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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLHLFFPK_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLHLFFPK_00002	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLHLFFPK_00003	5.33e-30	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HLHLFFPK_00004	7.88e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLHLFFPK_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHLFFPK_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHLFFPK_00007	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLHLFFPK_00008	5.89e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLHLFFPK_00009	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLHLFFPK_00010	1.42e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLHLFFPK_00011	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLHLFFPK_00012	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLHLFFPK_00013	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLHLFFPK_00014	2.99e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HLHLFFPK_00015	1.39e-279	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HLHLFFPK_00016	0.0	-	-	-	-	-	-	-	-
HLHLFFPK_00018	8.34e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HLHLFFPK_00019	1.69e-77	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
HLHLFFPK_00020	4.15e-232	-	-	-	-	-	-	-	-
HLHLFFPK_00021	3.11e-71	-	-	-	-	-	-	-	-
HLHLFFPK_00022	2.31e-167	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLHLFFPK_00023	4.15e-120	-	-	-	-	-	-	-	-
HLHLFFPK_00024	1.15e-105	-	-	-	EP	-	-	-	Plasmid replication protein
HLHLFFPK_00025	6.3e-137	-	-	-	EP	-	-	-	Plasmid replication protein
HLHLFFPK_00026	1.45e-42	-	-	-	-	-	-	-	-
HLHLFFPK_00027	8.82e-276	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHLFFPK_00028	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLHLFFPK_00030	9.78e-317	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_00031	2.35e-255	-	-	-	S	-	-	-	Sterol carrier protein domain
HLHLFFPK_00032	4.23e-213	-	-	-	I	-	-	-	Acyltransferase
HLHLFFPK_00033	7.46e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLHLFFPK_00034	8.33e-185	-	-	-	K	-	-	-	Helix-turn-helix domain
HLHLFFPK_00035	7.74e-257	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
HLHLFFPK_00036	3.22e-243	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00037	8.09e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HLHLFFPK_00038	4.52e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLHLFFPK_00039	3.05e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HLHLFFPK_00040	1.07e-23	-	-	-	-	-	-	-	-
HLHLFFPK_00041	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HLHLFFPK_00042	3.37e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HLHLFFPK_00043	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HLHLFFPK_00044	9.36e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHLFFPK_00045	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLHLFFPK_00046	1.32e-157	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HLHLFFPK_00047	2.77e-248	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00048	4.72e-212	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLHLFFPK_00049	1.5e-20	-	-	-	S	-	-	-	CsbD-like
HLHLFFPK_00050	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
HLHLFFPK_00051	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLHLFFPK_00052	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLHLFFPK_00053	5.56e-177	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHLFFPK_00055	1.77e-22	-	-	-	-	-	-	-	-
HLHLFFPK_00056	1.02e-35	-	-	-	-	-	-	-	-
HLHLFFPK_00057	6.19e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
HLHLFFPK_00058	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HLHLFFPK_00059	4.6e-271	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHLFFPK_00060	8.92e-136	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLHLFFPK_00061	1.12e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHLFFPK_00062	0.0	-	-	-	S	-	-	-	domain, Protein
HLHLFFPK_00063	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHLFFPK_00064	0.0	-	-	-	M	-	-	-	domain protein
HLHLFFPK_00065	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HLHLFFPK_00066	1.37e-220	-	-	-	K	-	-	-	LysR substrate binding domain
HLHLFFPK_00067	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLHLFFPK_00068	7.7e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLHLFFPK_00069	1.09e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLHLFFPK_00070	8.35e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLHLFFPK_00071	5.19e-111	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLHLFFPK_00072	5.29e-238	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HLHLFFPK_00073	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00074	7.19e-314	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00075	3.48e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HLHLFFPK_00076	2.24e-239	-	-	-	M	-	-	-	Glycosyl transferase family 8
HLHLFFPK_00077	3.43e-234	-	-	-	M	-	-	-	Glycosyl transferase family 8
HLHLFFPK_00078	2.52e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HLHLFFPK_00079	3.43e-189	-	-	-	I	-	-	-	Acyl-transferase
HLHLFFPK_00081	9.78e-317	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_00083	1.75e-166	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLHLFFPK_00084	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLHLFFPK_00085	0.0	yycH	-	-	S	-	-	-	YycH protein
HLHLFFPK_00086	1.49e-186	yycI	-	-	S	-	-	-	YycH protein
HLHLFFPK_00087	8.73e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HLHLFFPK_00088	6.78e-236	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HLHLFFPK_00089	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLHLFFPK_00090	1.09e-142	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLHLFFPK_00091	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00092	5.59e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLHLFFPK_00093	5.14e-216	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLHLFFPK_00094	2.96e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLHLFFPK_00095	2.67e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HLHLFFPK_00096	4.27e-236	ysdE	-	-	P	-	-	-	Citrate transporter
HLHLFFPK_00097	7.84e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HLHLFFPK_00098	1.14e-23	-	-	-	-	-	-	-	-
HLHLFFPK_00099	6.23e-151	-	-	-	-	-	-	-	-
HLHLFFPK_00101	4.29e-311	-	-	-	M	-	-	-	Glycosyl transferase
HLHLFFPK_00102	4.96e-270	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HLHLFFPK_00103	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HLHLFFPK_00104	2.05e-227	-	-	-	L	-	-	-	HNH nucleases
HLHLFFPK_00105	5.01e-61	-	-	-	-	-	-	-	-
HLHLFFPK_00106	4.83e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00107	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00108	6.19e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLHLFFPK_00109	4.1e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HLHLFFPK_00110	2.41e-165	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HLHLFFPK_00111	6.09e-113	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HLHLFFPK_00112	6.37e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HLHLFFPK_00113	1.28e-103	-	-	-	-	-	-	-	-
HLHLFFPK_00114	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHLFFPK_00115	5.18e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HLHLFFPK_00116	7.39e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLHLFFPK_00117	5.53e-180	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHLFFPK_00119	2.02e-220	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HLHLFFPK_00120	5.52e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HLHLFFPK_00121	3.44e-161	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLHLFFPK_00122	1.13e-81	-	-	-	-	-	-	-	-
HLHLFFPK_00123	6.1e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHLFFPK_00124	1.6e-305	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLHLFFPK_00125	1.01e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHLFFPK_00126	1.14e-161	-	-	-	-	-	-	-	-
HLHLFFPK_00127	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HLHLFFPK_00128	3.19e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLHLFFPK_00129	1.06e-132	-	-	-	-	-	-	-	-
HLHLFFPK_00130	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLHLFFPK_00131	4.73e-215	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HLHLFFPK_00132	2.4e-157	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HLHLFFPK_00133	2.1e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLHLFFPK_00134	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HLHLFFPK_00135	2.69e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HLHLFFPK_00136	1.44e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HLHLFFPK_00137	5.34e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLHLFFPK_00138	9.66e-110	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLHLFFPK_00139	8.1e-191	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HLHLFFPK_00140	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HLHLFFPK_00141	2.66e-88	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLHLFFPK_00142	8.42e-281	-	-	-	S	-	-	-	zinc-ribbon domain
HLHLFFPK_00143	1.56e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HLHLFFPK_00144	1.76e-128	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLHLFFPK_00145	3.53e-169	-	-	-	K	-	-	-	UTRA domain
HLHLFFPK_00146	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLHLFFPK_00147	6.03e-114	usp5	-	-	T	-	-	-	universal stress protein
HLHLFFPK_00149	1.16e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HLHLFFPK_00150	1.28e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HLHLFFPK_00151	1.11e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLHLFFPK_00152	6.11e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLHLFFPK_00153	3.38e-109	-	-	-	-	-	-	-	-
HLHLFFPK_00154	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLHLFFPK_00155	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLHLFFPK_00156	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HLHLFFPK_00157	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HLHLFFPK_00158	1.51e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLHLFFPK_00159	6.48e-136	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLHLFFPK_00160	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HLHLFFPK_00161	7.1e-291	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00162	4.89e-237	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HLHLFFPK_00163	0.0	-	-	-	D	-	-	-	transport
HLHLFFPK_00164	1.33e-174	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLHLFFPK_00165	7.3e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLHLFFPK_00166	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLHLFFPK_00167	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLHLFFPK_00168	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HLHLFFPK_00169	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HLHLFFPK_00170	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HLHLFFPK_00171	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HLHLFFPK_00172	4.33e-95	-	-	-	-	-	-	-	-
HLHLFFPK_00173	5.83e-176	-	-	-	-	-	-	-	-
HLHLFFPK_00174	3.41e-37	-	-	-	-	-	-	-	-
HLHLFFPK_00175	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HLHLFFPK_00176	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHLFFPK_00177	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HLHLFFPK_00178	1.13e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLHLFFPK_00179	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HLHLFFPK_00180	1.01e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLHLFFPK_00181	8.33e-182	-	-	-	-	-	-	-	-
HLHLFFPK_00182	3.27e-191	-	-	-	-	-	-	-	-
HLHLFFPK_00183	2.4e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HLHLFFPK_00184	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHLFFPK_00185	1.45e-60	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HLHLFFPK_00186	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLHLFFPK_00187	9.65e-95	-	-	-	S	-	-	-	GtrA-like protein
HLHLFFPK_00188	7.72e-228	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HLHLFFPK_00189	6.21e-152	-	-	-	-	-	-	-	-
HLHLFFPK_00190	3.83e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLHLFFPK_00191	9.65e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HLHLFFPK_00192	1.59e-268	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHLFFPK_00193	1.2e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLHLFFPK_00194	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HLHLFFPK_00195	1.86e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLHLFFPK_00197	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HLHLFFPK_00198	2.16e-58	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLHLFFPK_00199	4.07e-170	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HLHLFFPK_00200	5.17e-166	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLHLFFPK_00201	1.41e-189	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLHLFFPK_00202	2.97e-21	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00203	2.95e-143	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00204	6.92e-173	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00205	3.06e-158	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHLFFPK_00206	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HLHLFFPK_00207	2.3e-60	-	-	-	-	-	-	-	-
HLHLFFPK_00208	4.49e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHLFFPK_00209	1.52e-68	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLHLFFPK_00210	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_00211	2.35e-107	-	-	-	-	-	-	-	-
HLHLFFPK_00212	3.64e-306	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_00213	3.42e-167	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HLHLFFPK_00214	7.28e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HLHLFFPK_00215	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_00216	1.15e-174	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HLHLFFPK_00217	3.56e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HLHLFFPK_00218	7.13e-56	-	-	-	-	-	-	-	-
HLHLFFPK_00219	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLHLFFPK_00220	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_00221	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_00222	6.66e-201	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLHLFFPK_00223	8.03e-151	-	-	-	-	-	-	-	-
HLHLFFPK_00225	2.97e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HLHLFFPK_00226	2.46e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHLFFPK_00227	9.68e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HLHLFFPK_00228	3.58e-128	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HLHLFFPK_00229	5.01e-233	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HLHLFFPK_00230	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLHLFFPK_00231	3.86e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HLHLFFPK_00232	4.59e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLHLFFPK_00233	1.15e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLHLFFPK_00234	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HLHLFFPK_00235	1.91e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLHLFFPK_00236	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLHLFFPK_00237	2.27e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHLFFPK_00238	1.01e-225	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HLHLFFPK_00239	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HLHLFFPK_00240	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLHLFFPK_00241	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLHLFFPK_00242	4.64e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HLHLFFPK_00243	3.21e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00244	1.48e-289	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLHLFFPK_00245	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLHLFFPK_00246	3.99e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00247	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HLHLFFPK_00248	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHLFFPK_00249	4.71e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HLHLFFPK_00250	1.03e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLHLFFPK_00251	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLHLFFPK_00252	4.39e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLHLFFPK_00253	1.6e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HLHLFFPK_00254	9.63e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLHLFFPK_00255	2.16e-167	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HLHLFFPK_00256	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLHLFFPK_00257	3.64e-76	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHLFFPK_00258	1.32e-188	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLHLFFPK_00259	1.8e-36	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HLHLFFPK_00261	2.91e-139	-	-	-	K	-	-	-	transcriptional regulator
HLHLFFPK_00262	1.79e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLHLFFPK_00263	4.22e-219	-	-	-	K	-	-	-	Helix-turn-helix
HLHLFFPK_00264	3.76e-145	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLHLFFPK_00265	2.31e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHLFFPK_00266	1.3e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HLHLFFPK_00267	1.16e-142	-	-	-	S	-	-	-	Membrane
HLHLFFPK_00268	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00269	5.14e-103	-	-	-	S	-	-	-	Membrane
HLHLFFPK_00270	1.75e-314	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_00271	1.62e-194	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_00272	9.97e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HLHLFFPK_00273	9.54e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHLFFPK_00274	3.27e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLHLFFPK_00275	3.6e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHLFFPK_00276	2.63e-73	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_00277	2.53e-123	-	-	-	-	-	-	-	-
HLHLFFPK_00278	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLHLFFPK_00279	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHLFFPK_00280	2.49e-259	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLHLFFPK_00281	7.55e-53	-	-	-	-	-	-	-	-
HLHLFFPK_00282	9.97e-105	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLHLFFPK_00283	4.04e-103	-	-	-	-	-	-	-	-
HLHLFFPK_00284	1.46e-42	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHLFFPK_00285	1.14e-99	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HLHLFFPK_00286	1.29e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HLHLFFPK_00287	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHLFFPK_00288	2.03e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLHLFFPK_00289	5.42e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLHLFFPK_00290	3.67e-184	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLHLFFPK_00291	1.04e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00292	0.0	-	-	-	E	-	-	-	amino acid
HLHLFFPK_00293	8.98e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLHLFFPK_00294	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLHLFFPK_00295	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLHLFFPK_00296	5.86e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLHLFFPK_00297	2.57e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLHLFFPK_00298	3.03e-158	-	-	-	S	-	-	-	(CBS) domain
HLHLFFPK_00299	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLHLFFPK_00300	4.45e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLHLFFPK_00301	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLHLFFPK_00302	3.62e-46	yabO	-	-	J	-	-	-	S4 domain protein
HLHLFFPK_00303	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLHLFFPK_00304	4.65e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HLHLFFPK_00305	3.44e-311	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLHLFFPK_00306	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLHLFFPK_00307	0.0	-	-	-	S	-	-	-	membrane
HLHLFFPK_00308	0.0	-	-	-	S	-	-	-	membrane
HLHLFFPK_00309	1.92e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLHLFFPK_00310	3.21e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLHLFFPK_00311	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLHLFFPK_00314	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLHLFFPK_00315	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHLFFPK_00316	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHLFFPK_00317	8.18e-141	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HLHLFFPK_00318	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLHLFFPK_00319	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLHLFFPK_00320	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLHLFFPK_00321	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLHLFFPK_00322	8.75e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLHLFFPK_00323	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLHLFFPK_00324	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLHLFFPK_00325	1.99e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLHLFFPK_00326	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLHLFFPK_00327	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLHLFFPK_00328	1.29e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLHLFFPK_00329	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLHLFFPK_00330	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLHLFFPK_00331	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLHLFFPK_00332	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLHLFFPK_00333	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLHLFFPK_00334	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLHLFFPK_00335	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLHLFFPK_00336	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLHLFFPK_00337	1.76e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLHLFFPK_00338	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLHLFFPK_00339	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLHLFFPK_00340	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLHLFFPK_00341	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLHLFFPK_00342	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLHLFFPK_00343	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLHLFFPK_00344	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLHLFFPK_00345	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLHLFFPK_00346	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLHLFFPK_00347	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLHLFFPK_00348	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHLFFPK_00349	1.1e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLHLFFPK_00350	1.63e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHLFFPK_00351	4.05e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHLFFPK_00352	7.09e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHLFFPK_00353	1.29e-191	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLHLFFPK_00354	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLHLFFPK_00355	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLHLFFPK_00357	2.8e-289	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HLHLFFPK_00358	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HLHLFFPK_00359	5.89e-90	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HLHLFFPK_00360	1.88e-192	-	-	-	GM	-	-	-	NmrA-like family
HLHLFFPK_00361	4.42e-142	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HLHLFFPK_00362	3.17e-166	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HLHLFFPK_00363	4.17e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLHLFFPK_00364	3.4e-198	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HLHLFFPK_00365	9.99e-53	-	-	-	-	-	-	-	-
HLHLFFPK_00366	2.39e-16	-	-	-	-	-	-	-	-
HLHLFFPK_00367	7.96e-159	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHLFFPK_00368	1.2e-236	-	-	-	S	-	-	-	AAA domain
HLHLFFPK_00369	2.68e-236	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHLFFPK_00370	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHLFFPK_00371	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
HLHLFFPK_00372	2.28e-272	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
HLHLFFPK_00373	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
HLHLFFPK_00374	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HLHLFFPK_00375	3.04e-199	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
HLHLFFPK_00376	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLHLFFPK_00377	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLHLFFPK_00378	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLHLFFPK_00380	1.68e-31	-	-	-	UW	-	-	-	Tetratricopeptide repeat
HLHLFFPK_00381	3.35e-213	-	-	-	S	-	-	-	glycosyl transferase family 2
HLHLFFPK_00382	2.19e-250	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLHLFFPK_00383	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLHLFFPK_00384	3.12e-239	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHLFFPK_00385	1.1e-132	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HLHLFFPK_00386	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLHLFFPK_00387	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLHLFFPK_00388	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHLFFPK_00389	5.57e-104	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLHLFFPK_00390	1.62e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHLFFPK_00391	3.08e-115	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
HLHLFFPK_00392	5.9e-46	-	-	-	-	-	-	-	-
HLHLFFPK_00393	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLHLFFPK_00394	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLHLFFPK_00395	1.18e-291	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00396	2.23e-238	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLHLFFPK_00397	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLHLFFPK_00398	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLHLFFPK_00399	6.09e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLHLFFPK_00400	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLHLFFPK_00401	2.9e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLHLFFPK_00402	1.96e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00403	6.39e-150	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HLHLFFPK_00404	6.64e-187	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_00405	7.87e-125	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLHLFFPK_00406	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLHLFFPK_00407	2.69e-182	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HLHLFFPK_00408	3.25e-44	-	-	-	-	-	-	-	-
HLHLFFPK_00409	4.73e-146	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HLHLFFPK_00410	3.9e-30	-	-	-	-	-	-	-	-
HLHLFFPK_00411	1.52e-190	-	-	-	-	-	-	-	-
HLHLFFPK_00412	9.83e-66	-	-	-	S	-	-	-	Protein conserved in bacteria
HLHLFFPK_00413	4.11e-110	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLHLFFPK_00414	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHLFFPK_00415	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLHLFFPK_00416	2.53e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLHLFFPK_00417	3.03e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLHLFFPK_00418	2.92e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLHLFFPK_00419	1.24e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HLHLFFPK_00420	2.58e-193	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLHLFFPK_00421	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLHLFFPK_00422	2.81e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLHLFFPK_00423	5.47e-179	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HLHLFFPK_00424	2.13e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLHLFFPK_00425	1.44e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HLHLFFPK_00426	2.49e-122	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HLHLFFPK_00427	5.57e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLHLFFPK_00428	2.51e-304	-	-	-	D	-	-	-	nuclear chromosome segregation
HLHLFFPK_00429	7.14e-54	-	-	-	-	-	-	-	-
HLHLFFPK_00430	1.16e-148	-	-	-	-	-	-	-	-
HLHLFFPK_00431	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHLFFPK_00432	4.91e-241	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHLFFPK_00433	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLHLFFPK_00434	1.98e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLHLFFPK_00435	4.51e-184	-	-	-	L	-	-	-	oxidized base lesion DNA N-glycosylase activity
HLHLFFPK_00436	2e-103	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HLHLFFPK_00437	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00438	5.74e-208	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLHLFFPK_00439	4.28e-177	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLHLFFPK_00440	1.29e-172	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLHLFFPK_00441	3.03e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHLFFPK_00442	7.76e-108	-	-	-	-	-	-	-	-
HLHLFFPK_00443	1.47e-315	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_00444	2.13e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLHLFFPK_00445	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLHLFFPK_00446	6.45e-201	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00447	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLHLFFPK_00448	9.68e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLHLFFPK_00449	3.54e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLHLFFPK_00450	5.72e-104	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHLFFPK_00451	6.76e-168	-	-	-	S	-	-	-	membrane
HLHLFFPK_00452	6.45e-201	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00454	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLHLFFPK_00455	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLHLFFPK_00456	1.53e-18	-	-	-	K	-	-	-	Helix-turn-helix domain
HLHLFFPK_00457	9.83e-148	-	-	-	-	-	-	-	-
HLHLFFPK_00459	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HLHLFFPK_00460	9.81e-20	-	-	-	-	-	-	-	-
HLHLFFPK_00461	2.29e-42	-	-	-	-	-	-	-	-
HLHLFFPK_00462	5.79e-90	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLHLFFPK_00463	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLHLFFPK_00464	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLHLFFPK_00465	3.1e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLHLFFPK_00466	1.63e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLHLFFPK_00467	2.39e-75	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLHLFFPK_00468	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLHLFFPK_00469	4.21e-266	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLHLFFPK_00470	1.24e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HLHLFFPK_00471	7.97e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLHLFFPK_00472	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLHLFFPK_00473	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLHLFFPK_00474	1.68e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLHLFFPK_00475	3.49e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLHLFFPK_00476	1.96e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
HLHLFFPK_00477	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLHLFFPK_00478	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLHLFFPK_00479	3.65e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLHLFFPK_00480	1.23e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLHLFFPK_00481	3.6e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLHLFFPK_00482	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHLFFPK_00483	2.5e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLHLFFPK_00484	1.21e-177	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HLHLFFPK_00485	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLHLFFPK_00486	8.01e-66	-	-	-	-	-	-	-	-
HLHLFFPK_00487	2.55e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLHLFFPK_00488	4.41e-224	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLHLFFPK_00489	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HLHLFFPK_00490	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HLHLFFPK_00491	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLHLFFPK_00492	1.15e-73	-	-	-	-	-	-	-	-
HLHLFFPK_00493	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLHLFFPK_00494	1.62e-123	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HLHLFFPK_00495	1.2e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLHLFFPK_00496	3.32e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HLHLFFPK_00497	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HLHLFFPK_00498	7.44e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLHLFFPK_00499	8.2e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HLHLFFPK_00505	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HLHLFFPK_00506	9.89e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLHLFFPK_00507	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_00508	6.9e-150	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HLHLFFPK_00509	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHLFFPK_00510	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLHLFFPK_00511	1.55e-275	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HLHLFFPK_00512	1.68e-175	-	-	-	-	-	-	-	-
HLHLFFPK_00513	2.03e-188	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLHLFFPK_00514	3.93e-220	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLHLFFPK_00515	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLHLFFPK_00516	6.29e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HLHLFFPK_00517	6.07e-60	-	-	-	-	-	-	-	-
HLHLFFPK_00518	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
HLHLFFPK_00519	1.13e-71	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLHLFFPK_00520	1.79e-106	ptsB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLHLFFPK_00521	3.18e-176	ptsC	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HLHLFFPK_00522	2.69e-190	ptsD	-	-	G	ko:K02796,ko:K19509	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HLHLFFPK_00523	8.75e-146	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HLHLFFPK_00524	2.64e-168	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HLHLFFPK_00526	8.35e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHLFFPK_00527	7.48e-162	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
HLHLFFPK_00528	1.57e-143	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HLHLFFPK_00529	1.71e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HLHLFFPK_00530	5.29e-282	-	-	-	P	-	-	-	Voltage gated chloride channel
HLHLFFPK_00531	4.95e-246	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HLHLFFPK_00532	7.34e-129	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HLHLFFPK_00533	2.4e-207	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLHLFFPK_00534	3.77e-174	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
HLHLFFPK_00535	9.83e-185	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLHLFFPK_00536	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HLHLFFPK_00537	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HLHLFFPK_00538	3.76e-89	-	-	-	-	-	-	-	-
HLHLFFPK_00540	2.19e-22	-	-	-	-	-	-	-	-
HLHLFFPK_00541	7.53e-107	-	-	-	K	-	-	-	acetyltransferase
HLHLFFPK_00542	1.98e-258	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLHLFFPK_00543	1.1e-187	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLHLFFPK_00544	1.34e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
HLHLFFPK_00545	1.9e-191	-	-	-	S	-	-	-	hydrolase
HLHLFFPK_00546	3.45e-203	-	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_00547	1.18e-308	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HLHLFFPK_00548	5.79e-170	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HLHLFFPK_00549	3.14e-94	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HLHLFFPK_00550	1.17e-136	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HLHLFFPK_00551	4.47e-19	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
HLHLFFPK_00552	1.02e-121	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
HLHLFFPK_00553	1.62e-71	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HLHLFFPK_00554	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HLHLFFPK_00555	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_00556	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLHLFFPK_00557	1.15e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HLHLFFPK_00558	0.0	-	-	-	E	-	-	-	Phospholipase B
HLHLFFPK_00559	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLHLFFPK_00560	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
HLHLFFPK_00561	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HLHLFFPK_00562	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLHLFFPK_00563	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
HLHLFFPK_00564	1.32e-196	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
HLHLFFPK_00565	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HLHLFFPK_00566	6.1e-311	-	-	-	E	-	-	-	amino acid
HLHLFFPK_00567	3.61e-269	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HLHLFFPK_00568	1.06e-37	-	-	-	-	-	-	-	-
HLHLFFPK_00569	6.45e-91	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLHLFFPK_00570	2.04e-107	-	-	-	-	-	-	-	-
HLHLFFPK_00571	7.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HLHLFFPK_00573	2.13e-149	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00574	9.94e-166	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HLHLFFPK_00575	1.47e-315	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_00576	1.56e-266	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HLHLFFPK_00577	1.02e-99	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HLHLFFPK_00578	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HLHLFFPK_00579	0.0	-	-	-	E	-	-	-	Peptidase family C69
HLHLFFPK_00580	3.81e-275	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HLHLFFPK_00581	7.77e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHLFFPK_00582	5.97e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HLHLFFPK_00583	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00584	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HLHLFFPK_00585	1.1e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_00586	6.35e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00587	3.69e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_00588	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00589	3.24e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00590	1.68e-85	-	-	-	-	-	-	-	-
HLHLFFPK_00591	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLHLFFPK_00592	4.77e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HLHLFFPK_00593	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLHLFFPK_00594	8.35e-110	-	-	-	S	-	-	-	Putative adhesin
HLHLFFPK_00596	6.41e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLHLFFPK_00598	2.32e-260	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLHLFFPK_00599	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_00600	9.89e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLHLFFPK_00601	4.71e-285	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HLHLFFPK_00602	1.89e-185	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLHLFFPK_00603	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLHLFFPK_00604	6.99e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HLHLFFPK_00605	4.62e-31	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
HLHLFFPK_00609	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00610	6.15e-40	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLHLFFPK_00611	1.2e-127	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HLHLFFPK_00613	1.09e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HLHLFFPK_00614	3.44e-283	-	-	-	S	-	-	-	CAAX protease self-immunity
HLHLFFPK_00618	6.77e-71	-	-	-	S	-	-	-	Enterocin A Immunity
HLHLFFPK_00620	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HLHLFFPK_00621	7.86e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
HLHLFFPK_00622	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00623	3.39e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00624	1.13e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHLFFPK_00625	2.73e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLHLFFPK_00626	8.44e-217	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLHLFFPK_00627	1.44e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HLHLFFPK_00628	4.68e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLHLFFPK_00629	4.62e-183	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLHLFFPK_00630	8.28e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HLHLFFPK_00631	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLHLFFPK_00632	1.98e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLHLFFPK_00633	4.72e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLHLFFPK_00634	7.73e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLHLFFPK_00635	9.72e-225	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HLHLFFPK_00636	1.39e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HLHLFFPK_00637	6.15e-69	-	-	-	S	-	-	-	Enterocin A Immunity
HLHLFFPK_00638	3.01e-180	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HLHLFFPK_00639	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HLHLFFPK_00640	5.05e-153	-	-	-	C	-	-	-	nitroreductase
HLHLFFPK_00641	7.49e-168	-	-	-	-	-	-	-	-
HLHLFFPK_00642	4.03e-301	yhdP	-	-	S	-	-	-	Transporter associated domain
HLHLFFPK_00643	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHLFFPK_00644	1.39e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
HLHLFFPK_00645	1.91e-175	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HLHLFFPK_00646	5.69e-280	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HLHLFFPK_00647	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_00650	1.05e-274	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLHLFFPK_00651	6.2e-114	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HLHLFFPK_00652	1.36e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLHLFFPK_00653	2.97e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HLHLFFPK_00654	2.72e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLHLFFPK_00655	2.45e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLHLFFPK_00656	6.12e-232	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00657	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLHLFFPK_00658	3.2e-91	-	-	-	O	-	-	-	OsmC-like protein
HLHLFFPK_00659	1.84e-210	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHLFFPK_00660	2.44e-148	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HLHLFFPK_00661	5.01e-150	dltr	-	-	K	-	-	-	response regulator
HLHLFFPK_00662	3.85e-292	sptS	-	-	T	-	-	-	Histidine kinase
HLHLFFPK_00663	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLHLFFPK_00664	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HLHLFFPK_00665	1.98e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLHLFFPK_00667	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HLHLFFPK_00668	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLHLFFPK_00669	8.07e-91	-	-	-	-	-	-	-	-
HLHLFFPK_00670	8.04e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HLHLFFPK_00671	1.98e-190	-	-	-	M	-	-	-	Glycosyl transferase family 2
HLHLFFPK_00672	2.37e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HLHLFFPK_00673	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLHLFFPK_00674	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLHLFFPK_00675	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_00676	2.46e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HLHLFFPK_00677	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLHLFFPK_00680	1.67e-104	-	-	-	M	-	-	-	Sortase family
HLHLFFPK_00681	2.08e-13	-	-	-	GK	-	-	-	ROK family
HLHLFFPK_00682	5.65e-171	-	-	-	GK	-	-	-	ROK family
HLHLFFPK_00683	2.26e-80	-	-	-	K	-	-	-	AraC-like ligand binding domain
HLHLFFPK_00684	2.46e-74	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLHLFFPK_00685	6.33e-226	-	-	-	I	-	-	-	Carboxylesterase family
HLHLFFPK_00686	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HLHLFFPK_00687	6.43e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HLHLFFPK_00688	1.7e-110	-	-	-	-	-	-	-	-
HLHLFFPK_00689	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HLHLFFPK_00690	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HLHLFFPK_00691	8.45e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HLHLFFPK_00692	1.87e-84	-	-	-	-	-	-	-	-
HLHLFFPK_00693	1.17e-17	-	-	-	-	-	-	-	-
HLHLFFPK_00694	3.98e-271	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HLHLFFPK_00695	2.81e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLHLFFPK_00696	1.75e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HLHLFFPK_00697	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLHLFFPK_00698	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLHLFFPK_00699	1.57e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLHLFFPK_00700	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLHLFFPK_00701	7.32e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HLHLFFPK_00702	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLHLFFPK_00703	2.29e-190	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLHLFFPK_00704	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHLFFPK_00705	2.74e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHLFFPK_00706	4.89e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLHLFFPK_00707	1.03e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HLHLFFPK_00708	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLHLFFPK_00709	7.04e-63	-	-	-	-	-	-	-	-
HLHLFFPK_00710	3.6e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLHLFFPK_00711	3.3e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLHLFFPK_00712	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLHLFFPK_00713	4.41e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLHLFFPK_00714	4.56e-303	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLHLFFPK_00715	3.69e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLHLFFPK_00716	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLHLFFPK_00717	2.16e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLHLFFPK_00718	4.51e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLHLFFPK_00719	9.07e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLHLFFPK_00720	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLHLFFPK_00721	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLHLFFPK_00722	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HLHLFFPK_00723	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLHLFFPK_00724	3.54e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLHLFFPK_00725	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLHLFFPK_00726	9.96e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00727	8.34e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLHLFFPK_00728	3.25e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00729	1.06e-206	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLHLFFPK_00730	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_00731	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_00732	1.83e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLHLFFPK_00733	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLHLFFPK_00734	2.93e-273	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLHLFFPK_00735	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHLFFPK_00736	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLHLFFPK_00737	1.99e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLHLFFPK_00738	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLHLFFPK_00739	9.87e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLHLFFPK_00740	2.14e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLHLFFPK_00741	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLHLFFPK_00742	2.63e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLHLFFPK_00743	2.61e-96	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HLHLFFPK_00744	2.15e-151	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HLHLFFPK_00745	7.82e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLHLFFPK_00746	1.7e-45	ynzC	-	-	S	-	-	-	UPF0291 protein
HLHLFFPK_00747	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HLHLFFPK_00748	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_00749	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_00750	5.39e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HLHLFFPK_00751	1.16e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HLHLFFPK_00752	3.79e-250	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HLHLFFPK_00753	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLHLFFPK_00754	8.74e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLHLFFPK_00755	1.01e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLHLFFPK_00756	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLHLFFPK_00757	2.81e-174	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLHLFFPK_00758	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLHLFFPK_00759	1.09e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLHLFFPK_00760	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLHLFFPK_00761	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHLFFPK_00762	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLHLFFPK_00763	2.72e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLHLFFPK_00764	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HLHLFFPK_00765	1.32e-63	-	-	-	J	-	-	-	ribosomal protein
HLHLFFPK_00766	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLHLFFPK_00767	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLHLFFPK_00768	1.04e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLHLFFPK_00769	1.5e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLHLFFPK_00770	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HLHLFFPK_00771	4.87e-121	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HLHLFFPK_00772	1.13e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLHLFFPK_00773	2.27e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLHLFFPK_00774	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLHLFFPK_00775	1.73e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLHLFFPK_00776	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLHLFFPK_00777	4.45e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HLHLFFPK_00778	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLHLFFPK_00779	5.93e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLHLFFPK_00780	0.0	potE	-	-	E	-	-	-	Amino Acid
HLHLFFPK_00781	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHLFFPK_00782	2.62e-239	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLHLFFPK_00783	1.21e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLHLFFPK_00784	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLHLFFPK_00785	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HLHLFFPK_00786	6.2e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HLHLFFPK_00788	4.39e-133	-	-	-	I	-	-	-	PAP2 superfamily
HLHLFFPK_00789	2.48e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLHLFFPK_00790	2.94e-42	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HLHLFFPK_00791	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HLHLFFPK_00792	1.07e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLHLFFPK_00793	2e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
HLHLFFPK_00794	1.71e-181	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HLHLFFPK_00795	6.82e-94	-	-	-	L	-	-	-	nuclease
HLHLFFPK_00796	1.34e-199	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLHLFFPK_00797	2.07e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLHLFFPK_00798	8.98e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00799	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLHLFFPK_00800	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLHLFFPK_00801	8.88e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLHLFFPK_00802	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLHLFFPK_00803	2.09e-243	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HLHLFFPK_00804	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HLHLFFPK_00805	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HLHLFFPK_00806	3.6e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLHLFFPK_00807	4.09e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HLHLFFPK_00808	1.91e-85	-	-	-	-	-	-	-	-
HLHLFFPK_00809	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLHLFFPK_00810	8.26e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLHLFFPK_00811	9.01e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLHLFFPK_00812	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLHLFFPK_00813	3.88e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHLFFPK_00814	4.29e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLHLFFPK_00815	8.29e-174	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLHLFFPK_00816	5.01e-12	-	-	-	-	-	-	-	-
HLHLFFPK_00817	6.02e-133	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLHLFFPK_00818	2.23e-202	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLHLFFPK_00819	7.17e-154	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HLHLFFPK_00820	6.79e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLHLFFPK_00821	2.53e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLHLFFPK_00822	3.44e-200	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLHLFFPK_00823	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLHLFFPK_00824	5.18e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HLHLFFPK_00825	2.02e-221	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HLHLFFPK_00826	6.87e-114	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLHLFFPK_00827	6.75e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLHLFFPK_00828	2.79e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLHLFFPK_00829	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLHLFFPK_00830	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLHLFFPK_00831	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLHLFFPK_00832	8.64e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLHLFFPK_00834	1.17e-178	-	-	-	-	-	-	-	-
HLHLFFPK_00835	4.37e-119	-	-	-	-	-	-	-	-
HLHLFFPK_00837	5.9e-262	-	-	-	M	-	-	-	domain protein
HLHLFFPK_00838	4.57e-212	-	-	-	S	-	-	-	DNA/RNA non-specific endonuclease
HLHLFFPK_00839	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_00840	9.89e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLHLFFPK_00841	2.91e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HLHLFFPK_00842	7.1e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHLFFPK_00843	2.3e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_00844	1.13e-191	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_00845	1.84e-155	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLHLFFPK_00846	2.24e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLHLFFPK_00847	7.64e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLHLFFPK_00848	5.15e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HLHLFFPK_00849	7.68e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLHLFFPK_00850	7.71e-188	-	-	-	-	-	-	-	-
HLHLFFPK_00851	7.02e-183	-	-	-	-	-	-	-	-
HLHLFFPK_00852	6.46e-49	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_00853	2.06e-192	-	-	-	-	-	-	-	-
HLHLFFPK_00855	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HLHLFFPK_00856	1.1e-49	-	-	-	-	-	-	-	-
HLHLFFPK_00857	4.93e-82	-	-	-	-	-	-	-	-
HLHLFFPK_00858	6.61e-15	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLHLFFPK_00859	2.65e-108	-	-	-	L	-	-	-	transposase activity
HLHLFFPK_00860	5.06e-31	-	-	-	-	-	-	-	-
HLHLFFPK_00861	7.35e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLHLFFPK_00862	7.7e-169	-	-	-	-	-	-	-	-
HLHLFFPK_00863	6.25e-221	-	-	-	-	-	-	-	-
HLHLFFPK_00864	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HLHLFFPK_00865	5.06e-68	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HLHLFFPK_00866	1.38e-230	-	-	-	S	-	-	-	DUF218 domain
HLHLFFPK_00867	6.65e-193	yxeH	-	-	S	-	-	-	hydrolase
HLHLFFPK_00868	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HLHLFFPK_00869	3.18e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLHLFFPK_00870	1.23e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLHLFFPK_00871	1.36e-215	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLHLFFPK_00872	6.39e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLHLFFPK_00873	1.34e-232	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLHLFFPK_00874	5.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLHLFFPK_00875	4.57e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLHLFFPK_00876	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLHLFFPK_00877	3.27e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLHLFFPK_00878	1.28e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
HLHLFFPK_00879	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HLHLFFPK_00880	3.8e-274	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLHLFFPK_00881	4.35e-119	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HLHLFFPK_00882	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00883	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLHLFFPK_00884	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLHLFFPK_00885	5.41e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HLHLFFPK_00886	3.31e-201	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HLHLFFPK_00887	2.72e-238	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HLHLFFPK_00888	0.0	-	-	-	G	-	-	-	isomerase
HLHLFFPK_00889	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
HLHLFFPK_00890	1.57e-196	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLHLFFPK_00891	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLHLFFPK_00892	8.2e-218	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLHLFFPK_00893	2.9e-215	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HLHLFFPK_00894	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
HLHLFFPK_00895	5.07e-151	-	-	-	C	-	-	-	nitroreductase
HLHLFFPK_00896	6.92e-215	-	-	-	C	-	-	-	Oxidoreductase
HLHLFFPK_00897	6.56e-97	-	-	-	S	-	-	-	SnoaL-like domain
HLHLFFPK_00898	1.69e-13	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HLHLFFPK_00899	1.17e-116	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HLHLFFPK_00900	6.48e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLHLFFPK_00902	3.08e-74	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HLHLFFPK_00903	1.44e-98	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HLHLFFPK_00904	1.4e-229	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HLHLFFPK_00905	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HLHLFFPK_00906	1.74e-311	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLHLFFPK_00907	8.89e-269	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLHLFFPK_00908	1.43e-110	yfhC	-	-	C	-	-	-	nitroreductase
HLHLFFPK_00909	4.91e-59	-	-	-	V	-	-	-	ABC transporter transmembrane region
HLHLFFPK_00910	3.17e-277	-	-	-	V	-	-	-	ABC transporter transmembrane region
HLHLFFPK_00911	3.25e-70	-	-	-	-	-	-	-	-
HLHLFFPK_00912	5.13e-80	-	-	-	-	-	-	-	-
HLHLFFPK_00913	1.11e-100	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHLFFPK_00914	9.86e-110	-	-	-	FG	-	-	-	HIT domain
HLHLFFPK_00915	8.86e-62	-	-	-	S	-	-	-	MazG-like family
HLHLFFPK_00916	7.67e-80	-	-	-	-	-	-	-	-
HLHLFFPK_00917	6.76e-152	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLHLFFPK_00918	2.56e-56	-	-	-	-	-	-	-	-
HLHLFFPK_00919	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHLFFPK_00920	4.68e-182	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HLHLFFPK_00921	2.83e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLHLFFPK_00922	2.99e-119	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HLHLFFPK_00923	2.26e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HLHLFFPK_00924	7.72e-181	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLHLFFPK_00925	4.96e-146	-	-	-	-	-	-	-	-
HLHLFFPK_00926	5.01e-106	-	-	-	-	-	-	-	-
HLHLFFPK_00927	4.7e-120	-	-	-	S	-	-	-	AAA domain
HLHLFFPK_00928	1.06e-195	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HLHLFFPK_00929	1.24e-108	-	-	-	F	-	-	-	NUDIX domain
HLHLFFPK_00930	7.18e-07	-	-	-	F	-	-	-	Phosphorylase superfamily
HLHLFFPK_00931	2.72e-191	-	-	-	F	-	-	-	Phosphorylase superfamily
HLHLFFPK_00932	6.17e-193	-	-	-	F	-	-	-	Phosphorylase superfamily
HLHLFFPK_00933	8.85e-111	-	-	-	S	-	-	-	ASCH
HLHLFFPK_00934	9.13e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLHLFFPK_00935	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLHLFFPK_00936	5.97e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HLHLFFPK_00937	5.51e-200	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HLHLFFPK_00938	7.29e-269	-	-	-	G	-	-	-	Transmembrane secretion effector
HLHLFFPK_00939	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HLHLFFPK_00940	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HLHLFFPK_00941	4.72e-240	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLHLFFPK_00942	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HLHLFFPK_00943	2.03e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HLHLFFPK_00944	4.95e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HLHLFFPK_00945	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLHLFFPK_00946	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLHLFFPK_00947	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLHLFFPK_00948	1.32e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HLHLFFPK_00949	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HLHLFFPK_00950	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HLHLFFPK_00951	2.33e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLHLFFPK_00952	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HLHLFFPK_00953	5.29e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLHLFFPK_00954	5.4e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLHLFFPK_00955	2.77e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLHLFFPK_00956	3.8e-274	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLHLFFPK_00957	1.17e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLHLFFPK_00958	6.42e-287	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HLHLFFPK_00959	1.38e-224	degV1	-	-	S	-	-	-	DegV family
HLHLFFPK_00960	1.53e-74	-	-	-	-	-	-	-	-
HLHLFFPK_00961	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HLHLFFPK_00962	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLHLFFPK_00963	4.78e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLHLFFPK_00964	7.66e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLHLFFPK_00965	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLHLFFPK_00966	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HLHLFFPK_00967	1.32e-84	-	-	-	-	-	-	-	-
HLHLFFPK_00968	5.52e-209	-	-	-	S	-	-	-	EDD domain protein, DegV family
HLHLFFPK_00969	1.18e-197	-	-	-	-	-	-	-	-
HLHLFFPK_00970	1.47e-212	lysR	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_00971	9.84e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HLHLFFPK_00972	1.62e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HLHLFFPK_00973	9.62e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLHLFFPK_00974	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLHLFFPK_00975	4.97e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HLHLFFPK_00976	5.65e-229	-	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_00977	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHLFFPK_00978	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHLFFPK_00979	1.62e-149	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLHLFFPK_00980	3.74e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLHLFFPK_00981	4.22e-211	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLHLFFPK_00982	1.09e-141	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLHLFFPK_00983	2.17e-43	-	-	-	-	-	-	-	-
HLHLFFPK_00984	7.3e-216	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HLHLFFPK_00985	2.41e-298	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HLHLFFPK_00986	7.23e-25	lysR	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_00987	5.72e-200	-	-	-	C	-	-	-	Aldo keto reductase
HLHLFFPK_00988	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLHLFFPK_00989	1.87e-92	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HLHLFFPK_00990	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HLHLFFPK_00991	3.65e-100	-	-	-	S	-	-	-	Cupin domain
HLHLFFPK_00992	6.03e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLHLFFPK_00993	9.35e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HLHLFFPK_00995	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_00996	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HLHLFFPK_00997	1.38e-89	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLHLFFPK_00998	2.4e-43	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLHLFFPK_00999	3.2e-30	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLHLFFPK_01000	7.52e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLHLFFPK_01001	0.000705	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHLFFPK_01002	2.71e-180	-	-	-	H	-	-	-	Nodulation protein S (NodS)
HLHLFFPK_01003	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLHLFFPK_01004	1.02e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLHLFFPK_01005	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HLHLFFPK_01006	1.4e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HLHLFFPK_01007	3.7e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLHLFFPK_01008	6.53e-291	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HLHLFFPK_01009	4.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HLHLFFPK_01010	3.64e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLHLFFPK_01011	6.71e-134	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLHLFFPK_01012	2.71e-32	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLHLFFPK_01013	4.12e-156	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLHLFFPK_01014	4.05e-119	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLHLFFPK_01015	5.05e-313	-	-	-	T	-	-	-	GHKL domain
HLHLFFPK_01016	5.04e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HLHLFFPK_01017	3.45e-150	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HLHLFFPK_01018	2.96e-138	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HLHLFFPK_01019	9.63e-70	-	-	-	S	-	-	-	reductase
HLHLFFPK_01020	3.46e-15	-	-	-	S	-	-	-	reductase
HLHLFFPK_01021	2.7e-139	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HLHLFFPK_01022	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HLHLFFPK_01023	8.95e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHLFFPK_01024	7.2e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLHLFFPK_01025	4.14e-174	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HLHLFFPK_01026	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHLFFPK_01027	1.25e-107	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HLHLFFPK_01028	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HLHLFFPK_01029	8.58e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLHLFFPK_01030	1.76e-94	-	-	-	-	-	-	-	-
HLHLFFPK_01032	5.82e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HLHLFFPK_01033	4.81e-124	-	-	-	K	-	-	-	LysR substrate binding domain
HLHLFFPK_01034	3.4e-228	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLHLFFPK_01035	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLHLFFPK_01036	1.9e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLHLFFPK_01037	8.22e-217	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HLHLFFPK_01038	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLHLFFPK_01039	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLHLFFPK_01040	5.91e-197	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HLHLFFPK_01041	2.57e-171	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHLFFPK_01042	1.41e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLHLFFPK_01043	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLHLFFPK_01044	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLHLFFPK_01045	1.05e-192	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HLHLFFPK_01046	2.78e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HLHLFFPK_01047	2.35e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLHLFFPK_01048	1.76e-203	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLHLFFPK_01049	7.47e-76	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HLHLFFPK_01050	6.18e-183	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HLHLFFPK_01051	7.7e-156	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HLHLFFPK_01052	7.29e-81	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HLHLFFPK_01053	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01054	1.02e-71	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HLHLFFPK_01055	7.12e-282	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HLHLFFPK_01056	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLHLFFPK_01057	5.36e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HLHLFFPK_01058	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLHLFFPK_01059	1.5e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLHLFFPK_01060	6.93e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLHLFFPK_01061	1.78e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLHLFFPK_01062	1.1e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLHLFFPK_01063	1.93e-106	-	-	-	M	-	-	-	Lysin motif
HLHLFFPK_01064	3.96e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLHLFFPK_01065	4.56e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLHLFFPK_01066	2.38e-170	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLHLFFPK_01067	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
HLHLFFPK_01068	9.22e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLHLFFPK_01069	9.56e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HLHLFFPK_01070	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLHLFFPK_01071	2.8e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLHLFFPK_01072	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLHLFFPK_01073	7.45e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLHLFFPK_01074	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLHLFFPK_01075	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLHLFFPK_01076	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HLHLFFPK_01077	2.91e-184	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLHLFFPK_01078	1.96e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLHLFFPK_01079	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HLHLFFPK_01080	7.6e-306	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLHLFFPK_01081	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLHLFFPK_01082	2.03e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HLHLFFPK_01083	8.71e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HLHLFFPK_01084	1.35e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HLHLFFPK_01085	5.48e-150	-	-	-	GM	-	-	-	NmrA-like family
HLHLFFPK_01086	1.06e-314	yagE	-	-	E	-	-	-	amino acid
HLHLFFPK_01087	4.94e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLHLFFPK_01088	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_01089	7.07e-10	-	-	-	-	-	-	-	-
HLHLFFPK_01090	8.94e-161	-	-	-	S	-	-	-	Rib/alpha-like repeat
HLHLFFPK_01091	6.93e-88	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HLHLFFPK_01092	1.48e-90	-	-	-	-	-	-	-	-
HLHLFFPK_01093	2.18e-91	-	-	-	-	-	-	-	-
HLHLFFPK_01094	4.42e-105	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HLHLFFPK_01095	5.83e-172	-	-	-	-	-	-	-	-
HLHLFFPK_01097	5.88e-128	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HLHLFFPK_01098	3.14e-132	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HLHLFFPK_01099	5.79e-136	-	-	-	-	-	-	-	-
HLHLFFPK_01100	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLHLFFPK_01101	4.94e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HLHLFFPK_01102	7.73e-112	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HLHLFFPK_01103	9.73e-300	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_01104	1.34e-37	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HLHLFFPK_01105	2.84e-243	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_01106	8.33e-53	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLHLFFPK_01107	4.94e-15	-	-	-	-	-	-	-	-
HLHLFFPK_01108	3.82e-110	-	-	-	-	-	-	-	-
HLHLFFPK_01109	2.85e-166	-	-	-	-	-	-	-	-
HLHLFFPK_01111	8.48e-241	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLHLFFPK_01112	1.21e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLHLFFPK_01113	2.53e-209	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLHLFFPK_01114	2.24e-265	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLHLFFPK_01115	6.4e-281	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HLHLFFPK_01116	1.22e-06	-	-	-	-	-	-	-	-
HLHLFFPK_01119	1.8e-307	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_01120	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HLHLFFPK_01121	1.22e-269	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLHLFFPK_01122	1.3e-56	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
HLHLFFPK_01123	5.75e-127	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLHLFFPK_01124	2.79e-80	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HLHLFFPK_01125	2.78e-59	-	-	-	G	-	-	-	Protein of unknown function (DUF563)
HLHLFFPK_01126	7.92e-64	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLHLFFPK_01127	1.92e-48	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HLHLFFPK_01128	6.26e-156	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HLHLFFPK_01129	4.81e-178	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HLHLFFPK_01130	4.19e-104	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HLHLFFPK_01131	4.63e-177	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HLHLFFPK_01132	1.69e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLHLFFPK_01133	3.02e-177	epsB	-	-	M	-	-	-	biosynthesis protein
HLHLFFPK_01134	1.74e-211	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHLFFPK_01135	8.59e-103	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HLHLFFPK_01136	6.23e-209	-	-	-	-	-	-	-	-
HLHLFFPK_01137	1.39e-156	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HLHLFFPK_01138	6.95e-283	-	-	-	-	-	-	-	-
HLHLFFPK_01139	9.34e-113	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HLHLFFPK_01140	9.4e-148	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HLHLFFPK_01142	1.1e-108	-	-	-	-	-	-	-	-
HLHLFFPK_01143	6.6e-115	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHLFFPK_01144	1.26e-132	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLHLFFPK_01145	2.79e-293	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLHLFFPK_01146	2e-275	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLHLFFPK_01147	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLHLFFPK_01148	1.58e-203	-	-	-	-	-	-	-	-
HLHLFFPK_01149	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHLFFPK_01150	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLHLFFPK_01151	1.27e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLHLFFPK_01152	1.38e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLHLFFPK_01153	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLHLFFPK_01154	2.23e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HLHLFFPK_01155	8.06e-234	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLHLFFPK_01156	3.34e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLHLFFPK_01157	2.04e-123	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HLHLFFPK_01158	4e-66	ylbG	-	-	S	-	-	-	UPF0298 protein
HLHLFFPK_01159	1.36e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLHLFFPK_01160	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLHLFFPK_01161	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLHLFFPK_01162	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLHLFFPK_01163	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHLFFPK_01164	6.85e-227	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLHLFFPK_01165	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLHLFFPK_01166	3.57e-151	-	-	-	S	-	-	-	repeat protein
HLHLFFPK_01167	5.5e-162	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HLHLFFPK_01168	3.67e-277	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLHLFFPK_01169	1.27e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HLHLFFPK_01170	3.68e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLHLFFPK_01171	1.02e-164	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLHLFFPK_01172	6.32e-52	-	-	-	-	-	-	-	-
HLHLFFPK_01173	1.81e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLHLFFPK_01174	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HLHLFFPK_01175	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLHLFFPK_01176	4.46e-162	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HLHLFFPK_01177	1.39e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HLHLFFPK_01178	1.36e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HLHLFFPK_01179	9.26e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLHLFFPK_01180	6.35e-311	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLHLFFPK_01181	5.2e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLHLFFPK_01182	2.6e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLHLFFPK_01183	3.2e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLHLFFPK_01184	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLHLFFPK_01185	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLHLFFPK_01186	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLHLFFPK_01187	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HLHLFFPK_01188	1.17e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLHLFFPK_01189	1.89e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLHLFFPK_01190	2.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HLHLFFPK_01191	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HLHLFFPK_01192	3.99e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HLHLFFPK_01193	1.17e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLHLFFPK_01194	3.11e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HLHLFFPK_01195	3.73e-143	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HLHLFFPK_01196	2.31e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLHLFFPK_01197	3.31e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLHLFFPK_01198	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLHLFFPK_01199	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLHLFFPK_01200	1.91e-230	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
HLHLFFPK_01201	3.13e-159	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLHLFFPK_01202	4.43e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLHLFFPK_01203	6.1e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLHLFFPK_01204	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLHLFFPK_01206	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLHLFFPK_01207	1.06e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLHLFFPK_01208	9.21e-304	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HLHLFFPK_01209	9.34e-08	-	-	-	-	-	-	-	-
HLHLFFPK_01210	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
HLHLFFPK_01211	1.47e-315	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHLFFPK_01212	1.85e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLHLFFPK_01213	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HLHLFFPK_01214	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HLHLFFPK_01215	3.34e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HLHLFFPK_01216	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HLHLFFPK_01217	3.07e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HLHLFFPK_01218	6.02e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLHLFFPK_01219	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLHLFFPK_01220	4.95e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLHLFFPK_01221	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLHLFFPK_01222	1.13e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHLFFPK_01223	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLHLFFPK_01224	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHLFFPK_01225	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLHLFFPK_01226	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLHLFFPK_01227	8.5e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLHLFFPK_01228	5.31e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLHLFFPK_01229	4.43e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLHLFFPK_01230	8.2e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLHLFFPK_01231	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HLHLFFPK_01232	1.37e-247	ampC	-	-	V	-	-	-	Beta-lactamase
HLHLFFPK_01235	3.21e-89	-	-	-	-	-	-	-	-
HLHLFFPK_01236	1.65e-309	-	-	-	EGP	-	-	-	Major Facilitator
HLHLFFPK_01237	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLHLFFPK_01238	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
HLHLFFPK_01239	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHLFFPK_01240	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HLHLFFPK_01241	6.34e-165	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HLHLFFPK_01242	4.63e-88	-	-	-	S	-	-	-	SdpI/YhfL protein family
HLHLFFPK_01243	3.75e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLHLFFPK_01244	4.81e-77	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HLHLFFPK_01245	4.05e-53	-	-	-	S	-	-	-	Phage Mu protein F like protein
HLHLFFPK_01246	1.72e-294	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HLHLFFPK_01247	2.2e-311	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HLHLFFPK_01248	5e-84	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HLHLFFPK_01249	5.96e-37	-	-	-	-	-	-	-	-
HLHLFFPK_01253	5.12e-112	-	-	-	-	-	-	-	-
HLHLFFPK_01254	9.24e-27	-	-	-	-	-	-	-	-
HLHLFFPK_01255	7.58e-31	-	-	-	-	-	-	-	-
HLHLFFPK_01258	3.29e-54	-	-	-	-	-	-	-	-
HLHLFFPK_01259	1.59e-81	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HLHLFFPK_01265	3.43e-35	-	-	-	-	-	-	-	-
HLHLFFPK_01266	1.89e-172	-	-	-	S	-	-	-	DNA binding
HLHLFFPK_01269	1.63e-23	ansR	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_01270	5.42e-91	-	-	-	L	-	-	-	Helix-turn-helix domain
HLHLFFPK_01271	2.2e-55	-	-	-	S	-	-	-	ERF superfamily
HLHLFFPK_01273	4.47e-53	-	-	-	-	-	-	-	-
HLHLFFPK_01274	5.68e-22	-	-	-	-	-	-	-	-
HLHLFFPK_01276	1.32e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HLHLFFPK_01278	7.15e-75	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
HLHLFFPK_01279	3.2e-109	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HLHLFFPK_01280	4.4e-34	-	-	-	S	-	-	-	Bacterial PH domain
HLHLFFPK_01282	3.77e-189	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHLFFPK_01284	3.36e-289	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLHLFFPK_01285	9.87e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HLHLFFPK_01286	4.33e-109	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HLHLFFPK_01288	5.63e-77	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HLHLFFPK_01289	9.23e-55	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
HLHLFFPK_01290	2.19e-225	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HLHLFFPK_01291	5.45e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HLHLFFPK_01292	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HLHLFFPK_01293	5.31e-125	-	-	-	S	-	-	-	VanZ like family
HLHLFFPK_01294	4.49e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLHLFFPK_01295	3.6e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLHLFFPK_01296	5.08e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLHLFFPK_01297	1.25e-150	-	-	-	-	-	-	-	-
HLHLFFPK_01298	6.31e-259	-	-	-	S	-	-	-	Putative adhesin
HLHLFFPK_01299	2.48e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHLFFPK_01300	3.02e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHLFFPK_01301	2.3e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLHLFFPK_01302	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLHLFFPK_01303	4.25e-222	ybbR	-	-	S	-	-	-	YbbR-like protein
HLHLFFPK_01304	6.38e-197	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLHLFFPK_01305	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHLFFPK_01306	7.6e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_01307	1.45e-171	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHLFFPK_01308	1.46e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLHLFFPK_01309	1.07e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HLHLFFPK_01310	6.15e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLHLFFPK_01311	2.91e-109	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HLHLFFPK_01312	7.41e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HLHLFFPK_01313	1.02e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLHLFFPK_01314	8.03e-198	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HLHLFFPK_01315	2.43e-121	-	-	-	-	-	-	-	-
HLHLFFPK_01316	1.09e-110	-	-	-	-	-	-	-	-
HLHLFFPK_01317	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01318	1.13e-137	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HLHLFFPK_01319	2.95e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLHLFFPK_01320	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLHLFFPK_01321	3.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLHLFFPK_01322	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLHLFFPK_01323	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHLFFPK_01324	4.94e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLHLFFPK_01325	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLHLFFPK_01326	3.72e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HLHLFFPK_01328	0.0	ycaM	-	-	E	-	-	-	amino acid
HLHLFFPK_01329	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLHLFFPK_01330	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLHLFFPK_01331	1.54e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLHLFFPK_01332	1.58e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLHLFFPK_01333	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HLHLFFPK_01334	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLHLFFPK_01335	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLHLFFPK_01336	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLHLFFPK_01337	1.66e-206	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLHLFFPK_01338	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLHLFFPK_01339	8.11e-263	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLHLFFPK_01340	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HLHLFFPK_01341	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLHLFFPK_01342	5.52e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLHLFFPK_01343	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HLHLFFPK_01344	4.7e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HLHLFFPK_01345	1.21e-241	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLHLFFPK_01346	2.57e-19	-	-	-	L	-	-	-	Caulimovirus viroplasmin
HLHLFFPK_01348	5.2e-41	-	-	-	D	-	-	-	nuclear chromosome segregation
HLHLFFPK_01349	3.12e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLHLFFPK_01350	2.72e-238	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLHLFFPK_01351	5.09e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLHLFFPK_01352	1.67e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLHLFFPK_01353	6.45e-41	-	-	-	-	-	-	-	-
HLHLFFPK_01354	3.42e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLHLFFPK_01355	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLHLFFPK_01356	3.97e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLHLFFPK_01357	2.15e-161	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HLHLFFPK_01358	3.08e-286	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HLHLFFPK_01359	2.31e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HLHLFFPK_01360	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HLHLFFPK_01361	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLHLFFPK_01362	2.99e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLHLFFPK_01363	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLHLFFPK_01364	4.22e-178	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HLHLFFPK_01365	1.05e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLHLFFPK_01366	1.56e-294	ymfH	-	-	S	-	-	-	Peptidase M16
HLHLFFPK_01367	1.43e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HLHLFFPK_01368	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLHLFFPK_01369	6.82e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HLHLFFPK_01370	8e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLHLFFPK_01371	2.09e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HLHLFFPK_01372	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HLHLFFPK_01373	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HLHLFFPK_01374	1.23e-67	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLHLFFPK_01375	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01376	1.74e-181	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLHLFFPK_01377	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HLHLFFPK_01378	2.28e-219	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLHLFFPK_01379	3.58e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLHLFFPK_01380	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HLHLFFPK_01381	2.51e-143	-	-	-	S	-	-	-	CYTH
HLHLFFPK_01382	5.4e-140	yjbH	-	-	Q	-	-	-	Thioredoxin
HLHLFFPK_01383	6e-212	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLHLFFPK_01384	1.15e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLHLFFPK_01385	1.17e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLHLFFPK_01386	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLHLFFPK_01387	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HLHLFFPK_01388	1.02e-34	-	-	-	-	-	-	-	-
HLHLFFPK_01389	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLHLFFPK_01390	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HLHLFFPK_01391	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLHLFFPK_01392	5.48e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HLHLFFPK_01393	9.83e-101	-	-	-	-	-	-	-	-
HLHLFFPK_01394	2.36e-116	-	-	-	-	-	-	-	-
HLHLFFPK_01395	1.6e-145	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HLHLFFPK_01396	5.43e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HLHLFFPK_01397	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHLFFPK_01398	8.05e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HLHLFFPK_01399	4.19e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HLHLFFPK_01400	6.12e-278	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLHLFFPK_01401	9.41e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLHLFFPK_01403	9.84e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLHLFFPK_01404	8.36e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLHLFFPK_01405	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLHLFFPK_01406	1.32e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLHLFFPK_01407	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HLHLFFPK_01408	2.09e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HLHLFFPK_01409	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HLHLFFPK_01410	2.67e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HLHLFFPK_01411	6.82e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLHLFFPK_01412	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLHLFFPK_01413	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLHLFFPK_01414	0.0	-	-	-	S	-	-	-	membrane
HLHLFFPK_01415	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHLFFPK_01416	6.41e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLHLFFPK_01417	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHLFFPK_01418	5.46e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLHLFFPK_01419	1.19e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHLFFPK_01420	3.14e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHLFFPK_01421	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLHLFFPK_01422	9.51e-217	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHLFFPK_01423	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLHLFFPK_01424	1.89e-169	csrR	-	-	K	-	-	-	response regulator
HLHLFFPK_01425	3.13e-122	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLHLFFPK_01426	4.84e-278	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLHLFFPK_01427	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLHLFFPK_01428	1.04e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HLHLFFPK_01429	2.34e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLHLFFPK_01430	1.37e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HLHLFFPK_01431	5.48e-114	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HLHLFFPK_01432	6.48e-243	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HLHLFFPK_01433	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLHLFFPK_01434	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLHLFFPK_01435	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLHLFFPK_01436	3.73e-303	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLHLFFPK_01437	1.43e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLHLFFPK_01438	5.61e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHLFFPK_01439	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLHLFFPK_01440	1.05e-199	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLHLFFPK_01441	8.86e-303	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HLHLFFPK_01442	8.41e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLHLFFPK_01443	2.08e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLHLFFPK_01444	1.93e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLHLFFPK_01445	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLHLFFPK_01446	1.43e-80	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLHLFFPK_01447	1.12e-154	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HLHLFFPK_01448	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLHLFFPK_01449	2.29e-110	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HLHLFFPK_01450	8.43e-155	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHLFFPK_01451	1.11e-70	ytpP	-	-	CO	-	-	-	Thioredoxin
HLHLFFPK_01452	5.68e-83	-	-	-	-	-	-	-	-
HLHLFFPK_01453	9.86e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLHLFFPK_01454	7.51e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLHLFFPK_01455	1.38e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01456	9.69e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HLHLFFPK_01457	1.48e-84	-	-	-	-	-	-	-	-
HLHLFFPK_01458	8.07e-46	-	-	-	S	-	-	-	YtxH-like protein
HLHLFFPK_01459	2.5e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLHLFFPK_01460	1.25e-236	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHLFFPK_01461	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLHLFFPK_01462	2.07e-281	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HLHLFFPK_01463	1.57e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLHLFFPK_01464	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLHLFFPK_01465	3.74e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLHLFFPK_01467	0.0	-	-	-	S	-	-	-	M26 IgA1-specific Metallo-endopeptidase C-terminal region
HLHLFFPK_01468	2.79e-59	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HLHLFFPK_01469	1.82e-310	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HLHLFFPK_01470	1.7e-101	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLHLFFPK_01471	6.6e-91	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLHLFFPK_01472	8.17e-199	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HLHLFFPK_01473	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01474	2.07e-146	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HLHLFFPK_01475	2.47e-125	-	-	-	-	-	-	-	-
HLHLFFPK_01476	1.3e-201	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLHLFFPK_01477	4.02e-194	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
HLHLFFPK_01478	2.12e-253	flp	-	-	V	-	-	-	Beta-lactamase
HLHLFFPK_01480	4.19e-50	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HLHLFFPK_01481	5.03e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HLHLFFPK_01482	5.86e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HLHLFFPK_01483	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HLHLFFPK_01484	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HLHLFFPK_01485	5.12e-140	-	-	-	-	-	-	-	-
HLHLFFPK_01486	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHLFFPK_01487	2.58e-155	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLHLFFPK_01488	3.28e-166	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01489	1.56e-311	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLHLFFPK_01490	1.47e-206	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HLHLFFPK_01491	2.56e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HLHLFFPK_01492	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01493	2.1e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HLHLFFPK_01494	3.82e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLHLFFPK_01495	0.0	-	-	-	M	-	-	-	family 8
HLHLFFPK_01496	0.0	-	-	-	M	-	-	-	family 8
HLHLFFPK_01497	1.26e-289	-	-	-	M	-	-	-	Pfam:DUF1792
HLHLFFPK_01498	1.24e-99	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
HLHLFFPK_01499	0.0	-	-	-	UW	-	-	-	Tetratricopeptide repeat
HLHLFFPK_01500	3.98e-190	-	-	-	S	-	-	-	hydrolase
HLHLFFPK_01501	0.0	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHLFFPK_01502	4.51e-111	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HLHLFFPK_01503	3.61e-213	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HLHLFFPK_01504	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHLFFPK_01505	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLHLFFPK_01506	2.23e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHLFFPK_01507	1.3e-263	camS	-	-	S	-	-	-	sex pheromone
HLHLFFPK_01508	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLHLFFPK_01509	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLHLFFPK_01510	1.2e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HLHLFFPK_01511	2.91e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLHLFFPK_01513	1.07e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLHLFFPK_01514	7.76e-169	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HLHLFFPK_01515	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLHLFFPK_01516	4.92e-290	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLHLFFPK_01517	4.62e-183	-	-	-	-	-	-	-	-
HLHLFFPK_01518	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HLHLFFPK_01519	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLHLFFPK_01520	0.0	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HLHLFFPK_01521	1.58e-199	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLHLFFPK_01522	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLHLFFPK_01523	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLHLFFPK_01524	7.27e-266	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLHLFFPK_01525	6.86e-174	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLHLFFPK_01526	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HLHLFFPK_01527	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HLHLFFPK_01528	2.62e-244	-	-	-	-	-	-	-	-
HLHLFFPK_01529	1.19e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
HLHLFFPK_01532	5.98e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HLHLFFPK_01533	1.21e-45	-	-	-	K	-	-	-	SIS domain
HLHLFFPK_01534	2.51e-49	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HLHLFFPK_01536	4.88e-169	-	-	-	M	-	-	-	LysM domain protein
HLHLFFPK_01537	5.02e-166	-	-	-	M	-	-	-	LysM domain protein
HLHLFFPK_01538	5.68e-174	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HLHLFFPK_01539	4.37e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HLHLFFPK_01540	2.83e-121	-	-	-	K	-	-	-	acetyltransferase
HLHLFFPK_01542	1.53e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
HLHLFFPK_01543	2.92e-313	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HLHLFFPK_01544	5.05e-88	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HLHLFFPK_01545	1.21e-241	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLHLFFPK_01546	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HLHLFFPK_01547	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HLHLFFPK_01548	0.0	-	-	-	S	-	-	-	TerB-C domain
HLHLFFPK_01549	9.59e-49	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HLHLFFPK_01550	7.22e-105	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HLHLFFPK_01551	2.91e-94	-	-	-	-	-	-	-	-
HLHLFFPK_01552	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HLHLFFPK_01553	1.24e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLHLFFPK_01573	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHLFFPK_01574	3.15e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLHLFFPK_01575	3.5e-251	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLHLFFPK_01576	1.91e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HLHLFFPK_01588	6.09e-81	-	-	-	-	-	-	-	-
HLHLFFPK_01606	6.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLHLFFPK_01607	6.85e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLHLFFPK_01608	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLHLFFPK_01609	3.32e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLHLFFPK_01610	4.68e-198	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HLHLFFPK_01611	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLHLFFPK_01612	4.78e-226	-	-	-	-	-	-	-	-
HLHLFFPK_01613	2.6e-164	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLHLFFPK_01614	2.3e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLHLFFPK_01615	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HLHLFFPK_01616	1.8e-124	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHLFFPK_01617	4.44e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HLHLFFPK_01618	1.86e-213	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HLHLFFPK_01619	4.59e-107	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLHLFFPK_01620	3.57e-120	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLHLFFPK_01621	1.92e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
HLHLFFPK_01622	4.76e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HLHLFFPK_01623	9.33e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLHLFFPK_01624	4.66e-314	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HLHLFFPK_01625	4.82e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLHLFFPK_01626	3.57e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HLHLFFPK_01627	8.41e-260	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLHLFFPK_01628	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHLFFPK_01629	4.84e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HLHLFFPK_01630	2.52e-199	dkgB	-	-	S	-	-	-	reductase
HLHLFFPK_01631	9.66e-252	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHLFFPK_01632	1.83e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HLHLFFPK_01633	1.83e-193	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HLHLFFPK_01634	1.19e-143	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLHLFFPK_01635	1.93e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HLHLFFPK_01636	4.76e-307	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLHLFFPK_01637	2.3e-118	-	-	-	S	-	-	-	PAS domain
HLHLFFPK_01638	1.63e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HLHLFFPK_01639	0.0	-	-	-	GM	ko:K13732	ko05100,map05100	ko00000,ko00001	domain, Protein
HLHLFFPK_01640	2.42e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLHLFFPK_01641	3.65e-52	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLHLFFPK_01642	4.66e-158	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HLHLFFPK_01643	3.63e-162	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HLHLFFPK_01644	1.31e-92	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLHLFFPK_01645	3.28e-92	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HLHLFFPK_01646	4.01e-181	-	-	-	S	-	-	-	PAS domain
HLHLFFPK_01647	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01648	2.08e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLHLFFPK_01649	3.03e-257	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HLHLFFPK_01650	8.03e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLHLFFPK_01651	1.27e-81	-	-	-	-	-	-	-	-
HLHLFFPK_01652	7.71e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HLHLFFPK_01653	2.27e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HLHLFFPK_01654	7.49e-208	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLHLFFPK_01655	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLHLFFPK_01656	8.26e-197	-	-	-	EG	-	-	-	EamA-like transporter family
HLHLFFPK_01657	3.42e-88	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_01658	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HLHLFFPK_01659	5.36e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLHLFFPK_01660	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLHLFFPK_01661	2.55e-130	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLHLFFPK_01662	2.68e-154	-	-	-	S	-	-	-	Peptidase_C39 like family
HLHLFFPK_01663	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLHLFFPK_01664	4.34e-152	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHLFFPK_01666	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HLHLFFPK_01667	3.25e-185	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLHLFFPK_01668	2.31e-164	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HLHLFFPK_01669	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HLHLFFPK_01670	8.32e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLHLFFPK_01671	1.65e-69	-	-	-	-	-	-	-	-
HLHLFFPK_01672	1.32e-35	-	-	-	-	-	-	-	-
HLHLFFPK_01673	1.46e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HLHLFFPK_01674	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLHLFFPK_01675	2.68e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01676	0.0	-	-	-	E	-	-	-	Amino Acid
HLHLFFPK_01677	4.75e-157	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HLHLFFPK_01678	3.6e-159	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HLHLFFPK_01679	7.67e-176	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLHLFFPK_01680	4.53e-95	-	-	-	-	-	-	-	-
HLHLFFPK_01682	8.32e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLHLFFPK_01683	1.55e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLHLFFPK_01684	5.33e-172	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HLHLFFPK_01685	3.38e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HLHLFFPK_01686	1.87e-58	-	-	-	-	-	-	-	-
HLHLFFPK_01687	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HLHLFFPK_01688	3.86e-143	-	-	-	-	-	-	-	-
HLHLFFPK_01689	1.35e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLHLFFPK_01690	5.64e-227	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLHLFFPK_01691	3.93e-104	-	-	-	-	-	-	-	-
HLHLFFPK_01692	7.58e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLHLFFPK_01693	1.05e-53	-	-	-	-	-	-	-	-
HLHLFFPK_01694	2.22e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLHLFFPK_01695	5.17e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLHLFFPK_01696	0.0	-	-	-	S	-	-	-	ABC transporter
HLHLFFPK_01697	2.71e-81	-	-	-	-	-	-	-	-
HLHLFFPK_01698	2.47e-53	-	-	-	-	-	-	-	-
HLHLFFPK_01699	1.59e-266	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHLFFPK_01700	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HLHLFFPK_01701	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLHLFFPK_01702	1.03e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HLHLFFPK_01703	4.48e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLHLFFPK_01704	2.74e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLHLFFPK_01705	1.07e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HLHLFFPK_01706	2.58e-181	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLHLFFPK_01707	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLHLFFPK_01708	1.68e-93	-	-	-	S	-	-	-	YSIRK type signal peptide
HLHLFFPK_01709	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HLHLFFPK_01710	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLHLFFPK_01711	1.38e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HLHLFFPK_01712	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HLHLFFPK_01713	2.34e-283	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLHLFFPK_01714	1.53e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01715	1.76e-182	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLHLFFPK_01716	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLHLFFPK_01717	1.12e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HLHLFFPK_01718	2.39e-156	vanR	-	-	K	-	-	-	response regulator
HLHLFFPK_01719	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLHLFFPK_01720	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01721	3.36e-185	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HLHLFFPK_01722	1.89e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLHLFFPK_01723	1.23e-56	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HLHLFFPK_01724	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLHLFFPK_01725	1.43e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HLHLFFPK_01726	1.13e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLHLFFPK_01727	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HLHLFFPK_01728	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
HLHLFFPK_01729	9e-226	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLHLFFPK_01730	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLHLFFPK_01731	1.28e-255	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HLHLFFPK_01732	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HLHLFFPK_01733	2.22e-125	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLHLFFPK_01734	5.92e-142	-	-	-	K	-	-	-	WHG domain
HLHLFFPK_01735	5.54e-50	-	-	-	-	-	-	-	-
HLHLFFPK_01736	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHLFFPK_01737	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLHLFFPK_01738	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLHLFFPK_01739	6.94e-201	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HLHLFFPK_01740	5.63e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01741	5.03e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHLFFPK_01742	1.91e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHLFFPK_01743	4.06e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
HLHLFFPK_01744	5.95e-147	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HLHLFFPK_01745	1.14e-178	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HLHLFFPK_01746	1.29e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HLHLFFPK_01747	1.45e-52	-	-	-	-	-	-	-	-
HLHLFFPK_01748	2.6e-165	-	-	-	-	-	-	-	-
HLHLFFPK_01749	2.16e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HLHLFFPK_01750	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_01751	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HLHLFFPK_01752	2.14e-185	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HLHLFFPK_01753	2.81e-196	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLHLFFPK_01754	8.83e-201	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HLHLFFPK_01755	3.16e-93	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
HLHLFFPK_01756	4.69e-202	-	-	-	-	-	-	-	-
HLHLFFPK_01757	3.13e-99	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLHLFFPK_01758	8.68e-178	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HLHLFFPK_01759	2.06e-161	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HLHLFFPK_01760	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HLHLFFPK_01761	6.71e-113	ymdB	-	-	S	-	-	-	Macro domain protein
HLHLFFPK_01762	1.81e-46	-	-	-	-	-	-	-	-
HLHLFFPK_01763	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLHLFFPK_01764	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HLHLFFPK_01765	4.28e-177	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHLFFPK_01766	4.68e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLHLFFPK_01767	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLHLFFPK_01768	1.99e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HLHLFFPK_01769	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLHLFFPK_01770	2.61e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HLHLFFPK_01771	7.01e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HLHLFFPK_01772	1.21e-303	-	-	-	E	-	-	-	amino acid
HLHLFFPK_01773	2.51e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HLHLFFPK_01774	2.21e-296	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLHLFFPK_01775	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLHLFFPK_01776	8.6e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HLHLFFPK_01777	1.73e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HLHLFFPK_01778	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HLHLFFPK_01779	1.83e-232	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HLHLFFPK_01792	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLHLFFPK_01793	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HLHLFFPK_01794	9.68e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLHLFFPK_01795	1.23e-312	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHLFFPK_01796	2.11e-53	-	-	-	-	-	-	-	-
HLHLFFPK_01797	1.97e-275	-	-	-	E	-	-	-	Major Facilitator Superfamily
HLHLFFPK_01798	7.18e-189	pbpX2	-	-	V	-	-	-	Beta-lactamase
HLHLFFPK_01799	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLHLFFPK_01800	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHLFFPK_01801	4.7e-303	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HLHLFFPK_01802	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHLFFPK_01803	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HLHLFFPK_01804	6.13e-52	-	-	-	-	-	-	-	-
HLHLFFPK_01805	2.57e-272	-	-	-	S	-	-	-	Membrane
HLHLFFPK_01807	1.18e-78	-	-	-	-	-	-	-	-
HLHLFFPK_01808	1.88e-66	-	-	-	-	-	-	-	-
HLHLFFPK_01809	5.45e-61	-	-	-	-	-	-	-	-
HLHLFFPK_01810	1.66e-111	ykuL	-	-	S	-	-	-	(CBS) domain
HLHLFFPK_01811	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HLHLFFPK_01812	1.19e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HLHLFFPK_01813	1.81e-141	-	-	-	S	-	-	-	Putative adhesin
HLHLFFPK_01814	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HLHLFFPK_01815	2.24e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHLFFPK_01816	2.33e-47	-	-	-	-	-	-	-	-
HLHLFFPK_01817	2.07e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLHLFFPK_01818	5.84e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HLHLFFPK_01819	1.42e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HLHLFFPK_01820	2.33e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HLHLFFPK_01821	2.11e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HLHLFFPK_01824	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HLHLFFPK_01825	1.86e-124	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HLHLFFPK_01826	4.83e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLHLFFPK_01827	3.18e-261	-	-	-	S	-	-	-	DUF218 domain
HLHLFFPK_01828	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHLFFPK_01829	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HLHLFFPK_01830	1.9e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HLHLFFPK_01831	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLHLFFPK_01832	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLHLFFPK_01833	4.96e-226	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HLHLFFPK_01834	2.85e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HLHLFFPK_01835	1.83e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HLHLFFPK_01836	5.87e-195	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HLHLFFPK_01837	2.55e-247	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HLHLFFPK_01838	1.06e-203	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLHLFFPK_01839	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLHLFFPK_01840	1.8e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLHLFFPK_01841	8.84e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
HLHLFFPK_01842	5.45e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLHLFFPK_01843	8.43e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HLHLFFPK_01844	3.29e-161	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HLHLFFPK_01845	2.33e-301	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HLHLFFPK_01846	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLHLFFPK_01847	2.47e-166	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLHLFFPK_01848	5.43e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLHLFFPK_01849	1.13e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLHLFFPK_01850	4.93e-98	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HLHLFFPK_01851	4.89e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLHLFFPK_01852	4.92e-94	-	-	-	-	-	-	-	-
HLHLFFPK_01853	1.12e-117	-	-	-	-	-	-	-	-
HLHLFFPK_01854	1.61e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HLHLFFPK_01855	1.2e-83	-	-	-	S	-	-	-	Cupredoxin-like domain
HLHLFFPK_01856	7.67e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
HLHLFFPK_01857	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLHLFFPK_01858	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHLFFPK_01859	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLHLFFPK_01860	9.1e-205	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLHLFFPK_01861	0.0	-	-	-	E	-	-	-	Amino acid permease
HLHLFFPK_01862	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HLHLFFPK_01863	3.96e-314	ynbB	-	-	P	-	-	-	aluminum resistance
HLHLFFPK_01864	1.57e-85	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHLFFPK_01865	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLHLFFPK_01866	2.07e-293	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HLHLFFPK_01867	1.09e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HLHLFFPK_01868	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLHLFFPK_01869	5.8e-267	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLHLFFPK_01870	8.09e-206	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HLHLFFPK_01872	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLHLFFPK_01873	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHLFFPK_01874	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLHLFFPK_01875	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLHLFFPK_01876	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLHLFFPK_01877	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLHLFFPK_01878	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHLFFPK_01879	1.8e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLHLFFPK_01880	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family