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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HIENHGCL_00001	6.25e-304	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HIENHGCL_00002	2.45e-214	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
HIENHGCL_00003	1.09e-135	-	-	-	S	-	-	-	Membrane
HIENHGCL_00004	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00005	0.0	-	-	-	G	ko:K02755,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_00006	2.24e-41	-	2.7.1.208, 2.7.1.211	-	G	ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIENHGCL_00007	2.69e-191	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HIENHGCL_00008	0.0	-	-	-	-	-	-	-	-
HIENHGCL_00009	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HIENHGCL_00010	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIENHGCL_00011	5.52e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
HIENHGCL_00012	9.15e-165	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIENHGCL_00013	3.37e-273	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HIENHGCL_00014	3.15e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00015	1.38e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HIENHGCL_00016	3.51e-74	-	-	-	-	-	-	-	-
HIENHGCL_00017	3.26e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIENHGCL_00018	3.19e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIENHGCL_00019	0.0	yhaN	-	-	L	-	-	-	AAA domain
HIENHGCL_00020	8.31e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HIENHGCL_00021	6.93e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HIENHGCL_00022	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HIENHGCL_00023	3.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HIENHGCL_00024	1.34e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIENHGCL_00025	2.79e-154	-	-	-	-	-	-	-	-
HIENHGCL_00026	2.45e-246	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
HIENHGCL_00027	8.56e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HIENHGCL_00028	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HIENHGCL_00029	1.06e-164	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HIENHGCL_00030	1.29e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIENHGCL_00031	3.95e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HIENHGCL_00033	1.19e-71	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HIENHGCL_00034	4.1e-251	flp	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_00035	3.16e-72	-	-	-	-	-	-	-	-
HIENHGCL_00036	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HIENHGCL_00037	4.95e-53	-	-	-	S	-	-	-	Enterocin A Immunity
HIENHGCL_00038	0.0	-	-	-	S	-	-	-	domain, Protein
HIENHGCL_00039	7.05e-89	-	-	-	S	-	-	-	domain, Protein
HIENHGCL_00040	6.41e-105	-	-	-	S	-	-	-	Cupin domain
HIENHGCL_00041	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HIENHGCL_00042	1.39e-22	-	-	-	K	-	-	-	transcriptional regulator
HIENHGCL_00043	3.3e-94	-	-	-	K	-	-	-	transcriptional regulator
HIENHGCL_00045	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIENHGCL_00046	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HIENHGCL_00047	7.75e-153	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HIENHGCL_00048	7.6e-118	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HIENHGCL_00049	1.29e-150	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HIENHGCL_00050	1.37e-36	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HIENHGCL_00051	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_00052	5.35e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIENHGCL_00057	4.65e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HIENHGCL_00058	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HIENHGCL_00059	3.19e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HIENHGCL_00060	1.9e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIENHGCL_00061	6.99e-134	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HIENHGCL_00062	1.91e-135	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HIENHGCL_00063	1.38e-199	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HIENHGCL_00064	2.5e-74	-	-	-	-	-	-	-	-
HIENHGCL_00065	1.62e-211	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HIENHGCL_00066	9.27e-104	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HIENHGCL_00067	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HIENHGCL_00068	4.1e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HIENHGCL_00069	1.37e-74	-	-	-	-	-	-	-	-
HIENHGCL_00070	2.09e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIENHGCL_00071	3.18e-165	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HIENHGCL_00072	1.42e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIENHGCL_00073	1.33e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HIENHGCL_00074	2.57e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HIENHGCL_00075	5.94e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIENHGCL_00076	1.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HIENHGCL_00077	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIENHGCL_00078	2.03e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HIENHGCL_00079	3.27e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIENHGCL_00080	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HIENHGCL_00081	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIENHGCL_00082	8.26e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIENHGCL_00083	9.43e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HIENHGCL_00084	1.32e-255	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIENHGCL_00085	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIENHGCL_00086	2.41e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HIENHGCL_00087	1.61e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIENHGCL_00088	2.35e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIENHGCL_00089	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIENHGCL_00090	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIENHGCL_00091	2.17e-46	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIENHGCL_00092	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIENHGCL_00093	2.22e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIENHGCL_00094	2.29e-175	-	-	-	S	-	-	-	membrane
HIENHGCL_00095	1.33e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIENHGCL_00096	4.92e-107	-	-	-	-	-	-	-	-
HIENHGCL_00097	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_00098	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HIENHGCL_00099	6.41e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIENHGCL_00100	1.24e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIENHGCL_00101	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HIENHGCL_00102	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HIENHGCL_00103	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIENHGCL_00104	1.38e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIENHGCL_00105	4.46e-165	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HIENHGCL_00106	7.2e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIENHGCL_00107	9.05e-170	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIENHGCL_00108	5.62e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIENHGCL_00109	1.49e-138	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HIENHGCL_00110	8.02e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HIENHGCL_00111	6.76e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HIENHGCL_00112	1.29e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HIENHGCL_00113	2.09e-63	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIENHGCL_00114	1.66e-104	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIENHGCL_00115	2.65e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HIENHGCL_00116	5.91e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HIENHGCL_00117	1.85e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HIENHGCL_00118	1.69e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIENHGCL_00119	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HIENHGCL_00120	4.56e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIENHGCL_00121	2.2e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIENHGCL_00122	9.65e-42	-	-	-	K	-	-	-	LysR substrate binding domain
HIENHGCL_00123	3.73e-65	-	-	-	K	-	-	-	LysR substrate binding domain
HIENHGCL_00124	4.38e-74	-	-	-	S	-	-	-	FMN_bind
HIENHGCL_00125	1.87e-292	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HIENHGCL_00126	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HIENHGCL_00127	2.5e-51	-	-	-	S	-	-	-	Cytochrome B5
HIENHGCL_00128	2.27e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HIENHGCL_00129	1.34e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HIENHGCL_00130	1.07e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
HIENHGCL_00131	6.45e-204	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HIENHGCL_00132	1.11e-191	-	-	-	I	-	-	-	Acyl-transferase
HIENHGCL_00133	8.36e-102	-	-	-	-	-	-	-	-
HIENHGCL_00134	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HIENHGCL_00135	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_00137	9.77e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HIENHGCL_00138	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HIENHGCL_00139	0.0	yycH	-	-	S	-	-	-	YycH protein
HIENHGCL_00140	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
HIENHGCL_00141	9.1e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HIENHGCL_00142	2.7e-257	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HIENHGCL_00143	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIENHGCL_00144	4.72e-152	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_00146	0.0	-	-	-	S	-	-	-	CAAX protease self-immunity
HIENHGCL_00147	1.98e-26	-	-	-	-	-	-	-	-
HIENHGCL_00148	1.09e-157	-	-	-	-	-	-	-	-
HIENHGCL_00149	8e-226	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HIENHGCL_00150	6.92e-130	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HIENHGCL_00151	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00152	2.11e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIENHGCL_00153	9.9e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HIENHGCL_00154	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HIENHGCL_00155	4.01e-218	ysdE	-	-	P	-	-	-	Citrate transporter
HIENHGCL_00156	3.96e-05	ysdE	-	-	P	-	-	-	Citrate transporter
HIENHGCL_00157	7.83e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HIENHGCL_00158	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HIENHGCL_00159	9.69e-25	-	-	-	-	-	-	-	-
HIENHGCL_00160	6.75e-127	-	-	-	-	-	-	-	-
HIENHGCL_00161	4.99e-47	-	-	-	-	-	-	-	-
HIENHGCL_00163	1.08e-288	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HIENHGCL_00164	2.11e-271	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HIENHGCL_00165	1.07e-157	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HIENHGCL_00166	2.73e-206	-	-	-	L	-	-	-	HNH nucleases
HIENHGCL_00167	1.63e-233	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HIENHGCL_00168	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00169	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_00170	3.08e-159	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HIENHGCL_00171	2.29e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HIENHGCL_00172	9.33e-180	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HIENHGCL_00173	2.69e-72	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HIENHGCL_00174	2.57e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HIENHGCL_00175	9.36e-111	-	-	-	-	-	-	-	-
HIENHGCL_00176	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIENHGCL_00177	1.45e-231	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HIENHGCL_00178	1.58e-172	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIENHGCL_00179	5.06e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HIENHGCL_00180	2.63e-204	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIENHGCL_00181	1.07e-163	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HIENHGCL_00182	1.02e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_00183	1.33e-75	-	-	-	-	-	-	-	-
HIENHGCL_00184	2.83e-62	-	-	-	-	-	-	-	-
HIENHGCL_00185	1.3e-99	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIENHGCL_00186	1.51e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIENHGCL_00187	1.97e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIENHGCL_00188	2.93e-173	-	-	-	-	-	-	-	-
HIENHGCL_00189	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HIENHGCL_00190	7.42e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00191	1.96e-293	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HIENHGCL_00192	7.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HIENHGCL_00193	1.49e-136	-	-	-	-	-	-	-	-
HIENHGCL_00194	1.62e-256	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HIENHGCL_00195	1.71e-170	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HIENHGCL_00196	7.56e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIENHGCL_00197	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HIENHGCL_00198	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIENHGCL_00199	2.9e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HIENHGCL_00200	1.74e-112	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIENHGCL_00201	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIENHGCL_00202	5.61e-113	usp5	-	-	T	-	-	-	universal stress protein
HIENHGCL_00203	7.56e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HIENHGCL_00204	4.46e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HIENHGCL_00205	2.84e-171	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_00206	6.38e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_00207	7.66e-141	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HIENHGCL_00208	3.65e-109	-	-	-	-	-	-	-	-
HIENHGCL_00209	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIENHGCL_00210	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HIENHGCL_00211	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HIENHGCL_00212	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HIENHGCL_00213	1.29e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIENHGCL_00214	1.6e-127	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HIENHGCL_00215	4.3e-297	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HIENHGCL_00216	1.88e-292	yttB	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_00217	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HIENHGCL_00218	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HIENHGCL_00219	6.3e-91	-	-	-	-	-	-	-	-
HIENHGCL_00220	2.15e-21	-	-	-	-	-	-	-	-
HIENHGCL_00221	9.97e-103	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HIENHGCL_00222	4.63e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIENHGCL_00223	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_00224	5.47e-199	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HIENHGCL_00225	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
HIENHGCL_00226	1.05e-225	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HIENHGCL_00227	8.27e-190	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIENHGCL_00228	2.7e-10	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIENHGCL_00229	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HIENHGCL_00230	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIENHGCL_00231	1.11e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIENHGCL_00232	0.0	-	-	-	G	-	-	-	isomerase
HIENHGCL_00233	1.46e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HIENHGCL_00234	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HIENHGCL_00235	8.15e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HIENHGCL_00236	1.79e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIENHGCL_00237	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
HIENHGCL_00238	1.05e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HIENHGCL_00239	2.88e-223	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIENHGCL_00240	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain
HIENHGCL_00241	3.89e-77	-	-	-	G	-	-	-	polysaccharide catabolic process
HIENHGCL_00242	1.99e-99	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIENHGCL_00243	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIENHGCL_00244	5.29e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HIENHGCL_00245	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIENHGCL_00246	5.18e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIENHGCL_00247	1.5e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HIENHGCL_00248	2.24e-284	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HIENHGCL_00271	3.83e-61	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HIENHGCL_00272	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HIENHGCL_00273	1.98e-96	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HIENHGCL_00278	5.77e-307	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HIENHGCL_00279	4.48e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIENHGCL_00280	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HIENHGCL_00281	1.12e-228	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIENHGCL_00282	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIENHGCL_00283	1.16e-88	-	-	-	-	-	-	-	-
HIENHGCL_00284	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HIENHGCL_00285	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIENHGCL_00286	1.9e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIENHGCL_00287	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HIENHGCL_00288	1.07e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIENHGCL_00289	5.01e-164	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HIENHGCL_00290	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIENHGCL_00291	2.48e-91	-	-	-	S	-	-	-	GtrA-like protein
HIENHGCL_00292	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HIENHGCL_00293	2.58e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HIENHGCL_00294	1.19e-156	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HIENHGCL_00295	1.4e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HIENHGCL_00296	2.83e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIENHGCL_00297	2.97e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
HIENHGCL_00298	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HIENHGCL_00299	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_00300	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_00301	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HIENHGCL_00302	9.32e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HIENHGCL_00303	1.59e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HIENHGCL_00304	6.34e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HIENHGCL_00305	2.05e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HIENHGCL_00306	1.45e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIENHGCL_00307	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HIENHGCL_00308	2.53e-114	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIENHGCL_00309	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIENHGCL_00310	1.89e-188	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HIENHGCL_00311	1.35e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HIENHGCL_00312	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIENHGCL_00313	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIENHGCL_00314	2.39e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HIENHGCL_00315	3.76e-268	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HIENHGCL_00316	6.47e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HIENHGCL_00317	3.95e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HIENHGCL_00318	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIENHGCL_00319	9.65e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIENHGCL_00320	8.54e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIENHGCL_00321	2.49e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HIENHGCL_00322	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HIENHGCL_00323	2.1e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIENHGCL_00324	7.55e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIENHGCL_00325	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HIENHGCL_00326	5.85e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIENHGCL_00327	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIENHGCL_00328	6.07e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HIENHGCL_00329	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HIENHGCL_00330	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIENHGCL_00331	7.02e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIENHGCL_00333	6.15e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIENHGCL_00334	1.72e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HIENHGCL_00335	1.73e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HIENHGCL_00336	4.53e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HIENHGCL_00337	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIENHGCL_00338	1.19e-113	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
HIENHGCL_00339	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HIENHGCL_00340	2.3e-100	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HIENHGCL_00341	1.32e-90	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HIENHGCL_00342	4.54e-95	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HIENHGCL_00343	3.83e-127	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HIENHGCL_00344	3.35e-291	-	-	-	S	-	-	-	Sterol carrier protein domain
HIENHGCL_00345	8.62e-22	-	-	-	-	-	-	-	-
HIENHGCL_00346	1.82e-139	-	-	-	K	-	-	-	LysR substrate binding domain
HIENHGCL_00347	8.29e-129	-	-	-	-	-	-	-	-
HIENHGCL_00348	3.69e-157	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HIENHGCL_00349	0.0	-	-	-	-	-	-	-	-
HIENHGCL_00350	5.4e-282	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HIENHGCL_00351	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HIENHGCL_00352	2.86e-05	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
HIENHGCL_00353	0.0	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
HIENHGCL_00354	1.92e-141	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HIENHGCL_00355	3.65e-28	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HIENHGCL_00356	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIENHGCL_00357	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HIENHGCL_00358	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HIENHGCL_00359	1.58e-282	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HIENHGCL_00360	4.04e-207	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIENHGCL_00361	1.4e-157	-	-	-	-	-	-	-	-
HIENHGCL_00362	2.17e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIENHGCL_00363	6.31e-144	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIENHGCL_00364	3.22e-133	-	-	-	S	-	-	-	Peptidase family M23
HIENHGCL_00365	2.71e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIENHGCL_00366	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HIENHGCL_00367	4.38e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HIENHGCL_00368	1.82e-226	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HIENHGCL_00369	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIENHGCL_00370	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIENHGCL_00371	5.41e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HIENHGCL_00372	1.05e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HIENHGCL_00373	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HIENHGCL_00374	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIENHGCL_00375	3.01e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIENHGCL_00376	2.24e-162	-	-	-	S	-	-	-	Peptidase family M23
HIENHGCL_00377	1.87e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HIENHGCL_00378	4.48e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HIENHGCL_00379	3.45e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIENHGCL_00380	7.64e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HIENHGCL_00381	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HIENHGCL_00382	1.09e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIENHGCL_00383	1.51e-174	-	-	-	-	-	-	-	-
HIENHGCL_00384	2.03e-186	-	-	-	-	-	-	-	-
HIENHGCL_00385	3.64e-175	-	-	-	-	-	-	-	-
HIENHGCL_00386	1.04e-37	-	-	-	-	-	-	-	-
HIENHGCL_00387	1.72e-123	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HIENHGCL_00388	1.57e-181	-	-	-	-	-	-	-	-
HIENHGCL_00389	1.05e-228	-	-	-	-	-	-	-	-
HIENHGCL_00390	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HIENHGCL_00391	1.14e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HIENHGCL_00392	2.04e-73	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIENHGCL_00393	1.18e-140	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIENHGCL_00394	1.01e-187	-	-	-	K	-	-	-	SIS domain
HIENHGCL_00395	2.09e-242	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIENHGCL_00396	1.64e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HIENHGCL_00397	3.39e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HIENHGCL_00398	6.78e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HIENHGCL_00399	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIENHGCL_00400	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HIENHGCL_00401	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HIENHGCL_00402	8.23e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HIENHGCL_00403	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HIENHGCL_00404	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HIENHGCL_00405	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIENHGCL_00406	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HIENHGCL_00407	1.99e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIENHGCL_00408	1.61e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HIENHGCL_00409	2.83e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIENHGCL_00410	2.39e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HIENHGCL_00411	2.01e-310	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIENHGCL_00412	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HIENHGCL_00413	6.03e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIENHGCL_00414	2.88e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HIENHGCL_00415	2.05e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HIENHGCL_00416	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HIENHGCL_00417	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HIENHGCL_00418	2.95e-87	-	-	-	-	-	-	-	-
HIENHGCL_00419	7.03e-104	-	-	-	S	-	-	-	EDD domain protein, DegV family
HIENHGCL_00420	7.16e-71	-	-	-	S	-	-	-	EDD domain protein, DegV family
HIENHGCL_00421	5.95e-250	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HIENHGCL_00422	1.03e-100	-	-	-	-	-	-	-	-
HIENHGCL_00423	1.27e-119	flaR	-	-	F	-	-	-	topology modulation protein
HIENHGCL_00424	2.62e-138	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
HIENHGCL_00425	2.71e-256	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIENHGCL_00426	3.43e-07	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIENHGCL_00427	3.92e-76	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIENHGCL_00428	1.06e-110	rmaD	-	-	K	-	-	-	transcriptional
HIENHGCL_00429	1.74e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HIENHGCL_00430	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_00431	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_00433	3.46e-87	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HIENHGCL_00434	4.78e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HIENHGCL_00435	9.73e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
HIENHGCL_00436	7.02e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIENHGCL_00437	3.65e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HIENHGCL_00438	6.17e-236	-	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_00439	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIENHGCL_00440	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIENHGCL_00441	1.9e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIENHGCL_00442	1.17e-130	-	-	-	-	-	-	-	-
HIENHGCL_00443	8.53e-215	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HIENHGCL_00444	1.43e-24	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HIENHGCL_00445	4.13e-18	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIENHGCL_00446	6e-59	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIENHGCL_00447	1.37e-15	-	-	-	S	-	-	-	Alpha beta hydrolase
HIENHGCL_00448	0.0	yagE	-	-	E	-	-	-	amino acid
HIENHGCL_00450	2.54e-101	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HIENHGCL_00451	1.39e-190	-	-	-	P	-	-	-	FAD-binding domain
HIENHGCL_00452	3.1e-30	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_00453	7.38e-127	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HIENHGCL_00454	1.29e-182	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_00455	3.77e-32	-	-	-	-	-	-	-	-
HIENHGCL_00456	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HIENHGCL_00457	2.88e-130	-	-	-	P	-	-	-	esterase
HIENHGCL_00458	9.87e-139	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_00460	1.51e-24	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_00461	1.54e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
HIENHGCL_00462	7.12e-80	-	-	-	C	-	-	-	aldo keto reductase
HIENHGCL_00463	1.16e-148	-	-	-	C	-	-	-	Aldo/keto reductase family
HIENHGCL_00464	3.78e-72	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HIENHGCL_00465	1.57e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HIENHGCL_00466	4.35e-108	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HIENHGCL_00467	2.29e-224	yobV3	-	-	K	-	-	-	WYL domain
HIENHGCL_00468	0.0	-	-	-	-	-	-	-	-
HIENHGCL_00469	0.0	-	-	-	-	-	-	-	-
HIENHGCL_00470	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate carboxylase activity
HIENHGCL_00471	3.16e-190	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HIENHGCL_00472	6.01e-54	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HIENHGCL_00473	4.4e-138	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HIENHGCL_00474	4.76e-306	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HIENHGCL_00475	2.81e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HIENHGCL_00476	2.51e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HIENHGCL_00477	2.55e-118	-	-	-	L	-	-	-	nuclease
HIENHGCL_00478	3.03e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIENHGCL_00479	1.23e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HIENHGCL_00480	5.33e-147	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HIENHGCL_00481	2.27e-248	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIENHGCL_00482	2.2e-310	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HIENHGCL_00483	3.74e-130	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HIENHGCL_00484	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HIENHGCL_00485	3.77e-216	mleR	-	-	K	-	-	-	LysR family
HIENHGCL_00486	8.78e-52	-	-	-	-	-	-	-	-
HIENHGCL_00487	9.6e-137	-	-	-	-	-	-	-	-
HIENHGCL_00488	2.58e-67	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HIENHGCL_00489	1.24e-47	-	-	-	-	-	-	-	-
HIENHGCL_00490	1.79e-144	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HIENHGCL_00491	2.55e-64	-	-	-	F	-	-	-	Phosphorylase superfamily
HIENHGCL_00492	5.98e-108	-	-	-	F	-	-	-	Phosphorylase superfamily
HIENHGCL_00493	2.07e-189	-	-	-	F	-	-	-	Phosphorylase superfamily
HIENHGCL_00494	3.34e-139	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HIENHGCL_00495	2.72e-188	-	-	-	F	-	-	-	Phosphorylase superfamily
HIENHGCL_00496	1.22e-103	-	-	-	-	-	-	-	-
HIENHGCL_00497	6.2e-131	-	-	-	-	-	-	-	-
HIENHGCL_00498	1.62e-135	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HIENHGCL_00499	4.91e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIENHGCL_00500	5.21e-82	-	-	-	-	-	-	-	-
HIENHGCL_00501	1.24e-113	-	-	-	FG	-	-	-	HIT domain
HIENHGCL_00502	2.43e-100	-	-	-	-	-	-	-	-
HIENHGCL_00503	2.53e-152	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HIENHGCL_00504	1.7e-199	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HIENHGCL_00505	9.73e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIENHGCL_00506	3.18e-167	-	-	-	F	-	-	-	glutamine amidotransferase
HIENHGCL_00507	3.18e-140	-	-	-	-	-	-	-	-
HIENHGCL_00508	1.41e-141	-	-	-	-	-	-	-	-
HIENHGCL_00509	5.1e-43	-	-	-	-	-	-	-	-
HIENHGCL_00510	1.81e-223	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HIENHGCL_00511	1.72e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIENHGCL_00512	2.66e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIENHGCL_00513	3.59e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_00514	6.13e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00515	2.48e-131	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HIENHGCL_00516	3.25e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HIENHGCL_00517	4.2e-42	lysR	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_00518	1.13e-219	-	-	-	-	-	-	-	-
HIENHGCL_00519	3.34e-211	-	-	-	S	-	-	-	reductase
HIENHGCL_00520	8.07e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HIENHGCL_00521	2.07e-102	-	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_00522	2.77e-134	-	-	-	-	-	-	-	-
HIENHGCL_00525	1.7e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIENHGCL_00526	5.42e-275	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_00527	1.31e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
HIENHGCL_00528	1.08e-212	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HIENHGCL_00529	2.55e-214	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HIENHGCL_00530	5.96e-205	-	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_00531	5.93e-149	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HIENHGCL_00532	1.72e-208	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
HIENHGCL_00533	9.5e-39	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HIENHGCL_00534	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIENHGCL_00535	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIENHGCL_00536	2.61e-19	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIENHGCL_00537	7.57e-211	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HIENHGCL_00538	5.84e-129	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIENHGCL_00539	5.68e-165	-	-	-	M	-	-	-	Glycosyl transferases group 1
HIENHGCL_00540	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HIENHGCL_00541	2.78e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HIENHGCL_00542	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_00543	9.84e-146	-	-	-	-	-	-	-	-
HIENHGCL_00544	7.54e-128	-	-	-	-	-	-	-	-
HIENHGCL_00545	1.84e-281	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HIENHGCL_00546	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HIENHGCL_00547	2.42e-201	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HIENHGCL_00548	1.71e-265	-	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_00549	5.22e-89	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIENHGCL_00550	8.43e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
HIENHGCL_00551	4.33e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HIENHGCL_00552	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HIENHGCL_00553	1.47e-105	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_00554	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HIENHGCL_00555	7.3e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HIENHGCL_00556	6.35e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HIENHGCL_00557	1.13e-312	ynbB	-	-	P	-	-	-	aluminum resistance
HIENHGCL_00558	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HIENHGCL_00559	0.0	-	-	-	E	-	-	-	Amino acid permease
HIENHGCL_00560	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HIENHGCL_00561	9.18e-83	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIENHGCL_00562	7.42e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIENHGCL_00563	2.82e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HIENHGCL_00564	1.25e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HIENHGCL_00565	4.82e-296	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_00566	1.72e-85	-	-	-	-	-	-	-	-
HIENHGCL_00567	3.4e-230	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HIENHGCL_00568	4.61e-308	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIENHGCL_00569	3.29e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIENHGCL_00570	2.27e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HIENHGCL_00571	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIENHGCL_00572	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIENHGCL_00573	1.07e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HIENHGCL_00574	8.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIENHGCL_00575	8.81e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIENHGCL_00576	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HIENHGCL_00577	1.64e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HIENHGCL_00578	1.34e-77	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HIENHGCL_00579	1.31e-96	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HIENHGCL_00580	4.94e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HIENHGCL_00581	8.15e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIENHGCL_00582	1.3e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIENHGCL_00583	2.22e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HIENHGCL_00584	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIENHGCL_00585	3.15e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HIENHGCL_00586	4.07e-270	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HIENHGCL_00587	1.28e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HIENHGCL_00588	7.33e-71	-	-	-	M	-	-	-	Lysin motif
HIENHGCL_00589	1.25e-105	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIENHGCL_00590	2.1e-18	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIENHGCL_00591	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HIENHGCL_00592	5.75e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIENHGCL_00593	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIENHGCL_00594	6.56e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIENHGCL_00595	2.19e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HIENHGCL_00596	1e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HIENHGCL_00597	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HIENHGCL_00598	7.76e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIENHGCL_00599	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HIENHGCL_00600	3.9e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HIENHGCL_00601	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HIENHGCL_00602	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HIENHGCL_00603	2.25e-45	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HIENHGCL_00604	1.5e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HIENHGCL_00605	6.35e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIENHGCL_00606	6.51e-113	oatA	-	-	I	-	-	-	Acyltransferase
HIENHGCL_00607	9.21e-273	oatA	-	-	I	-	-	-	Acyltransferase
HIENHGCL_00608	3.01e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIENHGCL_00609	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIENHGCL_00610	4.52e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HIENHGCL_00611	5.04e-298	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HIENHGCL_00612	2.31e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIENHGCL_00613	3.29e-193	yxeH	-	-	S	-	-	-	hydrolase
HIENHGCL_00614	2.72e-197	-	-	-	S	-	-	-	reductase
HIENHGCL_00615	1.03e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIENHGCL_00616	9.94e-287	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HIENHGCL_00617	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIENHGCL_00618	1.74e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HIENHGCL_00619	2.56e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIENHGCL_00620	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIENHGCL_00621	1.17e-65	-	-	-	-	-	-	-	-
HIENHGCL_00622	1.54e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HIENHGCL_00623	1.88e-111	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIENHGCL_00624	3.82e-312	-	-	-	S	-	-	-	Putative threonine/serine exporter
HIENHGCL_00625	1.56e-228	citR	-	-	K	-	-	-	Putative sugar-binding domain
HIENHGCL_00626	5.21e-71	-	-	-	-	-	-	-	-
HIENHGCL_00627	2.09e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HIENHGCL_00628	4.42e-124	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HIENHGCL_00629	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_00630	7.06e-166	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HIENHGCL_00631	6.03e-19	-	-	-	-	-	-	-	-
HIENHGCL_00632	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HIENHGCL_00633	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HIENHGCL_00634	6.24e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HIENHGCL_00635	2.76e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HIENHGCL_00636	7.35e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HIENHGCL_00637	7.54e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HIENHGCL_00638	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HIENHGCL_00639	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIENHGCL_00640	5.14e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HIENHGCL_00641	0.0	-	-	-	M	-	-	-	domain protein
HIENHGCL_00642	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HIENHGCL_00643	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIENHGCL_00644	4.45e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_00645	1.74e-199	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIENHGCL_00646	1.03e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HIENHGCL_00647	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HIENHGCL_00648	1.53e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIENHGCL_00649	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIENHGCL_00650	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIENHGCL_00651	2.16e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_00652	9.27e-75	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HIENHGCL_00653	0.000281	-	-	-	-	-	-	-	-
HIENHGCL_00654	4.66e-128	-	-	-	-	-	-	-	-
HIENHGCL_00655	1.09e-34	-	-	-	-	-	-	-	-
HIENHGCL_00656	2.59e-229	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIENHGCL_00658	5.99e-244	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIENHGCL_00659	2.64e-128	-	-	-	I	-	-	-	PAP2 superfamily
HIENHGCL_00660	1.19e-194	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HIENHGCL_00661	2.12e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIENHGCL_00662	4.93e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HIENHGCL_00663	1.01e-111	yfhC	-	-	C	-	-	-	Nitroreductase family
HIENHGCL_00664	3.69e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIENHGCL_00665	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00666	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_00667	1.91e-55	-	-	-	-	-	-	-	-
HIENHGCL_00668	1.53e-139	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HIENHGCL_00669	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00670	2.84e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HIENHGCL_00671	1.68e-179	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_00672	4.68e-104	-	-	-	-	-	-	-	-
HIENHGCL_00673	4.75e-80	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HIENHGCL_00674	4.98e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HIENHGCL_00675	1.62e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
HIENHGCL_00676	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00677	6.28e-10	-	-	-	S	-	-	-	CsbD-like
HIENHGCL_00678	3.08e-52	-	-	-	S	-	-	-	Transglycosylase associated protein
HIENHGCL_00679	4.23e-93	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HIENHGCL_00680	1.93e-25	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HIENHGCL_00684	8.04e-188	-	-	-	-	-	-	-	-
HIENHGCL_00685	5.52e-24	adhC	1.1.1.90	-	C	ko:K00055,ko:K06898	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	S-(hydroxymethyl)glutathione dehydrogenase activity
HIENHGCL_00686	4.65e-228	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HIENHGCL_00687	0.0	-	-	-	-	-	-	-	-
HIENHGCL_00688	1.01e-104	-	-	-	-	-	-	-	-
HIENHGCL_00689	1.18e-55	-	-	-	C	-	-	-	FMN_bind
HIENHGCL_00690	2.95e-307	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HIENHGCL_00691	5.27e-57	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HIENHGCL_00692	8.12e-262	pbpX1	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_00693	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIENHGCL_00694	2.42e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HIENHGCL_00695	1.23e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIENHGCL_00696	1.14e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIENHGCL_00697	5.48e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIENHGCL_00698	1.39e-106	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIENHGCL_00699	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIENHGCL_00700	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HIENHGCL_00701	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIENHGCL_00702	1.17e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HIENHGCL_00703	8.42e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIENHGCL_00704	3.02e-294	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIENHGCL_00705	8.19e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIENHGCL_00706	1.45e-195	-	-	-	-	-	-	-	-
HIENHGCL_00707	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIENHGCL_00708	4.08e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIENHGCL_00709	3.78e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HIENHGCL_00710	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HIENHGCL_00711	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HIENHGCL_00712	2.19e-131	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HIENHGCL_00713	1.37e-246	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HIENHGCL_00714	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIENHGCL_00715	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HIENHGCL_00716	4.73e-69	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HIENHGCL_00717	2.75e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HIENHGCL_00718	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HIENHGCL_00719	2.52e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIENHGCL_00720	3.13e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HIENHGCL_00721	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIENHGCL_00722	1.29e-233	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HIENHGCL_00723	0.0	-	-	-	L	-	-	-	Nuclease-related domain
HIENHGCL_00724	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIENHGCL_00725	1.88e-134	-	-	-	S	-	-	-	repeat protein
HIENHGCL_00726	1.58e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HIENHGCL_00727	1.62e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIENHGCL_00728	1.47e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HIENHGCL_00729	1.02e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIENHGCL_00730	4.49e-42	-	-	-	-	-	-	-	-
HIENHGCL_00731	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HIENHGCL_00732	8.09e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HIENHGCL_00733	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIENHGCL_00734	1.18e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HIENHGCL_00735	4.87e-193	ylmH	-	-	S	-	-	-	S4 domain protein
HIENHGCL_00736	1.36e-39	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HIENHGCL_00737	4.09e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIENHGCL_00738	5.9e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIENHGCL_00739	1.02e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIENHGCL_00740	1.71e-182	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIENHGCL_00741	4.93e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIENHGCL_00742	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIENHGCL_00743	8e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIENHGCL_00744	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HIENHGCL_00745	1.32e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HIENHGCL_00746	5.41e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIENHGCL_00747	3.95e-93	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HIENHGCL_00748	4.84e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HIENHGCL_00749	1.45e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HIENHGCL_00750	6.61e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HIENHGCL_00751	1.82e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HIENHGCL_00752	2.03e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HIENHGCL_00753	2.34e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HIENHGCL_00754	1.83e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HIENHGCL_00755	3.52e-261	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HIENHGCL_00756	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIENHGCL_00757	1.56e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HIENHGCL_00758	4.62e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIENHGCL_00759	1.29e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HIENHGCL_00760	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIENHGCL_00761	1.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIENHGCL_00762	9.44e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HIENHGCL_00763	1.18e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HIENHGCL_00764	1.41e-49	-	-	-	-	-	-	-	-
HIENHGCL_00765	6.39e-102	uspA	-	-	T	-	-	-	universal stress protein
HIENHGCL_00766	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HIENHGCL_00767	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HIENHGCL_00768	7.58e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HIENHGCL_00769	2.04e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HIENHGCL_00770	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HIENHGCL_00771	7.03e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HIENHGCL_00772	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIENHGCL_00773	1.22e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIENHGCL_00774	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIENHGCL_00775	6.82e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIENHGCL_00776	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIENHGCL_00777	4.36e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIENHGCL_00778	4.13e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HIENHGCL_00779	1.84e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIENHGCL_00780	4.93e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIENHGCL_00781	2.52e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIENHGCL_00782	1.01e-235	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIENHGCL_00783	4.64e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HIENHGCL_00784	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HIENHGCL_00785	1.58e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIENHGCL_00786	3.5e-75	-	-	-	K	-	-	-	Transcriptional
HIENHGCL_00788	2.58e-49	-	-	-	-	-	-	-	-
HIENHGCL_00789	3.84e-90	-	-	-	-	-	-	-	-
HIENHGCL_00790	6.8e-46	-	-	-	-	-	-	-	-
HIENHGCL_00791	1.18e-47	-	-	-	-	-	-	-	-
HIENHGCL_00792	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
HIENHGCL_00793	2.17e-85	-	-	-	-	-	-	-	-
HIENHGCL_00796	7.36e-251	ampC	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_00797	5.4e-316	-	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_00798	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HIENHGCL_00799	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
HIENHGCL_00800	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIENHGCL_00801	1.53e-159	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HIENHGCL_00802	4.37e-81	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HIENHGCL_00803	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HIENHGCL_00804	1.84e-123	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HIENHGCL_00805	1.68e-81	-	-	-	S	-	-	-	SdpI/YhfL protein family
HIENHGCL_00806	1.86e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HIENHGCL_00807	4.53e-41	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HIENHGCL_00808	3.52e-224	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HIENHGCL_00809	1.05e-170	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HIENHGCL_00811	1.35e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIENHGCL_00812	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HIENHGCL_00813	2.61e-120	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HIENHGCL_00814	1.33e-25	-	-	-	-	-	-	-	-
HIENHGCL_00815	9e-94	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HIENHGCL_00816	1.55e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HIENHGCL_00817	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HIENHGCL_00818	9.02e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HIENHGCL_00819	7.38e-29	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HIENHGCL_00820	1.97e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HIENHGCL_00821	2.34e-119	-	-	-	S	-	-	-	VanZ like family
HIENHGCL_00822	1.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIENHGCL_00824	0.0	-	-	-	E	-	-	-	Amino acid permease
HIENHGCL_00825	6.14e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HIENHGCL_00826	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00827	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_00828	4.66e-196	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HIENHGCL_00829	1.37e-269	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HIENHGCL_00830	2.73e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIENHGCL_00831	7.3e-156	-	-	-	-	-	-	-	-
HIENHGCL_00832	1.45e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIENHGCL_00833	4.85e-191	-	-	-	S	-	-	-	hydrolase
HIENHGCL_00834	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIENHGCL_00835	3.38e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
HIENHGCL_00836	1.06e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIENHGCL_00837	9.5e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_00838	2.65e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_00839	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_00840	2.94e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIENHGCL_00841	7.27e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HIENHGCL_00842	5.26e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HIENHGCL_00843	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HIENHGCL_00844	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HIENHGCL_00845	1.15e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIENHGCL_00846	1.02e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIENHGCL_00847	1.07e-125	-	-	-	-	-	-	-	-
HIENHGCL_00848	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIENHGCL_00849	9.96e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HIENHGCL_00850	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIENHGCL_00851	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HIENHGCL_00853	0.0	ycaM	-	-	E	-	-	-	amino acid
HIENHGCL_00854	0.0	-	-	-	S	-	-	-	SH3-like domain
HIENHGCL_00855	2.16e-129	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIENHGCL_00856	1.17e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HIENHGCL_00857	1.86e-164	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HIENHGCL_00858	2.69e-51	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HIENHGCL_00859	5.03e-81	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HIENHGCL_00860	2.44e-116	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HIENHGCL_00861	3.8e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HIENHGCL_00862	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIENHGCL_00863	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIENHGCL_00864	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIENHGCL_00865	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HIENHGCL_00866	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIENHGCL_00867	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HIENHGCL_00868	5.82e-272	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HIENHGCL_00869	4.02e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIENHGCL_00870	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HIENHGCL_00871	9.38e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIENHGCL_00872	1.71e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HIENHGCL_00873	4.36e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIENHGCL_00874	6.85e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIENHGCL_00875	1.88e-21	-	-	-	-	-	-	-	-
HIENHGCL_00876	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIENHGCL_00877	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIENHGCL_00878	1.75e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIENHGCL_00879	2.26e-137	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HIENHGCL_00880	8.33e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HIENHGCL_00881	2.05e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HIENHGCL_00882	3.37e-271	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HIENHGCL_00883	2.13e-292	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HIENHGCL_00884	6.24e-247	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIENHGCL_00885	1.73e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIENHGCL_00886	1.43e-160	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HIENHGCL_00887	8.02e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HIENHGCL_00888	2.26e-306	ymfH	-	-	S	-	-	-	Peptidase M16
HIENHGCL_00889	4.09e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HIENHGCL_00890	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HIENHGCL_00891	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HIENHGCL_00892	1.75e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIENHGCL_00893	8.9e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HIENHGCL_00894	8.1e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HIENHGCL_00895	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HIENHGCL_00896	1.06e-257	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HIENHGCL_00897	8.93e-153	-	-	-	S	-	-	-	SNARE associated Golgi protein
HIENHGCL_00898	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HIENHGCL_00899	1.81e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HIENHGCL_00900	5.49e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIENHGCL_00901	1.15e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HIENHGCL_00902	1.46e-145	-	-	-	S	-	-	-	CYTH
HIENHGCL_00903	7.54e-149	yjbH	-	-	Q	-	-	-	Thioredoxin
HIENHGCL_00904	2.56e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HIENHGCL_00905	2.91e-175	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIENHGCL_00906	1.08e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIENHGCL_00907	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIENHGCL_00908	9.05e-55	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HIENHGCL_00909	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HIENHGCL_00910	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HIENHGCL_00911	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIENHGCL_00912	1.48e-127	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HIENHGCL_00913	1.25e-62	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HIENHGCL_00914	1.02e-93	-	-	-	-	-	-	-	-
HIENHGCL_00915	7.42e-112	-	-	-	-	-	-	-	-
HIENHGCL_00916	4.13e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HIENHGCL_00917	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIENHGCL_00918	2.13e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HIENHGCL_00919	2.95e-61	-	-	-	-	-	-	-	-
HIENHGCL_00920	3.82e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HIENHGCL_00921	1.39e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HIENHGCL_00922	3.81e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HIENHGCL_00923	6.78e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HIENHGCL_00924	1.14e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HIENHGCL_00925	7.02e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HIENHGCL_00926	8.53e-104	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HIENHGCL_00927	4.67e-116	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HIENHGCL_00928	4.97e-81	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HIENHGCL_00929	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HIENHGCL_00930	2.47e-221	-	-	-	-	-	-	-	-
HIENHGCL_00931	3.71e-300	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_00932	2.53e-283	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIENHGCL_00933	7.59e-269	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HIENHGCL_00934	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HIENHGCL_00935	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIENHGCL_00936	4.62e-181	-	-	-	-	-	-	-	-
HIENHGCL_00937	2.12e-176	-	-	-	-	-	-	-	-
HIENHGCL_00938	1.84e-170	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIENHGCL_00939	8.51e-143	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIENHGCL_00940	1.96e-132	-	-	-	G	-	-	-	Aldose 1-epimerase
HIENHGCL_00941	1.34e-259	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIENHGCL_00942	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIENHGCL_00943	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HIENHGCL_00944	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
HIENHGCL_00945	6.28e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIENHGCL_00946	1.02e-74	-	-	-	-	-	-	-	-
HIENHGCL_00948	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HIENHGCL_00949	1.16e-162	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIENHGCL_00950	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIENHGCL_00951	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIENHGCL_00952	8.86e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIENHGCL_00953	5.46e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIENHGCL_00954	1.92e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIENHGCL_00955	1.9e-256	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_00956	1.87e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_00957	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HIENHGCL_00958	1.5e-96	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HIENHGCL_00959	6.92e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIENHGCL_00960	1.09e-148	-	-	-	-	-	-	-	-
HIENHGCL_00962	1.21e-146	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HIENHGCL_00963	2.35e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIENHGCL_00964	2.69e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HIENHGCL_00965	1.25e-142	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HIENHGCL_00966	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HIENHGCL_00967	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIENHGCL_00968	2.33e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HIENHGCL_00969	1.63e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIENHGCL_00970	4.9e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIENHGCL_00971	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HIENHGCL_00972	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HIENHGCL_00973	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIENHGCL_00974	1.4e-116	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_00975	4.55e-117	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_00976	1.48e-114	-	-	-	-	-	-	-	-
HIENHGCL_00977	0.0	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_00978	2.68e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIENHGCL_00979	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_00980	3.82e-167	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HIENHGCL_00981	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_00982	4.58e-216	-	-	-	GK	-	-	-	ROK family
HIENHGCL_00983	4.88e-59	-	-	-	-	-	-	-	-
HIENHGCL_00984	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIENHGCL_00985	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HIENHGCL_00986	1.11e-96	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIENHGCL_00987	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIENHGCL_00988	6.32e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIENHGCL_00989	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIENHGCL_00990	7.87e-207	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
HIENHGCL_00991	1.87e-137	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HIENHGCL_00992	2.84e-284	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HIENHGCL_00993	5.8e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIENHGCL_00994	1.04e-173	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HIENHGCL_00995	3.77e-220	-	-	-	K	-	-	-	Helix-turn-helix
HIENHGCL_00996	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HIENHGCL_00997	7.77e-199	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_00998	3.12e-191	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HIENHGCL_00999	2.08e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIENHGCL_01000	1.16e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HIENHGCL_01001	7.88e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIENHGCL_01002	9.09e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HIENHGCL_01003	2.07e-117	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
HIENHGCL_01004	2.89e-44	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
HIENHGCL_01005	5.49e-42	-	-	-	-	-	-	-	-
HIENHGCL_01006	3.18e-106	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIENHGCL_01007	6.74e-39	-	-	-	K	ko:K12410	-	ko00000,ko01000	NAD+ binding
HIENHGCL_01008	4.62e-13	-	-	-	P	-	-	-	Voltage gated chloride channel
HIENHGCL_01009	7.47e-126	-	-	-	-	-	-	-	-
HIENHGCL_01010	8.2e-68	-	-	-	-	-	-	-	-
HIENHGCL_01011	4.88e-59	-	-	-	-	-	-	-	-
HIENHGCL_01012	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIENHGCL_01013	0.0	-	-	-	E	-	-	-	amino acid
HIENHGCL_01014	9.8e-204	supH	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HIENHGCL_01015	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HIENHGCL_01016	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HIENHGCL_01017	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIENHGCL_01018	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIENHGCL_01019	3.27e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIENHGCL_01020	2.68e-275	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIENHGCL_01021	1.44e-165	-	-	-	S	-	-	-	(CBS) domain
HIENHGCL_01022	1.98e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HIENHGCL_01023	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIENHGCL_01024	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIENHGCL_01025	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIENHGCL_01026	1.79e-46	yabO	-	-	J	-	-	-	S4 domain protein
HIENHGCL_01027	1.03e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HIENHGCL_01028	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HIENHGCL_01029	5.11e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIENHGCL_01030	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIENHGCL_01031	6.77e-215	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIENHGCL_01032	3.5e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIENHGCL_01033	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HIENHGCL_01037	1.16e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HIENHGCL_01038	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIENHGCL_01039	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIENHGCL_01040	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIENHGCL_01041	6.6e-159	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HIENHGCL_01042	2.09e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIENHGCL_01043	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIENHGCL_01044	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIENHGCL_01045	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HIENHGCL_01046	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIENHGCL_01047	1.91e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HIENHGCL_01048	7.21e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIENHGCL_01049	9.85e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIENHGCL_01050	1.34e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIENHGCL_01051	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIENHGCL_01052	7.15e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIENHGCL_01053	9.64e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIENHGCL_01054	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HIENHGCL_01055	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIENHGCL_01056	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIENHGCL_01057	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIENHGCL_01058	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIENHGCL_01059	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIENHGCL_01060	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIENHGCL_01061	2.5e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIENHGCL_01062	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIENHGCL_01063	5.3e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIENHGCL_01064	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HIENHGCL_01065	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HIENHGCL_01066	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIENHGCL_01067	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIENHGCL_01068	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIENHGCL_01069	4.63e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HIENHGCL_01070	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIENHGCL_01071	3.95e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIENHGCL_01072	2.55e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIENHGCL_01073	1.57e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HIENHGCL_01074	4.16e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIENHGCL_01075	4.04e-206	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIENHGCL_01076	1.74e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIENHGCL_01077	4.17e-192	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIENHGCL_01078	1.6e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIENHGCL_01079	8.28e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HIENHGCL_01080	5.27e-16	-	-	-	-	-	-	-	-
HIENHGCL_01081	3.63e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HIENHGCL_01082	4.67e-154	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIENHGCL_01083	8.09e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HIENHGCL_01084	6.91e-164	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HIENHGCL_01085	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HIENHGCL_01086	1.14e-27	-	-	-	-	-	-	-	-
HIENHGCL_01087	1.27e-104	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIENHGCL_01088	9.84e-236	-	-	-	S	-	-	-	AAA domain
HIENHGCL_01089	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIENHGCL_01090	9.95e-70	-	-	-	-	-	-	-	-
HIENHGCL_01091	1.82e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HIENHGCL_01092	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIENHGCL_01093	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIENHGCL_01094	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIENHGCL_01095	6.01e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIENHGCL_01096	8.7e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIENHGCL_01097	2.91e-121	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HIENHGCL_01098	2.41e-45	-	-	-	-	-	-	-	-
HIENHGCL_01099	6.48e-148	-	-	-	-	-	-	-	-
HIENHGCL_01100	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HIENHGCL_01101	1.22e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIENHGCL_01102	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIENHGCL_01103	1.72e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIENHGCL_01104	3.66e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HIENHGCL_01105	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIENHGCL_01106	1.5e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIENHGCL_01107	2.83e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HIENHGCL_01108	1.8e-223	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HIENHGCL_01109	4.47e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HIENHGCL_01110	4.47e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIENHGCL_01111	5.67e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIENHGCL_01112	1.74e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HIENHGCL_01113	3.62e-268	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HIENHGCL_01114	1.86e-38	-	-	-	-	-	-	-	-
HIENHGCL_01115	2.15e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIENHGCL_01116	9.31e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIENHGCL_01117	3.83e-167	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HIENHGCL_01118	1.25e-147	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HIENHGCL_01119	4.9e-33	-	-	-	-	-	-	-	-
HIENHGCL_01120	1.31e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIENHGCL_01121	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIENHGCL_01122	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_01123	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_01124	5.84e-202	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01125	1.49e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_01126	8.73e-234	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_01127	1.43e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_01128	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIENHGCL_01129	3.16e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIENHGCL_01130	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIENHGCL_01131	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HIENHGCL_01132	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HIENHGCL_01133	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HIENHGCL_01134	1.5e-68	-	-	-	-	-	-	-	-
HIENHGCL_01135	1.42e-104	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HIENHGCL_01136	5.27e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HIENHGCL_01137	1.37e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIENHGCL_01138	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HIENHGCL_01139	9.79e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HIENHGCL_01140	4.61e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIENHGCL_01141	1.08e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIENHGCL_01142	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIENHGCL_01143	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIENHGCL_01144	2.53e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HIENHGCL_01145	2.88e-105	-	-	-	S	-	-	-	ASCH
HIENHGCL_01146	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HIENHGCL_01147	1.52e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HIENHGCL_01148	1.84e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HIENHGCL_01149	3.76e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIENHGCL_01150	5.86e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIENHGCL_01151	5.91e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIENHGCL_01152	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIENHGCL_01153	2.57e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HIENHGCL_01154	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIENHGCL_01155	3.69e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HIENHGCL_01156	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HIENHGCL_01157	4.8e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HIENHGCL_01158	3.54e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIENHGCL_01159	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HIENHGCL_01160	3.98e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HIENHGCL_01161	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HIENHGCL_01162	4.41e-137	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HIENHGCL_01163	9.64e-141	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HIENHGCL_01164	7.45e-09	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_01165	9.58e-80	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_01166	7.38e-127	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_01167	3.88e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
HIENHGCL_01168	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIENHGCL_01169	3.04e-198	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HIENHGCL_01170	1.52e-243	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIENHGCL_01172	4.22e-211	-	-	-	S	-	-	-	Membrane
HIENHGCL_01173	1.75e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
HIENHGCL_01174	4.8e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HIENHGCL_01175	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_01176	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_01177	1.84e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HIENHGCL_01178	0.0	-	-	-	-	-	-	-	-
HIENHGCL_01179	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HIENHGCL_01180	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HIENHGCL_01181	0.0	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_01182	7.89e-213	-	2.7.1.85	-	GK	ko:K18673	-	ko00000,ko01000	ROK family
HIENHGCL_01183	3.58e-262	xylR	-	-	GK	-	-	-	ROK family
HIENHGCL_01184	4.89e-301	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_01185	9.35e-128	-	-	-	S	-	-	-	Bacterial PH domain
HIENHGCL_01186	3.5e-22	-	-	-	-	-	-	-	-
HIENHGCL_01187	1.02e-85	-	-	-	K	-	-	-	sequence-specific DNA binding
HIENHGCL_01188	2.45e-63	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
HIENHGCL_01189	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIENHGCL_01190	1.67e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HIENHGCL_01191	2.43e-62	-	-	-	-	-	-	-	-
HIENHGCL_01192	1.74e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HIENHGCL_01193	0.0	-	-	-	-	-	-	-	-
HIENHGCL_01194	2.73e-07	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HIENHGCL_01195	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HIENHGCL_01196	2.85e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HIENHGCL_01197	1.47e-191	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIENHGCL_01198	8.15e-69	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIENHGCL_01199	3.43e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HIENHGCL_01200	1.75e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIENHGCL_01201	1.71e-33	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIENHGCL_01202	2.33e-164	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIENHGCL_01203	7.44e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIENHGCL_01204	9.13e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIENHGCL_01205	3.3e-152	-	-	-	GM	-	-	-	NmrA-like family
HIENHGCL_01206	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIENHGCL_01207	9.28e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HIENHGCL_01208	1.86e-141	-	-	-	O	-	-	-	Matrixin
HIENHGCL_01209	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIENHGCL_01210	3.89e-122	-	-	-	K	-	-	-	acetyltransferase
HIENHGCL_01211	1.65e-66	-	-	-	-	-	-	-	-
HIENHGCL_01212	2.34e-204	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HIENHGCL_01213	2.87e-62	-	-	-	-	-	-	-	-
HIENHGCL_01214	7.22e-161	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HIENHGCL_01215	1.15e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIENHGCL_01216	2.66e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HIENHGCL_01217	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_01219	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HIENHGCL_01220	7.81e-82	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HIENHGCL_01221	3.88e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HIENHGCL_01222	1.77e-150	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HIENHGCL_01223	2.97e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIENHGCL_01224	8.85e-85	-	-	-	S	-	-	-	ASCH domain
HIENHGCL_01225	6.71e-153	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HIENHGCL_01227	5.31e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HIENHGCL_01228	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HIENHGCL_01231	2.26e-267	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HIENHGCL_01232	1.63e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HIENHGCL_01233	8.74e-192	-	-	-	T	-	-	-	EAL domain
HIENHGCL_01234	3.81e-58	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HIENHGCL_01235	4.05e-233	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HIENHGCL_01236	3.07e-119	-	-	-	-	-	-	-	-
HIENHGCL_01237	9.37e-227	-	-	-	C	-	-	-	Oxidoreductase
HIENHGCL_01239	4.69e-271	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
HIENHGCL_01240	4.27e-37	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
HIENHGCL_01241	4.83e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
HIENHGCL_01242	2.86e-19	-	-	-	-	-	-	-	-
HIENHGCL_01243	0.0	potE	-	-	E	-	-	-	Amino Acid
HIENHGCL_01244	2.05e-163	-	-	-	S	-	-	-	Alpha beta hydrolase
HIENHGCL_01246	1.31e-165	-	-	-	-	-	-	-	-
HIENHGCL_01247	5.44e-163	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
HIENHGCL_01248	8.84e-93	-	-	-	O	-	-	-	OsmC-like protein
HIENHGCL_01249	3.65e-272	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIENHGCL_01250	5.46e-297	sptS	-	-	T	-	-	-	Histidine kinase
HIENHGCL_01251	1.28e-152	dltr	-	-	K	-	-	-	response regulator
HIENHGCL_01252	4.2e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HIENHGCL_01253	7.55e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HIENHGCL_01254	1.31e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HIENHGCL_01255	8.2e-81	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HIENHGCL_01256	1.63e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIENHGCL_01257	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HIENHGCL_01258	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HIENHGCL_01259	3.33e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_01260	7.19e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01261	1.98e-200	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01262	6.26e-309	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIENHGCL_01263	2.43e-204	lacR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIENHGCL_01264	2.78e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HIENHGCL_01265	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HIENHGCL_01266	4.02e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HIENHGCL_01267	9.46e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HIENHGCL_01268	1.53e-61	-	-	-	-	-	-	-	-
HIENHGCL_01270	3.46e-53	-	-	-	C	-	-	-	FMN binding
HIENHGCL_01271	1.42e-215	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_01272	5.56e-246	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HIENHGCL_01273	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HIENHGCL_01274	1.45e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIENHGCL_01275	9.91e-241	-	-	-	M	-	-	-	domain protein
HIENHGCL_01276	1.51e-145	-	-	-	-	-	-	-	-
HIENHGCL_01277	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HIENHGCL_01278	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HIENHGCL_01281	6.86e-311	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_01282	2.35e-269	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HIENHGCL_01283	9.79e-168	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIENHGCL_01284	3.27e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
HIENHGCL_01285	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HIENHGCL_01286	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HIENHGCL_01287	4.33e-154	-	-	-	C	-	-	-	nitroreductase
HIENHGCL_01288	1.51e-53	-	-	-	-	-	-	-	-
HIENHGCL_01289	5.61e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIENHGCL_01290	2.25e-105	-	-	-	-	-	-	-	-
HIENHGCL_01291	3.69e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HIENHGCL_01292	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HIENHGCL_01293	1.35e-196	-	-	-	S	-	-	-	hydrolase
HIENHGCL_01294	5.93e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIENHGCL_01295	8.04e-187	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HIENHGCL_01296	7.37e-293	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HIENHGCL_01297	2.25e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
HIENHGCL_01298	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HIENHGCL_01299	3.4e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HIENHGCL_01300	7.73e-79	-	-	-	S	-	-	-	Enterocin A Immunity
HIENHGCL_01301	8.25e-221	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HIENHGCL_01302	3.85e-143	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HIENHGCL_01303	1.21e-93	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HIENHGCL_01304	2.07e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HIENHGCL_01305	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIENHGCL_01306	5.7e-146	-	-	-	-	-	-	-	-
HIENHGCL_01307	1.81e-28	-	-	-	-	-	-	-	-
HIENHGCL_01308	1.98e-175	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HIENHGCL_01309	3.51e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HIENHGCL_01310	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HIENHGCL_01311	1.56e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIENHGCL_01312	9.2e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIENHGCL_01313	5.34e-211	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HIENHGCL_01314	5.02e-313	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIENHGCL_01315	2.75e-95	-	-	-	-	-	-	-	-
HIENHGCL_01316	3.66e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HIENHGCL_01317	8.28e-143	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_01318	1.43e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_01319	4.3e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_01320	2.39e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01321	1.92e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HIENHGCL_01322	8.88e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HIENHGCL_01323	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HIENHGCL_01324	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01325	6.57e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HIENHGCL_01326	2.22e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIENHGCL_01327	1.4e-188	-	-	-	-	-	-	-	-
HIENHGCL_01328	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HIENHGCL_01329	7.56e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HIENHGCL_01330	1.11e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HIENHGCL_01331	3.81e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HIENHGCL_01332	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_01333	2.03e-67	-	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HIENHGCL_01334	3.27e-110	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HIENHGCL_01335	1.39e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIENHGCL_01336	5.36e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HIENHGCL_01337	5.81e-165	XK27_08575	-	-	V	ko:K06148	-	ko00000,ko02000	cysteine transport
HIENHGCL_01338	5.13e-141	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIENHGCL_01339	1.36e-205	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HIENHGCL_01340	3.79e-101	-	-	-	K	-	-	-	acetyltransferase
HIENHGCL_01341	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HIENHGCL_01342	1.25e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIENHGCL_01343	1.88e-174	-	-	-	S	-	-	-	CAAX protease self-immunity
HIENHGCL_01344	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_01349	3.49e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIENHGCL_01350	9.05e-231	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HIENHGCL_01351	3.28e-122	-	-	-	L	-	-	-	Resolvase, N terminal domain
HIENHGCL_01352	2.98e-246	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HIENHGCL_01353	2.43e-76	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HIENHGCL_01354	3.15e-62	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HIENHGCL_01355	5.16e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HIENHGCL_01356	9.1e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HIENHGCL_01357	1.05e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HIENHGCL_01358	5.51e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HIENHGCL_01359	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HIENHGCL_01360	1.48e-82	-	-	-	-	-	-	-	-
HIENHGCL_01361	4.2e-30	-	-	-	-	-	-	-	-
HIENHGCL_01362	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIENHGCL_01363	1.28e-310	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HIENHGCL_01364	4.94e-75	-	-	-	-	-	-	-	-
HIENHGCL_01365	5.45e-93	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HIENHGCL_01366	2.37e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HIENHGCL_01367	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIENHGCL_01368	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIENHGCL_01369	4.46e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIENHGCL_01370	7.29e-267	camS	-	-	S	-	-	-	sex pheromone
HIENHGCL_01371	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIENHGCL_01372	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HIENHGCL_01373	1.02e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HIENHGCL_01375	6.32e-83	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HIENHGCL_01376	8.44e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HIENHGCL_01377	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIENHGCL_01378	3.89e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIENHGCL_01379	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIENHGCL_01380	5.7e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIENHGCL_01381	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIENHGCL_01382	1.85e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
HIENHGCL_01383	1.39e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIENHGCL_01384	2.13e-92	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HIENHGCL_01385	1.33e-160	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HIENHGCL_01386	5.81e-272	-	-	-	-	-	-	-	-
HIENHGCL_01389	0.0	slpX	-	-	S	-	-	-	SLAP domain
HIENHGCL_01390	3.91e-226	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HIENHGCL_01392	3.18e-92	-	-	-	EGP	-	-	-	Major Facilitator
HIENHGCL_01393	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HIENHGCL_01394	2.07e-234	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_01395	4.18e-292	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HIENHGCL_01396	2.93e-199	msmG	-	-	G	ko:K02026,ko:K10122	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01397	1.78e-209	-	-	-	P	ko:K10121	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HIENHGCL_01398	0.0	-	-	-	G	ko:K02027,ko:K10120	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIENHGCL_01399	7.11e-236	lacI	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIENHGCL_01400	9.11e-69	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HIENHGCL_01401	9.82e-156	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HIENHGCL_01402	2.57e-139	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HIENHGCL_01403	1e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIENHGCL_01404	3.81e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
HIENHGCL_01405	2.62e-111	-	-	-	M	-	-	-	LysM domain protein
HIENHGCL_01406	4.35e-207	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HIENHGCL_01407	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_01408	2.6e-19	-	-	-	-	-	-	-	-
HIENHGCL_01409	1.48e-219	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HIENHGCL_01410	3.99e-88	-	-	-	-	-	-	-	-
HIENHGCL_01411	3.99e-45	-	-	-	-	-	-	-	-
HIENHGCL_01412	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HIENHGCL_01413	1.14e-295	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIENHGCL_01414	6.89e-06	-	-	-	-	-	-	-	-
HIENHGCL_01415	3.69e-244	-	-	-	EP	-	-	-	Plasmid replication protein
HIENHGCL_01417	2.66e-270	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIENHGCL_01418	8.66e-76	-	-	-	-	-	-	-	-
HIENHGCL_01420	8.37e-161	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HIENHGCL_01421	1.46e-191	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HIENHGCL_01422	4.51e-59	-	-	-	S	-	-	-	AAA ATPase domain
HIENHGCL_01423	0.0	-	-	-	S	-	-	-	AAA ATPase domain
HIENHGCL_01424	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
HIENHGCL_01426	8.42e-187	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HIENHGCL_01427	1.14e-294	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HIENHGCL_01428	4.47e-81	-	-	-	-	-	-	-	-
HIENHGCL_01429	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HIENHGCL_01430	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HIENHGCL_01431	0.0	-	-	-	S	-	-	-	TerB-C domain
HIENHGCL_01432	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HIENHGCL_01433	8.15e-94	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HIENHGCL_01434	1.63e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HIENHGCL_01435	1.47e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIENHGCL_01436	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIENHGCL_01437	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HIENHGCL_01438	2.27e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HIENHGCL_01439	3.62e-89	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HIENHGCL_01440	7.93e-206	-	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_01441	2.86e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HIENHGCL_01442	1.18e-225	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HIENHGCL_01443	1.67e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HIENHGCL_01444	1.36e-241	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HIENHGCL_01446	2.76e-48	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIENHGCL_01447	2.52e-84	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HIENHGCL_01448	1.63e-175	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HIENHGCL_01449	1.34e-298	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HIENHGCL_01450	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HIENHGCL_01451	1.23e-255	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HIENHGCL_01452	1.86e-287	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HIENHGCL_01453	7.58e-244	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
HIENHGCL_01454	2.89e-150	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HIENHGCL_01455	1.07e-113	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HIENHGCL_01456	1.49e-74	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HIENHGCL_01457	4.02e-192	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HIENHGCL_01458	1.77e-159	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HIENHGCL_01459	7.21e-190	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HIENHGCL_01460	4.87e-165	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HIENHGCL_01461	1.01e-193	epsB	-	-	M	-	-	-	biosynthesis protein
HIENHGCL_01462	5.44e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIENHGCL_01463	1.42e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIENHGCL_01464	5.52e-241	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HIENHGCL_01465	0.0	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
HIENHGCL_01466	1.4e-204	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIENHGCL_01467	2.99e-176	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HIENHGCL_01468	7.09e-125	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIENHGCL_01469	6.94e-110	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HIENHGCL_01470	2.96e-56	-	-	-	-	-	-	-	-
HIENHGCL_01471	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HIENHGCL_01472	4.7e-143	-	-	-	-	-	-	-	-
HIENHGCL_01473	7.02e-103	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HIENHGCL_01474	2.71e-233	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIENHGCL_01475	1.36e-105	-	-	-	-	-	-	-	-
HIENHGCL_01476	3.7e-175	-	-	-	S	-	-	-	Peptidase_C39 like family
HIENHGCL_01477	1.47e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HIENHGCL_01478	1.08e-62	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HIENHGCL_01479	1.64e-47	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HIENHGCL_01480	4.44e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HIENHGCL_01481	3.12e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
HIENHGCL_01482	0.0	-	-	-	S	-	-	-	ABC transporter
HIENHGCL_01483	3.08e-81	-	-	-	-	-	-	-	-
HIENHGCL_01484	2.7e-59	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIENHGCL_01485	5.01e-293	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIENHGCL_01486	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HIENHGCL_01487	9.86e-59	-	-	-	P	ko:K03449	-	ko00000,ko02000	transmembrane transport
HIENHGCL_01488	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HIENHGCL_01489	1.04e-82	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HIENHGCL_01490	6.99e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HIENHGCL_01491	6.65e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HIENHGCL_01492	1.79e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HIENHGCL_01493	7.83e-60	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HIENHGCL_01494	3e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIENHGCL_01495	4.7e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HIENHGCL_01496	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HIENHGCL_01497	1.31e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HIENHGCL_01498	1.49e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HIENHGCL_01499	6.57e-252	-	-	-	S	-	-	-	Fic/DOC family
HIENHGCL_01500	1.22e-274	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HIENHGCL_01501	1.6e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01502	2.89e-12	-	-	-	-	-	-	-	-
HIENHGCL_01503	4.14e-89	-	-	-	-	-	-	-	-
HIENHGCL_01504	6.68e-35	-	-	-	-	-	-	-	-
HIENHGCL_01505	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HIENHGCL_01506	9.7e-116	-	-	-	-	-	-	-	-
HIENHGCL_01507	2.26e-29	-	-	-	-	-	-	-	-
HIENHGCL_01512	1.21e-275	blpT	-	-	-	-	-	-	-
HIENHGCL_01513	3.21e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HIENHGCL_01514	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HIENHGCL_01517	7.63e-190	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HIENHGCL_01518	4.67e-297	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HIENHGCL_01519	2e-06	-	-	-	-	-	-	-	-
HIENHGCL_01522	2.6e-141	-	-	-	-	-	-	-	-
HIENHGCL_01524	2.71e-136	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIENHGCL_01525	5.21e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIENHGCL_01526	2.62e-50	-	-	-	S	-	-	-	Enterocin A Immunity
HIENHGCL_01527	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HIENHGCL_01528	9.17e-37	-	-	-	-	-	-	-	-
HIENHGCL_01529	1.47e-45	-	-	-	-	-	-	-	-
HIENHGCL_01530	1.4e-69	-	-	-	S	-	-	-	Enterocin A Immunity
HIENHGCL_01531	5.63e-64	-	-	-	S	-	-	-	Enterocin A Immunity
HIENHGCL_01532	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HIENHGCL_01533	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIENHGCL_01534	9.58e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HIENHGCL_01535	1.44e-157	vanR	-	-	K	-	-	-	response regulator
HIENHGCL_01536	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HIENHGCL_01537	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01538	1.55e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HIENHGCL_01539	1.39e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIENHGCL_01540	2.22e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HIENHGCL_01541	2.05e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HIENHGCL_01542	4.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HIENHGCL_01543	2.79e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HIENHGCL_01544	3.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HIENHGCL_01545	8.5e-105	cvpA	-	-	S	-	-	-	Colicin V production protein
HIENHGCL_01546	6.64e-233	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIENHGCL_01547	9.1e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIENHGCL_01548	6.34e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HIENHGCL_01549	4.14e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HIENHGCL_01550	2.15e-144	-	-	-	K	-	-	-	WHG domain
HIENHGCL_01551	1.59e-49	-	-	-	-	-	-	-	-
HIENHGCL_01552	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIENHGCL_01553	3.26e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01554	1.43e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIENHGCL_01555	1.45e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIENHGCL_01556	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
HIENHGCL_01557	1.19e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HIENHGCL_01558	4.33e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HIENHGCL_01559	3.44e-153	-	-	-	-	-	-	-	-
HIENHGCL_01560	3.08e-204	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HIENHGCL_01561	1.71e-282	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HIENHGCL_01562	2.13e-36	-	-	-	-	-	-	-	-
HIENHGCL_01563	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HIENHGCL_01564	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HIENHGCL_01565	7.67e-80	lysM	-	-	M	-	-	-	LysM domain
HIENHGCL_01566	9.68e-226	-	-	-	-	-	-	-	-
HIENHGCL_01567	3e-133	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIENHGCL_01568	8.59e-148	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HIENHGCL_01570	1.97e-280	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HIENHGCL_01571	1.53e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HIENHGCL_01572	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HIENHGCL_01575	2.49e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_01576	2.56e-110	-	-	-	-	-	-	-	-
HIENHGCL_01577	8.05e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIENHGCL_01578	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01579	1.35e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIENHGCL_01580	6e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIENHGCL_01581	1.31e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HIENHGCL_01588	7.66e-181	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HIENHGCL_01589	1.16e-175	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HIENHGCL_01590	6.91e-235	-	-	-	-	-	-	-	-
HIENHGCL_01591	4.05e-119	-	-	-	-	-	-	-	-
HIENHGCL_01592	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HIENHGCL_01594	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
HIENHGCL_01595	4.37e-205	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HIENHGCL_01596	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_01597	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIENHGCL_01598	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIENHGCL_01599	1.24e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIENHGCL_01600	2.88e-107	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HIENHGCL_01601	1.61e-134	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HIENHGCL_01602	1.96e-192	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HIENHGCL_01603	3.86e-239	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIENHGCL_01604	7.86e-240	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIENHGCL_01605	1.71e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HIENHGCL_01606	1.56e-256	-	-	-	S	-	-	-	Membrane
HIENHGCL_01607	5.59e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HIENHGCL_01608	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HIENHGCL_01609	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
HIENHGCL_01612	3.39e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HIENHGCL_01613	1.6e-119	-	-	-	-	-	-	-	-
HIENHGCL_01614	8.44e-201	-	-	-	-	-	-	-	-
HIENHGCL_01615	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HIENHGCL_01616	7.07e-178	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HIENHGCL_01617	1.35e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HIENHGCL_01618	1.25e-22	-	-	-	-	-	-	-	-
HIENHGCL_01619	3.45e-64	-	-	-	-	-	-	-	-
HIENHGCL_01620	3.66e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HIENHGCL_01621	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIENHGCL_01622	2.15e-50	-	-	-	-	-	-	-	-
HIENHGCL_01623	8.94e-26	-	-	-	-	-	-	-	-
HIENHGCL_01624	7.62e-308	-	-	-	S	-	-	-	response to antibiotic
HIENHGCL_01625	3.02e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01626	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIENHGCL_01627	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HIENHGCL_01628	1.69e-160	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HIENHGCL_01629	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HIENHGCL_01630	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HIENHGCL_01631	1.29e-140	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HIENHGCL_01632	2.71e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HIENHGCL_01633	1.25e-106	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HIENHGCL_01634	1.68e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HIENHGCL_01635	3.51e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HIENHGCL_01636	8.57e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIENHGCL_01637	9.2e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIENHGCL_01638	2.28e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HIENHGCL_01639	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIENHGCL_01640	3.59e-123	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HIENHGCL_01641	4.9e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
HIENHGCL_01642	1.34e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIENHGCL_01643	2.36e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIENHGCL_01644	1.59e-299	-	-	-	T	-	-	-	GHKL domain
HIENHGCL_01645	2.91e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HIENHGCL_01646	5.44e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HIENHGCL_01647	1.85e-246	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIENHGCL_01648	3.75e-111	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIENHGCL_01649	9.1e-184	-	-	-	S	-	-	-	PAS domain
HIENHGCL_01650	7.95e-64	-	-	-	-	-	-	-	-
HIENHGCL_01651	0.0	-	-	-	-	-	-	-	-
HIENHGCL_01652	3.05e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HIENHGCL_01653	0.0	-	-	-	M	-	-	-	domain protein
HIENHGCL_01654	9.54e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HIENHGCL_01655	7.21e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HIENHGCL_01656	4.72e-200	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIENHGCL_01657	4e-234	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HIENHGCL_01658	4.53e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HIENHGCL_01659	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIENHGCL_01660	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIENHGCL_01661	1.24e-197	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HIENHGCL_01662	1.68e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIENHGCL_01663	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HIENHGCL_01664	2.47e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIENHGCL_01665	7.19e-202	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HIENHGCL_01666	2.62e-198	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HIENHGCL_01667	1.8e-124	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIENHGCL_01668	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HIENHGCL_01669	6.9e-220	-	-	-	-	-	-	-	-
HIENHGCL_01670	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HIENHGCL_01671	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HIENHGCL_01672	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HIENHGCL_01673	3.62e-121	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HIENHGCL_01674	4.92e-207	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HIENHGCL_01675	1.84e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIENHGCL_01676	1.47e-144	-	-	-	S	-	-	-	SNARE associated Golgi protein
HIENHGCL_01677	1.28e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIENHGCL_01678	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIENHGCL_01679	3.53e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIENHGCL_01680	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HIENHGCL_01681	6.91e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HIENHGCL_01682	1.63e-152	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HIENHGCL_01683	1.19e-175	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIENHGCL_01684	1.25e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
HIENHGCL_01685	4.74e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIENHGCL_01686	9.19e-266	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIENHGCL_01687	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HIENHGCL_01688	9.41e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HIENHGCL_01689	1.21e-236	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HIENHGCL_01690	4.51e-134	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HIENHGCL_01691	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01692	3.39e-253	-	-	-	S	-	-	-	DUF218 domain
HIENHGCL_01693	2.41e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIENHGCL_01694	1.4e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_01695	5.7e-125	-	-	-	M	-	-	-	CHAP domain
HIENHGCL_01696	1.57e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIENHGCL_01697	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HIENHGCL_01698	2.82e-105	-	-	-	S	-	-	-	Putative adhesin
HIENHGCL_01699	4.69e-262	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HIENHGCL_01700	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HIENHGCL_01701	1.97e-107	ykuL	-	-	S	-	-	-	(CBS) domain
HIENHGCL_01702	8.03e-278	-	-	-	S	-	-	-	Membrane
HIENHGCL_01703	2.18e-53	-	-	-	-	-	-	-	-
HIENHGCL_01704	2.17e-25	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HIENHGCL_01705	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIENHGCL_01706	3.35e-310	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HIENHGCL_01707	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIENHGCL_01708	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIENHGCL_01709	3.4e-228	pbpX2	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_01710	2.86e-81	-	-	-	-	-	-	-	-
HIENHGCL_01711	9.09e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HIENHGCL_01712	9.26e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIENHGCL_01713	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIENHGCL_01714	5.63e-49	-	-	-	-	-	-	-	-
HIENHGCL_01715	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIENHGCL_01716	8.01e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01717	1e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIENHGCL_01718	4.24e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HIENHGCL_01719	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HIENHGCL_01720	1.07e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HIENHGCL_01721	0.0	-	-	-	L	-	-	-	Transposase
HIENHGCL_01722	8.71e-157	-	-	-	-	-	-	-	-
HIENHGCL_01723	4.27e-293	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HIENHGCL_01724	1.84e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIENHGCL_01725	1.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HIENHGCL_01726	1e-305	-	-	-	E	-	-	-	amino acid
HIENHGCL_01727	1.27e-70	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HIENHGCL_01728	1.75e-10	-	-	-	-	-	-	-	-
HIENHGCL_01729	6.09e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
HIENHGCL_01730	1.23e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIENHGCL_01731	6.65e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HIENHGCL_01732	4.88e-225	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HIENHGCL_01733	1.69e-259	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HIENHGCL_01736	2.84e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIENHGCL_01737	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIENHGCL_01738	1.14e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIENHGCL_01739	6.33e-74	-	-	-	-	-	-	-	-
HIENHGCL_01740	7.08e-137	-	-	-	-	-	-	-	-
HIENHGCL_01741	1.41e-209	yicL	-	-	EG	-	-	-	EamA-like transporter family
HIENHGCL_01742	1.03e-211	-	-	-	EG	-	-	-	EamA-like transporter family
HIENHGCL_01743	8.16e-212	-	-	-	EG	-	-	-	EamA-like transporter family
HIENHGCL_01744	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
HIENHGCL_01745	1.91e-171	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HIENHGCL_01746	9.67e-220	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HIENHGCL_01747	1.23e-83	-	-	-	S	-	-	-	Protein conserved in bacteria
HIENHGCL_01748	6.65e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HIENHGCL_01749	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIENHGCL_01750	1.06e-20	-	-	-	-	-	-	-	-
HIENHGCL_01751	4.8e-99	-	-	-	-	-	-	-	-
HIENHGCL_01752	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HIENHGCL_01753	7.79e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIENHGCL_01754	7.43e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIENHGCL_01755	1.82e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIENHGCL_01756	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HIENHGCL_01757	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HIENHGCL_01758	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HIENHGCL_01759	1.23e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HIENHGCL_01760	9.9e-240	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HIENHGCL_01761	5.73e-202	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HIENHGCL_01762	2.68e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HIENHGCL_01763	2.22e-09	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
HIENHGCL_01764	1.71e-226	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
HIENHGCL_01765	1.86e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIENHGCL_01766	8.07e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HIENHGCL_01769	2.37e-210	-	-	-	-	-	-	-	-
HIENHGCL_01770	5.77e-214	-	-	-	-	-	-	-	-
HIENHGCL_01771	7.72e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01772	7.05e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HIENHGCL_01773	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HIENHGCL_01774	1.71e-301	ynbB	-	-	P	-	-	-	aluminum resistance
HIENHGCL_01775	8.27e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIENHGCL_01776	1.48e-90	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HIENHGCL_01777	4.01e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HIENHGCL_01778	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HIENHGCL_01779	3.23e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIENHGCL_01780	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HIENHGCL_01781	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HIENHGCL_01782	0.0	-	-	-	S	-	-	-	membrane
HIENHGCL_01783	2.46e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HIENHGCL_01784	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HIENHGCL_01785	1.06e-69	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HIENHGCL_01786	3.51e-17	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HIENHGCL_01787	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HIENHGCL_01788	1.6e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HIENHGCL_01789	3.63e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIENHGCL_01790	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIENHGCL_01791	2.59e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIENHGCL_01792	1.24e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HIENHGCL_01793	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIENHGCL_01794	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HIENHGCL_01795	1.89e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIENHGCL_01796	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HIENHGCL_01797	6.08e-164	csrR	-	-	K	-	-	-	response regulator
HIENHGCL_01798	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HIENHGCL_01799	9.35e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HIENHGCL_01800	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIENHGCL_01801	4.06e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HIENHGCL_01802	8.11e-159	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIENHGCL_01803	4.26e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HIENHGCL_01804	1.66e-120	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HIENHGCL_01805	4.78e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HIENHGCL_01806	8.82e-241	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIENHGCL_01807	4.31e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIENHGCL_01808	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HIENHGCL_01809	9.48e-95	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIENHGCL_01810	1.92e-118	-	-	-	-	-	-	-	-
HIENHGCL_01811	1.39e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HIENHGCL_01812	2.67e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIENHGCL_01813	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIENHGCL_01814	5.35e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HIENHGCL_01815	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HIENHGCL_01816	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIENHGCL_01817	5.52e-139	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIENHGCL_01818	6.72e-205	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIENHGCL_01819	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIENHGCL_01820	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HIENHGCL_01821	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HIENHGCL_01822	3.61e-144	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIENHGCL_01823	3.52e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HIENHGCL_01824	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIENHGCL_01825	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIENHGCL_01826	1.15e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIENHGCL_01827	1.88e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIENHGCL_01828	1.24e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HIENHGCL_01829	1.85e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIENHGCL_01830	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIENHGCL_01831	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HIENHGCL_01832	1.9e-160	-	-	-	C	-	-	-	Flavodoxin
HIENHGCL_01833	5.58e-192	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HIENHGCL_01834	2.68e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIENHGCL_01835	2.76e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HIENHGCL_01836	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
HIENHGCL_01837	2.45e-227	-	-	-	S	-	-	-	SLAP domain
HIENHGCL_01838	6.19e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIENHGCL_01839	3.12e-273	pbpX1	-	-	V	-	-	-	Beta-lactamase
HIENHGCL_01840	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HIENHGCL_01841	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HIENHGCL_01842	3.08e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HIENHGCL_01843	5.27e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIENHGCL_01844	8.28e-15	-	-	-	S	-	-	-	interspecies interaction between organisms
HIENHGCL_01845	1.63e-172	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HIENHGCL_01846	9.66e-41	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HIENHGCL_01847	1.15e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HIENHGCL_01848	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HIENHGCL_01849	1.29e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIENHGCL_01850	3.82e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HIENHGCL_01851	3.51e-170	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIENHGCL_01852	8.29e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIENHGCL_01853	6.35e-69	-	-	-	-	-	-	-	-
HIENHGCL_01854	2.79e-313	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HIENHGCL_01855	9.67e-22	-	-	-	-	-	-	-	-
HIENHGCL_01856	2.37e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HIENHGCL_01857	2e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HIENHGCL_01858	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HIENHGCL_01859	9.95e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HIENHGCL_01860	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HIENHGCL_01861	2.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HIENHGCL_01862	1.4e-196	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HIENHGCL_01863	4.34e-45	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
HIENHGCL_01864	5.78e-208	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
HIENHGCL_01865	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIENHGCL_01866	2.01e-205	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HIENHGCL_01869	1.63e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
HIENHGCL_01870	4.41e-92	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HIENHGCL_01871	4.37e-43	-	-	-	-	-	-	-	-
HIENHGCL_01872	3.32e-98	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIENHGCL_01873	4.19e-182	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIENHGCL_01874	1.45e-42	-	-	-	-	-	-	-	-
HIENHGCL_01875	1.16e-234	-	-	-	EP	-	-	-	Plasmid replication protein
HIENHGCL_01876	4.15e-120	-	-	-	-	-	-	-	-
HIENHGCL_01877	7.23e-264	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIENHGCL_01878	1.08e-71	-	-	-	-	-	-	-	-
HIENHGCL_01879	2.93e-235	-	-	-	-	-	-	-	-
HIENHGCL_01880	2.41e-77	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HIENHGCL_01881	7.47e-133	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HIENHGCL_01883	3.58e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HIENHGCL_01884	1.47e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
HIENHGCL_01885	1.38e-33	-	-	-	S	-	-	-	CsbD-like
HIENHGCL_01886	1.09e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HIENHGCL_01887	1.96e-225	degV1	-	-	S	-	-	-	DegV family
HIENHGCL_01888	1e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HIENHGCL_01889	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HIENHGCL_01890	6.96e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HIENHGCL_01891	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HIENHGCL_01892	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIENHGCL_01893	8.43e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIENHGCL_01894	9.55e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HIENHGCL_01895	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIENHGCL_01896	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIENHGCL_01897	3.1e-269	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIENHGCL_01898	6.15e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HIENHGCL_01899	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIENHGCL_01900	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIENHGCL_01901	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HIENHGCL_01902	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIENHGCL_01903	2.31e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIENHGCL_01904	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIENHGCL_01905	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIENHGCL_01906	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HIENHGCL_01907	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIENHGCL_01908	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HIENHGCL_01909	5.17e-273	-	-	-	-	-	-	-	-
HIENHGCL_01910	1.78e-26	-	-	-	-	-	-	-	-
HIENHGCL_01911	6.65e-153	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HIENHGCL_01912	6.11e-168	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HIENHGCL_01913	2.91e-234	-	-	-	S	-	-	-	DUF218 domain
HIENHGCL_01914	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HIENHGCL_01915	1.09e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HIENHGCL_01916	1.77e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
HIENHGCL_01917	6.78e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HIENHGCL_01918	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIENHGCL_01919	2.47e-32	-	-	-	-	-	-	-	-
HIENHGCL_01920	8.03e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIENHGCL_01921	3.51e-209	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIENHGCL_01922	8.04e-168	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIENHGCL_01923	3.14e-226	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HIENHGCL_01924	4.08e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIENHGCL_01925	1.37e-58	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HIENHGCL_01926	4.2e-75	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance