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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
LEKDDOCD_00001	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
LEKDDOCD_00002	1.7e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
LEKDDOCD_00004	5e-67	-	-	-	K	-	-	-	LysR substrate binding domain
LEKDDOCD_00005	1.17e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
LEKDDOCD_00006	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
LEKDDOCD_00007	1.26e-136	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEKDDOCD_00008	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEKDDOCD_00009	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
LEKDDOCD_00010	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEKDDOCD_00011	1.27e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEKDDOCD_00012	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
LEKDDOCD_00013	5.91e-194	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEKDDOCD_00014	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEKDDOCD_00015	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEKDDOCD_00016	1.05e-59	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
LEKDDOCD_00017	1.13e-82	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEKDDOCD_00018	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEKDDOCD_00019	4.29e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
LEKDDOCD_00020	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
LEKDDOCD_00021	3.2e-81	-	-	-	D	-	-	-	peptidase
LEKDDOCD_00022	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
LEKDDOCD_00023	1.3e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
LEKDDOCD_00025	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEKDDOCD_00026	3.25e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
LEKDDOCD_00027	5.01e-22	yneR	-	-	-	-	-	-	-
LEKDDOCD_00028	7.19e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEKDDOCD_00029	7.54e-284	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
LEKDDOCD_00030	3.16e-126	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
LEKDDOCD_00031	6.05e-191	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
LEKDDOCD_00032	1.12e-11	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_00033	8.94e-141	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
LEKDDOCD_00034	3.74e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
LEKDDOCD_00035	6.27e-90	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEKDDOCD_00036	4.69e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
LEKDDOCD_00037	1.3e-277	pepF	-	-	E	-	-	-	Oligopeptidase F
LEKDDOCD_00038	2.04e-137	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEKDDOCD_00039	2.01e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
LEKDDOCD_00040	4.63e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
LEKDDOCD_00041	2.06e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
LEKDDOCD_00042	2.51e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
LEKDDOCD_00044	7.47e-217	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
LEKDDOCD_00045	4.68e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
LEKDDOCD_00046	3.56e-268	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_00047	1.11e-286	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
LEKDDOCD_00049	6.62e-106	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
LEKDDOCD_00051	4.07e-135	yxeH	-	-	S	-	-	-	hydrolase
LEKDDOCD_00052	2.53e-146	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
LEKDDOCD_00053	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
LEKDDOCD_00054	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEKDDOCD_00055	5.35e-126	yycH	-	-	S	-	-	-	YycH protein
LEKDDOCD_00056	2.73e-99	yycI	-	-	S	-	-	-	YycH protein
LEKDDOCD_00057	9.56e-22	-	-	-	S	-	-	-	YjbR
LEKDDOCD_00058	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
LEKDDOCD_00059	2.33e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
LEKDDOCD_00060	2.75e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEKDDOCD_00061	8.25e-262	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
LEKDDOCD_00062	4.19e-176	-	-	-	S	-	-	-	interspecies interaction between organisms
LEKDDOCD_00063	2.74e-63	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
LEKDDOCD_00064	3.88e-92	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
LEKDDOCD_00067	6.57e-186	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
LEKDDOCD_00068	3.31e-189	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
LEKDDOCD_00069	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEKDDOCD_00070	1.5e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
LEKDDOCD_00071	1.08e-251	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
LEKDDOCD_00072	3.77e-35	-	-	-	-	-	-	-	-
LEKDDOCD_00073	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
LEKDDOCD_00074	4.09e-77	-	-	-	T	-	-	-	Universal stress protein family
LEKDDOCD_00076	3.13e-271	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEKDDOCD_00077	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
LEKDDOCD_00078	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
LEKDDOCD_00079	1.17e-90	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
LEKDDOCD_00080	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
LEKDDOCD_00081	5.14e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
LEKDDOCD_00082	4.35e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
LEKDDOCD_00083	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
LEKDDOCD_00084	7.19e-139	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
LEKDDOCD_00085	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
LEKDDOCD_00086	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEKDDOCD_00087	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
LEKDDOCD_00088	6.97e-47	-	-	-	-	-	-	-	-
LEKDDOCD_00089	7.3e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
LEKDDOCD_00090	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEKDDOCD_00091	4.23e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
LEKDDOCD_00092	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
LEKDDOCD_00093	2.46e-130	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
LEKDDOCD_00094	1.88e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
LEKDDOCD_00095	8.26e-36	adhR	-	-	K	-	-	-	transcriptional regulator
LEKDDOCD_00096	5.43e-88	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKDDOCD_00098	3.52e-191	-	-	-	EGP	-	-	-	Major Facilitator
LEKDDOCD_00099	2.08e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
LEKDDOCD_00100	1.85e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
LEKDDOCD_00101	1.3e-47	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEKDDOCD_00102	2.33e-147	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
LEKDDOCD_00103	5.83e-75	-	-	-	S	-	-	-	Glycosyltransferase like family 2
LEKDDOCD_00104	5.28e-107	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00105	9.02e-124	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
LEKDDOCD_00106	1.95e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00107	7.98e-90	-	-	-	S	-	-	-	Glycosyltransferase like family 2
LEKDDOCD_00108	1.2e-184	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEKDDOCD_00109	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEKDDOCD_00110	1.55e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEKDDOCD_00111	2.32e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEKDDOCD_00112	8.69e-32	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
LEKDDOCD_00113	4.02e-89	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
LEKDDOCD_00114	4.71e-106	-	-	-	S	-	-	-	Glycosyl transferase family 2
LEKDDOCD_00115	2.44e-180	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEKDDOCD_00116	9.12e-87	-	-	-	M	-	-	-	Glycosyl transferase family 2
LEKDDOCD_00117	4.84e-51	-	-	-	M	-	-	-	Glycosyltransferase family 92
LEKDDOCD_00118	5.61e-123	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEKDDOCD_00119	1.7e-23	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
LEKDDOCD_00120	1.15e-30	cotSA	-	-	M	ko:K06338	-	ko00000	Spore coat protein
LEKDDOCD_00121	2.2e-12	-	-	-	S	-	-	-	EpsG family
LEKDDOCD_00122	2.39e-81	-	-	-	M	-	-	-	Glycosyl transferase family 2
LEKDDOCD_00123	1.85e-121	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
LEKDDOCD_00124	2.58e-08	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEKDDOCD_00125	2.85e-57	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEKDDOCD_00127	1.71e-271	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
LEKDDOCD_00128	2.84e-98	epsB	-	-	M	-	-	-	biosynthesis protein
LEKDDOCD_00129	1.56e-117	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
LEKDDOCD_00130	5.99e-142	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
LEKDDOCD_00131	1.15e-162	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEKDDOCD_00132	2.93e-116	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
LEKDDOCD_00133	8.02e-81	-	-	-	-	-	-	-	-
LEKDDOCD_00134	8.39e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEKDDOCD_00135	4.39e-139	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
LEKDDOCD_00136	4.08e-118	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
LEKDDOCD_00137	2.12e-134	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00138	2.01e-247	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
LEKDDOCD_00139	1e-235	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
LEKDDOCD_00140	3.58e-81	-	-	-	D	-	-	-	Peptidase family M23
LEKDDOCD_00142	7.74e-172	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
LEKDDOCD_00143	2.3e-102	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
LEKDDOCD_00144	1.32e-74	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
LEKDDOCD_00145	1.29e-146	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEKDDOCD_00146	1.62e-185	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
LEKDDOCD_00147	3.88e-215	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
LEKDDOCD_00150	6.15e-14	-	-	-	-	-	-	-	-
LEKDDOCD_00151	3.98e-116	yeeC	-	-	P	-	-	-	T5orf172
LEKDDOCD_00152	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
LEKDDOCD_00153	2.29e-288	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
LEKDDOCD_00154	9.43e-70	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
LEKDDOCD_00155	2.81e-82	-	-	-	-	-	-	-	-
LEKDDOCD_00156	1.09e-78	-	-	-	-	-	-	-	-
LEKDDOCD_00157	1.74e-201	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
LEKDDOCD_00159	2.18e-63	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
LEKDDOCD_00161	5.71e-136	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEKDDOCD_00163	1.17e-239	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00165	7.51e-140	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LEKDDOCD_00166	1.42e-276	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
LEKDDOCD_00167	8.21e-53	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
LEKDDOCD_00168	1.09e-273	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEKDDOCD_00169	6.67e-239	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
LEKDDOCD_00170	8.74e-92	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
LEKDDOCD_00171	3.18e-64	-	-	-	S	-	-	-	Membrane
LEKDDOCD_00172	1.35e-230	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
LEKDDOCD_00173	1.31e-71	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
LEKDDOCD_00175	5.69e-133	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
LEKDDOCD_00177	3.52e-287	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
LEKDDOCD_00178	1.61e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
LEKDDOCD_00179	1.28e-60	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEKDDOCD_00180	1.91e-88	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEKDDOCD_00181	5.09e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
LEKDDOCD_00183	1.06e-51	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEKDDOCD_00184	1.36e-47	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
LEKDDOCD_00185	1.78e-234	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
LEKDDOCD_00186	1.18e-150	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
LEKDDOCD_00187	7.62e-217	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
LEKDDOCD_00188	2.39e-114	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEKDDOCD_00189	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEKDDOCD_00190	1.91e-287	fusA1	-	-	J	-	-	-	elongation factor G
LEKDDOCD_00191	1.06e-34	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEKDDOCD_00192	5.75e-09	-	-	-	-	-	-	-	-
LEKDDOCD_00193	3.32e-271	potE	-	-	E	-	-	-	Amino Acid
LEKDDOCD_00194	1.31e-45	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
LEKDDOCD_00195	2.33e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
LEKDDOCD_00196	5.09e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEKDDOCD_00197	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LEKDDOCD_00198	2.9e-114	nanK	-	-	GK	-	-	-	ROK family
LEKDDOCD_00199	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
LEKDDOCD_00200	2.14e-81	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
LEKDDOCD_00201	1.63e-193	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEKDDOCD_00202	1.02e-259	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEKDDOCD_00203	7.38e-94	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
LEKDDOCD_00204	2.12e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEKDDOCD_00205	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
LEKDDOCD_00206	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
LEKDDOCD_00207	6.56e-103	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
LEKDDOCD_00208	4.68e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEKDDOCD_00215	4.15e-69	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
LEKDDOCD_00216	3.32e-63	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
LEKDDOCD_00222	2.44e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
LEKDDOCD_00223	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
LEKDDOCD_00224	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
LEKDDOCD_00225	8.7e-121	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
LEKDDOCD_00226	3.79e-118	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
LEKDDOCD_00227	1.14e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
LEKDDOCD_00228	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEKDDOCD_00229	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
LEKDDOCD_00230	4.57e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
LEKDDOCD_00231	3.13e-239	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
LEKDDOCD_00232	7e-124	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
LEKDDOCD_00236	5.05e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
LEKDDOCD_00237	3.06e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
LEKDDOCD_00238	1.12e-121	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
LEKDDOCD_00239	3.19e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
LEKDDOCD_00240	9.45e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEKDDOCD_00241	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
LEKDDOCD_00242	4.81e-54	-	-	-	S	-	-	-	VanZ like family
LEKDDOCD_00243	1.54e-203	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
LEKDDOCD_00244	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
LEKDDOCD_00246	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEKDDOCD_00248	3.43e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEKDDOCD_00249	2.89e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEKDDOCD_00250	5.92e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
LEKDDOCD_00251	7.98e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
LEKDDOCD_00252	2.71e-107	-	-	-	S	-	-	-	membrane
LEKDDOCD_00253	1.39e-100	-	-	-	S	-	-	-	VIT family
LEKDDOCD_00254	3.48e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
LEKDDOCD_00255	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
LEKDDOCD_00256	1.3e-148	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEKDDOCD_00257	4.32e-146	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEKDDOCD_00258	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
LEKDDOCD_00259	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
LEKDDOCD_00260	3.06e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
LEKDDOCD_00261	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
LEKDDOCD_00262	3.54e-288	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
LEKDDOCD_00263	2.13e-84	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
LEKDDOCD_00264	1.53e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEKDDOCD_00265	6.21e-274	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
LEKDDOCD_00266	8.7e-147	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
LEKDDOCD_00269	2.64e-75	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
LEKDDOCD_00271	8.41e-296	-	-	-	S	-	-	-	COG0433 Predicted ATPase
LEKDDOCD_00272	3.91e-54	-	-	-	-	-	-	-	-
LEKDDOCD_00275	4.02e-169	-	-	-	NU	-	-	-	StbA protein
LEKDDOCD_00276	6.1e-110	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
LEKDDOCD_00277	1.16e-29	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
LEKDDOCD_00289	4.04e-55	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
LEKDDOCD_00291	1.44e-67	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
LEKDDOCD_00292	1.73e-33	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEKDDOCD_00295	3.95e-54	-	-	-	M	-	-	-	hmm tigr01076
LEKDDOCD_00296	6.6e-99	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
LEKDDOCD_00300	6.88e-78	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
LEKDDOCD_00301	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
LEKDDOCD_00303	6.2e-13	-	-	-	S	-	-	-	Fic/DOC family
LEKDDOCD_00304	3.53e-28	-	-	-	S	-	-	-	Fic/DOC family
LEKDDOCD_00305	1.32e-98	-	-	-	S	-	-	-	Fic/DOC family
LEKDDOCD_00306	1.58e-220	-	-	-	L	-	-	-	PLD-like domain
LEKDDOCD_00309	1.32e-141	-	-	-	L	-	-	-	Initiator Replication protein
LEKDDOCD_00310	9.55e-46	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
LEKDDOCD_00311	1.55e-183	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEKDDOCD_00312	4.38e-54	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEKDDOCD_00313	4.59e-289	-	-	-	L	-	-	-	Probable transposase
LEKDDOCD_00314	2.08e-33	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEKDDOCD_00315	2.11e-15	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
LEKDDOCD_00316	4.21e-10	bglG	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
LEKDDOCD_00317	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
LEKDDOCD_00319	1.27e-46	-	-	-	-	-	-	-	-
LEKDDOCD_00320	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
LEKDDOCD_00321	5.13e-55	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
LEKDDOCD_00322	3.7e-24	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
LEKDDOCD_00324	7.21e-54	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
LEKDDOCD_00325	1.01e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
LEKDDOCD_00326	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
LEKDDOCD_00327	3e-199	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
LEKDDOCD_00328	6.14e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
LEKDDOCD_00329	1.51e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
LEKDDOCD_00334	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEKDDOCD_00335	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEKDDOCD_00337	1.96e-59	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEKDDOCD_00338	3.91e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEKDDOCD_00339	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEKDDOCD_00340	3.86e-271	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
LEKDDOCD_00341	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
LEKDDOCD_00342	1.41e-106	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
LEKDDOCD_00343	2.6e-114	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
LEKDDOCD_00344	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
LEKDDOCD_00345	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
LEKDDOCD_00346	8.48e-48	-	-	-	M	-	-	-	LysM domain
LEKDDOCD_00347	2.32e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
LEKDDOCD_00348	1.84e-244	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
LEKDDOCD_00349	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
LEKDDOCD_00350	1.09e-253	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEKDDOCD_00351	4.93e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
LEKDDOCD_00352	4.59e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEKDDOCD_00353	1.41e-133	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
LEKDDOCD_00354	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
LEKDDOCD_00355	6.76e-181	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
LEKDDOCD_00356	1.13e-17	-	-	-	T	-	-	-	diguanylate cyclase
LEKDDOCD_00357	4.55e-162	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEKDDOCD_00358	8.88e-236	-	-	-	-	-	-	-	-
LEKDDOCD_00359	1.48e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
LEKDDOCD_00360	1.21e-255	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
LEKDDOCD_00361	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
LEKDDOCD_00362	1.87e-152	-	-	-	T	-	-	-	diguanylate cyclase activity
LEKDDOCD_00363	3.04e-37	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
LEKDDOCD_00364	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
LEKDDOCD_00365	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
LEKDDOCD_00366	1.1e-78	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEKDDOCD_00367	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
LEKDDOCD_00368	1.93e-69	-	-	-	S	-	-	-	Membrane
LEKDDOCD_00369	7.32e-81	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
LEKDDOCD_00371	4.56e-266	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
LEKDDOCD_00372	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
LEKDDOCD_00373	8.93e-237	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEKDDOCD_00374	2.25e-77	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEKDDOCD_00375	7.12e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
LEKDDOCD_00376	6.45e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
LEKDDOCD_00377	3.87e-82	-	-	-	-	-	-	-	-
LEKDDOCD_00378	3.4e-225	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
LEKDDOCD_00379	8.24e-53	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEKDDOCD_00380	3.14e-59	-	-	-	M	-	-	-	Chain length determinant protein
LEKDDOCD_00381	6.61e-83	-	-	-	D	-	-	-	AAA domain
LEKDDOCD_00382	5.59e-273	capD	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00383	7.48e-211	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
LEKDDOCD_00384	4.18e-98	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
LEKDDOCD_00385	2.02e-52	-	-	-	S	ko:K13006,ko:K19429	-	ko00000,ko01000,ko01005	Bacterial transferase hexapeptide (six repeats)
LEKDDOCD_00386	1.4e-153	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEKDDOCD_00387	1.35e-101	-	-	-	M	-	-	-	glycosyl transferase group 1
LEKDDOCD_00388	2.38e-83	-	-	-	M	-	-	-	Glycosyltransferase Family 4
LEKDDOCD_00389	3.92e-50	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase
LEKDDOCD_00390	2.36e-72	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEKDDOCD_00392	2.03e-28	-	-	-	-	-	-	-	-
LEKDDOCD_00394	1.89e-144	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEKDDOCD_00395	7.86e-146	-	-	-	S	-	-	-	Glycosyltransferase WbsX
LEKDDOCD_00396	3.75e-126	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_00397	1.78e-182	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
LEKDDOCD_00398	2.02e-224	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEKDDOCD_00399	1.36e-85	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEKDDOCD_00400	5.85e-87	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEKDDOCD_00401	1.78e-13	-	-	-	-	-	-	-	-
LEKDDOCD_00402	1.01e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
LEKDDOCD_00403	2.19e-54	ywnA	-	-	K	-	-	-	Transcriptional regulator
LEKDDOCD_00404	9.96e-41	-	-	-	S	-	-	-	CHY zinc finger
LEKDDOCD_00405	1.32e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
LEKDDOCD_00407	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
LEKDDOCD_00408	4.47e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
LEKDDOCD_00410	3.92e-52	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
LEKDDOCD_00411	3.26e-93	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
LEKDDOCD_00412	1.05e-82	-	-	-	H	-	-	-	Methyltransferase domain
LEKDDOCD_00418	2.1e-53	-	-	-	L	-	-	-	PFAM HNH endonuclease
LEKDDOCD_00421	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
LEKDDOCD_00422	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
LEKDDOCD_00423	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
LEKDDOCD_00424	1.21e-20	-	-	-	-	-	-	-	-
LEKDDOCD_00426	5.56e-89	-	-	-	-	-	-	-	-
LEKDDOCD_00427	1.18e-125	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
LEKDDOCD_00428	4.46e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
LEKDDOCD_00429	5.15e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
LEKDDOCD_00430	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEKDDOCD_00431	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEKDDOCD_00432	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEKDDOCD_00433	3.93e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEKDDOCD_00434	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEKDDOCD_00435	1.14e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEKDDOCD_00436	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEKDDOCD_00437	1.16e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
LEKDDOCD_00438	1.77e-158	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
LEKDDOCD_00439	2.42e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
LEKDDOCD_00440	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
LEKDDOCD_00441	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEKDDOCD_00442	3.75e-237	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
LEKDDOCD_00443	2.16e-81	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
LEKDDOCD_00444	1.38e-244	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
LEKDDOCD_00445	8.33e-13	-	-	-	D	-	-	-	Antitoxin Phd_YefM, type II toxin-antitoxin system
LEKDDOCD_00446	5.57e-12	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
LEKDDOCD_00448	6.85e-93	-	-	-	M	-	-	-	GNAT acetyltransferase
LEKDDOCD_00449	9.45e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEKDDOCD_00450	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
LEKDDOCD_00451	3.41e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
LEKDDOCD_00453	3.42e-89	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEKDDOCD_00454	2.02e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
LEKDDOCD_00455	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
LEKDDOCD_00456	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
LEKDDOCD_00457	2.7e-265	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEKDDOCD_00458	2.18e-236	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEKDDOCD_00460	1.58e-109	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEKDDOCD_00461	3.3e-52	-	-	-	-	-	-	-	-
LEKDDOCD_00462	7.93e-152	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
LEKDDOCD_00463	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
LEKDDOCD_00464	6.24e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
LEKDDOCD_00465	1.5e-79	-	-	-	S	-	-	-	Helix-turn-helix domain
LEKDDOCD_00466	1.14e-156	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
LEKDDOCD_00467	1.12e-15	-	-	-	M	-	-	-	Lysin motif
LEKDDOCD_00468	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
LEKDDOCD_00469	2.09e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
LEKDDOCD_00470	2.07e-196	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
LEKDDOCD_00471	4.01e-87	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEKDDOCD_00472	5.92e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
LEKDDOCD_00473	1.33e-198	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEKDDOCD_00474	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
LEKDDOCD_00476	4.37e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEKDDOCD_00477	1.12e-221	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
LEKDDOCD_00478	2.74e-39	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEKDDOCD_00479	2.34e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEKDDOCD_00480	4.07e-77	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
LEKDDOCD_00481	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
LEKDDOCD_00482	1.17e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
LEKDDOCD_00483	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEKDDOCD_00485	2.01e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
LEKDDOCD_00486	1.4e-141	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
LEKDDOCD_00487	3.32e-105	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
LEKDDOCD_00488	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
LEKDDOCD_00489	8.71e-100	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
LEKDDOCD_00490	2.15e-235	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEKDDOCD_00491	4.83e-53	-	-	-	S	-	-	-	ASCH
LEKDDOCD_00492	3.19e-90	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
LEKDDOCD_00493	3.81e-63	-	-	-	S	-	-	-	EDD domain protein, DegV family
LEKDDOCD_00494	1.21e-64	-	-	-	S	-	-	-	EDD domain protein, DegV family
LEKDDOCD_00495	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
LEKDDOCD_00496	2.69e-253	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
LEKDDOCD_00497	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEKDDOCD_00498	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEKDDOCD_00499	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEKDDOCD_00500	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
LEKDDOCD_00502	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
LEKDDOCD_00503	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEKDDOCD_00504	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
LEKDDOCD_00505	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
LEKDDOCD_00506	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEKDDOCD_00507	3.26e-255	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEKDDOCD_00508	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
LEKDDOCD_00509	2.34e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
LEKDDOCD_00510	8.87e-120	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEKDDOCD_00512	1.47e-105	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
LEKDDOCD_00513	2e-164	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEKDDOCD_00514	6.67e-221	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
LEKDDOCD_00515	8.77e-174	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
LEKDDOCD_00516	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEKDDOCD_00517	1.05e-254	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
LEKDDOCD_00518	3.9e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
LEKDDOCD_00519	2.44e-174	-	-	-	EG	-	-	-	EamA-like transporter family
LEKDDOCD_00520	1.2e-90	-	-	-	L	-	-	-	DNA alkylation repair enzyme
LEKDDOCD_00521	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
LEKDDOCD_00522	1.15e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEKDDOCD_00523	9.72e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
LEKDDOCD_00524	2.37e-184	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
LEKDDOCD_00525	4.43e-09	-	-	-	D	-	-	-	nuclear chromosome segregation
LEKDDOCD_00530	8.73e-51	-	-	-	-	-	-	-	-
LEKDDOCD_00531	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
LEKDDOCD_00532	1.03e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
LEKDDOCD_00533	8.9e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
LEKDDOCD_00534	3.81e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
LEKDDOCD_00535	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEKDDOCD_00537	2.01e-110	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
LEKDDOCD_00538	4.96e-219	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEKDDOCD_00539	5.73e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEKDDOCD_00540	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
LEKDDOCD_00541	1.34e-172	-	-	-	K	-	-	-	Transcriptional regulator
LEKDDOCD_00542	1.43e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEKDDOCD_00543	1.5e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEKDDOCD_00544	7.36e-238	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
LEKDDOCD_00545	1.05e-140	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEKDDOCD_00546	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
LEKDDOCD_00547	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEKDDOCD_00548	3.4e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEKDDOCD_00549	9.43e-57	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEKDDOCD_00550	1.03e-71	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
LEKDDOCD_00551	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEKDDOCD_00552	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEKDDOCD_00553	2.15e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEKDDOCD_00554	1.53e-149	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
LEKDDOCD_00555	6.01e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
LEKDDOCD_00556	1.24e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
LEKDDOCD_00557	5.6e-17	-	-	-	-	-	-	-	-
LEKDDOCD_00558	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEKDDOCD_00559	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
LEKDDOCD_00560	2.31e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEKDDOCD_00561	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEKDDOCD_00562	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEKDDOCD_00563	2.8e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
LEKDDOCD_00564	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKDDOCD_00565	6.62e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEKDDOCD_00569	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEKDDOCD_00570	5.21e-55	-	-	-	S	-	-	-	repeat protein
LEKDDOCD_00571	1.45e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
LEKDDOCD_00572	3.21e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
LEKDDOCD_00573	2.1e-41	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEKDDOCD_00574	2.72e-110	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEKDDOCD_00575	1.09e-79	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
LEKDDOCD_00576	8.44e-78	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
LEKDDOCD_00577	6.65e-89	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
LEKDDOCD_00578	7.13e-36	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
LEKDDOCD_00579	1.41e-252	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
LEKDDOCD_00580	3.35e-42	-	-	-	S	-	-	-	Pfam:DUF2276
LEKDDOCD_00581	7.32e-192	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
LEKDDOCD_00582	6.67e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
LEKDDOCD_00583	1.42e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEKDDOCD_00584	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEKDDOCD_00585	3.94e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
LEKDDOCD_00586	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEKDDOCD_00587	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEKDDOCD_00588	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
LEKDDOCD_00589	7.98e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
LEKDDOCD_00590	2.64e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEKDDOCD_00592	1.06e-141	ydhF	-	-	S	-	-	-	Aldo keto reductase
LEKDDOCD_00593	9.1e-32	-	-	-	K	-	-	-	regulatory protein
LEKDDOCD_00594	8.46e-170	-	-	-	C	-	-	-	Aldo keto reductase
LEKDDOCD_00595	2.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEKDDOCD_00596	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEKDDOCD_00597	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_00598	5.86e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEKDDOCD_00599	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEKDDOCD_00600	1.33e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKDDOCD_00601	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
LEKDDOCD_00603	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
LEKDDOCD_00604	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
LEKDDOCD_00605	3.6e-149	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEKDDOCD_00608	7.62e-127	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEKDDOCD_00609	1.49e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
LEKDDOCD_00610	1.68e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEKDDOCD_00611	3.06e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKDDOCD_00612	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEKDDOCD_00613	1.71e-105	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEKDDOCD_00614	2.93e-71	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
LEKDDOCD_00615	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
LEKDDOCD_00616	1.05e-179	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
LEKDDOCD_00617	1.55e-45	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
LEKDDOCD_00618	1.56e-275	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
LEKDDOCD_00619	2.23e-120	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
LEKDDOCD_00620	5.1e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
LEKDDOCD_00621	2.3e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
LEKDDOCD_00622	3.76e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEKDDOCD_00623	1.79e-134	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
LEKDDOCD_00624	1.56e-187	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
LEKDDOCD_00625	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
LEKDDOCD_00626	3.64e-63	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
LEKDDOCD_00627	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
LEKDDOCD_00628	2.81e-74	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
LEKDDOCD_00629	6.94e-28	-	-	-	-	-	-	-	-
LEKDDOCD_00631	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
LEKDDOCD_00632	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEKDDOCD_00633	3.68e-136	-	-	-	S	-	-	-	Acyltransferase family
LEKDDOCD_00634	5.32e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
LEKDDOCD_00635	3.31e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
LEKDDOCD_00636	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEKDDOCD_00637	1.99e-174	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
LEKDDOCD_00638	6.13e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEKDDOCD_00639	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKDDOCD_00640	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKDDOCD_00641	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEKDDOCD_00642	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
LEKDDOCD_00643	5.17e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
LEKDDOCD_00644	1.36e-64	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEKDDOCD_00645	8.3e-93	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
LEKDDOCD_00646	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
LEKDDOCD_00647	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEKDDOCD_00648	2.48e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
LEKDDOCD_00649	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
LEKDDOCD_00650	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
LEKDDOCD_00651	1.09e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
LEKDDOCD_00652	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
LEKDDOCD_00653	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
LEKDDOCD_00654	3.42e-31	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
LEKDDOCD_00655	1.34e-22	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
LEKDDOCD_00656	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEKDDOCD_00657	3.51e-33	-	-	-	-	-	-	-	-
LEKDDOCD_00658	1.72e-29	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
LEKDDOCD_00659	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEKDDOCD_00660	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEKDDOCD_00661	3.67e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEKDDOCD_00662	4.78e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEKDDOCD_00663	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEKDDOCD_00664	0.000361	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEKDDOCD_00665	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEKDDOCD_00666	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEKDDOCD_00667	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEKDDOCD_00668	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
LEKDDOCD_00669	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEKDDOCD_00670	6.81e-248	-	-	-	E	ko:K03294	-	ko00000	amino acid
LEKDDOCD_00671	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
LEKDDOCD_00672	6.45e-144	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
LEKDDOCD_00673	3.22e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEKDDOCD_00674	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
LEKDDOCD_00675	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
LEKDDOCD_00676	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEKDDOCD_00677	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEKDDOCD_00678	1.59e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEKDDOCD_00679	2.32e-295	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
LEKDDOCD_00680	7.23e-130	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEKDDOCD_00681	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEKDDOCD_00682	1.54e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEKDDOCD_00683	1.35e-306	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEKDDOCD_00684	2.1e-303	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
LEKDDOCD_00685	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
LEKDDOCD_00686	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
LEKDDOCD_00687	1.08e-118	tnp2	-	-	L	-	-	-	Transposase
LEKDDOCD_00688	3.74e-74	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
LEKDDOCD_00689	1.61e-144	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEKDDOCD_00690	9.86e-239	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
LEKDDOCD_00691	1.11e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
LEKDDOCD_00692	1.77e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEKDDOCD_00693	1.09e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEKDDOCD_00694	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEKDDOCD_00695	2.16e-152	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEKDDOCD_00696	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEKDDOCD_00697	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
LEKDDOCD_00698	2.19e-119	-	-	-	M	-	-	-	Phosphotransferase enzyme family
LEKDDOCD_00699	6.94e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
LEKDDOCD_00700	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
LEKDDOCD_00701	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
LEKDDOCD_00702	6.55e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
LEKDDOCD_00703	6.92e-215	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
LEKDDOCD_00704	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEKDDOCD_00705	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
LEKDDOCD_00706	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
LEKDDOCD_00707	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEKDDOCD_00708	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEKDDOCD_00709	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEKDDOCD_00710	6.95e-75	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEKDDOCD_00711	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEKDDOCD_00712	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEKDDOCD_00713	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
LEKDDOCD_00714	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEKDDOCD_00715	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEKDDOCD_00716	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEKDDOCD_00717	1.47e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEKDDOCD_00718	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
LEKDDOCD_00719	2.09e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
LEKDDOCD_00720	6.58e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
LEKDDOCD_00721	2.91e-138	ampC	-	-	V	-	-	-	Beta-lactamase
LEKDDOCD_00722	1.83e-41	-	-	-	-	-	-	-	-
LEKDDOCD_00723	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_00724	7.05e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEKDDOCD_00726	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEKDDOCD_00727	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEKDDOCD_00728	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
LEKDDOCD_00729	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEKDDOCD_00730	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEKDDOCD_00731	5.22e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
LEKDDOCD_00732	4.07e-152	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEKDDOCD_00733	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEKDDOCD_00734	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEKDDOCD_00735	4.38e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
LEKDDOCD_00736	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
LEKDDOCD_00737	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
LEKDDOCD_00738	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
LEKDDOCD_00739	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEKDDOCD_00740	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEKDDOCD_00741	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
LEKDDOCD_00742	1.58e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
LEKDDOCD_00743	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEKDDOCD_00744	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEKDDOCD_00745	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
LEKDDOCD_00746	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
LEKDDOCD_00747	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEKDDOCD_00749	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
LEKDDOCD_00750	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
LEKDDOCD_00751	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
LEKDDOCD_00752	4.97e-140	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEKDDOCD_00753	3.58e-23	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
LEKDDOCD_00754	1.69e-59	yqhL	-	-	P	-	-	-	Rhodanese-like protein
LEKDDOCD_00755	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
LEKDDOCD_00756	1.74e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
LEKDDOCD_00757	9.08e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
LEKDDOCD_00758	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEKDDOCD_00759	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEKDDOCD_00761	3.62e-88	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
LEKDDOCD_00762	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
LEKDDOCD_00763	1.38e-119	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
LEKDDOCD_00764	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
LEKDDOCD_00765	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
LEKDDOCD_00766	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEKDDOCD_00767	1.17e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
LEKDDOCD_00768	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
LEKDDOCD_00769	1.27e-153	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
LEKDDOCD_00770	4.39e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEKDDOCD_00771	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEKDDOCD_00772	1.15e-181	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEKDDOCD_00773	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEKDDOCD_00774	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEKDDOCD_00775	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
LEKDDOCD_00776	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEKDDOCD_00777	2.06e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
LEKDDOCD_00778	3.98e-148	-	-	-	-	-	-	-	-
LEKDDOCD_00779	4.27e-143	-	-	-	-	-	-	-	-
LEKDDOCD_00780	4.75e-170	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
LEKDDOCD_00781	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
LEKDDOCD_00782	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEKDDOCD_00783	1.09e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEKDDOCD_00784	1.46e-141	csrR	-	-	K	-	-	-	response regulator
LEKDDOCD_00786	4.68e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEKDDOCD_00787	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEKDDOCD_00788	3.15e-200	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEKDDOCD_00789	1.89e-75	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEKDDOCD_00790	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
LEKDDOCD_00791	1.82e-49	-	-	-	-	-	-	-	-
LEKDDOCD_00792	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEKDDOCD_00793	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
LEKDDOCD_00794	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
LEKDDOCD_00795	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
LEKDDOCD_00796	3.48e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
LEKDDOCD_00797	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
LEKDDOCD_00798	9.11e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
LEKDDOCD_00799	3.99e-154	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
LEKDDOCD_00800	1.13e-104	-	-	-	H	-	-	-	Nodulation protein S (NodS)
LEKDDOCD_00801	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEKDDOCD_00802	3.8e-88	yqeK	-	-	H	-	-	-	Hydrolase, HD family
LEKDDOCD_00803	7.07e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEKDDOCD_00804	9.56e-41	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
LEKDDOCD_00805	1.46e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
LEKDDOCD_00806	1.92e-90	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
LEKDDOCD_00807	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEKDDOCD_00808	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
LEKDDOCD_00809	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEKDDOCD_00810	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEKDDOCD_00811	1.63e-136	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
LEKDDOCD_00812	6.94e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
LEKDDOCD_00813	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEKDDOCD_00814	7.54e-63	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEKDDOCD_00815	8.5e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEKDDOCD_00816	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEKDDOCD_00817	6.41e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
LEKDDOCD_00818	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
LEKDDOCD_00819	1.24e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
LEKDDOCD_00820	5.61e-300	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEKDDOCD_00821	6.12e-98	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEKDDOCD_00822	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
LEKDDOCD_00823	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEKDDOCD_00824	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
LEKDDOCD_00825	2.24e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_00826	1.16e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_00827	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
LEKDDOCD_00829	7.01e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEKDDOCD_00830	4.62e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEKDDOCD_00831	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
LEKDDOCD_00832	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
LEKDDOCD_00834	4.59e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
LEKDDOCD_00835	1.42e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEKDDOCD_00836	9.83e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEKDDOCD_00837	2.26e-59	ykuL	-	-	S	-	-	-	CBS domain
LEKDDOCD_00838	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
LEKDDOCD_00839	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEKDDOCD_00840	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
LEKDDOCD_00841	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEKDDOCD_00842	2.1e-139	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
LEKDDOCD_00843	3e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
LEKDDOCD_00844	1.9e-159	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEKDDOCD_00845	5.08e-275	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
LEKDDOCD_00846	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEKDDOCD_00847	1.16e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEKDDOCD_00848	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEKDDOCD_00849	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
LEKDDOCD_00850	1.21e-130	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
LEKDDOCD_00851	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEKDDOCD_00852	2.45e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEKDDOCD_00853	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
LEKDDOCD_00854	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEKDDOCD_00855	2.43e-48	-	-	-	-	-	-	-	-
LEKDDOCD_00858	4.1e-82	-	-	-	S	-	-	-	LlaJI restriction endonuclease
LEKDDOCD_00859	1.28e-105	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
LEKDDOCD_00861	6.36e-268	dam	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
LEKDDOCD_00862	2.17e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
LEKDDOCD_00863	6.3e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEKDDOCD_00864	4.36e-79	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEKDDOCD_00865	9.88e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
LEKDDOCD_00866	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
LEKDDOCD_00867	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
LEKDDOCD_00868	3.67e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEKDDOCD_00888	1.06e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
LEKDDOCD_00889	1.64e-102	-	-	-	-	-	-	-	-
LEKDDOCD_00891	1.61e-90	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
LEKDDOCD_00892	2.6e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEKDDOCD_00893	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEKDDOCD_00894	2.28e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
LEKDDOCD_00895	9.9e-105	ylmH	-	-	S	-	-	-	S4 domain protein
LEKDDOCD_00896	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
LEKDDOCD_00897	1.15e-42	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEKDDOCD_00898	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEKDDOCD_00899	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEKDDOCD_00900	6.44e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEKDDOCD_00901	6.08e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEKDDOCD_00902	7.31e-234	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEKDDOCD_00903	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEKDDOCD_00904	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEKDDOCD_00905	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
LEKDDOCD_00906	3.67e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEKDDOCD_00907	5.35e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
LEKDDOCD_00909	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
LEKDDOCD_00910	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
LEKDDOCD_00911	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
LEKDDOCD_00912	3.24e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
LEKDDOCD_00913	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_00914	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
LEKDDOCD_00915	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
LEKDDOCD_00916	3.56e-98	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEKDDOCD_00917	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
LEKDDOCD_00918	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
LEKDDOCD_00919	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
LEKDDOCD_00920	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
LEKDDOCD_00921	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
LEKDDOCD_00922	8.51e-170	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
LEKDDOCD_00923	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEKDDOCD_00924	1.01e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEKDDOCD_00925	1.45e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
LEKDDOCD_00926	2.45e-225	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEKDDOCD_00927	9e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
LEKDDOCD_00928	6.88e-129	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEKDDOCD_00929	6.66e-30	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
LEKDDOCD_00930	6.66e-247	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
LEKDDOCD_00932	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
LEKDDOCD_00933	1.31e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
LEKDDOCD_00934	2.99e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
LEKDDOCD_00935	2.95e-158	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
LEKDDOCD_00938	1.03e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
LEKDDOCD_00939	3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
LEKDDOCD_00940	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEKDDOCD_00941	0.0	-	-	-	S	-	-	-	membrane
LEKDDOCD_00942	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEKDDOCD_00943	2.04e-267	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
LEKDDOCD_00944	1.68e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
LEKDDOCD_00945	1.24e-178	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEKDDOCD_00947	1.68e-22	-	-	-	-	-	-	-	-
LEKDDOCD_00948	7.25e-255	oatA	-	-	I	-	-	-	Acyltransferase
LEKDDOCD_00949	1.16e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEKDDOCD_00950	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEKDDOCD_00951	1.21e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKDDOCD_00954	1.47e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
LEKDDOCD_00955	1.79e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEKDDOCD_00956	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
LEKDDOCD_00957	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
LEKDDOCD_00958	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEKDDOCD_00959	5.44e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
LEKDDOCD_00960	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEKDDOCD_00961	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
LEKDDOCD_00962	6.38e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEKDDOCD_00963	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
LEKDDOCD_00964	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEKDDOCD_00965	2.13e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEKDDOCD_00966	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
LEKDDOCD_00967	3.5e-18	-	-	-	-	-	-	-	-
LEKDDOCD_00968	5.55e-184	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEKDDOCD_00969	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
LEKDDOCD_00970	8.18e-310	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
LEKDDOCD_00971	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
LEKDDOCD_00972	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
LEKDDOCD_00974	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
LEKDDOCD_00976	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
LEKDDOCD_00977	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEKDDOCD_00978	2.88e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEKDDOCD_00979	7.18e-194	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEKDDOCD_00980	1.54e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEKDDOCD_00981	4.02e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEKDDOCD_00982	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEKDDOCD_00983	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
LEKDDOCD_00984	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEKDDOCD_00985	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEKDDOCD_00986	1.06e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
LEKDDOCD_00987	5.2e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEKDDOCD_00988	3.17e-187	ymfH	-	-	S	-	-	-	Peptidase M16
LEKDDOCD_00989	1.04e-136	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
LEKDDOCD_00990	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEKDDOCD_00991	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEKDDOCD_00992	5e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
LEKDDOCD_00993	2.89e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
LEKDDOCD_00994	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEKDDOCD_00995	3.47e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEKDDOCD_00996	1.17e-23	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
LEKDDOCD_00997	1.53e-163	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
LEKDDOCD_00998	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
LEKDDOCD_00999	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEKDDOCD_01000	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
LEKDDOCD_01001	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEKDDOCD_01002	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
LEKDDOCD_01003	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
LEKDDOCD_01004	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
LEKDDOCD_01005	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
LEKDDOCD_01006	4.05e-180	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
LEKDDOCD_01007	2.16e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEKDDOCD_01008	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEKDDOCD_01009	1.37e-53	-	-	-	-	-	-	-	-
LEKDDOCD_01010	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEKDDOCD_01011	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEKDDOCD_01012	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
LEKDDOCD_01013	4.45e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
LEKDDOCD_01014	5.39e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
LEKDDOCD_01015	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
LEKDDOCD_01016	1.95e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
LEKDDOCD_01017	3.5e-168	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEKDDOCD_01018	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEKDDOCD_01019	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEKDDOCD_01020	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
LEKDDOCD_01021	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEKDDOCD_01022	2.76e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
LEKDDOCD_01024	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEKDDOCD_01025	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
LEKDDOCD_01026	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
LEKDDOCD_01027	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
LEKDDOCD_01028	5.61e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
LEKDDOCD_01029	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEKDDOCD_01030	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEKDDOCD_01031	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEKDDOCD_01032	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEKDDOCD_01033	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEKDDOCD_01034	7.14e-169	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEKDDOCD_01035	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
LEKDDOCD_01036	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
LEKDDOCD_01037	2.62e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEKDDOCD_01038	2.08e-110	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
LEKDDOCD_01039	4.95e-81	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
LEKDDOCD_01040	2.63e-206	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEKDDOCD_01041	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEKDDOCD_01042	1.38e-119	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
LEKDDOCD_01043	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEKDDOCD_01044	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
LEKDDOCD_01045	3.04e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
LEKDDOCD_01046	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
LEKDDOCD_01047	0.0	ydaO	-	-	E	-	-	-	amino acid
LEKDDOCD_01048	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
LEKDDOCD_01049	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEKDDOCD_01050	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEKDDOCD_01051	2.85e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEKDDOCD_01052	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEKDDOCD_01053	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
LEKDDOCD_01054	2.51e-206	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEKDDOCD_01055	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEKDDOCD_01056	3.7e-88	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
LEKDDOCD_01057	1.15e-177	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
LEKDDOCD_01058	6.03e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
LEKDDOCD_01059	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEKDDOCD_01060	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
LEKDDOCD_01061	4.64e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
LEKDDOCD_01062	2.18e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEKDDOCD_01063	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
LEKDDOCD_01064	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEKDDOCD_01065	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEKDDOCD_01066	1.8e-266	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEKDDOCD_01067	3.69e-79	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEKDDOCD_01068	2.25e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
LEKDDOCD_01069	1.36e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
LEKDDOCD_01070	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
LEKDDOCD_01071	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEKDDOCD_01072	1.56e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEKDDOCD_01073	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEKDDOCD_01074	1.04e-70	-	-	-	-	-	-	-	-
LEKDDOCD_01075	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEKDDOCD_01076	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEKDDOCD_01077	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEKDDOCD_01078	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEKDDOCD_01079	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
LEKDDOCD_01080	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEKDDOCD_01081	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEKDDOCD_01082	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
LEKDDOCD_01083	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEKDDOCD_01084	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEKDDOCD_01085	1.3e-262	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
LEKDDOCD_01086	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEKDDOCD_01087	1.38e-195	yacL	-	-	S	-	-	-	domain protein
LEKDDOCD_01088	1.14e-283	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEKDDOCD_01089	2.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
LEKDDOCD_01090	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
LEKDDOCD_01091	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
LEKDDOCD_01092	3.93e-45	-	-	-	S	-	-	-	Enterocin A Immunity
LEKDDOCD_01093	1.67e-108	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEKDDOCD_01094	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
LEKDDOCD_01095	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEKDDOCD_01097	7.99e-55	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
LEKDDOCD_01098	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
LEKDDOCD_01099	3.08e-164	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEKDDOCD_01100	1.79e-306	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEKDDOCD_01101	8.17e-114	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEKDDOCD_01102	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
LEKDDOCD_01103	3.69e-116	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEKDDOCD_01106	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
LEKDDOCD_01116	2.79e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
LEKDDOCD_01117	5.35e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEKDDOCD_01118	7.87e-199	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEKDDOCD_01119	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
LEKDDOCD_01120	6.07e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEKDDOCD_01122	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
LEKDDOCD_01123	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEKDDOCD_01124	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKDDOCD_01125	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKDDOCD_01126	4.06e-30	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
LEKDDOCD_01127	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEKDDOCD_01128	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEKDDOCD_01129	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEKDDOCD_01130	3.29e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEKDDOCD_01131	2.45e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
LEKDDOCD_01132	1.21e-145	vanR	-	-	K	-	-	-	response regulator
LEKDDOCD_01133	8.71e-190	hpk31	-	-	T	-	-	-	Histidine kinase
LEKDDOCD_01134	8.34e-113	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
LEKDDOCD_01135	9.14e-187	-	-	-	G	-	-	-	Transporter, major facilitator family protein
LEKDDOCD_01136	3.86e-278	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEKDDOCD_01137	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01138	4.44e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_01139	9.3e-280	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01140	6.78e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
LEKDDOCD_01141	1.29e-11	-	-	-	-	-	-	-	-
LEKDDOCD_01142	1.85e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
LEKDDOCD_01143	1.2e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
LEKDDOCD_01144	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
LEKDDOCD_01145	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
LEKDDOCD_01147	0.0	-	-	-	L	-	-	-	DNA helicase
LEKDDOCD_01148	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEKDDOCD_01149	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
LEKDDOCD_01150	1.13e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
LEKDDOCD_01151	6.4e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
LEKDDOCD_01152	6.39e-131	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_01153	4.78e-41	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_01154	1.33e-55	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
LEKDDOCD_01155	1.25e-189	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
LEKDDOCD_01156	5.58e-163	-	-	-	-	-	-	-	-
LEKDDOCD_01157	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEKDDOCD_01158	9.88e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
LEKDDOCD_01159	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEKDDOCD_01160	4.61e-170	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEKDDOCD_01161	5.45e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
LEKDDOCD_01162	7.69e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
LEKDDOCD_01163	7.82e-171	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
LEKDDOCD_01164	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
LEKDDOCD_01165	2.07e-147	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEKDDOCD_01166	5.52e-196	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
LEKDDOCD_01167	2.74e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
LEKDDOCD_01168	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEKDDOCD_01169	2.34e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEKDDOCD_01170	3.16e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKDDOCD_01171	9.41e-142	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
LEKDDOCD_01174	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEKDDOCD_01175	7.27e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
LEKDDOCD_01176	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
LEKDDOCD_01177	2.43e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
LEKDDOCD_01178	1.37e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEKDDOCD_01179	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEKDDOCD_01180	3.2e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEKDDOCD_01182	6.77e-140	dkgB	-	-	S	-	-	-	reductase
LEKDDOCD_01183	1.82e-33	-	-	-	-	-	-	-	-
LEKDDOCD_01184	7.94e-99	-	-	-	F	-	-	-	Phosphorylase superfamily
LEKDDOCD_01185	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
LEKDDOCD_01186	6.04e-80	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
LEKDDOCD_01187	1.64e-122	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEKDDOCD_01188	4.53e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
LEKDDOCD_01189	4.73e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
LEKDDOCD_01191	4.66e-62	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
LEKDDOCD_01193	7.85e-27	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
LEKDDOCD_01195	6.62e-91	-	-	-	-	-	-	-	-
LEKDDOCD_01196	1.99e-16	-	-	-	-	-	-	-	-
LEKDDOCD_01197	1.06e-132	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
LEKDDOCD_01198	3.53e-111	-	-	-	S	-	-	-	hydrolase
LEKDDOCD_01199	8.48e-262	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
LEKDDOCD_01200	1.65e-108	-	-	-	F	-	-	-	glutamine amidotransferase
LEKDDOCD_01201	2.81e-33	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
LEKDDOCD_01202	1.75e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEKDDOCD_01203	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEKDDOCD_01205	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEKDDOCD_01206	1.93e-240	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEKDDOCD_01207	2.05e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
LEKDDOCD_01208	6.42e-79	-	-	-	-	-	-	-	-
LEKDDOCD_01209	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
LEKDDOCD_01211	6.13e-100	-	-	-	S	-	-	-	Cell surface protein
LEKDDOCD_01213	2.89e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
LEKDDOCD_01214	1.54e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
LEKDDOCD_01215	1.15e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEKDDOCD_01216	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEKDDOCD_01217	9.69e-54	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
LEKDDOCD_01218	4.94e-198	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
LEKDDOCD_01219	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEKDDOCD_01220	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEKDDOCD_01222	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
LEKDDOCD_01223	1.84e-116	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
LEKDDOCD_01224	8.08e-197	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
LEKDDOCD_01225	7.32e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEKDDOCD_01226	5.84e-75	-	-	-	-	-	-	-	-
LEKDDOCD_01227	7.8e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
LEKDDOCD_01228	3.16e-30	-	-	-	S	-	-	-	Cytochrome B5
LEKDDOCD_01230	3.19e-79	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
LEKDDOCD_01231	2.59e-150	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEKDDOCD_01232	3.09e-20	-	-	-	K	-	-	-	Transcriptional regulator, Cro CI family
LEKDDOCD_01234	5.71e-57	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
LEKDDOCD_01239	1.81e-26	-	-	-	-	-	-	-	-
LEKDDOCD_01241	1.79e-41	-	-	-	L	-	-	-	DnaD domain protein
LEKDDOCD_01244	7.74e-243	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEKDDOCD_01245	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
LEKDDOCD_01246	1e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
LEKDDOCD_01247	3.12e-200	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
LEKDDOCD_01248	3.95e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEKDDOCD_01249	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEKDDOCD_01250	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
LEKDDOCD_01251	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
LEKDDOCD_01252	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
LEKDDOCD_01253	4.34e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEKDDOCD_01254	3.62e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEKDDOCD_01255	9.91e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
LEKDDOCD_01256	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
LEKDDOCD_01257	2.32e-131	-	-	-	G	-	-	-	MucBP domain
LEKDDOCD_01258	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
LEKDDOCD_01259	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
LEKDDOCD_01260	1.5e-22	-	-	-	-	-	-	-	-
LEKDDOCD_01261	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
LEKDDOCD_01262	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEKDDOCD_01263	1.8e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
LEKDDOCD_01264	1.3e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
LEKDDOCD_01265	3.57e-165	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEKDDOCD_01266	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
LEKDDOCD_01267	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEKDDOCD_01277	1.79e-268	potE	-	-	E	-	-	-	Amino Acid
LEKDDOCD_01278	1.41e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01279	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01280	9.44e-55	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEKDDOCD_01281	2.25e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
LEKDDOCD_01282	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
LEKDDOCD_01283	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEKDDOCD_01284	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEKDDOCD_01285	6.05e-118	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEKDDOCD_01286	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
LEKDDOCD_01287	5.09e-197	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
LEKDDOCD_01288	6.04e-67	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
LEKDDOCD_01289	1.23e-184	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
LEKDDOCD_01290	3.88e-58	cps3I	-	-	G	-	-	-	Acyltransferase family
LEKDDOCD_01291	4.55e-20	-	-	-	-	-	-	-	-
LEKDDOCD_01294	2.37e-92	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
LEKDDOCD_01295	1.14e-192	XK27_08315	-	-	M	-	-	-	Sulfatase
LEKDDOCD_01296	1.65e-75	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEKDDOCD_01298	1.45e-115	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEKDDOCD_01299	4.21e-223	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
LEKDDOCD_01300	1.48e-161	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEKDDOCD_01301	2.07e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
LEKDDOCD_01302	9.34e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEKDDOCD_01303	4.19e-68	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
LEKDDOCD_01305	2.38e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
LEKDDOCD_01306	1.2e-315	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
LEKDDOCD_01307	1.18e-107	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
LEKDDOCD_01308	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEKDDOCD_01309	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
LEKDDOCD_01310	3.43e-106	pncA	-	-	Q	-	-	-	isochorismatase
LEKDDOCD_01311	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
LEKDDOCD_01312	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
LEKDDOCD_01313	9.49e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEKDDOCD_01314	1.4e-54	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
LEKDDOCD_01315	5.43e-209	-	-	-	C	-	-	-	Luciferase-like monooxygenase
LEKDDOCD_01316	2.21e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
LEKDDOCD_01317	6.89e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
LEKDDOCD_01318	6.46e-98	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
LEKDDOCD_01319	4.18e-76	-	-	-	EG	-	-	-	EamA-like transporter family
LEKDDOCD_01320	3.2e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
LEKDDOCD_01321	1.1e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
LEKDDOCD_01322	8.68e-159	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEKDDOCD_01323	2.89e-74	-	-	-	K	-	-	-	WYL domain
LEKDDOCD_01324	2.73e-08	-	-	-	S	-	-	-	Mor transcription activator family
LEKDDOCD_01330	0.000274	-	-	-	S	-	-	-	zinc-ribbon domain
LEKDDOCD_01331	4.78e-144	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
LEKDDOCD_01332	8.83e-164	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
LEKDDOCD_01333	1.81e-24	-	-	-	-	-	-	-	-
LEKDDOCD_01334	1.78e-132	-	-	-	E	-	-	-	AzlC protein
LEKDDOCD_01335	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
LEKDDOCD_01336	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
LEKDDOCD_01337	3.21e-24	-	-	-	-	-	-	-	-
LEKDDOCD_01338	9.17e-75	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
LEKDDOCD_01339	1.19e-28	-	-	-	-	-	-	-	-
LEKDDOCD_01340	3.07e-119	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEKDDOCD_01341	1.45e-114	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
LEKDDOCD_01342	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
LEKDDOCD_01343	1.93e-103	-	-	-	S	-	-	-	Putative threonine/serine exporter
LEKDDOCD_01344	1.19e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
LEKDDOCD_01345	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEKDDOCD_01346	1.48e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEKDDOCD_01347	2.25e-45	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
LEKDDOCD_01348	3.11e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEKDDOCD_01349	4.13e-29	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEKDDOCD_01350	5.34e-83	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
LEKDDOCD_01352	3.13e-68	ccl	-	-	S	-	-	-	QueT transporter
LEKDDOCD_01353	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
LEKDDOCD_01354	2.59e-130	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEKDDOCD_01355	4.34e-138	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
LEKDDOCD_01356	3.68e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEKDDOCD_01357	5.27e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEKDDOCD_01358	5.52e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
LEKDDOCD_01359	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKDDOCD_01360	2.8e-174	-	-	-	V	-	-	-	MatE
LEKDDOCD_01361	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
LEKDDOCD_01362	5.65e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEKDDOCD_01363	1.13e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_01364	1.13e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
LEKDDOCD_01365	3.6e-94	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
LEKDDOCD_01366	3.15e-32	-	-	-	-	-	-	-	-
LEKDDOCD_01367	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
LEKDDOCD_01368	8.78e-102	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
LEKDDOCD_01369	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
LEKDDOCD_01370	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEKDDOCD_01371	8.72e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
LEKDDOCD_01372	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
LEKDDOCD_01373	1.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
LEKDDOCD_01374	6.38e-123	-	-	-	-	-	-	-	-
LEKDDOCD_01375	6.62e-19	-	-	-	-	-	-	-	-
LEKDDOCD_01376	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01377	9.76e-126	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEKDDOCD_01378	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01379	9.34e-105	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01380	1.17e-239	steT	-	-	E	ko:K03294	-	ko00000	amino acid
LEKDDOCD_01381	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEKDDOCD_01382	1.68e-187	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
LEKDDOCD_01383	3.76e-67	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LEKDDOCD_01384	1.07e-100	-	-	-	K	-	-	-	rpiR family
LEKDDOCD_01385	4.93e-217	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEKDDOCD_01386	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
LEKDDOCD_01387	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEKDDOCD_01388	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
LEKDDOCD_01389	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEKDDOCD_01390	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEKDDOCD_01391	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEKDDOCD_01392	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEKDDOCD_01393	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEKDDOCD_01394	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEKDDOCD_01395	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
LEKDDOCD_01396	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEKDDOCD_01397	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEKDDOCD_01398	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEKDDOCD_01399	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEKDDOCD_01400	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEKDDOCD_01401	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEKDDOCD_01402	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEKDDOCD_01403	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEKDDOCD_01404	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEKDDOCD_01405	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
LEKDDOCD_01406	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
LEKDDOCD_01407	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEKDDOCD_01408	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEKDDOCD_01409	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEKDDOCD_01410	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
LEKDDOCD_01411	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEKDDOCD_01412	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEKDDOCD_01413	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEKDDOCD_01414	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
LEKDDOCD_01415	3.22e-127	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKDDOCD_01416	6.17e-140	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKDDOCD_01417	1.08e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEKDDOCD_01418	3.6e-159	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEKDDOCD_01419	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEKDDOCD_01420	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
LEKDDOCD_01422	4e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
LEKDDOCD_01423	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEKDDOCD_01424	1.03e-85	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
LEKDDOCD_01425	1.81e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01426	1.62e-139	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01427	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
LEKDDOCD_01428	3.17e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LEKDDOCD_01429	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
LEKDDOCD_01430	8.4e-66	-	-	-	M	-	-	-	LysM domain protein
LEKDDOCD_01431	5.05e-143	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEKDDOCD_01432	3.35e-132	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
LEKDDOCD_01433	8.18e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
LEKDDOCD_01434	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
LEKDDOCD_01435	4.09e-261	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEKDDOCD_01436	1.8e-179	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEKDDOCD_01437	1.09e-110	-	-	-	S	-	-	-	(CBS) domain
LEKDDOCD_01438	1.16e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
LEKDDOCD_01439	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEKDDOCD_01440	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEKDDOCD_01441	5.76e-174	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
LEKDDOCD_01442	2.59e-41	yabO	-	-	J	-	-	-	S4 domain protein
LEKDDOCD_01443	1.49e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
LEKDDOCD_01444	4.1e-61	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
LEKDDOCD_01445	4.16e-117	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEKDDOCD_01446	3.54e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
LEKDDOCD_01447	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEKDDOCD_01448	4.6e-167	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEKDDOCD_01449	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEKDDOCD_01450	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
LEKDDOCD_01451	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
LEKDDOCD_01452	3e-94	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
LEKDDOCD_01454	8.86e-84	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
LEKDDOCD_01455	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
LEKDDOCD_01456	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEKDDOCD_01457	5e-45	-	-	-	-	-	-	-	-
LEKDDOCD_01458	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEKDDOCD_01459	2.46e-198	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEKDDOCD_01460	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEKDDOCD_01461	2e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
LEKDDOCD_01462	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
LEKDDOCD_01464	1.09e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01465	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
LEKDDOCD_01466	2.44e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
LEKDDOCD_01467	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEKDDOCD_01468	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
LEKDDOCD_01469	9.09e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
LEKDDOCD_01470	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
LEKDDOCD_01471	4.77e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
LEKDDOCD_01472	7.11e-129	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01473	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEKDDOCD_01475	1.3e-58	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
LEKDDOCD_01476	1.01e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEKDDOCD_01477	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEKDDOCD_01478	1.65e-259	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
LEKDDOCD_01479	2.67e-218	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
LEKDDOCD_01480	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
LEKDDOCD_01481	4.88e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
LEKDDOCD_01482	2.82e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
LEKDDOCD_01483	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
LEKDDOCD_01484	2.56e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
LEKDDOCD_01485	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_01486	8.29e-264	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
LEKDDOCD_01488	1.33e-140	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
LEKDDOCD_01489	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
LEKDDOCD_01490	1.53e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
LEKDDOCD_01491	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
LEKDDOCD_01492	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
LEKDDOCD_01493	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
LEKDDOCD_01494	1.13e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
LEKDDOCD_01495	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
LEKDDOCD_01496	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
LEKDDOCD_01497	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEKDDOCD_01498	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
LEKDDOCD_01499	1.12e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
LEKDDOCD_01500	2.5e-59	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
LEKDDOCD_01501	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
LEKDDOCD_01502	7.86e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
LEKDDOCD_01504	8.87e-88	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
LEKDDOCD_01505	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
LEKDDOCD_01506	3.95e-54	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
LEKDDOCD_01508	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01509	8.17e-123	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01510	9.01e-42	tetR	-	-	K	-	-	-	transcriptional regulator
LEKDDOCD_01512	5.37e-45	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKDDOCD_01513	3.31e-282	-	-	-	L	-	-	-	Probable transposase
LEKDDOCD_01514	1.04e-34	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKDDOCD_01515	1.41e-155	ytbE	-	-	S	-	-	-	reductase
LEKDDOCD_01516	3.49e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
LEKDDOCD_01517	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
LEKDDOCD_01518	3.37e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_01519	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
LEKDDOCD_01520	1.6e-68	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEKDDOCD_01521	2.06e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
LEKDDOCD_01522	4.63e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
LEKDDOCD_01523	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
LEKDDOCD_01525	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
LEKDDOCD_01526	5.63e-146	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
LEKDDOCD_01527	2.36e-265	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEKDDOCD_01528	6.55e-22	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
LEKDDOCD_01529	6.96e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEKDDOCD_01530	2.46e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEKDDOCD_01531	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEKDDOCD_01532	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEKDDOCD_01533	2.51e-253	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
LEKDDOCD_01534	7.54e-278	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
LEKDDOCD_01535	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEKDDOCD_01536	1.76e-71	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
LEKDDOCD_01537	3.17e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
LEKDDOCD_01538	2.01e-315	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
LEKDDOCD_01539	4.15e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
LEKDDOCD_01540	1.05e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
LEKDDOCD_01541	4.12e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
LEKDDOCD_01542	9.65e-230	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
LEKDDOCD_01543	2.85e-146	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
LEKDDOCD_01544	9.75e-30	-	-	-	K	-	-	-	transcriptional regulator
LEKDDOCD_01545	6.9e-96	-	-	-	S	-	-	-	intracellular protease amidase
LEKDDOCD_01546	3.4e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
LEKDDOCD_01547	2.45e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
LEKDDOCD_01548	1.45e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
LEKDDOCD_01549	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
LEKDDOCD_01550	1.68e-157	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
LEKDDOCD_01551	7.67e-139	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
LEKDDOCD_01552	1.32e-84	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
LEKDDOCD_01553	1.66e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
LEKDDOCD_01554	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEKDDOCD_01555	6.91e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
LEKDDOCD_01556	5.93e-148	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
LEKDDOCD_01557	1.09e-243	-	-	-	C	-	-	-	FMN_bind
LEKDDOCD_01558	2.26e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
LEKDDOCD_01559	1.27e-203	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
LEKDDOCD_01560	1.2e-248	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LEKDDOCD_01561	4.01e-93	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
LEKDDOCD_01562	3.69e-166	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
LEKDDOCD_01563	4.52e-127	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
LEKDDOCD_01564	1.27e-103	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
LEKDDOCD_01565	7.94e-14	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
LEKDDOCD_01566	6.98e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
LEKDDOCD_01567	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEKDDOCD_01569	2.03e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEKDDOCD_01570	3.42e-82	-	-	-	C	-	-	-	FMN binding
LEKDDOCD_01571	3.56e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
LEKDDOCD_01572	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
LEKDDOCD_01573	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
LEKDDOCD_01578	2.4e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
LEKDDOCD_01579	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
LEKDDOCD_01580	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
LEKDDOCD_01581	3.37e-16	epsJ2	-	-	S	-	-	-	Glycosyltransferase like family 2
LEKDDOCD_01582	4.02e-28	-	-	-	-	-	-	-	-
LEKDDOCD_01583	4.53e-112	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
LEKDDOCD_01584	5.42e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
LEKDDOCD_01585	2.6e-230	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
LEKDDOCD_01586	1.08e-115	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEKDDOCD_01587	3.96e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
LEKDDOCD_01588	3.33e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
LEKDDOCD_01589	5.6e-39	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEKDDOCD_01590	1.42e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
LEKDDOCD_01591	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
LEKDDOCD_01592	5.01e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
LEKDDOCD_01593	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEKDDOCD_01594	5.71e-88	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
LEKDDOCD_01595	5.17e-149	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
LEKDDOCD_01596	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
LEKDDOCD_01597	5.38e-121	baeS	-	-	T	-	-	-	Histidine kinase
LEKDDOCD_01598	3.8e-102	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
LEKDDOCD_01599	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
LEKDDOCD_01600	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
LEKDDOCD_01601	8.07e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
LEKDDOCD_01602	7.96e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
LEKDDOCD_01603	2.15e-93	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
LEKDDOCD_01604	9.15e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
LEKDDOCD_01605	1.16e-08	hmpP2	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
LEKDDOCD_01606	4.41e-105	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEKDDOCD_01607	2.72e-90	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
LEKDDOCD_01608	4.75e-163	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEKDDOCD_01609	4.17e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEKDDOCD_01610	1.36e-96	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
LEKDDOCD_01611	2.22e-44	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
LEKDDOCD_01612	1.03e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
LEKDDOCD_01613	3.42e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
LEKDDOCD_01614	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
LEKDDOCD_01615	1.58e-15	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
LEKDDOCD_01617	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEKDDOCD_01618	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
LEKDDOCD_01619	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
LEKDDOCD_01620	6.33e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEKDDOCD_01621	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01622	3.11e-133	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEKDDOCD_01623	1.19e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEKDDOCD_01624	7.9e-169	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_01625	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
LEKDDOCD_01626	8.15e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEKDDOCD_01627	2.89e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
LEKDDOCD_01628	9.35e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEKDDOCD_01629	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEKDDOCD_01630	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEKDDOCD_01631	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
LEKDDOCD_01632	4.1e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEKDDOCD_01633	5.18e-61	-	-	-	C	-	-	-	Flavodoxin
LEKDDOCD_01634	6.56e-73	yphH	-	-	S	-	-	-	Cupin domain
LEKDDOCD_01635	5.1e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
LEKDDOCD_01636	1.02e-177	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
LEKDDOCD_01637	6.31e-137	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
LEKDDOCD_01638	5.34e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEKDDOCD_01639	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01640	3.22e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
LEKDDOCD_01641	2.84e-107	-	-	-	C	-	-	-	nitroreductase
LEKDDOCD_01642	4.37e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
LEKDDOCD_01643	2.34e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
LEKDDOCD_01644	1.29e-215	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEKDDOCD_01645	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
LEKDDOCD_01647	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEKDDOCD_01648	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
LEKDDOCD_01649	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
LEKDDOCD_01650	1.15e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
LEKDDOCD_01652	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
LEKDDOCD_01653	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
LEKDDOCD_01654	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
LEKDDOCD_01655	2.22e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEKDDOCD_01656	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
LEKDDOCD_01657	9.52e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
LEKDDOCD_01658	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
LEKDDOCD_01659	4.91e-79	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
LEKDDOCD_01660	1.78e-17	-	-	-	-	-	-	-	-
LEKDDOCD_01661	5.41e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
LEKDDOCD_01662	3.25e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
LEKDDOCD_01663	1.39e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
LEKDDOCD_01664	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LEKDDOCD_01665	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
LEKDDOCD_01666	2.33e-57	cps3F	-	-	-	-	-	-	-
LEKDDOCD_01667	2.22e-108	-	-	-	S	-	-	-	Membrane
LEKDDOCD_01668	0.0	-	-	-	E	-	-	-	Amino acid permease
LEKDDOCD_01669	1.03e-292	cadA	-	-	P	-	-	-	P-type ATPase
LEKDDOCD_01670	3.51e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
LEKDDOCD_01671	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
LEKDDOCD_01672	1.18e-69	-	-	-	F	-	-	-	glutamine amidotransferase
LEKDDOCD_01673	3.36e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
LEKDDOCD_01674	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEKDDOCD_01675	4.22e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEKDDOCD_01676	4.8e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
LEKDDOCD_01677	2.05e-208	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
LEKDDOCD_01678	8.89e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEKDDOCD_01679	1.04e-284	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
LEKDDOCD_01680	9.74e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
LEKDDOCD_01681	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
LEKDDOCD_01682	7.78e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEKDDOCD_01683	2.71e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
LEKDDOCD_01684	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
LEKDDOCD_01685	7.44e-15	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEKDDOCD_01686	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
LEKDDOCD_01687	1.78e-86	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
LEKDDOCD_01688	3.07e-307	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
LEKDDOCD_01689	1.6e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEKDDOCD_01690	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
LEKDDOCD_01691	1.24e-124	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
LEKDDOCD_01692	4.04e-38	-	-	-	S	-	-	-	Phage minor capsid protein 2
LEKDDOCD_01694	1.99e-08	-	-	-	S	-	-	-	Phage minor structural protein GP20
LEKDDOCD_01695	1.3e-55	-	-	-	M	-	-	-	by MetaGeneAnnotator
LEKDDOCD_01696	1.37e-140	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
LEKDDOCD_01697	7.68e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
LEKDDOCD_01698	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
LEKDDOCD_01699	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
LEKDDOCD_01700	1.48e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
LEKDDOCD_01701	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
LEKDDOCD_01702	1.9e-81	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
LEKDDOCD_01703	9.61e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEKDDOCD_01704	3.83e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
LEKDDOCD_01706	1.75e-65	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
LEKDDOCD_01707	6.95e-311	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
LEKDDOCD_01708	1.38e-59	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
LEKDDOCD_01709	7.15e-161	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEKDDOCD_01710	4.03e-54	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type i restriction
LEKDDOCD_01711	1.58e-61	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
LEKDDOCD_01713	3.97e-68	-	-	-	-	-	-	-	-
LEKDDOCD_01714	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
LEKDDOCD_01715	1.56e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEKDDOCD_01716	1.62e-174	-	-	-	P	-	-	-	Voltage gated chloride channel
LEKDDOCD_01717	9.5e-283	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
LEKDDOCD_01718	8.65e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
LEKDDOCD_01719	1.3e-180	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
LEKDDOCD_01720	4.76e-181	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEKDDOCD_01721	1.9e-52	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
LEKDDOCD_01722	3.74e-303	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
LEKDDOCD_01723	1.91e-63	-	-	-	S	-	-	-	VIT family
LEKDDOCD_01724	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
LEKDDOCD_01725	1.57e-174	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEKDDOCD_01726	4.33e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
LEKDDOCD_01727	5.32e-18	-	-	-	-	-	-	-	-
LEKDDOCD_01729	1.08e-38	-	-	-	-	-	-	-	-
LEKDDOCD_01731	2.17e-27	-	-	-	M	-	-	-	Rib/alpha-like repeat
LEKDDOCD_01732	2.46e-07	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LEKDDOCD_01733	7.83e-144	-	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
LEKDDOCD_01737	4.73e-05	-	-	-	L	-	-	-	Transposase
LEKDDOCD_01743	6.16e-12	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
LEKDDOCD_01749	2.89e-22	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
LEKDDOCD_01751	5.66e-36	-	-	-	-	-	-	-	-
LEKDDOCD_01755	1.28e-78	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
LEKDDOCD_01770	6.89e-20	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
LEKDDOCD_01773	2.74e-165	-	-	-	L	-	-	-	four-way junction helicase activity
LEKDDOCD_01778	4.34e-80	-	-	-	-	-	-	-	-
LEKDDOCD_01780	1.15e-247	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
LEKDDOCD_01782	1.66e-241	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
LEKDDOCD_01786	2.61e-309	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
LEKDDOCD_01787	1.39e-104	-	-	-	-	-	-	-	-
LEKDDOCD_01788	6.72e-10	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
LEKDDOCD_01791	5.87e-13	-	-	-	D	-	-	-	Antitoxin Phd_YefM, type II toxin-antitoxin system
LEKDDOCD_01792	8.15e-12	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
LEKDDOCD_01793	1.38e-208	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
LEKDDOCD_01797	1.21e-19	-	-	-	D	-	-	-	nuclear chromosome segregation
LEKDDOCD_01806	8.07e-120	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
LEKDDOCD_01807	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
LEKDDOCD_01808	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
LEKDDOCD_01809	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
LEKDDOCD_01810	2.18e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
LEKDDOCD_01811	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
LEKDDOCD_01812	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
LEKDDOCD_01813	9.8e-152	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
LEKDDOCD_01814	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
LEKDDOCD_01815	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
LEKDDOCD_01816	1.86e-215	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEKDDOCD_01817	8.6e-230	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
LEKDDOCD_01818	0.0	-	-	-	E	-	-	-	Amino acid permease
LEKDDOCD_01819	9.38e-110	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
LEKDDOCD_01820	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
LEKDDOCD_01821	1.92e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
LEKDDOCD_01822	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
LEKDDOCD_01823	1.15e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
LEKDDOCD_01824	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
LEKDDOCD_01827	3.98e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
LEKDDOCD_01828	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
LEKDDOCD_01829	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
LEKDDOCD_01830	5.66e-214	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEKDDOCD_01831	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEKDDOCD_01832	1.82e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEKDDOCD_01833	1.58e-156	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
LEKDDOCD_01834	8.3e-210	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEKDDOCD_01835	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEKDDOCD_01836	4.16e-272	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEKDDOCD_01837	2.01e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
LEKDDOCD_01838	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LEKDDOCD_01839	6.52e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEKDDOCD_01840	1.87e-41	-	-	-	K	-	-	-	GNAT family
LEKDDOCD_01841	1.96e-54	-	-	-	-	-	-	-	-
LEKDDOCD_01843	2.72e-237	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
LEKDDOCD_01844	1.47e-119	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEKDDOCD_01845	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEKDDOCD_01846	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
LEKDDOCD_01847	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LEKDDOCD_01848	6.02e-46	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEKDDOCD_01849	1.82e-253	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
LEKDDOCD_01850	3.92e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEKDDOCD_01851	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
LEKDDOCD_01852	5.7e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
LEKDDOCD_01853	5.04e-161	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
LEKDDOCD_01854	3.4e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
LEKDDOCD_01855	7.97e-90	mleR	-	-	K	-	-	-	LysR family
LEKDDOCD_01856	3.65e-74	napB	-	-	K	-	-	-	transcriptional
LEKDDOCD_01857	4.74e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_01858	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
LEKDDOCD_01859	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
LEKDDOCD_01860	1.19e-79	-	-	-	M	-	-	-	Rib/alpha-like repeat
LEKDDOCD_01862	2.09e-130	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
LEKDDOCD_01863	1.28e-76	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
LEKDDOCD_01864	1.54e-203	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEKDDOCD_01865	1.01e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEKDDOCD_01866	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
LEKDDOCD_01867	5.6e-249	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
LEKDDOCD_01868	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEKDDOCD_01869	1.38e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
LEKDDOCD_01870	3.69e-224	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
LEKDDOCD_01871	6e-76	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEKDDOCD_01872	1.22e-121	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEKDDOCD_01873	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
LEKDDOCD_01874	5.1e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
LEKDDOCD_01875	1.09e-65	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
LEKDDOCD_01876	2.89e-32	-	-	-	M	-	-	-	domain protein
LEKDDOCD_01877	9.33e-42	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEKDDOCD_01878	9.79e-19	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
LEKDDOCD_01879	3.98e-66	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
LEKDDOCD_01880	1.2e-203	spoVK	-	-	O	-	-	-	stage V sporulation protein K
LEKDDOCD_01881	8.5e-97	-	-	-	-	-	-	-	-
LEKDDOCD_01882	8.89e-120	-	-	-	-	-	-	-	-
LEKDDOCD_01883	1.58e-18	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the agmatine deiminase family
LEKDDOCD_01884	5.3e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
LEKDDOCD_01885	2.78e-89	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
LEKDDOCD_01886	8.34e-06	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEKDDOCD_01888	6.05e-152	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
LEKDDOCD_01889	2.72e-268	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEKDDOCD_01890	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
LEKDDOCD_01891	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEKDDOCD_01892	1.03e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEKDDOCD_01893	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEKDDOCD_01894	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
LEKDDOCD_01895	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEKDDOCD_01896	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
LEKDDOCD_01897	1.64e-182	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEKDDOCD_01900	6.89e-72	-	-	-	-	-	-	-	-
LEKDDOCD_01901	4.01e-44	-	-	-	P	-	-	-	Heavy-metal-associated domain
LEKDDOCD_01902	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
LEKDDOCD_01904	3.41e-88	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
LEKDDOCD_01905	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEKDDOCD_01906	9.98e-123	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEKDDOCD_01907	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
LEKDDOCD_01908	3.01e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
LEKDDOCD_01909	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEKDDOCD_01910	1.7e-270	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
LEKDDOCD_01911	1.21e-174	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEKDDOCD_01912	2.38e-89	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEKDDOCD_01913	8.92e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
LEKDDOCD_01914	1.45e-13	-	-	-	-	-	-	-	-
LEKDDOCD_01915	2.15e-43	-	-	-	-	-	-	-	-
LEKDDOCD_01917	1.49e-19	-	-	-	S	-	-	-	YjcQ protein
LEKDDOCD_01920	4.23e-130	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
LEKDDOCD_01921	1.85e-89	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
LEKDDOCD_01922	2.13e-100	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
LEKDDOCD_01923	3.07e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEKDDOCD_01924	1.14e-65	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
LEKDDOCD_01925	7.34e-102	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
LEKDDOCD_01926	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEKDDOCD_01927	7.1e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
LEKDDOCD_01928	2.52e-34	-	-	-	-	-	-	-	-
LEKDDOCD_01929	1.27e-70	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEKDDOCD_01933	7.06e-35	-	-	-	M	-	-	-	CHAP domain
LEKDDOCD_01935	6.39e-235	-	-	-	U	-	-	-	type IV secretory pathway VirB4
LEKDDOCD_01938	4.29e-87	-	-	-	-	-	-	-	-
LEKDDOCD_01939	1.37e-265	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
LEKDDOCD_01943	6.99e-181	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
LEKDDOCD_01946	1.35e-199	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
LEKDDOCD_01947	1.7e-25	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
LEKDDOCD_01948	5.82e-74	-	-	-	-	-	-	-	-
LEKDDOCD_01950	5.46e-06	-	-	-	-	-	-	-	-
LEKDDOCD_01951	4.25e-94	-	-	-	DM	-	-	-	Glucan-binding protein C
LEKDDOCD_01953	4.99e-136	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
LEKDDOCD_01955	1.81e-37	-	-	-	D	-	-	-	nuclear chromosome segregation
LEKDDOCD_01956	1.05e-08	-	-	-	K	-	-	-	sequence-specific DNA binding
LEKDDOCD_01957	1.14e-296	bcgIB	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
LEKDDOCD_01958	8.15e-97	-	-	-	S	-	-	-	Fic/DOC family
LEKDDOCD_01961	3.12e-39	-	-	-	L	-	-	-	four-way junction helicase activity
LEKDDOCD_01965	2.06e-11	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
LEKDDOCD_01981	1.86e-20	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Peptidase S24-like
LEKDDOCD_01984	6.76e-05	-	-	-	-	-	-	-	-
LEKDDOCD_01985	3.77e-104	-	-	-	L	-	-	-	DNA restriction-modification system
LEKDDOCD_01987	1.19e-80	-	-	-	L	-	-	-	ISXO2-like transposase domain
LEKDDOCD_01988	3.78e-110	-	-	-	S	-	-	-	Fic/DOC family