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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NIEBEHDK_00004	2.36e-124	-	-	-	S	-	-	-	Siphovirus ReqiPepy6 Gp37-like protein
NIEBEHDK_00005	7.67e-100	-	-	-	K	-	-	-	Putative sugar-binding domain
NIEBEHDK_00007	1.16e-38	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
NIEBEHDK_00008	2.96e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NIEBEHDK_00009	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
NIEBEHDK_00010	6.88e-45	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NIEBEHDK_00011	1.49e-36	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NIEBEHDK_00012	4.62e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NIEBEHDK_00013	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NIEBEHDK_00014	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NIEBEHDK_00015	7.09e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
NIEBEHDK_00016	6.48e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_00017	6.94e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NIEBEHDK_00018	8.54e-88	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIEBEHDK_00019	1.26e-104	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIEBEHDK_00020	1.12e-303	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_00021	2.32e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIEBEHDK_00022	3.78e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIEBEHDK_00023	3.14e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NIEBEHDK_00024	4.88e-215	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NIEBEHDK_00025	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NIEBEHDK_00026	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
NIEBEHDK_00027	3.5e-163	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NIEBEHDK_00028	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_00029	4.73e-294	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_00030	1.35e-81	-	-	-	-	-	-	-	-
NIEBEHDK_00031	4.55e-95	-	-	-	-	-	-	-	-
NIEBEHDK_00032	1.81e-150	-	-	-	-	-	-	-	-
NIEBEHDK_00033	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
NIEBEHDK_00034	3.9e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIEBEHDK_00035	1.74e-111	-	-	-	-	-	-	-	-
NIEBEHDK_00036	0.0	manR	-	-	G	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_00037	1.34e-88	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_00038	1.31e-305	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_00039	1.19e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NIEBEHDK_00040	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NIEBEHDK_00041	1.15e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
NIEBEHDK_00042	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIEBEHDK_00043	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NIEBEHDK_00044	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_00045	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_00046	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_00047	1.11e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_00048	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NIEBEHDK_00049	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIEBEHDK_00050	1.33e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NIEBEHDK_00051	3.79e-293	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NIEBEHDK_00052	9.39e-256	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NIEBEHDK_00053	1.23e-194	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_00054	5.56e-103	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_00055	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_00056	3.76e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_00057	1.17e-247	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
NIEBEHDK_00058	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_00059	1.3e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NIEBEHDK_00060	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NIEBEHDK_00061	5.5e-155	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
NIEBEHDK_00063	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
NIEBEHDK_00064	4.39e-34	-	-	-	-	-	-	-	-
NIEBEHDK_00065	3.19e-49	-	-	-	-	-	-	-	-
NIEBEHDK_00066	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NIEBEHDK_00067	1.33e-311	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIEBEHDK_00068	1.55e-141	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NIEBEHDK_00069	5.44e-163	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIEBEHDK_00070	1.46e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
NIEBEHDK_00071	6.35e-100	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIEBEHDK_00072	7.84e-74	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIEBEHDK_00073	5.6e-132	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIEBEHDK_00074	4.28e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NIEBEHDK_00075	0.0	-	-	-	E	-	-	-	Amino acid permease
NIEBEHDK_00076	1.16e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NIEBEHDK_00077	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIEBEHDK_00078	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIEBEHDK_00079	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIEBEHDK_00080	1.13e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
NIEBEHDK_00081	4.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIEBEHDK_00082	3.31e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NIEBEHDK_00083	2.19e-101	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NIEBEHDK_00084	0.000236	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	alpha-ribazole phosphatase activity
NIEBEHDK_00085	2.34e-66	cobD2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Cytoplasmic, score
NIEBEHDK_00086	1.36e-47	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_00087	1.11e-20	-	-	-	L	-	-	-	DNA packaging
NIEBEHDK_00088	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_00089	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIEBEHDK_00090	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIEBEHDK_00091	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIEBEHDK_00092	4.99e-252	-	-	-	K	-	-	-	WYL domain
NIEBEHDK_00093	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NIEBEHDK_00094	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NIEBEHDK_00095	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NIEBEHDK_00096	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIEBEHDK_00097	3.43e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NIEBEHDK_00098	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIEBEHDK_00099	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIEBEHDK_00100	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIEBEHDK_00101	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIEBEHDK_00102	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIEBEHDK_00103	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIEBEHDK_00104	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NIEBEHDK_00105	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIEBEHDK_00106	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIEBEHDK_00107	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIEBEHDK_00108	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIEBEHDK_00109	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIEBEHDK_00110	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIEBEHDK_00111	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIEBEHDK_00112	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIEBEHDK_00113	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NIEBEHDK_00114	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NIEBEHDK_00115	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIEBEHDK_00116	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIEBEHDK_00117	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIEBEHDK_00118	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NIEBEHDK_00119	2.66e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIEBEHDK_00120	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIEBEHDK_00121	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEBEHDK_00122	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NIEBEHDK_00123	3.39e-148	-	-	-	-	-	-	-	-
NIEBEHDK_00124	2.32e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEBEHDK_00125	4.3e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEBEHDK_00126	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEBEHDK_00127	1.44e-30	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIEBEHDK_00128	9.7e-135	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIEBEHDK_00129	3.52e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
NIEBEHDK_00130	1.28e-45	-	-	-	-	-	-	-	-
NIEBEHDK_00131	3.01e-163	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00132	7.16e-236	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIEBEHDK_00133	7.98e-43	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_00134	7.22e-70	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_00135	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIEBEHDK_00136	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NIEBEHDK_00137	4.36e-265	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NIEBEHDK_00138	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NIEBEHDK_00139	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIEBEHDK_00141	3.92e-28	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NIEBEHDK_00143	1.06e-156	-	-	-	S	-	-	-	B3/4 domain
NIEBEHDK_00144	6.12e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIEBEHDK_00145	5.81e-155	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00146	5.68e-298	-	-	-	I	-	-	-	Acyltransferase family
NIEBEHDK_00147	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
NIEBEHDK_00148	2.26e-218	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
NIEBEHDK_00149	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
NIEBEHDK_00150	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NIEBEHDK_00151	5.96e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEBEHDK_00152	3.3e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEBEHDK_00154	2.99e-27	-	-	-	-	-	-	-	-
NIEBEHDK_00155	3.31e-208	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NIEBEHDK_00156	7.54e-113	-	-	-	-	-	-	-	-
NIEBEHDK_00157	1.4e-152	-	-	-	GM	-	-	-	NmrA-like family
NIEBEHDK_00158	5.54e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NIEBEHDK_00159	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEBEHDK_00160	1.61e-168	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIEBEHDK_00161	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NIEBEHDK_00162	1.55e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NIEBEHDK_00163	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NIEBEHDK_00164	2.4e-144	-	-	-	P	-	-	-	Cation efflux family
NIEBEHDK_00165	2.5e-34	-	-	-	-	-	-	-	-
NIEBEHDK_00166	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NIEBEHDK_00167	6.76e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_00168	4.42e-84	-	-	-	-	-	-	-	-
NIEBEHDK_00169	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_00170	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NIEBEHDK_00171	7.48e-25	-	-	-	-	-	-	-	-
NIEBEHDK_00172	2.75e-22	-	-	-	-	-	-	-	-
NIEBEHDK_00173	3.34e-58	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIEBEHDK_00175	1.64e-31	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIEBEHDK_00176	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NIEBEHDK_00177	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NIEBEHDK_00178	1.41e-125	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIEBEHDK_00179	5.89e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NIEBEHDK_00180	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NIEBEHDK_00181	2.79e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NIEBEHDK_00182	9.09e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NIEBEHDK_00183	1.48e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIEBEHDK_00184	1.03e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIEBEHDK_00185	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00186	2.08e-110	-	-	-	-	-	-	-	-
NIEBEHDK_00187	2.42e-161	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIEBEHDK_00188	5.47e-101	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIEBEHDK_00189	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEBEHDK_00190	3.7e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NIEBEHDK_00191	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIEBEHDK_00192	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NIEBEHDK_00193	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NIEBEHDK_00194	1.09e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NIEBEHDK_00195	6.23e-87	-	-	-	M	-	-	-	Lysin motif
NIEBEHDK_00196	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NIEBEHDK_00197	1.83e-231	-	-	-	S	-	-	-	Helix-turn-helix domain
NIEBEHDK_00198	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
NIEBEHDK_00199	4.54e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIEBEHDK_00200	2.34e-111	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NIEBEHDK_00201	8.13e-43	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NIEBEHDK_00202	6.34e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIEBEHDK_00203	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIEBEHDK_00204	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIEBEHDK_00205	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NIEBEHDK_00206	7.26e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NIEBEHDK_00207	7.15e-94	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
NIEBEHDK_00208	3.85e-71	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NIEBEHDK_00209	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NIEBEHDK_00210	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIEBEHDK_00211	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NIEBEHDK_00212	2.92e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NIEBEHDK_00213	2.15e-187	-	-	-	-	-	-	-	-
NIEBEHDK_00214	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NIEBEHDK_00215	3.37e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NIEBEHDK_00216	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NIEBEHDK_00217	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIEBEHDK_00218	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NIEBEHDK_00219	8.77e-155	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NIEBEHDK_00220	2.92e-232	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIEBEHDK_00221	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NIEBEHDK_00222	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIEBEHDK_00223	3.1e-112	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_00224	6.83e-33	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_00225	1.21e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEBEHDK_00226	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NIEBEHDK_00227	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIEBEHDK_00228	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00229	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00230	2.34e-28	-	-	-	-	-	-	-	-
NIEBEHDK_00231	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NIEBEHDK_00232	2.24e-69	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NIEBEHDK_00233	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIEBEHDK_00234	8.34e-271	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIEBEHDK_00235	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
NIEBEHDK_00236	2.93e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NIEBEHDK_00237	1.12e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NIEBEHDK_00238	1.02e-171	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NIEBEHDK_00239	1.14e-108	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NIEBEHDK_00240	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIEBEHDK_00241	5.38e-170	-	-	-	S	-	-	-	Tetratricopeptide repeat
NIEBEHDK_00242	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEBEHDK_00243	6.79e-152	-	-	-	-	-	-	-	-
NIEBEHDK_00244	1.91e-38	-	-	-	-	-	-	-	-
NIEBEHDK_00245	8.15e-241	-	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_00246	3.84e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
NIEBEHDK_00247	1.43e-224	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_00248	3.44e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
NIEBEHDK_00249	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
NIEBEHDK_00250	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
NIEBEHDK_00251	2.49e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_00252	2.46e-120	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NIEBEHDK_00253	2.4e-15	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NIEBEHDK_00254	4.96e-270	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIEBEHDK_00255	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NIEBEHDK_00256	4.79e-21	-	-	-	-	-	-	-	-
NIEBEHDK_00257	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NIEBEHDK_00258	3.38e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
NIEBEHDK_00259	5.27e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIEBEHDK_00260	1.22e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NIEBEHDK_00262	1.34e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NIEBEHDK_00263	3.18e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NIEBEHDK_00264	8.01e-254	-	-	-	-	-	-	-	-
NIEBEHDK_00266	2.6e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
NIEBEHDK_00267	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
NIEBEHDK_00269	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
NIEBEHDK_00270	3.27e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_00271	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIEBEHDK_00272	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00273	2.27e-220	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NIEBEHDK_00274	7.17e-225	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NIEBEHDK_00275	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NIEBEHDK_00276	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
NIEBEHDK_00277	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NIEBEHDK_00278	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
NIEBEHDK_00279	1.59e-14	-	-	-	-	-	-	-	-
NIEBEHDK_00280	3.17e-11	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEBEHDK_00281	6.13e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
NIEBEHDK_00282	1.87e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NIEBEHDK_00283	1.99e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NIEBEHDK_00284	1.19e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
NIEBEHDK_00285	7.2e-260	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
NIEBEHDK_00288	1.29e-07	rggD	-	-	K	-	-	-	Transcriptional regulator RggD
NIEBEHDK_00292	7.15e-232	-	-	-	K	-	-	-	sequence-specific DNA binding
NIEBEHDK_00293	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NIEBEHDK_00294	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NIEBEHDK_00295	1.71e-64	-	-	-	-	-	-	-	-
NIEBEHDK_00296	7.49e-237	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIEBEHDK_00297	5.83e-75	-	-	-	-	-	-	-	-
NIEBEHDK_00298	6.82e-104	-	-	-	-	-	-	-	-
NIEBEHDK_00299	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
NIEBEHDK_00300	1.99e-36	-	-	-	-	-	-	-	-
NIEBEHDK_00301	5.8e-129	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIEBEHDK_00302	1.81e-98	-	-	-	-	-	-	-	-
NIEBEHDK_00303	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NIEBEHDK_00304	9.06e-136	-	-	-	S	-	-	-	Flavin reductase like domain
NIEBEHDK_00305	8.46e-177	-	-	-	-	-	-	-	-
NIEBEHDK_00306	1e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIEBEHDK_00307	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NIEBEHDK_00308	8.59e-221	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NIEBEHDK_00309	6.96e-206	mleR	-	-	K	-	-	-	LysR family
NIEBEHDK_00310	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NIEBEHDK_00311	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NIEBEHDK_00312	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
NIEBEHDK_00313	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NIEBEHDK_00314	2.87e-106	-	-	-	S	-	-	-	NusG domain II
NIEBEHDK_00315	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
NIEBEHDK_00316	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIEBEHDK_00317	9.18e-105	-	-	-	-	-	-	-	-
NIEBEHDK_00318	3.41e-187	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NIEBEHDK_00319	5.81e-125	-	-	-	-	-	-	-	-
NIEBEHDK_00320	1.29e-202	-	-	-	-	-	-	-	-
NIEBEHDK_00321	3.67e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00322	8.22e-273	-	-	-	-	-	-	-	-
NIEBEHDK_00323	4.05e-247	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NIEBEHDK_00324	2.58e-155	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
NIEBEHDK_00325	3.64e-249	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NIEBEHDK_00326	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
NIEBEHDK_00327	2.6e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEBEHDK_00328	2.3e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIEBEHDK_00329	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIEBEHDK_00330	4.31e-312	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NIEBEHDK_00331	1.43e-67	-	-	-	-	-	-	-	-
NIEBEHDK_00332	5.23e-41	-	-	-	-	-	-	-	-
NIEBEHDK_00334	6.07e-189	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIEBEHDK_00335	3.64e-138	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIEBEHDK_00336	1.36e-179	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NIEBEHDK_00337	4.58e-225	-	-	-	S	-	-	-	Membrane
NIEBEHDK_00338	3.54e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NIEBEHDK_00339	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_00340	6.07e-292	inlJ	-	-	M	-	-	-	MucBP domain
NIEBEHDK_00341	6.42e-88	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIEBEHDK_00342	9.79e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00343	1.12e-138	-	-	-	K	-	-	-	sequence-specific DNA binding
NIEBEHDK_00344	1.22e-93	yacL	-	-	S	-	-	-	domain protein
NIEBEHDK_00345	5.62e-145	yacL	-	-	S	-	-	-	domain protein
NIEBEHDK_00346	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIEBEHDK_00347	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
NIEBEHDK_00348	2.37e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NIEBEHDK_00349	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NIEBEHDK_00350	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NIEBEHDK_00351	1.42e-249	-	-	-	-	-	-	-	-
NIEBEHDK_00352	7.65e-272	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIEBEHDK_00353	2.55e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00354	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NIEBEHDK_00355	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
NIEBEHDK_00356	2.36e-119	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
NIEBEHDK_00357	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEBEHDK_00358	1.1e-256	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NIEBEHDK_00359	5.45e-61	-	-	-	-	-	-	-	-
NIEBEHDK_00360	2.43e-264	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NIEBEHDK_00361	9.49e-26	-	-	-	S	-	-	-	CsbD-like
NIEBEHDK_00362	9.56e-189	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIEBEHDK_00363	3.49e-242	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NIEBEHDK_00364	4.06e-146	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
NIEBEHDK_00365	3.92e-218	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NIEBEHDK_00366	9.32e-118	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
NIEBEHDK_00368	2.13e-44	-	-	-	-	-	-	-	-
NIEBEHDK_00369	4.69e-46	-	-	-	-	-	-	-	-
NIEBEHDK_00370	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NIEBEHDK_00371	5.56e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIEBEHDK_00372	1.38e-189	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIEBEHDK_00374	3.96e-120	-	-	-	-	-	-	-	-
NIEBEHDK_00375	1.84e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NIEBEHDK_00376	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
NIEBEHDK_00377	1.34e-94	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NIEBEHDK_00378	4.72e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NIEBEHDK_00379	1.76e-144	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NIEBEHDK_00380	1.01e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIEBEHDK_00381	2.9e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NIEBEHDK_00382	1.4e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIEBEHDK_00383	5.95e-212	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
NIEBEHDK_00384	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NIEBEHDK_00385	3.98e-171	-	-	-	F	-	-	-	deoxynucleoside kinase
NIEBEHDK_00386	9.53e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NIEBEHDK_00387	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NIEBEHDK_00388	1.15e-204	-	-	-	T	-	-	-	GHKL domain
NIEBEHDK_00389	1.38e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NIEBEHDK_00390	4.56e-215	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NIEBEHDK_00391	8.81e-166	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIEBEHDK_00392	1.2e-207	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_00393	1.63e-103	yphH	-	-	S	-	-	-	Cupin domain
NIEBEHDK_00394	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NIEBEHDK_00395	4.39e-06	-	-	-	-	-	-	-	-
NIEBEHDK_00396	5.9e-15	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_00397	1.14e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_00398	1.72e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00399	4.66e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00400	8.05e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NIEBEHDK_00401	1.04e-135	-	-	-	-	-	-	-	-
NIEBEHDK_00402	2.93e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NIEBEHDK_00403	1.62e-256	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIEBEHDK_00404	6.21e-165	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NIEBEHDK_00405	1.83e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_00406	0.0	-	-	-	-	-	-	-	-
NIEBEHDK_00407	4.64e-188	-	-	-	-	-	-	-	-
NIEBEHDK_00408	3.68e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00409	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NIEBEHDK_00410	2.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NIEBEHDK_00411	1.13e-289	-	-	-	E	-	-	-	Amino acid permease
NIEBEHDK_00412	1.08e-27	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NIEBEHDK_00413	1.47e-102	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NIEBEHDK_00414	2.45e-175	-	-	-	S	-	-	-	Domain of unknown function (DUF1998)
NIEBEHDK_00415	0.0	-	-	-	KL	-	-	-	Helicase conserved C-terminal domain
NIEBEHDK_00417	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIEBEHDK_00418	6.83e-109	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NIEBEHDK_00419	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIEBEHDK_00420	7.69e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NIEBEHDK_00421	1.73e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIEBEHDK_00422	3.97e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
NIEBEHDK_00423	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIEBEHDK_00424	5.13e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NIEBEHDK_00425	1.63e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NIEBEHDK_00426	2.01e-151	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NIEBEHDK_00427	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NIEBEHDK_00428	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NIEBEHDK_00429	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NIEBEHDK_00430	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NIEBEHDK_00431	6.07e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NIEBEHDK_00432	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00433	1.29e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
NIEBEHDK_00434	3.16e-31	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NIEBEHDK_00435	3.09e-148	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NIEBEHDK_00436	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIEBEHDK_00437	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NIEBEHDK_00438	7.05e-248	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NIEBEHDK_00439	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NIEBEHDK_00440	1.96e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NIEBEHDK_00441	2.04e-247	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NIEBEHDK_00442	2.96e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIEBEHDK_00443	2.89e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NIEBEHDK_00444	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NIEBEHDK_00445	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NIEBEHDK_00446	3.76e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NIEBEHDK_00447	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NIEBEHDK_00448	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NIEBEHDK_00449	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NIEBEHDK_00450	1.19e-199	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
NIEBEHDK_00451	8.92e-249	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NIEBEHDK_00452	1.43e-50	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NIEBEHDK_00453	6.23e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIEBEHDK_00454	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NIEBEHDK_00455	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NIEBEHDK_00456	8.12e-174	-	-	-	S	-	-	-	E1-E2 ATPase
NIEBEHDK_00457	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIEBEHDK_00458	1.83e-35	-	-	-	-	-	-	-	-
NIEBEHDK_00459	2.95e-96	-	-	-	-	-	-	-	-
NIEBEHDK_00461	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NIEBEHDK_00462	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEBEHDK_00463	3.62e-62	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NIEBEHDK_00464	8.39e-148	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NIEBEHDK_00465	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
NIEBEHDK_00466	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIEBEHDK_00467	8.3e-150	-	-	-	S	-	-	-	repeat protein
NIEBEHDK_00468	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NIEBEHDK_00469	8.38e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIEBEHDK_00470	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
NIEBEHDK_00471	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NIEBEHDK_00472	9.79e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NIEBEHDK_00473	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIEBEHDK_00474	1.36e-46	-	-	-	-	-	-	-	-
NIEBEHDK_00475	1.56e-127	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NIEBEHDK_00476	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NIEBEHDK_00477	1.21e-267	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
NIEBEHDK_00478	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_00479	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NIEBEHDK_00480	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NIEBEHDK_00481	2.29e-62	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIEBEHDK_00482	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIEBEHDK_00483	2.93e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
NIEBEHDK_00484	1.91e-185	ylmH	-	-	S	-	-	-	S4 domain protein
NIEBEHDK_00485	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
NIEBEHDK_00486	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIEBEHDK_00487	2.19e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIEBEHDK_00488	6.05e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIEBEHDK_00489	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIEBEHDK_00490	3.84e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIEBEHDK_00491	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIEBEHDK_00492	3.67e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIEBEHDK_00493	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NIEBEHDK_00494	9.47e-108	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NIEBEHDK_00495	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
NIEBEHDK_00496	4.57e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIEBEHDK_00497	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NIEBEHDK_00498	1.49e-70	-	-	-	-	-	-	-	-
NIEBEHDK_00499	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NIEBEHDK_00500	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEBEHDK_00501	3.61e-83	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_00502	5.92e-276	-	-	-	-	-	-	-	-
NIEBEHDK_00503	0.0	-	-	-	-	-	-	-	-
NIEBEHDK_00505	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
NIEBEHDK_00507	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NIEBEHDK_00508	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIEBEHDK_00509	5.29e-238	mocA	-	-	S	-	-	-	Oxidoreductase
NIEBEHDK_00510	2.75e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_00511	1.6e-145	-	-	-	S	-	-	-	Flavodoxin-like fold
NIEBEHDK_00513	1.05e-79	-	-	-	-	-	-	-	-
NIEBEHDK_00514	3.45e-37	-	-	-	-	-	-	-	-
NIEBEHDK_00515	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NIEBEHDK_00516	1.1e-50	-	-	-	-	-	-	-	-
NIEBEHDK_00517	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NIEBEHDK_00518	2.02e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
NIEBEHDK_00519	5.37e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NIEBEHDK_00520	7.38e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIEBEHDK_00521	1.7e-70	-	-	-	-	-	-	-	-
NIEBEHDK_00522	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEBEHDK_00523	2.17e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIEBEHDK_00524	2.95e-147	-	-	-	J	-	-	-	HAD-hyrolase-like
NIEBEHDK_00525	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NIEBEHDK_00526	1.48e-50	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
NIEBEHDK_00527	8.06e-200	-	-	-	V	-	-	-	ABC transporter
NIEBEHDK_00528	7.14e-61	-	-	-	-	-	-	-	-
NIEBEHDK_00529	9.92e-66	-	-	-	-	-	-	-	-
NIEBEHDK_00530	7.79e-145	-	-	-	-	-	-	-	-
NIEBEHDK_00531	1.8e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NIEBEHDK_00532	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIEBEHDK_00533	1.26e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NIEBEHDK_00534	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEBEHDK_00535	1.02e-146	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIEBEHDK_00536	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIEBEHDK_00537	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NIEBEHDK_00538	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NIEBEHDK_00539	6.59e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NIEBEHDK_00540	5.09e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIEBEHDK_00541	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NIEBEHDK_00542	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NIEBEHDK_00543	5.57e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIEBEHDK_00544	4.96e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NIEBEHDK_00545	7.35e-70	-	-	-	-	-	-	-	-
NIEBEHDK_00546	1.08e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00548	1.15e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NIEBEHDK_00549	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NIEBEHDK_00550	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NIEBEHDK_00551	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIEBEHDK_00552	1.21e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIEBEHDK_00553	1.39e-130	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NIEBEHDK_00554	1.83e-187	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIEBEHDK_00555	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_00556	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
NIEBEHDK_00557	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NIEBEHDK_00558	1.15e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NIEBEHDK_00559	5.06e-181	-	-	-	-	-	-	-	-
NIEBEHDK_00560	1.54e-222	-	-	-	-	-	-	-	-
NIEBEHDK_00561	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NIEBEHDK_00562	7.36e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIEBEHDK_00563	3.66e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NIEBEHDK_00564	4.19e-212	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NIEBEHDK_00565	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIEBEHDK_00566	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NIEBEHDK_00567	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NIEBEHDK_00568	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NIEBEHDK_00569	3.43e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NIEBEHDK_00570	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NIEBEHDK_00571	9.49e-143	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NIEBEHDK_00572	5.04e-130	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIEBEHDK_00573	7.79e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NIEBEHDK_00574	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NIEBEHDK_00575	4.21e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIEBEHDK_00576	1.54e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NIEBEHDK_00577	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIEBEHDK_00579	5.02e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NIEBEHDK_00580	1.05e-221	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NIEBEHDK_00581	7.29e-46	-	-	-	-	-	-	-	-
NIEBEHDK_00582	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NIEBEHDK_00583	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NIEBEHDK_00584	2.53e-210	lysR	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_00586	2.95e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIEBEHDK_00587	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIEBEHDK_00588	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NIEBEHDK_00589	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_00590	4.86e-05	-	-	-	-	-	-	-	-
NIEBEHDK_00591	5.46e-72	-	-	-	-	-	-	-	-
NIEBEHDK_00592	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEBEHDK_00593	1.72e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NIEBEHDK_00594	5.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NIEBEHDK_00595	5.76e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
NIEBEHDK_00596	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NIEBEHDK_00597	1.99e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIEBEHDK_00598	1.74e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIEBEHDK_00599	3.67e-126	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIEBEHDK_00600	2.33e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NIEBEHDK_00601	5.88e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NIEBEHDK_00602	2.76e-306	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIEBEHDK_00603	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NIEBEHDK_00604	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NIEBEHDK_00605	9.32e-194	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIEBEHDK_00606	1.55e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIEBEHDK_00607	3.69e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIEBEHDK_00608	4.28e-198	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NIEBEHDK_00609	2.22e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NIEBEHDK_00611	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NIEBEHDK_00612	1.68e-50	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
NIEBEHDK_00613	1.37e-221	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
NIEBEHDK_00614	9.86e-231	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
NIEBEHDK_00615	1.02e-183	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEBEHDK_00616	7.08e-171	-	-	-	M	-	-	-	Sortase family
NIEBEHDK_00617	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NIEBEHDK_00618	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NIEBEHDK_00619	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NIEBEHDK_00620	2.13e-258	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NIEBEHDK_00621	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NIEBEHDK_00623	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIEBEHDK_00624	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NIEBEHDK_00625	6.3e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIEBEHDK_00626	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NIEBEHDK_00627	5.22e-207	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIEBEHDK_00628	6.53e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIEBEHDK_00629	8.57e-203	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NIEBEHDK_00630	9.55e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00631	8.86e-145	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NIEBEHDK_00632	1.1e-13	-	-	-	-	-	-	-	-
NIEBEHDK_00633	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NIEBEHDK_00634	0.000417	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NIEBEHDK_00635	1.95e-221	-	-	-	-	-	-	-	-
NIEBEHDK_00636	1.05e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00638	5.86e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NIEBEHDK_00639	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00640	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00641	4.63e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NIEBEHDK_00642	7.75e-146	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NIEBEHDK_00643	1.09e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
NIEBEHDK_00644	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
NIEBEHDK_00645	1.41e-115	-	-	-	-	-	-	-	-
NIEBEHDK_00646	4.48e-254	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIEBEHDK_00647	8.66e-202	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
NIEBEHDK_00648	3.19e-142	-	-	-	M	-	-	-	Acyltransferase family
NIEBEHDK_00649	1.42e-224	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NIEBEHDK_00650	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NIEBEHDK_00651	1.03e-275	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NIEBEHDK_00652	2.17e-150	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_00653	2.61e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
NIEBEHDK_00654	6.29e-314	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NIEBEHDK_00655	1.45e-126	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
NIEBEHDK_00656	3.25e-107	-	-	-	D	-	-	-	Capsular exopolysaccharide family
NIEBEHDK_00657	1.7e-221	-	-	-	S	-	-	-	EpsG family
NIEBEHDK_00658	5.57e-270	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIEBEHDK_00665	1.75e-92	-	-	-	-	-	-	-	-
NIEBEHDK_00666	3.44e-48	-	-	-	K	-	-	-	Helix-turn-helix
NIEBEHDK_00668	2.51e-40	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
NIEBEHDK_00669	2.01e-135	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
NIEBEHDK_00677	1.13e-103	-	-	-	S	-	-	-	Siphovirus Gp157
NIEBEHDK_00678	2.13e-167	-	-	-	S	-	-	-	AAA domain
NIEBEHDK_00679	7.72e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
NIEBEHDK_00680	6.61e-142	-	-	-	S	-	-	-	calcium ion binding
NIEBEHDK_00681	2.81e-297	-	-	-	S	-	-	-	DNA helicase activity
NIEBEHDK_00683	5.56e-72	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
NIEBEHDK_00684	1.63e-34	-	-	-	-	-	-	-	-
NIEBEHDK_00685	2.22e-34	-	-	-	-	-	-	-	-
NIEBEHDK_00686	1.93e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
NIEBEHDK_00688	7.15e-44	-	-	-	-	-	-	-	-
NIEBEHDK_00689	3.98e-54	-	-	-	S	-	-	-	YopX protein
NIEBEHDK_00691	4.4e-101	-	-	-	-	-	-	-	-
NIEBEHDK_00693	0.000459	-	-	-	S	-	-	-	CsbD-like
NIEBEHDK_00694	1.04e-66	-	-	-	-	-	-	-	-
NIEBEHDK_00696	1.23e-90	-	-	-	L	-	-	-	HNH nucleases
NIEBEHDK_00697	4.9e-100	-	-	-	S	-	-	-	Phage terminase, small subunit
NIEBEHDK_00699	1.26e-287	-	-	-	S	-	-	-	Phage portal protein
NIEBEHDK_00700	3.83e-139	-	-	-	S	-	-	-	peptidase activity
NIEBEHDK_00701	4.01e-262	-	-	-	S	-	-	-	peptidase activity
NIEBEHDK_00702	4.67e-37	-	-	-	S	-	-	-	peptidase activity
NIEBEHDK_00703	9.69e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
NIEBEHDK_00704	4.48e-85	-	-	-	S	-	-	-	exonuclease activity
NIEBEHDK_00705	3.25e-39	-	-	-	-	-	-	-	-
NIEBEHDK_00706	2.06e-94	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
NIEBEHDK_00707	2.72e-27	-	-	-	-	-	-	-	-
NIEBEHDK_00708	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
NIEBEHDK_00709	0.0	-	-	-	S	-	-	-	Phage tail protein
NIEBEHDK_00710	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
NIEBEHDK_00711	6.88e-71	-	-	-	-	-	-	-	-
NIEBEHDK_00713	4.74e-70	-	-	-	-	-	-	-	-
NIEBEHDK_00714	6.64e-80	hol	-	-	S	-	-	-	Bacteriophage holin
NIEBEHDK_00715	2.68e-292	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NIEBEHDK_00718	1e-138	-	-	-	-	-	-	-	-
NIEBEHDK_00719	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIEBEHDK_00720	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_00721	3.41e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NIEBEHDK_00722	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NIEBEHDK_00723	1.25e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NIEBEHDK_00724	2.47e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NIEBEHDK_00725	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NIEBEHDK_00726	9.24e-128	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NIEBEHDK_00727	2.1e-213	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NIEBEHDK_00728	6.61e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NIEBEHDK_00729	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NIEBEHDK_00730	2.06e-174	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIEBEHDK_00731	9.29e-123	-	-	-	F	-	-	-	NUDIX domain
NIEBEHDK_00733	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NIEBEHDK_00734	1.49e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NIEBEHDK_00735	5.43e-281	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIEBEHDK_00736	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NIEBEHDK_00737	3.14e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NIEBEHDK_00738	1.12e-270	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NIEBEHDK_00739	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
NIEBEHDK_00740	8.17e-135	-	-	-	S	-	-	-	CYTH
NIEBEHDK_00741	1.19e-159	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NIEBEHDK_00742	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIEBEHDK_00743	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIEBEHDK_00744	3.99e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIEBEHDK_00745	1.51e-144	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NIEBEHDK_00746	1.61e-185	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIEBEHDK_00747	3.13e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NIEBEHDK_00748	7.55e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NIEBEHDK_00749	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEBEHDK_00750	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEBEHDK_00751	9.63e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NIEBEHDK_00752	9.45e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NIEBEHDK_00753	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIEBEHDK_00754	2.93e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
NIEBEHDK_00755	2.41e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
NIEBEHDK_00756	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NIEBEHDK_00757	1.23e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NIEBEHDK_00758	3.94e-309	ymfH	-	-	S	-	-	-	Peptidase M16
NIEBEHDK_00759	1.43e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NIEBEHDK_00760	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NIEBEHDK_00761	7.88e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIEBEHDK_00762	3.23e-288	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NIEBEHDK_00763	6.68e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIEBEHDK_00764	2.37e-29	-	-	-	-	-	-	-	-
NIEBEHDK_00765	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NIEBEHDK_00766	1.57e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NIEBEHDK_00767	3.04e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NIEBEHDK_00768	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NIEBEHDK_00769	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIEBEHDK_00770	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIEBEHDK_00771	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIEBEHDK_00772	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
NIEBEHDK_00773	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NIEBEHDK_00774	7.95e-251	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NIEBEHDK_00775	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NIEBEHDK_00776	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIEBEHDK_00777	5.25e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NIEBEHDK_00778	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NIEBEHDK_00779	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NIEBEHDK_00780	1.83e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEBEHDK_00781	1.75e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEBEHDK_00782	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NIEBEHDK_00783	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
NIEBEHDK_00784	7.01e-49	-	-	-	-	-	-	-	-
NIEBEHDK_00785	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NIEBEHDK_00786	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIEBEHDK_00787	2e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIEBEHDK_00788	2.56e-249	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NIEBEHDK_00789	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIEBEHDK_00790	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIEBEHDK_00791	2.18e-109	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NIEBEHDK_00792	3.28e-143	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NIEBEHDK_00793	1.21e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_00794	4.45e-105	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIEBEHDK_00795	2.3e-178	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIEBEHDK_00796	2.32e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NIEBEHDK_00797	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIEBEHDK_00798	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIEBEHDK_00799	2.98e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NIEBEHDK_00800	1.47e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NIEBEHDK_00801	8.22e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NIEBEHDK_00802	3.36e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NIEBEHDK_00803	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NIEBEHDK_00804	9.9e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIEBEHDK_00806	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NIEBEHDK_00807	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIEBEHDK_00808	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NIEBEHDK_00809	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIEBEHDK_00810	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIEBEHDK_00811	5.53e-84	-	-	-	-	-	-	-	-
NIEBEHDK_00812	5.63e-257	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NIEBEHDK_00813	8.04e-98	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NIEBEHDK_00814	1.48e-78	-	-	-	-	-	-	-	-
NIEBEHDK_00815	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NIEBEHDK_00816	3.69e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NIEBEHDK_00817	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIEBEHDK_00818	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIEBEHDK_00819	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NIEBEHDK_00820	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NIEBEHDK_00821	3.38e-149	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NIEBEHDK_00822	7.78e-66	-	-	-	-	-	-	-	-
NIEBEHDK_00824	6.97e-304	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
NIEBEHDK_00825	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIEBEHDK_00826	1.05e-186	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIEBEHDK_00827	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
NIEBEHDK_00828	2.11e-249	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_00829	7.94e-134	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
NIEBEHDK_00830	5.33e-119	-	-	-	-	-	-	-	-
NIEBEHDK_00831	4.87e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIEBEHDK_00832	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIEBEHDK_00833	6.35e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NIEBEHDK_00834	1.2e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NIEBEHDK_00835	2.96e-210	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_00836	2.05e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIEBEHDK_00837	1.62e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NIEBEHDK_00838	3.32e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NIEBEHDK_00839	2.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NIEBEHDK_00840	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NIEBEHDK_00841	4.84e-125	-	-	-	K	-	-	-	Cupin domain
NIEBEHDK_00842	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIEBEHDK_00843	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00844	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_00845	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_00846	3.85e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NIEBEHDK_00847	2.37e-79	-	-	-	-	-	-	-	-
NIEBEHDK_00849	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NIEBEHDK_00850	7.67e-152	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_00851	1.16e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_00852	1.12e-162	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NIEBEHDK_00853	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIEBEHDK_00854	2.39e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
NIEBEHDK_00855	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIEBEHDK_00856	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIEBEHDK_00857	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
NIEBEHDK_00858	1.8e-119	-	-	-	S	-	-	-	VanZ like family
NIEBEHDK_00859	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NIEBEHDK_00860	5.7e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NIEBEHDK_00861	1.91e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NIEBEHDK_00862	2e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
NIEBEHDK_00864	3.45e-63	-	-	-	-	-	-	-	-
NIEBEHDK_00865	2.14e-105	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NIEBEHDK_00866	1.84e-65	-	-	-	-	-	-	-	-
NIEBEHDK_00867	3.7e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NIEBEHDK_00868	1.58e-96	-	-	-	-	-	-	-	-
NIEBEHDK_00869	1.03e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NIEBEHDK_00870	1.34e-184	arbV	-	-	I	-	-	-	Phosphate acyltransferases
NIEBEHDK_00871	1.36e-210	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
NIEBEHDK_00872	6.11e-229	arbY	-	-	M	-	-	-	family 8
NIEBEHDK_00873	2.93e-207	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
NIEBEHDK_00874	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NIEBEHDK_00875	2.48e-274	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIEBEHDK_00876	2.32e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NIEBEHDK_00877	7.55e-58	-	-	-	-	-	-	-	-
NIEBEHDK_00878	3.27e-79	-	-	-	-	-	-	-	-
NIEBEHDK_00879	1.38e-20	-	-	-	-	-	-	-	-
NIEBEHDK_00881	4.83e-118	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NIEBEHDK_00882	2.31e-69	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NIEBEHDK_00883	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
NIEBEHDK_00886	9.4e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
NIEBEHDK_00887	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NIEBEHDK_00888	1.04e-29	-	-	-	-	-	-	-	-
NIEBEHDK_00889	1.39e-277	-	-	-	S	-	-	-	Phage portal protein
NIEBEHDK_00890	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
NIEBEHDK_00891	4.43e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NIEBEHDK_00892	1.37e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
NIEBEHDK_00893	2.3e-23	-	-	-	-	-	-	-	-
NIEBEHDK_00894	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
NIEBEHDK_00895	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIEBEHDK_00897	1.55e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
NIEBEHDK_00898	3.15e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NIEBEHDK_00899	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NIEBEHDK_00900	1.9e-121	-	-	-	S	-	-	-	acetyltransferase
NIEBEHDK_00901	2.21e-42	-	-	-	-	-	-	-	-
NIEBEHDK_00902	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
NIEBEHDK_00903	1.84e-77	-	-	-	-	-	-	-	-
NIEBEHDK_00904	1.41e-77	-	-	-	-	-	-	-	-
NIEBEHDK_00905	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
NIEBEHDK_00907	2.46e-255	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NIEBEHDK_00908	2.4e-163	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
NIEBEHDK_00909	1.3e-51	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
NIEBEHDK_00910	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NIEBEHDK_00911	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIEBEHDK_00912	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
NIEBEHDK_00913	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEBEHDK_00914	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIEBEHDK_00915	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEBEHDK_00916	1.42e-247	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NIEBEHDK_00917	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEBEHDK_00918	8.36e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_00919	8.04e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIEBEHDK_00920	2.97e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NIEBEHDK_00921	2.23e-179	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NIEBEHDK_00922	1.53e-266	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NIEBEHDK_00923	7.53e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00924	7.88e-211	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NIEBEHDK_00925	1.95e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NIEBEHDK_00926	1.05e-40	-	-	-	-	-	-	-	-
NIEBEHDK_00927	1.28e-171	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NIEBEHDK_00928	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NIEBEHDK_00929	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NIEBEHDK_00930	1.14e-228	mocA	-	-	S	-	-	-	Oxidoreductase
NIEBEHDK_00931	5.1e-301	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NIEBEHDK_00932	2.05e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_00933	1.1e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NIEBEHDK_00935	5.65e-07	-	-	-	-	-	-	-	-
NIEBEHDK_00936	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NIEBEHDK_00937	1.35e-304	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NIEBEHDK_00938	6.98e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_00940	6.23e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEBEHDK_00941	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NIEBEHDK_00942	1.82e-229	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NIEBEHDK_00943	1.29e-76	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NIEBEHDK_00944	2.34e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NIEBEHDK_00945	9.28e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_00947	2.12e-40	-	-	-	-	-	-	-	-
NIEBEHDK_00948	6.33e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NIEBEHDK_00949	1.53e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NIEBEHDK_00950	1.89e-150	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
NIEBEHDK_00951	2.08e-58	-	-	-	M	-	-	-	Glycosyl transferase family 8
NIEBEHDK_00952	1.26e-09	nss	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NIEBEHDK_00953	5.77e-12	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NIEBEHDK_00954	6.77e-268	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIEBEHDK_00955	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_00956	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_00957	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
NIEBEHDK_00958	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIEBEHDK_00959	3.76e-107	-	-	-	S	-	-	-	Fic/DOC family
NIEBEHDK_00960	4.96e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NIEBEHDK_00961	5.01e-142	-	-	-	-	-	-	-	-
NIEBEHDK_00962	2.84e-215	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
NIEBEHDK_00963	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NIEBEHDK_00964	1.73e-35	-	-	-	T	-	-	-	PFAM SpoVT AbrB
NIEBEHDK_00965	2.8e-105	yvbK	-	-	K	-	-	-	GNAT family
NIEBEHDK_00966	1.84e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NIEBEHDK_00967	7.6e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIEBEHDK_00968	1.87e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NIEBEHDK_00969	2.43e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIEBEHDK_00970	1.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIEBEHDK_00972	1.8e-134	-	-	-	-	-	-	-	-
NIEBEHDK_00973	1.37e-165	-	-	-	-	-	-	-	-
NIEBEHDK_00974	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEBEHDK_00975	3.74e-142	vanZ	-	-	V	-	-	-	VanZ like family
NIEBEHDK_00976	5.43e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NIEBEHDK_00977	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NIEBEHDK_00979	7.12e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NIEBEHDK_00980	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NIEBEHDK_00981	7.92e-102	-	-	-	S	-	-	-	Pfam Transposase IS66
NIEBEHDK_00982	6.51e-293	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
NIEBEHDK_00983	3.12e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
NIEBEHDK_00984	4e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
NIEBEHDK_00991	2.47e-308	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
NIEBEHDK_00992	4.38e-56	-	-	-	-	-	-	-	-
NIEBEHDK_00993	2.75e-123	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NIEBEHDK_00994	1.36e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_00995	3.69e-135	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NIEBEHDK_00996	7.63e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NIEBEHDK_00997	4.82e-83	ORF00048	-	-	-	-	-	-	-
NIEBEHDK_00998	5e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NIEBEHDK_00999	5.54e-214	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_01000	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NIEBEHDK_01001	9.85e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NIEBEHDK_01002	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01003	6.02e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NIEBEHDK_01004	2.15e-237	-	-	-	K	-	-	-	Helix-turn-helix domain
NIEBEHDK_01005	6.17e-203	-	-	-	S	-	-	-	Alpha beta hydrolase
NIEBEHDK_01006	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
NIEBEHDK_01007	1.49e-164	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_01009	1.9e-193	-	-	-	-	-	-	-	-
NIEBEHDK_01010	7.16e-113	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_01011	2.84e-207	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NIEBEHDK_01012	2.66e-248	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NIEBEHDK_01013	5.22e-65	-	-	-	-	-	-	-	-
NIEBEHDK_01014	3.48e-219	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NIEBEHDK_01015	5.52e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIEBEHDK_01016	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NIEBEHDK_01017	6.2e-48	-	-	-	-	-	-	-	-
NIEBEHDK_01018	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_01019	5.01e-299	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
NIEBEHDK_01020	1.47e-43	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
NIEBEHDK_01021	1.87e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NIEBEHDK_01022	1.04e-175	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
NIEBEHDK_01023	3e-154	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
NIEBEHDK_01024	4.47e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01026	0.0	-	-	-	M	-	-	-	LysM domain
NIEBEHDK_01028	8.09e-65	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
NIEBEHDK_01029	1.55e-117	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
NIEBEHDK_01030	1.29e-44	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NIEBEHDK_01032	9.36e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NIEBEHDK_01038	5.86e-16	-	-	-	M	-	-	-	LysM domain
NIEBEHDK_01039	1.85e-67	-	-	-	-	-	-	-	-
NIEBEHDK_01040	9.19e-96	-	-	-	K	-	-	-	Putative DNA-binding domain
NIEBEHDK_01042	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
NIEBEHDK_01043	1.38e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_01044	1.38e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_01045	2.01e-141	-	-	-	-	-	-	-	-
NIEBEHDK_01046	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
NIEBEHDK_01047	5.85e-171	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
NIEBEHDK_01048	1.18e-170	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NIEBEHDK_01049	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NIEBEHDK_01050	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_01051	2.25e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NIEBEHDK_01052	3.1e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NIEBEHDK_01053	6.5e-71	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_01054	1.54e-130	-	-	-	-	-	-	-	-
NIEBEHDK_01055	9.83e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NIEBEHDK_01056	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NIEBEHDK_01057	1.06e-167	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NIEBEHDK_01058	5.82e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEBEHDK_01059	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_01060	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NIEBEHDK_01061	1.15e-207	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIEBEHDK_01062	3.36e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIEBEHDK_01063	8.73e-150	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_01064	8.13e-61	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_01065	2.22e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_01066	8.42e-149	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
NIEBEHDK_01067	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NIEBEHDK_01068	2.45e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
NIEBEHDK_01069	3.8e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NIEBEHDK_01070	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
NIEBEHDK_01071	4.3e-170	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NIEBEHDK_01072	5.51e-154	epsB	-	-	M	-	-	-	biosynthesis protein
NIEBEHDK_01073	6.21e-137	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NIEBEHDK_01074	9.5e-23	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NIEBEHDK_01076	2.39e-25	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NIEBEHDK_01077	1.85e-61	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NIEBEHDK_01078	1.29e-53	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_01080	2.05e-34	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_01081	2.15e-48	-	-	-	GM	ko:K19431	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
NIEBEHDK_01082	1.49e-96	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	COG0438 Glycosyltransferase
NIEBEHDK_01083	4.72e-67	capM	-	-	M	ko:K13012	-	ko00000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NIEBEHDK_01084	1.12e-189	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_01085	5.62e-191	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NIEBEHDK_01086	1.64e-176	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_01087	1.65e-102	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_01088	2.14e-81	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_01089	6.9e-168	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NIEBEHDK_01090	2.81e-209	-	-	-	K	-	-	-	sugar-binding domain protein
NIEBEHDK_01091	8.47e-304	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NIEBEHDK_01092	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_01093	2.62e-198	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_01094	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01095	1.77e-198	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01096	7.36e-159	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NIEBEHDK_01097	1.96e-117	fabG10	1.1.1.100, 1.3.1.28	-	IQ	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NIEBEHDK_01098	4.02e-223	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NIEBEHDK_01099	8.81e-49	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NIEBEHDK_01100	6.49e-111	-	-	-	G	-	-	-	DeoC/LacD family aldolase
NIEBEHDK_01101	7.44e-153	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NIEBEHDK_01103	3.88e-271	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
NIEBEHDK_01104	7.6e-199	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NIEBEHDK_01105	1.1e-112	-	-	-	S	-	-	-	Zeta toxin
NIEBEHDK_01106	6.56e-192	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_01107	4.79e-63	-	-	-	-	-	-	-	-
NIEBEHDK_01108	1.38e-225	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01109	4.13e-31	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01110	1.27e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01111	4.09e-202	-	-	-	GKT	-	-	-	transcriptional antiterminator
NIEBEHDK_01112	4.94e-40	-	-	-	-	-	-	-	-
NIEBEHDK_01113	7.11e-135	-	-	-	-	-	-	-	-
NIEBEHDK_01114	2.77e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NIEBEHDK_01115	6.17e-177	-	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01116	4.33e-98	-	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01117	5.52e-121	-	-	-	-	-	-	-	-
NIEBEHDK_01118	7.7e-79	-	-	-	-	-	-	-	-
NIEBEHDK_01119	1.54e-103	-	-	-	-	-	-	-	-
NIEBEHDK_01120	9.81e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NIEBEHDK_01121	3.66e-67	-	-	-	-	-	-	-	-
NIEBEHDK_01122	5.72e-29	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
NIEBEHDK_01123	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
NIEBEHDK_01124	8.27e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NIEBEHDK_01129	1.01e-14	-	-	-	-	-	-	-	-
NIEBEHDK_01130	7.81e-88	-	-	-	-	-	-	-	-
NIEBEHDK_01131	1.22e-220	ccpB	-	-	K	-	-	-	lacI family
NIEBEHDK_01132	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NIEBEHDK_01133	1.62e-199	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEBEHDK_01134	4.57e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIEBEHDK_01135	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIEBEHDK_01136	1.04e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NIEBEHDK_01137	5.9e-193	-	-	-	K	-	-	-	acetyltransferase
NIEBEHDK_01138	2.4e-117	-	-	-	-	-	-	-	-
NIEBEHDK_01139	1.03e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
NIEBEHDK_01140	4.55e-315	-	-	-	-	-	-	-	-
NIEBEHDK_01141	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NIEBEHDK_01142	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIEBEHDK_01143	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NIEBEHDK_01144	4.45e-122	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_01145	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIEBEHDK_01146	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIEBEHDK_01147	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NIEBEHDK_01148	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NIEBEHDK_01149	5.42e-117	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
NIEBEHDK_01150	5.8e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
NIEBEHDK_01151	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NIEBEHDK_01152	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
NIEBEHDK_01153	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
NIEBEHDK_01154	1.64e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIEBEHDK_01155	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NIEBEHDK_01156	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIEBEHDK_01157	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NIEBEHDK_01158	2.18e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NIEBEHDK_01159	7.19e-209	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NIEBEHDK_01161	3.78e-248	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIEBEHDK_01162	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIEBEHDK_01163	4.61e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NIEBEHDK_01164	5.92e-142	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIEBEHDK_01165	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEBEHDK_01166	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEBEHDK_01167	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NIEBEHDK_01168	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIEBEHDK_01169	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
NIEBEHDK_01170	3.94e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NIEBEHDK_01171	2.88e-197	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NIEBEHDK_01172	9.88e-55	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NIEBEHDK_01173	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
NIEBEHDK_01174	5.18e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01175	5.58e-221	-	-	-	T	-	-	-	Histidine kinase-like ATPases
NIEBEHDK_01176	1.24e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NIEBEHDK_01177	2.13e-277	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NIEBEHDK_01178	7.37e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_01179	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_01180	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
NIEBEHDK_01181	3.82e-187	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
NIEBEHDK_01182	4.53e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIEBEHDK_01183	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NIEBEHDK_01184	4.81e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIEBEHDK_01185	7.25e-156	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIEBEHDK_01186	1.38e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NIEBEHDK_01187	1.15e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIEBEHDK_01188	9.96e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NIEBEHDK_01189	1.25e-88	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIEBEHDK_01190	7.05e-176	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIEBEHDK_01191	1.34e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NIEBEHDK_01192	4.47e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NIEBEHDK_01193	4.68e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
NIEBEHDK_01194	1.56e-119	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NIEBEHDK_01195	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
NIEBEHDK_01197	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NIEBEHDK_01198	1.43e-67	-	-	-	S	-	-	-	MazG-like family
NIEBEHDK_01199	3.31e-246	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NIEBEHDK_01200	2.58e-171	-	-	-	-	-	-	-	-
NIEBEHDK_01201	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIEBEHDK_01202	5.39e-32	-	-	-	S	-	-	-	Short C-terminal domain
NIEBEHDK_01203	1.61e-274	yqiG	-	-	C	-	-	-	Oxidoreductase
NIEBEHDK_01204	1.81e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NIEBEHDK_01205	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
NIEBEHDK_01206	5.35e-70	-	-	-	S	-	-	-	Enterocin A Immunity
NIEBEHDK_01207	1.05e-70	-	-	-	-	-	-	-	-
NIEBEHDK_01208	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NIEBEHDK_01209	3.91e-24	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_01210	3.04e-44	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_01211	8.4e-170	-	-	-	S	-	-	-	CAAX protease self-immunity
NIEBEHDK_01215	1.59e-30	-	-	-	-	-	-	-	-
NIEBEHDK_01216	1.3e-59	-	-	-	S	-	-	-	Enterocin A Immunity
NIEBEHDK_01217	1.58e-170	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NIEBEHDK_01218	5.99e-287	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIEBEHDK_01220	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NIEBEHDK_01221	3.87e-301	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
NIEBEHDK_01222	5.9e-78	-	-	-	-	-	-	-	-
NIEBEHDK_01223	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NIEBEHDK_01224	1.07e-237	tas	-	-	C	-	-	-	Aldo/keto reductase family
NIEBEHDK_01225	1.23e-58	-	-	-	S	-	-	-	Enterocin A Immunity
NIEBEHDK_01226	1.93e-170	-	-	-	-	-	-	-	-
NIEBEHDK_01227	5.59e-176	-	-	-	-	-	-	-	-
NIEBEHDK_01228	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NIEBEHDK_01229	2.1e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01230	4.88e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
NIEBEHDK_01231	4.38e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NIEBEHDK_01232	4.45e-133	-	-	-	-	-	-	-	-
NIEBEHDK_01233	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01234	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01235	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
NIEBEHDK_01236	1.16e-179	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIEBEHDK_01240	1.56e-25	-	-	-	-	-	-	-	-
NIEBEHDK_01241	8e-247	yttB	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01242	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIEBEHDK_01247	3.56e-168	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
NIEBEHDK_01248	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_01249	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01250	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIEBEHDK_01251	1.02e-178	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NIEBEHDK_01252	5.54e-210	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NIEBEHDK_01253	2.09e-244	ampC	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_01254	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NIEBEHDK_01255	8.22e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NIEBEHDK_01256	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIEBEHDK_01257	1.63e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIEBEHDK_01258	7.03e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIEBEHDK_01259	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIEBEHDK_01260	8.75e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIEBEHDK_01261	4.11e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NIEBEHDK_01262	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEBEHDK_01263	8.51e-72	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIEBEHDK_01264	4.59e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEBEHDK_01265	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIEBEHDK_01266	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIEBEHDK_01268	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIEBEHDK_01269	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NIEBEHDK_01270	5.78e-19	-	-	-	-	-	-	-	-
NIEBEHDK_01271	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NIEBEHDK_01272	2.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NIEBEHDK_01273	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NIEBEHDK_01274	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NIEBEHDK_01275	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NIEBEHDK_01276	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NIEBEHDK_01277	1.41e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NIEBEHDK_01278	1.63e-266	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NIEBEHDK_01279	1.56e-189	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NIEBEHDK_01280	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIEBEHDK_01281	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
NIEBEHDK_01282	2.56e-231	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NIEBEHDK_01283	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NIEBEHDK_01284	2.9e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NIEBEHDK_01285	6.98e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIEBEHDK_01286	7.58e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NIEBEHDK_01287	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIEBEHDK_01288	2.83e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIEBEHDK_01289	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
NIEBEHDK_01290	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIEBEHDK_01291	3.84e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NIEBEHDK_01292	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NIEBEHDK_01293	4.32e-148	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NIEBEHDK_01294	9.91e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
NIEBEHDK_01295	1.84e-161	-	-	-	-	-	-	-	-
NIEBEHDK_01296	1.3e-201	dkgB	-	-	S	-	-	-	reductase
NIEBEHDK_01297	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NIEBEHDK_01298	2.81e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NIEBEHDK_01299	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_01300	5.26e-155	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
NIEBEHDK_01301	2.39e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIEBEHDK_01302	5.61e-120	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIEBEHDK_01303	1.03e-77	-	-	-	-	-	-	-	-
NIEBEHDK_01304	3.53e-227	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NIEBEHDK_01305	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NIEBEHDK_01306	1.05e-71	-	-	-	-	-	-	-	-
NIEBEHDK_01307	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NIEBEHDK_01308	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
NIEBEHDK_01309	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_01310	6.46e-218	-	-	-	K	-	-	-	sequence-specific DNA binding
NIEBEHDK_01311	2.95e-123	-	-	-	-	-	-	-	-
NIEBEHDK_01312	2.21e-110	queT	-	-	S	-	-	-	QueT transporter
NIEBEHDK_01313	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
NIEBEHDK_01314	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NIEBEHDK_01315	1.69e-167	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NIEBEHDK_01316	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
NIEBEHDK_01317	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
NIEBEHDK_01318	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
NIEBEHDK_01319	2.6e-124	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NIEBEHDK_01320	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NIEBEHDK_01321	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NIEBEHDK_01322	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIEBEHDK_01323	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIEBEHDK_01324	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NIEBEHDK_01325	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
NIEBEHDK_01326	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
NIEBEHDK_01327	8.3e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NIEBEHDK_01328	9.66e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIEBEHDK_01329	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NIEBEHDK_01330	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIEBEHDK_01331	4.9e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIEBEHDK_01332	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIEBEHDK_01333	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NIEBEHDK_01334	4.56e-214	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
NIEBEHDK_01335	1.34e-130	-	-	-	-	-	-	-	-
NIEBEHDK_01336	4.37e-240	yddH	-	-	M	-	-	-	NlpC/P60 family
NIEBEHDK_01337	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NIEBEHDK_01338	0.0	-	-	-	S	-	-	-	AAA-like domain
NIEBEHDK_01339	1.4e-90	-	-	-	S	-	-	-	TcpE family
NIEBEHDK_01340	1.66e-116	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
NIEBEHDK_01341	1.84e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIEBEHDK_01342	1.87e-107	-	-	-	L	-	-	-	DNA methylase
NIEBEHDK_01343	5.1e-72	-	-	-	-	-	-	-	-
NIEBEHDK_01344	9.83e-293	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
NIEBEHDK_01348	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NIEBEHDK_01353	9.96e-82	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NIEBEHDK_01354	4.02e-69	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NIEBEHDK_01355	3.36e-42	-	-	-	-	-	-	-	-
NIEBEHDK_01356	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01357	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01358	2.69e-95	-	-	-	-	-	-	-	-
NIEBEHDK_01359	4.49e-159	-	-	-	-	-	-	-	-
NIEBEHDK_01360	1.11e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
NIEBEHDK_01361	1.77e-189	-	-	-	-	-	-	-	-
NIEBEHDK_01362	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIEBEHDK_01363	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIEBEHDK_01364	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIEBEHDK_01365	2.9e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIEBEHDK_01366	5.46e-51	-	-	-	-	-	-	-	-
NIEBEHDK_01367	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NIEBEHDK_01368	1.67e-62	-	-	-	-	-	-	-	-
NIEBEHDK_01371	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01372	1.39e-174	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
NIEBEHDK_01373	3.89e-203	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NIEBEHDK_01374	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01375	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_01376	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NIEBEHDK_01377	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NIEBEHDK_01378	1.7e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEBEHDK_01379	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NIEBEHDK_01380	9.43e-73	-	-	-	-	-	-	-	-
NIEBEHDK_01381	4.92e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NIEBEHDK_01382	4.28e-148	-	-	-	L	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_01383	1.39e-168	-	-	-	L	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_01385	3.3e-240	ynjC	-	-	S	-	-	-	Cell surface protein
NIEBEHDK_01386	8.2e-177	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_01388	0.0	-	-	-	-	-	-	-	-
NIEBEHDK_01389	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIEBEHDK_01390	4.75e-57	-	-	-	-	-	-	-	-
NIEBEHDK_01391	2.25e-239	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIEBEHDK_01392	3.44e-70	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
NIEBEHDK_01393	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NIEBEHDK_01394	2.83e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
NIEBEHDK_01395	1.17e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NIEBEHDK_01396	9.23e-55	-	-	-	-	-	-	-	-
NIEBEHDK_01397	3.38e-169	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
NIEBEHDK_01398	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_01399	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_01400	3.35e-111	-	-	-	-	-	-	-	-
NIEBEHDK_01401	1.99e-69	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_01402	4.97e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01403	6.21e-241	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEBEHDK_01404	6.05e-118	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
NIEBEHDK_01405	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NIEBEHDK_01406	5.65e-255	yclK	-	-	T	-	-	-	Histidine kinase
NIEBEHDK_01407	4.54e-111	-	-	-	-	-	-	-	-
NIEBEHDK_01408	7.29e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_01409	1.05e-143	-	-	-	-	-	-	-	-
NIEBEHDK_01410	1.06e-53	-	-	-	-	-	-	-	-
NIEBEHDK_01411	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NIEBEHDK_01412	2.67e-56	-	-	-	-	-	-	-	-
NIEBEHDK_01413	2.16e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NIEBEHDK_01414	2e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
NIEBEHDK_01415	2.48e-142	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
NIEBEHDK_01416	3.4e-64	-	-	-	-	-	-	-	-
NIEBEHDK_01417	1.43e-38	-	-	-	-	-	-	-	-
NIEBEHDK_01418	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NIEBEHDK_01419	3.78e-131	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIEBEHDK_01420	5.45e-154	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_01421	6.52e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NIEBEHDK_01422	1.34e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01423	7.11e-260	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_01424	4.21e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NIEBEHDK_01425	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_01426	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIEBEHDK_01427	2.94e-264	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
NIEBEHDK_01428	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_01429	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01430	8.13e-137	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NIEBEHDK_01431	6.9e-200	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NIEBEHDK_01432	8.98e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
NIEBEHDK_01433	8.75e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIEBEHDK_01434	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_01435	3.05e-282	-	-	-	-	-	-	-	-
NIEBEHDK_01436	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NIEBEHDK_01437	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NIEBEHDK_01438	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NIEBEHDK_01439	3.17e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01440	4.01e-99	-	-	-	P	-	-	-	ABC-2 family transporter protein
NIEBEHDK_01441	3.71e-68	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NIEBEHDK_01442	1.95e-78	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
NIEBEHDK_01443	2.4e-137	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NIEBEHDK_01444	2.24e-64	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NIEBEHDK_01446	1.63e-192	-	-	-	EG	-	-	-	EamA-like transporter family
NIEBEHDK_01447	2.62e-95	-	-	-	L	-	-	-	NUDIX domain
NIEBEHDK_01448	8.13e-82	-	-	-	-	-	-	-	-
NIEBEHDK_01449	5.83e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIEBEHDK_01450	5.72e-238	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIEBEHDK_01451	1.13e-153	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NIEBEHDK_01452	1.94e-99	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NIEBEHDK_01453	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIEBEHDK_01454	1.03e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIEBEHDK_01455	6.84e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIEBEHDK_01456	3.74e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIEBEHDK_01457	1.18e-174	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIEBEHDK_01458	2.26e-136	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
NIEBEHDK_01460	5.06e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_01461	2.35e-136	-	-	-	-	-	-	-	-
NIEBEHDK_01462	4.03e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
NIEBEHDK_01463	8.18e-151	-	-	-	-	-	-	-	-
NIEBEHDK_01464	6.02e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_01465	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01467	6.58e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIEBEHDK_01468	1.72e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NIEBEHDK_01469	2.84e-136	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NIEBEHDK_01470	7.93e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIEBEHDK_01471	2.89e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIEBEHDK_01473	5.67e-200	bglK_1	-	-	GK	-	-	-	ROK family
NIEBEHDK_01474	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_01475	1.01e-179	-	-	-	K	-	-	-	SIS domain
NIEBEHDK_01476	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
NIEBEHDK_01477	1.99e-104	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01478	0.0	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01479	2.81e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIEBEHDK_01481	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
NIEBEHDK_01482	6.78e-132	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NIEBEHDK_01483	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
NIEBEHDK_01484	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_01485	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01486	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_01487	1.96e-225	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIEBEHDK_01488	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIEBEHDK_01490	8.07e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
NIEBEHDK_01491	5.88e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
NIEBEHDK_01492	1.3e-89	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
NIEBEHDK_01493	1.21e-309	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NIEBEHDK_01494	2.75e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NIEBEHDK_01495	3.73e-137	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
NIEBEHDK_01496	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
NIEBEHDK_01498	9.32e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_01499	2.81e-279	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
NIEBEHDK_01500	1e-306	-	-	-	EGP	-	-	-	Major Facilitator
NIEBEHDK_01501	6.82e-52	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
NIEBEHDK_01502	9.4e-76	ps105	-	-	-	-	-	-	-
NIEBEHDK_01503	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
NIEBEHDK_01504	1.74e-242	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_01505	1.9e-163	kdgR	-	-	K	-	-	-	FCD domain
NIEBEHDK_01506	6.58e-293	-	-	-	G	-	-	-	Major Facilitator
NIEBEHDK_01507	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
NIEBEHDK_01508	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
NIEBEHDK_01509	4.1e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NIEBEHDK_01510	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NIEBEHDK_01511	6.08e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_01512	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NIEBEHDK_01513	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
NIEBEHDK_01514	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
NIEBEHDK_01515	2.5e-104	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
NIEBEHDK_01516	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NIEBEHDK_01517	6.53e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
NIEBEHDK_01518	5.33e-300	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NIEBEHDK_01520	5.38e-68	-	-	-	-	-	-	-	-
NIEBEHDK_01521	3.12e-111	-	-	-	-	-	-	-	-
NIEBEHDK_01522	1.7e-142	-	-	-	S	-	-	-	Membrane
NIEBEHDK_01523	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIEBEHDK_01525	7.34e-72	-	-	-	-	-	-	-	-
NIEBEHDK_01526	1.86e-146	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NIEBEHDK_01527	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NIEBEHDK_01528	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NIEBEHDK_01529	2.32e-60	-	-	-	-	-	-	-	-
NIEBEHDK_01530	2.94e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIEBEHDK_01531	6.57e-125	-	-	-	K	-	-	-	transcriptional regulator
NIEBEHDK_01532	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01533	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_01534	3.23e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
NIEBEHDK_01535	1.37e-269	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NIEBEHDK_01536	9.89e-243	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NIEBEHDK_01537	9.5e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_01538	1.95e-107	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
NIEBEHDK_01539	7.49e-138	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIEBEHDK_01540	7.17e-39	-	-	-	-	-	-	-	-
NIEBEHDK_01541	2.05e-233	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
NIEBEHDK_01542	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
NIEBEHDK_01543	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NIEBEHDK_01544	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIEBEHDK_01545	4.51e-127	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIEBEHDK_01546	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NIEBEHDK_01547	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NIEBEHDK_01548	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIEBEHDK_01552	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NIEBEHDK_01553	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEBEHDK_01554	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEBEHDK_01555	3.29e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIEBEHDK_01556	2.87e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NIEBEHDK_01558	4.16e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIEBEHDK_01559	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIEBEHDK_01560	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NIEBEHDK_01563	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIEBEHDK_01564	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEBEHDK_01565	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NIEBEHDK_01566	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIEBEHDK_01567	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIEBEHDK_01568	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NIEBEHDK_01569	6.61e-41	-	-	-	-	-	-	-	-
NIEBEHDK_01571	3.65e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
NIEBEHDK_01572	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NIEBEHDK_01573	2.84e-284	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
NIEBEHDK_01576	4.1e-251	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
NIEBEHDK_01577	1.22e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_01580	9e-191	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NIEBEHDK_01581	5.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NIEBEHDK_01582	1.58e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIEBEHDK_01583	1.31e-84	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NIEBEHDK_01584	4.64e-217	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NIEBEHDK_01585	3.33e-84	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NIEBEHDK_01586	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
NIEBEHDK_01587	4.23e-237	-	-	-	-	-	-	-	-
NIEBEHDK_01588	8.61e-39	-	-	-	-	-	-	-	-
NIEBEHDK_01589	3.85e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01590	4.41e-113	-	-	-	C	-	-	-	nadph quinone reductase
NIEBEHDK_01591	3.88e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NIEBEHDK_01592	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_01593	1.77e-194	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIEBEHDK_01594	2.08e-283	-	-	-	K	-	-	-	IrrE N-terminal-like domain
NIEBEHDK_01595	1.23e-175	-	-	-	-	-	-	-	-
NIEBEHDK_01596	1.29e-25	-	-	-	-	-	-	-	-
NIEBEHDK_01597	7.2e-60	-	-	-	-	-	-	-	-
NIEBEHDK_01598	2.23e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NIEBEHDK_01599	2.92e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIEBEHDK_01600	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01601	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
NIEBEHDK_01602	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_01603	1.75e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
NIEBEHDK_01604	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
NIEBEHDK_01605	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
NIEBEHDK_01606	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEBEHDK_01608	7.89e-216	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NIEBEHDK_01609	4.52e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
NIEBEHDK_01610	3.93e-90	-	-	-	-	-	-	-	-
NIEBEHDK_01611	1.96e-192	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
NIEBEHDK_01613	3.32e-150	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEBEHDK_01614	1.43e-123	-	-	-	-	-	-	-	-
NIEBEHDK_01615	4.99e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
NIEBEHDK_01616	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
NIEBEHDK_01617	1.04e-289	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
NIEBEHDK_01618	1.12e-250	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NIEBEHDK_01621	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NIEBEHDK_01622	4.97e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
NIEBEHDK_01623	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
NIEBEHDK_01624	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function DUF58
NIEBEHDK_01625	2.85e-215	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NIEBEHDK_01626	3.53e-134	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
NIEBEHDK_01627	1.33e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NIEBEHDK_01628	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_01629	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_01630	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01631	7.03e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NIEBEHDK_01632	8.69e-183	-	-	-	S	-	-	-	AAA ATPase domain
NIEBEHDK_01633	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
NIEBEHDK_01634	8.05e-27	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NIEBEHDK_01635	9.49e-59	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NIEBEHDK_01636	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01637	1.94e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_01638	2.02e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NIEBEHDK_01639	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIEBEHDK_01640	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NIEBEHDK_01641	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NIEBEHDK_01642	2.69e-310	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NIEBEHDK_01643	1.15e-203	-	-	-	K	-	-	-	LysR substrate binding domain
NIEBEHDK_01644	1.49e-97	-	-	-	-	-	-	-	-
NIEBEHDK_01645	1.95e-94	-	-	-	K	-	-	-	Transcriptional regulator
NIEBEHDK_01646	3.16e-312	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
NIEBEHDK_01647	1.22e-165	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
NIEBEHDK_01649	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01650	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01651	4.19e-89	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01652	5.58e-156	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_01654	6.22e-211	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NIEBEHDK_01655	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
NIEBEHDK_01656	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NIEBEHDK_01657	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NIEBEHDK_01658	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
NIEBEHDK_01659	4.24e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NIEBEHDK_01660	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NIEBEHDK_01661	4.69e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NIEBEHDK_01662	6.64e-133	-	-	-	-	-	-	-	-
NIEBEHDK_01663	3.12e-110	ykuL	-	-	S	-	-	-	CBS domain
NIEBEHDK_01664	1.97e-200	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
NIEBEHDK_01665	5.04e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NIEBEHDK_01667	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIEBEHDK_01668	8.13e-104	ytxH	-	-	S	-	-	-	YtxH-like protein
NIEBEHDK_01669	1.83e-119	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
NIEBEHDK_01670	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NIEBEHDK_01671	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NIEBEHDK_01672	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
NIEBEHDK_01673	3.18e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEBEHDK_01674	1.24e-162	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NIEBEHDK_01675	1.38e-172	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIEBEHDK_01676	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NIEBEHDK_01677	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NIEBEHDK_01678	3.48e-73	-	-	-	-	-	-	-	-
NIEBEHDK_01679	2.32e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NIEBEHDK_01680	2.41e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NIEBEHDK_01681	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIEBEHDK_01682	8.64e-26	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NIEBEHDK_01683	6.72e-297	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NIEBEHDK_01684	9.92e-143	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NIEBEHDK_01685	4.68e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIEBEHDK_01686	8.78e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NIEBEHDK_01687	4.31e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NIEBEHDK_01688	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
NIEBEHDK_01689	9.5e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NIEBEHDK_01690	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIEBEHDK_01691	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
NIEBEHDK_01692	2.17e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIEBEHDK_01693	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
NIEBEHDK_01694	3.53e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NIEBEHDK_01695	1.52e-131	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIEBEHDK_01696	5.68e-162	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIEBEHDK_01697	4.08e-219	-	-	-	-	-	-	-	-
NIEBEHDK_01698	1.2e-07	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEBEHDK_01699	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIEBEHDK_01700	2.84e-258	-	-	-	-	-	-	-	-
NIEBEHDK_01701	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NIEBEHDK_01702	3.79e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIEBEHDK_01703	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NIEBEHDK_01704	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NIEBEHDK_01705	7.74e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
NIEBEHDK_01706	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIEBEHDK_01707	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NIEBEHDK_01708	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEBEHDK_01709	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NIEBEHDK_01710	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEBEHDK_01711	5.21e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIEBEHDK_01712	1.18e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NIEBEHDK_01713	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NIEBEHDK_01714	2.61e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NIEBEHDK_01715	7.42e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
NIEBEHDK_01717	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIEBEHDK_01718	4.46e-181	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NIEBEHDK_01719	3.43e-206	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIEBEHDK_01720	2.57e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NIEBEHDK_01721	2.08e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NIEBEHDK_01722	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIEBEHDK_01723	2.41e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIEBEHDK_01724	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NIEBEHDK_01725	6.01e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIEBEHDK_01726	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIEBEHDK_01727	4.01e-44	-	-	-	-	-	-	-	-
NIEBEHDK_01728	4.13e-109	-	-	-	S	-	-	-	ASCH
NIEBEHDK_01729	2.01e-81	-	-	-	-	-	-	-	-
NIEBEHDK_01730	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NIEBEHDK_01731	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIEBEHDK_01732	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIEBEHDK_01733	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
NIEBEHDK_01734	5.46e-189	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
NIEBEHDK_01735	1.07e-238	-	-	-	-	-	-	-	-
NIEBEHDK_01736	7.41e-37	-	-	-	-	-	-	-	-
NIEBEHDK_01737	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NIEBEHDK_01738	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NIEBEHDK_01739	9.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
NIEBEHDK_01740	1.31e-304	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NIEBEHDK_01741	1.02e-234	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NIEBEHDK_01742	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
NIEBEHDK_01743	1.69e-218	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NIEBEHDK_01744	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIEBEHDK_01745	5.4e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01746	0.0	-	-	-	E	-	-	-	Amino Acid
NIEBEHDK_01747	5.19e-207	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NIEBEHDK_01748	1.53e-302	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIEBEHDK_01749	1.33e-140	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
NIEBEHDK_01750	0.0	-	-	-	M	-	-	-	Sulfatase
NIEBEHDK_01751	9.53e-241	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
NIEBEHDK_01752	1.42e-132	-	-	-	-	-	-	-	-
NIEBEHDK_01753	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NIEBEHDK_01754	3.21e-204	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIEBEHDK_01755	1.2e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIEBEHDK_01756	1.92e-83	-	-	-	-	-	-	-	-
NIEBEHDK_01757	1.37e-90	-	-	-	-	-	-	-	-
NIEBEHDK_01758	4.44e-62	-	-	-	-	-	-	-	-
NIEBEHDK_01759	2.83e-202	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NIEBEHDK_01760	6.87e-162	citR	-	-	K	-	-	-	FCD
NIEBEHDK_01761	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
NIEBEHDK_01762	4.83e-131	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NIEBEHDK_01763	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NIEBEHDK_01764	2.5e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NIEBEHDK_01765	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NIEBEHDK_01766	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NIEBEHDK_01767	4.63e-07	-	-	-	-	-	-	-	-
NIEBEHDK_01768	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
NIEBEHDK_01769	1.44e-57	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
NIEBEHDK_01770	5.72e-69	-	-	-	-	-	-	-	-
NIEBEHDK_01775	5.07e-203	-	-	-	K	-	-	-	sequence-specific DNA binding
NIEBEHDK_01776	3.25e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01777	6.98e-241	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01778	2.8e-278	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NIEBEHDK_01779	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_01780	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NIEBEHDK_01781	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NIEBEHDK_01782	7.09e-18	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NIEBEHDK_01783	8.86e-43	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NIEBEHDK_01784	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NIEBEHDK_01785	2.44e-269	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NIEBEHDK_01786	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_01787	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
NIEBEHDK_01796	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NIEBEHDK_01797	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIEBEHDK_01798	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEBEHDK_01799	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEBEHDK_01800	2.84e-109	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
NIEBEHDK_01801	3.06e-44	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01802	0.0	-	-	-	M	-	-	-	domain protein
NIEBEHDK_01803	6.65e-212	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
NIEBEHDK_01804	3.78e-41	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
NIEBEHDK_01806	5.1e-31	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NIEBEHDK_01808	5.83e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NIEBEHDK_01810	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NIEBEHDK_01811	1.27e-144	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_01812	1.46e-148	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_01813	4.11e-83	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_01814	2.11e-38	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_01815	6.94e-92	xylR	-	-	GK	-	-	-	ROK family
NIEBEHDK_01816	6.21e-186	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NIEBEHDK_01817	8.69e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NIEBEHDK_01818	9.88e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIEBEHDK_01819	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_01820	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NIEBEHDK_01821	1.21e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NIEBEHDK_01822	1.39e-281	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIEBEHDK_01823	1.42e-102	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NIEBEHDK_01824	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NIEBEHDK_01826	2.14e-36	-	-	-	-	-	-	-	-
NIEBEHDK_01827	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NIEBEHDK_01828	3.54e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NIEBEHDK_01829	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIEBEHDK_01830	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
NIEBEHDK_01831	1.41e-53	-	-	-	-	-	-	-	-
NIEBEHDK_01832	4.54e-171	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_01833	6.28e-108	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_01834	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
NIEBEHDK_01835	5.46e-178	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
NIEBEHDK_01836	1.76e-174	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_01837	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIEBEHDK_01838	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NIEBEHDK_01839	8.08e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NIEBEHDK_01840	8.94e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NIEBEHDK_01841	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
NIEBEHDK_01842	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NIEBEHDK_01843	2.68e-15	-	-	-	-	-	-	-	-
NIEBEHDK_01845	2.15e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NIEBEHDK_01846	3.15e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NIEBEHDK_01847	1.62e-226	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NIEBEHDK_01848	1.09e-310	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NIEBEHDK_01849	2.04e-199	-	-	-	C	-	-	-	nadph quinone reductase
NIEBEHDK_01850	1.72e-120	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
NIEBEHDK_01851	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NIEBEHDK_01852	3.41e-144	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
NIEBEHDK_01853	5.46e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIEBEHDK_01854	7.73e-201	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_01855	5.16e-190	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NIEBEHDK_01856	1.51e-89	-	-	-	K	-	-	-	LytTr DNA-binding domain
NIEBEHDK_01857	7.8e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NIEBEHDK_01858	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NIEBEHDK_01859	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
NIEBEHDK_01860	1.14e-98	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NIEBEHDK_01861	5.29e-209	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NIEBEHDK_01862	1.02e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
NIEBEHDK_01863	1.11e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
NIEBEHDK_01864	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NIEBEHDK_01865	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
NIEBEHDK_01866	3.02e-92	-	-	-	-	-	-	-	-
NIEBEHDK_01867	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NIEBEHDK_01868	2.98e-315	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NIEBEHDK_01869	3.78e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
NIEBEHDK_01870	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NIEBEHDK_01871	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NIEBEHDK_01872	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_01873	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_01874	3.66e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NIEBEHDK_01875	2.07e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NIEBEHDK_01876	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_01877	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01878	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIEBEHDK_01879	5.32e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NIEBEHDK_01880	3.96e-187	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NIEBEHDK_01881	2.58e-101	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NIEBEHDK_01882	7.71e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_01883	0.0	-	-	-	-	-	-	-	-
NIEBEHDK_01884	1.21e-211	yicL	-	-	EG	-	-	-	EamA-like transporter family
NIEBEHDK_01885	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NIEBEHDK_01886	6.79e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_01887	2.63e-73	-	-	-	-	-	-	-	-
NIEBEHDK_01888	3.52e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_01890	1e-35	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NIEBEHDK_01891	6.41e-190	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
NIEBEHDK_01892	3.8e-61	-	-	-	-	-	-	-	-
NIEBEHDK_01893	1.18e-228	-	-	-	S	-	-	-	Cell surface protein
NIEBEHDK_01894	3.31e-98	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_01895	1.2e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NIEBEHDK_01896	2.12e-173	-	-	-	-	-	-	-	-
NIEBEHDK_01897	9.6e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_01898	1.61e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NIEBEHDK_01899	1.94e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NIEBEHDK_01901	2.58e-179	-	-	-	-	-	-	-	-
NIEBEHDK_01903	8.14e-156	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NIEBEHDK_01904	9.58e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NIEBEHDK_01905	4.03e-104	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NIEBEHDK_01906	2.09e-302	xylP	-	-	G	-	-	-	MFS/sugar transport protein
NIEBEHDK_01907	0.0	ycaM	-	-	E	-	-	-	amino acid
NIEBEHDK_01908	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NIEBEHDK_01909	8.65e-136	-	-	-	-	-	-	-	-
NIEBEHDK_01910	7.35e-252	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NIEBEHDK_01911	8.79e-208	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NIEBEHDK_01912	7.75e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIEBEHDK_01913	1.98e-163	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NIEBEHDK_01914	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIEBEHDK_01915	2.47e-166	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_01916	1e-251	-	-	-	-	-	-	-	-
NIEBEHDK_01917	2.64e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NIEBEHDK_01918	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIEBEHDK_01919	4.95e-246	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIEBEHDK_01920	1.52e-207	-	-	-	S	-	-	-	reductase
NIEBEHDK_01921	1.82e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NIEBEHDK_01922	6.46e-290	-	-	-	E	-	-	-	Amino acid permease
NIEBEHDK_01923	5.06e-282	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
NIEBEHDK_01924	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
NIEBEHDK_01925	2.96e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_01926	6.71e-135	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NIEBEHDK_01927	3.54e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NIEBEHDK_01928	1.29e-177	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
NIEBEHDK_01929	2.26e-245	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NIEBEHDK_01930	9.62e-78	pbpE	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_01931	1.64e-121	pbpE	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_01932	5.86e-61	-	-	-	-	-	-	-	-
NIEBEHDK_01933	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NIEBEHDK_01934	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NIEBEHDK_01935	4.01e-44	-	-	-	-	-	-	-	-
NIEBEHDK_01937	8.67e-276	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NIEBEHDK_01938	6.12e-97	-	-	-	L	-	-	-	Resolvase, N-terminal
NIEBEHDK_01939	2.19e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NIEBEHDK_01940	8.1e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
NIEBEHDK_01941	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
NIEBEHDK_01942	1.52e-39	-	-	-	-	-	-	-	-
NIEBEHDK_01943	1.27e-37	-	-	-	L	-	-	-	RelB antitoxin
NIEBEHDK_01944	0.0	-	-	-	L	-	-	-	Exonuclease
NIEBEHDK_01948	2.52e-16	-	-	-	-	-	-	-	-
NIEBEHDK_01949	1.75e-100	-	-	-	O	-	-	-	OsmC-like protein
NIEBEHDK_01950	2e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NIEBEHDK_01951	1.42e-133	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NIEBEHDK_01952	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_01953	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_01954	1.61e-24	-	-	-	-	-	-	-	-
NIEBEHDK_01955	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NIEBEHDK_01956	2.77e-222	-	-	-	-	-	-	-	-
NIEBEHDK_01957	9.29e-250	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NIEBEHDK_01958	2.12e-192	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NIEBEHDK_01963	1.35e-174	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NIEBEHDK_01964	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_01965	5.03e-80	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_01966	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NIEBEHDK_01967	3.49e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_01968	2.05e-165	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_01969	8.14e-98	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_01970	1.8e-209	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NIEBEHDK_01971	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
NIEBEHDK_01972	2.15e-193	-	-	-	S	-	-	-	hydrolase
NIEBEHDK_01973	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
NIEBEHDK_01974	1.22e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_01975	1.56e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_01976	2.54e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_01977	1.98e-186	-	-	-	M	-	-	-	hydrolase, family 25
NIEBEHDK_01978	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
NIEBEHDK_01980	1.48e-163	-	-	-	-	-	-	-	-
NIEBEHDK_01981	1.84e-73	-	-	-	C	-	-	-	nitroreductase
NIEBEHDK_01982	1.74e-15	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NIEBEHDK_01983	8.41e-244	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01984	2.4e-92	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NIEBEHDK_01985	1.67e-109	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NIEBEHDK_01986	8.83e-96	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01987	2.88e-106	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_01988	3.78e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01989	6.54e-58	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01990	6.27e-83	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NIEBEHDK_01991	8.71e-271	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01992	7.61e-240	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NIEBEHDK_01993	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_01994	2.4e-80	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_01995	4.07e-24	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NIEBEHDK_01996	2.64e-218	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NIEBEHDK_01997	8.16e-108	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
NIEBEHDK_01998	4.05e-258	-	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NIEBEHDK_01999	2.92e-248	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NIEBEHDK_02000	5.1e-144	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
NIEBEHDK_02001	3.92e-159	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
NIEBEHDK_02002	9.7e-211	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
NIEBEHDK_02003	4.75e-58	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02004	9.91e-87	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_02005	2.17e-215	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_02006	4.54e-40	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIEBEHDK_02007	8.13e-294	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
NIEBEHDK_02008	6.59e-291	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_02009	3.04e-293	bglP11	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NIEBEHDK_02010	1.74e-116	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NIEBEHDK_02011	3.75e-65	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NIEBEHDK_02012	1.01e-56	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIEBEHDK_02013	1.91e-11	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NIEBEHDK_02015	8.14e-48	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NIEBEHDK_02016	1.25e-263	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NIEBEHDK_02017	4.21e-277	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
NIEBEHDK_02018	1.66e-84	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIEBEHDK_02019	1.54e-166	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NIEBEHDK_02020	4.79e-35	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NIEBEHDK_02021	3.85e-230	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_02022	1.04e-34	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_02023	2.26e-72	gntR	-	-	K	-	-	-	rpiR family
NIEBEHDK_02024	3.94e-66	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEBEHDK_02025	1.62e-81	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_02026	4.95e-39	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_02027	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02028	2.02e-236	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
NIEBEHDK_02030	1.88e-123	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
NIEBEHDK_02031	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
NIEBEHDK_02032	1.09e-296	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_02033	3.54e-57	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_02034	4.15e-312	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NIEBEHDK_02035	6.08e-192	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIEBEHDK_02036	1.02e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NIEBEHDK_02037	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
NIEBEHDK_02038	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NIEBEHDK_02039	2.63e-203	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
NIEBEHDK_02040	3.95e-138	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
NIEBEHDK_02041	8.04e-210	-	-	-	C	-	-	-	FAD dependent oxidoreductase
NIEBEHDK_02042	2.6e-102	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NIEBEHDK_02043	0.0	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
NIEBEHDK_02046	9.23e-107	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NIEBEHDK_02047	4.45e-108	repA	-	-	S	-	-	-	Replication initiator protein A
NIEBEHDK_02052	9.85e-05	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
NIEBEHDK_02054	2.25e-284	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
NIEBEHDK_02056	4.74e-67	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NIEBEHDK_02057	3.94e-23	-	-	-	-	-	-	-	-
NIEBEHDK_02058	8.49e-12	-	-	-	-	-	-	-	-
NIEBEHDK_02059	3.27e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
NIEBEHDK_02060	7.5e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIEBEHDK_02061	1.61e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEBEHDK_02062	4.65e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NIEBEHDK_02063	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIEBEHDK_02064	3.4e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIEBEHDK_02065	3.34e-214	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NIEBEHDK_02066	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIEBEHDK_02067	4.33e-127	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NIEBEHDK_02068	1.96e-126	-	-	-	-	-	-	-	-
NIEBEHDK_02069	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NIEBEHDK_02070	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NIEBEHDK_02072	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NIEBEHDK_02073	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02074	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02075	4.36e-284	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIEBEHDK_02076	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NIEBEHDK_02077	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NIEBEHDK_02078	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIEBEHDK_02079	2.59e-55	-	-	-	-	-	-	-	-
NIEBEHDK_02080	4.69e-70	-	-	-	-	-	-	-	-
NIEBEHDK_02081	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NIEBEHDK_02082	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NIEBEHDK_02083	4.52e-54	-	-	-	S	-	-	-	Abortive infection C-terminus
NIEBEHDK_02085	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_02086	2.13e-64	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02087	4.46e-91	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_02089	5.59e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NIEBEHDK_02090	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NIEBEHDK_02091	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NIEBEHDK_02092	1.93e-203	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIEBEHDK_02093	1.64e-32	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIEBEHDK_02094	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIEBEHDK_02096	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NIEBEHDK_02097	9.87e-70	-	-	-	-	-	-	-	-
NIEBEHDK_02098	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NIEBEHDK_02099	1.89e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NIEBEHDK_02100	3.97e-23	-	-	-	-	-	-	-	-
NIEBEHDK_02101	3.33e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIEBEHDK_02102	7.62e-53	-	-	-	-	-	-	-	-
NIEBEHDK_02103	1.89e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02104	3.76e-177	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_02105	2.16e-158	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_02106	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
NIEBEHDK_02108	5.44e-147	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NIEBEHDK_02109	3.83e-61	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
NIEBEHDK_02110	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
NIEBEHDK_02111	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NIEBEHDK_02112	3.82e-255	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIEBEHDK_02113	1.1e-230	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NIEBEHDK_02114	7.65e-164	-	-	-	M	-	-	-	domain protein
NIEBEHDK_02115	4.26e-292	yvcC	-	-	M	-	-	-	Cna protein B-type domain
NIEBEHDK_02116	2.06e-312	yvcC	-	-	M	-	-	-	Cna protein B-type domain
NIEBEHDK_02117	7.65e-20	-	-	-	-	-	-	-	-
NIEBEHDK_02118	1.65e-116	-	-	-	-	-	-	-	-
NIEBEHDK_02119	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NIEBEHDK_02120	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NIEBEHDK_02122	3.57e-28	-	-	-	-	-	-	-	-
NIEBEHDK_02123	7.46e-61	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
NIEBEHDK_02125	1.24e-21	-	-	-	-	-	-	-	-
NIEBEHDK_02126	6.32e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NIEBEHDK_02127	0.0	ybeC	-	-	E	-	-	-	amino acid
NIEBEHDK_02128	2.21e-121	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
NIEBEHDK_02153	3.63e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NIEBEHDK_02154	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEBEHDK_02155	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NIEBEHDK_02156	2e-228	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIEBEHDK_02157	4.38e-222	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIEBEHDK_02158	9.07e-114	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NIEBEHDK_02159	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIEBEHDK_02160	3.43e-172	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIEBEHDK_02161	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
NIEBEHDK_02162	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NIEBEHDK_02163	7.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NIEBEHDK_02164	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NIEBEHDK_02165	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEBEHDK_02166	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIEBEHDK_02167	2.89e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NIEBEHDK_02168	9.72e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NIEBEHDK_02169	2.05e-177	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIEBEHDK_02170	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIEBEHDK_02171	1.96e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NIEBEHDK_02172	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIEBEHDK_02173	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NIEBEHDK_02174	1.29e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NIEBEHDK_02175	1.5e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NIEBEHDK_02176	4.02e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NIEBEHDK_02177	2.83e-301	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NIEBEHDK_02178	7.66e-178	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
NIEBEHDK_02179	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_02180	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_02181	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NIEBEHDK_02182	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
NIEBEHDK_02183	1.08e-35	-	-	-	-	-	-	-	-
NIEBEHDK_02184	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIEBEHDK_02185	2.14e-189	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NIEBEHDK_02186	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIEBEHDK_02187	2.2e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NIEBEHDK_02188	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NIEBEHDK_02189	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIEBEHDK_02190	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIEBEHDK_02191	1.47e-33	-	-	-	-	-	-	-	-
NIEBEHDK_02192	1.12e-69	-	-	-	-	-	-	-	-
NIEBEHDK_02193	3.16e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIEBEHDK_02194	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NIEBEHDK_02195	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIEBEHDK_02196	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NIEBEHDK_02197	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIEBEHDK_02198	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_02199	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_02200	2.99e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_02201	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIEBEHDK_02202	1.16e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIEBEHDK_02203	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIEBEHDK_02204	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NIEBEHDK_02205	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NIEBEHDK_02206	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NIEBEHDK_02207	1.1e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NIEBEHDK_02208	1.63e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NIEBEHDK_02209	2.45e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIEBEHDK_02210	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NIEBEHDK_02211	4.47e-175	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NIEBEHDK_02212	5.69e-220	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIEBEHDK_02213	3.87e-76	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIEBEHDK_02214	2.29e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIEBEHDK_02215	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIEBEHDK_02216	3.8e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIEBEHDK_02217	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIEBEHDK_02218	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NIEBEHDK_02219	4.46e-156	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
NIEBEHDK_02220	8.07e-68	-	-	-	-	-	-	-	-
NIEBEHDK_02221	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NIEBEHDK_02222	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NIEBEHDK_02223	4.68e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NIEBEHDK_02224	2.27e-186	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIEBEHDK_02225	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEBEHDK_02226	2.58e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEBEHDK_02227	9.8e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIEBEHDK_02228	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIEBEHDK_02229	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NIEBEHDK_02230	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEBEHDK_02231	1.51e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NIEBEHDK_02232	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NIEBEHDK_02233	4.18e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NIEBEHDK_02234	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NIEBEHDK_02235	5.41e-43	-	-	-	-	-	-	-	-
NIEBEHDK_02236	1.77e-20	-	-	-	-	-	-	-	-
NIEBEHDK_02237	2.69e-297	-	-	-	S	-	-	-	Membrane
NIEBEHDK_02239	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NIEBEHDK_02240	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIEBEHDK_02241	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NIEBEHDK_02242	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NIEBEHDK_02243	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NIEBEHDK_02244	6.73e-305	ynbB	-	-	P	-	-	-	aluminum resistance
NIEBEHDK_02245	3.41e-231	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIEBEHDK_02246	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NIEBEHDK_02247	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NIEBEHDK_02248	4.82e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NIEBEHDK_02249	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NIEBEHDK_02250	8.99e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NIEBEHDK_02251	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NIEBEHDK_02252	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
NIEBEHDK_02253	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NIEBEHDK_02254	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NIEBEHDK_02255	2.79e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIEBEHDK_02256	2.31e-166	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
NIEBEHDK_02257	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEBEHDK_02258	1.98e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NIEBEHDK_02259	2.75e-267	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIEBEHDK_02260	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEBEHDK_02261	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIEBEHDK_02262	1.44e-90	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIEBEHDK_02263	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEBEHDK_02264	5e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEBEHDK_02265	1.45e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NIEBEHDK_02266	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEBEHDK_02267	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIEBEHDK_02268	1.01e-157	csrR	-	-	K	-	-	-	response regulator
NIEBEHDK_02269	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIEBEHDK_02270	1.14e-122	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NIEBEHDK_02271	3.45e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NIEBEHDK_02272	1.19e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
NIEBEHDK_02273	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIEBEHDK_02274	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NIEBEHDK_02275	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIEBEHDK_02276	7.67e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NIEBEHDK_02277	9.33e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NIEBEHDK_02278	4.16e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NIEBEHDK_02279	1.31e-238	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIEBEHDK_02280	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
NIEBEHDK_02281	6.85e-228	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
NIEBEHDK_02282	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NIEBEHDK_02283	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIEBEHDK_02284	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NIEBEHDK_02285	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIEBEHDK_02286	7.83e-292	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NIEBEHDK_02287	9.99e-05	-	-	-	-	-	-	-	-
NIEBEHDK_02289	1.28e-29	-	-	-	K	-	-	-	regulation of single-species biofilm formation
NIEBEHDK_02290	1.71e-28	-	-	-	K	-	-	-	WYL domain
NIEBEHDK_02291	1.19e-160	-	-	-	S	-	-	-	SseB protein N-terminal domain
NIEBEHDK_02292	5.87e-86	-	-	-	-	-	-	-	-
NIEBEHDK_02293	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIEBEHDK_02294	3.91e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NIEBEHDK_02295	2.78e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NIEBEHDK_02296	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIEBEHDK_02297	4.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIEBEHDK_02298	5.95e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIEBEHDK_02299	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIEBEHDK_02300	1.65e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
NIEBEHDK_02301	7.54e-242	-	-	-	S	-	-	-	Cell surface protein
NIEBEHDK_02303	2.02e-174	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
NIEBEHDK_02304	0.0	-	-	-	N	-	-	-	domain, Protein
NIEBEHDK_02305	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02306	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NIEBEHDK_02307	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NIEBEHDK_02309	1.63e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEBEHDK_02310	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NIEBEHDK_02312	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIEBEHDK_02313	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
NIEBEHDK_02314	0.000128	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEBEHDK_02315	4.2e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_02316	3.79e-29	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02317	1.34e-125	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02318	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NIEBEHDK_02319	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
NIEBEHDK_02320	2.5e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEBEHDK_02321	3.48e-207	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEBEHDK_02322	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
NIEBEHDK_02323	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NIEBEHDK_02324	1.4e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NIEBEHDK_02325	2.72e-97	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NIEBEHDK_02326	9.47e-48	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NIEBEHDK_02327	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NIEBEHDK_02329	1.34e-86	-	-	-	-	-	-	-	-
NIEBEHDK_02330	1.93e-30	-	-	-	-	-	-	-	-
NIEBEHDK_02331	3.26e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
NIEBEHDK_02332	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
NIEBEHDK_02333	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIEBEHDK_02334	1.9e-72	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIEBEHDK_02335	2.31e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NIEBEHDK_02336	9.97e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NIEBEHDK_02337	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NIEBEHDK_02338	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_02339	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
NIEBEHDK_02340	2.28e-207	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NIEBEHDK_02341	2.56e-27	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NIEBEHDK_02342	1.84e-34	-	-	-	-	-	-	-	-
NIEBEHDK_02343	1.13e-81	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_02344	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
NIEBEHDK_02345	1.26e-178	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
NIEBEHDK_02346	3.08e-32	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
NIEBEHDK_02348	4.68e-184	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NIEBEHDK_02349	2.01e-102	-	-	-	-	-	-	-	-
NIEBEHDK_02351	1.65e-97	-	-	-	-	-	-	-	-
NIEBEHDK_02352	4.79e-21	-	-	-	-	-	-	-	-
NIEBEHDK_02353	6.86e-85	-	-	-	-	-	-	-	-
NIEBEHDK_02354	1.84e-211	-	-	-	-	-	-	-	-
NIEBEHDK_02355	7.81e-238	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NIEBEHDK_02356	4.21e-53	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NIEBEHDK_02357	9.34e-275	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NIEBEHDK_02358	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NIEBEHDK_02359	4.9e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NIEBEHDK_02360	3.41e-68	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NIEBEHDK_02361	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
NIEBEHDK_02363	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
NIEBEHDK_02364	9.89e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
NIEBEHDK_02365	1.4e-282	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
NIEBEHDK_02366	4.16e-120	-	-	-	-	-	-	-	-
NIEBEHDK_02367	2.97e-48	-	-	-	S	-	-	-	CD20-like family
NIEBEHDK_02368	0.000358	-	-	-	-	-	-	-	-
NIEBEHDK_02369	2.87e-60	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
NIEBEHDK_02373	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
NIEBEHDK_02374	1.45e-46	-	-	-	-	-	-	-	-
NIEBEHDK_02375	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02376	2.96e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
NIEBEHDK_02377	7.48e-49	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
NIEBEHDK_02378	7.62e-54	tnp2PF3	-	-	L	-	-	-	Transposase
NIEBEHDK_02379	1.45e-30	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02380	3.69e-73	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02381	7.39e-163	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NIEBEHDK_02382	2.33e-218	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02383	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIEBEHDK_02384	1.24e-45	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
NIEBEHDK_02385	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
NIEBEHDK_02386	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NIEBEHDK_02387	1.98e-50	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NIEBEHDK_02389	5.24e-113	-	-	-	-	-	-	-	-
NIEBEHDK_02390	2.78e-118	-	-	-	S	-	-	-	MucBP domain
NIEBEHDK_02391	2.62e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NIEBEHDK_02394	1.12e-115	-	-	-	E	-	-	-	AAA domain
NIEBEHDK_02395	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIEBEHDK_02396	3.34e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NIEBEHDK_02397	5.69e-65	-	-	-	-	-	-	-	-
NIEBEHDK_02398	8.51e-112	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIEBEHDK_02399	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEBEHDK_02400	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIEBEHDK_02401	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIEBEHDK_02402	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NIEBEHDK_02403	2.6e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIEBEHDK_02404	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NIEBEHDK_02405	2.38e-225	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NIEBEHDK_02406	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NIEBEHDK_02407	1.56e-194	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIEBEHDK_02408	2.76e-11	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NIEBEHDK_02409	4.23e-154	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NIEBEHDK_02410	8.71e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NIEBEHDK_02411	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
NIEBEHDK_02412	7.32e-153	-	-	-	-	-	-	-	-
NIEBEHDK_02413	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NIEBEHDK_02414	1.06e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NIEBEHDK_02415	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIEBEHDK_02416	6.92e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02417	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NIEBEHDK_02418	9.06e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIEBEHDK_02419	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NIEBEHDK_02420	4e-202	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_02421	3.97e-235	-	-	-	-	-	-	-	-
NIEBEHDK_02422	4.11e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NIEBEHDK_02423	8.88e-139	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIEBEHDK_02424	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIEBEHDK_02425	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIEBEHDK_02426	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NIEBEHDK_02427	0.0	ydaO	-	-	E	-	-	-	amino acid
NIEBEHDK_02428	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIEBEHDK_02429	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIEBEHDK_02430	1.43e-123	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
NIEBEHDK_02431	9.24e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NIEBEHDK_02432	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NIEBEHDK_02433	3.95e-253	-	-	-	I	-	-	-	Acyltransferase
NIEBEHDK_02434	2.21e-184	-	-	-	S	-	-	-	Alpha beta hydrolase
NIEBEHDK_02435	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NIEBEHDK_02436	1.82e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NIEBEHDK_02437	1.71e-145	-	-	-	F	-	-	-	glutamine amidotransferase
NIEBEHDK_02438	3.75e-142	-	-	-	T	-	-	-	Sh3 type 3 domain protein
NIEBEHDK_02439	5.22e-132	-	-	-	Q	-	-	-	methyltransferase
NIEBEHDK_02441	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NIEBEHDK_02442	2.11e-82	-	-	-	-	-	-	-	-
NIEBEHDK_02443	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
NIEBEHDK_02444	4.49e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NIEBEHDK_02445	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
NIEBEHDK_02446	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
NIEBEHDK_02447	5.33e-57	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NIEBEHDK_02448	1.19e-71	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NIEBEHDK_02449	2.7e-160	-	-	-	EG	-	-	-	EamA-like transporter family
NIEBEHDK_02450	1.57e-34	-	-	-	-	-	-	-	-
NIEBEHDK_02451	1.31e-09	-	-	-	-	-	-	-	-
NIEBEHDK_02452	5.73e-86	-	-	-	-	-	-	-	-
NIEBEHDK_02453	3.38e-50	-	-	-	-	-	-	-	-
NIEBEHDK_02454	8.01e-231	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIEBEHDK_02455	9.73e-249	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NIEBEHDK_02456	1.9e-33	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NIEBEHDK_02457	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NIEBEHDK_02458	4.14e-232	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NIEBEHDK_02459	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIEBEHDK_02460	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIEBEHDK_02462	1.77e-227	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NIEBEHDK_02463	6.36e-98	-	-	-	S	-	-	-	NusG domain II
NIEBEHDK_02464	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NIEBEHDK_02465	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NIEBEHDK_02466	1.99e-204	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NIEBEHDK_02467	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_02468	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NIEBEHDK_02469	1.69e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
NIEBEHDK_02470	6.91e-149	-	-	-	I	-	-	-	ABC-2 family transporter protein
NIEBEHDK_02471	7.25e-206	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_02472	1.13e-84	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NIEBEHDK_02473	1.39e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIEBEHDK_02474	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_02475	1.35e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEBEHDK_02476	4.43e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIEBEHDK_02477	4.58e-45	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NIEBEHDK_02478	5.79e-132	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NIEBEHDK_02479	4.35e-263	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIEBEHDK_02480	2.44e-06	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEBEHDK_02481	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NIEBEHDK_02482	4.41e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIEBEHDK_02483	2.91e-223	-	-	-	V	ko:K01421	-	ko00000	domain protein
NIEBEHDK_02484	2.96e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIEBEHDK_02485	1.06e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NIEBEHDK_02486	3.3e-162	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
NIEBEHDK_02487	6.61e-277	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIEBEHDK_02488	6.32e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEBEHDK_02489	1.16e-211	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NIEBEHDK_02490	6.68e-89	-	-	-	-	-	-	-	-
NIEBEHDK_02491	3.05e-269	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
NIEBEHDK_02492	1.12e-216	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NIEBEHDK_02493	1.36e-83	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NIEBEHDK_02494	7.93e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NIEBEHDK_02495	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NIEBEHDK_02496	3.54e-199	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIEBEHDK_02497	9.92e-317	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NIEBEHDK_02498	7.15e-94	usp1	-	-	T	-	-	-	Universal stress protein family
NIEBEHDK_02499	2.9e-169	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
NIEBEHDK_02500	4.36e-283	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
NIEBEHDK_02501	3.51e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NIEBEHDK_02502	2.48e-209	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NIEBEHDK_02503	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NIEBEHDK_02504	3.45e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
NIEBEHDK_02505	7.52e-80	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIEBEHDK_02506	1.57e-71	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIEBEHDK_02507	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
NIEBEHDK_02508	3.38e-252	pbpX	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_02509	1.17e-193	-	-	-	S	-	-	-	zinc-ribbon domain
NIEBEHDK_02510	1.39e-40	-	-	-	-	-	-	-	-
NIEBEHDK_02511	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEBEHDK_02512	1.63e-109	-	-	-	F	-	-	-	NUDIX domain
NIEBEHDK_02513	2.64e-134	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NIEBEHDK_02514	3.44e-236	-	-	-	-	-	-	-	-
NIEBEHDK_02515	7.01e-209	-	-	-	S	-	-	-	Putative esterase
NIEBEHDK_02516	2.95e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NIEBEHDK_02517	3.31e-89	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
NIEBEHDK_02518	9.17e-37	-	-	-	-	-	-	-	-
NIEBEHDK_02519	2.87e-92	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NIEBEHDK_02520	8.04e-205	nox	-	-	C	-	-	-	NADH oxidase
NIEBEHDK_02521	6.21e-69	-	-	-	T	-	-	-	diguanylate cyclase
NIEBEHDK_02522	5.73e-100	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NIEBEHDK_02523	9.57e-78	-	-	-	-	-	-	-	-
NIEBEHDK_02524	3.07e-99	-	-	-	S	-	-	-	Protein conserved in bacteria
NIEBEHDK_02525	1.58e-228	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
NIEBEHDK_02526	3.4e-257	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NIEBEHDK_02527	5.55e-101	-	-	-	T	-	-	-	diguanylate cyclase activity
NIEBEHDK_02528	3.16e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NIEBEHDK_02529	6.3e-82	-	-	-	P	-	-	-	Rhodanese-like domain
NIEBEHDK_02530	1.42e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
NIEBEHDK_02531	2.01e-243	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
NIEBEHDK_02532	4.29e-46	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
NIEBEHDK_02533	4.21e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NIEBEHDK_02534	1.67e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIEBEHDK_02535	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIEBEHDK_02536	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NIEBEHDK_02537	4.19e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NIEBEHDK_02538	3.37e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NIEBEHDK_02539	4.03e-283	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIEBEHDK_02540	3.52e-78	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIEBEHDK_02541	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIEBEHDK_02542	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NIEBEHDK_02543	1.45e-192	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIEBEHDK_02544	1.02e-185	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NIEBEHDK_02545	6.84e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NIEBEHDK_02546	1.58e-205	-	-	-	GM	-	-	-	NmrA-like family
NIEBEHDK_02548	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NIEBEHDK_02549	8.54e-223	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NIEBEHDK_02550	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_02551	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NIEBEHDK_02552	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
NIEBEHDK_02553	5.8e-270	-	-	-	-	-	-	-	-
NIEBEHDK_02554	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NIEBEHDK_02555	2.44e-268	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NIEBEHDK_02556	3.14e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
NIEBEHDK_02557	2.01e-213	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIEBEHDK_02558	2.71e-79	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NIEBEHDK_02559	2.76e-39	-	-	-	-	-	-	-	-
NIEBEHDK_02562	9.23e-44	-	-	-	-	-	-	-	-
NIEBEHDK_02563	5.07e-68	-	-	-	O	-	-	-	Torsin
NIEBEHDK_02565	1.51e-173	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NIEBEHDK_02567	3.2e-131	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
NIEBEHDK_02568	3.66e-36	-	-	-	V	-	-	-	MacB-like periplasmic core domain
NIEBEHDK_02569	6.62e-69	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02570	2.53e-37	-	-	-	-	-	-	-	-
NIEBEHDK_02571	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
NIEBEHDK_02572	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
NIEBEHDK_02574	1.43e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
NIEBEHDK_02575	1.19e-107	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02577	4.33e-118	-	-	-	S	-	-	-	Plasmid replication protein
NIEBEHDK_02578	3.67e-259	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
NIEBEHDK_02579	3.22e-10	-	-	-	-	-	-	-	-
NIEBEHDK_02580	1.77e-60	-	-	-	L	-	-	-	Integrase core domain
NIEBEHDK_02582	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIEBEHDK_02583	0.0	-	-	-	M	-	-	-	Right handed beta helix region
NIEBEHDK_02584	6.74e-100	-	-	-	-	-	-	-	-
NIEBEHDK_02585	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
NIEBEHDK_02586	0.000638	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NIEBEHDK_02587	1.78e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NIEBEHDK_02588	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_02589	4.89e-172	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_02590	1.75e-66	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_02591	7.49e-26	agaV	2.7.1.191	-	G	ko:K02745,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NIEBEHDK_02592	7.11e-257	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NIEBEHDK_02593	1.31e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_02594	5.57e-141	-	-	-	K	-	-	-	Bacterial transcriptional regulator
NIEBEHDK_02595	1.8e-181	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NIEBEHDK_02596	2.15e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIEBEHDK_02597	6.85e-114	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NIEBEHDK_02598	2.79e-192	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NIEBEHDK_02599	2.58e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIEBEHDK_02600	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
NIEBEHDK_02601	1.76e-246	-	-	-	G	-	-	-	Melibiase
NIEBEHDK_02602	9.75e-54	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_02603	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_02604	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_02605	9.21e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIEBEHDK_02606	8.53e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NIEBEHDK_02607	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
NIEBEHDK_02608	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NIEBEHDK_02609	4.66e-259	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NIEBEHDK_02610	6.58e-136	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
NIEBEHDK_02611	3.33e-161	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NIEBEHDK_02612	2.22e-78	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIEBEHDK_02613	9.61e-15	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIEBEHDK_02615	1.96e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
NIEBEHDK_02616	3.41e-257	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
NIEBEHDK_02617	3.01e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
NIEBEHDK_02618	1.94e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
NIEBEHDK_02619	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
NIEBEHDK_02620	6.76e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
NIEBEHDK_02621	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
NIEBEHDK_02622	1.33e-70	-	-	-	S	-	-	-	PRD domain
NIEBEHDK_02623	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02624	2.41e-158	-	-	-	H	-	-	-	Pfam:Transaldolase
NIEBEHDK_02625	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NIEBEHDK_02626	1.88e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
NIEBEHDK_02627	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NIEBEHDK_02628	2.53e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NIEBEHDK_02629	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NIEBEHDK_02630	4.82e-184	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NIEBEHDK_02631	5.59e-33	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NIEBEHDK_02632	6.82e-40	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
NIEBEHDK_02633	1.83e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NIEBEHDK_02634	3.56e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIEBEHDK_02635	2.13e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
NIEBEHDK_02636	4.27e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NIEBEHDK_02637	1.51e-147	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
NIEBEHDK_02638	3.93e-60	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02639	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIEBEHDK_02640	1.64e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEBEHDK_02641	2.97e-271	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
NIEBEHDK_02642	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NIEBEHDK_02643	5.44e-56	-	-	-	-	-	-	-	-
NIEBEHDK_02644	2.79e-199	-	-	-	GK	-	-	-	ROK family
NIEBEHDK_02645	1.23e-229	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NIEBEHDK_02646	1.68e-310	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
NIEBEHDK_02647	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NIEBEHDK_02648	2.05e-16	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NIEBEHDK_02649	3.89e-226	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NIEBEHDK_02650	5.24e-259	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NIEBEHDK_02651	6.25e-117	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NIEBEHDK_02652	7.2e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NIEBEHDK_02654	1.53e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
NIEBEHDK_02655	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NIEBEHDK_02656	2.06e-170	-	-	-	F	-	-	-	NUDIX domain
NIEBEHDK_02657	7.69e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
NIEBEHDK_02658	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIEBEHDK_02659	6.15e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NIEBEHDK_02660	2.81e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIEBEHDK_02661	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIEBEHDK_02662	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIEBEHDK_02663	2.51e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
NIEBEHDK_02664	9.24e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
NIEBEHDK_02665	7.56e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NIEBEHDK_02666	1.69e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NIEBEHDK_02667	2.54e-244	-	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_02668	1.47e-185	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIEBEHDK_02669	5.24e-208	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NIEBEHDK_02670	5.58e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NIEBEHDK_02671	5.03e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NIEBEHDK_02672	3.98e-172	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NIEBEHDK_02674	1.76e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
NIEBEHDK_02675	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NIEBEHDK_02676	3.72e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NIEBEHDK_02677	1.23e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NIEBEHDK_02678	3.29e-182	-	-	-	Q	-	-	-	Methyltransferase
NIEBEHDK_02679	2.34e-65	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
NIEBEHDK_02680	8.78e-08	-	-	-	S	-	-	-	SpoVT / AbrB like domain
NIEBEHDK_02681	1.17e-178	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_02682	1.5e-74	-	-	-	-	-	-	-	-
NIEBEHDK_02683	2.09e-48	-	-	-	-	-	-	-	-
NIEBEHDK_02684	5.69e-140	-	-	-	S	-	-	-	alpha beta
NIEBEHDK_02685	8.86e-103	yfbM	-	-	K	-	-	-	FR47-like protein
NIEBEHDK_02686	6.78e-100	-	-	-	E	-	-	-	HAD-hyrolase-like
NIEBEHDK_02687	2.78e-170	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NIEBEHDK_02688	9.36e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_02689	1.69e-158	-	-	-	-	-	-	-	-
NIEBEHDK_02690	1.33e-86	-	-	-	S	-	-	-	ASCH
NIEBEHDK_02691	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIEBEHDK_02692	7.69e-254	ysdE	-	-	P	-	-	-	Citrate transporter
NIEBEHDK_02693	6.3e-134	-	-	-	-	-	-	-	-
NIEBEHDK_02694	5.64e-315	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NIEBEHDK_02695	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NIEBEHDK_02696	9.87e-200	-	-	-	-	-	-	-	-
NIEBEHDK_02697	0.0	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NIEBEHDK_02698	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
NIEBEHDK_02699	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
NIEBEHDK_02700	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NIEBEHDK_02701	4.09e-99	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
NIEBEHDK_02702	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NIEBEHDK_02703	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NIEBEHDK_02704	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NIEBEHDK_02705	3.66e-183	yycI	-	-	S	-	-	-	YycH protein
NIEBEHDK_02706	0.0	yycH	-	-	S	-	-	-	YycH protein
NIEBEHDK_02707	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIEBEHDK_02708	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NIEBEHDK_02709	1.1e-159	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
NIEBEHDK_02710	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NIEBEHDK_02711	3.99e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIEBEHDK_02712	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NIEBEHDK_02713	4.59e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NIEBEHDK_02714	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NIEBEHDK_02715	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEBEHDK_02716	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NIEBEHDK_02717	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIEBEHDK_02718	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
NIEBEHDK_02719	5.23e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_02720	1.14e-105	-	-	-	F	-	-	-	NUDIX domain
NIEBEHDK_02721	5.71e-116	-	-	-	S	-	-	-	AAA domain
NIEBEHDK_02722	2.16e-148	-	-	-	S	-	-	-	Phage terminase large subunit
NIEBEHDK_02723	0.0	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02724	2.27e-89	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NIEBEHDK_02725	0.0	-	-	-	L	-	-	-	Transposase DDE domain
NIEBEHDK_02726	8.37e-161	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
NIEBEHDK_02727	3.21e-112	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEBEHDK_02728	1.14e-104	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NIEBEHDK_02729	1.01e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NIEBEHDK_02730	3.48e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NIEBEHDK_02731	2.2e-28	-	-	-	S	-	-	-	AAA domain
NIEBEHDK_02735	4.31e-115	-	-	-	-	-	-	-	-
NIEBEHDK_02736	5.11e-149	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NIEBEHDK_02737	3.1e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIEBEHDK_02738	5.18e-75	-	-	-	-	-	-	-	-
NIEBEHDK_02739	3.7e-60	-	-	-	-	-	-	-	-
NIEBEHDK_02740	4.76e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
NIEBEHDK_02741	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
NIEBEHDK_02742	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEBEHDK_02743	4.01e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NIEBEHDK_02744	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
NIEBEHDK_02745	2.65e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NIEBEHDK_02746	1.71e-17	-	-	-	-	-	-	-	-
NIEBEHDK_02747	3.33e-78	-	-	-	-	-	-	-	-
NIEBEHDK_02748	5.39e-183	-	-	-	S	-	-	-	hydrolase
NIEBEHDK_02749	9.22e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
NIEBEHDK_02750	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
NIEBEHDK_02751	4.69e-94	-	-	-	K	-	-	-	MarR family
NIEBEHDK_02752	1.13e-138	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEBEHDK_02753	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NIEBEHDK_02755	6.32e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIEBEHDK_02756	9.8e-167	ydfF	-	-	K	-	-	-	Transcriptional
NIEBEHDK_02757	1.22e-170	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIEBEHDK_02758	5.4e-175	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NIEBEHDK_02759	2.03e-225	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
NIEBEHDK_02760	4.46e-189	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
NIEBEHDK_02761	0.0	-	-	-	L	-	-	-	DNA helicase
NIEBEHDK_02762	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIEBEHDK_02763	2.58e-226	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02764	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NIEBEHDK_02765	9.24e-91	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIEBEHDK_02766	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIEBEHDK_02767	4.87e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NIEBEHDK_02768	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
NIEBEHDK_02769	1.3e-302	dinF	-	-	V	-	-	-	MatE
NIEBEHDK_02770	2.02e-75	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NIEBEHDK_02771	2.25e-28	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NIEBEHDK_02772	2.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NIEBEHDK_02773	7.95e-221	ydhF	-	-	S	-	-	-	Aldo keto reductase
NIEBEHDK_02774	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NIEBEHDK_02775	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIEBEHDK_02776	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NIEBEHDK_02777	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NIEBEHDK_02778	3.78e-51	-	-	-	-	-	-	-	-
NIEBEHDK_02779	1.12e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NIEBEHDK_02780	6.25e-217	-	-	-	-	-	-	-	-
NIEBEHDK_02782	3.42e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NIEBEHDK_02783	2.35e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NIEBEHDK_02784	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NIEBEHDK_02785	4.46e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NIEBEHDK_02786	1.35e-193	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NIEBEHDK_02787	8.68e-220	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NIEBEHDK_02788	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIEBEHDK_02789	3.43e-85	-	-	-	-	-	-	-	-
NIEBEHDK_02790	3.93e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NIEBEHDK_02791	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIEBEHDK_02792	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIEBEHDK_02793	3.2e-212	-	-	-	T	-	-	-	GHKL domain
NIEBEHDK_02794	1.23e-161	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NIEBEHDK_02795	3e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
NIEBEHDK_02796	4.53e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
NIEBEHDK_02797	7.89e-105	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIEBEHDK_02798	7.18e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NIEBEHDK_02799	5.35e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIEBEHDK_02800	1.61e-196	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIEBEHDK_02801	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NIEBEHDK_02802	8.83e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIEBEHDK_02803	6.67e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NIEBEHDK_02804	1.38e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NIEBEHDK_02805	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02806	1.37e-160	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NIEBEHDK_02807	1.84e-281	ysaA	-	-	V	-	-	-	RDD family
NIEBEHDK_02808	3.01e-295	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIEBEHDK_02809	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEBEHDK_02810	6.37e-67	nudA	-	-	S	-	-	-	ASCH
NIEBEHDK_02811	1.16e-95	-	-	-	-	-	-	-	-
NIEBEHDK_02812	2.82e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIEBEHDK_02813	3.18e-239	-	-	-	S	-	-	-	DUF218 domain
NIEBEHDK_02814	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NIEBEHDK_02815	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NIEBEHDK_02816	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NIEBEHDK_02817	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NIEBEHDK_02818	3.09e-103	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIEBEHDK_02819	4.99e-194	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NIEBEHDK_02822	2.23e-279	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NIEBEHDK_02823	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIEBEHDK_02825	3.31e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIEBEHDK_02826	1.09e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NIEBEHDK_02827	8.42e-299	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIEBEHDK_02829	2.02e-83	-	-	-	-	-	-	-	-
NIEBEHDK_02830	1.7e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF1492)
NIEBEHDK_02831	2.18e-169	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NIEBEHDK_02832	5.32e-78	-	-	-	S	-	-	-	Phage Mu protein F like protein
NIEBEHDK_02833	3.21e-72	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
NIEBEHDK_02834	1.6e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIEBEHDK_02835	9.51e-160	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
NIEBEHDK_02837	3.11e-54	-	-	-	-	-	-	-	-
NIEBEHDK_02838	1.75e-149	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIEBEHDK_02839	9.06e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NIEBEHDK_02840	1.03e-263	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
NIEBEHDK_02841	1.09e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIEBEHDK_02842	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_02843	1.17e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NIEBEHDK_02844	1.59e-286	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NIEBEHDK_02845	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NIEBEHDK_02846	9.63e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIEBEHDK_02847	6.18e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NIEBEHDK_02848	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIEBEHDK_02849	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIEBEHDK_02850	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIEBEHDK_02851	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIEBEHDK_02852	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NIEBEHDK_02853	5.81e-272	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIEBEHDK_02854	6.02e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIEBEHDK_02855	2.72e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NIEBEHDK_02857	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIEBEHDK_02858	2.98e-18	-	-	-	-	-	-	-	-
NIEBEHDK_02859	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIEBEHDK_02860	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NIEBEHDK_02861	6.69e-39	-	-	-	-	-	-	-	-
NIEBEHDK_02862	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NIEBEHDK_02863	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NIEBEHDK_02864	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIEBEHDK_02865	1.88e-307	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NIEBEHDK_02866	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
NIEBEHDK_02867	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NIEBEHDK_02868	1.16e-124	-	-	-	-	-	-	-	-
NIEBEHDK_02869	1.73e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NIEBEHDK_02870	7.6e-176	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NIEBEHDK_02871	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02872	2.24e-84	-	-	-	-	-	-	-	-
NIEBEHDK_02873	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEBEHDK_02874	2.78e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NIEBEHDK_02875	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NIEBEHDK_02877	8.72e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NIEBEHDK_02878	4.29e-265	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NIEBEHDK_02879	7.3e-268	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NIEBEHDK_02880	6.7e-62	-	-	-	-	-	-	-	-
NIEBEHDK_02881	5.52e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NIEBEHDK_02882	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
NIEBEHDK_02883	2.96e-204	-	-	-	G	-	-	-	Aldose 1-epimerase
NIEBEHDK_02884	4.58e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NIEBEHDK_02885	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NIEBEHDK_02887	1.4e-105	-	-	-	K	-	-	-	FR47-like protein
NIEBEHDK_02888	8.49e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NIEBEHDK_02889	1.59e-165	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02890	1.25e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIEBEHDK_02891	1.54e-224	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NIEBEHDK_02892	2.37e-95	-	-	-	-	-	-	-	-
NIEBEHDK_02893	3.02e-82	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_02894	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NIEBEHDK_02895	1.01e-275	-	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_02896	4.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIEBEHDK_02897	1.3e-284	-	-	-	V	-	-	-	Beta-lactamase
NIEBEHDK_02898	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIEBEHDK_02899	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NIEBEHDK_02900	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIEBEHDK_02901	7.93e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIEBEHDK_02902	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
NIEBEHDK_02903	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NIEBEHDK_02904	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NIEBEHDK_02906	1.92e-200	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIEBEHDK_02907	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NIEBEHDK_02908	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIEBEHDK_02909	2.43e-87	-	-	-	-	-	-	-	-
NIEBEHDK_02910	1.39e-96	-	-	-	S	-	-	-	function, without similarity to other proteins
NIEBEHDK_02911	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
NIEBEHDK_02912	1.17e-295	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NIEBEHDK_02913	3.89e-75	-	-	-	-	-	-	-	-
NIEBEHDK_02914	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
NIEBEHDK_02915	4.52e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
NIEBEHDK_02916	8.39e-314	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NIEBEHDK_02917	9.93e-175	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NIEBEHDK_02918	3.58e-128	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
NIEBEHDK_02919	1.42e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NIEBEHDK_02920	8.63e-31	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NIEBEHDK_02922	4.55e-71	-	-	-	S	-	-	-	CpXC protein
NIEBEHDK_02924	0.000514	-	-	-	S	-	-	-	Protein of unknown function (DUF1659)
NIEBEHDK_02927	1.69e-73	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NIEBEHDK_02930	1.5e-178	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
NIEBEHDK_02931	1.62e-131	-	-	-	S	-	-	-	ABC transporter
NIEBEHDK_02932	8.01e-209	-	-	-	S	-	-	-	ABC transporter
NIEBEHDK_02933	7.94e-220	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
NIEBEHDK_02934	8.37e-136	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NIEBEHDK_02935	4.9e-69	-	-	-	-	-	-	-	-
NIEBEHDK_02936	6.35e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NIEBEHDK_02937	5.69e-189	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIEBEHDK_02938	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_02939	4.98e-98	-	-	-	T	-	-	-	Sh3 type 3 domain protein
NIEBEHDK_02940	2.15e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NIEBEHDK_02941	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NIEBEHDK_02942	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NIEBEHDK_02943	3.89e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NIEBEHDK_02944	6.52e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NIEBEHDK_02945	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NIEBEHDK_02946	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIEBEHDK_02947	3.08e-74	-	-	-	-	-	-	-	-
NIEBEHDK_02948	4.61e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NIEBEHDK_02949	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NIEBEHDK_02950	2.94e-54	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NIEBEHDK_02951	5.44e-150	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NIEBEHDK_02952	5.62e-190	gntR	-	-	K	-	-	-	rpiR family
NIEBEHDK_02953	2.1e-215	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
NIEBEHDK_02954	1.2e-203	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
NIEBEHDK_02955	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
NIEBEHDK_02956	5.48e-202	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIEBEHDK_02957	2.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NIEBEHDK_02958	2.96e-165	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NIEBEHDK_02959	1.67e-60	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NIEBEHDK_02960	1.12e-245	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NIEBEHDK_02961	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NIEBEHDK_02962	6.58e-227	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NIEBEHDK_02963	1.64e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NIEBEHDK_02964	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NIEBEHDK_02965	1.09e-286	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIEBEHDK_02967	1.13e-181	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
NIEBEHDK_02968	1.93e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
NIEBEHDK_02969	1.83e-180	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NIEBEHDK_02970	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIEBEHDK_02971	2.55e-111	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEBEHDK_02972	5.54e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NIEBEHDK_02973	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
NIEBEHDK_02974	1.68e-156	vanR	-	-	K	-	-	-	response regulator
NIEBEHDK_02975	1.67e-152	-	-	-	-	-	-	-	-
NIEBEHDK_02976	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEBEHDK_02977	2.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NIEBEHDK_02978	4.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIEBEHDK_02979	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NIEBEHDK_02980	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NIEBEHDK_02981	3.67e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NIEBEHDK_02982	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NIEBEHDK_02983	9.03e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NIEBEHDK_02984	2.32e-86	-	-	-	-	-	-	-	-
NIEBEHDK_02985	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NIEBEHDK_02987	1.89e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NIEBEHDK_02988	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIEBEHDK_02989	5.63e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
NIEBEHDK_02990	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
NIEBEHDK_02991	2.73e-166	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NIEBEHDK_02992	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NIEBEHDK_02993	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NIEBEHDK_02994	1.32e-39	-	-	-	-	-	-	-	-
NIEBEHDK_02995	1.68e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
NIEBEHDK_02996	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
NIEBEHDK_02997	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NIEBEHDK_02998	5.78e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEBEHDK_02999	4.87e-37	-	-	-	-	-	-	-	-
NIEBEHDK_03000	4.57e-49	-	-	-	-	-	-	-	-
NIEBEHDK_03001	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
NIEBEHDK_03002	7.43e-69	-	-	-	-	-	-	-	-
NIEBEHDK_03003	5.12e-84	-	-	-	-	-	-	-	-
NIEBEHDK_03004	1.47e-07	-	-	-	-	-	-	-	-
NIEBEHDK_03005	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
NIEBEHDK_03006	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NIEBEHDK_03007	8.84e-274	-	-	-	S	ko:K06872	-	ko00000	TPM domain
NIEBEHDK_03008	6.18e-150	-	-	-	-	-	-	-	-
NIEBEHDK_03009	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NIEBEHDK_03010	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
NIEBEHDK_03011	2.66e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
NIEBEHDK_03012	5.25e-106	-	-	-	S	-	-	-	NUDIX domain
NIEBEHDK_03013	2.2e-97	-	-	-	-	-	-	-	-
NIEBEHDK_03014	2.8e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIEBEHDK_03015	6.5e-162	-	-	-	-	-	-	-	-
NIEBEHDK_03016	6.05e-118	-	-	-	-	-	-	-	-