95	yugN	-	-	S	-	-	-	YugN-like family
GNFOHPPO_03076	4.84e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
GNFOHPPO_03077	4.23e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
GNFOHPPO_03078	1.24e-22	-	-	-	-	-	-	-	-
GNFOHPPO_03079	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
GNFOHPPO_03080	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
GNFOHPPO_03081	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
GNFOHPPO_03082	7.17e-99	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
GNFOHPPO_03083	1.65e-241	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GNFOHPPO_03084	1.61e-55	-	-	-	-	-	-	-	-
GNFOHPPO_03085	2.22e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
GNFOHPPO_03086	7.88e-298	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
GNFOHPPO_03087	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
GNFOHPPO_03088	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
GNFOHPPO_03089	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
GNFOHPPO_03090	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
GNFOHPPO_03091	1.35e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
GNFOHPPO_03092	6.02e-252	yubA	-	-	S	-	-	-	transporter activity
GNFOHPPO_03093	9.32e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GNFOHPPO_03095	1.52e-68	yjcN	-	-	-	-	-	-	-
GNFOHPPO_03096	1.92e-159	-	-	-	G	-	-	-	Cupin
GNFOHPPO_03097	4.36e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GNFOHPPO_03098	1.62e-194	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GNFOHPPO_03099	6.13e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
GNFOHPPO_03100	2.03e-122	yuaB	-	-	-	-	-	-	-
GNFOHPPO_03101	3.51e-125	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
GNFOHPPO_03102	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GNFOHPPO_03103	2.47e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
GNFOHPPO_03104	6.79e-141	-	-	-	S	-	-	-	MOSC domain
GNFOHPPO_03105	1.08e-106	yuaE	-	-	S	-	-	-	DinB superfamily
GNFOHPPO_03106	1.96e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
GNFOHPPO_03107	1.52e-270	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
GNFOHPPO_03108	1.46e-126	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
GNFOHPPO_03110	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
GNFOHPPO_03111	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
GNFOHPPO_03112	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GNFOHPPO_03113	7.25e-202	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GNFOHPPO_03114	2.4e-232	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GNFOHPPO_03115	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GNFOHPPO_03116	2.9e-226	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GNFOHPPO_03117	1.1e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
GNFOHPPO_03118	5.4e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GNFOHPPO_03119	3.09e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
GNFOHPPO_03120	1.03e-201	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GNFOHPPO_03121	4.9e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GNFOHPPO_03122	9.37e-159	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_03123	7.95e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_03124	6.34e-180	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03125	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
GNFOHPPO_03126	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
GNFOHPPO_03127	4.82e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
GNFOHPPO_03129	6.65e-21	-	-	-	-	-	-	-	-
GNFOHPPO_03130	5.09e-35	yxeD	-	-	-	-	-	-	-
GNFOHPPO_03131	2.39e-41	yxeE	-	-	-	-	-	-	-
GNFOHPPO_03134	2.32e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
GNFOHPPO_03135	1e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GNFOHPPO_03136	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GNFOHPPO_03137	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GNFOHPPO_03138	3.85e-297	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
GNFOHPPO_03139	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GNFOHPPO_03140	3.38e-225	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GNFOHPPO_03141	3.18e-299	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
GNFOHPPO_03142	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GNFOHPPO_03143	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
GNFOHPPO_03144	1.42e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GNFOHPPO_03145	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
GNFOHPPO_03146	8.02e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GNFOHPPO_03147	0.0	-	-	-	L	-	-	-	HKD family nuclease
GNFOHPPO_03148	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_03149	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GNFOHPPO_03150	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
GNFOHPPO_03151	4.18e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
GNFOHPPO_03152	3.29e-258	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
GNFOHPPO_03153	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
GNFOHPPO_03154	5.63e-42	-	-	-	-	-	-	-	-
GNFOHPPO_03158	2.56e-11	yxiJ	-	-	S	-	-	-	YxiJ-like protein
GNFOHPPO_03159	4.6e-28	-	-	-	-	-	-	-	-
GNFOHPPO_03161	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GNFOHPPO_03162	2.12e-281	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
GNFOHPPO_03163	4.85e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
GNFOHPPO_03164	3.44e-186	bglS	-	-	M	-	-	-	licheninase activity
GNFOHPPO_03165	6.68e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
GNFOHPPO_03166	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
GNFOHPPO_03167	2.68e-67	yxiS	-	-	-	-	-	-	-
GNFOHPPO_03168	1.04e-116	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
GNFOHPPO_03169	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GNFOHPPO_03170	8.18e-210	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
GNFOHPPO_03171	1.14e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
GNFOHPPO_03172	2.28e-97	yxjI	-	-	S	-	-	-	LURP-one-related
GNFOHPPO_03175	3.3e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GNFOHPPO_03176	3.24e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GNFOHPPO_03177	7.67e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
GNFOHPPO_03178	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GNFOHPPO_03179	2.45e-213	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
GNFOHPPO_03180	1.76e-259	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_03181	1.99e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
GNFOHPPO_03182	6.74e-289	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
GNFOHPPO_03183	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
GNFOHPPO_03184	2.16e-239	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
GNFOHPPO_03185	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
GNFOHPPO_03186	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
GNFOHPPO_03187	1.52e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GNFOHPPO_03188	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
GNFOHPPO_03189	7.89e-246	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
GNFOHPPO_03190	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
GNFOHPPO_03191	6.47e-268	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
GNFOHPPO_03192	3.72e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GNFOHPPO_03193	3.62e-213	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
GNFOHPPO_03194	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GNFOHPPO_03195	6.01e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GNFOHPPO_03196	2.65e-64	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_03197	3.38e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_03198	4.43e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GNFOHPPO_03199	6.41e-77	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
GNFOHPPO_03200	9.23e-214	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
GNFOHPPO_03201	4.83e-231	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_03202	1.15e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFOHPPO_03203	5.36e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GNFOHPPO_03204	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
GNFOHPPO_03205	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
GNFOHPPO_03206	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GNFOHPPO_03207	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GNFOHPPO_03208	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GNFOHPPO_03209	3.31e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
GNFOHPPO_03210	1.53e-289	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GNFOHPPO_03211	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03212	2.56e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
GNFOHPPO_03213	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03214	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GNFOHPPO_03215	1.07e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
GNFOHPPO_03216	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
GNFOHPPO_03217	6.3e-209	gspA	-	-	M	-	-	-	General stress
GNFOHPPO_03218	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
GNFOHPPO_03219	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GNFOHPPO_03220	4.32e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
GNFOHPPO_03221	1.53e-286	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
GNFOHPPO_03222	1.17e-217	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
GNFOHPPO_03223	4.15e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
GNFOHPPO_03224	1.01e-154	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
GNFOHPPO_03225	3.01e-185	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
GNFOHPPO_03226	5.91e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GNFOHPPO_03227	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GNFOHPPO_03228	1.19e-57	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
GNFOHPPO_03229	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
GNFOHPPO_03230	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GNFOHPPO_03231	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GNFOHPPO_03232	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GNFOHPPO_03233	2.43e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GNFOHPPO_03234	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
GNFOHPPO_03235	1.57e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
GNFOHPPO_03236	5.77e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
GNFOHPPO_03237	4.33e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
GNFOHPPO_03238	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
GNFOHPPO_03239	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
GNFOHPPO_03240	9.6e-212	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
GNFOHPPO_03241	7.51e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GNFOHPPO_03242	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
GNFOHPPO_03243	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
GNFOHPPO_03244	1.96e-225	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GNFOHPPO_03245	9.53e-213	ytlQ	-	-	-	-	-	-	-
GNFOHPPO_03246	1.1e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GNFOHPPO_03247	2.38e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GNFOHPPO_03248	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
GNFOHPPO_03249	4.07e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GNFOHPPO_03250	1.29e-278	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
GNFOHPPO_03251	7.72e-165	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GNFOHPPO_03252	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
GNFOHPPO_03253	7.13e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GNFOHPPO_03254	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_03255	8.78e-298	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
GNFOHPPO_03256	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
GNFOHPPO_03257	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
GNFOHPPO_03258	3.18e-238	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_03259	1.38e-311	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GNFOHPPO_03260	6.51e-217	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GNFOHPPO_03261	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
GNFOHPPO_03262	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
GNFOHPPO_03263	6.9e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_03264	6.05e-69	ytwF	-	-	P	-	-	-	Sulfurtransferase
GNFOHPPO_03265	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GNFOHPPO_03266	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
GNFOHPPO_03267	3.72e-178	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GNFOHPPO_03268	3.5e-271	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
GNFOHPPO_03269	3.39e-166	ywaF	-	-	S	-	-	-	Integral membrane protein
GNFOHPPO_03270	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
GNFOHPPO_03271	3.81e-173	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03272	4.31e-222	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
GNFOHPPO_03273	4.49e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_03274	3.9e-287	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
GNFOHPPO_03275	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03276	1.05e-208	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
GNFOHPPO_03277	5.05e-233	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GNFOHPPO_03278	6.76e-222	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GNFOHPPO_03279	8.47e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03280	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
GNFOHPPO_03282	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
GNFOHPPO_03283	0.0	-	-	-	IQ	-	-	-	AMP-binding enzyme
GNFOHPPO_03284	3.58e-263	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GNFOHPPO_03285	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03286	0.0	-	-	-	Q	ko:K04784,ko:K12240	ko01053,map01053	ko00000,ko00001,ko01004,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03287	3.89e-241	-	-	-	C	-	-	-	Nitroreductase
GNFOHPPO_03288	4.85e-168	aveG	-	-	Q	-	-	-	Thioesterase domain
GNFOHPPO_03289	0.0	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
GNFOHPPO_03290	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
GNFOHPPO_03291	3.1e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
GNFOHPPO_03293	1.55e-184	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
GNFOHPPO_03294	7.04e-272	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
GNFOHPPO_03295	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
GNFOHPPO_03296	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GNFOHPPO_03297	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_03298	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GNFOHPPO_03299	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GNFOHPPO_03300	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GNFOHPPO_03301	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
GNFOHPPO_03302	1.57e-189	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GNFOHPPO_03303	2.15e-237	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GNFOHPPO_03304	5.03e-183	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GNFOHPPO_03305	7.52e-174	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GNFOHPPO_03306	4.13e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
GNFOHPPO_03307	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
GNFOHPPO_03308	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GNFOHPPO_03310	8.55e-99	ytkA	-	-	S	-	-	-	YtkA-like
GNFOHPPO_03311	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GNFOHPPO_03312	8.41e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
GNFOHPPO_03313	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
GNFOHPPO_03314	8.35e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GNFOHPPO_03315	4.48e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
GNFOHPPO_03316	1.5e-234	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GNFOHPPO_03317	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
GNFOHPPO_03318	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GNFOHPPO_03319	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GNFOHPPO_03320	7.52e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GNFOHPPO_03321	1.52e-200	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GNFOHPPO_03322	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GNFOHPPO_03323	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
GNFOHPPO_03324	1.28e-170	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
GNFOHPPO_03325	2.59e-102	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
GNFOHPPO_03347	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GNFOHPPO_03348	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GNFOHPPO_03349	2.23e-189	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
GNFOHPPO_03350	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GNFOHPPO_03351	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
GNFOHPPO_03352	5.6e-134	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
GNFOHPPO_03353	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
GNFOHPPO_03354	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03355	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
GNFOHPPO_03356	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03357	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03358	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03359	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
GNFOHPPO_03360	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
GNFOHPPO_03361	1.42e-268	-	-	-	V	-	-	-	Beta-lactamase
GNFOHPPO_03362	6.68e-262	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GNFOHPPO_03363	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GNFOHPPO_03364	8.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GNFOHPPO_03365	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GNFOHPPO_03366	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
GNFOHPPO_03367	1.15e-191	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
GNFOHPPO_03368	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
GNFOHPPO_03369	9.4e-57	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
GNFOHPPO_03370	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
GNFOHPPO_03371	7.89e-32	ykzI	-	-	-	-	-	-	-
GNFOHPPO_03372	8.12e-196	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
GNFOHPPO_03373	5.32e-108	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
GNFOHPPO_03374	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
GNFOHPPO_03376	2.64e-60	ylaE	-	-	-	-	-	-	-
GNFOHPPO_03377	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
GNFOHPPO_03378	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GNFOHPPO_03379	6.99e-65	-	-	-	S	-	-	-	YlaH-like protein
GNFOHPPO_03380	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03381	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GNFOHPPO_03382	9.42e-314	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
GNFOHPPO_03383	1.01e-109	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GNFOHPPO_03384	6.57e-224	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GNFOHPPO_03385	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
GNFOHPPO_03386	8.59e-272	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GNFOHPPO_03387	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GNFOHPPO_03388	1.16e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GNFOHPPO_03389	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GNFOHPPO_03390	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GNFOHPPO_03391	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GNFOHPPO_03392	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GNFOHPPO_03393	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GNFOHPPO_03394	4.37e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
GNFOHPPO_03395	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
GNFOHPPO_03396	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_03397	4.44e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
GNFOHPPO_03399	2.38e-202	yybS	-	-	S	-	-	-	membrane
GNFOHPPO_03400	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GNFOHPPO_03401	6.45e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
GNFOHPPO_03402	1.02e-158	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
GNFOHPPO_03403	3.72e-158	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
GNFOHPPO_03404	1.95e-307	-	-	-	M	-	-	-	Glycosyltransferase Family 4
GNFOHPPO_03405	3.8e-296	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
GNFOHPPO_03406	9.85e-263	-	-	-	S	-	-	-	Ecdysteroid kinase
GNFOHPPO_03407	4.41e-306	-	-	-	M	-	-	-	Glycosyltransferase Family 4
GNFOHPPO_03408	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
GNFOHPPO_03410	7.68e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
GNFOHPPO_03411	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GNFOHPPO_03412	1.63e-96	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFOHPPO_03413	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GNFOHPPO_03418	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_03419	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_03420	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03421	1.69e-195	yycI	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03422	9.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GNFOHPPO_03423	6.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNFOHPPO_03424	2.53e-13	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GNFOHPPO_03425	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
GNFOHPPO_03426	2.4e-243	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
GNFOHPPO_03427	0.0	-	-	-	-	-	-	-	-
GNFOHPPO_03428	1.3e-252	-	-	-	S	-	-	-	Major Facilitator Superfamily
GNFOHPPO_03429	0.0	-	-	-	S	-	-	-	ABC transporter
GNFOHPPO_03430	3.73e-188	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
GNFOHPPO_03431	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GNFOHPPO_03432	2.69e-57	sdpR	-	-	K	-	-	-	transcriptional
GNFOHPPO_03433	3.8e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GNFOHPPO_03434	6.81e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
GNFOHPPO_03435	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GNFOHPPO_03436	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
GNFOHPPO_03437	1.11e-260	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
GNFOHPPO_03439	1.69e-112	yycN	-	-	K	-	-	-	Acetyltransferase
GNFOHPPO_03440	5.26e-234	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
GNFOHPPO_03441	5.84e-172	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GNFOHPPO_03442	2.41e-279	yycP	-	-	-	-	-	-	-
GNFOHPPO_03446	7.1e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GNFOHPPO_03447	2.04e-26	spoIVCA	-	-	L	ko:K06400	-	ko00000	Recombinase
GNFOHPPO_03448	1.14e-82	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
GNFOHPPO_03449	5.07e-49	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
GNFOHPPO_03450	3.15e-202	-	-	-	V	-	-	-	Restriction endonuclease
GNFOHPPO_03451	0.0	-	-	-	L	-	-	-	AAA ATPase domain
GNFOHPPO_03452	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
GNFOHPPO_03453	7.35e-56	-	-	-	S	-	-	-	MazG-like family
GNFOHPPO_03454	1.71e-310	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GNFOHPPO_03455	0.0	-	-	-	L	-	-	-	AAA domain
GNFOHPPO_03456	3.35e-76	-	-	-	L	-	-	-	AAA domain
GNFOHPPO_03457	3.65e-33	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
GNFOHPPO_03458	1.4e-237	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
GNFOHPPO_03459	1.77e-238	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GNFOHPPO_03460	6.45e-120	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
GNFOHPPO_03461	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GNFOHPPO_03462	2.71e-197	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GNFOHPPO_03463	9.14e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GNFOHPPO_03464	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
GNFOHPPO_03465	5.26e-314	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
GNFOHPPO_03466	1.68e-293	-	-	-	S	-	-	-	Fic/DOC family
GNFOHPPO_03467	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
GNFOHPPO_03468	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
GNFOHPPO_03469	1.7e-165	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
GNFOHPPO_03470	3.18e-96	yxaI	-	-	S	-	-	-	membrane protein domain
GNFOHPPO_03471	5.4e-256	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GNFOHPPO_03472	1.21e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GNFOHPPO_03473	6.32e-79	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
GNFOHPPO_03474	6.79e-189	yxaL	-	-	S	-	-	-	PQQ-like domain
GNFOHPPO_03475	9.34e-317	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GNFOHPPO_03476	1.33e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GNFOHPPO_03477	6.37e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
GNFOHPPO_03478	2.78e-253	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFOHPPO_03479	1.07e-131	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GNFOHPPO_03480	8.74e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
GNFOHPPO_03482	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
GNFOHPPO_03483	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GNFOHPPO_03484	1.06e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
GNFOHPPO_03485	1.03e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
GNFOHPPO_03486	6.81e-103	gerD	-	-	-	ko:K06294	-	ko00000	-
GNFOHPPO_03487	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GNFOHPPO_03488	1.98e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
GNFOHPPO_03489	1.31e-102	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
GNFOHPPO_03490	2.69e-109	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
GNFOHPPO_03491	1.76e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
GNFOHPPO_03492	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GNFOHPPO_03493	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GNFOHPPO_03494	1.45e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GNFOHPPO_03495	7.93e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFOHPPO_03496	1.41e-189	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFOHPPO_03497	3.56e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFOHPPO_03498	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GNFOHPPO_03499	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFOHPPO_03500	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GNFOHPPO_03501	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GNFOHPPO_03502	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
GNFOHPPO_03503	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GNFOHPPO_03504	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
GNFOHPPO_03505	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GNFOHPPO_03506	1.34e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GNFOHPPO_03507	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
GNFOHPPO_03508	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GNFOHPPO_03509	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GNFOHPPO_03510	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GNFOHPPO_03511	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GNFOHPPO_03512	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GNFOHPPO_03513	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GNFOHPPO_03514	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GNFOHPPO_03515	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GNFOHPPO_03516	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GNFOHPPO_03517	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GNFOHPPO_03518	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GNFOHPPO_03519	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GNFOHPPO_03520	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GNFOHPPO_03521	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GNFOHPPO_03522	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GNFOHPPO_03523	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GNFOHPPO_03524	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GNFOHPPO_03525	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GNFOHPPO_03526	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GNFOHPPO_03527	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GNFOHPPO_03528	2e-240	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
GNFOHPPO_03529	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GNFOHPPO_03530	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GNFOHPPO_03531	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GNFOHPPO_03532	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GNFOHPPO_03533	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
GNFOHPPO_03534	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFOHPPO_03535	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFOHPPO_03536	6.21e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
GNFOHPPO_03537	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GNFOHPPO_03538	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GNFOHPPO_03539	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GNFOHPPO_03540	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GNFOHPPO_03541	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GNFOHPPO_03542	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GNFOHPPO_03543	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
GNFOHPPO_03544	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
GNFOHPPO_03545	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNFOHPPO_03546	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GNFOHPPO_03547	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GNFOHPPO_03548	3.16e-151	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
GNFOHPPO_03549	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GNFOHPPO_03550	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GNFOHPPO_03551	1.18e-158	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GNFOHPPO_03552	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
GNFOHPPO_03553	3.12e-250	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GNFOHPPO_03554	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GNFOHPPO_03555	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
GNFOHPPO_03556	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GNFOHPPO_03557	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
GNFOHPPO_03558	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
GNFOHPPO_03559	5.03e-198	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GNFOHPPO_03560	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
GNFOHPPO_03561	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
GNFOHPPO_03562	2.4e-152	-	-	-	K	-	-	-	FCD domain
GNFOHPPO_03563	7.85e-117	-	-	-	S	-	-	-	PFAM DinB family protein
GNFOHPPO_03564	2.85e-205	-	-	-	G	-	-	-	Major Facilitator Superfamily
GNFOHPPO_03565	2.61e-205	-	-	-	K	-	-	-	LysR substrate binding domain
GNFOHPPO_03566	1.13e-129	-	-	-	E	-	-	-	LysE type translocator
GNFOHPPO_03567	9.23e-73	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GNFOHPPO_03568	1.7e-148	ydgI	-	-	C	-	-	-	nitroreductase
GNFOHPPO_03569	3.36e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
GNFOHPPO_03570	3.25e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
GNFOHPPO_03571	3.2e-100	yybA	-	-	K	-	-	-	transcriptional
GNFOHPPO_03572	3.66e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_03573	5.54e-210	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
GNFOHPPO_03574	2.02e-88	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GNFOHPPO_03575	1.26e-213	-	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_03576	5.17e-180	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GNFOHPPO_03577	9.06e-314	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GNFOHPPO_03578	3e-165	-	-	-	EG	-	-	-	EamA-like transporter family
GNFOHPPO_03579	2.04e-37	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
GNFOHPPO_03580	2.47e-101	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
GNFOHPPO_03581	2.39e-208	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GNFOHPPO_03582	6.93e-42	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
GNFOHPPO_03583	7.88e-131	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GNFOHPPO_03584	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
GNFOHPPO_03585	5.12e-211	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GNFOHPPO_03586	3.75e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
GNFOHPPO_03587	2.42e-88	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFOHPPO_03588	1.51e-231	ccpB	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_03589	1.25e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GNFOHPPO_03590	3.52e-130	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GNFOHPPO_03591	3.77e-138	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
GNFOHPPO_03592	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GNFOHPPO_03593	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GNFOHPPO_03594	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GNFOHPPO_03595	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GNFOHPPO_03596	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GNFOHPPO_03597	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03598	1.67e-225	yyaD	-	-	S	-	-	-	Membrane
GNFOHPPO_03599	5.24e-87	yhhY	-	-	K	-	-	-	FR47-like protein
GNFOHPPO_03600	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
GNFOHPPO_03601	1.43e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GNFOHPPO_03602	1.23e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
GNFOHPPO_03603	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GNFOHPPO_03604	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GNFOHPPO_03605	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GNFOHPPO_03606	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GNFOHPPO_03607	9.37e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
GNFOHPPO_03608	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GNFOHPPO_03609	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GNFOHPPO_03610	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GNFOHPPO_03611	3.45e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GNFOHPPO_03612	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
GNFOHPPO_03613	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GNFOHPPO_03614	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
GNFOHPPO_03615	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GNFOHPPO_03616	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GNFOHPPO_03617	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GNFOHPPO_03618	2.17e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNFOHPPO_03619	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
GNFOHPPO_03620	8.2e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GNFOHPPO_03621	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GNFOHPPO_03622	2.24e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GNFOHPPO_03623	8.13e-206	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
GNFOHPPO_03624	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
GNFOHPPO_03625	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GNFOHPPO_03626	8.88e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GNFOHPPO_03627	2.5e-201	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
GNFOHPPO_03628	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GNFOHPPO_03629	6.64e-187	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GNFOHPPO_03630	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GNFOHPPO_03631	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
GNFOHPPO_03632	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GNFOHPPO_03633	7.77e-235	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GNFOHPPO_03634	3.79e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
GNFOHPPO_03635	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
GNFOHPPO_03638	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
GNFOHPPO_03639	1.2e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GNFOHPPO_03640	1.67e-134	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
GNFOHPPO_03641	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
GNFOHPPO_03642	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GNFOHPPO_03643	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GNFOHPPO_03644	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GNFOHPPO_03645	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
GNFOHPPO_03646	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GNFOHPPO_03647	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
GNFOHPPO_03648	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GNFOHPPO_03649	2.15e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GNFOHPPO_03650	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GNFOHPPO_03651	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GNFOHPPO_03652	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GNFOHPPO_03653	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
GNFOHPPO_03654	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GNFOHPPO_03655	2.73e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GNFOHPPO_03656	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
GNFOHPPO_03657	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03658	1.41e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
GNFOHPPO_03659	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GNFOHPPO_03660	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GNFOHPPO_03661	2.49e-310	yabE	-	-	T	-	-	-	protein conserved in bacteria
GNFOHPPO_03662	6.12e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
GNFOHPPO_03663	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GNFOHPPO_03664	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
GNFOHPPO_03665	2.01e-210	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GNFOHPPO_03666	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
GNFOHPPO_03667	8.05e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
GNFOHPPO_03668	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GNFOHPPO_03669	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
GNFOHPPO_03670	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GNFOHPPO_03671	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
GNFOHPPO_03672	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
GNFOHPPO_03673	7.75e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GNFOHPPO_03674	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
GNFOHPPO_03675	4.89e-244	yaaN	-	-	P	-	-	-	Belongs to the TelA family
GNFOHPPO_03676	7.19e-137	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GNFOHPPO_03677	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
GNFOHPPO_03678	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GNFOHPPO_03679	5.65e-160	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
GNFOHPPO_03680	2.5e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
GNFOHPPO_03681	3.79e-92	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
GNFOHPPO_03682	3.22e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GNFOHPPO_03683	1.16e-139	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
GNFOHPPO_03684	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GNFOHPPO_03685	8.63e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
GNFOHPPO_03686	3.33e-207	yhcP	-	-	-	-	-	-	-
GNFOHPPO_03687	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GNFOHPPO_03688	9.56e-81	yhcM	-	-	-	-	-	-	-
GNFOHPPO_03689	1.29e-293	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GNFOHPPO_03690	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
GNFOHPPO_03691	4.82e-189	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GNFOHPPO_03692	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
GNFOHPPO_03693	4.49e-209	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GNFOHPPO_03694	9.59e-215	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03695	1.4e-159	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFOHPPO_03696	4.71e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_03697	2.33e-66	-	-	-	-	-	-	-	-
GNFOHPPO_03698	1.41e-72	yhcC	-	-	-	-	-	-	-
GNFOHPPO_03699	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GNFOHPPO_03700	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
GNFOHPPO_03701	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
GNFOHPPO_03702	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
GNFOHPPO_03703	1.77e-280	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
GNFOHPPO_03704	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
GNFOHPPO_03705	1.23e-07	-	-	-	-	-	-	-	-
GNFOHPPO_03706	6.68e-93	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
GNFOHPPO_03707	9.86e-86	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
GNFOHPPO_03708	3.4e-141	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
GNFOHPPO_03709	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GNFOHPPO_03710	8.65e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
GNFOHPPO_03711	1.2e-286	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GNFOHPPO_03712	1.58e-146	yhzB	-	-	S	-	-	-	B3/4 domain
GNFOHPPO_03714	9.41e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_03715	6.39e-107	ygaO	-	-	-	-	-	-	-
GNFOHPPO_03716	2.39e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GNFOHPPO_03717	3.51e-272	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
GNFOHPPO_03718	4.78e-185	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
GNFOHPPO_03719	4.48e-232	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
GNFOHPPO_03720	4.5e-180	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GNFOHPPO_03721	1.63e-234	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
GNFOHPPO_03722	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
GNFOHPPO_03723	5.71e-169	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_03724	4.46e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GNFOHPPO_03725	1.77e-161	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GNFOHPPO_03726	1.42e-179	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GNFOHPPO_03727	3.65e-290	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
GNFOHPPO_03729	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
GNFOHPPO_03730	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GNFOHPPO_03731	2.83e-171	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
GNFOHPPO_03732	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
GNFOHPPO_03749	2.92e-52	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
GNFOHPPO_03750	3.69e-131	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GNFOHPPO_03751	1.61e-72	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
GNFOHPPO_03752	1.45e-60	-	-	-	-	-	-	-	-
GNFOHPPO_03753	4.67e-128	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GNFOHPPO_03755	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GNFOHPPO_03756	5.15e-247	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFOHPPO_03757	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
GNFOHPPO_03758	7.72e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
GNFOHPPO_03759	1.14e-180	yoxB	-	-	-	-	-	-	-
GNFOHPPO_03760	5.45e-53	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GNFOHPPO_03761	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFOHPPO_03762	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GNFOHPPO_03763	1.69e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNFOHPPO_03764	2.31e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GNFOHPPO_03765	1.76e-203	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_03766	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
GNFOHPPO_03767	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GNFOHPPO_03768	3.58e-239	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GNFOHPPO_03769	2.23e-200	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
GNFOHPPO_03770	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GNFOHPPO_03771	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
GNFOHPPO_03772	3.38e-256	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
GNFOHPPO_03773	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
GNFOHPPO_03774	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
GNFOHPPO_03775	9.36e-124	-	-	-	L	-	-	-	Integrase
GNFOHPPO_03777	4.47e-126	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
GNFOHPPO_03778	5.24e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
GNFOHPPO_03779	9.55e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GNFOHPPO_03780	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
GNFOHPPO_03781	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
GNFOHPPO_03782	1.25e-141	ywbG	-	-	M	-	-	-	effector of murein hydrolase
GNFOHPPO_03783	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GNFOHPPO_03784	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
GNFOHPPO_03785	1.12e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GNFOHPPO_03786	1.17e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GNFOHPPO_03787	1.08e-309	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
GNFOHPPO_03788	8.86e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
GNFOHPPO_03789	1.64e-170	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
GNFOHPPO_03790	6.16e-167	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
GNFOHPPO_03792	3.72e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GNFOHPPO_03793	1.71e-81	gtcA	-	-	S	-	-	-	GtrA-like protein
GNFOHPPO_03794	1.54e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GNFOHPPO_03795	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GNFOHPPO_03796	5.74e-48	ydaS	-	-	S	-	-	-	membrane
GNFOHPPO_03797	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GNFOHPPO_03798	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GNFOHPPO_03799	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
GNFOHPPO_03800	8.22e-85	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
GNFOHPPO_03801	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
GNFOHPPO_03802	6.66e-104	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
GNFOHPPO_03803	1.58e-263	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GNFOHPPO_03804	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
GNFOHPPO_03805	2.02e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
GNFOHPPO_03806	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GNFOHPPO_03807	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GNFOHPPO_03808	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GNFOHPPO_03809	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GNFOHPPO_03810	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GNFOHPPO_03811	1.77e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GNFOHPPO_03813	1.25e-157	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
GNFOHPPO_03814	4.04e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
GNFOHPPO_03815	1.75e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
GNFOHPPO_03816	3.53e-129	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
GNFOHPPO_03817	7.1e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GNFOHPPO_03818	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GNFOHPPO_03819	2.41e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GNFOHPPO_03820	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GNFOHPPO_03821	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GNFOHPPO_03822	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
GNFOHPPO_03823	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03824	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03826	9.38e-126	-	-	-	S	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved WHH
GNFOHPPO_03827	2.48e-110	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
GNFOHPPO_03828	3.06e-51	-	-	-	H	-	-	-	Acetyltransferase (GNAT) domain
GNFOHPPO_03830	5.76e-247	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
GNFOHPPO_03831	6.71e-102	yoqH	-	-	M	-	-	-	LysM domain
GNFOHPPO_03836	0.0	yokA	-	-	L	-	-	-	Recombinase
GNFOHPPO_03837	5.15e-109	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
GNFOHPPO_03838	1.73e-108	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
GNFOHPPO_03839	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFOHPPO_03840	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
GNFOHPPO_03846	4.69e-172	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
GNFOHPPO_03847	1.55e-72	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
GNFOHPPO_03848	2.04e-66	-	-	-	L	-	-	-	transposase activity
GNFOHPPO_03849	1.75e-151	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination