ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HIEBNEHA_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIEBNEHA_00002 3.86e-261 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIEBNEHA_00003 1.09e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HIEBNEHA_00004 2.7e-258 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIEBNEHA_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIEBNEHA_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIEBNEHA_00007 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HIEBNEHA_00008 1.34e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIEBNEHA_00009 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIEBNEHA_00010 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_00011 6.17e-41 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIEBNEHA_00012 2.33e-60 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIEBNEHA_00013 1.73e-128 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HIEBNEHA_00014 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HIEBNEHA_00015 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HIEBNEHA_00016 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HIEBNEHA_00017 9.25e-270 yttB - - EGP - - - Major Facilitator
HIEBNEHA_00018 7.71e-81 - - - - - - - -
HIEBNEHA_00019 2.53e-208 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HIEBNEHA_00020 1.58e-157 - - - S - - - Fic/DOC family
HIEBNEHA_00022 6.3e-95 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HIEBNEHA_00023 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HIEBNEHA_00025 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HIEBNEHA_00026 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIEBNEHA_00027 1.09e-311 yycH - - S - - - YycH protein
HIEBNEHA_00028 1.18e-191 yycI - - S - - - YycH protein
HIEBNEHA_00029 1.46e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HIEBNEHA_00030 7.56e-286 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HIEBNEHA_00032 1.47e-110 pgpA - - I - - - Phosphatidylglycerophosphatase A
HIEBNEHA_00033 1e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_00034 4.36e-114 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIEBNEHA_00036 6.12e-123 - - - S - - - reductase
HIEBNEHA_00037 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HIEBNEHA_00038 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HIEBNEHA_00039 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_00040 1.52e-192 - - - E - - - Glyoxalase-like domain
HIEBNEHA_00041 2.13e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIEBNEHA_00042 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HIEBNEHA_00043 1.36e-198 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIEBNEHA_00044 3.99e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_00045 1.31e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HIEBNEHA_00046 5.89e-115 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_00047 3.12e-67 - - - - - - - -
HIEBNEHA_00048 0.0 - - - S - - - Putative peptidoglycan binding domain
HIEBNEHA_00052 3.99e-68 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_00053 1.79e-111 - - - K - - - FR47-like protein
HIEBNEHA_00054 6.86e-98 - - - O - - - OsmC-like protein
HIEBNEHA_00055 3.47e-221 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIEBNEHA_00056 1.13e-272 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_00057 2.49e-43 - - - - - - - -
HIEBNEHA_00058 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HIEBNEHA_00060 9.22e-135 - - - K - - - PFAM GCN5-related N-acetyltransferase
HIEBNEHA_00061 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIEBNEHA_00062 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIEBNEHA_00063 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HIEBNEHA_00064 4.97e-220 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HIEBNEHA_00065 2.57e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HIEBNEHA_00066 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HIEBNEHA_00067 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HIEBNEHA_00068 1.02e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HIEBNEHA_00069 2.83e-90 - - - - - - - -
HIEBNEHA_00070 1.02e-111 - - - T - - - Region found in RelA / SpoT proteins
HIEBNEHA_00071 9.03e-153 dltr - - K - - - response regulator
HIEBNEHA_00072 1.32e-288 sptS - - T - - - Histidine kinase
HIEBNEHA_00073 7.12e-275 - - - P - - - Voltage gated chloride channel
HIEBNEHA_00074 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HIEBNEHA_00075 1.45e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HIEBNEHA_00076 1.48e-214 - - - C - - - Aldo keto reductase
HIEBNEHA_00077 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HIEBNEHA_00078 3.77e-113 - - - S - - - ECF-type riboflavin transporter, S component
HIEBNEHA_00079 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HIEBNEHA_00080 2.42e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIEBNEHA_00081 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIEBNEHA_00082 1.56e-117 - - - - - - - -
HIEBNEHA_00083 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIEBNEHA_00085 1.11e-16 - - - E - - - amino acid
HIEBNEHA_00086 2.53e-17 - - - K - - - Transcriptional regulator, TetR family
HIEBNEHA_00087 4.05e-39 - - - K - - - Transcriptional regulator, TetR family
HIEBNEHA_00088 8.53e-95 - - - - - - - -
HIEBNEHA_00089 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HIEBNEHA_00090 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HIEBNEHA_00091 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HIEBNEHA_00092 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HIEBNEHA_00093 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HIEBNEHA_00094 6.68e-241 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_00095 6.49e-74 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_00096 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HIEBNEHA_00097 9.89e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HIEBNEHA_00098 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HIEBNEHA_00099 1.16e-223 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HIEBNEHA_00100 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIEBNEHA_00101 2.01e-130 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HIEBNEHA_00102 1.27e-259 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HIEBNEHA_00103 1.39e-225 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIEBNEHA_00104 1.28e-35 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_00105 1.67e-45 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_00106 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIEBNEHA_00107 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIEBNEHA_00108 3.28e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00109 2.51e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HIEBNEHA_00110 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_00111 2.4e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HIEBNEHA_00112 8.26e-219 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HIEBNEHA_00113 1.47e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HIEBNEHA_00114 1.36e-157 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HIEBNEHA_00115 3.79e-193 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HIEBNEHA_00116 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HIEBNEHA_00117 1.38e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HIEBNEHA_00118 2.37e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HIEBNEHA_00119 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIEBNEHA_00120 4.25e-173 - - - S - - - Protein of unknown function (DUF1129)
HIEBNEHA_00121 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIEBNEHA_00122 4.64e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HIEBNEHA_00123 6.43e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HIEBNEHA_00124 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HIEBNEHA_00125 6.79e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HIEBNEHA_00126 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIEBNEHA_00127 9.76e-161 vanR - - K - - - response regulator
HIEBNEHA_00128 3.73e-264 hpk31 - - T - - - Histidine kinase
HIEBNEHA_00129 9.75e-186 - - - E - - - AzlC protein
HIEBNEHA_00130 4.05e-70 - - - S - - - branched-chain amino acid
HIEBNEHA_00131 2.75e-166 - - - K - - - LysR substrate binding domain
HIEBNEHA_00132 2.57e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HIEBNEHA_00133 7.12e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIEBNEHA_00134 5.36e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIEBNEHA_00135 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIEBNEHA_00136 1.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIEBNEHA_00137 1.51e-147 - - - S - - - Haloacid dehalogenase-like hydrolase
HIEBNEHA_00138 2.62e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIEBNEHA_00139 1.64e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HIEBNEHA_00140 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_00141 3.86e-223 ydbI - - K - - - AI-2E family transporter
HIEBNEHA_00142 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HIEBNEHA_00143 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIEBNEHA_00144 6.34e-166 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HIEBNEHA_00145 7.63e-27 rhaS4 - - K - - - helix_turn_helix, arabinose operon control protein
HIEBNEHA_00146 6.23e-233 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HIEBNEHA_00147 2.08e-218 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HIEBNEHA_00148 1e-126 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIEBNEHA_00149 5.18e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIEBNEHA_00150 5.01e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIEBNEHA_00151 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIEBNEHA_00152 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HIEBNEHA_00153 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIEBNEHA_00154 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIEBNEHA_00155 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIEBNEHA_00156 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIEBNEHA_00157 1.95e-250 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HIEBNEHA_00158 2.37e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIEBNEHA_00159 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HIEBNEHA_00160 1.17e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HIEBNEHA_00161 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIEBNEHA_00162 1.59e-226 - - - - - - - -
HIEBNEHA_00163 6.7e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIEBNEHA_00164 6.36e-75 - - - - - - - -
HIEBNEHA_00170 8.49e-08 - - - K - - - peptidyl-tyrosine sulfation
HIEBNEHA_00172 3.84e-61 - - - D - - - nuclear chromosome segregation
HIEBNEHA_00173 0.000462 - - - D - - - nuclear chromosome segregation
HIEBNEHA_00180 1.17e-149 - - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_00181 1.83e-06 - - - - - - - -
HIEBNEHA_00182 1.5e-213 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HIEBNEHA_00183 6.42e-45 - - - K - - - transcriptional regulator, MerR family
HIEBNEHA_00184 1.67e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
HIEBNEHA_00185 1.05e-134 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_00186 4.01e-216 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIEBNEHA_00187 3.35e-59 - - - S - - - Pfam:DUF59
HIEBNEHA_00188 4.48e-90 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HIEBNEHA_00189 3.23e-249 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HIEBNEHA_00192 1.27e-48 - - - M - - - Rib/alpha-like repeat
HIEBNEHA_00193 1.68e-197 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_00194 4e-264 - - - M - - - Rib/alpha-like repeat
HIEBNEHA_00195 2.76e-305 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HIEBNEHA_00196 6.78e-165 - - - IQ - - - dehydrogenase reductase
HIEBNEHA_00197 4.54e-49 - - - - - - - -
HIEBNEHA_00198 9.4e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HIEBNEHA_00199 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
HIEBNEHA_00200 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HIEBNEHA_00201 1.39e-232 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIEBNEHA_00203 7.73e-127 - - - S ko:K07002 - ko00000 Serine hydrolase
HIEBNEHA_00204 1.01e-35 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HIEBNEHA_00205 8.54e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIEBNEHA_00207 9.37e-228 ydhF - - S - - - Aldo keto reductase
HIEBNEHA_00208 1.2e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
HIEBNEHA_00209 0.0 - - - L - - - Helicase C-terminal domain protein
HIEBNEHA_00211 4.48e-312 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HIEBNEHA_00212 6.21e-68 - - - S - - - Sugar efflux transporter for intercellular exchange
HIEBNEHA_00213 2.12e-162 - - - - - - - -
HIEBNEHA_00214 1.12e-162 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HIEBNEHA_00215 0.0 cadA - - P - - - P-type ATPase
HIEBNEHA_00216 1.63e-279 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HIEBNEHA_00217 4.44e-11 - - - - - - - -
HIEBNEHA_00218 2.68e-45 - - - GM - - - NAD(P)H-binding
HIEBNEHA_00219 1.08e-65 - - - GM - - - NAD(P)H-binding
HIEBNEHA_00220 3.71e-95 ywnA - - K - - - Transcriptional regulator
HIEBNEHA_00221 2.16e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HIEBNEHA_00222 7.85e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_00223 3.69e-183 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00224 1.32e-136 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HIEBNEHA_00225 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HIEBNEHA_00226 2.16e-75 eriC - - P ko:K03281 - ko00000 chloride
HIEBNEHA_00227 1.3e-34 eriC - - P ko:K03281 - ko00000 chloride
HIEBNEHA_00228 2.1e-270 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HIEBNEHA_00229 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_00230 2e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIEBNEHA_00231 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HIEBNEHA_00232 4.93e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HIEBNEHA_00233 9.83e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HIEBNEHA_00234 4.73e-53 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HIEBNEHA_00235 1.64e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIEBNEHA_00236 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HIEBNEHA_00237 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIEBNEHA_00239 7.77e-261 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIEBNEHA_00240 0.0 - - - L - - - DNA helicase
HIEBNEHA_00241 4.08e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HIEBNEHA_00242 8.74e-234 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HIEBNEHA_00243 2.26e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HIEBNEHA_00244 3.08e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HIEBNEHA_00245 6.78e-289 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HIEBNEHA_00246 3.01e-225 - - - - - - - -
HIEBNEHA_00247 4.85e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HIEBNEHA_00249 2.25e-206 yunF - - F - - - Protein of unknown function DUF72
HIEBNEHA_00250 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIEBNEHA_00251 3.58e-198 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HIEBNEHA_00252 1.22e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIEBNEHA_00253 1.2e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIEBNEHA_00254 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
HIEBNEHA_00255 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIEBNEHA_00256 3.34e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HIEBNEHA_00257 1.98e-157 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HIEBNEHA_00258 6.12e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HIEBNEHA_00259 6e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HIEBNEHA_00260 1.24e-311 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIEBNEHA_00261 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIEBNEHA_00262 1.19e-98 - - - - - - - -
HIEBNEHA_00263 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_00264 1.28e-187 yidA - - S - - - hydrolase
HIEBNEHA_00265 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HIEBNEHA_00266 3.54e-190 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HIEBNEHA_00267 2.84e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_00268 2.56e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_00269 3.15e-71 ywiB - - S - - - Domain of unknown function (DUF1934)
HIEBNEHA_00270 2.44e-84 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIEBNEHA_00271 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIEBNEHA_00272 1.11e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIEBNEHA_00273 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HIEBNEHA_00274 7.23e-300 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIEBNEHA_00275 1.78e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HIEBNEHA_00276 1.18e-159 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HIEBNEHA_00277 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HIEBNEHA_00278 8.03e-194 - - - G - - - Right handed beta helix region
HIEBNEHA_00279 8.28e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIEBNEHA_00280 5.32e-208 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HIEBNEHA_00281 1.84e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
HIEBNEHA_00282 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIEBNEHA_00283 9.94e-123 lemA - - S ko:K03744 - ko00000 LemA family
HIEBNEHA_00284 3.7e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HIEBNEHA_00285 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIEBNEHA_00286 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIEBNEHA_00287 4.68e-197 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIEBNEHA_00288 3.55e-214 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HIEBNEHA_00289 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIEBNEHA_00290 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIEBNEHA_00291 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HIEBNEHA_00292 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIEBNEHA_00293 4.54e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HIEBNEHA_00294 5.89e-115 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_00295 8.96e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIEBNEHA_00296 9.94e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIEBNEHA_00297 5.31e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HIEBNEHA_00298 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HIEBNEHA_00299 1.59e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HIEBNEHA_00300 2.69e-184 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HIEBNEHA_00301 3.29e-146 - - - S - - - (CBS) domain
HIEBNEHA_00302 1.13e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIEBNEHA_00303 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIEBNEHA_00304 1.01e-52 yabO - - J - - - S4 domain protein
HIEBNEHA_00305 4.14e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HIEBNEHA_00306 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HIEBNEHA_00307 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIEBNEHA_00308 8.67e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HIEBNEHA_00309 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIEBNEHA_00310 9.26e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIEBNEHA_00311 6.21e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIEBNEHA_00312 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HIEBNEHA_00313 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_00314 4.14e-23 - - - K - - - Cro/C1-type HTH DNA-binding domain
HIEBNEHA_00315 1.61e-67 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIEBNEHA_00316 1.96e-184 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HIEBNEHA_00317 1.51e-126 - - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HIEBNEHA_00318 1.33e-170 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00319 8.56e-162 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HIEBNEHA_00320 2.79e-193 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HIEBNEHA_00321 1.29e-231 - - - G - - - Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HIEBNEHA_00322 8.9e-65 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIEBNEHA_00323 6.03e-221 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIEBNEHA_00324 8.15e-136 - - - L - - - Helix-turn-helix domain
HIEBNEHA_00325 4.25e-153 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_00331 1.23e-99 tnpR1 - - L - - - Resolvase, N terminal domain
HIEBNEHA_00333 3.28e-15 - - - S - - - Helix-turn-helix domain
HIEBNEHA_00334 3.18e-160 - - - - - - - -
HIEBNEHA_00337 2.31e-27 - - - S - - - DNA binding domain, excisionase family
HIEBNEHA_00338 4.39e-213 int7 - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_00339 4.08e-107 - - - - - - - -
HIEBNEHA_00340 6.36e-75 - - - - - - - -
HIEBNEHA_00344 2.03e-141 - - - L - - - Bacterial dnaA protein
HIEBNEHA_00345 5.69e-152 - - - L - - - Integrase core domain
HIEBNEHA_00347 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_00348 5.7e-293 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00349 5.51e-49 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00353 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HIEBNEHA_00354 3.03e-192 - - - S - - - Calcineurin-like phosphoesterase
HIEBNEHA_00357 2.68e-144 - - - - - - - -
HIEBNEHA_00358 3.57e-316 - - - EGP - - - Major Facilitator
HIEBNEHA_00359 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HIEBNEHA_00360 3.53e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HIEBNEHA_00361 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HIEBNEHA_00362 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIEBNEHA_00363 1.02e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIEBNEHA_00364 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HIEBNEHA_00365 6.46e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HIEBNEHA_00367 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HIEBNEHA_00368 1.57e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HIEBNEHA_00369 0.0 - - - S - - - Bacterial membrane protein, YfhO
HIEBNEHA_00370 2.92e-170 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIEBNEHA_00371 8.91e-216 - - - I - - - alpha/beta hydrolase fold
HIEBNEHA_00372 1.74e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HIEBNEHA_00373 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIEBNEHA_00374 1.01e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00375 1.95e-177 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HIEBNEHA_00376 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HIEBNEHA_00377 5.89e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIEBNEHA_00378 4.73e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HIEBNEHA_00379 4.86e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HIEBNEHA_00380 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIEBNEHA_00381 5.49e-262 yacL - - S - - - domain protein
HIEBNEHA_00382 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HIEBNEHA_00383 2.95e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIEBNEHA_00384 7.41e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIEBNEHA_00385 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HIEBNEHA_00386 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIEBNEHA_00387 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HIEBNEHA_00388 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIEBNEHA_00389 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIEBNEHA_00390 2.96e-285 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HIEBNEHA_00392 1.15e-40 - - - M - - - Glycosyl transferase family group 2
HIEBNEHA_00393 3.96e-194 - - - M - - - Glycosyl transferase family group 2
HIEBNEHA_00394 7.6e-269 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIEBNEHA_00395 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIEBNEHA_00396 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIEBNEHA_00397 1.32e-64 - - - - - - - -
HIEBNEHA_00398 1.75e-179 - - - L - - - Bacterial dnaA protein
HIEBNEHA_00399 3.38e-294 - - - L - - - Integrase core domain
HIEBNEHA_00400 3.29e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIEBNEHA_00401 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HIEBNEHA_00402 6.31e-126 - - - S - - - Protein of unknown function (DUF1700)
HIEBNEHA_00403 7.95e-171 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HIEBNEHA_00404 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HIEBNEHA_00405 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIEBNEHA_00406 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIEBNEHA_00407 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HIEBNEHA_00408 1.16e-114 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIEBNEHA_00409 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIEBNEHA_00410 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIEBNEHA_00411 1.65e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIEBNEHA_00412 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
HIEBNEHA_00413 3.41e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIEBNEHA_00414 1.64e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
HIEBNEHA_00415 7.16e-233 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HIEBNEHA_00416 1.77e-74 yabA - - L - - - Involved in initiation control of chromosome replication
HIEBNEHA_00417 4.31e-198 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIEBNEHA_00418 1.18e-173 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HIEBNEHA_00419 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_00420 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HIEBNEHA_00421 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HIEBNEHA_00422 2.44e-217 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HIEBNEHA_00423 5.54e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HIEBNEHA_00424 7.34e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HIEBNEHA_00425 9.73e-132 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HIEBNEHA_00426 2.18e-246 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIEBNEHA_00427 4.92e-168 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIEBNEHA_00428 1.42e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIEBNEHA_00429 1.48e-176 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIEBNEHA_00430 2.47e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HIEBNEHA_00431 8.5e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_00432 8.39e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIEBNEHA_00433 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HIEBNEHA_00434 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIEBNEHA_00436 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIEBNEHA_00437 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIEBNEHA_00438 7.32e-105 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HIEBNEHA_00439 0.0 - - - E - - - amino acid
HIEBNEHA_00440 0.0 ydaO - - E - - - amino acid
HIEBNEHA_00441 1.53e-52 - - - - - - - -
HIEBNEHA_00442 1.21e-135 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_00443 1.44e-139 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HIEBNEHA_00444 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HIEBNEHA_00445 4.08e-147 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HIEBNEHA_00446 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIEBNEHA_00447 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIEBNEHA_00448 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIEBNEHA_00449 4.27e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HIEBNEHA_00450 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HIEBNEHA_00451 3.96e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIEBNEHA_00452 9.5e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIEBNEHA_00453 9.42e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HIEBNEHA_00454 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HIEBNEHA_00455 8.71e-176 lutC - - S ko:K00782 - ko00000 LUD domain
HIEBNEHA_00456 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HIEBNEHA_00457 3.22e-214 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HIEBNEHA_00458 1.37e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIEBNEHA_00459 1.75e-257 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HIEBNEHA_00460 4.9e-207 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
HIEBNEHA_00461 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HIEBNEHA_00462 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIEBNEHA_00463 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HIEBNEHA_00464 1.03e-19 - - - - - - - -
HIEBNEHA_00465 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIEBNEHA_00466 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIEBNEHA_00467 4.5e-315 steT - - E ko:K03294 - ko00000 amino acid
HIEBNEHA_00468 1.63e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HIEBNEHA_00469 9.5e-238 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HIEBNEHA_00470 1.59e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HIEBNEHA_00472 1.83e-21 - - - - - - - -
HIEBNEHA_00473 4.97e-131 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_00474 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIEBNEHA_00476 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIEBNEHA_00477 4.41e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HIEBNEHA_00478 1.45e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIEBNEHA_00479 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIEBNEHA_00480 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HIEBNEHA_00481 0.0 eriC - - P ko:K03281 - ko00000 chloride
HIEBNEHA_00482 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HIEBNEHA_00483 5.57e-167 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HIEBNEHA_00484 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIEBNEHA_00485 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIEBNEHA_00486 6.49e-135 - - - - - - - -
HIEBNEHA_00487 4.35e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIEBNEHA_00488 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HIEBNEHA_00489 3.44e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HIEBNEHA_00490 2.63e-115 - - - K - - - Acetyltransferase (GNAT) domain
HIEBNEHA_00491 1.19e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HIEBNEHA_00492 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HIEBNEHA_00493 2.76e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HIEBNEHA_00494 1.25e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIEBNEHA_00495 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIEBNEHA_00496 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HIEBNEHA_00497 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIEBNEHA_00498 5.7e-165 ybbR - - S - - - YbbR-like protein
HIEBNEHA_00499 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIEBNEHA_00500 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIEBNEHA_00501 3e-69 - - - - - - - -
HIEBNEHA_00502 0.0 oatA - - I - - - Acyltransferase
HIEBNEHA_00503 6.2e-103 - - - K - - - Transcriptional regulator
HIEBNEHA_00504 3.16e-190 - - - S - - - Cof-like hydrolase
HIEBNEHA_00505 5.34e-108 lytE - - M - - - Lysin motif
HIEBNEHA_00507 2.81e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HIEBNEHA_00508 0.0 yclK - - T - - - Histidine kinase
HIEBNEHA_00509 2.14e-197 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HIEBNEHA_00510 1.07e-138 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HIEBNEHA_00511 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HIEBNEHA_00512 1.1e-35 - - - - - - - -
HIEBNEHA_00514 3.42e-41 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HIEBNEHA_00515 1.06e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HIEBNEHA_00516 3.75e-243 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIEBNEHA_00517 2.28e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HIEBNEHA_00518 3.27e-203 - - - EG - - - EamA-like transporter family
HIEBNEHA_00519 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HIEBNEHA_00520 1.04e-69 - - - S - - - Cupredoxin-like domain
HIEBNEHA_00521 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HIEBNEHA_00522 1.5e-111 - - - - - - - -
HIEBNEHA_00524 1.05e-74 - - - - - - - -
HIEBNEHA_00525 4.81e-48 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HIEBNEHA_00526 5.95e-70 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HIEBNEHA_00527 1.15e-123 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HIEBNEHA_00529 4.24e-138 - - - - - - - -
HIEBNEHA_00530 0.0 - - - M - - - domain protein
HIEBNEHA_00531 7.35e-143 - - - M - - - domain protein
HIEBNEHA_00532 6.92e-96 - - - M - - - domain protein
HIEBNEHA_00533 5.04e-74 - - - - - - - -
HIEBNEHA_00534 8.36e-233 ampC - - V - - - Beta-lactamase
HIEBNEHA_00535 1.96e-292 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HIEBNEHA_00536 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HIEBNEHA_00537 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HIEBNEHA_00538 6.57e-296 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
HIEBNEHA_00540 4e-172 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HIEBNEHA_00541 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HIEBNEHA_00542 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HIEBNEHA_00543 9.99e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIEBNEHA_00544 9.99e-213 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIEBNEHA_00545 4.43e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIEBNEHA_00546 2.12e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIEBNEHA_00547 1.35e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIEBNEHA_00548 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIEBNEHA_00549 1.84e-243 yibE - - S - - - overlaps another CDS with the same product name
HIEBNEHA_00550 5.74e-167 yibF - - S - - - overlaps another CDS with the same product name
HIEBNEHA_00551 1.39e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HIEBNEHA_00552 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HIEBNEHA_00553 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIEBNEHA_00554 6.21e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIEBNEHA_00555 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIEBNEHA_00556 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIEBNEHA_00557 4.34e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIEBNEHA_00558 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIEBNEHA_00559 2.11e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HIEBNEHA_00560 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HIEBNEHA_00561 3e-308 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIEBNEHA_00562 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HIEBNEHA_00563 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
HIEBNEHA_00564 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HIEBNEHA_00565 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HIEBNEHA_00566 7.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HIEBNEHA_00567 1.82e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_00568 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00569 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_00571 1.38e-149 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_00572 3.23e-108 uspA - - T - - - universal stress protein
HIEBNEHA_00573 3.61e-61 - - - - - - - -
HIEBNEHA_00574 2.56e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HIEBNEHA_00575 9.66e-110 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HIEBNEHA_00576 9.79e-29 - - - - - - - -
HIEBNEHA_00577 1.36e-96 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HIEBNEHA_00578 6.9e-179 - - - S - - - Membrane
HIEBNEHA_00579 1.34e-177 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HIEBNEHA_00580 2.68e-36 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIEBNEHA_00581 7.63e-132 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIEBNEHA_00582 1.27e-30 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIEBNEHA_00583 6.17e-38 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIEBNEHA_00584 1.56e-47 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIEBNEHA_00585 2.81e-225 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIEBNEHA_00586 1.51e-101 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HIEBNEHA_00587 8.21e-141 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HIEBNEHA_00588 1.69e-102 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HIEBNEHA_00589 2.5e-207 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HIEBNEHA_00590 1.12e-223 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HIEBNEHA_00591 3.99e-81 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HIEBNEHA_00592 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIEBNEHA_00593 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIEBNEHA_00594 7.1e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HIEBNEHA_00595 2.37e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIEBNEHA_00596 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIEBNEHA_00597 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HIEBNEHA_00598 5.45e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HIEBNEHA_00599 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HIEBNEHA_00600 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIEBNEHA_00601 1.81e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HIEBNEHA_00602 9.28e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HIEBNEHA_00603 4.2e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
HIEBNEHA_00604 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HIEBNEHA_00605 3.82e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HIEBNEHA_00606 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HIEBNEHA_00607 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HIEBNEHA_00608 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00609 3.32e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HIEBNEHA_00610 1.87e-288 ymfF - - S - - - Peptidase M16 inactive domain protein
HIEBNEHA_00611 1.92e-316 ymfH - - S - - - Peptidase M16
HIEBNEHA_00612 4.4e-192 - - - S - - - Helix-turn-helix domain
HIEBNEHA_00613 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIEBNEHA_00614 2.97e-285 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HIEBNEHA_00615 2.2e-251 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIEBNEHA_00616 4.62e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HIEBNEHA_00617 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIEBNEHA_00618 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIEBNEHA_00619 4.34e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIEBNEHA_00620 2.74e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIEBNEHA_00621 9.79e-239 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIEBNEHA_00622 1.44e-59 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HIEBNEHA_00623 3.56e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HIEBNEHA_00624 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIEBNEHA_00625 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIEBNEHA_00626 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
HIEBNEHA_00627 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIEBNEHA_00628 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
HIEBNEHA_00629 7.15e-122 cvpA - - S - - - Colicin V production protein
HIEBNEHA_00630 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIEBNEHA_00631 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HIEBNEHA_00632 1.22e-125 yslB - - S - - - Protein of unknown function (DUF2507)
HIEBNEHA_00633 6.89e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HIEBNEHA_00634 4.22e-136 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIEBNEHA_00635 1.65e-120 - - - S ko:K07095 - ko00000 Phosphoesterase
HIEBNEHA_00636 1.21e-98 ykuL - - S - - - (CBS) domain
HIEBNEHA_00637 3.3e-197 - - - S - - - haloacid dehalogenase-like hydrolase
HIEBNEHA_00638 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HIEBNEHA_00639 2.96e-69 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIEBNEHA_00640 4.51e-76 - - - - - - - -
HIEBNEHA_00641 1.98e-166 - - - L - - - Transposase
HIEBNEHA_00642 7.09e-153 - - - L - - - Transposase
HIEBNEHA_00643 7.29e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HIEBNEHA_00644 8.06e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HIEBNEHA_00645 1.1e-176 - - - - - - - -
HIEBNEHA_00646 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
HIEBNEHA_00647 1.34e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HIEBNEHA_00648 1.08e-226 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HIEBNEHA_00649 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HIEBNEHA_00650 1.18e-99 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HIEBNEHA_00651 1.33e-53 - - - - - - - -
HIEBNEHA_00652 7.36e-89 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HIEBNEHA_00654 4.01e-183 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HIEBNEHA_00655 4.36e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIEBNEHA_00656 1.71e-143 - - - S - - - Calcineurin-like phosphoesterase
HIEBNEHA_00657 6.27e-119 yutD - - S - - - Protein of unknown function (DUF1027)
HIEBNEHA_00658 3.91e-169 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIEBNEHA_00659 5.94e-131 - - - S - - - Protein of unknown function (DUF1461)
HIEBNEHA_00660 1.06e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HIEBNEHA_00663 6.36e-75 - - - - - - - -
HIEBNEHA_00683 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00684 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_00687 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00688 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_00690 4e-89 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_00691 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HIEBNEHA_00692 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIEBNEHA_00693 2.13e-152 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIEBNEHA_00694 3.96e-254 coiA - - S ko:K06198 - ko00000 Competence protein
HIEBNEHA_00695 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HIEBNEHA_00696 8.08e-147 yjbH - - Q - - - Thioredoxin
HIEBNEHA_00697 5.87e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HIEBNEHA_00698 1.46e-196 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIEBNEHA_00699 9.29e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HIEBNEHA_00702 6.36e-75 - - - - - - - -
HIEBNEHA_00704 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_00705 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00706 3.85e-139 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00707 9.64e-187 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_00708 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_00710 3.12e-250 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HIEBNEHA_00711 8.76e-201 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HIEBNEHA_00712 3.75e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIEBNEHA_00713 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HIEBNEHA_00714 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
HIEBNEHA_00715 6.9e-77 - - - - - - - -
HIEBNEHA_00716 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HIEBNEHA_00717 2.1e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIEBNEHA_00718 9.94e-73 ftsL - - D - - - Cell division protein FtsL
HIEBNEHA_00719 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HIEBNEHA_00720 7.73e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIEBNEHA_00721 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIEBNEHA_00722 1.98e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIEBNEHA_00723 2.35e-183 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIEBNEHA_00724 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIEBNEHA_00725 8.44e-284 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIEBNEHA_00726 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIEBNEHA_00727 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HIEBNEHA_00728 2.5e-188 ylmH - - S - - - S4 domain protein
HIEBNEHA_00729 8.87e-101 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HIEBNEHA_00730 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIEBNEHA_00731 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HIEBNEHA_00732 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HIEBNEHA_00733 1.19e-25 - - - - - - - -
HIEBNEHA_00734 6.59e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIEBNEHA_00735 1.1e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HIEBNEHA_00736 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HIEBNEHA_00737 8.83e-276 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIEBNEHA_00738 5.71e-159 pgm6 - - G - - - phosphoglycerate mutase
HIEBNEHA_00739 5.21e-155 - - - S - - - repeat protein
HIEBNEHA_00740 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIEBNEHA_00741 3.49e-222 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIEBNEHA_00742 2.6e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIEBNEHA_00743 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HIEBNEHA_00744 9.35e-311 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIEBNEHA_00745 4.39e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIEBNEHA_00746 2.32e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIEBNEHA_00747 1.32e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIEBNEHA_00748 1.56e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIEBNEHA_00749 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_00750 4.47e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIEBNEHA_00751 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HIEBNEHA_00752 1.1e-279 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HIEBNEHA_00753 3.74e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HIEBNEHA_00754 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_00755 2.15e-75 - - - - - - - -
HIEBNEHA_00757 2.51e-217 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HIEBNEHA_00758 4.37e-39 - - - - - - - -
HIEBNEHA_00759 7.16e-231 - - - I - - - Diacylglycerol kinase catalytic
HIEBNEHA_00760 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
HIEBNEHA_00761 3.66e-103 - - - - - - - -
HIEBNEHA_00762 2.78e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIEBNEHA_00763 3.19e-263 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HIEBNEHA_00764 1.34e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HIEBNEHA_00765 1.23e-310 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIEBNEHA_00766 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HIEBNEHA_00767 1.32e-59 yktA - - S - - - Belongs to the UPF0223 family
HIEBNEHA_00768 4.59e-173 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HIEBNEHA_00769 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HIEBNEHA_00770 1.52e-283 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HIEBNEHA_00771 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HIEBNEHA_00772 4.59e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HIEBNEHA_00773 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIEBNEHA_00774 2.03e-250 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HIEBNEHA_00775 4.83e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HIEBNEHA_00776 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HIEBNEHA_00777 9.3e-136 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HIEBNEHA_00778 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HIEBNEHA_00779 2.27e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HIEBNEHA_00780 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HIEBNEHA_00781 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIEBNEHA_00782 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIEBNEHA_00783 3.07e-209 - - - S - - - Tetratricopeptide repeat
HIEBNEHA_00784 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIEBNEHA_00785 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIEBNEHA_00786 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIEBNEHA_00787 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HIEBNEHA_00788 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
HIEBNEHA_00789 2.44e-20 - - - - - - - -
HIEBNEHA_00790 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIEBNEHA_00791 9.78e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIEBNEHA_00792 2.79e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIEBNEHA_00793 2.9e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIEBNEHA_00794 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HIEBNEHA_00795 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIEBNEHA_00796 8.86e-122 - - - - - - - -
HIEBNEHA_00797 1.51e-170 int2 - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_00798 1.47e-23 ansR - - K - - - Transcriptional regulator
HIEBNEHA_00799 3.56e-31 - - - S - - - Helix-turn-helix domain
HIEBNEHA_00800 3.11e-39 - - - - - - - -
HIEBNEHA_00801 3.78e-61 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HIEBNEHA_00803 2.16e-47 - - - V - - - NUMOD4 motif
HIEBNEHA_00809 3.25e-13 - - - L - - - DnaD domain protein
HIEBNEHA_00811 3.49e-89 - - - - - - - -
HIEBNEHA_00813 1.17e-70 - - - - - - - -
HIEBNEHA_00815 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_00816 7.21e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIEBNEHA_00817 1.94e-268 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HIEBNEHA_00818 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIEBNEHA_00819 2.7e-47 ynzC - - S - - - UPF0291 protein
HIEBNEHA_00820 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HIEBNEHA_00821 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HIEBNEHA_00822 5.67e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HIEBNEHA_00823 9.65e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HIEBNEHA_00824 1.62e-230 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIEBNEHA_00825 2.91e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HIEBNEHA_00826 1.82e-196 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIEBNEHA_00827 1.28e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HIEBNEHA_00828 3.48e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIEBNEHA_00829 1.29e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIEBNEHA_00830 5.83e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HIEBNEHA_00831 8.1e-299 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HIEBNEHA_00832 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIEBNEHA_00833 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIEBNEHA_00834 1.67e-66 - - - L - - - Phage integrase family
HIEBNEHA_00837 6.12e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_00838 2.67e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_00843 9.04e-29 - - - S - - - Siphovirus Gp157
HIEBNEHA_00844 7.01e-152 - - - S - - - AAA domain
HIEBNEHA_00845 2.05e-93 - - - - - - - -
HIEBNEHA_00846 0.0 - - - L - - - Helicase C-terminal domain protein
HIEBNEHA_00847 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
HIEBNEHA_00849 6.38e-55 - - - L - - - Endodeoxyribonuclease RusA
HIEBNEHA_00850 1.26e-28 - - - - - - - -
HIEBNEHA_00864 4.73e-180 - - - S - - - Terminase-like family
HIEBNEHA_00865 4.56e-173 - - - S - - - Phage portal protein
HIEBNEHA_00866 3.36e-119 - - - K - - - cell adhesion
HIEBNEHA_00868 3.07e-55 - - - S - - - aminoacyl-tRNA ligase activity
HIEBNEHA_00869 1.02e-123 - - - - - - - -
HIEBNEHA_00870 3.48e-44 - - - S - - - Phage gp6-like head-tail connector protein
HIEBNEHA_00872 2.7e-32 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HIEBNEHA_00873 1.88e-32 - - - S - - - Protein of unknown function (DUF3168)
HIEBNEHA_00874 1.04e-50 - - - S - - - Phage tail tube protein
HIEBNEHA_00875 2.75e-38 - - - S - - - Pfam:Phage_TAC_12
HIEBNEHA_00876 3.47e-37 - - - - - - - -
HIEBNEHA_00877 4.11e-73 - - - D - - - Phage tail tape measure protein, TP901 family
HIEBNEHA_00878 6.42e-98 - - - S - - - phage tail
HIEBNEHA_00879 3.98e-236 - - - M - - - Prophage endopeptidase tail
HIEBNEHA_00880 1.62e-06 - - - - - - - -
HIEBNEHA_00881 4.22e-37 - - - E - - - GDSL-like Lipase/Acylhydrolase
HIEBNEHA_00882 4.7e-74 - - - S - - - Bacteriophage holin family
HIEBNEHA_00883 1.86e-213 - - - M - - - hydrolase, family 25
HIEBNEHA_00885 1.26e-15 - - - - - - - -
HIEBNEHA_00887 6.36e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HIEBNEHA_00888 1.18e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HIEBNEHA_00889 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HIEBNEHA_00890 7.97e-65 ylxQ - - J - - - ribosomal protein
HIEBNEHA_00891 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIEBNEHA_00892 2.79e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIEBNEHA_00893 1.85e-210 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIEBNEHA_00894 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HIEBNEHA_00895 1.04e-83 - - - - - - - -
HIEBNEHA_00896 7.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIEBNEHA_00897 3.69e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIEBNEHA_00898 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HIEBNEHA_00899 1.81e-272 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIEBNEHA_00900 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIEBNEHA_00901 3.74e-287 int7 - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_00902 1.51e-153 - - - V - - - Abi-like protein
HIEBNEHA_00904 1.02e-49 - - - - - - - -
HIEBNEHA_00906 3.95e-29 - - - - - - - -
HIEBNEHA_00910 1.38e-100 - - - K - - - Peptidase S24-like
HIEBNEHA_00911 9.06e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_00916 6.3e-21 - - - - - - - -
HIEBNEHA_00919 3.31e-188 - - - L - - - DnaD domain protein
HIEBNEHA_00920 1.31e-244 - - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_00921 6.93e-161 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HIEBNEHA_00923 9.76e-93 - - - - - - - -
HIEBNEHA_00924 1.62e-173 - - - - - - - -
HIEBNEHA_00931 2.22e-108 - - - S - - - Phage transcriptional regulator, ArpU family
HIEBNEHA_00932 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_00935 8.35e-194 - - - L - - - HNH nucleases
HIEBNEHA_00936 1.39e-101 - - - L - - - Phage terminase, small subunit
HIEBNEHA_00937 0.0 terL - - S - - - overlaps another CDS with the same product name
HIEBNEHA_00939 9.89e-302 - - - S - - - Phage portal protein
HIEBNEHA_00940 3.54e-148 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HIEBNEHA_00941 5.12e-266 - - - S - - - Phage capsid family
HIEBNEHA_00942 8.12e-90 - - - S - - - Phage gp6-like head-tail connector protein
HIEBNEHA_00943 1.34e-55 - - - S - - - Phage head-tail joining protein
HIEBNEHA_00944 1.85e-82 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HIEBNEHA_00945 1.7e-101 - - - - - - - -
HIEBNEHA_00946 1.41e-150 - - - - - - - -
HIEBNEHA_00947 4.31e-76 - - - - - - - -
HIEBNEHA_00948 9.13e-34 - - - - - - - -
HIEBNEHA_00949 0.0 - - - L - - - Phage tail tape measure protein TP901
HIEBNEHA_00950 7.54e-204 - - - S - - - Phage tail protein
HIEBNEHA_00951 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
HIEBNEHA_00953 1.48e-69 - - - S - - - Calcineurin-like phosphoesterase
HIEBNEHA_00959 1.13e-51 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HIEBNEHA_00960 3.21e-247 - - - M - - - hydrolase, family 25
HIEBNEHA_00962 2.52e-109 - - - K - - - IrrE N-terminal-like domain
HIEBNEHA_00963 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HIEBNEHA_00964 2.49e-255 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HIEBNEHA_00966 7.92e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HIEBNEHA_00967 3.36e-77 - - - - - - - -
HIEBNEHA_00968 1.89e-228 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HIEBNEHA_00969 2.17e-161 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIEBNEHA_00970 1.94e-68 - - - - - - - -
HIEBNEHA_00971 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIEBNEHA_00972 7.65e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIEBNEHA_00973 3.62e-212 - - - G - - - Phosphotransferase enzyme family
HIEBNEHA_00974 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIEBNEHA_00975 1.05e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_00976 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HIEBNEHA_00977 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HIEBNEHA_00978 1.35e-91 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HIEBNEHA_00979 5.92e-301 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_00980 5.92e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIEBNEHA_00981 2.07e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIEBNEHA_00982 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HIEBNEHA_00983 3.65e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HIEBNEHA_00984 2.54e-219 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIEBNEHA_00985 2.22e-231 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HIEBNEHA_00986 2.21e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIEBNEHA_00987 1.66e-77 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HIEBNEHA_00988 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIEBNEHA_00989 1.02e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HIEBNEHA_00990 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HIEBNEHA_00991 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HIEBNEHA_00992 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIEBNEHA_00993 1.03e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIEBNEHA_00994 7.19e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_00995 1.27e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HIEBNEHA_00996 1.1e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIEBNEHA_00997 2.61e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HIEBNEHA_00998 3.79e-40 - - - S - - - Protein of unknown function (DUF2929)
HIEBNEHA_00999 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HIEBNEHA_01000 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HIEBNEHA_01001 1.47e-212 yitL - - S ko:K00243 - ko00000 S1 domain
HIEBNEHA_01002 9.16e-209 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HIEBNEHA_01003 1.01e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIEBNEHA_01004 9.25e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIEBNEHA_01005 5.49e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIEBNEHA_01006 3.01e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HIEBNEHA_01007 8.52e-130 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIEBNEHA_01008 1.43e-250 - - - S - - - Helix-turn-helix domain
HIEBNEHA_01009 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HIEBNEHA_01010 1.04e-69 - - - M - - - Lysin motif
HIEBNEHA_01011 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HIEBNEHA_01012 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HIEBNEHA_01013 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HIEBNEHA_01014 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIEBNEHA_01015 7.47e-298 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HIEBNEHA_01016 1.42e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIEBNEHA_01017 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_01018 1.41e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIEBNEHA_01019 1.95e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIEBNEHA_01020 5.85e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HIEBNEHA_01021 1.83e-195 WQ51_01275 - - S - - - EDD domain protein, DegV family
HIEBNEHA_01022 7.3e-216 - - - E - - - lipolytic protein G-D-S-L family
HIEBNEHA_01023 4.73e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HIEBNEHA_01024 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
HIEBNEHA_01025 2.08e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIEBNEHA_01026 5.03e-181 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIEBNEHA_01027 1.07e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HIEBNEHA_01028 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIEBNEHA_01029 5.11e-208 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HIEBNEHA_01030 1.23e-135 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIEBNEHA_01031 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIEBNEHA_01032 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIEBNEHA_01033 1.02e-103 - - - F - - - NUDIX domain
HIEBNEHA_01034 7.36e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HIEBNEHA_01035 2.49e-87 - - - S - - - Belongs to the HesB IscA family
HIEBNEHA_01036 1.96e-35 - - - - - - - -
HIEBNEHA_01038 8.23e-112 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HIEBNEHA_01039 1.57e-80 asp1 - - S - - - Asp23 family, cell envelope-related function
HIEBNEHA_01040 6.23e-35 - - - - - - - -
HIEBNEHA_01041 1.09e-122 - - - - - - - -
HIEBNEHA_01042 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HIEBNEHA_01043 3.28e-232 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HIEBNEHA_01044 1.89e-295 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HIEBNEHA_01045 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HIEBNEHA_01046 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
HIEBNEHA_01047 2.2e-62 - - - - - - - -
HIEBNEHA_01048 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_01049 1.81e-41 - - - - - - - -
HIEBNEHA_01050 7.29e-60 - - - - - - - -
HIEBNEHA_01051 5.53e-127 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HIEBNEHA_01052 0.0 - - - L - - - PLD-like domain
HIEBNEHA_01054 1.41e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01055 8.5e-68 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01056 2.71e-150 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01057 2.9e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HIEBNEHA_01058 2.12e-145 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
HIEBNEHA_01059 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HIEBNEHA_01060 3e-272 - - - G - - - Transporter, major facilitator family protein
HIEBNEHA_01061 5.37e-137 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
HIEBNEHA_01062 9.92e-78 yuxO - - Q - - - Thioesterase superfamily
HIEBNEHA_01063 1.16e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIEBNEHA_01064 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HIEBNEHA_01065 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HIEBNEHA_01066 2.84e-42 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HIEBNEHA_01067 1.56e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HIEBNEHA_01068 2.36e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HIEBNEHA_01069 7.46e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIEBNEHA_01070 1.24e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HIEBNEHA_01071 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HIEBNEHA_01072 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
HIEBNEHA_01073 6.4e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HIEBNEHA_01074 7.15e-148 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HIEBNEHA_01075 1.43e-51 - - - S - - - Cytochrome B5
HIEBNEHA_01076 3.3e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HIEBNEHA_01077 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HIEBNEHA_01078 6.29e-191 - - - O - - - Band 7 protein
HIEBNEHA_01079 5.61e-61 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HIEBNEHA_01080 1.22e-136 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HIEBNEHA_01081 2.76e-151 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HIEBNEHA_01082 1.73e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HIEBNEHA_01083 2.61e-236 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HIEBNEHA_01084 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HIEBNEHA_01085 1.58e-164 - - - L - - - Transposase
HIEBNEHA_01086 1.42e-152 - - - L - - - Transposase
HIEBNEHA_01087 2.78e-118 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HIEBNEHA_01088 3.63e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIEBNEHA_01089 1.13e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HIEBNEHA_01090 8.5e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HIEBNEHA_01091 2.86e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HIEBNEHA_01092 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HIEBNEHA_01093 1.57e-113 ypmB - - S - - - Protein conserved in bacteria
HIEBNEHA_01094 7.96e-158 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HIEBNEHA_01095 2.32e-206 - - - EG - - - EamA-like transporter family
HIEBNEHA_01096 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HIEBNEHA_01097 2.01e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIEBNEHA_01098 4.8e-130 ypsA - - S - - - Belongs to the UPF0398 family
HIEBNEHA_01099 3.25e-72 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIEBNEHA_01100 3.97e-107 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
HIEBNEHA_01101 5.92e-301 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_01102 5.93e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HIEBNEHA_01103 1.55e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HIEBNEHA_01104 7.39e-85 esbA - - S - - - Family of unknown function (DUF5322)
HIEBNEHA_01105 1.26e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIEBNEHA_01106 3.24e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HIEBNEHA_01107 5.29e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HIEBNEHA_01108 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HIEBNEHA_01109 0.0 FbpA - - K - - - Fibronectin-binding protein
HIEBNEHA_01110 5.23e-204 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIEBNEHA_01111 3.45e-206 - - - S - - - EDD domain protein, DegV family
HIEBNEHA_01112 1.18e-120 - - - - - - - -
HIEBNEHA_01113 2.4e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HIEBNEHA_01114 3.03e-195 gspA - - M - - - family 8
HIEBNEHA_01115 5.06e-198 - - - S - - - Alpha beta hydrolase
HIEBNEHA_01116 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
HIEBNEHA_01117 4.27e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HIEBNEHA_01118 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HIEBNEHA_01119 5.56e-214 yvgN - - C - - - Aldo keto reductase
HIEBNEHA_01120 7.79e-204 rlrB - - K - - - LysR substrate binding domain protein
HIEBNEHA_01121 5.42e-105 - - - C - - - Flavodoxin
HIEBNEHA_01122 7.71e-102 - - - S - - - Cupin domain
HIEBNEHA_01123 3.87e-97 - - - S - - - UPF0756 membrane protein
HIEBNEHA_01124 1.18e-308 - - - U - - - Belongs to the major facilitator superfamily
HIEBNEHA_01125 1.68e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HIEBNEHA_01126 1.84e-316 yhdP - - S - - - Transporter associated domain
HIEBNEHA_01127 8.96e-139 ubiB - - S ko:K03688 - ko00000 ABC1 family
HIEBNEHA_01128 1.07e-256 ubiB - - S ko:K03688 - ko00000 ABC1 family
HIEBNEHA_01129 3.01e-185 - - - S - - - DUF218 domain
HIEBNEHA_01130 1.14e-88 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIEBNEHA_01131 4.18e-75 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIEBNEHA_01132 2.56e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIEBNEHA_01133 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HIEBNEHA_01134 2.67e-154 - - - S - - - SNARE associated Golgi protein
HIEBNEHA_01135 7.36e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HIEBNEHA_01136 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIEBNEHA_01139 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HIEBNEHA_01140 4.69e-200 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HIEBNEHA_01141 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIEBNEHA_01142 8.32e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HIEBNEHA_01143 2.26e-94 - - - S - - - Protein of unknown function (DUF3290)
HIEBNEHA_01144 5.93e-149 - - - S - - - Protein of unknown function (DUF421)
HIEBNEHA_01145 6.43e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HIEBNEHA_01146 1.15e-25 - - - - - - - -
HIEBNEHA_01147 8e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HIEBNEHA_01148 5.6e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HIEBNEHA_01149 1.37e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
HIEBNEHA_01150 5.89e-115 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01152 4.22e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
HIEBNEHA_01153 2.05e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_01154 2.06e-208 - - - I - - - alpha/beta hydrolase fold
HIEBNEHA_01155 1.02e-146 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HIEBNEHA_01160 7.67e-251 - - - L - - - Transposase
HIEBNEHA_01165 1.12e-167 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HIEBNEHA_01166 3.64e-175 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HIEBNEHA_01167 1.45e-184 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIEBNEHA_01168 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HIEBNEHA_01169 2.29e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIEBNEHA_01170 4.19e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIEBNEHA_01171 5.28e-281 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIEBNEHA_01172 1.6e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HIEBNEHA_01173 4.93e-197 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HIEBNEHA_01174 1.99e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIEBNEHA_01175 1.12e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIEBNEHA_01176 1.94e-100 - - - K - - - Transcriptional regulator, MarR family
HIEBNEHA_01177 1.39e-91 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIEBNEHA_01179 2.12e-254 xerS - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_01180 5.08e-112 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
HIEBNEHA_01181 3.63e-120 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
HIEBNEHA_01182 1.15e-200 rssA - - S - - - Phospholipase, patatin family
HIEBNEHA_01183 9.45e-152 - - - L - - - Integrase
HIEBNEHA_01184 7.97e-174 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_01185 1.88e-196 - - - EG - - - EamA-like transporter family
HIEBNEHA_01186 5.89e-115 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01187 1.48e-75 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_01188 4.78e-81 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_01189 5.61e-107 - - - L - - - Helix-turn-helix domain
HIEBNEHA_01190 8.9e-111 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HIEBNEHA_01191 4.28e-22 - - - - - - - -
HIEBNEHA_01192 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_01193 2.08e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIEBNEHA_01194 6.12e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HIEBNEHA_01195 5.25e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIEBNEHA_01196 1.13e-291 - - - P - - - Chloride transporter, ClC family
HIEBNEHA_01197 6.64e-51 - - - L - - - PFAM transposase IS116 IS110 IS902
HIEBNEHA_01198 1.77e-92 - - - L - - - PFAM transposase IS116 IS110 IS902
HIEBNEHA_01199 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HIEBNEHA_01200 3.41e-144 - - - I - - - Acid phosphatase homologues
HIEBNEHA_01201 2.9e-203 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_01202 6.61e-80 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_01204 6.36e-75 - - - - - - - -
HIEBNEHA_01206 7.69e-75 - - - - - - - -
HIEBNEHA_01207 3.48e-85 - - - - - - - -
HIEBNEHA_01208 1.29e-37 - - - - - - - -
HIEBNEHA_01209 7.45e-194 - - - G - - - Belongs to the phosphoglycerate mutase family
HIEBNEHA_01210 9.68e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIEBNEHA_01211 1.95e-131 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HIEBNEHA_01212 1.5e-91 - - - - - - - -
HIEBNEHA_01213 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HIEBNEHA_01214 4.61e-133 - - - L - - - nuclease
HIEBNEHA_01215 1.7e-300 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_01216 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HIEBNEHA_01217 1.59e-265 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIEBNEHA_01218 2.39e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HIEBNEHA_01219 0.0 snf - - KL - - - domain protein
HIEBNEHA_01221 1.59e-49 - - - - ko:K18829 - ko00000,ko02048 -
HIEBNEHA_01222 2.08e-88 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
HIEBNEHA_01224 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HIEBNEHA_01225 2.18e-218 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HIEBNEHA_01226 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_01227 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HIEBNEHA_01228 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_01229 5.94e-215 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HIEBNEHA_01231 1.14e-80 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_01232 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_01233 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HIEBNEHA_01234 4.82e-33 - - - S - - - Acyltransferase family
HIEBNEHA_01236 1.42e-59 - - - S - - - Glycosyltransferase like family 2
HIEBNEHA_01237 3.62e-34 - - - S - - - Glycosyltransferase like family 2
HIEBNEHA_01238 1.88e-35 - - - M - - - PFAM Glycosyl transferase family 2
HIEBNEHA_01239 3.36e-35 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HIEBNEHA_01240 1.1e-84 cps2I - - S - - - Psort location CytoplasmicMembrane, score
HIEBNEHA_01242 8e-49 - - - M - - - Glycosyltransferase GT-D fold
HIEBNEHA_01243 5.88e-82 wefC - - M - - - Stealth protein CR2, conserved region 2
HIEBNEHA_01244 1.22e-103 - - GT4 G ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like domain
HIEBNEHA_01245 1.17e-62 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
HIEBNEHA_01246 3.37e-139 ywqD - - D - - - Capsular exopolysaccharide family
HIEBNEHA_01247 7.53e-127 epsB - - M - - - biosynthesis protein
HIEBNEHA_01248 7.67e-132 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01249 5.54e-105 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HIEBNEHA_01250 4.86e-11 - - - C - - - NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
HIEBNEHA_01251 5.12e-252 - - - E ko:K03294 - ko00000 Amino acid permease
HIEBNEHA_01252 5.38e-262 - - - M - - - MobA-like NTP transferase domain
HIEBNEHA_01253 3.86e-131 licC - - M - - - LicC protein
HIEBNEHA_01254 3.08e-121 - - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIEBNEHA_01255 5.43e-58 - - - M ko:K07271 - ko00000,ko01000 LicD family
HIEBNEHA_01256 1.44e-30 - - - S - - - EpsG family
HIEBNEHA_01257 6.09e-61 - - - M - - - Glycosyl transferase, family 2
HIEBNEHA_01258 1.25e-127 gtb - - M - - - transferase activity, transferring glycosyl groups
HIEBNEHA_01259 1.62e-172 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
HIEBNEHA_01260 1.63e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIEBNEHA_01261 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HIEBNEHA_01262 5.74e-206 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIEBNEHA_01263 9.22e-137 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HIEBNEHA_01264 1.09e-151 ywqD - - D - - - Capsular exopolysaccharide family
HIEBNEHA_01265 5.56e-175 epsB - - M - - - biosynthesis protein
HIEBNEHA_01266 4e-216 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HIEBNEHA_01267 3.34e-53 - - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_01268 1.73e-290 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01269 5.18e-40 - - - - - - - -
HIEBNEHA_01270 3.22e-129 - - - K - - - DNA-templated transcription, initiation
HIEBNEHA_01271 1.33e-47 - - - - - - - -
HIEBNEHA_01272 7.88e-116 - - - - - - - -
HIEBNEHA_01273 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIEBNEHA_01274 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HIEBNEHA_01275 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HIEBNEHA_01276 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HIEBNEHA_01277 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HIEBNEHA_01278 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HIEBNEHA_01279 1.13e-191 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIEBNEHA_01280 6.39e-157 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HIEBNEHA_01283 3.97e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01284 1.49e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
HIEBNEHA_01285 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIEBNEHA_01286 2.87e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HIEBNEHA_01287 7.35e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HIEBNEHA_01288 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIEBNEHA_01289 1.01e-108 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HIEBNEHA_01290 6.27e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01291 2.84e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01292 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HIEBNEHA_01293 1.62e-228 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HIEBNEHA_01294 6.71e-151 - - - D - - - transport
HIEBNEHA_01295 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HIEBNEHA_01296 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HIEBNEHA_01297 6.41e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HIEBNEHA_01298 1.86e-14 - - - - - - - -
HIEBNEHA_01299 3.75e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HIEBNEHA_01300 8.66e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HIEBNEHA_01301 1.05e-45 - - - - - - - -
HIEBNEHA_01302 1.27e-105 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_01303 4.31e-158 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_01304 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_01305 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_01307 2.15e-234 - - - M - - - lysozyme activity
HIEBNEHA_01311 0.0 - - - LM - - - gp58-like protein
HIEBNEHA_01312 1.82e-68 - - - - - - - -
HIEBNEHA_01313 0.0 - - - L - - - Phage tail tape measure protein TP901
HIEBNEHA_01314 1.07e-42 - - - - - - - -
HIEBNEHA_01315 3.99e-76 - - - - - - - -
HIEBNEHA_01316 6.52e-94 - - - S - - - Phage tail tube protein, TTP
HIEBNEHA_01317 8.17e-67 - - - - - - - -
HIEBNEHA_01318 9.01e-102 - - - - - - - -
HIEBNEHA_01319 1.63e-75 - - - - - - - -
HIEBNEHA_01320 1.63e-46 - - - - - - - -
HIEBNEHA_01321 2.34e-212 - - - S - - - Phage major capsid protein E
HIEBNEHA_01322 4.08e-71 - - - - - - - -
HIEBNEHA_01323 1.51e-81 - - - S - - - Domain of unknown function (DUF4355)
HIEBNEHA_01324 2.66e-192 - - - S - - - Phage Mu protein F like protein
HIEBNEHA_01325 5.68e-272 - - - S - - - Phage portal protein, SPP1 Gp6-like
HIEBNEHA_01326 1.33e-277 - - - S - - - Terminase-like family
HIEBNEHA_01327 3.82e-163 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
HIEBNEHA_01329 6.17e-79 - - - K - - - Domain of unknown function (DUF4417)
HIEBNEHA_01330 8.36e-09 - - - - - - - -
HIEBNEHA_01339 6.74e-79 rusA - - L - - - Endodeoxyribonuclease RusA
HIEBNEHA_01340 4.72e-27 - - - - - - - -
HIEBNEHA_01341 3.15e-61 - - - S - - - ORF6C domain
HIEBNEHA_01345 1.86e-74 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HIEBNEHA_01346 2.56e-38 - - - K - - - Conserved phage C-terminus (Phg_2220_C)
HIEBNEHA_01347 1.06e-91 - - - S - - - Putative HNHc nuclease
HIEBNEHA_01348 1.41e-46 - - - S - - - Protein of unknown function (DUF669)
HIEBNEHA_01349 2.67e-105 - - - S - - - AAA domain
HIEBNEHA_01350 3.97e-111 - - - S - - - Bacteriophage Mu Gam like protein
HIEBNEHA_01355 1.07e-39 - - - - - - - -
HIEBNEHA_01356 1.11e-26 - - - - - - - -
HIEBNEHA_01358 1.88e-11 - - - - - - - -
HIEBNEHA_01359 2.13e-64 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_01365 5.56e-51 - - - - - - - -
HIEBNEHA_01368 5.55e-66 - - - - - - - -
HIEBNEHA_01369 4.57e-267 - - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_01370 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIEBNEHA_01371 0.0 - - - E ko:K03294 - ko00000 amino acid
HIEBNEHA_01372 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HIEBNEHA_01373 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIEBNEHA_01374 5.32e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HIEBNEHA_01375 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HIEBNEHA_01376 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIEBNEHA_01377 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIEBNEHA_01378 1.61e-259 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIEBNEHA_01379 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HIEBNEHA_01380 6.38e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIEBNEHA_01381 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIEBNEHA_01382 4.72e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIEBNEHA_01383 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIEBNEHA_01384 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HIEBNEHA_01385 2.03e-75 yloU - - S - - - Asp23 family, cell envelope-related function
HIEBNEHA_01386 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HIEBNEHA_01387 4.7e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HIEBNEHA_01388 1.06e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HIEBNEHA_01389 4.03e-207 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIEBNEHA_01390 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HIEBNEHA_01391 1.17e-165 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HIEBNEHA_01392 1.85e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIEBNEHA_01393 7.08e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIEBNEHA_01394 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIEBNEHA_01395 5.9e-262 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIEBNEHA_01396 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIEBNEHA_01397 2.08e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HIEBNEHA_01398 8.66e-70 - - - - - - - -
HIEBNEHA_01399 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HIEBNEHA_01400 1.07e-98 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HIEBNEHA_01401 2.81e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HIEBNEHA_01402 2.49e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HIEBNEHA_01403 1.15e-57 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIEBNEHA_01404 3.95e-280 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIEBNEHA_01405 1.88e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIEBNEHA_01406 1.84e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIEBNEHA_01407 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HIEBNEHA_01408 1.22e-147 - - - J - - - 2'-5' RNA ligase superfamily
HIEBNEHA_01409 4.3e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HIEBNEHA_01410 7.44e-168 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIEBNEHA_01411 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_01412 5.93e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HIEBNEHA_01413 8.44e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HIEBNEHA_01414 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HIEBNEHA_01415 9.45e-145 - - - K - - - Transcriptional regulator
HIEBNEHA_01418 4.54e-111 - - - S - - - Protein conserved in bacteria
HIEBNEHA_01419 1.95e-228 - - - - - - - -
HIEBNEHA_01420 1.39e-202 - - - - - - - -
HIEBNEHA_01421 1.08e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
HIEBNEHA_01422 2.72e-129 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIEBNEHA_01423 1.28e-18 - - - - - - - -
HIEBNEHA_01424 1.7e-50 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_01425 2.07e-40 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_01426 3.18e-122 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIEBNEHA_01427 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIEBNEHA_01428 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HIEBNEHA_01429 5.62e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIEBNEHA_01430 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
HIEBNEHA_01431 1.09e-87 yqhL - - P - - - Rhodanese-like protein
HIEBNEHA_01432 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HIEBNEHA_01433 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HIEBNEHA_01434 7.71e-77 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HIEBNEHA_01435 1.38e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIEBNEHA_01436 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HIEBNEHA_01437 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HIEBNEHA_01438 0.0 - - - S - - - membrane
HIEBNEHA_01439 2.49e-87 yneR - - S - - - Belongs to the HesB IscA family
HIEBNEHA_01440 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIEBNEHA_01441 2.8e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HIEBNEHA_01442 3.97e-102 - - - M - - - PFAM NLP P60 protein
HIEBNEHA_01443 1.47e-33 - - - M - - - PFAM NLP P60 protein
HIEBNEHA_01444 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIEBNEHA_01445 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIEBNEHA_01446 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_01447 7.57e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HIEBNEHA_01448 2.71e-186 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIEBNEHA_01449 2.36e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HIEBNEHA_01450 6.44e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIEBNEHA_01451 1.52e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIEBNEHA_01452 1.24e-296 - - - V - - - MatE
HIEBNEHA_01453 0.0 potE - - E - - - Amino Acid
HIEBNEHA_01454 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIEBNEHA_01455 9.72e-156 csrR - - K - - - response regulator
HIEBNEHA_01456 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HIEBNEHA_01457 8.29e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HIEBNEHA_01458 8.54e-268 ylbM - - S - - - Belongs to the UPF0348 family
HIEBNEHA_01459 5.88e-175 yqeM - - Q - - - Methyltransferase
HIEBNEHA_01460 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIEBNEHA_01461 4.71e-142 yqeK - - H - - - Hydrolase, HD family
HIEBNEHA_01462 4.52e-154 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIEBNEHA_01463 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HIEBNEHA_01464 7.72e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HIEBNEHA_01465 7.47e-123 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HIEBNEHA_01466 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_01467 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_01468 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIEBNEHA_01469 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HIEBNEHA_01470 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIEBNEHA_01471 8.6e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HIEBNEHA_01472 1.1e-297 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HIEBNEHA_01473 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIEBNEHA_01474 1.62e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIEBNEHA_01475 2.16e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIEBNEHA_01476 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIEBNEHA_01477 2.26e-21 - - - S - - - Protein of unknown function (DUF1275)
HIEBNEHA_01478 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HIEBNEHA_01479 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HIEBNEHA_01480 1.99e-153 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIEBNEHA_01481 1.64e-72 ytpP - - CO - - - Thioredoxin
HIEBNEHA_01482 5.37e-74 - - - S - - - Small secreted protein
HIEBNEHA_01483 1.59e-14 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HIEBNEHA_01484 8.08e-76 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HIEBNEHA_01485 6.19e-16 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HIEBNEHA_01486 1.79e-18 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HIEBNEHA_01487 4.37e-23 - - - S - - - YSIRK type signal peptide
HIEBNEHA_01488 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIEBNEHA_01489 1.9e-278 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_01490 3.83e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_01491 8.29e-100 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HIEBNEHA_01493 4.08e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIEBNEHA_01494 0.0 yhaN - - L - - - AAA domain
HIEBNEHA_01495 2.34e-285 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HIEBNEHA_01496 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
HIEBNEHA_01497 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HIEBNEHA_01498 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HIEBNEHA_01499 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HIEBNEHA_01500 2.15e-210 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HIEBNEHA_01502 2.47e-53 - - - - - - - -
HIEBNEHA_01503 1.88e-60 - - - - - - - -
HIEBNEHA_01504 6.22e-266 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HIEBNEHA_01505 1.12e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HIEBNEHA_01506 2.14e-280 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HIEBNEHA_01507 7.92e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HIEBNEHA_01508 1.25e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HIEBNEHA_01509 3.38e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIEBNEHA_01510 4.27e-89 - - - - - - - -
HIEBNEHA_01511 1.99e-182 int2 - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_01512 1.55e-11 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HIEBNEHA_01513 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_01514 5.51e-26 - - - S - - - Helix-turn-helix domain
HIEBNEHA_01515 1.56e-53 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HIEBNEHA_01516 1.53e-06 - - - S - - - Helix-turn-helix domain
HIEBNEHA_01522 5.65e-13 - - - L - - - DnaD domain protein
HIEBNEHA_01525 1.43e-80 - - - - - - - -
HIEBNEHA_01527 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_01529 9.17e-59 - - - - - - - -
HIEBNEHA_01530 1.48e-149 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HIEBNEHA_01531 1.78e-42 - - - - - - - -
HIEBNEHA_01532 8.09e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIEBNEHA_01533 3.58e-238 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HIEBNEHA_01534 1.53e-146 - - - - - - - -
HIEBNEHA_01535 2.52e-149 dgk2 - - F - - - deoxynucleoside kinase
HIEBNEHA_01536 4.69e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIEBNEHA_01537 2.18e-112 - - - T - - - Belongs to the universal stress protein A family
HIEBNEHA_01538 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HIEBNEHA_01539 8.34e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIEBNEHA_01540 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HIEBNEHA_01541 1.77e-56 - - - - - - - -
HIEBNEHA_01542 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HIEBNEHA_01543 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIEBNEHA_01544 7.72e-122 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HIEBNEHA_01545 0.0 - - - EGP - - - Major Facilitator
HIEBNEHA_01546 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HIEBNEHA_01547 2.01e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HIEBNEHA_01548 1.13e-132 - - - V - - - VanZ like family
HIEBNEHA_01549 7.03e-33 - - - - - - - -
HIEBNEHA_01550 1.36e-99 - - - S - - - Short repeat of unknown function (DUF308)
HIEBNEHA_01551 4.4e-101 - - - S - - - Psort location Cytoplasmic, score
HIEBNEHA_01552 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HIEBNEHA_01553 1.55e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HIEBNEHA_01554 2.14e-195 yeaE - - S - - - Aldo keto
HIEBNEHA_01555 5.38e-308 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HIEBNEHA_01556 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HIEBNEHA_01557 5.48e-188 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HIEBNEHA_01558 1.46e-134 - - - M - - - LysM domain protein
HIEBNEHA_01559 0.0 - - - EP - - - Psort location Cytoplasmic, score
HIEBNEHA_01560 5.35e-86 - - - M - - - LysM domain protein
HIEBNEHA_01561 7.16e-201 - - - O - - - Uncharacterized protein family (UPF0051)
HIEBNEHA_01562 3.79e-142 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIEBNEHA_01563 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HIEBNEHA_01564 2.02e-306 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HIEBNEHA_01565 5.19e-127 - - - K - - - Acetyltransferase (GNAT) domain
HIEBNEHA_01567 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HIEBNEHA_01568 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_01578 6.36e-75 - - - - - - - -
HIEBNEHA_01581 5.67e-53 - - - S - - - Protein of unknown function (DUF1797)
HIEBNEHA_01582 9.33e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIEBNEHA_01583 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HIEBNEHA_01584 1.8e-290 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HIEBNEHA_01585 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIEBNEHA_01586 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HIEBNEHA_01587 5.62e-37 - - - - - - - -
HIEBNEHA_01588 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HIEBNEHA_01589 1.82e-129 - - - S - - - Pfam:DUF3816
HIEBNEHA_01590 3.86e-182 - - - G - - - MucBP domain
HIEBNEHA_01591 7.04e-149 - - - - - - - -
HIEBNEHA_01592 3.55e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_01593 7.18e-86 - - - K - - - Transcriptional regulator, GntR family
HIEBNEHA_01594 0.0 - - - S - - - Peptidase, M23
HIEBNEHA_01595 0.0 - - - M - - - NlpC/P60 family
HIEBNEHA_01596 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIEBNEHA_01597 6.84e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HIEBNEHA_01598 3.74e-232 yueF - - S - - - AI-2E family transporter
HIEBNEHA_01599 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
HIEBNEHA_01600 6.42e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIEBNEHA_01601 1.34e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIEBNEHA_01602 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HIEBNEHA_01603 1.58e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIEBNEHA_01604 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIEBNEHA_01605 1.74e-173 - - - - - - - -
HIEBNEHA_01606 4.52e-184 - - - M - - - Glycosyl transferase family 2
HIEBNEHA_01607 2.96e-95 - - - - - - - -
HIEBNEHA_01608 1.14e-89 - - - S - - - Acyltransferase family
HIEBNEHA_01609 4.04e-97 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
HIEBNEHA_01610 1.1e-84 - - - S - - - Glycosyltransferase like family
HIEBNEHA_01611 3.13e-95 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
HIEBNEHA_01612 2.42e-38 - - - M - - - biosynthesis protein
HIEBNEHA_01613 8.66e-108 - - - - - - - -
HIEBNEHA_01614 1.51e-95 - - - M - - - transferase activity, transferring glycosyl groups
HIEBNEHA_01615 8.05e-264 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HIEBNEHA_01616 5.85e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HIEBNEHA_01617 3.83e-39 - - - - - - - -
HIEBNEHA_01618 0.0 - - - G - - - Peptidase_C39 like family
HIEBNEHA_01619 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
HIEBNEHA_01620 4.01e-153 - - - M - - - Bacterial sugar transferase
HIEBNEHA_01621 5.18e-221 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HIEBNEHA_01622 2.23e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
HIEBNEHA_01623 4.55e-172 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HIEBNEHA_01624 8.83e-43 - - - - - - - -
HIEBNEHA_01625 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
HIEBNEHA_01626 3.38e-195 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HIEBNEHA_01627 0.0 potE - - E - - - Amino Acid
HIEBNEHA_01628 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HIEBNEHA_01629 1.97e-280 arcT - - E - - - Aminotransferase
HIEBNEHA_01630 4.08e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HIEBNEHA_01631 9.49e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HIEBNEHA_01632 2.45e-88 gtcA - - S - - - Teichoic acid glycosylation protein
HIEBNEHA_01633 3.98e-15 - - - - - - - -
HIEBNEHA_01634 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIEBNEHA_01636 4.69e-298 yfmL - - L - - - DEAD DEAH box helicase
HIEBNEHA_01637 1.08e-244 mocA - - S - - - Oxidoreductase
HIEBNEHA_01638 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
HIEBNEHA_01639 2.95e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HIEBNEHA_01640 1.86e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HIEBNEHA_01641 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HIEBNEHA_01642 1.6e-246 - - - S - - - Protein of unknown function (DUF3114)
HIEBNEHA_01643 4.36e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HIEBNEHA_01644 2.64e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HIEBNEHA_01645 3.86e-95 - - - P - - - Major Facilitator Superfamily
HIEBNEHA_01646 1.21e-26 - - - - - - - -
HIEBNEHA_01647 1.46e-119 - - - K - - - Acetyltransferase (GNAT) family
HIEBNEHA_01648 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_01649 2.03e-100 - - - K - - - LytTr DNA-binding domain
HIEBNEHA_01650 2.62e-89 - - - S - - - Protein of unknown function (DUF3021)
HIEBNEHA_01651 3.35e-216 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HIEBNEHA_01652 1.52e-108 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HIEBNEHA_01653 7.82e-161 pnb - - C - - - nitroreductase
HIEBNEHA_01654 7.41e-120 - - - - - - - -
HIEBNEHA_01655 5.61e-108 yvbK - - K - - - GNAT family
HIEBNEHA_01656 3.55e-313 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HIEBNEHA_01657 2.44e-266 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HIEBNEHA_01658 1.32e-116 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01659 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_01660 3.18e-133 pncA - - Q - - - Isochorismatase family
HIEBNEHA_01661 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIEBNEHA_01662 8.85e-164 - - - F - - - NUDIX domain
HIEBNEHA_01663 1.27e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIEBNEHA_01664 8.27e-235 - - - S - - - Phage capsid family
HIEBNEHA_01665 1.34e-52 - - - S - - - Phage gp6-like head-tail connector protein
HIEBNEHA_01666 5.85e-73 - - - S - - - Phage head-tail joining protein
HIEBNEHA_01667 5.17e-72 - - - S - - - Bacteriophage holin family
HIEBNEHA_01668 1.13e-26 - - - - - - - -
HIEBNEHA_01669 9.73e-85 - - - L - - - Recombinase zinc beta ribbon domain
HIEBNEHA_01670 3.23e-149 - - - L - - - Recombinase zinc beta ribbon domain
HIEBNEHA_01671 2e-184 - - - L ko:K06400 - ko00000 Recombinase
HIEBNEHA_01672 2.78e-30 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HIEBNEHA_01673 4e-79 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HIEBNEHA_01674 1.9e-107 ung2 - - L - - - Uracil-DNA glycosylase
HIEBNEHA_01675 7.04e-22 ung2 - - L - - - Uracil-DNA glycosylase
HIEBNEHA_01676 5.87e-147 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HIEBNEHA_01677 2.47e-119 dpsB - - P - - - Belongs to the Dps family
HIEBNEHA_01678 3.19e-45 - - - C - - - Heavy-metal-associated domain
HIEBNEHA_01679 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HIEBNEHA_01680 2.48e-178 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_01681 6.98e-137 - - - L - - - Helix-turn-helix domain
HIEBNEHA_01683 0.0 - - - L - - - Helicase C-terminal domain protein
HIEBNEHA_01684 3.96e-61 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HIEBNEHA_01686 2.61e-20 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HIEBNEHA_01687 2.37e-106 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_01688 3.15e-177 - - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_01689 4.25e-90 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HIEBNEHA_01690 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type I restriction enzyme R protein N terminus (HSDR_N)
HIEBNEHA_01691 4.56e-113 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HIEBNEHA_01692 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
HIEBNEHA_01693 4.62e-27 - - - K - - - Cro/C1-type HTH DNA-binding domain
HIEBNEHA_01694 2.54e-145 - - - L - - - Helicase conserved C-terminal domain
HIEBNEHA_01697 2.75e-13 - - - - - - - -
HIEBNEHA_01698 1.78e-14 - - - - - - - -
HIEBNEHA_01699 8.73e-221 - - - L - - - Protein of unknown function (DUF2800)
HIEBNEHA_01700 4.39e-114 - - - S - - - Protein of unknown function (DUF2815)
HIEBNEHA_01701 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
HIEBNEHA_01702 8.88e-52 - - - S - - - Psort location Cytoplasmic, score
HIEBNEHA_01703 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HIEBNEHA_01704 4.75e-43 - - - S - - - VRR_NUC
HIEBNEHA_01705 1.69e-247 - - - L - - - SNF2 family N-terminal domain
HIEBNEHA_01706 3.78e-65 - - - - - - - -
HIEBNEHA_01707 1.4e-73 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
HIEBNEHA_01708 7.99e-120 - - - - - - - -
HIEBNEHA_01709 1.07e-254 - - - KL - - - DNA methylase
HIEBNEHA_01710 6.06e-68 - - - S - - - Psort location Cytoplasmic, score
HIEBNEHA_01711 3.59e-34 - - - S - - - Domain of unknown function (DUF5049)
HIEBNEHA_01712 0.0 - - - S - - - overlaps another CDS with the same product name
HIEBNEHA_01715 1.33e-15 - - - K - - - Antidote-toxin recognition MazE, bacterial antitoxin
HIEBNEHA_01716 2.89e-276 - - - S - - - Phage portal protein
HIEBNEHA_01717 5.25e-104 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HIEBNEHA_01718 5.05e-217 - - - S - - - Phage capsid family
HIEBNEHA_01719 1.93e-42 - - - S - - - Phage gp6-like head-tail connector protein
HIEBNEHA_01720 3.47e-61 - - - S - - - Phage head-tail joining protein
HIEBNEHA_01721 8.23e-68 - - - S - - - Bacteriophage holin family
HIEBNEHA_01722 1.12e-10 - - - - - - - -
HIEBNEHA_01723 3.29e-144 - - - L - - - Recombinase zinc beta ribbon domain
HIEBNEHA_01724 1.09e-08 - - - L ko:K06400 - ko00000 Psort location Cytoplasmic, score
HIEBNEHA_01725 1.39e-248 - - - L ko:K06400 - ko00000 Recombinase
HIEBNEHA_01727 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIEBNEHA_01728 4.7e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HIEBNEHA_01729 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIEBNEHA_01730 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIEBNEHA_01731 9.59e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIEBNEHA_01732 4.51e-260 camS - - S - - - sex pheromone
HIEBNEHA_01733 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIEBNEHA_01734 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HIEBNEHA_01735 4.55e-267 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIEBNEHA_01736 2.75e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIEBNEHA_01737 5.09e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HIEBNEHA_01738 2.58e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HIEBNEHA_01739 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HIEBNEHA_01740 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIEBNEHA_01741 3.54e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIEBNEHA_01742 2.89e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIEBNEHA_01743 3.8e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIEBNEHA_01744 2.96e-178 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIEBNEHA_01745 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HIEBNEHA_01746 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIEBNEHA_01747 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIEBNEHA_01748 2.19e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIEBNEHA_01749 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HIEBNEHA_01750 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIEBNEHA_01751 6.16e-159 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIEBNEHA_01752 9.61e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIEBNEHA_01753 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HIEBNEHA_01754 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HIEBNEHA_01755 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIEBNEHA_01756 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIEBNEHA_01757 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIEBNEHA_01758 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIEBNEHA_01759 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIEBNEHA_01760 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIEBNEHA_01761 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIEBNEHA_01762 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIEBNEHA_01763 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIEBNEHA_01764 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HIEBNEHA_01765 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIEBNEHA_01766 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIEBNEHA_01767 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIEBNEHA_01768 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIEBNEHA_01769 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIEBNEHA_01770 4.22e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIEBNEHA_01771 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HIEBNEHA_01772 7.75e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIEBNEHA_01773 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HIEBNEHA_01774 1.92e-299 isp - - L - - - Transposase
HIEBNEHA_01775 9.65e-175 - - - L ko:K07487 - ko00000 Transposase
HIEBNEHA_01776 7.44e-82 - - - L ko:K07487 - ko00000 Transposase
HIEBNEHA_01777 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIEBNEHA_01778 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIEBNEHA_01779 3.56e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIEBNEHA_01780 1.86e-142 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HIEBNEHA_01781 1.06e-259 - - - - - - - -
HIEBNEHA_01782 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIEBNEHA_01783 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIEBNEHA_01784 8.51e-143 - - - K - - - Bacterial regulatory proteins, tetR family
HIEBNEHA_01785 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIEBNEHA_01786 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HIEBNEHA_01787 2.56e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HIEBNEHA_01788 2e-181 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HIEBNEHA_01789 4.2e-70 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_01795 1.11e-149 dgk2 - - F - - - deoxynucleoside kinase
HIEBNEHA_01796 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HIEBNEHA_01797 1.69e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HIEBNEHA_01798 1.55e-150 - - - I - - - phosphatase
HIEBNEHA_01799 8.68e-106 - - - S - - - Threonine/Serine exporter, ThrE
HIEBNEHA_01800 5.75e-164 - - - S - - - Putative threonine/serine exporter
HIEBNEHA_01801 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HIEBNEHA_01802 3.16e-159 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HIEBNEHA_01803 1.58e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HIEBNEHA_01804 2.99e-151 - - - S - - - membrane
HIEBNEHA_01805 7.81e-141 - - - S - - - VIT family
HIEBNEHA_01806 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
HIEBNEHA_01807 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_01808 5.46e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIEBNEHA_01809 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_01810 1.48e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_01811 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HIEBNEHA_01812 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIEBNEHA_01813 3.88e-73 - - - - - - - -
HIEBNEHA_01814 3.09e-97 - - - K - - - MerR HTH family regulatory protein
HIEBNEHA_01815 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HIEBNEHA_01816 1.26e-158 - - - S - - - Domain of unknown function (DUF4811)
HIEBNEHA_01817 1.84e-204 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HIEBNEHA_01819 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIEBNEHA_01820 3.07e-119 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HIEBNEHA_01821 2.16e-238 - - - I - - - Alpha beta
HIEBNEHA_01822 0.0 qacA - - EGP - - - Major Facilitator
HIEBNEHA_01823 2.6e-150 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HIEBNEHA_01824 0.0 - - - S - - - Putative threonine/serine exporter
HIEBNEHA_01825 1.2e-203 - - - K - - - LysR family
HIEBNEHA_01826 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HIEBNEHA_01827 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HIEBNEHA_01828 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIEBNEHA_01829 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HIEBNEHA_01830 1.44e-202 mleR - - K - - - LysR family
HIEBNEHA_01831 6.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIEBNEHA_01832 7.79e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HIEBNEHA_01833 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
HIEBNEHA_01834 3.51e-212 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01835 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HIEBNEHA_01836 2.33e-29 - - - - - - - -
HIEBNEHA_01837 1.23e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HIEBNEHA_01838 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_01839 2.1e-94 - - - - - - - -
HIEBNEHA_01840 2.79e-294 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HIEBNEHA_01841 3.37e-179 - - - V - - - Beta-lactamase enzyme family
HIEBNEHA_01842 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HIEBNEHA_01843 2.21e-275 - - - EGP - - - Transporter, major facilitator family protein
HIEBNEHA_01844 0.0 arcT - - E - - - Dipeptidase
HIEBNEHA_01845 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HIEBNEHA_01846 1.22e-133 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01847 2.83e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HIEBNEHA_01848 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_01849 6.47e-206 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HIEBNEHA_01850 3.41e-170 - - - I - - - alpha/beta hydrolase fold
HIEBNEHA_01851 2.77e-228 - - - S - - - Conserved hypothetical protein 698
HIEBNEHA_01852 1.44e-121 - - - S - - - NADPH-dependent FMN reductase
HIEBNEHA_01853 1.13e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HIEBNEHA_01854 1.1e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HIEBNEHA_01855 5.18e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HIEBNEHA_01856 2.97e-111 - - - Q - - - Methyltransferase
HIEBNEHA_01857 2.68e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HIEBNEHA_01858 4.77e-305 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HIEBNEHA_01859 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HIEBNEHA_01860 1.33e-179 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HIEBNEHA_01861 1.77e-286 - - - G - - - Glycosyl hydrolases family 8
HIEBNEHA_01862 5.42e-310 - - - M - - - Glycosyl transferase
HIEBNEHA_01863 1.82e-194 - - - - - - - -
HIEBNEHA_01864 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HIEBNEHA_01865 9.02e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIEBNEHA_01866 2.7e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HIEBNEHA_01867 2.77e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HIEBNEHA_01868 1.64e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HIEBNEHA_01869 1.39e-168 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HIEBNEHA_01870 2.07e-24 - - - L - - - Transposase
HIEBNEHA_01871 6.52e-181 - - - L - - - Transposase
HIEBNEHA_01872 4.11e-47 - - - L - - - Transposase
HIEBNEHA_01874 6.97e-240 - - - - - - - -
HIEBNEHA_01875 2.32e-126 - - - K - - - acetyltransferase
HIEBNEHA_01876 5.11e-107 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HIEBNEHA_01877 6.89e-89 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HIEBNEHA_01878 4.41e-70 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIEBNEHA_01879 1.07e-239 - - - - - - - -
HIEBNEHA_01880 3.95e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIEBNEHA_01881 4.41e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HIEBNEHA_01882 1.74e-09 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HIEBNEHA_01884 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HIEBNEHA_01885 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIEBNEHA_01886 2.49e-158 - - - O - - - Zinc-dependent metalloprotease
HIEBNEHA_01887 6.76e-156 - - - L - - - Helix-turn-helix domain
HIEBNEHA_01888 3.02e-103 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HIEBNEHA_01889 1.31e-90 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01890 5.75e-52 - - - S - - - Cytochrome B5
HIEBNEHA_01891 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_01892 1.9e-84 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_01893 3.7e-19 - - - - - - - -
HIEBNEHA_01894 4.2e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HIEBNEHA_01895 3.26e-105 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HIEBNEHA_01896 2.16e-06 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HIEBNEHA_01897 4.04e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01898 2.56e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01899 2.74e-50 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
HIEBNEHA_01900 5.64e-65 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HIEBNEHA_01901 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_01902 2.4e-25 ywlG - - S - - - Belongs to the UPF0340 family
HIEBNEHA_01903 8.12e-204 - - - J - - - Methyltransferase
HIEBNEHA_01904 5.16e-289 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HIEBNEHA_01905 2.19e-44 - - - V - - - DNA restriction-modification system
HIEBNEHA_01906 1.04e-126 - - - V - - - DNA restriction-modification system
HIEBNEHA_01907 4.92e-39 - - - V - - - DNA restriction-modification system
HIEBNEHA_01908 0.0 - - - G - - - Major Facilitator Superfamily
HIEBNEHA_01909 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HIEBNEHA_01910 1.15e-207 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko01000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIEBNEHA_01911 1.64e-233 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HIEBNEHA_01912 0.0 ade - - F - - - Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIEBNEHA_01913 1.23e-93 - - - L - - - Helix-turn-helix domain
HIEBNEHA_01914 7.01e-169 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_01915 6.03e-221 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIEBNEHA_01916 7.19e-229 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HIEBNEHA_01917 1.83e-243 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HIEBNEHA_01918 1.08e-152 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HIEBNEHA_01920 2.61e-77 - - - S ko:K02348 - ko00000 Gnat family
HIEBNEHA_01921 1.26e-137 - - - GM - - - NmrA-like family
HIEBNEHA_01922 1.14e-52 ydeP - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_01923 2.67e-121 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HIEBNEHA_01924 3.45e-90 - - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_01925 6.55e-245 - - - EGP - - - Major Facilitator Superfamily
HIEBNEHA_01927 0.0 sufI - - Q - - - Multicopper oxidase
HIEBNEHA_01929 2.77e-111 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01932 5.15e-114 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_01933 8.32e-104 ydcL - - L - - - Belongs to the 'phage' integrase family
HIEBNEHA_01940 8.49e-230 - - - M - - - Rib/alpha-like repeat
HIEBNEHA_01941 2.14e-37 - - - L ko:K07484 - ko00000 Transposase IS66 family
HIEBNEHA_01945 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HIEBNEHA_01947 1.39e-278 - - - S ko:K07133 - ko00000 cog cog1373
HIEBNEHA_01948 8.32e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HIEBNEHA_01949 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIEBNEHA_01950 1.45e-201 - - - EG - - - EamA-like transporter family
HIEBNEHA_01951 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_01952 3.89e-49 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
HIEBNEHA_01953 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HIEBNEHA_01954 1.9e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HIEBNEHA_01955 6.69e-162 pgm3 - - G - - - phosphoglycerate mutase
HIEBNEHA_01956 7.69e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIEBNEHA_01957 3.69e-45 - - - S - - - Transglycosylase associated protein
HIEBNEHA_01958 6.47e-10 - - - S - - - CsbD-like
HIEBNEHA_01959 1.56e-229 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIEBNEHA_01960 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HIEBNEHA_01961 1.44e-121 - - - K - - - Transcriptional regulator (TetR family)
HIEBNEHA_01962 5.02e-52 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HIEBNEHA_01963 2.21e-191 - - - - - - - -
HIEBNEHA_01964 1.15e-28 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HIEBNEHA_01965 2.03e-105 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HIEBNEHA_01966 1.54e-131 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HIEBNEHA_01967 3.46e-95 - - - F - - - Nudix hydrolase
HIEBNEHA_01968 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HIEBNEHA_01969 3.27e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HIEBNEHA_01970 8.91e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01971 5.74e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01972 8e-39 - - - - - - - -
HIEBNEHA_01973 4.81e-22 - - - - - - - -
HIEBNEHA_01974 1.52e-66 - - - - - - - -
HIEBNEHA_01975 2.03e-141 - - - L - - - Bacterial dnaA protein
HIEBNEHA_01976 1.06e-171 - - - L - - - Integrase core domain
HIEBNEHA_01977 4.88e-42 - - - - - - - -
HIEBNEHA_01978 6.69e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIEBNEHA_01979 7.65e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_01980 1.01e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HIEBNEHA_01981 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIEBNEHA_01982 2.1e-291 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01983 5.74e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01984 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIEBNEHA_01985 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HIEBNEHA_01986 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HIEBNEHA_01987 1.19e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HIEBNEHA_01988 1.56e-222 yagE - - E - - - amino acid
HIEBNEHA_01989 2.14e-148 - - - S - - - HAD hydrolase, family IA, variant
HIEBNEHA_01990 5.17e-24 - - - S - - - PD-(D/E)XK nuclease family transposase
HIEBNEHA_01991 6.92e-70 - - - S - - - PD-(D/E)XK nuclease family transposase
HIEBNEHA_01992 1.91e-43 - - - S - - - PD-(D/E)XK nuclease family transposase
HIEBNEHA_01993 3.99e-232 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HIEBNEHA_01994 1.29e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HIEBNEHA_01995 2.45e-290 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_01996 5.74e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_01997 5.68e-12 - - - IQ - - - KR domain
HIEBNEHA_01998 7.72e-145 - - - IQ - - - KR domain
HIEBNEHA_01999 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
HIEBNEHA_02000 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_02001 3e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HIEBNEHA_02002 2.71e-316 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02003 4.63e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HIEBNEHA_02004 7.6e-70 - - - - - - - -
HIEBNEHA_02005 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HIEBNEHA_02006 2.59e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HIEBNEHA_02007 2.53e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
HIEBNEHA_02008 1.3e-95 - - - K - - - Transcriptional regulator
HIEBNEHA_02009 2.34e-205 - - - - - - - -
HIEBNEHA_02010 6.56e-107 - - - C - - - Zinc-binding dehydrogenase
HIEBNEHA_02011 6.49e-30 - - - C - - - Zinc-binding dehydrogenase
HIEBNEHA_02012 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HIEBNEHA_02013 6.23e-267 - - - EGP - - - Major Facilitator
HIEBNEHA_02014 7.21e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_02015 4.35e-22 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HIEBNEHA_02016 2.31e-11 - - - - - - - -
HIEBNEHA_02017 1.78e-83 - - - - - - - -
HIEBNEHA_02018 2.02e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HIEBNEHA_02019 3.04e-105 uspA3 - - T - - - universal stress protein
HIEBNEHA_02020 0.0 fusA1 - - J - - - elongation factor G
HIEBNEHA_02021 2.96e-211 - - - GK - - - ROK family
HIEBNEHA_02022 9.34e-309 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HIEBNEHA_02023 6.07e-175 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HIEBNEHA_02024 1.83e-99 - - - E - - - amino acid
HIEBNEHA_02025 3.03e-183 - - - E - - - amino acid
HIEBNEHA_02026 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HIEBNEHA_02027 8.56e-162 gntR - - K - - - UbiC transcription regulator-associated domain protein
HIEBNEHA_02028 1.85e-110 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIEBNEHA_02029 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HIEBNEHA_02030 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
HIEBNEHA_02031 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HIEBNEHA_02032 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02033 1.64e-23 - - - K - - - Winged helix-turn-helix DNA-binding
HIEBNEHA_02034 1.86e-227 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIEBNEHA_02035 3.85e-24 - - - S - - - PFAM Archaeal ATPase
HIEBNEHA_02036 4.06e-103 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HIEBNEHA_02037 4.28e-66 - - - S - - - Domain of unknown function (DUF4430)
HIEBNEHA_02038 7.21e-23 - - - EG - - - PFAM EamA-like transporter family
HIEBNEHA_02039 4.7e-21 - - - EG - - - EamA-like transporter family
HIEBNEHA_02040 5.16e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_02041 1.41e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_02042 3.2e-185 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HIEBNEHA_02043 1.1e-91 - - - H - - - Uroporphyrinogen-III synthase
HIEBNEHA_02044 4.47e-95 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HIEBNEHA_02045 2.56e-152 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HIEBNEHA_02046 1.41e-98 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
HIEBNEHA_02047 3.91e-305 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HIEBNEHA_02048 9.66e-224 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
HIEBNEHA_02049 6.56e-174 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HIEBNEHA_02050 6.66e-246 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HIEBNEHA_02051 3.85e-75 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
HIEBNEHA_02052 7.11e-303 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HIEBNEHA_02053 7.19e-155 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
HIEBNEHA_02054 1.88e-131 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HIEBNEHA_02055 8.36e-59 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HIEBNEHA_02056 1.64e-159 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HIEBNEHA_02057 5.52e-117 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HIEBNEHA_02058 1.39e-138 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
HIEBNEHA_02059 1.88e-220 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HIEBNEHA_02060 1.43e-123 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
HIEBNEHA_02061 2.29e-165 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HIEBNEHA_02062 3.13e-181 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
HIEBNEHA_02063 5.75e-165 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HIEBNEHA_02064 7.05e-100 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HIEBNEHA_02065 6.19e-102 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HIEBNEHA_02066 1.39e-244 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HIEBNEHA_02067 4.7e-140 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
HIEBNEHA_02068 4.35e-186 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HIEBNEHA_02069 6.68e-258 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HIEBNEHA_02070 6.95e-216 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
HIEBNEHA_02071 1.72e-102 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HIEBNEHA_02072 3.3e-145 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HIEBNEHA_02073 4.54e-95 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HIEBNEHA_02074 1.44e-90 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
HIEBNEHA_02075 3.45e-87 - - - P - - - Cadmium resistance transporter
HIEBNEHA_02076 1.06e-96 pgm1 - - G - - - phosphoglycerate mutase
HIEBNEHA_02077 1.08e-147 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HIEBNEHA_02078 9.15e-72 - - - E ko:K04031 - ko00000 BMC
HIEBNEHA_02079 1.19e-276 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIEBNEHA_02080 2.5e-258 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
HIEBNEHA_02081 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HIEBNEHA_02082 1.62e-101 pduO - - S - - - Haem-degrading
HIEBNEHA_02083 9.96e-135 - - - S - - - Cobalamin adenosyltransferase
HIEBNEHA_02084 5.63e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HIEBNEHA_02085 1.25e-103 - - - S - - - Putative propanediol utilisation
HIEBNEHA_02086 1.98e-148 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HIEBNEHA_02087 3.65e-53 pduA_2 - - CQ ko:K04027 - ko00000 BMC
HIEBNEHA_02088 2.67e-74 - - - CQ - - - BMC
HIEBNEHA_02089 4.57e-60 pduH - - S - - - Dehydratase medium subunit
HIEBNEHA_02090 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
HIEBNEHA_02091 8.85e-97 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
HIEBNEHA_02092 5e-162 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
HIEBNEHA_02093 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
HIEBNEHA_02094 3.41e-170 pduB - - E - - - BMC
HIEBNEHA_02095 2.33e-50 - - - CQ - - - BMC
HIEBNEHA_02096 1.69e-202 - - - K - - - helix_turn_helix, arabinose operon control protein
HIEBNEHA_02097 4.02e-177 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
HIEBNEHA_02098 9.82e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HIEBNEHA_02099 6.77e-204 - - - - - - - -
HIEBNEHA_02100 8.07e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
HIEBNEHA_02101 1.69e-227 XK27_12525 - - S - - - AI-2E family transporter
HIEBNEHA_02102 7.13e-169 XK27_07210 - - S - - - B3 4 domain
HIEBNEHA_02103 8.16e-103 yybA - - K - - - Transcriptional regulator
HIEBNEHA_02104 5.04e-116 - - - K - - - Domain of unknown function (DUF1836)
HIEBNEHA_02105 9.43e-116 - - - GM - - - epimerase
HIEBNEHA_02106 7.72e-196 - - - V - - - (ABC) transporter
HIEBNEHA_02107 1.53e-303 yhdP - - S - - - Transporter associated domain
HIEBNEHA_02108 1.57e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HIEBNEHA_02109 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HIEBNEHA_02110 7.93e-242 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HIEBNEHA_02111 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIEBNEHA_02112 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIEBNEHA_02113 1.02e-51 - - - - - - - -
HIEBNEHA_02114 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HIEBNEHA_02115 8.55e-291 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HIEBNEHA_02116 5.74e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HIEBNEHA_02117 1.62e-81 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HIEBNEHA_02118 2.65e-56 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HIEBNEHA_02119 2.71e-103 usp5 - - T - - - universal stress protein
HIEBNEHA_02120 2.7e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HIEBNEHA_02121 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIEBNEHA_02122 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_02123 2.19e-134 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HIEBNEHA_02124 1.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HIEBNEHA_02125 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HIEBNEHA_02126 4.92e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIEBNEHA_02127 1.89e-227 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HIEBNEHA_02128 4.49e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HIEBNEHA_02129 9.21e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HIEBNEHA_02130 1.21e-48 - - - - - - - -
HIEBNEHA_02131 1.76e-68 - - - - - - - -
HIEBNEHA_02132 4.14e-257 - - - - - - - -
HIEBNEHA_02133 1.59e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIEBNEHA_02134 2.68e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HIEBNEHA_02135 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_02136 3.44e-200 yvgN - - S - - - Aldo keto reductase
HIEBNEHA_02137 2.51e-160 XK27_10500 - - K - - - response regulator
HIEBNEHA_02138 1.76e-232 kinG - - T - - - Histidine kinase-like ATPases
HIEBNEHA_02139 1.67e-172 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02140 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HIEBNEHA_02141 3.31e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HIEBNEHA_02142 7.55e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HIEBNEHA_02143 7.86e-13 - - - K - - - helix_turn_helix, mercury resistance
HIEBNEHA_02144 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIEBNEHA_02145 1.16e-249 - - - EGP - - - Major Facilitator
HIEBNEHA_02146 2.55e-114 ymdB - - S - - - Macro domain protein
HIEBNEHA_02147 1.51e-137 - - - K - - - Helix-turn-helix XRE-family like proteins
HIEBNEHA_02148 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HIEBNEHA_02149 8.55e-64 - - - - - - - -
HIEBNEHA_02150 2.5e-296 - - - S - - - Putative metallopeptidase domain
HIEBNEHA_02151 1.2e-260 - - - S - - - associated with various cellular activities
HIEBNEHA_02152 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HIEBNEHA_02153 2.01e-84 yeaO - - S - - - Protein of unknown function, DUF488
HIEBNEHA_02155 1.43e-152 yrkL - - S - - - Flavodoxin-like fold
HIEBNEHA_02156 9.17e-70 - - - - - - - -
HIEBNEHA_02158 4.23e-41 - 2.1.1.72 - D ko:K03427 - ko00000,ko01000,ko02048 peptidase
HIEBNEHA_02159 8.04e-63 - - - - - - - -
HIEBNEHA_02160 2.62e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HIEBNEHA_02161 3.92e-288 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HIEBNEHA_02162 7.21e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HIEBNEHA_02163 2.85e-135 - - - NU - - - mannosyl-glycoprotein
HIEBNEHA_02164 3.82e-182 - - - S - - - Putative ABC-transporter type IV
HIEBNEHA_02165 0.0 - - - S - - - ABC transporter, ATP-binding protein
HIEBNEHA_02166 4.15e-23 - - - K - - - Helix-turn-helix domain
HIEBNEHA_02167 1.17e-56 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HIEBNEHA_02168 1.47e-81 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIEBNEHA_02169 1.73e-56 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HIEBNEHA_02170 1.78e-232 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HIEBNEHA_02171 1.31e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIEBNEHA_02172 3.57e-74 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
HIEBNEHA_02173 3.39e-131 cadD - - P - - - Cadmium resistance transporter
HIEBNEHA_02174 2.7e-18 XK27_09155 - - K - - - Transcriptional
HIEBNEHA_02175 3.81e-32 - - - L - - - Integrase
HIEBNEHA_02176 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
HIEBNEHA_02177 5.78e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
HIEBNEHA_02178 5.85e-133 - - - S - - - Protein of unknown function (DUF3278)
HIEBNEHA_02180 4.41e-158 - - - M - - - PFAM NLP P60 protein
HIEBNEHA_02181 8.68e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_02182 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HIEBNEHA_02183 4.63e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02184 6.27e-125 - - - P - - - Cadmium resistance transporter
HIEBNEHA_02185 1.33e-73 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HIEBNEHA_02186 6.64e-297 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HIEBNEHA_02187 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HIEBNEHA_02188 4.41e-168 yceF - - P ko:K05794 - ko00000 membrane
HIEBNEHA_02189 2.09e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HIEBNEHA_02190 3.34e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HIEBNEHA_02191 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HIEBNEHA_02192 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HIEBNEHA_02193 2.22e-312 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HIEBNEHA_02194 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HIEBNEHA_02195 6.61e-91 - 1.1.1.100, 1.1.1.304, 1.1.1.76 - IQ ko:K00059,ko:K18009 ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HIEBNEHA_02196 1.51e-44 - - - K - - - Bacterial transcriptional regulator
HIEBNEHA_02197 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase family
HIEBNEHA_02198 1.7e-54 - - - - - - - -
HIEBNEHA_02199 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIEBNEHA_02200 8.15e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HIEBNEHA_02201 5.92e-301 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_02202 6.21e-82 - - - S - - - Alpha beta hydrolase
HIEBNEHA_02203 4.79e-87 - - - S - - - Alpha beta hydrolase
HIEBNEHA_02204 1.89e-275 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HIEBNEHA_02205 1.46e-126 - - - - - - - -
HIEBNEHA_02207 4.02e-159 - - - M - - - ErfK YbiS YcfS YnhG
HIEBNEHA_02208 0.0 - - - S - - - Putative peptidoglycan binding domain
HIEBNEHA_02209 2.49e-141 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HIEBNEHA_02210 1.42e-112 - - - - - - - -
HIEBNEHA_02211 3.98e-82 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HIEBNEHA_02212 2.11e-193 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HIEBNEHA_02213 2.76e-270 yttB - - EGP - - - Major Facilitator
HIEBNEHA_02214 8.12e-144 - - - - - - - -
HIEBNEHA_02215 2.6e-33 - - - - - - - -
HIEBNEHA_02216 6.54e-222 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HIEBNEHA_02217 4.24e-315 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIEBNEHA_02218 4.71e-121 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_02219 1.76e-191 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_02220 2.02e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HIEBNEHA_02221 1.61e-48 - - - - - - - -
HIEBNEHA_02222 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02223 2.37e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIEBNEHA_02224 7.46e-222 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HIEBNEHA_02225 1.46e-110 - - - K - - - transcriptional regulator (TetR family)
HIEBNEHA_02226 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
HIEBNEHA_02227 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HIEBNEHA_02228 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HIEBNEHA_02229 2.94e-72 - - - - - - - -
HIEBNEHA_02230 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIEBNEHA_02232 3.95e-07 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HIEBNEHA_02233 2.76e-256 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HIEBNEHA_02234 9.51e-127 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HIEBNEHA_02235 6.46e-73 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HIEBNEHA_02236 5.69e-314 - - - E ko:K03294 - ko00000 amino acid
HIEBNEHA_02237 1.1e-152 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIEBNEHA_02239 1.02e-280 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HIEBNEHA_02240 5.92e-301 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_02241 3.33e-39 - - - S - - - Cytochrome B5
HIEBNEHA_02242 4.97e-97 - - - S ko:K02348 - ko00000 Gnat family
HIEBNEHA_02243 1.11e-156 - - - GM - - - NmrA-like family
HIEBNEHA_02244 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_02245 6.45e-138 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HIEBNEHA_02246 1.78e-106 - - - K - - - Transcriptional regulator, HxlR family
HIEBNEHA_02247 2.91e-294 - - - - - - - -
HIEBNEHA_02248 2.65e-269 - - - EGP - - - Major Facilitator Superfamily
HIEBNEHA_02249 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HIEBNEHA_02250 8.37e-145 - - - GM - - - NAD dependent epimerase dehydratase family protein
HIEBNEHA_02251 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HIEBNEHA_02252 1.08e-62 ywnA - - K - - - Transcriptional regulator
HIEBNEHA_02253 5.03e-34 - - - S - - - ECF transporter, substrate-specific component
HIEBNEHA_02254 2.03e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HIEBNEHA_02255 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HIEBNEHA_02256 9.26e-307 isp - - L - - - Transposase
HIEBNEHA_02257 9.8e-156 - - - T - - - Putative diguanylate phosphodiesterase
HIEBNEHA_02258 1.18e-245 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HIEBNEHA_02259 4.06e-108 - - - - - - - -
HIEBNEHA_02260 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HIEBNEHA_02261 3.98e-176 - - - T - - - EAL domain
HIEBNEHA_02262 4.69e-165 - - - F - - - glutamine amidotransferase
HIEBNEHA_02263 3.65e-78 - - - - - - - -
HIEBNEHA_02264 9.48e-128 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HIEBNEHA_02265 6.67e-204 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HIEBNEHA_02266 4.06e-188 - - - K - - - Transcriptional regulator
HIEBNEHA_02267 4.01e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HIEBNEHA_02268 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
HIEBNEHA_02269 1.67e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HIEBNEHA_02270 4.61e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HIEBNEHA_02271 4.88e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HIEBNEHA_02272 2.44e-114 - - - S - - - Alpha beta hydrolase
HIEBNEHA_02273 3.49e-16 - - - S - - - Alpha beta hydrolase
HIEBNEHA_02274 3.1e-170 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HIEBNEHA_02275 3.38e-110 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HIEBNEHA_02276 1.64e-203 lysR - - K - - - Transcriptional regulator
HIEBNEHA_02277 5.96e-32 - - - - - - - -
HIEBNEHA_02278 5.39e-111 - - - C - - - Flavodoxin
HIEBNEHA_02279 3.91e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HIEBNEHA_02280 4.31e-233 - - - C - - - nadph quinone reductase
HIEBNEHA_02281 3.32e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HIEBNEHA_02282 4.64e-143 - - - M - - - Protein of unknown function (DUF3737)
HIEBNEHA_02283 3.74e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HIEBNEHA_02284 1.41e-117 - - - S - - - Peptidase propeptide and YPEB domain
HIEBNEHA_02285 5.45e-282 - - - T - - - GHKL domain
HIEBNEHA_02286 3.12e-151 - - - T - - - Transcriptional regulatory protein, C terminal
HIEBNEHA_02287 4.11e-202 - - - S ko:K07088 - ko00000 Membrane transport protein
HIEBNEHA_02288 3.7e-201 - - - L - - - An automated process has identified a potential problem with this gene model
HIEBNEHA_02289 6.01e-146 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_02290 1.66e-246 flp - - V - - - Beta-lactamase
HIEBNEHA_02291 3.54e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HIEBNEHA_02292 1.09e-127 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HIEBNEHA_02293 4.17e-69 - - - S - - - GyrI-like small molecule binding domain
HIEBNEHA_02294 2.37e-162 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HIEBNEHA_02295 2.36e-172 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HIEBNEHA_02296 5.52e-116 - - - K - - - Bacterial regulatory proteins, tetR family
HIEBNEHA_02297 2.57e-141 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HIEBNEHA_02298 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
HIEBNEHA_02299 4.42e-153 azlC - - E - - - azaleucine resistance protein AzlC
HIEBNEHA_02300 0.0 - - - K - - - Aminotransferase class I and II
HIEBNEHA_02301 4.35e-239 - - - S - - - amidohydrolase
HIEBNEHA_02302 6.56e-147 - - - L ko:K07497 - ko00000 hmm pf00665
HIEBNEHA_02303 3.25e-43 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_02304 1.15e-93 - - - L - - - PFAM Integrase catalytic region
HIEBNEHA_02305 6.71e-61 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HIEBNEHA_02306 5.59e-20 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HIEBNEHA_02307 3.47e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HIEBNEHA_02308 2.51e-33 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_02309 2.03e-141 - - - L - - - Bacterial dnaA protein
HIEBNEHA_02310 1.06e-171 - - - L - - - Integrase core domain
HIEBNEHA_02311 1.77e-256 - - - L - - - transposase IS116 IS110 IS902 family protein
HIEBNEHA_02312 7.33e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HIEBNEHA_02313 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIEBNEHA_02314 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HIEBNEHA_02315 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIEBNEHA_02316 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIEBNEHA_02317 7.3e-169 jag - - S ko:K06346 - ko00000 R3H domain protein
HIEBNEHA_02318 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIEBNEHA_02319 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIEBNEHA_02320 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HIEBNEHA_02321 7.09e-196 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HIEBNEHA_02322 0.0 - - - - - - - -
HIEBNEHA_02324 2.1e-50 - - - K - - - Helix-turn-helix domain
HIEBNEHA_02325 1.48e-68 - - - S - - - Phage derived protein Gp49-like (DUF891)
HIEBNEHA_02326 3.3e-124 - - - L - - - Integrase
HIEBNEHA_02327 1.22e-14 - - - S - - - Domain of unknown function (DUF4145)
HIEBNEHA_02328 1.48e-132 - - - L - - - Transposase and inactivated derivatives, IS30 family
HIEBNEHA_02329 1.27e-58 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HIEBNEHA_02331 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIEBNEHA_02332 3.53e-279 - - - D - - - Domain of Unknown Function (DUF1542)
HIEBNEHA_02333 9.85e-94 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HIEBNEHA_02334 3.67e-16 - - - L - - - Type III restriction/modification enzyme methylation subunit

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)