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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HHKAHHOL_00001	1.34e-08	-	-	-	-	-	-	-	-
HHKAHHOL_00002	1.45e-107	FcbC	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HHKAHHOL_00003	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	creatinase
HHKAHHOL_00004	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHKAHHOL_00005	7.5e-132	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHKAHHOL_00006	0.0	ftsA	-	-	D	-	-	-	cell division protein FtsA
HHKAHHOL_00007	3.18e-193	yycJ	-	-	J	-	-	-	Metallo-beta-lactamase domain protein
HHKAHHOL_00008	1.58e-96	-	-	-	-	-	-	-	-
HHKAHHOL_00009	2.14e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HHKAHHOL_00010	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HHKAHHOL_00011	1.51e-295	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHKAHHOL_00012	2.7e-171	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
HHKAHHOL_00013	2.88e-294	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HHKAHHOL_00014	0.0	-	-	-	E	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HHKAHHOL_00015	2.91e-257	-	-	-	S	-	-	-	YibE F family protein
HHKAHHOL_00016	2.55e-304	-	-	-	S	-	-	-	Belongs to the UPF0348 family
HHKAHHOL_00017	1.68e-182	-	3.4.22.70	-	U	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HHKAHHOL_00018	1.15e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHKAHHOL_00019	2.24e-123	-	-	-	S	ko:K07040	-	ko00000	acr, cog1399
HHKAHHOL_00020	5.07e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HHKAHHOL_00021	7.29e-266	-	-	-	V	-	-	-	antibiotic catabolic process
HHKAHHOL_00022	2.1e-194	-	1.6.5.3, 3.4.21.107	-	O	ko:K00337,ko:K04771	ko00190,ko01100,ko01503,ko02020,map00190,map01100,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine-type endopeptidase activity
HHKAHHOL_00023	1.87e-159	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HHKAHHOL_00024	8.11e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHKAHHOL_00025	3.3e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHKAHHOL_00026	2.7e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHKAHHOL_00027	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HHKAHHOL_00028	8.84e-216	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHKAHHOL_00029	2.25e-283	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHKAHHOL_00030	2.25e-301	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HHKAHHOL_00032	6.44e-72	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHKAHHOL_00033	1.33e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHKAHHOL_00034	1.07e-52	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HHKAHHOL_00035	2.44e-40	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HHKAHHOL_00036	7.8e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHKAHHOL_00037	0.0	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HHKAHHOL_00038	8.07e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHKAHHOL_00039	3.34e-132	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHKAHHOL_00040	8.76e-201	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHKAHHOL_00041	1.95e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHKAHHOL_00042	0.0	-	-	-	S	-	-	-	Flagellar hook-length control protein FliK
HHKAHHOL_00043	3.41e-65	flhB1	-	-	S	ko:K04061	-	ko00000,ko02044	cytoplasmic domain of flagellar protein FhlB
HHKAHHOL_00044	7.68e-84	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HHKAHHOL_00045	1.42e-216	yfiH	-	-	L	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HHKAHHOL_00046	1.05e-250	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HHKAHHOL_00047	1.03e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HHKAHHOL_00048	7.95e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_00049	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00050	1.68e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HHKAHHOL_00051	2.49e-149	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHKAHHOL_00052	8.35e-232	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HHKAHHOL_00053	1.55e-104	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Psort location Cytoplasmic, score
HHKAHHOL_00054	2.25e-264	ugpC_1	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHKAHHOL_00055	1.55e-252	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HHKAHHOL_00056	0.0	-	-	-	CNT	-	-	-	Iron only hydrogenase large subunit, C-terminal domain
HHKAHHOL_00057	0.0	parE	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit
HHKAHHOL_00058	0.0	gyrA_1	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit
HHKAHHOL_00059	3.96e-154	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00060	1.22e-178	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HHKAHHOL_00062	1.83e-234	-	-	-	M	ko:K03699	-	ko00000,ko02042	Cbs domain
HHKAHHOL_00063	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	'glutamate synthase
HHKAHHOL_00064	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	'glutamate synthase
HHKAHHOL_00065	2.41e-187	-	-	-	-	-	-	-	-
HHKAHHOL_00066	6.4e-187	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HHKAHHOL_00067	0.0	-	-	-	E	-	-	-	oligoendopeptidase, M3 family
HHKAHHOL_00069	8.69e-187	-	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	homoserine dehydrogenase
HHKAHHOL_00070	1.8e-145	-	-	-	V	-	-	-	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHKAHHOL_00071	1.2e-121	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00072	4.79e-222	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
HHKAHHOL_00073	3.67e-275	maeB	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HHKAHHOL_00074	7.54e-301	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHKAHHOL_00075	6.32e-46	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
HHKAHHOL_00076	7.76e-187	prmC	-	-	J	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00077	3.18e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHKAHHOL_00078	7.32e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHKAHHOL_00079	1.81e-141	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	xylanase chitin deacetylase
HHKAHHOL_00080	2.04e-208	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00081	5.26e-99	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
HHKAHHOL_00082	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHKAHHOL_00083	2.02e-248	kfoC_2	-	-	M	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00084	6.56e-287	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HHKAHHOL_00085	5.25e-279	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HHKAHHOL_00086	6.63e-277	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	PFAM aminotransferase class I and II
HHKAHHOL_00087	7.39e-184	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HHKAHHOL_00088	9.24e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHKAHHOL_00089	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HHKAHHOL_00090	3.34e-297	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	PDZ DHR GLGF domain protein
HHKAHHOL_00091	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_00092	4.84e-230	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	PFAM Glycosyl transferase family 2
HHKAHHOL_00093	1.21e-244	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HHKAHHOL_00094	3.78e-242	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HHKAHHOL_00095	0.0	-	2.7.8.6	-	M	ko:K00996	-	ko00000,ko01000,ko01005	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HHKAHHOL_00096	7.44e-231	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HHKAHHOL_00097	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HHKAHHOL_00098	2.87e-43	-	-	-	-	-	-	-	-
HHKAHHOL_00099	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HHKAHHOL_00100	2.67e-220	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HHKAHHOL_00101	1.61e-309	-	-	-	KT	-	-	-	COG4219 Antirepressor regulating drug resistance
HHKAHHOL_00102	5.1e-89	-	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
HHKAHHOL_00103	2.17e-278	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	PFAM Nucleotidyl transferase
HHKAHHOL_00104	1.57e-231	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HHKAHHOL_00105	1.81e-250	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HHKAHHOL_00106	2.38e-152	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_00107	1.66e-72	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00108	1.04e-171	-	-	-	M	-	-	-	Glycosyl transferase family 2
HHKAHHOL_00109	6.46e-139	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00110	6.31e-128	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00111	9.68e-118	-	-	-	G	-	-	-	Acyltransferase family
HHKAHHOL_00112	9.21e-297	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HHKAHHOL_00113	9.17e-127	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyltransferase 26 family
HHKAHHOL_00114	1.65e-92	-	-	-	-	-	-	-	-
HHKAHHOL_00115	6.05e-269	-	-	-	V	-	-	-	ABC transporter transmembrane region
HHKAHHOL_00116	5.91e-116	-	-	-	S	-	-	-	Glycosyl transferase family 11
HHKAHHOL_00117	2.98e-202	-	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HHKAHHOL_00118	4.24e-46	-	-	-	S	-	-	-	Glycosyl transferase family 8
HHKAHHOL_00120	8.39e-45	-	-	-	S	-	-	-	Acyltransferase family
HHKAHHOL_00121	4.98e-133	-	-	-	-	-	-	-	-
HHKAHHOL_00123	1.01e-68	-	2.3.1.209	-	E	ko:K21379	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HHKAHHOL_00124	6.85e-134	-	-	-	Q	-	-	-	HAD-superfamily phosphatase, subfamily IIIC
HHKAHHOL_00125	5.53e-17	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HHKAHHOL_00126	5.01e-223	-	-	-	D	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HHKAHHOL_00127	3.26e-190	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	PFAM Glycosyl transferase family 2
HHKAHHOL_00128	2.41e-31	-	-	-	S	-	-	-	Acyltransferase family
HHKAHHOL_00131	6.04e-148	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHKAHHOL_00132	2.26e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00133	6.37e-07	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00134	9.34e-76	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
HHKAHHOL_00136	4.44e-225	-	-	-	O	-	-	-	Restriction endonuclease
HHKAHHOL_00137	6.86e-40	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HHKAHHOL_00138	9.6e-152	-	-	-	L	-	-	-	Integrase core domain
HHKAHHOL_00139	4.44e-18	-	-	-	-	-	-	-	-
HHKAHHOL_00140	4.4e-83	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HHKAHHOL_00141	6.68e-203	-	-	-	L	ko:K06400	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_00142	1.53e-47	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HHKAHHOL_00143	2.38e-99	-	-	-	-	-	-	-	-
HHKAHHOL_00144	7.66e-51	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HHKAHHOL_00145	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHKAHHOL_00146	0.0	cstA	-	-	T	ko:K06200	-	ko00000	carbon starvation protein CstA
HHKAHHOL_00147	1.57e-156	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
HHKAHHOL_00148	7.77e-277	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HHKAHHOL_00149	2.02e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain protein
HHKAHHOL_00150	1.74e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HHKAHHOL_00151	2.34e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HHKAHHOL_00152	1.48e-219	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HHKAHHOL_00153	8.65e-175	-	-	-	H	ko:K22132	-	ko00000,ko03016	Thif family
HHKAHHOL_00154	1.4e-283	ttcA	-	-	H	-	-	-	Belongs to the TtcA family
HHKAHHOL_00155	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Family 5
HHKAHHOL_00156	3.75e-221	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_00157	9.14e-204	-	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport
HHKAHHOL_00158	8.55e-225	-	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHKAHHOL_00159	2.86e-140	-	-	-	EP	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport system ATPase
HHKAHHOL_00160	7.31e-24	-	-	-	-	-	-	-	-
HHKAHHOL_00161	3.26e-256	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HHKAHHOL_00162	1.65e-122	-	-	-	S	-	-	-	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family
HHKAHHOL_00163	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HHKAHHOL_00164	2.67e-165	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HHKAHHOL_00168	4.85e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHKAHHOL_00169	6.53e-168	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00170	2.68e-240	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00171	4.39e-192	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHKAHHOL_00172	1.62e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHKAHHOL_00173	3.3e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HHKAHHOL_00174	3.51e-14	glnQ2	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HHKAHHOL_00175	7.8e-207	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00176	3.81e-104	yncA	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase GNAT family
HHKAHHOL_00177	2.32e-210	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mg2 transporter protein
HHKAHHOL_00178	2.1e-245	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HHKAHHOL_00179	4.95e-257	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00180	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_00181	4.46e-148	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HHKAHHOL_00182	8.34e-38	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHKAHHOL_00183	8.29e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHKAHHOL_00184	2.09e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHKAHHOL_00185	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHKAHHOL_00186	1.52e-207	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHKAHHOL_00187	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHKAHHOL_00188	5.68e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HHKAHHOL_00189	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase family 79, N-terminal domain
HHKAHHOL_00190	1.08e-220	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score
HHKAHHOL_00191	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HHKAHHOL_00192	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HHKAHHOL_00193	0.0	-	-	-	D	-	-	-	membrane
HHKAHHOL_00194	2.75e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HHKAHHOL_00195	7.71e-157	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHKAHHOL_00196	4.85e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HHKAHHOL_00197	1.92e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHKAHHOL_00198	2.73e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHKAHHOL_00199	1.77e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHKAHHOL_00200	2.78e-85	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHKAHHOL_00201	4.33e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHKAHHOL_00202	1.61e-102	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHKAHHOL_00203	1.15e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HHKAHHOL_00204	2.02e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHKAHHOL_00205	8.55e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHKAHHOL_00206	3e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHKAHHOL_00207	9.39e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHKAHHOL_00208	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHKAHHOL_00209	4.95e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHKAHHOL_00210	1.62e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHKAHHOL_00211	4.24e-78	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHKAHHOL_00212	2.83e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHKAHHOL_00213	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HHKAHHOL_00214	1.48e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HHKAHHOL_00215	4.1e-308	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHKAHHOL_00216	1.06e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHKAHHOL_00217	1.17e-187	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HHKAHHOL_00218	3.01e-23	-	-	-	-	-	-	-	-
HHKAHHOL_00219	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHKAHHOL_00220	4.24e-78	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHKAHHOL_00221	9.17e-46	-	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HHKAHHOL_00222	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HHKAHHOL_00223	2.78e-309	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHKAHHOL_00224	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00225	0.0	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHKAHHOL_00226	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHKAHHOL_00227	2.38e-66	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00228	1.03e-266	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00229	0.0	-	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HHKAHHOL_00230	7.59e-151	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00231	6.13e-231	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHKAHHOL_00232	1.15e-128	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHKAHHOL_00233	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
HHKAHHOL_00234	1.89e-253	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HHKAHHOL_00235	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHKAHHOL_00236	2.08e-118	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHKAHHOL_00237	1.83e-31	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHKAHHOL_00238	1.32e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HHKAHHOL_00239	6.52e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HHKAHHOL_00240	3.36e-62	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body complex protein FliE
HHKAHHOL_00241	2.45e-225	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HHKAHHOL_00242	1.17e-226	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	Flagellar motor switch protein flig
HHKAHHOL_00243	1.77e-124	-	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar assembly protein FliH
HHKAHHOL_00244	2.39e-311	fliI	3.6.3.14	-	NU	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	Flagellar protein export ATPase FliI
HHKAHHOL_00245	1.31e-88	fliJ	-	-	NOU	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	flagellar export protein FliJ
HHKAHHOL_00246	8.27e-175	-	-	-	-	-	-	-	-
HHKAHHOL_00247	3.2e-297	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HHKAHHOL_00248	9.25e-179	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Required for flagellar hook formation. May act as a scaffolding protein
HHKAHHOL_00249	1.94e-81	flg	-	-	N	-	-	-	TIGRFAM flagellar operon protein
HHKAHHOL_00250	0.0	flgE	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	basal body rod protein
HHKAHHOL_00251	7.78e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	PFAM MotA TolQ ExbB proton channel
HHKAHHOL_00252	9.45e-209	-	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	PFAM OmpA MotB domain protein
HHKAHHOL_00253	1.88e-112	-	-	-	S	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HHKAHHOL_00254	2.2e-226	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	flagellar motor switch protein FliM
HHKAHHOL_00255	1.52e-225	fliN	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar motor switch protein flin
HHKAHHOL_00256	1.38e-77	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator receiver
HHKAHHOL_00257	5.8e-83	-	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HHKAHHOL_00258	3.97e-183	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HHKAHHOL_00259	4.64e-53	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliQ
HHKAHHOL_00260	3.77e-173	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	flagellar biosynthetic protein FliR
HHKAHHOL_00261	2.7e-258	flhB	-	-	N	ko:K02401,ko:K13820	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHKAHHOL_00262	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHKAHHOL_00263	1.61e-292	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	PFAM GTP-binding signal recognition particle SRP54 G- domain
HHKAHHOL_00264	2.48e-176	flhG	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HHKAHHOL_00265	6.31e-172	-	-	-	M	-	-	-	Flagellar protein YcgR
HHKAHHOL_00266	1.83e-243	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HHKAHHOL_00267	0.0	cheA	2.7.13.3	-	T	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	Signal transducing histidine kinase homodimeric
HHKAHHOL_00268	5.12e-96	-	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	PFAM CheW domain protein
HHKAHHOL_00269	6.15e-139	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	Chemotaxis protein CheC, inhibitor of MCP methylation
HHKAHHOL_00270	2.11e-108	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HHKAHHOL_00271	6.49e-55	-	-	-	-	-	-	-	-
HHKAHHOL_00272	2.36e-169	fliA	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHKAHHOL_00273	1.98e-65	-	-	-	-	-	-	-	-
HHKAHHOL_00274	2.34e-111	-	-	-	M	-	-	-	Membrane
HHKAHHOL_00275	3.85e-116	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHKAHHOL_00276	8.97e-170	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HHKAHHOL_00277	4.68e-209	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHKAHHOL_00278	1.89e-166	-	-	-	E	-	-	-	Belongs to the P(II) protein family
HHKAHHOL_00279	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00280	9.65e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHKAHHOL_00282	7.86e-222	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
HHKAHHOL_00283	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HHKAHHOL_00284	6.52e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHKAHHOL_00285	1.97e-130	-	-	-	-	-	-	-	-
HHKAHHOL_00286	1.6e-224	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHKAHHOL_00287	3.96e-181	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HHKAHHOL_00288	3.61e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00289	2.81e-233	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHKAHHOL_00290	3.58e-238	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHKAHHOL_00291	3.74e-150	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HHKAHHOL_00292	5.51e-244	-	-	-	MT	-	-	-	Cell Wall Hydrolase
HHKAHHOL_00294	4.45e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHKAHHOL_00295	2.23e-97	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	PFAM Histidine triad (HIT) protein
HHKAHHOL_00296	1.1e-120	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HHKAHHOL_00297	6.42e-237	-	-	-	I	-	-	-	SCP-2 sterol transfer family
HHKAHHOL_00298	3.91e-268	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	PFAM Rhomboid family
HHKAHHOL_00299	2.54e-274	-	-	-	T	-	-	-	(FHA) domain
HHKAHHOL_00300	0.000161	-	-	-	-	-	-	-	-
HHKAHHOL_00301	6.86e-98	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HHKAHHOL_00302	2.06e-169	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00303	0.0	-	-	-	S	-	-	-	Psort location
HHKAHHOL_00304	5.41e-28	-	-	-	S	-	-	-	Putative Flagellin, Flp1-like, domain
HHKAHHOL_00305	2.74e-303	-	-	-	NU	ko:K12511	-	ko00000,ko02044	Psort location CytoplasmicMembrane, score
HHKAHHOL_00306	2.28e-167	tadB	-	-	U	ko:K12510	-	ko00000,ko02044	Psort location CytoplasmicMembrane, score
HHKAHHOL_00307	6.03e-289	ptlH	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HHKAHHOL_00308	1.01e-252	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00309	1.94e-90	-	3.4.23.43	-	S	ko:K02278	-	ko00000,ko01000,ko02035,ko02044	Type IV leader peptidase family
HHKAHHOL_00310	7.27e-56	-	-	-	S	ko:K06317	-	ko00000	SigmaK-factor processing regulatory protein BofA
HHKAHHOL_00311	7.71e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HHKAHHOL_00312	8.67e-111	-	-	-	NOU	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar protein FliS
HHKAHHOL_00313	0.0	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHKAHHOL_00314	2.2e-42	-	-	-	D	-	-	-	cluster protein-associated redox disulfide domain
HHKAHHOL_00315	6.57e-190	mecB	-	-	NOT	ko:K16511	-	ko00000	Negative regulator of genetic competence
HHKAHHOL_00317	1.85e-263	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHKAHHOL_00318	3.16e-170	-	-	-	-	-	-	-	-
HHKAHHOL_00319	2.07e-20	-	-	-	-	-	-	-	-
HHKAHHOL_00320	0.0	ydhD	-	-	M	-	-	-	family 18
HHKAHHOL_00321	3.51e-155	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-Acetylmuramoyl-L-alanine amidase
HHKAHHOL_00322	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_00323	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HHKAHHOL_00324	0.0	SpoVK	-	-	O	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00325	3.98e-295	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00326	2.57e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HHKAHHOL_00327	0.0	ybhJ	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HHKAHHOL_00328	4.17e-157	-	-	-	G	-	-	-	IA, variant 3
HHKAHHOL_00329	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00330	1.05e-160	phoP_1	-	-	KT	-	-	-	response regulator receiver
HHKAHHOL_00331	2.27e-231	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HHKAHHOL_00332	4.25e-65	-	-	-	K	-	-	-	helix-turn-helix
HHKAHHOL_00334	0.0	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_00335	7.23e-201	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_00336	1.92e-165	-	-	-	-	-	-	-	-
HHKAHHOL_00337	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHKAHHOL_00338	1.03e-206	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00339	2.96e-285	-	-	-	T	ko:K07814	-	ko00000,ko02022	metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00340	1.09e-271	-	-	-	T	-	-	-	HD domain
HHKAHHOL_00341	2.13e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00342	0.0	cydD	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	Abc transporter
HHKAHHOL_00343	0.0	cydC	-	-	V	ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HHKAHHOL_00345	0.0	-	-	-	S	-	-	-	associated with various cellular activities
HHKAHHOL_00346	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00347	0.0	tetP	-	-	J	-	-	-	Elongation factor
HHKAHHOL_00348	9.08e-53	-	-	-	-	-	-	-	-
HHKAHHOL_00350	1.26e-05	-	-	-	-	-	-	-	-
HHKAHHOL_00351	4.04e-259	-	-	-	C	-	-	-	Iron only hydrogenase large subunit, C-terminal domain
HHKAHHOL_00352	0.0	-	-	-	J	-	-	-	NOL1 NOP2 sun family
HHKAHHOL_00353	1.65e-145	-	-	-	-	-	-	-	-
HHKAHHOL_00354	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00355	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HHKAHHOL_00356	7.6e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HHKAHHOL_00357	4.48e-215	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HHKAHHOL_00358	1.89e-167	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HHKAHHOL_00359	1.02e-82	-	-	-	-	-	-	-	-
HHKAHHOL_00360	7.15e-179	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00361	1.01e-162	rnhA	3.1.26.4	-	L	ko:K03469,ko:K06993	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HHKAHHOL_00362	3.28e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_00363	0.0	-	-	-	G	-	-	-	Alpha galactosidase A
HHKAHHOL_00364	0.0	araB	-	-	G	-	-	-	Carbohydrate kinase, FGGY family protein
HHKAHHOL_00365	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HHKAHHOL_00366	3.69e-150	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHKAHHOL_00367	2.74e-205	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HHKAHHOL_00368	2.66e-220	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase
HHKAHHOL_00369	3.06e-174	ulaF	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ribulose-5-phosphate 4-epimerase
HHKAHHOL_00370	2.4e-257	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HHKAHHOL_00371	3.35e-77	-	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HHKAHHOL_00372	1.77e-257	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HHKAHHOL_00373	3.13e-228	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_00374	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00375	0.0	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HHKAHHOL_00376	1.86e-205	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HHKAHHOL_00377	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation
HHKAHHOL_00378	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HHKAHHOL_00379	1.91e-143	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HHKAHHOL_00380	3.35e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00381	0.0	-	-	-	S	ko:K07137	-	ko00000	'oxidoreductase
HHKAHHOL_00382	3.41e-226	-	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHKAHHOL_00383	1.84e-316	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_00384	5.9e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHKAHHOL_00385	0.0	yfmM	-	-	S	ko:K06158	-	ko00000,ko03012	Abc transporter
HHKAHHOL_00386	2.81e-279	-	-	-	S	ko:K18475	-	ko00000,ko01000,ko02035	PFAM Uncharacterised protein family (UPF0153)
HHKAHHOL_00387	4.76e-36	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00388	2.1e-142	-	1.1.1.219	-	M	ko:K00091	-	ko00000,ko01000	NAD dependent epimerase dehydratase family
HHKAHHOL_00389	1.56e-28	-	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_00390	6.78e-27	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_00391	1.63e-214	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHKAHHOL_00392	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 2, TIM barrel domain
HHKAHHOL_00393	7.6e-153	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_00394	3.3e-19	-	-	-	-	-	-	-	-
HHKAHHOL_00395	1.82e-234	-	-	-	G	-	-	-	MFS/sugar transport protein
HHKAHHOL_00397	2.24e-139	effD	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_00398	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HHKAHHOL_00399	0.0	-	-	-	G	-	-	-	Fibronectin type III-like domain
HHKAHHOL_00400	1.55e-155	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHKAHHOL_00401	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4982)
HHKAHHOL_00402	1.98e-157	-	1.1.1.100, 1.1.1.30	-	IQ	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HHKAHHOL_00403	9.01e-88	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HHKAHHOL_00404	1.55e-15	-	-	-	L	ko:K03502	-	ko00000,ko03400	Nucleotidyltransferase DNA polymerase involved in DNA repair
HHKAHHOL_00407	1.56e-115	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_00408	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HHKAHHOL_00409	5.9e-249	-	-	-	L	-	-	-	PFAM Transposase DDE domain
HHKAHHOL_00410	2.54e-251	ytvI	-	-	D	-	-	-	Sporulation integral membrane protein YtvI
HHKAHHOL_00411	1.56e-258	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HHKAHHOL_00412	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glutaminyl-tRNA synthetase
HHKAHHOL_00413	6.66e-200	-	-	-	S	ko:K09766	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2225)
HHKAHHOL_00414	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	aminotransferase class I and II
HHKAHHOL_00415	1.21e-306	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHKAHHOL_00416	5.47e-260	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHKAHHOL_00417	3.28e-110	RimI	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase, gnat family
HHKAHHOL_00418	1.01e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHKAHHOL_00419	1.16e-212	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHKAHHOL_00420	7.07e-293	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	PFAM Aminotransferase class-III
HHKAHHOL_00421	1.75e-276	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HHKAHHOL_00422	9.84e-160	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	TIGRFAM Competence protein ComEA, helix-hairpin-helix
HHKAHHOL_00423	1.1e-162	-	-	-	T	-	-	-	response regulator receiver
HHKAHHOL_00424	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_00425	6.15e-234	-	-	-	S	ko:K06298	-	ko00000	Sporulation and spore germination
HHKAHHOL_00426	0.0	-	-	-	M	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HHKAHHOL_00427	1.65e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III (delta' subunit)
HHKAHHOL_00428	3.45e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HHKAHHOL_00429	9.38e-219	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHKAHHOL_00430	6.55e-261	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HHKAHHOL_00431	5.59e-128	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
HHKAHHOL_00432	3.89e-14	-	-	-	K	-	-	-	Transcriptional regulator
HHKAHHOL_00433	4.43e-99	-	-	-	-	-	-	-	-
HHKAHHOL_00434	5.72e-103	-	-	-	-	-	-	-	-
HHKAHHOL_00435	3.67e-122	-	-	-	-	-	-	-	-
HHKAHHOL_00436	4.25e-39	-	-	-	-	-	-	-	-
HHKAHHOL_00437	2.78e-160	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHKAHHOL_00438	4.47e-296	-	-	-	Q	-	-	-	amidohydrolase
HHKAHHOL_00440	1.91e-172	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00441	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HHKAHHOL_00442	2.44e-207	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00443	2.51e-279	-	-	-	M	-	-	-	Efflux transporter, RND family, MFP subunit
HHKAHHOL_00444	1.68e-163	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_00445	5.34e-304	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC-type antimicrobial peptide transport system, permease component
HHKAHHOL_00446	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HHKAHHOL_00447	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HHKAHHOL_00448	2.83e-238	-	-	-	K	-	-	-	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_00449	2.84e-283	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHKAHHOL_00450	0.0	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_00451	2.81e-196	-	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_00452	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_00453	2.21e-50	-	-	-	-	-	-	-	-
HHKAHHOL_00454	1.57e-235	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_00455	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HHKAHHOL_00456	8.8e-284	-	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HHKAHHOL_00457	2.91e-68	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHKAHHOL_00458	2.13e-132	-	-	-	S	-	-	-	BAAT / Acyl-CoA thioester hydrolase C terminal
HHKAHHOL_00459	3.85e-90	-	-	-	V	-	-	-	ABC transporter
HHKAHHOL_00460	2.8e-97	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HHKAHHOL_00461	1.15e-34	-	-	-	C	-	-	-	Flavodoxin
HHKAHHOL_00462	2.21e-137	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HHKAHHOL_00463	3.13e-135	-	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
HHKAHHOL_00464	7.63e-224	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HHKAHHOL_00465	3.19e-285	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHKAHHOL_00466	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
HHKAHHOL_00467	3.79e-291	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HHKAHHOL_00468	4.83e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHKAHHOL_00469	4.54e-210	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HHKAHHOL_00470	4.55e-64	-	-	-	S	-	-	-	protein, YerC YecD
HHKAHHOL_00471	3.06e-143	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00472	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHKAHHOL_00473	1.36e-28	-	-	-	-	-	-	-	-
HHKAHHOL_00474	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHKAHHOL_00475	8.09e-46	-	-	-	-	-	-	-	-
HHKAHHOL_00476	2.04e-217	-	-	-	K	-	-	-	LysR substrate binding domain
HHKAHHOL_00477	3.72e-124	-	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HHKAHHOL_00478	1.8e-124	-	-	-	P	ko:K07240	-	ko00000,ko02000	CytoplasmicMembrane, score 9.99
HHKAHHOL_00479	2.45e-49	-	-	-	-	-	-	-	-
HHKAHHOL_00480	8.7e-123	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHKAHHOL_00481	2.5e-163	srrA_2	-	-	KT	-	-	-	response regulator receiver
HHKAHHOL_00482	0.0	yycG_1	-	-	T	-	-	-	Histidine kinase- DNA gyrase B
HHKAHHOL_00483	5.1e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHKAHHOL_00484	4.29e-254	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00486	5.2e-156	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00487	2.34e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the EPSP synthase family. MurA subfamily
HHKAHHOL_00488	0.0	-	-	-	M	-	-	-	Peptidase, M23
HHKAHHOL_00489	2.34e-113	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHKAHHOL_00490	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHKAHHOL_00491	1.09e-250	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HHKAHHOL_00493	1.98e-118	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHKAHHOL_00494	0.0	-	-	-	J	ko:K01163	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_00495	3.96e-49	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00497	3.56e-184	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHKAHHOL_00498	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Glycine radical
HHKAHHOL_00499	2.1e-218	-	-	-	T	-	-	-	PAS fold
HHKAHHOL_00500	2.6e-233	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHKAHHOL_00502	1.1e-132	-	-	-	I	-	-	-	Hydrolase, nudix family
HHKAHHOL_00503	1.96e-306	-	-	-	M	-	-	-	cellulase activity
HHKAHHOL_00504	1.02e-81	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00505	1.31e-61	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00506	2.76e-99	ohrR	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00507	3.19e-83	-	1.11.1.9	-	C	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HHKAHHOL_00508	3.47e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	belongs to the thioredoxin family
HHKAHHOL_00509	4.02e-203	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHKAHHOL_00510	5.57e-95	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HHKAHHOL_00511	2.2e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HHKAHHOL_00512	2.49e-100	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHKAHHOL_00513	2.91e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHKAHHOL_00514	9.98e-179	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHKAHHOL_00515	7.57e-210	ecfA2	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHKAHHOL_00516	2.62e-203	ecfA2	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHKAHHOL_00517	8.74e-123	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHKAHHOL_00518	5.52e-286	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	PFAM aminotransferase class I and II
HHKAHHOL_00519	6.86e-108	Lrp	-	-	K	-	-	-	transcriptional regulator, AsnC family
HHKAHHOL_00520	2.78e-225	hypE	-	-	O	ko:K04655	-	ko00000	PFAM AIR synthase related protein
HHKAHHOL_00521	0.0	-	-	-	V	ko:K18346	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	PFAM VanW family protein
HHKAHHOL_00523	1.11e-90	-	-	-	-	-	-	-	-
HHKAHHOL_00524	4.25e-165	-	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	'dna polymerase iii
HHKAHHOL_00525	0.0	-	1.21.98.3	-	C	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Radical SAM domain protein
HHKAHHOL_00526	3.25e-252	-	-	-	T	-	-	-	TIGRFAM Diguanylate cyclase
HHKAHHOL_00527	1.72e-129	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HHKAHHOL_00528	1.83e-229	-	-	-	J	ko:K01421	-	ko00000	Psort location Cellwall, score
HHKAHHOL_00529	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00530	3.79e-131	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00531	9.8e-259	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00532	1.03e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00533	0.0	-	-	-	T	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00534	7.98e-62	-	-	-	S	-	-	-	DJ-1/PfpI family
HHKAHHOL_00535	9.74e-110	-	-	-	C	-	-	-	Flavodoxin domain
HHKAHHOL_00536	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HHKAHHOL_00537	1.87e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHKAHHOL_00538	1.89e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional regulator DeoR family
HHKAHHOL_00539	2.24e-139	-	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	phosphoglycerate mutase
HHKAHHOL_00540	9.89e-86	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HHKAHHOL_00541	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHKAHHOL_00542	1.74e-192	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHKAHHOL_00543	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHKAHHOL_00544	7.04e-127	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHKAHHOL_00545	1.28e-81	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHKAHHOL_00546	2.58e-41	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHKAHHOL_00547	3.02e-172	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HHKAHHOL_00548	6.36e-92	-	-	-	-	-	-	-	-
HHKAHHOL_00549	7.13e-52	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HHKAHHOL_00550	2.57e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	cytidine and deoxycytidylate deaminase zinc-binding region
HHKAHHOL_00551	3.31e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHKAHHOL_00552	2.32e-94	ywlE	3.1.3.48, 3.9.1.2, 5.3.1.6	-	T	ko:K01104,ko:K01808,ko:K20201	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHKAHHOL_00553	1.74e-251	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHKAHHOL_00554	6.16e-263	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HHKAHHOL_00555	3.06e-141	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HHKAHHOL_00556	5.16e-72	-	-	-	C	-	-	-	flavodoxin
HHKAHHOL_00557	1.11e-281	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHKAHHOL_00558	2.18e-91	adhR	-	-	K	-	-	-	Transcriptional regulator
HHKAHHOL_00559	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHKAHHOL_00560	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHKAHHOL_00561	1.1e-313	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HHKAHHOL_00562	2.27e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HHKAHHOL_00563	0.0	yybT	-	-	T	-	-	-	domain protein
HHKAHHOL_00564	3.58e-152	-	-	-	O	-	-	-	Heat shock protein
HHKAHHOL_00565	1.06e-57	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHKAHHOL_00566	3.34e-101	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHKAHHOL_00567	1.55e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HHKAHHOL_00568	7.29e-41	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00569	1.98e-175	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HHKAHHOL_00571	5.46e-115	spmB	-	-	S	ko:K06374	-	ko00000	PFAM nucleoside recognition domain protein
HHKAHHOL_00572	0.0	-	-	-	T	-	-	-	GGDEF domain
HHKAHHOL_00573	1.07e-141	spmA	-	-	S	ko:K06373	-	ko00000	membrane protein required for spore maturation
HHKAHHOL_00574	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
HHKAHHOL_00575	6.68e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHKAHHOL_00576	2.23e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHKAHHOL_00577	4.47e-175	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
HHKAHHOL_00578	9.03e-203	yaaT	-	-	K	-	-	-	domain protein
HHKAHHOL_00579	1.52e-240	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	'dna polymerase iii
HHKAHHOL_00580	1.08e-96	-	-	-	S	ko:K09770	-	ko00000	Protein of unknown function (DUF327)
HHKAHHOL_00581	1.07e-134	gmk_1	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00582	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HHKAHHOL_00583	1.65e-144	mobA	2.7.7.77	-	H	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdenum cofactor guanylyltransferase activity
HHKAHHOL_00584	1.61e-221	-	-	-	-	-	-	-	-
HHKAHHOL_00585	4.52e-147	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HHKAHHOL_00586	3.45e-116	-	-	-	-	-	-	-	-
HHKAHHOL_00587	0.0	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHKAHHOL_00588	3.45e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHKAHHOL_00589	3.34e-295	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00591	1.13e-253	-	-	-	I	ko:K01066	-	ko00000,ko01000	Hydrolase, alpha beta domain protein
HHKAHHOL_00592	4.75e-314	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HHKAHHOL_00593	0.0	-	6.2.1.3, 6.2.1.48, 6.2.1.8	-	IQ	ko:K01897,ko:K02182,ko:K22133	ko00061,ko00071,ko00630,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00630,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II
HHKAHHOL_00594	1.64e-209	-	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HHKAHHOL_00595	2.26e-167	-	-	-	C	ko:K03521	-	ko00000	electron transfer flavoprotein
HHKAHHOL_00596	5.28e-286	-	-	-	C	-	-	-	formyl-CoA transferase activity
HHKAHHOL_00597	3.27e-297	-	-	-	C	-	-	-	CoA-transferase family III
HHKAHHOL_00598	8.16e-154	-	-	-	P	-	-	-	domain protein
HHKAHHOL_00599	2.05e-181	-	4.2.1.149	-	I	ko:K08299	-	ko00000,ko01000	overlaps another CDS with the same product name
HHKAHHOL_00600	2.85e-290	-	1.3.8.13	-	C	ko:K08297	-	ko00000,ko01000	acyl-CoA dehydrogenase
HHKAHHOL_00601	1.89e-187	etfB	-	-	C	ko:K03521	-	ko00000	electron transfer flavoprotein
HHKAHHOL_00602	2.84e-239	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	electron transfer flavoprotein
HHKAHHOL_00603	3.63e-270	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HHKAHHOL_00605	0.0	-	-	-	E	ko:K14392	-	ko00000,ko02000	symporter activity
HHKAHHOL_00606	1.78e-285	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_00607	1.22e-113	-	-	-	K	-	-	-	transcriptional
HHKAHHOL_00608	6.86e-61	-	-	-	S	-	-	-	branched-chain amino acid transport protein
HHKAHHOL_00609	2.73e-123	-	-	-	E	-	-	-	branched-chain amino acid permease (azaleucine resistance)
HHKAHHOL_00610	2.65e-107	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00611	6.64e-82	TdcF	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HHKAHHOL_00612	1.61e-295	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HHKAHHOL_00613	2.7e-197	-	-	-	E	-	-	-	amidohydrolase
HHKAHHOL_00614	4.94e-109	-	-	-	K	-	-	-	MarR family
HHKAHHOL_00615	3.15e-80	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HHKAHHOL_00616	2.02e-43	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00617	6.39e-158	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	Hydrogenase accessory protein HypB
HHKAHHOL_00618	0.0	-	-	-	C	-	-	-	'glutamate synthase
HHKAHHOL_00619	2.08e-81	-	-	-	S	ko:K04651	-	ko00000,ko03110	Zn finger protein HypA HybF (Possibly regulating hydrogenase expression)
HHKAHHOL_00620	2.25e-285	-	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	PFAM peptidase M14 carboxypeptidase A
HHKAHHOL_00621	1.78e-217	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
HHKAHHOL_00622	4.43e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00623	6.51e-156	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00625	4.28e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HHKAHHOL_00626	2.34e-47	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HHKAHHOL_00627	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF4173)
HHKAHHOL_00628	1.34e-235	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HHKAHHOL_00629	3.51e-292	-	-	-	C	-	-	-	Alcohol dehydrogenase class IV
HHKAHHOL_00630	0.0	-	1.12.7.2	-	C	ko:K00533	-	ko00000,ko01000	Iron only hydrogenase large subunit, C-terminal domain
HHKAHHOL_00631	3.16e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHKAHHOL_00632	1.21e-266	-	-	-	H	-	-	-	Protein of unknown function (DUF2974)
HHKAHHOL_00633	7.18e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHKAHHOL_00634	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHKAHHOL_00635	1.15e-80	-	-	-	F	-	-	-	NUDIX domain
HHKAHHOL_00636	2.38e-233	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_00637	4.32e-110	mgsA	2.7.1.24, 4.2.3.3	-	G	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	ko00000,ko00001,ko00002,ko01000	methylglyoxal synthase
HHKAHHOL_00638	9.81e-201	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHKAHHOL_00639	4.46e-310	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_00640	2.08e-210	-	-	-	K	-	-	-	lysR substrate binding domain
HHKAHHOL_00641	7.23e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHKAHHOL_00642	4.38e-146	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant 3
HHKAHHOL_00643	1.9e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
HHKAHHOL_00644	2.23e-260	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHKAHHOL_00645	3.65e-140	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HHKAHHOL_00646	1.62e-307	rny	-	-	M	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HHKAHHOL_00647	5.03e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Hydrolase, nudix family
HHKAHHOL_00649	6.96e-207	xerC	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HHKAHHOL_00650	9.11e-253	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHKAHHOL_00651	3.82e-180	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHKAHHOL_00652	2.11e-108	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHKAHHOL_00653	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Abc transporter
HHKAHHOL_00654	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHKAHHOL_00655	0.0	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHKAHHOL_00656	6.43e-286	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HHKAHHOL_00658	5.66e-262	-	-	-	T	-	-	-	Bacterial SH3 domain homologues
HHKAHHOL_00659	1.83e-182	rluF	5.4.99.21, 5.4.99.22	-	J	ko:K06178,ko:K06182	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHKAHHOL_00660	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHKAHHOL_00661	3.28e-229	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHKAHHOL_00662	1.72e-90	-	-	-	-	-	-	-	-
HHKAHHOL_00663	3.19e-79	asp	-	-	S	-	-	-	protein conserved in bacteria
HHKAHHOL_00664	2.03e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHKAHHOL_00665	1.07e-282	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHKAHHOL_00666	4.36e-39	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHKAHHOL_00667	3.84e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHKAHHOL_00668	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHKAHHOL_00669	3.81e-170	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HHKAHHOL_00670	1.16e-207	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHKAHHOL_00671	9.88e-95	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHKAHHOL_00672	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HHKAHHOL_00673	8.61e-281	spoIVB	3.4.21.116	-	T	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HHKAHHOL_00674	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_00675	3.27e-186	spo0A	-	-	NT	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HHKAHHOL_00677	0.0	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00678	1.04e-218	-	-	-	-	-	-	-	-
HHKAHHOL_00679	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_00680	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Psort location Cytoplasmic, score
HHKAHHOL_00681	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Psort location CytoplasmicMembrane, score
HHKAHHOL_00682	4.42e-50	-	-	-	-	-	-	-	-
HHKAHHOL_00683	5.42e-294	-	-	-	M	-	-	-	glycosyl transferase group 1
HHKAHHOL_00684	1.6e-177	-	-	-	S	-	-	-	group 2 family protein
HHKAHHOL_00685	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4874)
HHKAHHOL_00686	4.42e-275	-	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HHKAHHOL_00687	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00688	8.52e-287	-	-	-	S	-	-	-	Uncharacterised nucleotidyltransferase
HHKAHHOL_00689	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_00690	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4874)
HHKAHHOL_00692	7.04e-83	-	-	-	-	-	-	-	-
HHKAHHOL_00693	1.3e-82	-	-	-	-	-	-	-	-
HHKAHHOL_00694	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HHKAHHOL_00695	3.32e-84	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HHKAHHOL_00696	4.13e-109	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00697	0.0	-	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HHKAHHOL_00698	9.23e-214	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00699	4.27e-251	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, solute-binding protein
HHKAHHOL_00700	1.85e-106	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Abc transporter, permease protein
HHKAHHOL_00701	1.71e-12	potC	-	-	E	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_00702	2.29e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HHKAHHOL_00703	2.27e-219	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHKAHHOL_00705	1.24e-248	tmpC	-	-	S	ko:K07335	-	ko00000	basic membrane
HHKAHHOL_00706	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	Abc transporter
HHKAHHOL_00707	2.57e-251	-	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00708	3.27e-205	-	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00709	1.1e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHKAHHOL_00710	3.45e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HHKAHHOL_00711	1.48e-291	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHKAHHOL_00712	2.98e-24	-	-	-	-	-	-	-	-
HHKAHHOL_00713	9.27e-122	-	-	-	T	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00714	7.02e-288	-	-	-	S	-	-	-	Protein conserved in bacteria
HHKAHHOL_00715	3.04e-154	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHKAHHOL_00716	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HHKAHHOL_00717	5.53e-266	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHKAHHOL_00718	0.0	-	-	-	S	ko:K06921	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_00719	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHKAHHOL_00720	0.0	-	-	-	NT	-	-	-	PilZ domain
HHKAHHOL_00721	5.91e-158	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	glucosamine-1-phosphate N-acetyltransferase activity
HHKAHHOL_00722	3.72e-196	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00723	6.87e-295	-	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_00724	3.27e-41	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HHKAHHOL_00725	2.23e-111	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HHKAHHOL_00726	3.33e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF3837)
HHKAHHOL_00727	6.09e-92	-	-	-	S	ko:K06404	-	ko00000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00728	1.06e-149	spoVAA	-	-	S	ko:K06403	-	ko00000	COG NOG11305 non supervised orthologous group
HHKAHHOL_00730	4.28e-179	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00731	6.2e-98	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00732	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	Abc transporter
HHKAHHOL_00733	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HHKAHHOL_00734	6.88e-160	spoT	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HHKAHHOL_00735	1.06e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00736	2.89e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHKAHHOL_00737	5.25e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHKAHHOL_00738	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, alpha subunit
HHKAHHOL_00740	1.72e-40	-	-	-	-	-	-	-	-
HHKAHHOL_00741	2.34e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
HHKAHHOL_00742	2.13e-279	malL	3.2.1.1, 3.2.1.10	GH13	G	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	ko00000,ko00001,ko01000	PFAM alpha amylase, catalytic
HHKAHHOL_00743	4.92e-104	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHKAHHOL_00744	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHKAHHOL_00745	1.73e-246	-	-	-	G	ko:K02058	-	ko00000,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_00746	1.43e-228	yjfF	-	-	G	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00747	3.96e-234	-	-	-	G	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00748	0.0	araG_1	3.6.3.17	-	G	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	import. Responsible for energy coupling to the transport system
HHKAHHOL_00749	2.83e-244	-	-	-	G	ko:K02058	-	ko00000,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_00750	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_00751	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HHKAHHOL_00752	1.23e-12	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00753	3.36e-34	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHKAHHOL_00754	0.0	bbmA	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HHKAHHOL_00755	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00756	0.0	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_00757	0.0	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHKAHHOL_00758	1.09e-66	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Protein conserved in bacteria
HHKAHHOL_00759	1.97e-53	-	-	-	S	-	-	-	COG NOG21970 non supervised orthologous group
HHKAHHOL_00760	2.9e-93	-	-	-	C	-	-	-	flavodoxin
HHKAHHOL_00762	9.95e-150	-	-	-	-	-	-	-	-
HHKAHHOL_00764	6.06e-222	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	radical SAM domain protein
HHKAHHOL_00765	2.91e-295	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HHKAHHOL_00766	4.15e-231	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00767	5.85e-149	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00768	0.0	-	-	-	I	-	-	-	Psort location
HHKAHHOL_00769	1.95e-158	pdhR	-	-	K	ko:K05799	-	ko00000,ko03000	FCD domain
HHKAHHOL_00770	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HHKAHHOL_00771	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Abc transporter
HHKAHHOL_00772	2.49e-198	-	-	-	S	ko:K08974	-	ko00000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00773	2.57e-270	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis
HHKAHHOL_00774	0.0	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HHKAHHOL_00775	2.74e-144	cmk	-	-	F	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00776	2.85e-98	-	-	-	-	-	-	-	-
HHKAHHOL_00777	2.99e-288	hydF	-	-	S	-	-	-	Hydrogenase maturation GTPase HydF
HHKAHHOL_00778	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	biosynthesis protein ThiH
HHKAHHOL_00779	3.79e-260	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
HHKAHHOL_00780	4.19e-50	-	-	-	K	-	-	-	Iron-only hydrogenase system regulator
HHKAHHOL_00782	1.06e-258	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HHKAHHOL_00783	6.34e-272	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
HHKAHHOL_00784	0.0	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	delta-lactam-biosynthetic de-N-acetylase
HHKAHHOL_00785	4.49e-298	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HHKAHHOL_00786	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHKAHHOL_00787	3.19e-88	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00788	6.89e-97	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00789	4.24e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00790	5.6e-103	nifU	-	-	C	ko:K04488	-	ko00000	assembly protein, NifU family
HHKAHHOL_00791	1.77e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HHKAHHOL_00792	2.8e-214	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	PFAM Aminotransferase class-III
HHKAHHOL_00793	6.74e-68	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	PFAM Aminotransferase class-III
HHKAHHOL_00794	1.5e-151	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HHKAHHOL_00795	1.1e-111	cysT	-	-	O	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_00796	5.2e-20	cysT	-	-	O	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_00797	1.4e-158	-	-	-	F	-	-	-	Hydrolase, nudix family
HHKAHHOL_00798	1.79e-10	nimA	-	-	S	ko:K07005	-	ko00000	resistance protein
HHKAHHOL_00799	1.92e-220	-	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00800	0.0	-	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	import. Responsible for energy coupling to the transport system
HHKAHHOL_00801	2.43e-245	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system, periplasmic
HHKAHHOL_00802	4.47e-229	-	-	-	G	-	-	-	TIM barrel
HHKAHHOL_00803	3.33e-250	-	-	-	S	-	-	-	domain protein
HHKAHHOL_00804	5.07e-236	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HHKAHHOL_00805	7.19e-155	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
HHKAHHOL_00806	1.86e-213	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM Extracellular solute-binding protein, family 3
HHKAHHOL_00807	2.77e-172	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHKAHHOL_00808	1.67e-150	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	acid ABC transporter
HHKAHHOL_00809	3.64e-142	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HHKAHHOL_00810	1.9e-23	-	-	-	-	-	-	-	-
HHKAHHOL_00811	2.45e-20	-	-	-	V	-	-	-	HNH nucleases
HHKAHHOL_00812	6.78e-160	-	-	-	KLT	-	-	-	Protein kinase domain
HHKAHHOL_00813	1.51e-170	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
HHKAHHOL_00815	3.36e-57	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHKAHHOL_00817	1.99e-49	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00818	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate transporter
HHKAHHOL_00819	1.07e-99	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00821	8.24e-78	-	-	-	C	-	-	-	Flavodoxin
HHKAHHOL_00822	5.04e-128	-	-	-	S	-	-	-	Cupin domain
HHKAHHOL_00823	1.11e-45	-	-	-	-	-	-	-	-
HHKAHHOL_00824	2.31e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00825	0.0	GcvP	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_00826	7.66e-52	-	-	-	G	ko:K11189	-	ko00000,ko02000	Phosphocarrier protein (Hpr)
HHKAHHOL_00827	5.99e-41	-	-	-	-	-	-	-	-
HHKAHHOL_00828	1.64e-284	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHKAHHOL_00829	1.24e-232	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
HHKAHHOL_00830	1.89e-255	dnaD	-	-	L	-	-	-	DnaD domain protein
HHKAHHOL_00832	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HHKAHHOL_00833	3.63e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HHKAHHOL_00834	2.22e-256	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase GlgD subunit
HHKAHHOL_00835	7.45e-54	spoVG	-	-	D	ko:K06412	-	ko00000	Could be involved in septation
HHKAHHOL_00836	1.01e-174	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHKAHHOL_00837	3.91e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHKAHHOL_00838	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHKAHHOL_00839	1.81e-231	-	5.2.1.8	-	-	ko:K07533	-	ko00000,ko01000,ko03110	-
HHKAHHOL_00840	2.05e-174	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HHKAHHOL_00841	1.23e-95	-	-	-	S	-	-	-	PrcB C-terminal
HHKAHHOL_00842	6.73e-51	veg	-	-	S	-	-	-	Protein conserved in bacteria
HHKAHHOL_00843	0.0	-	-	-	M	-	-	-	LysM domain
HHKAHHOL_00844	1.21e-264	-	-	-	-	-	-	-	-
HHKAHHOL_00845	9.68e-208	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC p60 family
HHKAHHOL_00846	1.21e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HHKAHHOL_00847	3.4e-146	-	-	-	-	-	-	-	-
HHKAHHOL_00848	1.88e-223	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HHKAHHOL_00849	6.43e-85	-	-	-	-	-	-	-	-
HHKAHHOL_00850	1.11e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHKAHHOL_00851	3.31e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHKAHHOL_00853	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_00854	5.33e-79	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HHKAHHOL_00855	3.23e-13	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
HHKAHHOL_00858	1.41e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HHKAHHOL_00859	9.21e-68	-	-	-	-	-	-	-	-
HHKAHHOL_00861	3.18e-69	-	-	-	-	-	-	-	-
HHKAHHOL_00862	1.46e-208	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_00863	3.72e-241	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport
HHKAHHOL_00864	8.83e-242	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHKAHHOL_00865	5.64e-255	appF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHKAHHOL_00866	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Family 5
HHKAHHOL_00867	1.22e-129	-	-	-	-	-	-	-	-
HHKAHHOL_00868	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HHKAHHOL_00869	2.02e-223	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_00870	0.0	-	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport
HHKAHHOL_00871	2.34e-284	appD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHKAHHOL_00872	6.04e-249	appF	-	-	P	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHKAHHOL_00874	2.3e-261	braC	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	PFAM Extracellular ligand-binding receptor
HHKAHHOL_00875	6.95e-186	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00876	5.02e-75	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00877	2.1e-101	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00878	1.54e-238	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_00879	2.39e-177	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Abc transporter
HHKAHHOL_00880	3.94e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Abc transporter
HHKAHHOL_00881	5.73e-149	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00882	0.0	pepF	-	-	E	-	-	-	Oligoendopeptidase, pepF M3 family
HHKAHHOL_00883	1.76e-280	-	-	-	C	ko:K07079	-	ko00000	aldo keto reductase
HHKAHHOL_00884	2.65e-248	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HHKAHHOL_00885	5.68e-117	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHKAHHOL_00886	1.78e-285	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00887	3.68e-107	-	-	-	S	-	-	-	YcxB-like protein
HHKAHHOL_00888	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00889	5.02e-189	-	-	-	KT	-	-	-	response regulator
HHKAHHOL_00890	1.22e-214	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHKAHHOL_00891	8.7e-81	-	-	-	S	-	-	-	Cupin domain
HHKAHHOL_00892	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHKAHHOL_00894	3.03e-134	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00895	4.56e-287	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00896	3.73e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00897	1.88e-125	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HHKAHHOL_00898	0.0	-	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHKAHHOL_00899	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	family 43
HHKAHHOL_00900	2.17e-246	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
HHKAHHOL_00901	5.98e-50	-	-	-	-	-	-	-	-
HHKAHHOL_00903	2.59e-230	-	-	-	K	-	-	-	regulatory protein, arsR
HHKAHHOL_00904	3.3e-262	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_00905	3.17e-301	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	peptidase U32
HHKAHHOL_00906	5.05e-146	yrrM	-	-	S	-	-	-	O-methyltransferase
HHKAHHOL_00907	1.32e-76	-	-	-	S	ko:K07082	-	ko00000	YceG-like family
HHKAHHOL_00908	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHKAHHOL_00909	1.66e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00910	9.19e-91	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHKAHHOL_00911	8.74e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HHKAHHOL_00912	2.5e-314	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	MiaB-like tRNA modifying enzyme
HHKAHHOL_00913	6.69e-47	-	-	-	G	-	-	-	phosphocarrier protein HPr
HHKAHHOL_00914	8.17e-286	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHKAHHOL_00915	1.31e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HHKAHHOL_00916	3.51e-173	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHKAHHOL_00917	1.29e-235	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HHKAHHOL_00918	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHKAHHOL_00919	0.0	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_00920	1.39e-179	-	-	-	-	-	-	-	-
HHKAHHOL_00921	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHKAHHOL_00922	8.66e-70	azlD	-	-	E	-	-	-	branched-chain amino acid
HHKAHHOL_00923	2.21e-177	-	-	-	E	-	-	-	branched-chain amino acid permease (azaleucine resistance)
HHKAHHOL_00924	2.77e-137	yjbJ	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	transglycosylase
HHKAHHOL_00925	6.11e-106	-	-	-	K	-	-	-	MarR family
HHKAHHOL_00926	5.16e-217	aguB	3.5.1.53, 3.5.1.6	-	S	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000	N-carbamoylputrescine amidase
HHKAHHOL_00927	1.44e-284	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
HHKAHHOL_00928	1.18e-296	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
HHKAHHOL_00929	2.08e-303	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HHKAHHOL_00930	2.81e-214	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HHKAHHOL_00931	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HHKAHHOL_00932	5.11e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHKAHHOL_00933	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HHKAHHOL_00934	6.57e-178	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHKAHHOL_00935	4.7e-206	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHKAHHOL_00936	1.11e-147	ssb1	-	-	L	-	-	-	PFAM single-strand binding protein Primosomal replication protein n
HHKAHHOL_00937	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HHKAHHOL_00938	0.0	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain
HHKAHHOL_00939	1.55e-253	-	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	COG0739 Membrane proteins related to metalloendopeptidases
HHKAHHOL_00940	6.2e-98	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HHKAHHOL_00941	2.74e-183	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score
HHKAHHOL_00942	8.04e-230	-	-	-	-	-	-	-	-
HHKAHHOL_00943	0.0	-	-	-	M	-	-	-	Membrane protein involved in D-alanine export
HHKAHHOL_00944	9.11e-304	dapL	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HHKAHHOL_00945	7.69e-123	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
HHKAHHOL_00946	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HHKAHHOL_00947	1.04e-184	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the HisA HisF family
HHKAHHOL_00948	4.62e-38	-	-	-	L	-	-	-	PFAM Transposase DDE domain
HHKAHHOL_00949	1.11e-125	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HHKAHHOL_00950	7.1e-111	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHKAHHOL_00951	1.02e-65	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00952	6.55e-55	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00953	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHKAHHOL_00954	1.01e-161	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HHKAHHOL_00955	0.0	-	1.1.5.3	-	P	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HHKAHHOL_00956	2.12e-312	-	-	-	C	-	-	-	pyridine nucleotide-disulfide oxidoreductase
HHKAHHOL_00957	1.55e-79	-	-	-	S	-	-	-	protein with conserved CXXC pairs
HHKAHHOL_00958	1.95e-134	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_00959	2.28e-127	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	glycerol-3-phosphate responsive antiterminator
HHKAHHOL_00960	6.71e-52	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00961	3.61e-212	-	-	-	S	-	-	-	SseB protein N-terminal domain
HHKAHHOL_00962	2.52e-305	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00963	1.83e-264	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_00964	1.69e-295	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_00965	1.88e-192	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HHKAHHOL_00966	0.0	-	3.2.1.1, 3.2.1.10	GH13	G	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase catalytic
HHKAHHOL_00967	8.24e-217	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHKAHHOL_00968	1.58e-204	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_00969	9.99e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HHKAHHOL_00970	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	PFAM Mannitol dehydrogenase
HHKAHHOL_00971	2.79e-275	-	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Monogalactosyldiacylglycerol synthase
HHKAHHOL_00972	2.52e-141	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the PlsY family
HHKAHHOL_00973	3.87e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHKAHHOL_00974	5.85e-293	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00975	7.51e-189	-	-	-	S	-	-	-	NOG26512 non supervised orthologous group
HHKAHHOL_00976	3.36e-163	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_00977	2.23e-203	-	-	-	K	-	-	-	lysR substrate binding domain
HHKAHHOL_00978	1.43e-26	-	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHKAHHOL_00979	4.86e-264	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_00980	8.78e-238	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HHKAHHOL_00983	5.5e-190	yoaP	-	-	E	-	-	-	YoaP-like
HHKAHHOL_00984	1.84e-169	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_00985	7.67e-222	-	-	-	K	-	-	-	HTH domain
HHKAHHOL_00986	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHKAHHOL_00987	3.78e-173	-	-	-	V	-	-	-	Abi-like protein
HHKAHHOL_00988	1.28e-21	-	-	-	L	ko:K07491	-	ko00000	PFAM Transposase
HHKAHHOL_00989	8.36e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
HHKAHHOL_00990	8.37e-61	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HHKAHHOL_00992	9.2e-215	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHKAHHOL_00993	4.6e-124	-	-	-	-	-	-	-	-
HHKAHHOL_00994	7.12e-42	-	-	-	-	-	-	-	-
HHKAHHOL_00995	8.98e-129	-	-	-	K	-	-	-	Acetyltransferase GNAT family
HHKAHHOL_00996	3.78e-306	-	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_00997	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Abc transporter
HHKAHHOL_00998	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HHKAHHOL_00999	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01000	3.93e-291	-	-	-	S	ko:K07335	-	ko00000	ABC-type transport system, periplasmic component surface lipoprotein
HHKAHHOL_01001	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	heavy metal translocating P-type ATPase
HHKAHHOL_01002	3.32e-54	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
HHKAHHOL_01003	7.65e-101	iscU	-	-	C	ko:K04488	-	ko00000	assembly protein, NifU family
HHKAHHOL_01004	8.24e-290	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Cysteine desulfurase
HHKAHHOL_01005	2.39e-255	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	SufB sufD domain protein
HHKAHHOL_01006	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	feS assembly protein SufB
HHKAHHOL_01007	6.08e-178	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HHKAHHOL_01008	2.13e-44	-	-	-	-	-	-	-	-
HHKAHHOL_01009	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HHKAHHOL_01010	1.99e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHKAHHOL_01011	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase domain protein
HHKAHHOL_01012	2.29e-186	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_01013	4.86e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_01014	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HHKAHHOL_01015	3.83e-127	-	-	-	C	-	-	-	Rubredoxin-type Fe(Cys)4 protein
HHKAHHOL_01016	8.16e-301	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHKAHHOL_01017	9.25e-305	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHKAHHOL_01018	1.77e-295	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HHKAHHOL_01019	2.78e-132	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_01020	7.2e-56	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HHKAHHOL_01021	2.82e-189	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01022	2.56e-176	gufA	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HHKAHHOL_01023	3.31e-149	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01024	2.97e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHKAHHOL_01025	3.82e-156	-	-	-	-	-	-	-	-
HHKAHHOL_01026	4.07e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHKAHHOL_01028	1e-305	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HHKAHHOL_01029	1.87e-22	-	-	-	S	-	-	-	YabP family
HHKAHHOL_01030	1.02e-296	yqfD	-	-	S	ko:K06438	-	ko00000	Sporulation protein YqfD
HHKAHHOL_01031	1.08e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HHKAHHOL_01032	3.03e-276	-	-	-	O	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HHKAHHOL_01033	7.3e-116	ybeY	3.5.4.5	-	F	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHKAHHOL_01034	0.0	spoVB1	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
HHKAHHOL_01036	8.66e-316	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HHKAHHOL_01037	0.0	-	-	-	H	ko:K07137	-	ko00000	'oxidoreductase
HHKAHHOL_01038	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHKAHHOL_01039	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHKAHHOL_01040	4.46e-227	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHKAHHOL_01041	1.83e-315	ynbB	-	-	P	-	-	-	aluminum resistance protein
HHKAHHOL_01042	4.83e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HHKAHHOL_01043	7.53e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HHKAHHOL_01044	2.13e-176	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HHKAHHOL_01045	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HHKAHHOL_01046	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HHKAHHOL_01047	2.57e-149	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHKAHHOL_01048	4.33e-192	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HHKAHHOL_01049	1.01e-39	minE	-	-	D	ko:K03608	-	ko00000,ko03036,ko04812	regulation of division septum assembly
HHKAHHOL_01050	1.18e-243	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HHKAHHOL_01051	1.32e-92	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HHKAHHOL_01052	7.17e-233	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHKAHHOL_01053	1.56e-93	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01054	5.79e-43	-	-	-	S	ko:K09779	-	ko00000	Conserved protein
HHKAHHOL_01055	0.0	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHKAHHOL_01056	3.8e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHKAHHOL_01057	1.92e-107	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHKAHHOL_01058	1.1e-181	-	-	-	S	-	-	-	S4 domain protein
HHKAHHOL_01059	1.05e-250	aroB	2.7.1.71, 4.2.3.4	-	E	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHKAHHOL_01060	3.94e-122	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHKAHHOL_01061	8.32e-226	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHKAHHOL_01062	4.71e-149	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_01063	1.6e-81	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHKAHHOL_01064	1.21e-275	dacB2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHKAHHOL_01065	0.0	-	-	-	I	-	-	-	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHKAHHOL_01066	3.53e-160	-	-	-	P	-	-	-	decarboxylase gamma
HHKAHHOL_01067	5.5e-60	gcdC	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HHKAHHOL_01068	1.57e-261	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	decarboxylase beta subunit
HHKAHHOL_01069	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	carboxylase
HHKAHHOL_01070	8e-117	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHKAHHOL_01071	1.65e-213	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HHKAHHOL_01072	3.13e-293	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HHKAHHOL_01073	3.98e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HHKAHHOL_01074	9.52e-204	ispH	1.17.7.4	-	IM	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHKAHHOL_01075	7.41e-255	ispH	1.17.7.4	-	J	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHKAHHOL_01076	1.9e-187	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	PFAM MCP methyltransferase, CheR-type
HHKAHHOL_01077	5.48e-269	-	-	-	L	ko:K07502	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_01078	3.12e-315	rnfC	-	-	C	ko:K03615	-	ko00000	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily
HHKAHHOL_01079	5.46e-210	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HHKAHHOL_01080	7.21e-136	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HHKAHHOL_01081	3.61e-157	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HHKAHHOL_01082	1.06e-126	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HHKAHHOL_01083	5.13e-173	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
HHKAHHOL_01084	9.86e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHKAHHOL_01085	2.06e-198	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHKAHHOL_01086	1.55e-42	ynzC	-	-	S	-	-	-	UPF0291 protein
HHKAHHOL_01087	1.45e-150	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHKAHHOL_01088	1.02e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHKAHHOL_01089	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HHKAHHOL_01090	7.44e-84	-	-	-	S	-	-	-	NusG domain II
HHKAHHOL_01091	1.13e-102	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HHKAHHOL_01092	6.4e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHKAHHOL_01093	4.65e-231	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHKAHHOL_01094	6.75e-91	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHKAHHOL_01095	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	peptidase U32
HHKAHHOL_01096	2.71e-316	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHKAHHOL_01097	0.0	pbpA2	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	Penicillin-binding Protein
HHKAHHOL_01098	7.56e-108	apfA	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
HHKAHHOL_01099	1.5e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01100	1.81e-208	-	-	-	S	-	-	-	Psort location
HHKAHHOL_01101	3.2e-95	-	-	-	S	-	-	-	Sporulation protein YtfJ
HHKAHHOL_01103	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, solute-binding protein
HHKAHHOL_01104	2.91e-192	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Abc transporter, permease protein
HHKAHHOL_01105	4.69e-203	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	sugar transport system permease
HHKAHHOL_01106	1.36e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_01107	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HHKAHHOL_01108	2.23e-228	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HHKAHHOL_01109	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HHKAHHOL_01111	9.03e-215	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01112	6.88e-122	-	-	-	-	-	-	-	-
HHKAHHOL_01113	4.01e-146	-	-	-	S	-	-	-	Membrane
HHKAHHOL_01114	3.05e-196	punA	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHKAHHOL_01115	0.0	mtaD	3.5.4.28, 3.5.4.31, 3.5.4.40	-	F	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHKAHHOL_01116	5.09e-192	folD4	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01117	9.24e-06	-	-	-	-	-	-	-	-
HHKAHHOL_01118	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHKAHHOL_01119	8.67e-203	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	transmembrane signaling receptor activity
HHKAHHOL_01120	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HHKAHHOL_01121	7.82e-154	-	-	-	C	-	-	-	PFAM Uncharacterised ACR, YkgG family COG1556
HHKAHHOL_01122	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHKAHHOL_01124	5.84e-220	cobW	-	-	K	-	-	-	CobW P47K family protein
HHKAHHOL_01125	7.15e-230	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01126	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01127	1.52e-245	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HHKAHHOL_01128	3.99e-211	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_01129	2.69e-192	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_01130	1.8e-217	pyrK_1	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	PFAM oxidoreductase FAD NAD(P)-binding domain protein
HHKAHHOL_01131	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	'glutamate synthase
HHKAHHOL_01132	2.98e-169	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01133	2.13e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_01134	3.51e-19	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HHKAHHOL_01135	2.03e-232	-	-	-	Q	-	-	-	AMP-binding enzyme
HHKAHHOL_01136	2.35e-169	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHKAHHOL_01137	5.81e-25	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HHKAHHOL_01138	3.57e-265	-	-	-	M	-	-	-	MBOAT, membrane-bound O-acyltransferase family
HHKAHHOL_01139	1.84e-122	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HHKAHHOL_01140	2.1e-139	-	-	-	K	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HHKAHHOL_01141	5.62e-159	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHKAHHOL_01143	8.09e-221	-	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HHKAHHOL_01144	5.2e-247	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHKAHHOL_01145	1.02e-157	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_01146	2.09e-153	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system, permease component
HHKAHHOL_01147	8.42e-151	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.97
HHKAHHOL_01148	1.28e-193	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01149	6.99e-284	-	-	-	G	ko:K09955	-	ko00000	protein conserved in bacteria
HHKAHHOL_01150	1.15e-201	-	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	LD-carboxypeptidase
HHKAHHOL_01151	1.22e-191	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01153	1.66e-266	-	-	-	V	-	-	-	proteins homologs of microcin C7 resistance protein MccF
HHKAHHOL_01154	1.64e-125	-	-	-	-	-	-	-	-
HHKAHHOL_01155	2.04e-105	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01156	1.91e-198	-	-	-	S	-	-	-	Phospholipase, patatin family
HHKAHHOL_01157	1.73e-220	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase
HHKAHHOL_01158	3.07e-240	-	-	-	M	-	-	-	Zinc dependent phospholipase C
HHKAHHOL_01159	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HHKAHHOL_01160	6.81e-225	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHKAHHOL_01161	0.0	-	-	-	M	-	-	-	PFAM sulfatase
HHKAHHOL_01162	2.39e-254	-	-	-	C	ko:K07079	-	ko00000	aldo keto reductase
HHKAHHOL_01163	6.92e-155	-	3.1.3.18	-	C	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_01164	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01165	0.0	-	-	-	C	-	-	-	NADH flavin oxidoreductase NADH oxidase
HHKAHHOL_01166	2.94e-186	aroD	-	-	E	ko:K06889	-	ko00000	Alpha beta
HHKAHHOL_01167	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_01168	3.24e-194	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_01169	7.97e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
HHKAHHOL_01170	2.89e-273	-	-	-	-	-	-	-	-
HHKAHHOL_01171	1.94e-246	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HHKAHHOL_01172	2.43e-267	-	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HHKAHHOL_01173	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01174	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HHKAHHOL_01175	2.66e-220	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HHKAHHOL_01176	6.8e-151	yuaJ	-	-	S	ko:K16789	-	ko00000,ko02000	Proton-coupled thiamine transporter YuaJ
HHKAHHOL_01177	4.08e-182	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_01178	1.5e-257	-	-	-	S	-	-	-	FIST N domain
HHKAHHOL_01179	5.7e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHKAHHOL_01180	3.5e-223	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase II
HHKAHHOL_01181	1.71e-211	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl coa-acyl carrier protein transacylase
HHKAHHOL_01182	1.09e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HHKAHHOL_01183	1.77e-301	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHKAHHOL_01184	4.97e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHKAHHOL_01185	0.0	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHKAHHOL_01186	5.74e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHKAHHOL_01187	3.33e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHKAHHOL_01188	7.53e-49	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.75
HHKAHHOL_01189	0.0	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the Glu Leu Phe Val dehydrogenases family
HHKAHHOL_01190	3.05e-48	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HHKAHHOL_01191	5.77e-58	-	-	-	S	-	-	-	addiction module toxin, RelE StbE family
HHKAHHOL_01192	5.36e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01193	1.8e-99	-	-	-	S	-	-	-	Cbs domain
HHKAHHOL_01194	1.32e-273	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH Band 7 PHB domain protein
HHKAHHOL_01196	1.37e-275	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_01197	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate transporter
HHKAHHOL_01198	4.51e-75	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain protein
HHKAHHOL_01199	1.25e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHKAHHOL_01200	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHKAHHOL_01201	2.51e-283	-	-	-	T	-	-	-	Diguanylate cyclase
HHKAHHOL_01202	3.66e-275	-	-	-	T	-	-	-	Diguanylate cyclase
HHKAHHOL_01203	4.49e-258	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_01204	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 7.50
HHKAHHOL_01205	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHKAHHOL_01206	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHKAHHOL_01207	2.44e-288	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHKAHHOL_01208	8.63e-66	cbiA	-	-	S	ko:K07162	-	ko00000	Cysteine-rich small domain
HHKAHHOL_01209	0.0	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	cobalt chelatase
HHKAHHOL_01210	1.48e-269	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Abc transporter
HHKAHHOL_01211	6.79e-226	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHKAHHOL_01212	0.0	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Fe3 -hydroxamate transport system, periplasmic component
HHKAHHOL_01213	0.0	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	cobalt chelatase
HHKAHHOL_01214	0.0	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HHKAHHOL_01215	0.0	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
HHKAHHOL_01216	3.03e-182	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-3B C17-methyltransferase
HHKAHHOL_01217	2.26e-243	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin biosynthesis protein cbiG
HHKAHHOL_01218	3.8e-177	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C(11)-methyltransferase
HHKAHHOL_01219	5.11e-265	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HHKAHHOL_01220	0.0	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	PFAM Aminotransferase class I and II
HHKAHHOL_01221	2.44e-241	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HHKAHHOL_01222	5.74e-155	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_01223	9.05e-85	-	-	-	H	-	-	-	Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase
HHKAHHOL_01224	3.8e-175	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HHKAHHOL_01225	1.78e-134	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase
HHKAHHOL_01226	1.72e-244	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HHKAHHOL_01227	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HHKAHHOL_01228	1.26e-100	-	-	-	S	-	-	-	SpoIIIAH-like protein
HHKAHHOL_01229	1.46e-138	spoIIIAG	-	-	S	ko:K06396	-	ko00000	Stage III sporulation protein AG
HHKAHHOL_01230	3.47e-123	-	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HHKAHHOL_01231	3.36e-271	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HHKAHHOL_01232	4.32e-78	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HHKAHHOL_01233	1.15e-35	spoIIIAC	-	-	S	ko:K06392	-	ko00000	Stage III sporulation protein AC
HHKAHHOL_01235	3.49e-222	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HHKAHHOL_01236	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HHKAHHOL_01237	7.29e-316	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHKAHHOL_01238	3.95e-308	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01239	1.3e-146	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01241	7.81e-165	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HHKAHHOL_01242	6.05e-93	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHKAHHOL_01243	7.27e-211	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01244	4.02e-121	-	-	-	K	-	-	-	acetyltransferase, gnat
HHKAHHOL_01245	2.95e-193	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HHKAHHOL_01246	1.2e-180	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01247	0.0	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
HHKAHHOL_01248	6.12e-312	-	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_01249	0.0	-	-	-	T	-	-	-	GGDEF domain
HHKAHHOL_01250	5.46e-74	-	-	-	T	-	-	-	Histidine Phosphotransfer domain
HHKAHHOL_01251	1.08e-135	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HHKAHHOL_01252	1.35e-107	greA_2	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHKAHHOL_01253	3.47e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
HHKAHHOL_01255	1.51e-99	-	-	-	-	-	-	-	-
HHKAHHOL_01256	2.64e-304	larC	4.99.1.12	-	P	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HHKAHHOL_01257	5.18e-171	-	-	-	S	ko:K06898	-	ko00000	(AIR) carboxylase
HHKAHHOL_01258	1.36e-125	-	-	-	K	-	-	-	transcriptional regulator TetR family
HHKAHHOL_01259	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HHKAHHOL_01260	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_01261	0.0	lacS	-	-	G	ko:K03292,ko:K11104,ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_01262	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HHKAHHOL_01263	6.93e-259	-	-	-	M	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HHKAHHOL_01264	8.92e-129	-	-	-	I	-	-	-	Acyltransferase family
HHKAHHOL_01265	6.33e-55	-	-	-	K	-	-	-	Transcriptional regulator, AbrB family
HHKAHHOL_01267	2.82e-298	effD	-	-	V	-	-	-	MATE efflux family protein
HHKAHHOL_01268	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHKAHHOL_01269	7.83e-130	degU	-	-	K	-	-	-	response regulator receiver
HHKAHHOL_01270	1.08e-224	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01271	6.15e-230	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHKAHHOL_01272	1.05e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HHKAHHOL_01273	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHKAHHOL_01274	4.6e-63	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HHKAHHOL_01275	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHKAHHOL_01276	4.47e-143	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HHKAHHOL_01277	1.27e-289	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HHKAHHOL_01278	6.85e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHKAHHOL_01280	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHKAHHOL_01281	3.57e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHKAHHOL_01282	1.78e-42	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HHKAHHOL_01283	6.14e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHKAHHOL_01284	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHKAHHOL_01285	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHKAHHOL_01287	7.55e-219	-	-	-	S	-	-	-	NADP oxidoreductase coenzyme F420-dependent
HHKAHHOL_01288	1.98e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HHKAHHOL_01289	4.31e-195	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HHKAHHOL_01290	6.91e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHKAHHOL_01291	6.94e-189	-	-	-	D	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01292	3.87e-202	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Fe-S type, tartrate fumarate subfamily, alpha
HHKAHHOL_01293	1.37e-123	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Fe-S type, tartrate fumarate subfamily, beta
HHKAHHOL_01294	4.86e-150	-	-	-	S	-	-	-	Cupin domain protein
HHKAHHOL_01295	4.87e-193	-	3.6.3.34	-	HP	ko:K02013,ko:K09820	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Abc transporter
HHKAHHOL_01296	4.11e-230	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHKAHHOL_01297	7.09e-273	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHKAHHOL_01298	1.2e-160	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
HHKAHHOL_01299	2.91e-228	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01300	5.51e-239	-	-	-	E	-	-	-	Oxidoreductase NAD-binding domain protein
HHKAHHOL_01301	1.07e-93	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	PFAM thioesterase superfamily
HHKAHHOL_01302	1.97e-159	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	hydrolase, family 3
HHKAHHOL_01303	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	histidine kinase HAMP region domain protein
HHKAHHOL_01304	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HHKAHHOL_01305	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
HHKAHHOL_01306	5.62e-225	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_01307	2.33e-209	-	-	-	P	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_01308	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
HHKAHHOL_01309	0.0	-	-	-	P	-	-	-	esterase
HHKAHHOL_01310	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
HHKAHHOL_01311	5.38e-302	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	family 8
HHKAHHOL_01312	0.0	-	-	-	G	-	-	-	Glycosyltransferase 36 associated
HHKAHHOL_01313	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase 36 superfamily, catalytic domain
HHKAHHOL_01314	2.5e-176	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_01315	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HHKAHHOL_01316	1.03e-216	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems permease components
HHKAHHOL_01317	3.28e-194	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
HHKAHHOL_01318	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HHKAHHOL_01319	2.42e-169	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01320	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01321	2.35e-122	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHKAHHOL_01322	4.91e-242	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHKAHHOL_01323	1.02e-149	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	DnaJ domain protein
HHKAHHOL_01324	4.92e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01325	4.21e-91	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HHKAHHOL_01326	6.73e-245	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	twitching motility protein
HHKAHHOL_01327	0.0	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	uridine kinase
HHKAHHOL_01328	2.21e-167	trmK	2.1.1.217	-	L	ko:K06967	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score
HHKAHHOL_01329	5.97e-267	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHKAHHOL_01330	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHKAHHOL_01331	1.94e-246	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
HHKAHHOL_01333	3.94e-133	-	-	-	F	-	-	-	Cytidylate kinase-like family
HHKAHHOL_01336	0.0	-	-	-	T	-	-	-	Diguanylate cyclase
HHKAHHOL_01337	0.0	-	-	-	L	-	-	-	Putative RNA methylase family UPF0020
HHKAHHOL_01338	1.08e-155	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-l-alanine amidase
HHKAHHOL_01340	5.53e-151	-	-	-	I	-	-	-	PFAM NADPH-dependent FMN reductase
HHKAHHOL_01341	3.15e-295	-	-	-	S	ko:K18475	-	ko00000,ko01000,ko02035	N-methylation of lysine residues in flagellin K00599
HHKAHHOL_01343	1.85e-130	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHKAHHOL_01344	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HHKAHHOL_01345	3.5e-107	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HHKAHHOL_01346	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Abc transporter
HHKAHHOL_01347	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHKAHHOL_01348	1.48e-305	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHKAHHOL_01349	2.83e-285	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHKAHHOL_01350	6.49e-65	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
HHKAHHOL_01352	8.57e-134	-	-	-	-	-	-	-	-
HHKAHHOL_01353	3.98e-256	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHKAHHOL_01354	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HHKAHHOL_01355	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
HHKAHHOL_01356	4.2e-265	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHKAHHOL_01357	2.93e-280	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HHKAHHOL_01358	2.98e-309	-	-	-	S	-	-	-	Conserved protein
HHKAHHOL_01359	9.45e-215	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	mechanosensitive ion channel
HHKAHHOL_01360	4.69e-43	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HHKAHHOL_01361	0.0	hypA2	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16 inactive domain protein
HHKAHHOL_01362	6.78e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHKAHHOL_01364	1.9e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HHKAHHOL_01365	1.97e-146	-	-	-	-	-	-	-	-
HHKAHHOL_01366	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-II aminoacyl-tRNA synthetase family
HHKAHHOL_01368	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HHKAHHOL_01369	1.62e-110	-	-	-	-	-	-	-	-
HHKAHHOL_01370	1.5e-31	-	-	-	-	-	-	-	-
HHKAHHOL_01371	1.2e-167	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
HHKAHHOL_01372	1.4e-190	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01373	3.14e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HHKAHHOL_01374	3.06e-115	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01375	8.85e-208	dapF_2	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHKAHHOL_01377	1.67e-176	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHKAHHOL_01378	0.0	-	-	-	J	ko:K07576	-	ko00000	exonuclease of the beta-lactamase fold involved in RNA processing
HHKAHHOL_01379	8.01e-173	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHKAHHOL_01381	1.24e-271	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHKAHHOL_01382	1.81e-170	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	COG1589 Cell division septal protein
HHKAHHOL_01383	2.12e-254	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHKAHHOL_01384	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHKAHHOL_01385	1.53e-217	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHKAHHOL_01386	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	penicillin-binding protein
HHKAHHOL_01387	0.0	-	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HHKAHHOL_01388	1.31e-109	-	-	-	-	-	-	-	-
HHKAHHOL_01389	2.48e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHKAHHOL_01390	4.27e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HHKAHHOL_01392	5.49e-149	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01393	3.32e-76	-	-	-	S	-	-	-	COG NOG16856 non supervised orthologous group
HHKAHHOL_01394	9.61e-121	secA_2	-	-	U	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01395	3.07e-120	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	solute-binding protein
HHKAHHOL_01396	3.53e-87	-	-	-	G	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_01397	1.51e-260	-	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHKAHHOL_01398	7.29e-42	-	-	-	-	-	-	-	-
HHKAHHOL_01399	2.98e-117	-	-	-	S	-	-	-	COG NOG21479 non supervised orthologous group
HHKAHHOL_01400	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	-transport system
HHKAHHOL_01401	8.68e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HHKAHHOL_01402	4.72e-134	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHKAHHOL_01403	2.27e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHKAHHOL_01404	1.23e-113	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
HHKAHHOL_01405	7.97e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01406	8.99e-99	-	-	-	-	-	-	-	-
HHKAHHOL_01408	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HHKAHHOL_01409	9.4e-128	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01410	6.81e-95	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HHKAHHOL_01411	1.83e-215	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01412	1.73e-145	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT family
HHKAHHOL_01413	6.33e-109	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHKAHHOL_01414	6.06e-30	-	-	-	S	-	-	-	Psort location
HHKAHHOL_01415	1.2e-235	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HHKAHHOL_01416	7.49e-285	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_01417	5.25e-199	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01418	2.2e-294	-	2.7.7.23, 2.7.7.83	-	G	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_01419	2.2e-170	-	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	guanosine tetraphosphate metabolic process
HHKAHHOL_01420	6.07e-184	-	-	-	S	-	-	-	EcsC protein family
HHKAHHOL_01421	3.53e-29	-	-	-	-	-	-	-	-
HHKAHHOL_01422	6.38e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HHKAHHOL_01425	2.63e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HHKAHHOL_01426	2.51e-259	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHKAHHOL_01427	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHKAHHOL_01428	1.6e-52	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHKAHHOL_01429	1.4e-187	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01430	2.74e-138	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHKAHHOL_01431	7.85e-205	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HHKAHHOL_01432	8.31e-226	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase
HHKAHHOL_01433	6.19e-298	-	-	-	S	-	-	-	Lysin motif
HHKAHHOL_01434	7.34e-291	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01435	9.22e-152	-	-	-	S	-	-	-	Colicin V production protein
HHKAHHOL_01436	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHKAHHOL_01438	1.35e-146	-	-	-	-	-	-	-	-
HHKAHHOL_01439	3.92e-240	-	-	-	G	ko:K10540	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_01440	8.36e-231	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system periplasmic component
HHKAHHOL_01441	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01442	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HHKAHHOL_01443	6.56e-64	-	-	-	-	-	-	-	-
HHKAHHOL_01444	1.68e-227	mglC	-	-	G	ko:K10541	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_01445	0.0	mglA	3.6.3.17	-	G	ko:K10542	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	import. Responsible for energy coupling to the transport system
HHKAHHOL_01446	2.58e-239	-	-	-	G	ko:K10540	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_01447	1.27e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01448	1e-214	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01449	1.29e-156	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHKAHHOL_01450	2.26e-312	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HHKAHHOL_01451	1.92e-266	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HHKAHHOL_01452	3.52e-70	-	-	-	-	-	-	-	-
HHKAHHOL_01454	3.01e-131	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HHKAHHOL_01455	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	Belongs to the serpin family
HHKAHHOL_01456	0.0	-	-	-	O	-	-	-	COG COG1404 Subtilisin-like serine proteases
HHKAHHOL_01457	0.0	clpX_1	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHKAHHOL_01459	5.63e-180	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_01460	3.16e-232	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
HHKAHHOL_01461	7.77e-98	-	-	-	FG	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01462	7.59e-39	-	-	-	-	-	-	-	-
HHKAHHOL_01463	4.52e-213	-	-	-	O	-	-	-	Torsin
HHKAHHOL_01464	3.59e-16	-	-	-	-	-	-	-	-
HHKAHHOL_01465	1.9e-215	-	-	-	S	-	-	-	YARHG
HHKAHHOL_01466	1.39e-165	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01467	8.18e-243	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01468	0.0	agcS	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HHKAHHOL_01469	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	ImpB MucB SamB family protein
HHKAHHOL_01470	1.47e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01471	1.69e-180	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
HHKAHHOL_01472	3.73e-202	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01473	1.33e-258	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHKAHHOL_01476	2.81e-106	EbsC	-	-	KT	-	-	-	YbaK proline--tRNA ligase associated domain protein
HHKAHHOL_01477	1.76e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HHKAHHOL_01478	1.93e-257	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HHKAHHOL_01479	3.79e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
HHKAHHOL_01480	1.07e-68	-	-	-	J	-	-	-	ribosomal protein
HHKAHHOL_01481	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHKAHHOL_01482	2.67e-83	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHKAHHOL_01483	1.98e-233	nrnA	3.1.13.3, 3.1.3.7	-	J	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HHKAHHOL_01484	1.59e-216	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHKAHHOL_01485	3.82e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HHKAHHOL_01486	2.08e-249	-	-	-	M	-	-	-	NlpC p60 family protein
HHKAHHOL_01487	2.22e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHKAHHOL_01488	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHKAHHOL_01489	1.89e-224	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HHKAHHOL_01490	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHKAHHOL_01491	3.95e-273	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHKAHHOL_01492	1.04e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHKAHHOL_01493	7.92e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHKAHHOL_01494	4.84e-35	-	-	-	P	-	-	-	Protein of unknown function (DUF4435)
HHKAHHOL_01495	2.08e-14	-	-	-	M	-	-	-	Cell wall-binding repeat protein
HHKAHHOL_01496	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHKAHHOL_01497	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHKAHHOL_01498	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHKAHHOL_01499	6.82e-224	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHKAHHOL_01500	0.0	apeA	-	-	E	-	-	-	M18 family aminopeptidase
HHKAHHOL_01501	1.06e-205	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HHKAHHOL_01502	1.99e-205	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HHKAHHOL_01503	9.81e-200	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HHKAHHOL_01504	5.07e-47	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHKAHHOL_01505	2.76e-216	dagK	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
HHKAHHOL_01506	5.99e-210	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HHKAHHOL_01507	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HHKAHHOL_01508	8.51e-73	glnB1	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HHKAHHOL_01509	1.96e-295	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
HHKAHHOL_01510	4.97e-157	-	-	-	S	-	-	-	Response regulator receiver domain
HHKAHHOL_01511	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHKAHHOL_01512	1.56e-146	yvyE	-	-	S	-	-	-	YigZ family
HHKAHHOL_01514	1.19e-171	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HHKAHHOL_01515	4.82e-195	cvfB	-	-	S	ko:K00243	-	ko00000	S1, RNA binding domain
HHKAHHOL_01516	1.25e-80	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HHKAHHOL_01517	3.37e-06	-	-	-	S	-	-	-	Putative motility protein
HHKAHHOL_01518	4.39e-231	-	-	-	MT	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC p60 family protein
HHKAHHOL_01519	1.45e-149	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Psort location Cytoplasmic, score
HHKAHHOL_01520	4.14e-256	cdaR_3	-	-	QT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HHKAHHOL_01521	6.53e-170	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HHKAHHOL_01522	1.09e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHKAHHOL_01523	1.82e-213	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HHKAHHOL_01524	1.44e-311	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HHKAHHOL_01525	1.46e-115	-	-	-	S	-	-	-	PFAM VanZ family protein
HHKAHHOL_01527	1.53e-244	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHKAHHOL_01528	6.11e-159	-	-	-	-	-	-	-	-
HHKAHHOL_01529	1.44e-268	-	-	-	L	-	-	-	virion core protein (lumpy skin disease virus)
HHKAHHOL_01530	8.74e-260	-	-	-	S	-	-	-	bacterial-type flagellum-dependent swarming motility
HHKAHHOL_01531	3.47e-171	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HHKAHHOL_01532	5.55e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HHKAHHOL_01533	9.53e-284	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HHKAHHOL_01534	1.39e-286	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	phosphoglycerate mutase
HHKAHHOL_01535	5.17e-169	-	-	-	-	-	-	-	-
HHKAHHOL_01536	4.51e-103	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HHKAHHOL_01537	3.3e-278	-	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HHKAHHOL_01538	0.0	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	solute-binding protein
HHKAHHOL_01539	0.0	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_01540	1.69e-198	-	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_01541	2.24e-141	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HHKAHHOL_01542	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHKAHHOL_01543	1.45e-190	-	-	-	K	-	-	-	-acetyltransferase
HHKAHHOL_01544	2.56e-134	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01545	1.73e-269	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHKAHHOL_01546	0.0	-	-	-	K	-	-	-	-acetyltransferase
HHKAHHOL_01547	0.0	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHKAHHOL_01548	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_01549	3.57e-141	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_01550	3.29e-259	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HHKAHHOL_01551	2.85e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HHKAHHOL_01552	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HHKAHHOL_01554	1.94e-215	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_01555	8.41e-316	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHKAHHOL_01556	2.16e-200	-	-	-	M	-	-	-	Cell wall hydrolase
HHKAHHOL_01557	1.62e-276	thlA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HHKAHHOL_01558	7.25e-207	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HHKAHHOL_01559	4.6e-271	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HHKAHHOL_01560	3.69e-185	etfB	-	-	C	ko:K03521	-	ko00000	electron transfer flavoprotein
HHKAHHOL_01561	1.37e-246	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	electron transfer flavoprotein
HHKAHHOL_01562	1.89e-310	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_01563	1.84e-126	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HHKAHHOL_01564	7.34e-221	-	3.4.16.4	-	U	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	ErfK YbiS YcfS YnhG
HHKAHHOL_01565	9.47e-317	thrA	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HHKAHHOL_01566	7.67e-196	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HHKAHHOL_01567	1.19e-232	-	-	-	S	-	-	-	Domain of unknown function (DUF4474)
HHKAHHOL_01568	4.2e-187	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHKAHHOL_01569	1.65e-148	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01570	2.5e-70	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HHKAHHOL_01571	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_01572	9.49e-163	-	-	-	S	ko:K06940	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_01573	1.15e-262	napA	-	-	P	-	-	-	Transporter, CPA2 family
HHKAHHOL_01574	1.15e-193	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HHKAHHOL_01575	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Exonuclease SbcC
HHKAHHOL_01576	4.26e-272	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHKAHHOL_01577	1.87e-97	-	-	-	-	-	-	-	-
HHKAHHOL_01581	1.25e-156	-	-	-	-	-	-	-	-
HHKAHHOL_01582	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase catalytic
HHKAHHOL_01583	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHKAHHOL_01584	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHKAHHOL_01585	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01586	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis
HHKAHHOL_01587	4.82e-183	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHKAHHOL_01588	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	snf2 family
HHKAHHOL_01589	3.75e-129	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HHKAHHOL_01590	1.74e-206	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HHKAHHOL_01591	5.3e-68	-	-	-	-	-	-	-	-
HHKAHHOL_01592	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_01593	2.87e-237	-	-	-	T	-	-	-	GGDEF domain
HHKAHHOL_01594	8.38e-160	-	-	-	K	-	-	-	transcriptional regulator (GntR
HHKAHHOL_01595	5.01e-202	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HHKAHHOL_01596	1.02e-257	-	3.2.1.67	-	G	ko:K01213	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 28 family
HHKAHHOL_01597	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHKAHHOL_01598	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_01599	2.17e-141	-	-	-	-	-	-	-	-
HHKAHHOL_01600	6.16e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HHKAHHOL_01601	1.23e-273	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG COG0842 ABC-type multidrug transport system, permease component
HHKAHHOL_01602	1.55e-224	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_01603	6.47e-266	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_01604	8.42e-142	-	-	-	T	-	-	-	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHKAHHOL_01605	1.2e-189	ycfH	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HHKAHHOL_01606	1.77e-193	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01607	0.0	-	-	-	S	-	-	-	DNA modification repair radical SAM protein
HHKAHHOL_01608	2.08e-209	-	-	-	K	-	-	-	lysR substrate binding domain
HHKAHHOL_01609	2.06e-151	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01610	1.11e-202	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
HHKAHHOL_01611	8.73e-314	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_01612	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HHKAHHOL_01613	5.16e-248	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHKAHHOL_01614	1.34e-115	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, small subunit
HHKAHHOL_01616	0.0	pip1	-	-	S	ko:K01421	-	ko00000	YhgE Pip
HHKAHHOL_01617	2.3e-97	-	-	-	S	-	-	-	domain protein
HHKAHHOL_01618	0.0	pip1	-	-	S	ko:K01421	-	ko00000	YhgE Pip
HHKAHHOL_01619	2.8e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHKAHHOL_01620	3.54e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HHKAHHOL_01621	3.89e-106	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHKAHHOL_01622	5.1e-97	-	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Two component signalling adaptor domain
HHKAHHOL_01623	3.2e-224	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01624	5.96e-206	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain
HHKAHHOL_01625	7.76e-192	yidA	-	-	S	-	-	-	HAD-superfamily hydrolase, subfamily IIB
HHKAHHOL_01626	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHKAHHOL_01627	0.0	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx GppA phosphatase
HHKAHHOL_01628	3.53e-312	-	-	-	E	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HHKAHHOL_01629	1.96e-274	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HHKAHHOL_01630	4.74e-232	-	-	-	U	-	-	-	Domain of unknown function (DUF5050)
HHKAHHOL_01631	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyltransferase 36 associated
HHKAHHOL_01632	7.28e-243	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	lacI family
HHKAHHOL_01633	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HHKAHHOL_01634	2.82e-206	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems permease components
HHKAHHOL_01635	4.16e-199	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
HHKAHHOL_01636	0.0	-	-	-	T	-	-	-	GGDEF domain
HHKAHHOL_01638	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHKAHHOL_01639	1.06e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHKAHHOL_01640	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHKAHHOL_01641	0.0	-	-	-	L	ko:K09749	-	ko00000	PALM domain HD hydrolase domain and
HHKAHHOL_01642	4.85e-24	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01643	2.16e-300	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHKAHHOL_01644	7.5e-76	spoIIAA	-	-	T	ko:K04749,ko:K06378	-	ko00000,ko03021	antisigma factor binding
HHKAHHOL_01645	5.39e-96	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HHKAHHOL_01646	1.72e-163	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHKAHHOL_01647	8.24e-310	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_01648	1.06e-191	-	-	-	M	-	-	-	Membrane
HHKAHHOL_01649	9.49e-265	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01650	7.31e-170	-	-	-	G	ko:K03491	-	ko00000,ko03000	PRD domain protein
HHKAHHOL_01651	2.94e-262	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HHKAHHOL_01652	0.0	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HHKAHHOL_01653	1.28e-109	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, glucose subfamily, IIA
HHKAHHOL_01654	1.18e-183	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HHKAHHOL_01655	9.07e-179	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHKAHHOL_01656	7.34e-72	-	-	-	S	-	-	-	PilZ domain
HHKAHHOL_01657	3.37e-250	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHKAHHOL_01658	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
HHKAHHOL_01659	2.02e-245	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHKAHHOL_01660	1.13e-191	yihY	-	-	H	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HHKAHHOL_01661	0.0	-	-	-	D	ko:K06381	-	ko00000	SpoIID LytB domain protein
HHKAHHOL_01662	3.69e-159	-	-	-	S	-	-	-	TIGR00266 family
HHKAHHOL_01663	6.4e-97	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHKAHHOL_01664	0.0	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HHKAHHOL_01665	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_01666	9.43e-162	-	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HHKAHHOL_01667	7.09e-65	-	-	-	-	-	-	-	-
HHKAHHOL_01668	4.71e-81	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HHKAHHOL_01669	3.41e-172	-	-	-	N	-	-	-	Chemotaxis phosphatase CheX
HHKAHHOL_01670	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HHKAHHOL_01671	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_01672	2.24e-197	-	-	-	-	-	-	-	-
HHKAHHOL_01673	3.12e-115	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHKAHHOL_01674	9.6e-195	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHKAHHOL_01675	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHKAHHOL_01676	5.05e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHKAHHOL_01677	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHKAHHOL_01678	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage ii sporulation protein e
HHKAHHOL_01679	6.5e-246	-	-	-	C	ko:K19265	-	ko00000,ko01000	aldo keto reductase
HHKAHHOL_01680	1.83e-46	-	-	-	D	-	-	-	septum formation initiator
HHKAHHOL_01681	4.92e-104	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01682	1.37e-60	yabP	-	-	S	-	-	-	Sporulation protein YabP
HHKAHHOL_01683	3.76e-48	hslR	-	-	J	-	-	-	S4 domain protein
HHKAHHOL_01684	5.59e-41	hslR	-	-	J	-	-	-	S4 domain protein
HHKAHHOL_01685	7.05e-152	-	-	-	-	-	-	-	-
HHKAHHOL_01686	5.75e-184	-	-	-	-	-	-	-	-
HHKAHHOL_01687	1.22e-176	-	-	-	L	-	-	-	viral genome integration into host DNA
HHKAHHOL_01688	8.24e-19	-	-	-	-	-	-	-	-
HHKAHHOL_01690	2.56e-51	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHKAHHOL_01691	0.0	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	phosphoglucomutase phosphomannomutase alpha beta alpha domain II
HHKAHHOL_01692	1.72e-265	-	-	-	S	-	-	-	PEGA domain
HHKAHHOL_01693	2.24e-237	cotS	-	-	S	ko:K06331,ko:K06337	-	ko00000	spore coat protein, CotS
HHKAHHOL_01694	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HHKAHHOL_01695	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHKAHHOL_01696	3.85e-152	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
HHKAHHOL_01697	2.53e-123	-	-	-	C	-	-	-	Flavodoxin domain
HHKAHHOL_01698	1.74e-57	-	-	-	-	-	-	-	-
HHKAHHOL_01699	2.83e-249	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HHKAHHOL_01700	1.39e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHKAHHOL_01701	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HHKAHHOL_01702	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE
HHKAHHOL_01703	2.05e-198	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHKAHHOL_01704	3.14e-156	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Protease subunit of ATP-dependent
HHKAHHOL_01705	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HHKAHHOL_01706	2.8e-171	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HHKAHHOL_01707	0.0	-	-	-	S	ko:K03699	-	ko00000,ko02042	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01708	2.84e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HHKAHHOL_01709	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHKAHHOL_01710	4.84e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHKAHHOL_01711	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Abc transporter
HHKAHHOL_01712	5.66e-298	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HHKAHHOL_01713	3.41e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01714	0.0	-	-	-	E	-	-	-	Belongs to the alpha-IPM synthase homocitrate synthase family
HHKAHHOL_01715	7.79e-237	-	-	-	T	-	-	-	phosphorelay signal transduction system
HHKAHHOL_01718	1.38e-71	-	-	-	-	-	-	-	-
HHKAHHOL_01719	2.14e-58	-	-	-	-	-	-	-	-
HHKAHHOL_01720	0.0	-	-	-	M	-	-	-	cell wall binding repeat
HHKAHHOL_01721	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	elongation factor g
HHKAHHOL_01722	0.0	-	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
HHKAHHOL_01723	2.96e-210	-	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HHKAHHOL_01724	6.4e-204	-	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
HHKAHHOL_01725	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase
HHKAHHOL_01726	8.69e-149	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HHKAHHOL_01727	0.0	-	-	-	G	ko:K09955	-	ko00000	protein conserved in bacteria
HHKAHHOL_01728	5.89e-42	sasP	-	-	S	ko:K06421	-	ko00000	'small, acid-soluble spore protein
HHKAHHOL_01729	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHKAHHOL_01730	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHKAHHOL_01731	2.83e-121	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01732	6.47e-149	-	-	-	S	ko:K07025	-	ko00000	IA, variant 3
HHKAHHOL_01733	2.13e-130	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, gnat family
HHKAHHOL_01735	3.3e-189	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHKAHHOL_01736	1.77e-40	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHKAHHOL_01737	5.9e-46	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	sequence-specific DNA binding
HHKAHHOL_01738	3.5e-291	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHKAHHOL_01739	2.43e-138	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHKAHHOL_01740	4.13e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHKAHHOL_01741	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHKAHHOL_01742	1.93e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HHKAHHOL_01743	7.3e-217	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	carbamate kinase
HHKAHHOL_01744	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HHKAHHOL_01745	1.1e-93	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HHKAHHOL_01746	3.56e-146	-	-	-	S	-	-	-	metallophosphoesterase
HHKAHHOL_01748	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01749	1.66e-263	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHKAHHOL_01750	2.36e-238	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HHKAHHOL_01751	2.21e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HHKAHHOL_01753	3.22e-166	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_01755	1.81e-166	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01756	3.85e-301	adh	-	-	C	-	-	-	alcohol dehydrogenase
HHKAHHOL_01757	2.5e-233	spoVAD	-	-	I	ko:K06406	-	ko00000	stage v sporulation protein ad
HHKAHHOL_01758	7.73e-79	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HHKAHHOL_01759	2.96e-72	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_01760	2.6e-166	-	-	-	K	-	-	-	transcriptional regulator (GntR
HHKAHHOL_01762	4.04e-266	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HHKAHHOL_01763	1.51e-199	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHKAHHOL_01764	1.16e-209	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HHKAHHOL_01765	0.0	XK27_03135	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HHKAHHOL_01766	4.81e-50	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HHKAHHOL_01767	4.15e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HHKAHHOL_01768	7.66e-130	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HHKAHHOL_01770	1.91e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HHKAHHOL_01771	7.35e-219	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHKAHHOL_01772	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHKAHHOL_01773	6.32e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Phosphatase
HHKAHHOL_01774	8.37e-258	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHKAHHOL_01775	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHKAHHOL_01776	6.8e-161	yugP	-	-	S	ko:K06973	-	ko00000	zinc metallopeptidase
HHKAHHOL_01777	9.74e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHKAHHOL_01778	8.12e-100	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHKAHHOL_01779	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHKAHHOL_01780	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHKAHHOL_01781	2.56e-95	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HHKAHHOL_01782	9.53e-93	-	-	-	S	-	-	-	Bacterial PH domain
HHKAHHOL_01783	1.04e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HHKAHHOL_01784	3.79e-101	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HHKAHHOL_01785	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHKAHHOL_01786	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHKAHHOL_01787	4.5e-211	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase, GNAT family
HHKAHHOL_01788	1.53e-139	-	-	-	F	-	-	-	Nudix hydrolase
HHKAHHOL_01789	0.0	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HHKAHHOL_01790	4.77e-116	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHKAHHOL_01791	2.65e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HHKAHHOL_01792	1.89e-51	-	-	-	S	-	-	-	Excisionase from transposon Tn916
HHKAHHOL_01793	7.44e-296	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01795	2.17e-82	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HHKAHHOL_01796	3.15e-277	-	2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHKAHHOL_01797	1.71e-120	-	-	-	S	-	-	-	membrane
HHKAHHOL_01798	0.0	-	-	-	T	-	-	-	response regulator
HHKAHHOL_01799	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01800	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
HHKAHHOL_01801	2.12e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
HHKAHHOL_01802	2.28e-200	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems permease components
HHKAHHOL_01803	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_01804	0.0	-	-	-	G	-	-	-	transport
HHKAHHOL_01805	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase 36 superfamily, catalytic domain
HHKAHHOL_01806	2.47e-290	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
HHKAHHOL_01807	1.97e-169	-	-	-	S	-	-	-	Radical SAM-linked protein
HHKAHHOL_01808	0.0	-	-	-	C	-	-	-	radical SAM domain protein
HHKAHHOL_01810	4.02e-262	-	-	-	S	-	-	-	Acyltransferase family
HHKAHHOL_01811	6.78e-308	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHKAHHOL_01812	9.24e-140	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HHKAHHOL_01813	2.9e-293	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHKAHHOL_01814	1.45e-153	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHKAHHOL_01815	9.94e-267	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHKAHHOL_01816	2.23e-129	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHKAHHOL_01817	2.43e-83	-	-	-	K	-	-	-	iron dependent repressor
HHKAHHOL_01818	2.23e-234	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHKAHHOL_01819	0.0	-	-	-	C	-	-	-	UPF0313 protein
HHKAHHOL_01820	6.1e-172	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHKAHHOL_01821	9.58e-210	-	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	COG0739 Membrane proteins related to metalloendopeptidases
HHKAHHOL_01822	0.0	pepD	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Dipeptidase
HHKAHHOL_01823	3.4e-202	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HHKAHHOL_01824	1.45e-92	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01825	1.22e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHKAHHOL_01826	2.9e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HHKAHHOL_01827	9.79e-119	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HHKAHHOL_01828	4.26e-115	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHKAHHOL_01829	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HHKAHHOL_01830	2.61e-49	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHKAHHOL_01831	3.41e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HHKAHHOL_01832	6.85e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HHKAHHOL_01833	1.68e-197	yicC	-	-	S	-	-	-	TIGR00255 family
HHKAHHOL_01834	2.04e-123	niaR	-	-	K	ko:K07105	-	ko00000	3H domain
HHKAHHOL_01835	3.57e-200	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HHKAHHOL_01836	3.56e-301	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHKAHHOL_01837	6.82e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01838	8.76e-14	-	-	-	G	-	-	-	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHKAHHOL_01839	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	Oligoendopeptidase f
HHKAHHOL_01840	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HHKAHHOL_01841	2.33e-286	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HHKAHHOL_01842	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HHKAHHOL_01843	1.28e-174	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_01844	1.39e-40	sasP	-	-	S	ko:K06421	-	ko00000	'small, acid-soluble spore protein
HHKAHHOL_01845	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHKAHHOL_01846	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HHKAHHOL_01847	8.01e-77	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01848	2.69e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HHKAHHOL_01849	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHKAHHOL_01850	1.79e-244	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HHKAHHOL_01851	2.26e-244	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HHKAHHOL_01852	1.13e-269	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HHKAHHOL_01853	1.33e-166	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HHKAHHOL_01854	1.02e-172	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHKAHHOL_01855	8.6e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHKAHHOL_01856	4.29e-161	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HHKAHHOL_01857	1.84e-144	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HHKAHHOL_01858	2.25e-215	-	-	-	G	-	-	-	Polysaccharide deacetylase
HHKAHHOL_01859	1.06e-36	-	-	-	-	-	-	-	-
HHKAHHOL_01860	2.89e-272	-	-	-	G	-	-	-	Major Facilitator
HHKAHHOL_01861	1.44e-86	-	-	-	S	-	-	-	TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 family
HHKAHHOL_01862	2.48e-57	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HHKAHHOL_01863	1.11e-84	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01864	3.29e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHKAHHOL_01865	1.29e-105	-	-	-	K	-	-	-	Transcriptional regulator
HHKAHHOL_01866	6.29e-194	-	-	-	T	-	-	-	EDD domain protein, DegV family
HHKAHHOL_01867	3.33e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHKAHHOL_01868	2.55e-197	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_01869	1.08e-181	-	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_01870	1.78e-308	-	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	import. Responsible for energy coupling to the transport system
HHKAHHOL_01871	1.26e-192	-	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HHKAHHOL_01872	4.3e-223	-	-	-	K	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HHKAHHOL_01873	1.53e-245	rsmH2	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHKAHHOL_01874	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1266)
HHKAHHOL_01875	3.88e-198	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01876	0.0	pgi	2.2.1.2, 5.3.1.9	-	G	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HHKAHHOL_01877	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHKAHHOL_01878	3.94e-34	-	-	-	-	-	-	-	-
HHKAHHOL_01879	3.03e-96	-	-	-	S	-	-	-	zinc-ribbon family
HHKAHHOL_01880	6.36e-204	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HHKAHHOL_01881	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	3'-5' exonuclease
HHKAHHOL_01882	1.23e-173	-	-	-	-	-	-	-	-
HHKAHHOL_01883	2.84e-85	-	-	-	-	-	-	-	-
HHKAHHOL_01884	0.0	-	-	-	L	-	-	-	helicase
HHKAHHOL_01885	3.55e-52	-	-	-	-	-	-	-	-
HHKAHHOL_01886	1.69e-133	-	-	-	-	-	-	-	-
HHKAHHOL_01889	2.72e-57	-	-	-	E	-	-	-	Pfam:DUF955
HHKAHHOL_01890	8.57e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01891	1.66e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HHKAHHOL_01892	7.57e-132	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HHKAHHOL_01893	6.93e-147	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HHKAHHOL_01894	6.7e-179	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HHKAHHOL_01895	7.17e-306	-	-	-	L	-	-	-	helicase
HHKAHHOL_01896	5.88e-102	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate ion binding
HHKAHHOL_01897	4.42e-136	-	-	-	V	-	-	-	type I restriction-modification system
HHKAHHOL_01898	1.48e-49	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01899	2.51e-299	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HHKAHHOL_01900	3.98e-70	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HHKAHHOL_01901	9.05e-152	-	-	-	S	ko:K09807	-	ko00000	Protein of unknown function (DUF541)
HHKAHHOL_01902	5.56e-154	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
HHKAHHOL_01903	5.67e-96	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01904	9.04e-295	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HHKAHHOL_01905	2.84e-284	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01906	1.63e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHKAHHOL_01907	1.78e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HHKAHHOL_01908	1.17e-117	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01909	2.69e-312	-	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
HHKAHHOL_01910	3.85e-197	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHKAHHOL_01911	1.03e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHKAHHOL_01912	0.0	-	-	-	M	ko:K19294	-	ko00000	Membrane protein involved in D-alanine export
HHKAHHOL_01913	6.32e-224	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHKAHHOL_01914	7.88e-141	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
HHKAHHOL_01915	1.5e-162	-	-	-	C	-	-	-	binding domain protein
HHKAHHOL_01916	5.89e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHKAHHOL_01917	1.55e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HHKAHHOL_01918	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHKAHHOL_01919	5.05e-104	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHKAHHOL_01921	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HHKAHHOL_01922	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HHKAHHOL_01923	6.45e-109	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HHKAHHOL_01924	8.61e-25	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01925	7.34e-242	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase C-terminal domain
HHKAHHOL_01926	0.0	-	-	-	G	-	-	-	Beta-galactosidase
HHKAHHOL_01927	1.26e-103	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01928	1.57e-180	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_01929	8.53e-164	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_01930	5.78e-289	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
HHKAHHOL_01931	4.23e-192	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM response regulator receiver
HHKAHHOL_01932	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Galactose mutarotase-like
HHKAHHOL_01933	3.59e-303	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	hydrolase, family 3
HHKAHHOL_01934	1.38e-108	-	-	-	S	-	-	-	Acetyltransferase, gnat family
HHKAHHOL_01935	5.32e-48	-	-	-	-	-	-	-	-
HHKAHHOL_01936	0.0	-	-	-	K	-	-	-	system, fructose subfamily, IIA component
HHKAHHOL_01937	3.87e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHKAHHOL_01938	7.41e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHKAHHOL_01939	0.0	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHKAHHOL_01940	1.66e-51	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHKAHHOL_01941	9.63e-230	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	PFAM Peptidase M19, renal dipeptidase
HHKAHHOL_01942	0.0	malP_1	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHKAHHOL_01943	5.76e-211	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_01944	4.39e-198	-	-	-	S	-	-	-	Putative adhesin
HHKAHHOL_01945	2.44e-140	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01946	3.74e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
HHKAHHOL_01947	2.1e-216	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHKAHHOL_01948	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HHKAHHOL_01949	9.72e-222	-	-	-	S	-	-	-	Secreted protein
HHKAHHOL_01950	6.91e-233	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HHKAHHOL_01951	2.25e-199	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis protein (MCP) signalling domain
HHKAHHOL_01952	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HHKAHHOL_01953	3.03e-182	truA1	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHKAHHOL_01954	1.06e-134	sleC	-	-	M	-	-	-	Peptidoglycan binding domain protein
HHKAHHOL_01955	3.09e-207	-	-	-	L	-	-	-	Resolvase, N terminal domain
HHKAHHOL_01957	1.08e-21	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HHKAHHOL_01959	1.05e-150	sleC	-	-	M	-	-	-	Peptidoglycan binding domain protein
HHKAHHOL_01960	0.0	eutA	-	-	E	ko:K04019	ko00564,ko01100,map00564,map01100	ko00000,ko00001	PFAM Ethanolamine utilisation
HHKAHHOL_01961	0.0	eutB	4.3.1.7	-	E	ko:K03735	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	PFAM Ethanolamine ammonia lyase large subunit
HHKAHHOL_01962	1.02e-187	eutC	4.3.1.7	-	E	ko:K03736	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the EutC family
HHKAHHOL_01963	1.75e-12	-	-	-	E	ko:K03294	-	ko00000	amino acid
HHKAHHOL_01964	1.76e-162	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_01965	7.98e-310	-	-	-	E	ko:K03294	-	ko00000	amino acid
HHKAHHOL_01966	0.0	-	-	-	EG	-	-	-	metal-dependent hydrolase with the TIM-barrel fold
HHKAHHOL_01967	1.58e-198	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHKAHHOL_01968	2.03e-250	-	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta
HHKAHHOL_01969	2.07e-299	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major Facilitator
HHKAHHOL_01970	1.1e-138	-	-	-	S	-	-	-	RelA SpoT domain protein
HHKAHHOL_01971	1.36e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate binding protein
HHKAHHOL_01972	3.49e-191	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HHKAHHOL_01973	9.98e-190	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
HHKAHHOL_01974	8.7e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHKAHHOL_01975	5.63e-145	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HHKAHHOL_01976	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
HHKAHHOL_01977	3.15e-154	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
HHKAHHOL_01978	9.28e-307	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_01979	2.04e-293	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHKAHHOL_01980	2.25e-105	-	-	-	M	-	-	-	Coat F domain
HHKAHHOL_01981	1.23e-210	-	-	-	C	ko:K07138	-	ko00000	binding domain protein
HHKAHHOL_01982	3.15e-228	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01983	0.0	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_01984	1.29e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HHKAHHOL_01985	4.14e-256	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HHKAHHOL_01986	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC-type transport system involved in lipoprotein release permease component
HHKAHHOL_01987	2.38e-173	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_01988	1.16e-17	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HHKAHHOL_01989	2.95e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	Mate efflux family protein
HHKAHHOL_01990	3.32e-206	-	-	-	K	-	-	-	COG2207 AraC-type DNA-binding domain-containing proteins
HHKAHHOL_01991	8.8e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_01993	4.2e-19	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_01994	5.97e-138	-	-	-	K	-	-	-	transcriptional regulator LuxR family
HHKAHHOL_01995	1.85e-300	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_01996	4.97e-138	-	-	-	-	-	-	-	-
HHKAHHOL_01997	2.66e-156	-	-	-	-	-	-	-	-
HHKAHHOL_01998	7e-158	-	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HHKAHHOL_01999	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02000	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_02002	5.72e-94	-	-	-	S	-	-	-	FMN-binding domain protein
HHKAHHOL_02003	1.59e-49	-	-	-	-	-	-	-	-
HHKAHHOL_02004	6.01e-211	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHKAHHOL_02005	2.03e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHKAHHOL_02006	6.67e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HHKAHHOL_02007	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
HHKAHHOL_02008	3.34e-107	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase, small
HHKAHHOL_02009	3.34e-241	-	-	-	-	-	-	-	-
HHKAHHOL_02010	8.47e-182	-	-	-	S	-	-	-	Methyltransferase domain protein
HHKAHHOL_02011	9.48e-204	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHKAHHOL_02012	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses
HHKAHHOL_02013	6.6e-301	-	-	-	C	ko:K07079	-	ko00000	aldo keto reductase
HHKAHHOL_02014	3.83e-194	-	-	-	S	ko:K06864	-	ko00000	TIGR00268 family
HHKAHHOL_02015	1.94e-66	-	-	-	S	ko:K19092	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
HHKAHHOL_02016	5.91e-46	-	-	-	NT	-	-	-	Phage tail tape measure protein TP901
HHKAHHOL_02017	2.79e-75	-	-	-	S	-	-	-	addiction module toxin, RelE StbE family
HHKAHHOL_02018	2.58e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HHKAHHOL_02019	4.93e-26	-	-	-	-	-	-	-	-
HHKAHHOL_02020	6.27e-234	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_02021	2.41e-131	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_02022	1.06e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HHKAHHOL_02023	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02024	0.0	-	-	-	M	-	-	-	PFAM sulfatase
HHKAHHOL_02026	1.85e-201	-	-	-	P	ko:K07216	-	ko00000	Hemerythrin HHE cation binding domain
HHKAHHOL_02028	9.8e-41	-	-	-	K	-	-	-	Helix-turn-helix domain
HHKAHHOL_02029	2.28e-63	-	-	-	-	-	-	-	-
HHKAHHOL_02030	3.78e-132	-	-	-	S	ko:K06952	-	ko00000	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02031	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_02032	7.48e-189	-	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	COG0775 Nucleoside phosphorylase
HHKAHHOL_02033	4.29e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHKAHHOL_02034	1.51e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHKAHHOL_02035	8.47e-201	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HHKAHHOL_02036	5.29e-131	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HHKAHHOL_02037	9.11e-180	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HHKAHHOL_02038	1.44e-108	-	-	-	T	-	-	-	Nacht domain
HHKAHHOL_02039	3.11e-36	-	-	-	S	-	-	-	Putative tranposon-transfer assisting protein
HHKAHHOL_02040	5.91e-209	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02041	2.18e-216	-	-	-	L	-	-	-	YodL-like
HHKAHHOL_02042	2.15e-52	-	-	-	-	-	-	-	-
HHKAHHOL_02043	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHKAHHOL_02044	7.41e-131	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HHKAHHOL_02045	2.13e-295	-	-	-	EGP	-	-	-	Major Facilitator
HHKAHHOL_02047	1.71e-85	-	-	-	S	-	-	-	LURP-one-related
HHKAHHOL_02048	7.81e-113	thiW	-	-	S	-	-	-	ThiW protein
HHKAHHOL_02049	1.6e-269	cytX	-	-	F	-	-	-	PFAM Permease for cytosine purines, uracil, thiamine, allantoin
HHKAHHOL_02050	6.84e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHKAHHOL_02051	4.53e-59	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02052	1.67e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
HHKAHHOL_02053	7.73e-79	-	-	-	-	-	-	-	-
HHKAHHOL_02054	9.37e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02055	3.03e-27	-	-	-	-	-	-	-	-
HHKAHHOL_02056	4.41e-32	-	-	-	-	-	-	-	-
HHKAHHOL_02057	1.93e-306	-	-	-	S	ko:K06926	-	ko00000	Psort location Cytoplasmic, score
HHKAHHOL_02058	6.64e-161	-	-	-	S	-	-	-	RloB-like protein
HHKAHHOL_02059	1.09e-296	-	-	-	-	-	-	-	-
HHKAHHOL_02060	2.29e-06	mshQ	-	-	U	ko:K12287	-	ko00000,ko02044	domain, Protein
HHKAHHOL_02061	1.05e-121	lepB1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHKAHHOL_02063	5.88e-312	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
HHKAHHOL_02064	0.0	-	-	-	EK	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02065	1.76e-131	-	-	-	-	-	-	-	-
HHKAHHOL_02066	2.31e-133	-	-	-	-	-	-	-	-
HHKAHHOL_02067	8.46e-206	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHKAHHOL_02068	2.04e-151	GntR	-	-	K	-	-	-	domain protein
HHKAHHOL_02069	0.0	gerA	-	-	EG	ko:K06310	-	ko00000	GerA spore germination protein
HHKAHHOL_02070	0.0	-	-	-	E	-	-	-	Spore germination protein
HHKAHHOL_02071	1.37e-136	spoIIR	-	-	S	ko:K06387	-	ko00000	stage ii sporulation protein r
HHKAHHOL_02072	1.08e-101	ywiB	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02073	3.08e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02074	2.96e-302	-	-	-	O	-	-	-	Bacterial trigger factor protein (TF) C-terminus
HHKAHHOL_02075	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HHKAHHOL_02076	2.04e-223	lacX	-	-	G	-	-	-	Aldose 1-epimerase
HHKAHHOL_02077	1.43e-82	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HHKAHHOL_02078	1.83e-20	scfA	-	-	S	-	-	-	six-cysteine peptide
HHKAHHOL_02079	0.0	scfB	-	-	C	ko:K06871	-	ko00000	Radical SAM
HHKAHHOL_02080	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHKAHHOL_02081	7.47e-63	ysdA	-	-	L	-	-	-	Membrane
HHKAHHOL_02082	4.68e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHKAHHOL_02083	7.25e-289	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HHKAHHOL_02084	2.47e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_02085	0.0	-	-	-	M	-	-	-	domain, Protein
HHKAHHOL_02086	6.37e-265	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC-type antimicrobial peptide transport system, permease component
HHKAHHOL_02087	8.56e-302	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHKAHHOL_02088	9.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHKAHHOL_02089	1.2e-126	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHKAHHOL_02090	1.34e-232	-	-	-	-	-	-	-	-
HHKAHHOL_02091	1.53e-114	-	-	-	-	-	-	-	-
HHKAHHOL_02092	5.3e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	DNA-binding helix-turn-helix protein
HHKAHHOL_02093	3.85e-201	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHKAHHOL_02094	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHKAHHOL_02095	5.1e-153	-	-	-	P	-	-	-	domain protein
HHKAHHOL_02096	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen
HHKAHHOL_02097	3.04e-132	-	-	-	-	-	-	-	-
HHKAHHOL_02098	2.13e-201	-	-	-	CO	-	-	-	Redoxin family
HHKAHHOL_02099	1.58e-209	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HHKAHHOL_02100	6.39e-25	-	-	-	-	-	-	-	-
HHKAHHOL_02101	1.68e-155	cutR	-	-	T	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02102	1.3e-264	arlS	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HHKAHHOL_02103	4.15e-297	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HHKAHHOL_02104	0.0	-	-	-	O	ko:K04045	-	ko00000,ko03110	Belongs to the heat shock protein 70 family
HHKAHHOL_02105	3.63e-137	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
HHKAHHOL_02106	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp
HHKAHHOL_02107	1.37e-116	-	-	-	-	-	-	-	-
HHKAHHOL_02108	1.08e-76	-	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HHKAHHOL_02109	1.24e-204	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_02110	1.55e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HHKAHHOL_02111	7.38e-157	-	-	-	NOT	ko:K16511	-	ko00000	Negative regulator of genetic competence (MecA)
HHKAHHOL_02113	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHKAHHOL_02114	0.0	pap	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02115	1.16e-100	-	2.4.1.280	GH94	G	ko:K18675	ko00520,map00520	ko00000,ko00001,ko01000	Glycosyltransferase 36 associated
HHKAHHOL_02116	7.24e-101	-	-	-	T	-	-	-	response regulator
HHKAHHOL_02117	1.86e-108	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02118	5.52e-101	-	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHKAHHOL_02119	4.48e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHKAHHOL_02120	1.5e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHKAHHOL_02121	1.66e-126	-	-	-	S	-	-	-	membrane
HHKAHHOL_02122	5.03e-262	-	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
HHKAHHOL_02123	0.0	-	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	phosphoglucomutase phosphomannomutase alpha beta alpha domain II
HHKAHHOL_02124	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HHKAHHOL_02125	1.3e-242	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_02126	5.01e-136	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHKAHHOL_02127	0.0	-	-	-	G	-	-	-	Extracellular solute-binding protein
HHKAHHOL_02128	3.31e-239	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02129	2.79e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02130	0.0	-	5.1.3.11	-	G	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HHKAHHOL_02131	4.42e-293	-	2.4.1.281	-	G	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HHKAHHOL_02132	8.74e-265	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	PFAM Glycosidase
HHKAHHOL_02133	1.47e-263	-	-	-	E	-	-	-	cellulose binding
HHKAHHOL_02134	5.81e-271	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHKAHHOL_02135	0.0	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHKAHHOL_02136	1.38e-279	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HHKAHHOL_02137	2.53e-253	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_02138	1.97e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
HHKAHHOL_02139	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HHKAHHOL_02140	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHKAHHOL_02141	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHKAHHOL_02142	3.36e-215	purC	6.3.2.6, 6.3.4.13	-	F	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	ko00000,ko00001,ko00002,ko01000,ko03000	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HHKAHHOL_02144	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHKAHHOL_02145	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HHKAHHOL_02146	5.44e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHKAHHOL_02147	4.96e-289	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HHKAHHOL_02148	2.16e-239	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHKAHHOL_02150	1.71e-203	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ family
HHKAHHOL_02151	2.54e-218	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HHKAHHOL_02152	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHKAHHOL_02153	6.95e-145	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHKAHHOL_02154	2.05e-151	hprA	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase
HHKAHHOL_02155	5.22e-245	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HHKAHHOL_02156	1.08e-213	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02158	4.17e-107	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HHKAHHOL_02160	2.42e-299	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02161	6.81e-173	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHKAHHOL_02162	5.66e-258	-	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HHKAHHOL_02163	1.77e-192	-	-	-	F	-	-	-	PFAM purine or other phosphorylase family 1
HHKAHHOL_02164	6.05e-221	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02165	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HHKAHHOL_02166	2.41e-298	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0160)
HHKAHHOL_02167	7.97e-252	-	-	-	D	-	-	-	domain, Protein
HHKAHHOL_02168	0.0	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02169	7.65e-61	-	-	-	-	-	-	-	-
HHKAHHOL_02170	2.08e-287	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02171	3.31e-80	-	-	-	L	-	-	-	PFAM Bacterial transcription activator, effector binding
HHKAHHOL_02172	5.15e-95	-	-	-	K	-	-	-	Sigma-70, region 4
HHKAHHOL_02173	2.97e-54	-	-	-	S	-	-	-	Helix-turn-helix domain
HHKAHHOL_02174	9.67e-35	-	-	-	S	-	-	-	Excisionase from transposon Tn916
HHKAHHOL_02175	1.83e-226	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HHKAHHOL_02176	1.19e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHKAHHOL_02177	9.87e-62	ylmC	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
HHKAHHOL_02178	4.04e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHKAHHOL_02179	7.76e-81	-	-	-	-	-	-	-	-
HHKAHHOL_02180	1.84e-122	yqeG	-	-	F	ko:K07015	-	ko00000	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668
HHKAHHOL_02181	1.66e-101	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HHKAHHOL_02182	1.74e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHKAHHOL_02183	2.36e-91	-	-	-	S	-	-	-	NYN domain
HHKAHHOL_02185	5.37e-309	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
HHKAHHOL_02186	4.13e-276	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HHKAHHOL_02187	1.22e-47	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02188	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	helicase
HHKAHHOL_02189	9.49e-207	-	-	-	K	-	-	-	lysR substrate binding domain
HHKAHHOL_02192	6.09e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HHKAHHOL_02193	2.54e-244	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHKAHHOL_02194	1.39e-120	-	-	-	-	-	-	-	-
HHKAHHOL_02195	1.68e-224	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHKAHHOL_02196	3.15e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02197	4.97e-97	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHKAHHOL_02198	8.63e-165	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HHKAHHOL_02199	1.93e-105	ydiB	-	-	K	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HHKAHHOL_02200	7.01e-109	-	-	-	S	-	-	-	YcxB-like protein
HHKAHHOL_02201	4.59e-120	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHKAHHOL_02203	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
HHKAHHOL_02204	1.95e-67	-	-	-	-	-	-	-	-
HHKAHHOL_02205	6.77e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
HHKAHHOL_02206	8.28e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HHKAHHOL_02207	0.0	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	permease
HHKAHHOL_02208	7.33e-152	-	-	-	S	-	-	-	membrane
HHKAHHOL_02209	5.05e-104	-	-	-	K	-	-	-	Response regulator of the LytR AlgR family
HHKAHHOL_02210	2.42e-202	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HHKAHHOL_02211	2.42e-254	mtnA	5.3.1.23	-	J	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HHKAHHOL_02212	5.28e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HHKAHHOL_02213	6.55e-292	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02214	0.0	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHKAHHOL_02215	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HHKAHHOL_02216	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HHKAHHOL_02217	1.84e-200	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHKAHHOL_02218	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HHKAHHOL_02219	7.77e-315	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02223	1.65e-113	PaaY	-	-	C	ko:K02617	-	ko00000	Bacterial transferase hexapeptide
HHKAHHOL_02224	3.18e-153	-	-	-	G	-	-	-	Ribose Galactose Isomerase
HHKAHHOL_02225	1.12e-213	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHKAHHOL_02226	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HHKAHHOL_02227	5.52e-241	ccpA	-	-	K	ko:K02529,ko:K03487	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
HHKAHHOL_02228	0.0	-	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
HHKAHHOL_02229	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	D-galactarate dehydratase Altronate hydrolase
HHKAHHOL_02230	9.78e-189	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	PFAM Short-chain dehydrogenase reductase SDR
HHKAHHOL_02231	0.0	-	-	-	G	ko:K02027,ko:K10192	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	extracellular solute-binding
HHKAHHOL_02232	5.21e-183	-	-	-	S	-	-	-	unsaturated rhamnogalacturonyl hydrolase activity
HHKAHHOL_02233	4.8e-223	-	-	-	P	ko:K10193	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02234	7.51e-203	-	-	-	P	ko:K10194	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02235	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HHKAHHOL_02236	1.08e-200	-	-	-	G	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02237	3.83e-147	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02238	1.01e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHKAHHOL_02239	0.0	-	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HHKAHHOL_02240	1.34e-179	-	-	-	J	-	-	-	Acetyltransferase, gnat family
HHKAHHOL_02241	5.4e-164	-	-	-	-	-	-	-	-
HHKAHHOL_02242	1.22e-305	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HHKAHHOL_02243	8.24e-62	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.98
HHKAHHOL_02244	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HHKAHHOL_02245	1.41e-203	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	delta-lactam-biosynthetic de-N-acetylase
HHKAHHOL_02246	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_02247	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HHKAHHOL_02248	1.94e-211	-	-	-	S	-	-	-	EDD domain protein, DegV family
HHKAHHOL_02251	1.02e-261	-	-	-	NU	ko:K02283	-	ko00000,ko02035,ko02044	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
HHKAHHOL_02252	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_02253	7.67e-69	-	-	-	-	-	-	-	-
HHKAHHOL_02257	4.37e-141	-	-	-	-	-	-	-	-
HHKAHHOL_02258	1.52e-172	-	-	-	-	-	-	-	-
HHKAHHOL_02259	0.0	-	-	-	-	-	-	-	-
HHKAHHOL_02260	1.41e-276	-	-	-	M	ko:K03699	-	ko00000,ko02042	Cbs domain
HHKAHHOL_02261	7.36e-304	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHKAHHOL_02262	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	hydrolase, family 3
HHKAHHOL_02263	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHKAHHOL_02264	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HHKAHHOL_02265	1.48e-214	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02266	0.0	cspBA	-	-	O	-	-	-	Belongs to the peptidase S8 family
HHKAHHOL_02267	4.16e-159	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02268	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase, glutamine-hydrolyzing
HHKAHHOL_02270	9.48e-125	-	-	-	K	-	-	-	sequence-specific DNA binding
HHKAHHOL_02271	2.82e-120	-	-	-	-	-	-	-	-
HHKAHHOL_02272	7.42e-164	-	-	-	N	-	-	-	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHKAHHOL_02273	1.82e-90	-	-	-	DZ	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HHKAHHOL_02274	3.06e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHKAHHOL_02275	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHKAHHOL_02276	1.9e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(
HHKAHHOL_02277	1.94e-217	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHKAHHOL_02278	4.53e-213	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HHKAHHOL_02279	2.47e-192	-	-	-	S	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HHKAHHOL_02280	3.48e-52	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HHKAHHOL_02281	1.88e-99	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HHKAHHOL_02282	2.84e-109	-	-	-	KT	-	-	-	response regulator receiver
HHKAHHOL_02284	3.92e-183	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02285	1.02e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02286	1.4e-90	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHKAHHOL_02287	3.65e-198	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02288	3.03e-186	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	PFAM Short-chain dehydrogenase reductase SDR
HHKAHHOL_02289	0.0	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HHKAHHOL_02290	0.0	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HHKAHHOL_02291	1.25e-206	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02292	5.66e-312	-	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	solute-binding protein
HHKAHHOL_02293	3.7e-201	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02294	4.13e-186	-	-	-	P	ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02295	9.74e-19	-	-	-	M	-	-	-	Parallel beta-helix repeats
HHKAHHOL_02296	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HHKAHHOL_02297	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase
HHKAHHOL_02298	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HHKAHHOL_02299	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHKAHHOL_02300	4.73e-141	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	solute-binding protein
HHKAHHOL_02301	6.33e-141	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	solute-binding protein
HHKAHHOL_02302	2.96e-244	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
HHKAHHOL_02303	5.82e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
HHKAHHOL_02304	3.65e-299	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HHKAHHOL_02305	0.0	-	-	-	M	-	-	-	Heparinase II III-like protein
HHKAHHOL_02307	7.18e-145	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02308	4.33e-191	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02309	2.71e-51	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HHKAHHOL_02310	1.1e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHKAHHOL_02311	3.65e-109	-	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
HHKAHHOL_02312	7.24e-39	-	-	-	-	-	-	-	-
HHKAHHOL_02313	9.61e-137	-	-	-	D	ko:K07023	-	ko00000	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02314	0.0	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02315	1.31e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHKAHHOL_02316	2.47e-251	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HHKAHHOL_02317	2.83e-145	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHKAHHOL_02318	6.83e-312	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HHKAHHOL_02319	2.74e-204	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	ornithine carbamoyltransferase
HHKAHHOL_02320	0.0	-	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HHKAHHOL_02321	1.99e-160	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_02322	3.83e-231	-	-	-	S	-	-	-	DHH family
HHKAHHOL_02323	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHKAHHOL_02324	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHKAHHOL_02325	1.8e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_02326	2.88e-250	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HHKAHHOL_02327	2.63e-123	chrA2	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate
HHKAHHOL_02328	2.18e-126	chrA1	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate
HHKAHHOL_02329	3.69e-167	kdpE	-	-	KT	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHKAHHOL_02330	0.0	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HHKAHHOL_02331	5.01e-45	-	-	-	-	-	-	-	-
HHKAHHOL_02332	1.06e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HHKAHHOL_02333	1.22e-306	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HHKAHHOL_02334	4.94e-114	-	-	-	K	ko:K07736	-	ko00000,ko03000	Psort location Cytoplasmic, score
HHKAHHOL_02335	5.3e-302	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02336	2.02e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HHKAHHOL_02337	2.45e-141	-	-	-	J	-	-	-	Acetyltransferase, gnat family
HHKAHHOL_02338	1.63e-175	-	-	-	S	-	-	-	-acetyltransferase
HHKAHHOL_02339	0.0	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHKAHHOL_02340	2.01e-134	-	-	-	K	-	-	-	dihydroxyacetone kinase regulator
HHKAHHOL_02341	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HHKAHHOL_02343	4.18e-38	-	-	-	S	ko:K09790	-	ko00000	Psort location CytoplasmicMembrane, score
HHKAHHOL_02344	1.59e-123	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	glycerol-3-phosphate responsive antiterminator
HHKAHHOL_02345	7.06e-81	-	-	-	S	-	-	-	protein with conserved CXXC pairs
HHKAHHOL_02346	1.81e-309	-	-	-	C	-	-	-	pyridine nucleotide-disulfide oxidoreductase
HHKAHHOL_02347	0.0	-	1.1.5.3	-	P	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HHKAHHOL_02348	1.62e-232	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02349	7.9e-130	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HHKAHHOL_02350	6.5e-33	BT4646	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
HHKAHHOL_02352	3.57e-39	-	-	-	S	-	-	-	Psort location
HHKAHHOL_02353	1.5e-49	-	-	-	L	-	-	-	RelB antitoxin
HHKAHHOL_02354	9.14e-55	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	addiction module toxin, RelE StbE family
HHKAHHOL_02356	3.36e-136	-	-	-	KT	-	-	-	phosphorelay signal transduction system
HHKAHHOL_02357	2.15e-160	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHKAHHOL_02359	1.35e-248	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHKAHHOL_02360	2.26e-265	hisC	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	PFAM Aminotransferase class I and II
HHKAHHOL_02361	0.0	Rnd	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02362	8.53e-309	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02363	2.31e-193	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02364	1.03e-265	-	-	-	-	-	-	-	-
HHKAHHOL_02365	1.17e-50	-	-	-	S	-	-	-	Spore coat associated protein JA (CotJA)
HHKAHHOL_02367	5.55e-149	cotJC	-	-	P	ko:K06334	-	ko00000	PFAM Manganese containing catalase
HHKAHHOL_02368	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HHKAHHOL_02369	1.02e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHKAHHOL_02370	1.7e-81	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_02371	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HHKAHHOL_02372	5.21e-179	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC-type antimicrobial peptide transport system, ATPase component
HHKAHHOL_02373	1.58e-110	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HHKAHHOL_02374	1.14e-98	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HHKAHHOL_02375	8.05e-157	graR	-	-	T	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HHKAHHOL_02376	7.72e-254	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHKAHHOL_02377	1.7e-98	-	-	-	-	-	-	-	-
HHKAHHOL_02378	3.73e-46	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
HHKAHHOL_02379	1.15e-198	-	-	-	V	-	-	-	MatE
HHKAHHOL_02384	6.53e-249	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HHKAHHOL_02385	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_02386	5.41e-227	-	-	-	G	ko:K17213	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HHKAHHOL_02387	1.57e-128	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG3663 G T U mismatch-specific DNA glycosylase
HHKAHHOL_02388	4.62e-92	-	-	-	-	-	-	-	-
HHKAHHOL_02389	2.21e-310	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02390	2.58e-100	-	-	-	-	-	-	-	-
HHKAHHOL_02391	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	domain protein
HHKAHHOL_02392	3.07e-203	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02393	5.61e-293	mccB	2.5.1.48, 4.4.1.8	-	E	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	PFAM Cys Met metabolism
HHKAHHOL_02394	1.53e-209	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHKAHHOL_02395	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHKAHHOL_02396	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02397	1.08e-45	-	-	-	S	ko:K21600	-	ko00000,ko03000	Psort location Cytoplasmic, score
HHKAHHOL_02398	1.25e-145	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, beta subunit
HHKAHHOL_02399	2.14e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHKAHHOL_02400	0.0	cat	-	-	C	-	-	-	PFAM Acetyl-CoA hydrolase transferase
HHKAHHOL_02401	1.34e-258	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HHKAHHOL_02402	5.85e-295	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SMART PUA domain containing protein
HHKAHHOL_02404	4.29e-116	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Protein involved in cell division
HHKAHHOL_02405	1.21e-57	-	-	-	M	-	-	-	Psort location Cellwall, score
HHKAHHOL_02406	3.57e-72	-	-	-	S	-	-	-	COG NOG10998 non supervised orthologous group
HHKAHHOL_02407	8.4e-85	-	-	-	S	-	-	-	COG NOG13239 non supervised orthologous group
HHKAHHOL_02408	3.3e-137	-	-	-	K	-	-	-	helix-turn-helix
HHKAHHOL_02409	1.9e-79	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHKAHHOL_02411	1.4e-190	-	-	-	O	-	-	-	dinitrogenase iron-molybdenum cofactor
HHKAHHOL_02412	9.88e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF4317)
HHKAHHOL_02413	8.63e-157	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	COG3773 Cell wall hydrolyses involved in spore germination
HHKAHHOL_02414	1.63e-247	-	-	-	MT	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC p60 family protein
HHKAHHOL_02415	2.98e-224	-	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HHKAHHOL_02416	0.0	ykpA	-	-	S	-	-	-	ABC transporter
HHKAHHOL_02417	0.0	-	-	-	T	-	-	-	GGDEF domain
HHKAHHOL_02418	1.07e-136	-	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HHKAHHOL_02419	4.14e-138	ttdB	4.2.1.2, 4.2.1.32	-	C	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HHKAHHOL_02420	4.36e-208	-	4.2.1.2, 4.2.1.32	-	C	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Fumarate hydratase (Fumerase)
HHKAHHOL_02421	8.51e-249	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_02422	0.0	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHKAHHOL_02423	4.78e-181	phnE_2	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHKAHHOL_02424	1.95e-182	phnE_1	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphonate ABC transporter, permease protein PhnE
HHKAHHOL_02425	3.38e-173	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHKAHHOL_02426	3.2e-264	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type phosphate phosphonate transport system periplasmic component
HHKAHHOL_02427	1.88e-226	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional
HHKAHHOL_02428	9.17e-99	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02429	1.24e-37	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02430	2.25e-285	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHKAHHOL_02432	9.88e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHKAHHOL_02434	5.23e-204	spoIID	-	-	D	ko:K06381	-	ko00000	stage II sporulation protein D
HHKAHHOL_02435	1.74e-150	-	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
HHKAHHOL_02436	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_02437	0.0	cshA	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HHKAHHOL_02438	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02440	8.87e-66	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHKAHHOL_02442	9.02e-280	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02443	6.76e-106	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HHKAHHOL_02444	8.19e-244	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHKAHHOL_02445	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HHKAHHOL_02446	7.18e-194	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HHKAHHOL_02447	1.73e-126	-	-	-	C	-	-	-	nitroreductase
HHKAHHOL_02448	1e-43	-	-	-	-	-	-	-	-
HHKAHHOL_02449	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HHKAHHOL_02450	4.92e-244	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HHKAHHOL_02451	5.33e-211	-	-	-	K	-	-	-	transcriptional regulator
HHKAHHOL_02452	5.17e-86	-	-	-	P	ko:K07216	-	ko00000	Hemerythrin HHE cation binding domain
HHKAHHOL_02453	1.3e-303	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HHKAHHOL_02454	4.94e-191	surfB1	-	-	M	-	-	-	Cell surface protein
HHKAHHOL_02455	1.1e-311	-	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02456	2.71e-224	-	-	-	K	-	-	-	Transcriptional regulator
HHKAHHOL_02457	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HHKAHHOL_02458	0.0	mepA_2	-	-	V	-	-	-	Mate efflux family protein
HHKAHHOL_02459	0.0	-	-	-	T	-	-	-	PFAM metal-dependent phosphohydrolase, HD sub domain
HHKAHHOL_02460	7.45e-195	-	-	-	E	ko:K06410	-	ko00000	dipicolinic acid synthetase, A subunit
HHKAHHOL_02461	2.76e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Dipicolinic acid synthetase, b subunit
HHKAHHOL_02462	1.4e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02463	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHKAHHOL_02464	1.43e-290	norV	-	-	C	-	-	-	domain protein
HHKAHHOL_02465	4.3e-68	-	-	-	-	-	-	-	-
HHKAHHOL_02466	3.2e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02467	3.17e-126	-	-	-	O	-	-	-	Isoprenylcysteine carboxyl methyltransferase
HHKAHHOL_02468	7.38e-94	-	-	-	-	-	-	-	-
HHKAHHOL_02469	5.96e-127	-	-	-	-	-	-	-	-
HHKAHHOL_02470	7.41e-45	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	PFAM Glyoxalase bleomycin resistance protein dioxygenase
HHKAHHOL_02471	1.02e-62	-	-	-	-	-	-	-	-
HHKAHHOL_02472	3.29e-73	-	-	-	-	-	-	-	-
HHKAHHOL_02473	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHKAHHOL_02474	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHKAHHOL_02475	3.39e-228	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HHKAHHOL_02476	5.24e-187	flgG	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	basal body rod protein
HHKAHHOL_02477	1.43e-183	flgG	-	-	N	ko:K02390,ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	basal body rod protein
HHKAHHOL_02478	2.51e-44	-	-	-	MNO	-	-	-	Flagellar rod assembly protein muramidase FlgJ
HHKAHHOL_02479	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHKAHHOL_02480	1.82e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Abc transporter
HHKAHHOL_02481	1.86e-215	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHKAHHOL_02482	3.64e-222	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HHKAHHOL_02483	4.31e-164	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	ComF family
HHKAHHOL_02484	5.63e-90	yvyF	-	-	N	-	-	-	TIGRFAM flagellar operon protein
HHKAHHOL_02485	1.28e-97	-	-	-	-	-	-	-	-
HHKAHHOL_02486	2.15e-216	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02487	2.12e-200	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHKAHHOL_02488	3.74e-286	-	-	-	S	-	-	-	protein conserved in bacteria
HHKAHHOL_02489	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHKAHHOL_02490	8.42e-55	-	-	-	G	ko:K11189	-	ko00000,ko02000	Psort location Cytoplasmic, score
HHKAHHOL_02491	8.21e-213	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHKAHHOL_02492	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
HHKAHHOL_02493	7.04e-272	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHKAHHOL_02494	2.33e-204	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHKAHHOL_02495	8.25e-142	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHKAHHOL_02496	6.07e-188	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HHKAHHOL_02497	2.1e-306	-	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type polysaccharide polyol phosphate transport system ATPase component
HHKAHHOL_02498	1.01e-122	-	-	-	J	-	-	-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HHKAHHOL_02499	7.12e-161	-	-	-	J	-	-	-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HHKAHHOL_02500	0.0	-	-	-	M	-	-	-	sugar transferase
HHKAHHOL_02501	1.19e-204	wzc	2.7.10.1, 2.7.10.2	-	M	ko:K08252,ko:K08253,ko:K16692	-	ko00000,ko01000,ko01001	capsule polysaccharide biosynthetic process
HHKAHHOL_02502	2.17e-151	-	-	-	-	-	-	-	-
HHKAHHOL_02503	1.57e-131	-	-	-	-	-	-	-	-
HHKAHHOL_02505	8.54e-269	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HHKAHHOL_02506	6.77e-233	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HHKAHHOL_02507	9.47e-247	-	-	-	M	-	-	-	PFAM Glycosyl transferase, group 1
HHKAHHOL_02508	5.46e-206	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HHKAHHOL_02509	1.22e-147	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HHKAHHOL_02510	9.19e-206	-	-	-	S	-	-	-	Glycosyl transferase family 2
HHKAHHOL_02511	2.02e-215	-	-	-	S	-	-	-	Glycosyl transferase family 2
HHKAHHOL_02512	5.61e-60	-	-	-	S	-	-	-	Glycosyltransferase like family
HHKAHHOL_02513	6.73e-100	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HHKAHHOL_02515	8.56e-26	-	-	-	-	-	-	-	-
HHKAHHOL_02518	4.91e-315	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HHKAHHOL_02519	5e-65	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02520	1.36e-114	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02521	1.23e-130	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02522	2.04e-116	-	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HHKAHHOL_02523	3.3e-15	-	-	-	-	-	-	-	-
HHKAHHOL_02524	5.53e-140	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02525	1.18e-169	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02526	4.79e-132	-	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score
HHKAHHOL_02527	5.29e-110	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02528	7.44e-118	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HHKAHHOL_02529	5.6e-24	-	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHKAHHOL_02530	1.02e-165	-	2.4.1.11	GT4	M	ko:K16150	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	PFAM Glycosyl transferase, group 1
HHKAHHOL_02531	8.26e-120	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02532	0.0	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02533	7.52e-45	-	-	-	K	-	-	-	LysR substrate binding domain
HHKAHHOL_02534	8.41e-85	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
HHKAHHOL_02535	0.0	-	1.2.7.1	-	C	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HHKAHHOL_02536	5.74e-269	-	1.2.7.1	-	C	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	oxidoreductase gamma subunit
HHKAHHOL_02537	9.54e-130	-	-	-	P	-	-	-	Citrate transporter
HHKAHHOL_02538	1.24e-187	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHKAHHOL_02542	9.62e-247	ftsK	-	-	I	ko:K03466	-	ko00000,ko03036	transferase activity, transferring acyl groups other than amino-acyl groups
HHKAHHOL_02543	6.29e-290	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHKAHHOL_02544	0.0	-	-	-	T	-	-	-	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHKAHHOL_02546	4.19e-69	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02547	3.22e-290	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HHKAHHOL_02548	0.0	-	-	-	O	-	-	-	Papain family cysteine protease
HHKAHHOL_02549	1.08e-153	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	PFAM cell wall hydrolase autolysin
HHKAHHOL_02550	2.17e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHKAHHOL_02551	2.79e-112	yfcE1	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HHKAHHOL_02552	3.18e-165	-	-	-	N	-	-	-	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHKAHHOL_02553	4.22e-269	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHKAHHOL_02554	2.52e-202	-	-	-	S	-	-	-	Cof-like hydrolase
HHKAHHOL_02555	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	MeTHIonine synthase
HHKAHHOL_02558	5.03e-114	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HHKAHHOL_02559	2.42e-154	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HHKAHHOL_02560	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HHKAHHOL_02561	7.66e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHKAHHOL_02562	1.72e-172	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHKAHHOL_02563	4.8e-140	sigH	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HHKAHHOL_02564	7.61e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HHKAHHOL_02565	1.02e-155	trpF	4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817,ko:K13498,ko:K22100	ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosylanthranilate isomerase activity
HHKAHHOL_02566	1.65e-285	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHKAHHOL_02567	1.57e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHKAHHOL_02568	1.53e-222	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHKAHHOL_02569	4.44e-252	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HHKAHHOL_02570	1.61e-251	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HHKAHHOL_02571	2.23e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HHKAHHOL_02572	1.75e-104	-	-	-	K	ko:K09706	-	ko00000	Protein of unknown function (DUF1284)
HHKAHHOL_02573	2.95e-296	clcA	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
HHKAHHOL_02574	7.8e-42	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HHKAHHOL_02575	9.72e-185	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02577	5.84e-82	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HHKAHHOL_02578	4.34e-131	-	-	-	-	-	-	-	-
HHKAHHOL_02579	1.82e-160	srrA_6	-	-	T	-	-	-	response regulator receiver
HHKAHHOL_02580	0.0	-	2.7.13.3	-	T	ko:K18345	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
HHKAHHOL_02581	3.47e-138	-	-	-	-	-	-	-	-
HHKAHHOL_02582	5.35e-215	cheV	2.7.13.3	-	T	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	response regulator receiver
HHKAHHOL_02583	4.03e-302	-	-	-	-	-	-	-	-
HHKAHHOL_02584	5.54e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHKAHHOL_02585	9.01e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHKAHHOL_02586	5.08e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHKAHHOL_02587	1.4e-147	-	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HHKAHHOL_02588	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHKAHHOL_02589	9.16e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02590	0.0	clpC	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHKAHHOL_02591	0.0	-	-	-	M	-	-	-	Cadherin-like beta sandwich domain
HHKAHHOL_02592	0.0	-	-	-	GT	-	-	-	SH3 domain protein
HHKAHHOL_02594	1.97e-85	-	-	-	S	-	-	-	phosphatase activity
HHKAHHOL_02595	1.13e-115	-	-	-	L	ko:K02315	-	ko00000,ko03032	Bacterial dnaA protein
HHKAHHOL_02596	2.01e-34	-	-	-	S	-	-	-	Transposon-encoded protein TnpW
HHKAHHOL_02597	4.08e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02598	9.53e-56	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HHKAHHOL_02599	1.83e-37	fdx	-	-	C	ko:K05337	-	ko00000	electron transfer activity
HHKAHHOL_02601	3.41e-171	kdpE_1	-	-	KT	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHKAHHOL_02603	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_02605	2.77e-140	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHKAHHOL_02606	1.24e-277	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHKAHHOL_02607	4.01e-44	-	-	-	P	-	-	-	Heavy metal-associated domain protein
HHKAHHOL_02608	1.38e-77	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional regulator
HHKAHHOL_02609	9.44e-82	-	3.1.2.29	-	S	ko:K18700	-	ko00000,ko01000	THIoesterase
HHKAHHOL_02610	2.23e-92	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HHKAHHOL_02611	3.16e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
HHKAHHOL_02612	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HHKAHHOL_02613	3.78e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HHKAHHOL_02614	7.72e-41	-	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HHKAHHOL_02615	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHKAHHOL_02616	1.45e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHKAHHOL_02617	4.99e-291	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHKAHHOL_02618	1.71e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHKAHHOL_02619	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_02620	1.19e-168	srrA_2	-	-	T	-	-	-	response regulator receiver
HHKAHHOL_02621	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHKAHHOL_02622	6.8e-278	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	PDZ DHR GLGF domain protein
HHKAHHOL_02623	3.58e-226	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	domain protein
HHKAHHOL_02624	3.42e-182	ttcA2	-	-	H	-	-	-	Belongs to the TtcA family
HHKAHHOL_02625	1.88e-250	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HHKAHHOL_02626	2.31e-176	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02627	9e-72	-	-	-	M	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HHKAHHOL_02628	3.19e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHKAHHOL_02629	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHKAHHOL_02630	1.31e-139	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Hydrolase, HD family
HHKAHHOL_02631	2.16e-148	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHKAHHOL_02632	7.29e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
HHKAHHOL_02633	6.85e-313	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHKAHHOL_02634	3.28e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HHKAHHOL_02635	5.22e-75	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HHKAHHOL_02636	1.63e-63	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HHKAHHOL_02637	4.86e-302	-	-	-	S	ko:K06320	-	ko00000	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02638	1.28e-293	-	-	-	S	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02639	0.0	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HHKAHHOL_02640	1.58e-65	ogt	-	-	L	-	-	-	6-O-methylguanine DNA methyltransferase, DNA binding domain protein
HHKAHHOL_02641	7.59e-268	-	-	-	M	ko:K00786	-	ko00000,ko01000	PFAM Glycosyl transferase family 2
HHKAHHOL_02642	1.98e-160	-	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHKAHHOL_02644	1.52e-46	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HHKAHHOL_02645	1.01e-57	-	-	-	E	-	-	-	Polysaccharide pyruvyl transferase
HHKAHHOL_02646	4.05e-130	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HHKAHHOL_02647	2.24e-14	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHKAHHOL_02648	2.49e-170	-	-	-	M	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HHKAHHOL_02649	8.95e-84	-	-	-	M	-	-	-	WxcM-like, C-terminal
HHKAHHOL_02650	2.13e-206	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02651	1.44e-209	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02652	8.36e-220	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02653	4.58e-311	-	-	-	H	-	-	-	Methyltransferase domain
HHKAHHOL_02654	2.36e-223	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHKAHHOL_02655	1.23e-274	pseC	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
HHKAHHOL_02656	8.2e-308	-	-	-	S	-	-	-	Glycosyltransferase like family
HHKAHHOL_02657	1.73e-248	pseG	3.6.1.57	-	M	ko:K15897	ko00520,map00520	ko00000,ko00001,ko01000	pseudaminic acid biosynthesis-associated protein PseG
HHKAHHOL_02658	8.57e-248	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	synthase
HHKAHHOL_02659	5.24e-86	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HHKAHHOL_02660	9.89e-248	-	-	-	H	-	-	-	PFAM Glycosyl transferase family 2
HHKAHHOL_02661	3.64e-203	-	-	-	S	-	-	-	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02662	1.21e-58	-	-	-	-	-	-	-	-
HHKAHHOL_02663	3.47e-134	-	-	-	E	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHKAHHOL_02665	1.6e-126	-	-	-	S	-	-	-	Glycosyltransferase like family
HHKAHHOL_02666	8.09e-100	-	-	-	Q	-	-	-	Glycosyltransferase like family
HHKAHHOL_02668	3.9e-157	-	-	-	S	-	-	-	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02669	5.07e-221	-	-	-	S	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02670	2.08e-137	-	-	-	M	-	-	-	Glycosyl transferase family 8
HHKAHHOL_02671	9.91e-12	-	-	-	M	-	-	-	Glycosyl transferase family 8
HHKAHHOL_02672	3.99e-114	neuA	2.7.7.82	-	M	ko:K18431	ko00520,map00520	ko00000,ko00001,ko01000	Cytidylyltransferase
HHKAHHOL_02673	2.69e-167	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHKAHHOL_02674	1.66e-59	-	-	-	S	-	-	-	Glycosyl transferases group 1
HHKAHHOL_02675	1.66e-223	pseB	4.2.1.115	-	M	ko:K15894	ko00520,map00520	ko00000,ko00001,ko01000	Polysaccharide biosynthesis protein
HHKAHHOL_02676	1.19e-114	-	-	-	S	ko:K06320	-	ko00000	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02677	2.39e-208	-	-	-	S	ko:K06320	-	ko00000	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02678	2.08e-208	-	-	-	P	ko:K06320	-	ko00000	DUF based on E. rectale Gene description (DUF3880)
HHKAHHOL_02679	1.17e-132	-	-	-	M	-	-	-	Protein conserved in bacteria
HHKAHHOL_02680	5.77e-220	-	-	-	S	-	-	-	Protein of unknown function DUF115
HHKAHHOL_02682	1.41e-139	-	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHKAHHOL_02683	2.19e-100	-	-	-	-	-	-	-	-
HHKAHHOL_02684	3.05e-82	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein flis
HHKAHHOL_02685	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHKAHHOL_02686	5.18e-89	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	PFAM Flagellar protein FlaG protein
HHKAHHOL_02687	1.35e-42	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHKAHHOL_02688	1.29e-105	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HHKAHHOL_02689	0.0	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HHKAHHOL_02690	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	TIGRFAM Flagellar hook-associated protein, FlgK
HHKAHHOL_02691	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	TIGRFAM Flagellar hook-associated protein, FlgK
HHKAHHOL_02692	1.21e-106	-	-	-	S	-	-	-	FlgN protein
HHKAHHOL_02693	8.8e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Anti-sigma-28 factor, FlgM
HHKAHHOL_02694	1.71e-174	-	-	-	V	-	-	-	vancomycin resistance protein
HHKAHHOL_02695	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_02696	8.89e-164	-	-	-	KT	-	-	-	response regulator receiver
HHKAHHOL_02697	1.59e-157	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HHKAHHOL_02698	6.03e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type metal ion transport system permease component
HHKAHHOL_02699	8.21e-247	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHKAHHOL_02700	7.03e-215	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02701	1.1e-197	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02702	2.09e-91	-	-	-	-	-	-	-	-
HHKAHHOL_02703	3.31e-302	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02704	2.97e-136	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02705	4.6e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHKAHHOL_02706	8.4e-51	-	-	-	E	-	-	-	Binding-protein-dependent transport system inner membrane component
HHKAHHOL_02708	7.14e-166	vanR3	-	-	KT	-	-	-	response regulator receiver
HHKAHHOL_02709	0.0	-	-	-	T	-	-	-	Histidine kinase
HHKAHHOL_02710	1.76e-203	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
HHKAHHOL_02711	0.0	-	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HHKAHHOL_02713	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHKAHHOL_02714	7.42e-232	-	-	-	CP	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02715	4.86e-111	-	-	-	-	-	-	-	-
HHKAHHOL_02717	1.56e-255	-	-	-	T	-	-	-	diguanylate cyclase
HHKAHHOL_02718	4.04e-204	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02719	1.7e-280	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HHKAHHOL_02720	5.63e-187	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHKAHHOL_02721	4.21e-189	-	-	-	G	-	-	-	TIM barrel
HHKAHHOL_02722	1.83e-184	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHKAHHOL_02723	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HHKAHHOL_02724	4.08e-132	-	-	-	G	ko:K02026,ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
HHKAHHOL_02725	9.94e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHKAHHOL_02726	5.53e-242	-	-	-	KT	-	-	-	PFAM Region found in RelA SpoT proteins
HHKAHHOL_02727	3.12e-100	-	-	-	-	-	-	-	-
HHKAHHOL_02728	3.43e-191	-	-	-	Q	-	-	-	Methyltransferase domain protein
HHKAHHOL_02729	2.43e-138	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02730	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HHKAHHOL_02731	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HHKAHHOL_02732	5.98e-208	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHKAHHOL_02733	6.5e-119	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHKAHHOL_02734	0.0	-	-	-	S	-	-	-	TIGR02687 family
HHKAHHOL_02735	1.25e-24	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HHKAHHOL_02736	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	Psort location Cytoplasmic, score
HHKAHHOL_02737	3.73e-116	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HHKAHHOL_02739	2.64e-124	-	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
HHKAHHOL_02740	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction