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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDDIGPKE_00001	1.85e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDDIGPKE_00002	8.7e-157	-	-	-	S	-	-	-	peptidase M50
HDDIGPKE_00003	1.68e-135	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDDIGPKE_00004	1.14e-124	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDDIGPKE_00005	2.97e-141	-	-	-	-	-	-	-	-
HDDIGPKE_00006	2.97e-86	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HDDIGPKE_00007	3.01e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDDIGPKE_00008	1.48e-292	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDDIGPKE_00009	1.81e-166	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDDIGPKE_00010	1.16e-301	-	-	-	T	-	-	-	Histidine kinase
HDDIGPKE_00011	4.43e-100	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HDDIGPKE_00012	2.2e-224	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDDIGPKE_00013	5e-174	-	-	-	K	ko:K03710	-	ko00000,ko03000	Psort location Cytoplasmic, score
HDDIGPKE_00014	3.28e-128	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HDDIGPKE_00015	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDDIGPKE_00016	1.56e-181	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HDDIGPKE_00017	7.48e-162	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	thymidylate kinase
HDDIGPKE_00018	1.06e-189	-	-	-	-	-	-	-	-
HDDIGPKE_00019	1.51e-244	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDDIGPKE_00020	8.47e-306	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HDDIGPKE_00021	3.19e-103	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00022	3.55e-99	-	-	-	C	-	-	-	Flavodoxin
HDDIGPKE_00023	1.69e-71	-	-	-	S	-	-	-	Nitrous oxide-stimulated promoter
HDDIGPKE_00024	4.9e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HDDIGPKE_00025	3.08e-147	-	-	-	S	ko:K07025	-	ko00000	IA, variant 3
HDDIGPKE_00026	1.21e-63	-	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
HDDIGPKE_00027	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00028	5.42e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDDIGPKE_00029	1.78e-211	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDDIGPKE_00030	2e-209	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HDDIGPKE_00031	1.27e-266	-	-	-	I	-	-	-	Carboxyl transferase domain
HDDIGPKE_00032	2.2e-33	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
HDDIGPKE_00033	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
HDDIGPKE_00034	1.66e-73	-	-	-	S	-	-	-	Helix-turn-helix of DDE superfamily endonuclease
HDDIGPKE_00035	7.15e-199	yicC	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00036	5.98e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HDDIGPKE_00037	1.21e-128	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDDIGPKE_00038	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDDIGPKE_00039	6.9e-129	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDDIGPKE_00040	1.32e-217	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDDIGPKE_00041	1.69e-296	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDDIGPKE_00042	1.17e-247	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDDIGPKE_00043	3.42e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	serine threonine protein phosphatase
HDDIGPKE_00044	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDDIGPKE_00045	1.12e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDDIGPKE_00046	5.49e-149	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDDIGPKE_00047	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00048	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDDIGPKE_00049	5.44e-117	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HDDIGPKE_00051	1.78e-30	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HDDIGPKE_00053	6.85e-234	spoIIIAE	-	-	S	ko:K06394	-	ko00000	Stage III sporulation protein AE (spore_III_AE)
HDDIGPKE_00055	1.26e-62	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HDDIGPKE_00056	1.24e-118	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HDDIGPKE_00057	7.46e-74	asp	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDDIGPKE_00058	9.59e-101	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDDIGPKE_00059	2.43e-167	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDDIGPKE_00060	1.41e-209	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDIGPKE_00061	4.75e-34	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDIGPKE_00062	1.28e-197	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDDIGPKE_00063	1.39e-101	-	-	-	S	ko:K09775	-	ko00000	Divergent PAP2 family
HDDIGPKE_00064	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDDIGPKE_00065	8.86e-176	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HDDIGPKE_00066	4.34e-200	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDDIGPKE_00067	6.8e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDDIGPKE_00068	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDDIGPKE_00069	9.01e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDDIGPKE_00070	8.52e-124	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HDDIGPKE_00071	3.83e-99	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HDDIGPKE_00072	9.94e-303	capA	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
HDDIGPKE_00073	2.6e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDDIGPKE_00074	8.19e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDDIGPKE_00075	1.53e-266	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
HDDIGPKE_00076	1.37e-247	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDDIGPKE_00077	5.84e-288	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDDIGPKE_00078	5.34e-64	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
HDDIGPKE_00081	8.35e-316	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDDIGPKE_00082	9.08e-277	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HDDIGPKE_00083	1.99e-131	-	-	-	M	-	-	-	N-acetylmuramoyl-L-alanine amidase
HDDIGPKE_00084	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDDIGPKE_00085	5.22e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDDIGPKE_00086	5.42e-200	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDDIGPKE_00087	1.95e-114	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDDIGPKE_00088	1.79e-211	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HDDIGPKE_00089	6.75e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDDIGPKE_00090	1.93e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HDDIGPKE_00092	8.63e-185	-	-	-	S	ko:K07402	-	ko00000	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HDDIGPKE_00093	8.62e-232	-	-	-	O	ko:K07402	-	ko00000	XdhC and CoxI family
HDDIGPKE_00094	2.5e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
HDDIGPKE_00095	1.06e-210	csd	-	-	E	-	-	-	cysteine desulfurase family protein
HDDIGPKE_00096	2.12e-129	yedF	-	-	O	ko:K04085	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	DsrE/DsrF-like family
HDDIGPKE_00097	7.51e-239	selD	2.7.9.3	-	H	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
HDDIGPKE_00098	1.66e-154	yqeC	-	-	H	-	-	-	selenium-dependent hydroxylase accessory protein YqeC
HDDIGPKE_00099	0.0	xdhD	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00100	2.22e-112	hcrC	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	[2Fe-2S] binding domain
HDDIGPKE_00101	2.65e-177	-	-	-	C	-	-	-	FAD binding domain in molybdopterin dehydrogenase
HDDIGPKE_00102	1.04e-141	ygfJ	2.7.7.76	-	S	ko:K07141	ko00790,map00790	ko00000,ko00001,ko01000	MobA-like NTP transferase domain
HDDIGPKE_00103	8.42e-302	pbuX	-	-	F	ko:K03458	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00104	4.82e-190	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDDIGPKE_00105	3.04e-59	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDDIGPKE_00106	3.09e-151	-	-	-	E	-	-	-	AzlC protein
HDDIGPKE_00108	2.24e-19	-	-	-	-	-	-	-	-
HDDIGPKE_00109	3.03e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HDDIGPKE_00110	5.31e-33	-	-	-	-	-	-	-	-
HDDIGPKE_00111	0.000472	-	-	-	-	-	-	-	-
HDDIGPKE_00112	1.35e-50	-	-	-	-	-	-	-	-
HDDIGPKE_00113	2.65e-18	-	-	-	-	-	-	-	-
HDDIGPKE_00116	2.23e-263	-	-	-	-	-	-	-	-
HDDIGPKE_00117	1.27e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF2800)
HDDIGPKE_00118	1.19e-24	-	-	-	-	-	-	-	-
HDDIGPKE_00121	1.13e-24	-	-	-	-	-	-	-	-
HDDIGPKE_00124	1.41e-88	thyX	2.1.1.148	-	F	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HDDIGPKE_00138	8.64e-213	-	-	-	KL	-	-	-	Helicase conserved C-terminal domain
HDDIGPKE_00147	0.0	-	-	-	S	-	-	-	DNA polymerase type-B family
HDDIGPKE_00149	2.91e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HDDIGPKE_00151	1.01e-12	-	-	-	-	-	-	-	-
HDDIGPKE_00152	3.64e-69	-	-	-	-	-	-	-	-
HDDIGPKE_00153	9.99e-42	-	-	-	-	-	-	-	-
HDDIGPKE_00155	6.11e-82	-	-	-	-	-	-	-	-
HDDIGPKE_00165	2.74e-46	-	-	-	-	-	-	-	-
HDDIGPKE_00166	4.97e-06	-	-	-	-	-	-	-	-
HDDIGPKE_00171	3.84e-40	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HDDIGPKE_00172	3.04e-37	-	-	-	-	-	-	-	-
HDDIGPKE_00173	1.29e-138	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDIGPKE_00174	3.17e-11	-	-	-	I	-	-	-	Acyltransferase
HDDIGPKE_00175	5.69e-234	-	-	-	I	-	-	-	Lipid kinase, YegS Rv2252 BmrU family
HDDIGPKE_00176	0.0	clpC	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Belongs to the ClpA ClpB family
HDDIGPKE_00177	4.57e-169	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
HDDIGPKE_00178	3.29e-258	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HDDIGPKE_00179	2.03e-283	-	-	-	S	-	-	-	SPFH domain-Band 7 family
HDDIGPKE_00180	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00181	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	K transport systems, NAD-binding component
HDDIGPKE_00182	7.98e-309	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HDDIGPKE_00183	3.23e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDDIGPKE_00185	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HDDIGPKE_00186	7.27e-106	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDDIGPKE_00187	1.78e-202	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDIGPKE_00188	6.32e-228	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Psort location Cytoplasmic, score
HDDIGPKE_00190	5.84e-160	-	-	-	-	-	-	-	-
HDDIGPKE_00191	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDDIGPKE_00192	5e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDDIGPKE_00193	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDDIGPKE_00194	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDDIGPKE_00195	1.51e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HDDIGPKE_00196	4.25e-272	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDDIGPKE_00197	0.0	yybT	-	-	T	-	-	-	domain protein
HDDIGPKE_00198	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDDIGPKE_00199	1.7e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDIGPKE_00200	4.26e-115	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	sulfurtransferase activity
HDDIGPKE_00201	4.06e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HDDIGPKE_00202	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HDDIGPKE_00203	6.63e-122	-	-	-	S	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HDDIGPKE_00204	4.03e-162	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDDIGPKE_00205	1.63e-235	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HDDIGPKE_00206	3.01e-131	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HDDIGPKE_00207	6.48e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HDDIGPKE_00208	0.0	ydcP	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HDDIGPKE_00209	6.82e-65	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDDIGPKE_00210	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDDIGPKE_00211	0.0	apu	2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54	GH13,GH31,GH77	G	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDDIGPKE_00212	1.63e-99	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00213	1.05e-154	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HDDIGPKE_00215	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDDIGPKE_00216	0.0	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HDDIGPKE_00217	1.03e-22	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDDIGPKE_00218	1.42e-288	spoIVB	3.4.21.116	-	S	ko:K06399	-	ko00000,ko01000,ko01002	stage IV sporulation protein B
HDDIGPKE_00219	1.68e-177	spo0A	-	-	K	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HDDIGPKE_00220	7.66e-163	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00221	1.33e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDDIGPKE_00222	1.04e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDDIGPKE_00223	1.29e-169	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDDIGPKE_00224	1.96e-193	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00225	1.81e-272	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HDDIGPKE_00226	5.81e-251	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
HDDIGPKE_00227	1.49e-251	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HDDIGPKE_00228	0.0	polC	2.7.7.7	-	L	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDIGPKE_00229	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HDDIGPKE_00230	4.34e-75	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDDIGPKE_00231	3.88e-106	-	-	-	S	-	-	-	CBS domain
HDDIGPKE_00232	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HDDIGPKE_00233	3.46e-205	nfnA	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	domain protein
HDDIGPKE_00239	6.44e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDDIGPKE_00240	9.05e-232	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00241	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDDIGPKE_00242	9.51e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HDDIGPKE_00243	1.8e-59	-	-	-	C	-	-	-	decarboxylase gamma
HDDIGPKE_00244	2.04e-274	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	decarboxylase beta subunit
HDDIGPKE_00245	5.44e-163	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HDDIGPKE_00246	1.69e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDIGPKE_00247	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00248	7.41e-65	-	-	-	S	-	-	-	protein, YerC YecD
HDDIGPKE_00249	2.71e-72	-	-	-	-	-	-	-	-
HDDIGPKE_00250	8.39e-129	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00251	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDDIGPKE_00253	6.59e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00254	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HDDIGPKE_00255	2.77e-116	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Psort location CytoplasmicMembrane, score
HDDIGPKE_00256	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HDDIGPKE_00257	5.75e-141	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDDIGPKE_00258	1.69e-180	-	-	-	Q	-	-	-	Methyltransferase domain protein
HDDIGPKE_00259	1.48e-196	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDDIGPKE_00260	2.49e-256	yqfD	-	-	M	ko:K06438	-	ko00000	Putative stage IV sporulation protein YqfD
HDDIGPKE_00262	3.19e-245	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HDDIGPKE_00264	5.21e-71	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HDDIGPKE_00266	1.18e-196	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDIGPKE_00267	2.7e-173	-	-	-	S	ko:K06940	-	ko00000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00268	7.5e-208	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HDDIGPKE_00269	5.46e-193	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
HDDIGPKE_00270	7.62e-178	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00271	2.05e-117	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HDDIGPKE_00272	1.04e-274	-	2.7.1.45	-	H	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HDDIGPKE_00273	1.74e-221	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	pyruvate formate lyase activating
HDDIGPKE_00274	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HDDIGPKE_00275	9.62e-289	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDDIGPKE_00276	2.82e-190	yycJ	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HDDIGPKE_00277	5.79e-222	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
HDDIGPKE_00278	2.97e-213	dnaD	-	-	-	ko:K02086	-	ko00000	-
HDDIGPKE_00279	1.86e-90	-	-	-	-	-	-	-	-
HDDIGPKE_00281	9.71e-56	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDDIGPKE_00282	2.5e-172	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDDIGPKE_00283	2.9e-107	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
HDDIGPKE_00284	7.19e-183	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein, CT1132 family
HDDIGPKE_00285	1.22e-283	csd1	-	-	S	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
HDDIGPKE_00286	2.09e-125	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HDDIGPKE_00287	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase, Cas3
HDDIGPKE_00288	5.7e-33	-	-	-	S	-	-	-	Transglycosylase associated protein
HDDIGPKE_00289	6.13e-164	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDDIGPKE_00290	2.87e-308	yrvN	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
HDDIGPKE_00291	4.75e-92	-	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDDIGPKE_00292	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HDDIGPKE_00293	1.79e-92	-	-	-	S	-	-	-	Belongs to the UPF0342 family
HDDIGPKE_00294	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDDIGPKE_00295	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDDIGPKE_00296	2.33e-177	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDDIGPKE_00297	4.41e-305	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDDIGPKE_00298	3.29e-104	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDDIGPKE_00299	1.4e-195	-	-	-	S	-	-	-	S4 domain protein
HDDIGPKE_00300	2.94e-120	-	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HDDIGPKE_00301	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDDIGPKE_00302	2.26e-233	-	-	-	-	-	-	-	-
HDDIGPKE_00303	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HDDIGPKE_00304	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00305	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDDIGPKE_00306	1.23e-111	-	-	-	K	-	-	-	MarR family
HDDIGPKE_00307	6.78e-216	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDDIGPKE_00308	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDDIGPKE_00309	6.61e-231	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HDDIGPKE_00310	1.02e-108	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDDIGPKE_00311	1.15e-301	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDDIGPKE_00312	1.8e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDDIGPKE_00313	1.26e-217	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HDDIGPKE_00314	3.65e-251	-	-	-	S	-	-	-	Nitronate monooxygenase
HDDIGPKE_00315	2.95e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
HDDIGPKE_00316	1.85e-213	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDDIGPKE_00317	5.43e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDDIGPKE_00318	2.73e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDDIGPKE_00319	2.87e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDIGPKE_00320	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDDIGPKE_00321	9.37e-309	-	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HDDIGPKE_00322	5.51e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDDIGPKE_00323	3.78e-290	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00324	1.48e-100	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDDIGPKE_00325	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDDIGPKE_00326	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HDDIGPKE_00327	9.3e-102	-	-	-	-	-	-	-	-
HDDIGPKE_00328	3.28e-230	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDDIGPKE_00329	4.12e-47	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDDIGPKE_00330	1.11e-60	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00331	3.73e-144	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HDDIGPKE_00332	1.37e-217	-	-	-	G	-	-	-	Aldose 1-epimerase
HDDIGPKE_00333	2.39e-256	-	-	-	T	-	-	-	Histidine kinase
HDDIGPKE_00334	1.4e-153	-	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDDIGPKE_00335	3.46e-25	-	-	-	-	-	-	-	-
HDDIGPKE_00336	1.66e-194	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00337	3.05e-184	-	-	-	CO	ko:K06196	-	ko00000,ko02000	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDDIGPKE_00338	0.0	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HDDIGPKE_00339	1.51e-169	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HDDIGPKE_00340	6.8e-115	-	-	-	C	-	-	-	Flavodoxin domain
HDDIGPKE_00341	3.39e-227	-	1.1.1.29, 1.1.1.399, 1.1.1.95	-	CH	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HDDIGPKE_00343	1.24e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDDIGPKE_00344	2.73e-86	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDDIGPKE_00345	3.46e-205	-	-	-	T	-	-	-	cheY-homologous receiver domain
HDDIGPKE_00346	8.84e-43	-	-	-	S	-	-	-	Protein conserved in bacteria
HDDIGPKE_00347	1.19e-235	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HDDIGPKE_00348	2.69e-277	-	2.7.1.165	-	G	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	MOFRL family
HDDIGPKE_00349	5.59e-293	-	-	-	M	-	-	-	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDDIGPKE_00351	3.77e-63	-	-	-	S	-	-	-	No similarity found
HDDIGPKE_00352	6.39e-29	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HDDIGPKE_00353	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00357	2.37e-21	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDIGPKE_00359	7.44e-187	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HDDIGPKE_00360	0.0	-	-	-	F	-	-	-	S-layer homology domain
HDDIGPKE_00361	3.34e-269	macB1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HDDIGPKE_00362	1.5e-174	macB	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDDIGPKE_00363	0.0	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HDDIGPKE_00364	7.61e-93	-	-	-	S	-	-	-	NusG domain II
HDDIGPKE_00365	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDDIGPKE_00366	2.1e-107	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00367	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDDIGPKE_00368	4.09e-218	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDDIGPKE_00369	5.18e-251	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate-ammonia ligase
HDDIGPKE_00371	4.18e-18	-	-	-	K	-	-	-	transcriptional
HDDIGPKE_00372	5.4e-162	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDIGPKE_00373	5.28e-199	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems ATPase component
HDDIGPKE_00374	9.65e-213	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDIGPKE_00375	3.12e-193	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDIGPKE_00376	2.36e-239	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems periplasmic component
HDDIGPKE_00377	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00378	3.46e-302	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDDIGPKE_00380	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HDDIGPKE_00381	6.46e-136	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDDIGPKE_00382	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HDDIGPKE_00383	1.25e-169	spoVFA	-	-	EH	ko:K06410	-	ko00000	dipicolinic acid synthetase, A subunit
HDDIGPKE_00384	1.58e-132	spoVFB	-	-	H	ko:K06411	-	ko00000	Dipicolinic acid synthetase, B subunit
HDDIGPKE_00385	6.58e-310	dacB_3	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDIGPKE_00386	5.62e-142	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDDIGPKE_00387	1.97e-186	pyrL	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HDDIGPKE_00388	5.44e-176	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00389	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HDDIGPKE_00390	4.68e-136	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00395	9.26e-309	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_00396	2.18e-218	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_00397	1.54e-119	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_00398	2.29e-248	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDDIGPKE_00399	0.0	ymfH	-	-	S	-	-	-	Peptidase M16 inactive domain
HDDIGPKE_00400	4.26e-268	-	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HDDIGPKE_00401	1.67e-183	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	serine-type D-Ala-D-Ala carboxypeptidase
HDDIGPKE_00402	3.4e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDDIGPKE_00403	3.74e-210	thrB	2.7.1.39	-	H	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDDIGPKE_00404	5.43e-295	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDDIGPKE_00405	9.51e-88	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HDDIGPKE_00406	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDDIGPKE_00408	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HDDIGPKE_00410	7.71e-148	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HDDIGPKE_00411	5.95e-218	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
HDDIGPKE_00412	6.88e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDDIGPKE_00413	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HDDIGPKE_00414	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HDDIGPKE_00415	2.85e-213	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00416	0.0	-	-	-	C	-	-	-	domain protein
HDDIGPKE_00417	1.47e-214	-	-	-	S	-	-	-	ATPase family associated with various cellular activities (AAA)
HDDIGPKE_00418	0.0	-	-	-	P	-	-	-	von Willebrand factor (vWF) type A domain
HDDIGPKE_00420	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type oligopeptide transport system periplasmic component
HDDIGPKE_00421	2.35e-244	appF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDIGPKE_00422	2.57e-67	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_00423	3.97e-137	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_00424	6.23e-192	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
HDDIGPKE_00425	2.22e-184	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDDIGPKE_00426	8.11e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDDIGPKE_00427	2.61e-117	-	-	-	-	-	-	-	-
HDDIGPKE_00428	1.22e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00429	8.51e-187	-	-	-	S	-	-	-	Psort location
HDDIGPKE_00432	0.0	pz-A	-	-	E	-	-	-	Peptidase family M3
HDDIGPKE_00433	2.12e-101	-	-	-	S	-	-	-	Pfam:DUF3816
HDDIGPKE_00434	1.57e-298	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDDIGPKE_00435	6.48e-100	-	-	-	-	-	-	-	-
HDDIGPKE_00437	2.18e-216	-	-	-	GK	-	-	-	ROK family
HDDIGPKE_00438	5.88e-267	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDIGPKE_00439	9.64e-251	-	-	-	T	-	-	-	diguanylate cyclase
HDDIGPKE_00440	1.07e-47	-	-	-	-	-	-	-	-
HDDIGPKE_00441	6.87e-120	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDDIGPKE_00442	3.27e-229	scrK	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00443	3.02e-294	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00444	2.94e-165	-	-	-	K	-	-	-	transcriptional regulator AraC family
HDDIGPKE_00445	9.24e-269	-	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDIGPKE_00446	3.17e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HDDIGPKE_00447	2.14e-170	tsaA	-	-	S	-	-	-	Methyltransferase, YaeB family
HDDIGPKE_00448	2.48e-25	-	-	-	-	-	-	-	-
HDDIGPKE_00449	2.53e-147	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Psort location Cytoplasmic, score
HDDIGPKE_00452	2.3e-69	-	-	-	Q	-	-	-	Methyltransferase domain
HDDIGPKE_00453	0.000669	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDDIGPKE_00454	6.85e-21	-	-	-	-	-	-	-	-
HDDIGPKE_00455	2.36e-40	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDDIGPKE_00458	2.4e-208	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00459	3.83e-127	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDDIGPKE_00460	1.06e-143	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDDIGPKE_00461	0.0	cls1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDDIGPKE_00462	9.05e-218	-	-	-	-	-	-	-	-
HDDIGPKE_00463	1.3e-165	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDDIGPKE_00464	8.74e-141	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HDDIGPKE_00465	6.12e-184	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDDIGPKE_00466	1.19e-315	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_00467	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HDDIGPKE_00468	4.23e-213	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
HDDIGPKE_00469	5.26e-58	-	-	-	S	-	-	-	TSCPD domain
HDDIGPKE_00470	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HDDIGPKE_00471	0.0	ushA	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDDIGPKE_00474	3.59e-21	scfA	-	-	S	-	-	-	RSAM-modified six-cysteine peptide
HDDIGPKE_00475	0.0	scfB	-	-	C	ko:K06871	-	ko00000	Radical SAM
HDDIGPKE_00476	0.0	-	4.1.1.18, 4.1.1.19	-	E	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HDDIGPKE_00477	3.93e-140	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HDDIGPKE_00478	6.56e-182	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDDIGPKE_00479	8.13e-208	-	-	-	C	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase catalytic
HDDIGPKE_00480	1.13e-182	-	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	homoserine dehydrogenase
HDDIGPKE_00481	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDDIGPKE_00482	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDDIGPKE_00484	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HDDIGPKE_00485	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDDIGPKE_00486	2.63e-156	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00487	1.83e-88	-	-	-	S	-	-	-	YjbR
HDDIGPKE_00488	7.46e-233	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDDIGPKE_00489	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HDDIGPKE_00490	8.52e-216	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDDIGPKE_00491	7.58e-187	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDDIGPKE_00492	2.43e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HDDIGPKE_00493	3.35e-218	hprK	-	-	H	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDDIGPKE_00494	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HDDIGPKE_00495	9.72e-156	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
HDDIGPKE_00496	1.28e-310	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDDIGPKE_00499	0.0	-	-	-	EG	ko:K06295	-	ko00000	spore germination protein
HDDIGPKE_00500	4.74e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDDIGPKE_00502	1.83e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDDIGPKE_00503	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HDDIGPKE_00504	0.0	-	-	-	EK	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDDIGPKE_00505	1.98e-314	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDDIGPKE_00506	3.34e-139	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDDIGPKE_00507	3.96e-82	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDIGPKE_00508	3.45e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00509	1.19e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDDIGPKE_00510	5.61e-113	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDDIGPKE_00511	4.2e-268	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HDDIGPKE_00512	0.0	agcS_2	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HDDIGPKE_00513	2.13e-295	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00514	1.28e-130	yfcE	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDDIGPKE_00515	6.96e-214	-	2.7.1.40	-	H	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HDDIGPKE_00516	4.05e-214	-	2.7.1.15, 2.7.1.83	-	H	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00517	7.43e-257	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00519	2.25e-182	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDIGPKE_00520	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HDDIGPKE_00521	4.33e-184	aroD	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HDDIGPKE_00522	0.0	-	-	-	C	-	-	-	NADH oxidase
HDDIGPKE_00523	1.77e-185	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HDDIGPKE_00524	1.9e-314	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00525	5.59e-271	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00527	4.44e-293	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HDDIGPKE_00528	9.81e-106	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDDIGPKE_00529	3.16e-197	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HDDIGPKE_00531	1.75e-94	-	-	-	-	-	-	-	-
HDDIGPKE_00532	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDDIGPKE_00533	6.23e-305	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDDIGPKE_00534	7.69e-115	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDDIGPKE_00535	6.69e-264	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDDIGPKE_00536	7.05e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC-type polar amino acid transport system ATPase component
HDDIGPKE_00537	4.56e-167	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	acid ABC transporter
HDDIGPKE_00538	7.13e-160	artP	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDDIGPKE_00539	1.94e-130	-	-	-	C	-	-	-	Nitroreductase family
HDDIGPKE_00540	3.71e-90	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDDIGPKE_00541	1.95e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDDIGPKE_00542	2.62e-191	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HDDIGPKE_00543	1.21e-208	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDDIGPKE_00544	2.37e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type metal ion transport system permease component
HDDIGPKE_00545	1.96e-315	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
HDDIGPKE_00546	7.76e-233	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDDIGPKE_00547	5.78e-213	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDDIGPKE_00548	1.26e-126	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDDIGPKE_00549	1.06e-161	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
HDDIGPKE_00552	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HDDIGPKE_00553	5.79e-316	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
HDDIGPKE_00555	2.85e-285	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDIGPKE_00556	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDDIGPKE_00557	0.0	cydD	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00558	0.0	cydC	-	-	V	ko:K06148	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00559	8.93e-226	envE	3.1.4.46, 3.2.1.18, 3.2.1.8	GH33	E	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	ko00000,ko00001,ko01000,ko02042	lipolytic protein G-D-S-L family
HDDIGPKE_00560	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HDDIGPKE_00561	7.12e-279	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HDDIGPKE_00562	9.82e-213	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDIGPKE_00563	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00564	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDDIGPKE_00565	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
HDDIGPKE_00566	2.83e-116	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
HDDIGPKE_00567	6.4e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00568	3.49e-191	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDIGPKE_00569	0.0	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
HDDIGPKE_00570	3.66e-221	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00571	5.32e-265	-	-	-	S	-	-	-	domain protein
HDDIGPKE_00572	6.74e-244	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDDIGPKE_00573	6.28e-249	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HDDIGPKE_00574	1e-153	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HDDIGPKE_00575	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
HDDIGPKE_00576	5.99e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDDIGPKE_00577	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00578	8.68e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HDDIGPKE_00579	8.08e-265	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00580	1.95e-172	-	-	-	HP	-	-	-	small periplasmic lipoprotein
HDDIGPKE_00581	1.06e-258	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HDDIGPKE_00582	2.83e-219	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDDIGPKE_00583	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HDDIGPKE_00584	1.49e-171	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C11-methyltransferase
HDDIGPKE_00585	2.32e-215	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HDDIGPKE_00586	5.66e-182	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-3B
HDDIGPKE_00587	2.86e-161	cobK	1.3.1.106, 1.3.1.54, 1.3.1.76, 4.99.1.4	-	H	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	reductase
HDDIGPKE_00588	4.99e-273	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
HDDIGPKE_00589	1.38e-308	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HDDIGPKE_00590	1.97e-234	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HDDIGPKE_00591	1.69e-113	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase
HDDIGPKE_00592	2.79e-175	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HDDIGPKE_00593	3.7e-70	-	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HDDIGPKE_00594	1.53e-140	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00595	8.55e-219	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HDDIGPKE_00596	4.16e-236	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00597	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HDDIGPKE_00598	4.26e-148	cobH	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00599	1.23e-73	-	-	-	L	-	-	-	DNA modification repair radical SAM protein
HDDIGPKE_00600	5.96e-198	-	-	-	L	-	-	-	DNA metabolism protein
HDDIGPKE_00601	2.13e-57	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HDDIGPKE_00602	9.38e-115	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDDIGPKE_00603	0.0	-	-	-	S	ko:K07137	-	ko00000	Oxidoreductase
HDDIGPKE_00604	2.73e-149	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HDDIGPKE_00605	3.56e-287	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00606	1.93e-139	-	-	-	F	-	-	-	Cytidylate kinase-like family
HDDIGPKE_00607	0.0	-	-	-	-	-	-	-	-
HDDIGPKE_00608	2.93e-196	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00609	1.49e-166	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HDDIGPKE_00610	3.16e-181	-	-	-	-	-	-	-	-
HDDIGPKE_00612	2.85e-244	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HDDIGPKE_00613	5.15e-247	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDDIGPKE_00614	3.45e-264	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDDIGPKE_00615	9.41e-296	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDDIGPKE_00616	6.66e-113	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HDDIGPKE_00617	5.77e-244	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HDDIGPKE_00618	2.06e-295	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDDIGPKE_00619	2e-207	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDDIGPKE_00620	2.13e-229	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00621	0.0	-	-	-	O	-	-	-	ATPase, AAA family
HDDIGPKE_00622	7.95e-56	-	-	-	-	-	-	-	-
HDDIGPKE_00623	2.94e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00624	6.52e-155	cobW	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
HDDIGPKE_00625	6.86e-189	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDDIGPKE_00626	2.39e-226	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HDDIGPKE_00627	8.39e-196	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDIGPKE_00628	1.31e-216	cbiO	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDIGPKE_00629	3.51e-184	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDIGPKE_00630	5.03e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDDIGPKE_00631	5.25e-279	-	-	-	-	-	-	-	-
HDDIGPKE_00632	9.86e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00633	0.0	-	-	-	O	ko:K03697	-	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HDDIGPKE_00634	7.68e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDDIGPKE_00635	3.22e-103	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00636	0.0	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDDIGPKE_00637	5.13e-64	-	-	-	-	-	-	-	-
HDDIGPKE_00638	1.06e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HDDIGPKE_00639	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HDDIGPKE_00640	6.42e-237	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HDDIGPKE_00642	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HDDIGPKE_00643	6.63e-163	resD	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HDDIGPKE_00644	1.94e-316	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HDDIGPKE_00645	1.92e-299	-	3.1.1.17	-	G	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	gluconolactonase activity
HDDIGPKE_00646	5.39e-130	-	-	-	S	-	-	-	Belongs to the UPF0340 family
HDDIGPKE_00647	2.56e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDDIGPKE_00648	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HDDIGPKE_00649	3.75e-147	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HDDIGPKE_00650	9.04e-297	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_00651	4.48e-99	-	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
HDDIGPKE_00654	5.02e-117	yvdD	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HDDIGPKE_00655	4.37e-122	chrA2	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HDDIGPKE_00656	7.18e-114	chrA1	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HDDIGPKE_00657	9.41e-176	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HDDIGPKE_00658	1.34e-297	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDIGPKE_00659	8.57e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00660	3.93e-181	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HDDIGPKE_00661	8.61e-251	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDDIGPKE_00662	2.39e-209	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HDDIGPKE_00663	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	transport system
HDDIGPKE_00664	1.65e-187	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00665	8.91e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HDDIGPKE_00666	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HDDIGPKE_00668	4.78e-46	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HDDIGPKE_00670	1.32e-17	-	-	-	-	-	-	-	-
HDDIGPKE_00674	1.34e-08	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HDDIGPKE_00676	1.57e-198	-	-	-	IQ	-	-	-	short chain dehydrogenase
HDDIGPKE_00677	3.15e-206	-	-	-	M	-	-	-	Domain of unknown function (DUF4349)
HDDIGPKE_00678	1.04e-114	-	-	-	K	ko:K03088	-	ko00000,ko03021	Putative ATPase subunit of terminase (gpP-like)
HDDIGPKE_00681	2.09e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDDIGPKE_00682	2.74e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDDIGPKE_00683	1.28e-117	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HDDIGPKE_00684	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
HDDIGPKE_00685	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	asparagine synthase (glutamine-hydrolyzing)
HDDIGPKE_00686	1.74e-116	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDDIGPKE_00687	4.48e-152	-	-	-	K	-	-	-	FCD
HDDIGPKE_00688	3.12e-183	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00689	1.05e-202	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
HDDIGPKE_00690	4.34e-228	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HDDIGPKE_00691	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00692	1.41e-134	yfbR	3.1.3.89	-	S	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	PFAM metal-dependent phosphohydrolase HD sub domain
HDDIGPKE_00693	2.76e-247	dus	-	-	H	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDIGPKE_00694	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDDIGPKE_00695	6.28e-104	-	-	-	S	ko:K02441	-	ko00000	Rhomboid family
HDDIGPKE_00696	1.27e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00697	1.02e-298	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HDDIGPKE_00698	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDDIGPKE_00699	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDDIGPKE_00700	1.11e-125	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
HDDIGPKE_00701	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDDIGPKE_00702	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HDDIGPKE_00705	2.53e-183	-	-	-	G	-	-	-	polysaccharide deacetylase
HDDIGPKE_00706	3.56e-198	hmrR	-	-	K	-	-	-	Transcriptional regulator
HDDIGPKE_00707	0.0	apeA	-	-	E	-	-	-	M18 family aminopeptidase
HDDIGPKE_00708	2.14e-103	-	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HDDIGPKE_00709	4.82e-131	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDDIGPKE_00710	2.18e-245	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDDIGPKE_00711	1.67e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDDIGPKE_00712	4.7e-39	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00713	3e-223	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
HDDIGPKE_00714	2.29e-125	-	-	-	K	-	-	-	Domain of unknown function (DUF4364)
HDDIGPKE_00715	1.88e-311	spoIVA	-	-	P	ko:K06398	-	ko00000	Stage IV sporulation protein A (spore_IV_A)
HDDIGPKE_00716	7.06e-238	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDDIGPKE_00717	1.39e-35	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDDIGPKE_00718	1.55e-229	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HDDIGPKE_00719	1.22e-288	-	-	-	-	-	-	-	-
HDDIGPKE_00720	0.0	-	-	-	M	-	-	-	Diguanylate cyclase, GGDEF domain
HDDIGPKE_00721	7.6e-289	-	-	-	V	-	-	-	Glycosyl transferase, family 2
HDDIGPKE_00722	9.62e-95	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HDDIGPKE_00723	6.24e-10	-	-	-	G	-	-	-	Acyltransferase family
HDDIGPKE_00724	2.21e-216	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase group 2 family protein
HDDIGPKE_00725	3.6e-62	-	-	-	M	-	-	-	CDP-glycerol poly(glycerophosphate) glycerophosphotransferase
HDDIGPKE_00726	1.42e-70	-	-	-	K	-	-	-	Probable zinc-ribbon domain
HDDIGPKE_00727	1.04e-290	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDIGPKE_00728	1.31e-269	-	-	-	S	-	-	-	Belongs to the UPF0348 family
HDDIGPKE_00729	0.0	-	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HDDIGPKE_00730	1.11e-68	-	-	-	T	-	-	-	GHKL domain
HDDIGPKE_00731	7.8e-103	-	-	-	KT	-	-	-	response regulator
HDDIGPKE_00732	0.0	glpK	2.7.1.30	-	H	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDDIGPKE_00733	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00734	8.74e-236	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	PFAM Phosphate acetyl butaryl transferase
HDDIGPKE_00735	1.37e-134	udgA	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HDDIGPKE_00736	6.62e-257	-	-	-	LO	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00737	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	HELICc2
HDDIGPKE_00738	1.25e-114	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cob(I)yrinic acid a,c-diamide adenosyltransferase
HDDIGPKE_00739	1.03e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDDIGPKE_00740	6.94e-119	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDDIGPKE_00741	5.72e-126	fchA	-	-	E	-	-	-	Formiminotransferase-cyclodeaminase
HDDIGPKE_00742	9.07e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDDIGPKE_00743	5.57e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Glycosyl transferase family 4
HDDIGPKE_00744	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_00745	9.13e-133	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDDIGPKE_00746	2.52e-241	-	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HDDIGPKE_00747	4.33e-261	-	-	-	G	-	-	-	Major Facilitator
HDDIGPKE_00748	0.0	-	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase class C
HDDIGPKE_00749	2.52e-85	-	-	-	S	-	-	-	Bacterial PH domain
HDDIGPKE_00752	0.0	-	-	-	J	ko:K07576	-	ko00000	Metallo-beta-lactamase domain protein
HDDIGPKE_00753	1.12e-39	-	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDDIGPKE_00755	4.13e-216	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00757	3.41e-193	-	-	-	J	-	-	-	SpoU rRNA Methylase family
HDDIGPKE_00758	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00761	1.03e-09	-	-	-	T	-	-	-	Histidine kinase
HDDIGPKE_00762	2.21e-194	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDDIGPKE_00763	5.49e-191	-	-	-	S	-	-	-	HAD hydrolase, family IIB
HDDIGPKE_00764	2.52e-85	-	-	-	S	-	-	-	YjbR
HDDIGPKE_00765	4.71e-74	-	-	-	-	-	-	-	-
HDDIGPKE_00766	8.08e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
HDDIGPKE_00767	1.29e-110	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDDIGPKE_00768	7.1e-152	-	-	-	K	-	-	-	FCD
HDDIGPKE_00769	0.0	NPD5_3681	-	-	E	-	-	-	amino acid
HDDIGPKE_00770	0.0	apeB	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
HDDIGPKE_00771	5.44e-104	-	-	-	F	-	-	-	Belongs to the 5'-nucleotidase family
HDDIGPKE_00772	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HDDIGPKE_00773	1.42e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00774	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HDDIGPKE_00775	1.08e-111	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
HDDIGPKE_00776	9.06e-185	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDIGPKE_00777	2.21e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00778	2.72e-124	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDIGPKE_00779	1.41e-125	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family
HDDIGPKE_00780	1.91e-262	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDDIGPKE_00781	4.33e-225	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HDDIGPKE_00782	1.42e-266	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HDDIGPKE_00783	2.32e-280	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00785	5.97e-282	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HDDIGPKE_00786	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDDIGPKE_00787	2.99e-130	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDDIGPKE_00788	1.55e-311	ynbB	-	-	P	-	-	-	Cystathionine beta-lyase family protein involved in aluminum resistance
HDDIGPKE_00789	1.37e-99	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HDDIGPKE_00790	3.71e-215	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDDIGPKE_00792	9.48e-157	-	-	-	S	-	-	-	HAD-hyrolase-like
HDDIGPKE_00793	3.14e-110	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00794	7.91e-141	-	-	-	S	-	-	-	Flavin reductase-like protein
HDDIGPKE_00795	5.26e-234	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HDDIGPKE_00796	3.64e-150	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HDDIGPKE_00797	2.07e-223	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	Menaquinone biosynthesis
HDDIGPKE_00798	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDDIGPKE_00799	8.53e-166	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	COG COG1349 Transcriptional regulators of sugar metabolism
HDDIGPKE_00800	1.9e-203	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDDIGPKE_00801	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HDDIGPKE_00802	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00803	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDDIGPKE_00804	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDDIGPKE_00805	1.33e-176	fdhD	-	-	C	ko:K02379	-	ko00000	FdhD/NarQ family
HDDIGPKE_00807	4.48e-145	-	-	-	C	-	-	-	4Fe-4S binding domain
HDDIGPKE_00808	1.33e-60	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDDIGPKE_00809	1.55e-137	-	-	-	S	-	-	-	domain, Protein
HDDIGPKE_00810	8.27e-188	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HDDIGPKE_00811	7.02e-62	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
HDDIGPKE_00812	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDDIGPKE_00813	1.53e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HDDIGPKE_00814	4.76e-70	-	-	-	-	-	-	-	-
HDDIGPKE_00816	1.18e-46	-	-	-	S	-	-	-	Putative cell wall binding repeat
HDDIGPKE_00818	1.97e-162	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00819	3.86e-194	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HDDIGPKE_00820	5e-224	-	-	-	K	-	-	-	AraC-like ligand binding domain
HDDIGPKE_00822	3.84e-145	-	-	-	-	-	-	-	-
HDDIGPKE_00824	2.2e-180	-	-	-	S	-	-	-	TraX protein
HDDIGPKE_00826	1.65e-127	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDDIGPKE_00827	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDDIGPKE_00828	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HDDIGPKE_00829	3.01e-97	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDDIGPKE_00830	2.58e-166	-	5.2.1.8	-	M	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDDIGPKE_00831	1.43e-63	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00832	6.96e-158	-	-	-	-	-	-	-	-
HDDIGPKE_00833	7.8e-31	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HDDIGPKE_00834	6.13e-201	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDDIGPKE_00835	2.18e-290	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HDDIGPKE_00836	2.04e-105	Lrp	-	-	K	-	-	-	Transcriptional regulator, AsnC family
HDDIGPKE_00837	4.12e-56	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HDDIGPKE_00838	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HDDIGPKE_00839	9.01e-139	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HDDIGPKE_00840	3.04e-110	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
HDDIGPKE_00841	6.19e-228	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDDIGPKE_00842	5.34e-185	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDDIGPKE_00843	1.09e-271	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HDDIGPKE_00844	1.11e-206	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDDIGPKE_00845	1.58e-301	-	-	-	S	-	-	-	YbbR-like protein
HDDIGPKE_00846	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD dependent oxidoreductase
HDDIGPKE_00847	2.92e-255	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HDDIGPKE_00848	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	exonuclease
HDDIGPKE_00849	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDDIGPKE_00850	3.18e-106	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDDIGPKE_00851	6.71e-147	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HDDIGPKE_00852	0.0	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
HDDIGPKE_00853	7.67e-224	-	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase uridine kinase family
HDDIGPKE_00854	6.17e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00855	2.03e-121	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
HDDIGPKE_00856	7.71e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDIGPKE_00857	3.33e-47	hslR	-	-	J	-	-	-	S4 domain protein
HDDIGPKE_00858	2.86e-09	yabP	-	-	S	-	-	-	Sporulation protein YabP
HDDIGPKE_00859	2.9e-79	-	-	-	-	-	-	-	-
HDDIGPKE_00860	4.49e-61	-	-	-	D	ko:K13052	-	ko00000,ko03036	septum formation initiator
HDDIGPKE_00861	8.02e-84	-	3.1.2.29	-	S	ko:K18700	-	ko00000,ko01000	thioesterase
HDDIGPKE_00863	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00864	6.2e-103	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDDIGPKE_00865	1.07e-85	-	-	-	S	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
HDDIGPKE_00866	0.0	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDDIGPKE_00867	5.91e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDDIGPKE_00868	7.68e-252	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDDIGPKE_00869	1.6e-146	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HDDIGPKE_00870	7.83e-140	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDDIGPKE_00871	2.79e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDDIGPKE_00872	1.9e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDDIGPKE_00873	1.57e-148	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDDIGPKE_00874	2.74e-203	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_00875	3.42e-313	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_00876	3.11e-249	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDDIGPKE_00877	0.0	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00878	1.02e-203	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDDIGPKE_00879	2.8e-198	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HDDIGPKE_00880	1.95e-06	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HDDIGPKE_00882	2.82e-83	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDDIGPKE_00883	1.87e-283	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HDDIGPKE_00884	4.4e-132	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	HD superfamily hydrolase involved in NAD metabolism
HDDIGPKE_00885	4.67e-146	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDDIGPKE_00886	8.86e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
HDDIGPKE_00887	1.71e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDDIGPKE_00888	4.93e-216	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDDIGPKE_00889	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDDIGPKE_00890	8.34e-155	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDDIGPKE_00891	3.73e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDDIGPKE_00892	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDDIGPKE_00893	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDDIGPKE_00894	6.29e-217	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HDDIGPKE_00895	6.57e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDIGPKE_00896	1.52e-64	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDDIGPKE_00897	1.32e-112	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00899	2.31e-155	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDDIGPKE_00900	6.35e-276	-	-	-	T	-	-	-	diguanylate cyclase
HDDIGPKE_00901	1.75e-275	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDDIGPKE_00902	2.12e-274	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
HDDIGPKE_00903	0.0	-	-	CE1	Q	ko:K03932	-	ko00000	Esterase PHB depolymerase
HDDIGPKE_00904	1.69e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDDIGPKE_00905	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HDDIGPKE_00906	8.24e-306	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	xanthine uracil permease family protein K06901
HDDIGPKE_00907	0.0	-	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16C associated
HDDIGPKE_00909	3.36e-224	mglC	-	-	G	ko:K10541	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00910	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HDDIGPKE_00911	7.39e-225	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HDDIGPKE_00912	1.34e-102	-	-	-	C	ko:K03617	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00913	1.73e-160	-	-	-	C	ko:K03613	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00914	1.21e-241	-	-	-	C	ko:K03614	-	ko00000	Belongs to the NqrB RnfD family
HDDIGPKE_00915	2.06e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDDIGPKE_00916	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HDDIGPKE_00917	9.8e-167	-	-	-	T	-	-	-	response regulator receiver
HDDIGPKE_00918	2.25e-104	-	-	-	-	-	-	-	-
HDDIGPKE_00919	1.84e-72	-	-	-	-	ko:K07726	-	ko00000,ko03000	-
HDDIGPKE_00920	4.59e-158	-	-	-	E	-	-	-	Filamentation induced by cAMP protein fic
HDDIGPKE_00923	6.85e-227	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HDDIGPKE_00925	8.89e-218	-	-	-	L	-	-	-	YqaJ viral recombinase family
HDDIGPKE_00926	1.37e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HDDIGPKE_00927	2.72e-158	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HDDIGPKE_00928	1.52e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDDIGPKE_00929	9.26e-227	-	-	-	-	-	-	-	-
HDDIGPKE_00930	3.2e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
HDDIGPKE_00931	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDDIGPKE_00932	7.67e-250	-	-	-	S	-	-	-	Sel1-like repeats.
HDDIGPKE_00933	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDDIGPKE_00934	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system ATPase and permease
HDDIGPKE_00935	1.7e-47	-	-	-	U	ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	mttA/Hcf106 family
HDDIGPKE_00936	2.4e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
HDDIGPKE_00937	9.53e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDDIGPKE_00938	0.0	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDDIGPKE_00939	9.52e-205	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00940	8.54e-54	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HDDIGPKE_00941	5.95e-149	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00942	1.01e-44	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HDDIGPKE_00943	1.49e-97	-	-	-	K	-	-	-	Transcriptional regulator
HDDIGPKE_00947	3.23e-217	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDDIGPKE_00948	3.12e-293	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HDDIGPKE_00949	9.07e-198	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDDIGPKE_00950	7.69e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDDIGPKE_00951	2.88e-220	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDDIGPKE_00952	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDDIGPKE_00953	5.28e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDDIGPKE_00954	1.44e-235	-	-	-	S	ko:K07035	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00955	7.24e-283	-	-	-	M	-	-	-	hydrolase, family 25
HDDIGPKE_00956	1.35e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00957	7.83e-159	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00958	5.87e-155	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_00959	1.27e-149	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00960	1.06e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_00961	3.24e-63	-	-	-	-	-	-	-	-
HDDIGPKE_00962	2.02e-160	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	Psort location Cytoplasmic, score
HDDIGPKE_00963	8.22e-213	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_00964	8.61e-89	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HDDIGPKE_00965	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HDDIGPKE_00966	2.09e-26	-	-	-	DZ	-	-	-	guanyl-nucleotide exchange factor activity
HDDIGPKE_00967	2.25e-150	-	-	-	C	-	-	-	NADPH-dependent FMN reductase
HDDIGPKE_00968	6.76e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HDDIGPKE_00969	2.05e-16	rhlE	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HDDIGPKE_00970	5.77e-209	rlmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase
HDDIGPKE_00971	3.77e-291	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 7.50
HDDIGPKE_00972	5.23e-311	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_00973	0.0	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HDDIGPKE_00975	4.8e-116	-	-	-	-	-	-	-	-
HDDIGPKE_00976	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	Transcriptional regulator, GntR family
HDDIGPKE_00977	3.12e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_00978	8.94e-259	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HDDIGPKE_00979	5.4e-118	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
HDDIGPKE_00981	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDDIGPKE_00982	2.92e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDDIGPKE_00983	9.86e-84	-	-	-	S	-	-	-	NAD-specific glutamate dehydrogenase
HDDIGPKE_00984	1.35e-201	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
HDDIGPKE_00985	2.89e-124	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
HDDIGPKE_00986	3.27e-83	-	-	-	K	-	-	-	iron dependent repressor
HDDIGPKE_00987	9.96e-264	-	-	-	T	-	-	-	diguanylate cyclase
HDDIGPKE_00988	0.0	-	2.7.11.1	-	KL	ko:K08282	-	ko00000,ko01000	SNF2 family
HDDIGPKE_00989	4.36e-239	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HDDIGPKE_00990	3.94e-174	yfcA	-	-	S	ko:K07090	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_00991	1.02e-199	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDDIGPKE_00992	1.1e-81	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_00993	2.18e-117	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDDIGPKE_00994	3.13e-148	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HDDIGPKE_00995	2.29e-308	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDDIGPKE_00996	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDDIGPKE_00997	3.89e-87	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDDIGPKE_00998	7.23e-51	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDDIGPKE_00999	5.45e-231	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDIGPKE_01000	1.46e-239	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDDIGPKE_01001	1.45e-238	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDIGPKE_01002	1.75e-201	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDIGPKE_01003	2.99e-124	-	-	-	-	-	-	-	-
HDDIGPKE_01004	2.23e-181	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
HDDIGPKE_01005	1.27e-155	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HDDIGPKE_01006	8.01e-143	-	-	-	M	-	-	-	Chain length determinant protein
HDDIGPKE_01007	1.5e-202	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDIGPKE_01008	6.1e-258	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDDIGPKE_01009	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	transport systems ATPase components
HDDIGPKE_01010	7.61e-254	tmpC	-	-	S	ko:K07335	-	ko00000	basic membrane
HDDIGPKE_01011	1.3e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDDIGPKE_01012	6.11e-169	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine-nucleoside phosphorylase
HDDIGPKE_01013	6.32e-298	-	-	-	D	-	-	-	G5
HDDIGPKE_01014	6.02e-217	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDIGPKE_01016	6.38e-181	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDIGPKE_01017	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	TIGRFAM formate acetyltransferase
HDDIGPKE_01019	3.57e-237	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDDIGPKE_01020	0.0	-	-	-	M	-	-	-	Glycosyl-transferase family 4
HDDIGPKE_01022	6.06e-274	-	-	-	G	-	-	-	Acyltransferase family
HDDIGPKE_01023	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location Cytoplasmic, score
HDDIGPKE_01024	7.32e-46	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Acyl carrier protein
HDDIGPKE_01025	3.42e-279	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HDDIGPKE_01026	3.35e-250	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HDDIGPKE_01027	9.17e-150	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDDIGPKE_01028	4.13e-38	ynzC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF896)
HDDIGPKE_01029	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01030	2.22e-34	-	-	-	-	-	-	-	-
HDDIGPKE_01032	1.77e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_01033	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01034	0.0	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
HDDIGPKE_01035	2.46e-35	-	-	-	L	-	-	-	Addiction module antitoxin
HDDIGPKE_01036	2.55e-49	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	addiction module toxin, Txe YoeB family
HDDIGPKE_01037	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDDIGPKE_01038	1.56e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDDIGPKE_01039	2.64e-212	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDDIGPKE_01040	3.06e-238	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
HDDIGPKE_01041	2.06e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01042	6.31e-51	-	-	-	S	-	-	-	SPP1 phage holin
HDDIGPKE_01043	1.29e-31	-	-	-	-	-	-	-	-
HDDIGPKE_01044	4.05e-67	-	3.4.17.14	-	M	ko:K08640	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15A
HDDIGPKE_01047	2.47e-198	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDDIGPKE_01048	1.57e-300	-	-	-	E	-	-	-	Peptidase dimerisation domain
HDDIGPKE_01049	1.31e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
HDDIGPKE_01050	0.0	glpA	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HDDIGPKE_01051	4.49e-297	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01052	2.24e-81	-	-	-	S	-	-	-	protein with conserved CXXC pairs
HDDIGPKE_01053	6.74e-244	modC	3.6.3.29	-	E	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDDIGPKE_01054	2.48e-151	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdate ABC transporter
HDDIGPKE_01055	3.63e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, periplasmic molybdate-binding protein
HDDIGPKE_01056	1.43e-223	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
HDDIGPKE_01057	6.91e-234	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDDIGPKE_01058	1.72e-109	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HDDIGPKE_01059	3.13e-253	moeA2	-	-	H	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01060	4.98e-101	mobB	2.7.7.77	-	H	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Molybdopterin-guanine dinucleotide biosynthesis protein
HDDIGPKE_01061	1.8e-289	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA C-terminal region (domain IV)
HDDIGPKE_01062	2.22e-204	-	-	-	-	-	-	-	-
HDDIGPKE_01063	6.91e-96	-	1.2.7.5	-	C	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Aldehyde ferredoxin oxidoreductase, N-terminal domain
HDDIGPKE_01064	0.0	cstA	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01065	1.31e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HDDIGPKE_01067	1.5e-128	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDIGPKE_01068	8.23e-291	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01069	0.0	-	-	-	S	-	-	-	DNA replication and repair protein RecF
HDDIGPKE_01070	9.83e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HDDIGPKE_01071	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01075	1.07e-68	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDDIGPKE_01076	9.11e-134	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
HDDIGPKE_01077	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HDDIGPKE_01078	8.58e-174	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
HDDIGPKE_01079	1.75e-134	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDDIGPKE_01080	4.95e-57	-	-	-	C	-	-	-	Hydrid cluster protein-associated redox disulfide domain
HDDIGPKE_01081	2.19e-193	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01082	1.55e-148	-	-	-	K	-	-	-	Belongs to the P(II) protein family
HDDIGPKE_01083	1.73e-300	-	-	-	T	-	-	-	Protein of unknown function (DUF1538)
HDDIGPKE_01084	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HDDIGPKE_01085	6.58e-130	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HDDIGPKE_01086	4.01e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HDDIGPKE_01087	2.23e-121	-	-	-	-	-	-	-	-
HDDIGPKE_01088	5.26e-249	-	-	-	M	-	-	-	lipoprotein YddW precursor K01189
HDDIGPKE_01092	8.61e-25	-	-	-	L	-	-	-	Phage integrase family
HDDIGPKE_01095	3.36e-72	-	-	-	S	ko:K06987	-	ko00000	Succinylglutamate desuccinylase aspartoacylase
HDDIGPKE_01097	1.28e-201	-	-	-	S	-	-	-	O-Antigen ligase
HDDIGPKE_01098	5.46e-300	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
HDDIGPKE_01099	2.27e-307	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HDDIGPKE_01100	3.23e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HDDIGPKE_01101	6.77e-214	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HDDIGPKE_01102	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HDDIGPKE_01103	1.89e-168	-	-	-	T	-	-	-	response regulator
HDDIGPKE_01104	4.55e-207	-	-	-	T	-	-	-	GHKL domain
HDDIGPKE_01106	3.26e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HDDIGPKE_01107	3.39e-313	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDDIGPKE_01108	1.31e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDDIGPKE_01110	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HDDIGPKE_01111	1.01e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HDDIGPKE_01112	0.0	dsdA	4.3.1.18	-	H	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HDDIGPKE_01114	1.64e-293	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HDDIGPKE_01115	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
HDDIGPKE_01116	7.78e-125	-	-	-	-	-	-	-	-
HDDIGPKE_01117	0.0	-	-	-	T	-	-	-	Histidine kinase
HDDIGPKE_01118	1.67e-182	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDIGPKE_01119	1.23e-171	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HDDIGPKE_01120	1.68e-120	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
HDDIGPKE_01121	2.59e-50	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDIGPKE_01122	1.53e-46	hslR	-	-	J	-	-	-	S4 domain protein
HDDIGPKE_01123	6.05e-09	yabP	-	-	S	-	-	-	Sporulation protein YabP
HDDIGPKE_01124	9.44e-58	-	-	-	-	-	-	-	-
HDDIGPKE_01125	5.4e-44	-	-	-	D	ko:K13052	-	ko00000,ko03036	septum formation initiator
HDDIGPKE_01126	1.27e-95	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	S1 RNA binding domain
HDDIGPKE_01127	2.86e-288	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDDIGPKE_01128	5.92e-201	-	-	-	-	-	-	-	-
HDDIGPKE_01129	3.35e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01130	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDDIGPKE_01131	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HDDIGPKE_01132	1.7e-243	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
HDDIGPKE_01133	1.25e-102	-	-	-	KT	-	-	-	Transcriptional regulator
HDDIGPKE_01134	0.0	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin transporter
HDDIGPKE_01136	6.11e-38	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDDIGPKE_01137	3.5e-92	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDDIGPKE_01138	8.2e-304	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDIGPKE_01139	1.01e-156	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HDDIGPKE_01140	4.42e-120	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDDIGPKE_01144	1.2e-22	-	-	-	S	-	-	-	Cro/C1-type HTH DNA-binding domain
HDDIGPKE_01145	1.84e-45	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HDDIGPKE_01146	1.21e-29	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HDDIGPKE_01147	5.58e-134	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	BRO family, N-terminal domain
HDDIGPKE_01148	5.31e-44	-	-	-	-	-	-	-	-
HDDIGPKE_01149	2.4e-23	-	-	-	-	-	-	-	-
HDDIGPKE_01151	1.27e-37	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDDIGPKE_01152	1.29e-36	-	-	-	L	-	-	-	DnaD domain protein
HDDIGPKE_01155	5.67e-05	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HDDIGPKE_01156	1.46e-265	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDIGPKE_01157	2.71e-38	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01158	8.44e-278	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
HDDIGPKE_01159	5.32e-208	-	-	-	JK	-	-	-	Acetyltransferase (GNAT) family
HDDIGPKE_01160	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDDIGPKE_01161	1.36e-241	-	-	-	C	ko:K18471	ko00640,map00640	ko00000,ko00001,ko01000	Aldo/keto reductase family
HDDIGPKE_01162	3.32e-145	-	-	-	K	ko:K01420	-	ko00000,ko03000	Psort location Cytoplasmic, score
HDDIGPKE_01163	1.95e-188	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	pyridine
HDDIGPKE_01164	7.89e-245	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HDDIGPKE_01165	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDDIGPKE_01166	5.66e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01167	4.33e-40	-	-	-	S	-	-	-	Psort location
HDDIGPKE_01168	2.83e-191	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDDIGPKE_01169	1.77e-281	alaXL	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Threonine alanine tRNA ligase second additional domain protein
HDDIGPKE_01170	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01171	1.03e-208	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01172	7.39e-92	-	-	-	S	-	-	-	FMN_bind
HDDIGPKE_01173	1.59e-202	-	-	-	C	-	-	-	FMN-binding domain protein
HDDIGPKE_01174	1.46e-299	-	-	-	S	-	-	-	Penicillin-binding protein Tp47 domain a
HDDIGPKE_01175	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_01176	3.72e-189	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDDIGPKE_01177	1.74e-107	-	-	-	S	-	-	-	small multi-drug export protein
HDDIGPKE_01178	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01179	4.31e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF3842)
HDDIGPKE_01180	4.41e-133	-	-	-	S	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HDDIGPKE_01181	2.29e-48	-	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
HDDIGPKE_01183	2.88e-219	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	exonuclease SbcC
HDDIGPKE_01184	7.31e-38	-	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HDDIGPKE_01185	1.08e-78	-	-	-	P	-	-	-	Belongs to the ArsC family
HDDIGPKE_01186	9.32e-184	-	-	-	-	-	-	-	-
HDDIGPKE_01187	2.02e-246	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDDIGPKE_01188	3.26e-63	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HDDIGPKE_01189	4.21e-134	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01190	8.34e-66	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01191	1.66e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HDDIGPKE_01192	1.32e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
HDDIGPKE_01193	2.62e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDDIGPKE_01194	1.26e-154	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDDIGPKE_01195	0.0	-	1.5.1.20, 2.1.1.10	-	H	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	homocysteine S-methyltransferase
HDDIGPKE_01196	1.26e-79	epsJ2	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.97
HDDIGPKE_01197	4.58e-312	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01199	2.85e-207	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HDDIGPKE_01200	1.07e-172	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDIGPKE_01201	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01202	1.22e-282	-	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01203	1.02e-314	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDDIGPKE_01204	2.41e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDDIGPKE_01205	1.01e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDDIGPKE_01206	6.18e-115	thiW	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01207	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyltransferase family 36
HDDIGPKE_01208	4.63e-195	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HDDIGPKE_01209	1.58e-81	-	-	-	G	-	-	-	Aldolase
HDDIGPKE_01210	1.04e-286	-	-	-	P	-	-	-	arsenite transmembrane transporter activity
HDDIGPKE_01211	1.52e-264	pdxA	1.1.1.262, 1.1.1.408, 1.1.1.409	-	C	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HDDIGPKE_01212	7.92e-218	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
HDDIGPKE_01213	1.76e-277	-	-	-	C	-	-	-	alcohol dehydrogenase
HDDIGPKE_01214	3.66e-303	-	-	-	G	-	-	-	BNR repeat-like domain
HDDIGPKE_01215	5.83e-291	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative sugar-binding N-terminal domain
HDDIGPKE_01216	0.0	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	phosphorelay signal transduction system
HDDIGPKE_01217	2.68e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01218	2.82e-83	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDDIGPKE_01219	1.6e-171	-	-	-	E	-	-	-	Pyridoxal-phosphate dependent protein
HDDIGPKE_01220	4.79e-307	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HDDIGPKE_01221	2.42e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDDIGPKE_01222	1.79e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HDDIGPKE_01223	2.38e-160	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HDDIGPKE_01224	1.19e-93	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HDDIGPKE_01225	2.4e-278	-	-	-	-	-	-	-	-
HDDIGPKE_01226	1.65e-276	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDDIGPKE_01227	8.16e-133	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDDIGPKE_01228	9.6e-170	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDIGPKE_01229	9.26e-209	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDDIGPKE_01230	1.16e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDDIGPKE_01231	2.67e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01232	3.74e-186	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDIGPKE_01233	2.38e-62	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDDIGPKE_01234	4.63e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDDIGPKE_01235	7.73e-256	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HDDIGPKE_01236	6.57e-176	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HDDIGPKE_01237	8.73e-205	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDDIGPKE_01238	1.51e-178	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HDDIGPKE_01240	5.63e-281	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDDIGPKE_01241	1.05e-191	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDDIGPKE_01242	7.83e-15	-	-	-	E	-	-	-	Parallel beta-helix repeats
HDDIGPKE_01243	2.33e-161	-	-	-	-	-	-	-	-
HDDIGPKE_01244	1.23e-229	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HDDIGPKE_01245	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HDDIGPKE_01246	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HDDIGPKE_01247	2.95e-234	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDDIGPKE_01248	1.22e-295	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HDDIGPKE_01249	1.1e-245	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDDIGPKE_01251	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	HD domain
HDDIGPKE_01252	1.76e-160	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine O-acetyltransferase
HDDIGPKE_01254	5.84e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDDIGPKE_01256	7.07e-250	lldD	-	-	C	-	-	-	FMN-dependent dehydrogenase
HDDIGPKE_01257	1.36e-215	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDIGPKE_01258	1.99e-148	-	-	-	-	-	-	-	-
HDDIGPKE_01259	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDDIGPKE_01260	1.96e-75	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score
HDDIGPKE_01261	6.61e-123	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HDDIGPKE_01262	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score
HDDIGPKE_01263	2.82e-237	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Psort location Cytoplasmic, score
HDDIGPKE_01264	2.95e-138	rnmV	3.1.26.8	-	L	ko:K05985	-	ko00000,ko01000	Ribonuclease M5
HDDIGPKE_01265	1.85e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01266	0.0	glvC	2.7.1.199, 2.7.1.208	-	G	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01267	2.22e-192	licT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
HDDIGPKE_01268	2.6e-96	-	-	-	-	-	-	-	-
HDDIGPKE_01269	1.52e-264	-	-	-	C	ko:K07138	-	ko00000	Psort location Cytoplasmic, score
HDDIGPKE_01270	1.29e-268	clcA	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01271	1.25e-179	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDDIGPKE_01272	1.07e-94	trkA2	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HDDIGPKE_01273	1.1e-158	-	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HDDIGPKE_01275	0.0	-	-	-	-	-	-	-	-
HDDIGPKE_01276	1.06e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	phosphoglycolate phosphatase, bacterial
HDDIGPKE_01277	9.24e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HDDIGPKE_01278	8.13e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HDDIGPKE_01280	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDIGPKE_01281	3.63e-214	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01282	3.78e-307	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HDDIGPKE_01285	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01286	4.49e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01287	1.14e-195	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDDIGPKE_01288	1.72e-302	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDIGPKE_01289	8.7e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDDIGPKE_01290	2.97e-93	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HDDIGPKE_01291	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDDIGPKE_01292	9.48e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDDIGPKE_01293	1.1e-178	-	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HDDIGPKE_01294	6.09e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDDIGPKE_01295	0.0	tetP	-	-	J	-	-	-	elongation factor G
HDDIGPKE_01296	5.16e-214	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01297	0.0	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01298	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HDDIGPKE_01299	1.85e-19	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_01300	8.07e-174	-	-	-	U	-	-	-	domain, Protein
HDDIGPKE_01301	9.35e-97	-	5.1.1.1	-	K	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	helix_turn _helix lactose operon repressor
HDDIGPKE_01302	2.78e-205	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01303	3.67e-164	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDDIGPKE_01304	1.79e-286	-	-	-	T	-	-	-	GHKL domain
HDDIGPKE_01305	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HDDIGPKE_01306	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
HDDIGPKE_01307	1.02e-59	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDDIGPKE_01308	9.78e-231	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01309	8.74e-194	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
HDDIGPKE_01310	6.59e-52	-	-	-	-	-	-	-	-
HDDIGPKE_01311	2.23e-65	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HDDIGPKE_01315	1.08e-53	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01316	6.8e-151	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDDIGPKE_01317	2.19e-38	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDIGPKE_01318	1.57e-95	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDDIGPKE_01319	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDDIGPKE_01320	2.53e-208	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDDIGPKE_01321	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDDIGPKE_01322	4.73e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDDIGPKE_01323	6.12e-77	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01324	0.0	-	-	-	L	-	-	-	domain protein
HDDIGPKE_01325	2.68e-274	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDIGPKE_01326	6.99e-33	-	-	-	-	-	-	-	-
HDDIGPKE_01327	0.0	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HDDIGPKE_01328	1.3e-43	-	-	-	-	-	-	-	-
HDDIGPKE_01329	1.5e-128	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HDDIGPKE_01330	0.0	-	-	-	S	-	-	-	ABC transporter substrate-binding protein PnrA-like
HDDIGPKE_01331	1.74e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
HDDIGPKE_01332	1.15e-81	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01335	1.74e-307	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01336	3.78e-248	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
HDDIGPKE_01337	0.0	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDIGPKE_01338	4.18e-176	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDDIGPKE_01339	2.64e-243	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HDDIGPKE_01340	1.28e-254	-	-	-	S	-	-	-	Acyltransferase family
HDDIGPKE_01341	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDDIGPKE_01342	4.75e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDIGPKE_01343	2.71e-103	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01344	4.28e-276	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDDIGPKE_01345	1.25e-118	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDIGPKE_01346	1.75e-275	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HDDIGPKE_01347	4.21e-245	-	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HDDIGPKE_01349	2.51e-165	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01350	1.76e-62	-	-	-	S	-	-	-	regulation of response to stimulus
HDDIGPKE_01351	1.24e-164	-	-	-	K	-	-	-	Helix-turn-helix
HDDIGPKE_01356	6.04e-272	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDDIGPKE_01357	4.83e-266	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HDDIGPKE_01358	1.95e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDDIGPKE_01360	2.79e-206	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDDIGPKE_01361	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDDIGPKE_01362	1.78e-209	-	-	-	K	-	-	-	LysR substrate binding domain protein
HDDIGPKE_01363	5.21e-182	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01364	1.64e-84	-	-	-	L	-	-	-	Dinitrogenase iron-molybdenum cofactor
HDDIGPKE_01365	2.29e-225	-	-	-	G	-	-	-	Aldose 1-epimerase
HDDIGPKE_01367	1.29e-164	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	SAF domain protein
HDDIGPKE_01368	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01369	8.99e-157	metH2	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Vitamin B12 dependent methionine synthase activation
HDDIGPKE_01371	1.62e-70	-	-	-	T	-	-	-	Hpt domain
HDDIGPKE_01372	7.81e-238	-	1.1.1.79, 1.1.1.81	-	EH	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDDIGPKE_01373	3.25e-74	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HDDIGPKE_01374	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glutaminyl-tRNA synthetase
HDDIGPKE_01375	1.83e-202	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01376	3.5e-100	-	-	-	K	-	-	-	transcriptional regulator
HDDIGPKE_01378	1.64e-70	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDDIGPKE_01379	2.33e-175	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01381	1.72e-303	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HDDIGPKE_01382	1.83e-281	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDDIGPKE_01383	1.81e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HDDIGPKE_01384	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HDDIGPKE_01385	5.08e-207	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDDIGPKE_01386	5.2e-64	-	-	-	-	-	-	-	-
HDDIGPKE_01387	2.91e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01388	4.7e-38	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDDIGPKE_01389	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HDDIGPKE_01390	3.53e-139	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDIGPKE_01391	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDDIGPKE_01392	1.18e-254	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HDDIGPKE_01393	2.23e-282	-	-	-	P	-	-	-	Transporter, CPA2 family
HDDIGPKE_01394	6.32e-55	-	-	-	K	ko:K06284	-	ko00000,ko03000	Transcriptional regulator, AbrB family
HDDIGPKE_01395	1.44e-228	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HDDIGPKE_01396	4.97e-158	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HDDIGPKE_01398	0.0	-	-	-	S	-	-	-	Terminase-like family
HDDIGPKE_01399	0.0	-	-	-	-	-	-	-	-
HDDIGPKE_01400	1.53e-130	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HDDIGPKE_01401	2.34e-240	-	-	-	-	-	-	-	-
HDDIGPKE_01404	0.0	-	-	-	-	-	-	-	-
HDDIGPKE_01406	2.22e-238	-	-	-	-	-	-	-	-
HDDIGPKE_01408	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDDIGPKE_01410	1.81e-309	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HDDIGPKE_01411	8.61e-291	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major Facilitator
HDDIGPKE_01412	1.57e-193	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01413	5.48e-206	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDDIGPKE_01414	9.26e-149	-	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid ABC transporter
HDDIGPKE_01415	4.62e-182	tcyN	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Amino acid ABC transporter ATP-binding protein, PAAT family
HDDIGPKE_01416	2.88e-185	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
HDDIGPKE_01417	0.0	-	-	-	C	-	-	-	FeS-containing Cyanobacterial-specific oxidoreductase
HDDIGPKE_01418	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDDIGPKE_01419	3.39e-145	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDDIGPKE_01420	5.44e-116	-	-	-	S	-	-	-	Psort location
HDDIGPKE_01421	4.93e-208	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HDDIGPKE_01423	1.29e-312	-	-	-	V	-	-	-	MatE
HDDIGPKE_01424	5.57e-115	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HDDIGPKE_01425	8.94e-195	-	-	-	-	-	-	-	-
HDDIGPKE_01426	4.73e-146	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HDDIGPKE_01427	1.67e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDDIGPKE_01428	8.89e-306	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HDDIGPKE_01429	1.7e-149	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_01430	3.57e-238	-	-	-	G	-	-	-	Major Facilitator Superfamily
HDDIGPKE_01431	4.99e-155	-	-	-	M	-	-	-	Peptidase, M23 family
HDDIGPKE_01432	4.94e-294	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HDDIGPKE_01433	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HDDIGPKE_01434	7.03e-167	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDIGPKE_01435	1.59e-57	-	-	-	P	ko:K10194	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDDIGPKE_01436	4.55e-34	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDIGPKE_01437	1.33e-123	-	-	-	K	-	-	-	Acetyltransferase GNAT family
HDDIGPKE_01438	7.76e-181	yoaP	-	-	E	-	-	-	YoaP-like
HDDIGPKE_01439	1.23e-47	-	-	-	S	-	-	-	RNHCP domain
HDDIGPKE_01440	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HDDIGPKE_01441	0.0	-	3.1.3.5, 3.6.1.45	-	FG	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Bacterial extracellular solute-binding protein
HDDIGPKE_01442	2.87e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01443	0.0	hcp	1.7.99.1	-	P	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Prismane/CO dehydrogenase family
HDDIGPKE_01444	1.19e-141	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HDDIGPKE_01445	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDDIGPKE_01446	5.98e-267	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HDDIGPKE_01447	3.04e-261	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP-glucose 4-epimerase
HDDIGPKE_01448	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HDDIGPKE_01449	4.51e-50	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDDIGPKE_01450	4.74e-267	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDDIGPKE_01453	6.68e-283	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HDDIGPKE_01454	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01455	9.9e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HDDIGPKE_01456	2.86e-179	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Serine-type D-Ala-D-Ala carboxypeptidase
HDDIGPKE_01457	5.75e-98	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HDDIGPKE_01458	2.48e-229	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HDDIGPKE_01459	3.41e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HDDIGPKE_01461	2.69e-185	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDDIGPKE_01462	2.29e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDDIGPKE_01463	3.74e-108	-	-	-	K	-	-	-	dihydroxyacetone kinase regulator
HDDIGPKE_01464	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HDDIGPKE_01465	8.08e-267	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01466	0.0	cat	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HDDIGPKE_01467	7.47e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDDIGPKE_01468	1.04e-250	-	2.8.1.7	-	H	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HDDIGPKE_01469	8.68e-311	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01470	3.67e-131	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01472	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HDDIGPKE_01473	3.38e-74	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HDDIGPKE_01474	4.71e-193	-	-	-	S	-	-	-	Putative esterase
HDDIGPKE_01475	7.62e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4250)
HDDIGPKE_01476	6.63e-150	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
HDDIGPKE_01477	7.18e-145	-	-	-	S	-	-	-	YheO-like PAS domain
HDDIGPKE_01478	2.17e-81	TdcF	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HDDIGPKE_01479	5.72e-302	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HDDIGPKE_01480	6.35e-276	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
HDDIGPKE_01481	1.39e-277	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDDIGPKE_01482	8.24e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	PFAM Aminotransferase class I and II
HDDIGPKE_01483	2.22e-299	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HDDIGPKE_01485	9.1e-148	-	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotate phosphoribosyltransferase
HDDIGPKE_01486	6.26e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01487	4.11e-312	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDDIGPKE_01488	1.65e-202	-	-	-	S	-	-	-	Putative esterase
HDDIGPKE_01489	5.5e-194	-	-	-	S	-	-	-	Putative esterase
HDDIGPKE_01490	2.76e-273	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDDIGPKE_01491	1.63e-153	-	-	-	S	-	-	-	IA, variant 3
HDDIGPKE_01492	7.28e-177	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDDIGPKE_01493	1.68e-259	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDDIGPKE_01494	3.94e-272	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HDDIGPKE_01495	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDDIGPKE_01496	2.35e-47	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HDDIGPKE_01497	1.03e-111	-	-	-	-	-	-	-	-
HDDIGPKE_01498	1.63e-177	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDDIGPKE_01499	2.72e-56	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDIGPKE_01500	1.75e-99	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDDIGPKE_01501	1.28e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDIGPKE_01502	3.89e-247	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HDDIGPKE_01503	7.49e-118	-	-	-	-	-	-	-	-
HDDIGPKE_01504	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA synthetase
HDDIGPKE_01505	2.73e-210	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score
HDDIGPKE_01506	5.12e-30	-	-	-	-	-	-	-	-
HDDIGPKE_01507	6.57e-310	-	-	-	M	-	-	-	Peptidase, M23 family
HDDIGPKE_01510	1.42e-171	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDDIGPKE_01511	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDDIGPKE_01512	1.29e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDDIGPKE_01513	6.37e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
HDDIGPKE_01514	3.76e-244	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HDDIGPKE_01515	3.25e-107	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDDIGPKE_01516	2.84e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDDIGPKE_01517	6.76e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDDIGPKE_01518	2.85e-132	-	-	-	S	-	-	-	Radical SAM-linked protein
HDDIGPKE_01519	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HDDIGPKE_01520	2.61e-106	-	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Peptidase M50
HDDIGPKE_01521	1.05e-113	-	-	-	M	-	-	-	Peptidase family M23
HDDIGPKE_01522	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDDIGPKE_01523	4.21e-72	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HDDIGPKE_01524	8.63e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDIGPKE_01525	2.56e-116	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDIGPKE_01526	9.1e-192	-	-	GT2,GT4	M	ko:K07011,ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 21
HDDIGPKE_01527	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HDDIGPKE_01528	9.17e-208	-	-	-	D	ko:K06381	-	ko00000	sporulation resulting in formation of a cellular spore
HDDIGPKE_01530	1.83e-311	-	-	-	L	-	-	-	Phage integrase family
HDDIGPKE_01531	8.91e-28	-	-	-	K	-	-	-	Helix-turn-helix domain
HDDIGPKE_01532	7.48e-194	-	-	-	K	-	-	-	DNA binding
HDDIGPKE_01533	1.86e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDDIGPKE_01534	2.3e-227	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyridine binding domain protein
HDDIGPKE_01535	9.52e-204	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HDDIGPKE_01536	5.42e-117	-	-	-	S	ko:K16788	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01537	8.08e-154	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDDIGPKE_01538	0.0	-	3.1.3.48	-	K	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HDDIGPKE_01539	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDDIGPKE_01540	5.63e-179	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDDIGPKE_01542	8.48e-302	-	-	-	V	-	-	-	MviN-like protein
HDDIGPKE_01543	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HDDIGPKE_01544	7.55e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HDDIGPKE_01545	1.82e-231	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01546	6.08e-181	cstA	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01547	2.9e-208	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HDDIGPKE_01548	2.61e-73	PaaY	-	-	S	ko:K02617	-	ko00000	Bacterial transferase hexapeptide repeat protein
HDDIGPKE_01549	1.51e-297	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDDIGPKE_01550	8.73e-186	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
HDDIGPKE_01551	1.21e-83	yfcE1	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HDDIGPKE_01552	5.62e-191	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDDIGPKE_01553	3.96e-157	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HDDIGPKE_01554	8.06e-17	-	-	-	C	-	-	-	4Fe-4S binding domain
HDDIGPKE_01555	6.19e-112	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HDDIGPKE_01556	0.0	-	-	-	C	-	-	-	UPF0313 protein
HDDIGPKE_01557	0.0	spoIIIE	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDDIGPKE_01558	2.92e-161	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score
HDDIGPKE_01559	1.35e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDDIGPKE_01560	1.59e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDDIGPKE_01561	1.08e-305	-	-	-	S	-	-	-	Tetratricopeptide repeat
HDDIGPKE_01562	5.44e-165	-	-	-	K	-	-	-	response regulator receiver
HDDIGPKE_01563	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HDDIGPKE_01564	3.81e-226	prmC	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01565	3.61e-219	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDDIGPKE_01566	1.41e-266	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDDIGPKE_01567	1.59e-105	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HDDIGPKE_01568	1.44e-275	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HDDIGPKE_01569	6.21e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDDIGPKE_01570	1.39e-96	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HDDIGPKE_01571	0.0	gltA2	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HDDIGPKE_01572	4.89e-95	-	-	-	-	-	-	-	-
HDDIGPKE_01573	6.52e-219	-	-	-	J	ko:K02238	-	ko00000,ko00002,ko02044	Metallo-beta-lactamase domain protein
HDDIGPKE_01574	1.06e-278	-	-	-	C	-	-	-	UPF0313 protein
HDDIGPKE_01575	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDDIGPKE_01576	2.94e-169	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDDIGPKE_01577	7.54e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein
HDDIGPKE_01578	1.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDDIGPKE_01579	1.47e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
HDDIGPKE_01580	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDIGPKE_01581	5.68e-66	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HDDIGPKE_01582	2.63e-240	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDDIGPKE_01583	2.59e-170	radC	-	-	L	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HDDIGPKE_01584	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDDIGPKE_01585	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDDIGPKE_01586	3.22e-216	-	-	-	S	-	-	-	CAAX protease self-immunity
HDDIGPKE_01587	5.4e-63	-	-	-	S	-	-	-	Putative heavy-metal-binding
HDDIGPKE_01588	1.96e-145	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDDIGPKE_01589	1.59e-288	cshA	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HDDIGPKE_01590	5.07e-62	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	bacterial (prokaryotic) histone like domain
HDDIGPKE_01591	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDDIGPKE_01592	6.1e-229	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01593	1.22e-216	-	-	-	Q	-	-	-	FAH family
HDDIGPKE_01594	2.36e-118	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HDDIGPKE_01595	2.36e-61	-	-	-	S	-	-	-	Trp repressor protein
HDDIGPKE_01596	7.94e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDIGPKE_01597	2.15e-116	nfrA2	-	-	C	-	-	-	Nitroreductase family
HDDIGPKE_01598	5.69e-65	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HDDIGPKE_01599	2.35e-127	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01600	2.31e-238	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDDIGPKE_01601	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDDIGPKE_01602	2.34e-240	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
HDDIGPKE_01603	2.47e-129	yvyE	-	-	S	-	-	-	YigZ family
HDDIGPKE_01604	3.24e-221	-	-	-	M	-	-	-	Cysteine-rich secretory protein family
HDDIGPKE_01605	1.03e-140	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HDDIGPKE_01606	1.12e-65	rcoM2	-	-	KT	ko:K02477,ko:K21696	-	ko00000,ko02022,ko03000	phosphorelay signal transduction system
HDDIGPKE_01607	1.99e-236	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HDDIGPKE_01608	9.87e-159	-	-	-	S	-	-	-	IA, variant 3
HDDIGPKE_01609	1.38e-272	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01610	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDDIGPKE_01611	7.73e-176	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDDIGPKE_01612	1.11e-179	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HDDIGPKE_01613	1.85e-85	rnpA	3.1.26.5	-	J	ko:K03536,ko:K08998	-	ko00000,ko01000,ko03016	ribonuclease P activity
HDDIGPKE_01614	4.21e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDDIGPKE_01615	2.22e-235	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HDDIGPKE_01616	1.71e-197	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HDDIGPKE_01617	0.0	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HDDIGPKE_01618	2.88e-306	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDDIGPKE_01619	2.75e-43	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDDIGPKE_01620	4.65e-208	-	-	-	S	-	-	-	AI-2E family transporter
HDDIGPKE_01622	0.0	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HDDIGPKE_01623	1.32e-221	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01624	6.04e-220	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the DapA family
HDDIGPKE_01625	4.93e-108	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HDDIGPKE_01626	2.58e-163	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDDIGPKE_01627	2.59e-205	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HDDIGPKE_01628	6.97e-157	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01629	2.97e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDDIGPKE_01630	3.72e-110	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDDIGPKE_01632	9.91e-137	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01633	3.92e-141	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01634	3.3e-35	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HDDIGPKE_01635	2.13e-44	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HDDIGPKE_01636	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HDDIGPKE_01639	1e-62	-	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDDIGPKE_01640	8.52e-208	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0160)
HDDIGPKE_01641	8.82e-164	-	-	-	-	-	-	-	-
HDDIGPKE_01642	9.62e-252	-	-	-	P	-	-	-	Belongs to the TelA family
HDDIGPKE_01643	9.03e-138	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HDDIGPKE_01644	1.49e-113	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	UreE urease accessory protein, C-terminal domain
HDDIGPKE_01645	1.48e-219	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDDIGPKE_01646	5.44e-200	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01647	2.12e-85	thiF	-	-	H	ko:K22132	-	ko00000,ko03016	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HDDIGPKE_01648	3.8e-189	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDDIGPKE_01649	1.95e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDDIGPKE_01650	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	PFAM DNA gyrase topoisomerase IV, subunit A
HDDIGPKE_01651	5.84e-252	-	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase
HDDIGPKE_01652	1.27e-264	-	-	-	K	ko:K03556	-	ko00000,ko03000	helix_turn_helix, Lux Regulon
HDDIGPKE_01655	5.66e-203	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDIGPKE_01656	2.17e-139	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HDDIGPKE_01657	0.0	pbg	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HDDIGPKE_01658	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01659	9.89e-188	ytrP	2.7.7.65	-	T	ko:K13069	-	ko00000,ko01000	diguanylate cyclase activity
HDDIGPKE_01660	7.62e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01661	6.87e-229	-	-	-	JM	-	-	-	Nucleotidyl transferase
HDDIGPKE_01662	2.08e-114	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01663	1.17e-82	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDDIGPKE_01665	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HDDIGPKE_01666	4.86e-77	-	-	-	S	-	-	-	NusG domain II
HDDIGPKE_01667	0.0	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDDIGPKE_01668	1.6e-103	nifU	-	-	C	ko:K04488	-	ko00000	Fe-S iron-sulfur cluster assembly protein, NifU family
HDDIGPKE_01669	0.0	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
HDDIGPKE_01670	0.0	-	-	-	S	-	-	-	VWA-like domain (DUF2201)
HDDIGPKE_01671	6.32e-253	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
HDDIGPKE_01672	2.69e-274	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01673	1.34e-54	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDDIGPKE_01674	1.39e-195	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDDIGPKE_01675	1.11e-24	-	-	-	S	-	-	-	ABC-2 family transporter protein
HDDIGPKE_01677	1.02e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDDIGPKE_01678	3.12e-292	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HDDIGPKE_01679	1.63e-300	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HDDIGPKE_01681	9.51e-63	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01682	1.15e-286	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDDIGPKE_01684	1.87e-272	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HDDIGPKE_01685	1.26e-99	-	-	-	-	-	-	-	-
HDDIGPKE_01686	1.1e-80	-	-	-	U	-	-	-	Protein of unknown function (DUF1700)
HDDIGPKE_01687	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDDIGPKE_01688	4.88e-54	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HDDIGPKE_01689	1.85e-304	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDDIGPKE_01690	8.07e-128	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDDIGPKE_01691	1.09e-150	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HDDIGPKE_01692	8.9e-96	spoIIAB	2.7.11.1	-	T	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HDDIGPKE_01693	2.72e-67	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HDDIGPKE_01694	1.02e-279	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydrofolate synthase activity
HDDIGPKE_01695	3.59e-65	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01696	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDDIGPKE_01697	1.62e-295	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01698	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDDIGPKE_01699	1.55e-161	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDDIGPKE_01700	2.08e-264	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HDDIGPKE_01701	6.01e-153	-	-	-	S	ko:K06890	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01702	4.28e-190	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDDIGPKE_01703	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDDIGPKE_01704	1.88e-124	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDDIGPKE_01705	1.09e-221	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDDIGPKE_01706	1.99e-153	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDIGPKE_01707	7.91e-83	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HDDIGPKE_01708	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HDDIGPKE_01709	1.45e-161	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
HDDIGPKE_01711	3.92e-220	tig	-	-	D	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase activity
HDDIGPKE_01712	9.08e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
HDDIGPKE_01713	2.56e-252	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01714	2.15e-195	-	-	-	S	-	-	-	Cof-like hydrolase
HDDIGPKE_01715	1.23e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDDIGPKE_01716	2.42e-205	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDDIGPKE_01717	9.03e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HDDIGPKE_01718	1.81e-85	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDDIGPKE_01719	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDDIGPKE_01720	7.35e-307	-	-	-	V	-	-	-	MATE efflux family protein
HDDIGPKE_01721	4.51e-156	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01722	1.58e-238	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
HDDIGPKE_01723	1.93e-55	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HDDIGPKE_01724	1.93e-87	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HDDIGPKE_01725	5.71e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HDDIGPKE_01726	8.65e-81	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HDDIGPKE_01727	0.0	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HDDIGPKE_01728	8.67e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01729	2.32e-300	rhaB	2.7.1.5	-	H	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Carbohydrate kinase, FGGY family protein
HDDIGPKE_01730	0.0	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HDDIGPKE_01731	8.2e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HDDIGPKE_01732	5.76e-208	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HDDIGPKE_01733	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HDDIGPKE_01734	3.16e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HDDIGPKE_01735	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDDIGPKE_01736	6.01e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_01738	1.85e-240	-	-	-	S	-	-	-	Prokaryotic RING finger family 1
HDDIGPKE_01739	2.97e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDDIGPKE_01740	6.28e-271	napA	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01741	0.0	-	-	-	I	-	-	-	Lipase (class 3)
HDDIGPKE_01742	1.98e-91	-	-	-	S	ko:K06934	-	ko00000	Domain of unknown function (DUF296)
HDDIGPKE_01744	6.44e-66	-	-	-	-	-	-	-	-
HDDIGPKE_01745	1.29e-239	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01746	2.5e-284	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01748	1.32e-131	-	-	-	S	ko:K16789	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_01749	1.24e-47	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
HDDIGPKE_01750	5.59e-173	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDDIGPKE_01751	9.66e-105	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDDIGPKE_01753	4.61e-188	ttcA2	-	-	H	-	-	-	Belongs to the TtcA family
HDDIGPKE_01754	2.2e-293	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDDIGPKE_01756	9.17e-302	-	-	-	Q	-	-	-	Amidohydrolase family
HDDIGPKE_01757	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
HDDIGPKE_01759	5.36e-120	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01760	9.93e-245	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HDDIGPKE_01761	4.99e-180	-	-	-	K	-	-	-	Response regulator receiver domain
HDDIGPKE_01762	0.0	-	-	-	T	-	-	-	Histidine kinase
HDDIGPKE_01763	8.57e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT IMPCHase bienzyme
HDDIGPKE_01764	4.01e-192	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
HDDIGPKE_01765	3.44e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDDIGPKE_01766	4.15e-258	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDDIGPKE_01767	3.94e-85	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDDIGPKE_01769	2.79e-131	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01770	2.47e-134	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
HDDIGPKE_01771	1.82e-160	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01772	7.25e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HDDIGPKE_01773	7.46e-27	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDIGPKE_01774	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDDIGPKE_01776	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDIGPKE_01777	1.43e-69	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDDIGPKE_01778	1.03e-138	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDDIGPKE_01779	2.48e-111	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDDIGPKE_01780	7.92e-289	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDDIGPKE_01781	5.7e-146	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDDIGPKE_01782	1.82e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HDDIGPKE_01783	6.35e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDIGPKE_01784	1.86e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDDIGPKE_01785	6.31e-295	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HDDIGPKE_01786	1.85e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDDIGPKE_01787	4.29e-176	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate ABC transporter
HDDIGPKE_01788	2.21e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDDIGPKE_01789	6.06e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HDDIGPKE_01790	3.88e-283	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDDIGPKE_01791	2.43e-78	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HDDIGPKE_01792	2.35e-286	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HDDIGPKE_01793	1.47e-285	-	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HDDIGPKE_01794	1.74e-292	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDDIGPKE_01795	4.15e-58	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HDDIGPKE_01796	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
HDDIGPKE_01797	2e-109	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDDIGPKE_01798	3.25e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HDDIGPKE_01799	5.44e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDDIGPKE_01800	6.52e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDDIGPKE_01801	2.06e-234	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDDIGPKE_01803	2.14e-56	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDDIGPKE_01804	3.78e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HDDIGPKE_01805	1.4e-196	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDDIGPKE_01806	5.34e-269	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDDIGPKE_01808	6.69e-201	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HDDIGPKE_01809	1.39e-157	cpsE	-	-	M	-	-	-	sugar transferase
HDDIGPKE_01810	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HDDIGPKE_01811	1.1e-61	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDDIGPKE_01812	2.46e-117	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
HDDIGPKE_01813	4.44e-142	nnrE	5.1.99.6	-	G	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HDDIGPKE_01814	4.35e-238	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDDIGPKE_01816	1.06e-258	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HDDIGPKE_01817	8.64e-178	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDIGPKE_01818	3.64e-140	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDDIGPKE_01820	8.49e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF5058)
HDDIGPKE_01821	1.08e-113	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01822	4.74e-106	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDDIGPKE_01823	6e-185	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDDIGPKE_01824	2.71e-301	adh	-	-	C	-	-	-	belongs to the iron- containing alcohol dehydrogenase family
HDDIGPKE_01825	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDDIGPKE_01829	5.14e-167	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate binding protein
HDDIGPKE_01830	1.09e-148	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDDIGPKE_01831	3.09e-139	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDDIGPKE_01832	2.77e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HDDIGPKE_01833	1.78e-241	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	sugar-binding domain protein
HDDIGPKE_01834	2.73e-134	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDDIGPKE_01835	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HDDIGPKE_01837	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HDDIGPKE_01838	1.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
HDDIGPKE_01839	3.4e-175	-	-	-	S	-	-	-	TraX protein
HDDIGPKE_01840	1.02e-232	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HDDIGPKE_01841	2.55e-224	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01842	1.75e-70	-	-	-	L	-	-	-	DNA modification repair radical SAM protein
HDDIGPKE_01843	9.1e-193	-	-	-	L	-	-	-	DNA metabolism protein
HDDIGPKE_01844	2.16e-40	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HDDIGPKE_01845	5.43e-114	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDDIGPKE_01846	7.41e-23	-	-	-	S	ko:K07137	-	ko00000	Oxidoreductase
HDDIGPKE_01847	8.57e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01848	8.31e-161	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDIGPKE_01849	4.18e-271	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HDDIGPKE_01850	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HDDIGPKE_01851	8.93e-226	envE	3.1.4.46, 3.2.1.18, 3.2.1.8	GH33	E	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	ko00000,ko00001,ko01000,ko02042	lipolytic protein G-D-S-L family
HDDIGPKE_01852	1.16e-166	cydC	-	-	V	ko:K06148	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01853	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HDDIGPKE_01854	2.83e-299	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	Gluconate
HDDIGPKE_01855	2.68e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDDIGPKE_01856	6.23e-123	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01858	7.85e-72	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HDDIGPKE_01859	3.75e-200	yabE	-	-	S	-	-	-	G5 domain
HDDIGPKE_01860	0.0	-	-	-	N	-	-	-	domain, Protein
HDDIGPKE_01861	7.17e-29	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDDIGPKE_01862	5.4e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDDIGPKE_01863	8.07e-174	-	-	-	U	-	-	-	domain, Protein
HDDIGPKE_01864	9.35e-97	-	5.1.1.1	-	K	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	helix_turn _helix lactose operon repressor
HDDIGPKE_01865	1.38e-205	malQ_1	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HDDIGPKE_01866	8.22e-213	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01867	8.61e-89	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HDDIGPKE_01868	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HDDIGPKE_01869	1.58e-301	-	-	-	S	-	-	-	YbbR-like protein
HDDIGPKE_01870	1.11e-206	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDDIGPKE_01871	1.09e-271	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HDDIGPKE_01872	3.59e-150	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDDIGPKE_01873	4.71e-31	-	-	-	K	-	-	-	AraC-like ligand binding domain
HDDIGPKE_01874	5.03e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDDIGPKE_01875	5.25e-279	-	-	-	-	-	-	-	-
HDDIGPKE_01876	9.86e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01877	6.05e-96	-	-	-	-	-	-	-	-
HDDIGPKE_01879	2.18e-216	-	-	-	GK	-	-	-	ROK family
HDDIGPKE_01881	1.46e-249	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDDIGPKE_01882	3.2e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
HDDIGPKE_01883	9.26e-227	-	-	-	-	-	-	-	-
HDDIGPKE_01884	1.52e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDDIGPKE_01885	2.5e-131	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HDDIGPKE_01886	1.5e-61	rcoM2	-	-	KT	ko:K02477,ko:K21696	-	ko00000,ko02022,ko03000	phosphorelay signal transduction system
HDDIGPKE_01887	1.99e-236	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HDDIGPKE_01888	9.87e-159	-	-	-	S	-	-	-	IA, variant 3
HDDIGPKE_01889	4.96e-253	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_01890	4.51e-197	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
HDDIGPKE_01891	2.83e-116	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
HDDIGPKE_01892	9.88e-41	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01893	2.14e-59	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDDIGPKE_01894	4.05e-143	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDDIGPKE_01895	3.64e-140	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDDIGPKE_01897	7.34e-140	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDDIGPKE_01898	7.94e-54	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HDDIGPKE_01899	5.71e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HDDIGPKE_01900	8.65e-81	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HDDIGPKE_01902	3.7e-71	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HDDIGPKE_01903	7.8e-11	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_01904	1.02e-203	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDDIGPKE_01905	2.8e-198	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HDDIGPKE_01906	1.95e-06	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HDDIGPKE_01907	1.33e-123	-	-	-	K	-	-	-	Acetyltransferase GNAT family
HDDIGPKE_01908	7.76e-181	yoaP	-	-	E	-	-	-	YoaP-like
HDDIGPKE_01909	1.23e-47	-	-	-	S	-	-	-	RNHCP domain
HDDIGPKE_01910	3.63e-270	-	-	-	T	-	-	-	Response regulator receiver domain protein
HDDIGPKE_01911	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
HDDIGPKE_01912	1.07e-68	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDDIGPKE_01913	1.66e-138	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDDIGPKE_01914	2.79e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDDIGPKE_01915	1.9e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDDIGPKE_01916	6.25e-33	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HDDIGPKE_01917	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HDDIGPKE_01918	4.1e-241	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain protein
HDDIGPKE_01920	2.65e-95	-	3.1.3.41	-	G	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDDIGPKE_01921	9.71e-39	-	-	-	K	-	-	-	Putative zinc ribbon domain
HDDIGPKE_01922	4.58e-50	tig_1	-	-	O	ko:K03545	-	ko00000	peptidylprolyl isomerase
HDDIGPKE_01923	3.52e-96	-	-	-	K	-	-	-	Transcriptional regulator
HDDIGPKE_01924	4.6e-220	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDDIGPKE_01925	1.29e-101	-	-	-	KT	-	-	-	Response regulator of the LytR AlgR family
HDDIGPKE_01926	2.57e-292	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDDIGPKE_01927	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDDIGPKE_01928	1.55e-229	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HDDIGPKE_01929	1.22e-288	-	-	-	-	-	-	-	-
HDDIGPKE_01930	0.0	-	-	-	M	-	-	-	Diguanylate cyclase, GGDEF domain
HDDIGPKE_01931	2.42e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDDIGPKE_01932	1.55e-86	-	-	-	K	ko:K03086,ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HDDIGPKE_01933	1.21e-85	-	-	-	K	-	-	-	Cupin domain
HDDIGPKE_01934	1.92e-240	-	-	-	M	-	-	-	Bacterial extracellular solute-binding protein, family 7
HDDIGPKE_01935	2.83e-110	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HDDIGPKE_01936	7.94e-290	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01937	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HDDIGPKE_01938	2.37e-271	-	-	-	G	-	-	-	Major Facilitator Superfamily
HDDIGPKE_01939	6.52e-148	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDDIGPKE_01942	4.13e-51	-	-	-	-	-	-	-	-
HDDIGPKE_01943	1.36e-256	-	-	-	K	-	-	-	AraC-like ligand binding domain
HDDIGPKE_01944	0.0	-	-	-	G	ko:K03292	-	ko00000	Transporter, major facilitator family protein
HDDIGPKE_01945	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HDDIGPKE_01948	1e-62	-	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDDIGPKE_01949	2.88e-185	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
HDDIGPKE_01950	4.62e-182	tcyN	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Amino acid ABC transporter ATP-binding protein, PAAT family
HDDIGPKE_01951	9.26e-149	-	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid ABC transporter
HDDIGPKE_01952	5.48e-206	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDDIGPKE_01953	5.66e-168	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01954	8.19e-121	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase small
HDDIGPKE_01955	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
HDDIGPKE_01956	1.62e-277	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HDDIGPKE_01957	4.36e-72	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HDDIGPKE_01958	5.68e-128	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDDIGPKE_01959	2.84e-214	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_01960	9.26e-309	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HDDIGPKE_01965	1.01e-113	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01966	1.54e-100	-	-	-	M	-	-	-	glycosyl transferase group 1
HDDIGPKE_01967	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDDIGPKE_01968	1.64e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDDIGPKE_01970	6.28e-87	-	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDDIGPKE_01971	2.73e-182	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDDIGPKE_01972	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HDDIGPKE_01973	2.14e-184	aroD	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HDDIGPKE_01974	0.0	-	-	-	C	-	-	-	NADH oxidase
HDDIGPKE_01975	6.8e-93	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HDDIGPKE_01976	8.23e-291	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01977	1.5e-128	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HDDIGPKE_01979	1.31e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HDDIGPKE_01981	2.94e-165	-	-	-	K	-	-	-	transcriptional regulator AraC family
HDDIGPKE_01982	3.02e-294	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_01983	4.6e-214	scrK	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_01984	6.87e-120	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDDIGPKE_01985	4.63e-195	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HDDIGPKE_01986	1.58e-81	-	-	-	G	-	-	-	Aldolase
HDDIGPKE_01987	1.04e-286	-	-	-	P	-	-	-	arsenite transmembrane transporter activity
HDDIGPKE_01988	0.0	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01989	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HDDIGPKE_01990	5.69e-65	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HDDIGPKE_01991	2.15e-116	nfrA2	-	-	C	-	-	-	Nitroreductase family
HDDIGPKE_01992	7.94e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDDIGPKE_01993	2.36e-61	-	-	-	S	-	-	-	Trp repressor protein
HDDIGPKE_01994	2.36e-118	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HDDIGPKE_01995	8.13e-186	-	-	-	Q	-	-	-	FAH family
HDDIGPKE_01996	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HDDIGPKE_01997	5.49e-149	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDDIGPKE_01998	2.13e-157	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDDIGPKE_01999	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDDIGPKE_02000	1.38e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HDDIGPKE_02001	4.82e-183	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDDIGPKE_02002	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDDIGPKE_02003	1.63e-206	cobW	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
HDDIGPKE_02004	4.83e-266	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HDDIGPKE_02005	1.95e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDDIGPKE_02007	4.17e-147	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDDIGPKE_02008	1.02e-314	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDDIGPKE_02009	1.22e-282	-	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HDDIGPKE_02010	2.78e-112	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_02011	1.06e-116	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDDIGPKE_02012	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HDDIGPKE_02013	8.68e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HDDIGPKE_02014	6.74e-218	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
HDDIGPKE_02015	8.74e-194	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
HDDIGPKE_02016	6.59e-52	-	-	-	-	-	-	-	-
HDDIGPKE_02017	2.23e-65	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HDDIGPKE_02021	1.44e-62	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HDDIGPKE_02022	1.49e-97	-	-	-	K	-	-	-	Transcriptional regulator
HDDIGPKE_02023	4.6e-220	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDDIGPKE_02024	1.2e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HDDIGPKE_02025	2.83e-151	-	-	-	G	-	-	-	Ribose Galactose Isomerase
HDDIGPKE_02026	2.16e-83	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HDDIGPKE_02027	6.89e-190	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Psort location Cytoplasmic, score
HDDIGPKE_02028	2.97e-25	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDDIGPKE_02030	1.88e-187	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HDDIGPKE_02031	8.35e-224	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDDIGPKE_02032	2.82e-83	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDDIGPKE_02033	1.6e-171	-	-	-	E	-	-	-	Pyridoxal-phosphate dependent protein
HDDIGPKE_02035	5.26e-58	-	-	-	S	-	-	-	TSCPD domain
HDDIGPKE_02036	1.72e-199	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
HDDIGPKE_02037	1.02e-102	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HDDIGPKE_02038	7.73e-231	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDDIGPKE_02039	1.43e-223	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
HDDIGPKE_02040	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDDIGPKE_02041	4.79e-39	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
HDDIGPKE_02042	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HDDIGPKE_02043	6.63e-163	resD	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HDDIGPKE_02044	2.19e-15	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDDIGPKE_02045	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDDIGPKE_02046	6.83e-69	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
HDDIGPKE_02047	1.41e-50	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDDIGPKE_02048	6.31e-295	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HDDIGPKE_02049	3.34e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDDIGPKE_02051	8.41e-114	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HDDIGPKE_02052	1.58e-238	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
HDDIGPKE_02053	1.93e-55	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HDDIGPKE_02054	2.52e-168	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDDIGPKE_02055	1.47e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
HDDIGPKE_02056	1.04e-177	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDIGPKE_02057	2.43e-167	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDDIGPKE_02058	8.71e-43	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons