ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHCIJHAF_00001 1.22e-61 - - - L - - - Transposase
MHCIJHAF_00004 1e-144 ydeA - - S - - - DJ-1/PfpI family
MHCIJHAF_00005 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MHCIJHAF_00006 2.07e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
MHCIJHAF_00007 1.93e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHCIJHAF_00008 2.18e-213 - - - K - - - AraC-like ligand binding domain
MHCIJHAF_00009 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHCIJHAF_00010 9.98e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MHCIJHAF_00011 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_00012 1.54e-276 ydeG - - EGP - - - Major facilitator superfamily
MHCIJHAF_00013 7.55e-69 ydeH - - - - - - -
MHCIJHAF_00014 3.6e-83 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MHCIJHAF_00015 6.79e-139 - - - - - - - -
MHCIJHAF_00016 1.1e-39 - - - S - - - SNARE associated Golgi protein
MHCIJHAF_00017 1.64e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
MHCIJHAF_00018 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
MHCIJHAF_00019 4.66e-197 ydeK - - EG - - - -transporter
MHCIJHAF_00020 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_00021 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
MHCIJHAF_00022 1.43e-136 - - - S ko:K07002 - ko00000 Serine hydrolase
MHCIJHAF_00023 2.91e-72 - - - K - - - HxlR-like helix-turn-helix
MHCIJHAF_00024 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHCIJHAF_00025 5.03e-91 ydeP - - K - - - Transcriptional regulator
MHCIJHAF_00026 6.98e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
MHCIJHAF_00027 9.29e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MHCIJHAF_00028 1.46e-133 ydeS - - K - - - Transcriptional regulator
MHCIJHAF_00029 2.11e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MHCIJHAF_00030 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHCIJHAF_00031 2.59e-187 - - - J - - - GNAT acetyltransferase
MHCIJHAF_00032 1.81e-199 - - - EG - - - EamA-like transporter family
MHCIJHAF_00033 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_00034 6.97e-150 ydfE - - S - - - Flavin reductase like domain
MHCIJHAF_00035 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHCIJHAF_00036 1.6e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHCIJHAF_00038 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00039 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_00040 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MHCIJHAF_00041 6.57e-224 - - - S - - - Alpha/beta hydrolase family
MHCIJHAF_00042 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHCIJHAF_00043 1.61e-184 - - - K - - - Bacterial transcription activator, effector binding domain
MHCIJHAF_00044 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHCIJHAF_00045 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MHCIJHAF_00046 1.51e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHCIJHAF_00047 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
MHCIJHAF_00048 2.56e-72 ydfQ - - CO - - - Thioredoxin
MHCIJHAF_00049 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
MHCIJHAF_00050 5.33e-39 - - - - - - - -
MHCIJHAF_00052 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
MHCIJHAF_00053 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
MHCIJHAF_00054 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHCIJHAF_00055 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
MHCIJHAF_00056 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
MHCIJHAF_00057 5.75e-128 ydgC - - K - - - Bacterial regulatory proteins, tetR family
MHCIJHAF_00058 6.73e-69 - - - S - - - DoxX-like family
MHCIJHAF_00059 4.66e-110 yycN - - K - - - Acetyltransferase
MHCIJHAF_00060 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MHCIJHAF_00061 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_00062 1.46e-118 - - - S - - - DinB family
MHCIJHAF_00063 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_00064 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MHCIJHAF_00065 6.42e-147 ydgI - - C - - - nitroreductase
MHCIJHAF_00066 3.29e-90 - - - K - - - Winged helix DNA-binding domain
MHCIJHAF_00067 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MHCIJHAF_00068 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MHCIJHAF_00069 5.24e-158 ydhC - - K - - - FCD
MHCIJHAF_00070 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
MHCIJHAF_00071 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHCIJHAF_00072 4.79e-160 - - - - - - - -
MHCIJHAF_00073 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MHCIJHAF_00074 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MHCIJHAF_00076 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
MHCIJHAF_00077 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHCIJHAF_00078 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
MHCIJHAF_00079 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MHCIJHAF_00080 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00081 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00082 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHCIJHAF_00083 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCIJHAF_00084 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MHCIJHAF_00085 8.19e-213 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MHCIJHAF_00086 1.46e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHCIJHAF_00087 1.85e-161 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHCIJHAF_00088 1.65e-86 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHCIJHAF_00089 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
MHCIJHAF_00092 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHCIJHAF_00093 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHCIJHAF_00094 1.81e-41 yazB - - K - - - transcriptional
MHCIJHAF_00095 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHCIJHAF_00096 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHCIJHAF_00097 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHCIJHAF_00098 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MHCIJHAF_00099 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MHCIJHAF_00100 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHCIJHAF_00101 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHCIJHAF_00102 1.7e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MHCIJHAF_00103 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHCIJHAF_00104 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHCIJHAF_00105 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHCIJHAF_00106 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHCIJHAF_00107 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHCIJHAF_00108 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHCIJHAF_00109 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHCIJHAF_00110 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MHCIJHAF_00113 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MHCIJHAF_00114 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MHCIJHAF_00115 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
MHCIJHAF_00116 1.91e-66 yabP - - S - - - Sporulation protein YabP
MHCIJHAF_00117 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHCIJHAF_00118 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHCIJHAF_00119 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_00120 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MHCIJHAF_00121 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHCIJHAF_00122 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
MHCIJHAF_00123 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHCIJHAF_00124 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHCIJHAF_00125 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHCIJHAF_00126 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHCIJHAF_00127 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHCIJHAF_00128 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MHCIJHAF_00129 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHCIJHAF_00130 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHCIJHAF_00131 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
MHCIJHAF_00132 5.32e-53 veg - - S - - - protein conserved in bacteria
MHCIJHAF_00133 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
MHCIJHAF_00134 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHCIJHAF_00135 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHCIJHAF_00136 1.67e-277 yabE - - T - - - protein conserved in bacteria
MHCIJHAF_00137 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MHCIJHAF_00138 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHCIJHAF_00139 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MHCIJHAF_00140 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHCIJHAF_00141 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MHCIJHAF_00142 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MHCIJHAF_00143 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
MHCIJHAF_00144 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MHCIJHAF_00145 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHCIJHAF_00146 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MHCIJHAF_00147 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
MHCIJHAF_00148 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHCIJHAF_00149 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MHCIJHAF_00150 6.87e-258 yaaN - - P - - - Belongs to the TelA family
MHCIJHAF_00151 2.7e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHCIJHAF_00152 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
MHCIJHAF_00153 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MHCIJHAF_00154 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHCIJHAF_00155 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHCIJHAF_00156 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
MHCIJHAF_00157 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHCIJHAF_00158 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MHCIJHAF_00159 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHCIJHAF_00160 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHCIJHAF_00161 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHCIJHAF_00162 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHCIJHAF_00163 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MHCIJHAF_00164 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHCIJHAF_00165 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHCIJHAF_00166 2.9e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHCIJHAF_00167 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHCIJHAF_00168 2.18e-96 - - - S - - - Bacterial PH domain
MHCIJHAF_00169 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MHCIJHAF_00170 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHCIJHAF_00171 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
MHCIJHAF_00172 5.34e-227 yyaD - - S - - - Membrane
MHCIJHAF_00173 7.41e-45 yyzM - - S - - - protein conserved in bacteria
MHCIJHAF_00174 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHCIJHAF_00175 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHCIJHAF_00176 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHCIJHAF_00177 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHCIJHAF_00178 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHCIJHAF_00179 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHCIJHAF_00180 6.85e-227 ccpB - - K - - - Transcriptional regulator
MHCIJHAF_00181 2.32e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_00182 3.81e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
MHCIJHAF_00183 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
MHCIJHAF_00184 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCIJHAF_00185 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MHCIJHAF_00186 1.34e-205 - - - EG - - - EamA-like transporter family
MHCIJHAF_00187 1.34e-88 - - - K - - - MerR HTH family regulatory protein
MHCIJHAF_00188 2.16e-07 - - - S - - - Putative amidase domain
MHCIJHAF_00190 9.19e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MHCIJHAF_00191 8.09e-314 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_00192 8.62e-137 yyaP - - H - - - RibD C-terminal domain
MHCIJHAF_00193 1.5e-85 - - - S - - - YjbR
MHCIJHAF_00194 2.72e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MHCIJHAF_00195 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
MHCIJHAF_00196 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHCIJHAF_00197 4.54e-100 yybA - - K - - - transcriptional
MHCIJHAF_00198 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
MHCIJHAF_00199 5.79e-96 yybC - - - - - - -
MHCIJHAF_00200 4.58e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHCIJHAF_00201 4.56e-211 yybE - - K - - - Transcriptional regulator
MHCIJHAF_00202 2.04e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_00203 1.98e-162 yybG - - S - - - Pentapeptide repeat-containing protein
MHCIJHAF_00204 1.38e-84 - - - S - - - SnoaL-like domain
MHCIJHAF_00205 7.14e-184 - - - - - - - -
MHCIJHAF_00206 3.59e-141 - - - K - - - TipAS antibiotic-recognition domain
MHCIJHAF_00207 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_00209 3.73e-89 - - - - - - - -
MHCIJHAF_00210 6.65e-208 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MHCIJHAF_00211 1.3e-87 yybR - - K - - - Transcriptional regulator
MHCIJHAF_00212 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
MHCIJHAF_00214 1.5e-204 yybS - - S - - - membrane
MHCIJHAF_00215 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHCIJHAF_00216 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MHCIJHAF_00217 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHCIJHAF_00218 1.2e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MHCIJHAF_00219 1.89e-22 yycC - - K - - - YycC-like protein
MHCIJHAF_00221 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MHCIJHAF_00222 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHCIJHAF_00223 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_00224 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHCIJHAF_00229 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_00230 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00231 0.0 yycH - - S - - - protein conserved in bacteria
MHCIJHAF_00232 2.83e-199 yycI - - S - - - protein conserved in bacteria
MHCIJHAF_00233 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHCIJHAF_00234 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHCIJHAF_00235 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
MHCIJHAF_00236 2.66e-97 - - - S - - - Peptidase propeptide and YPEB domain
MHCIJHAF_00237 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
MHCIJHAF_00238 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHCIJHAF_00239 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHCIJHAF_00240 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHCIJHAF_00241 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHCIJHAF_00242 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MHCIJHAF_00244 1.06e-239 - - - S - - - aspartate phosphatase
MHCIJHAF_00245 9.06e-112 yycN - - K - - - Acetyltransferase
MHCIJHAF_00246 2.78e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHCIJHAF_00247 7.25e-265 yycP - - - - - - -
MHCIJHAF_00248 4.71e-43 yycQ - - S - - - Protein of unknown function (DUF2651)
MHCIJHAF_00250 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHCIJHAF_00251 2.62e-86 - - - - - - - -
MHCIJHAF_00253 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHCIJHAF_00255 8.29e-31 - - - I - - - PLD-like domain
MHCIJHAF_00256 3.27e-60 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MHCIJHAF_00258 5.84e-223 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MHCIJHAF_00259 1.67e-64 - - - L - - - EcoRII C terminal
MHCIJHAF_00260 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MHCIJHAF_00261 1.44e-24 - - - - - - - -
MHCIJHAF_00262 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_00263 9.47e-24 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00264 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCIJHAF_00265 1.11e-237 - - - S - - - Polysaccharide pyruvyl transferase
MHCIJHAF_00266 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MHCIJHAF_00267 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MHCIJHAF_00268 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHCIJHAF_00269 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MHCIJHAF_00270 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MHCIJHAF_00271 3.63e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
MHCIJHAF_00272 8.14e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MHCIJHAF_00273 1.21e-243 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MHCIJHAF_00274 2.19e-153 yxaC - - M - - - effector of murein hydrolase
MHCIJHAF_00275 6.51e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MHCIJHAF_00276 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_00277 6.1e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_00278 2.75e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MHCIJHAF_00279 3e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
MHCIJHAF_00280 4.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MHCIJHAF_00281 4.03e-99 yxaI - - S - - - membrane protein domain
MHCIJHAF_00282 1.38e-83 - - - S - - - Family of unknown function (DUF5391)
MHCIJHAF_00283 1.4e-134 yxaL - - S - - - PQQ-like domain
MHCIJHAF_00284 9.97e-43 yxaI - - S - - - membrane protein domain
MHCIJHAF_00285 1.14e-311 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHCIJHAF_00286 3.09e-267 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MHCIJHAF_00287 4.85e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_00289 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MHCIJHAF_00290 5.91e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCIJHAF_00291 2.39e-61 yxcD - - S - - - Protein of unknown function (DUF2653)
MHCIJHAF_00293 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MHCIJHAF_00294 2.58e-176 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHCIJHAF_00295 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHCIJHAF_00296 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHCIJHAF_00297 1.43e-226 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHCIJHAF_00298 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHCIJHAF_00299 2.47e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHCIJHAF_00300 1.63e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MHCIJHAF_00301 1.27e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHCIJHAF_00302 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MHCIJHAF_00303 2.67e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHCIJHAF_00304 5.48e-202 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHCIJHAF_00305 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_00306 7.73e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00307 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_00308 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MHCIJHAF_00309 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
MHCIJHAF_00310 4.28e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCIJHAF_00311 9.65e-91 - - - - - - - -
MHCIJHAF_00312 1.78e-09 yxeD - - - - - - -
MHCIJHAF_00313 7.32e-42 yxeE - - - - - - -
MHCIJHAF_00316 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
MHCIJHAF_00317 1.84e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHCIJHAF_00318 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_00319 3.63e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_00320 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHCIJHAF_00321 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHCIJHAF_00322 4.8e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_00323 1.67e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MHCIJHAF_00324 8.39e-314 yxeQ - - S - - - MmgE/PrpD family
MHCIJHAF_00325 1.01e-251 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
MHCIJHAF_00326 1.36e-185 - - - S - - - Domain of Unknown Function (DUF1206)
MHCIJHAF_00327 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHCIJHAF_00328 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHCIJHAF_00329 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHCIJHAF_00330 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MHCIJHAF_00331 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHCIJHAF_00332 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHCIJHAF_00333 8.72e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MHCIJHAF_00334 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHCIJHAF_00335 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MHCIJHAF_00336 3.34e-101 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHCIJHAF_00337 5.13e-16 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MHCIJHAF_00339 4.54e-13 - - - S - - - Oxidoreductase
MHCIJHAF_00340 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MHCIJHAF_00341 5.09e-35 - - - S - - - Domain of unknown function (DUF5082)
MHCIJHAF_00342 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
MHCIJHAF_00343 0.0 - - - S - - - nuclease activity
MHCIJHAF_00344 1.08e-63 - - - - - - - -
MHCIJHAF_00345 8.25e-69 - - - - - - - -
MHCIJHAF_00346 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00347 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCIJHAF_00348 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
MHCIJHAF_00349 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
MHCIJHAF_00350 1.21e-163 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_00351 5.7e-210 yxxF - - EG - - - EamA-like transporter family
MHCIJHAF_00352 3.23e-108 yxiI - - S - - - Protein of unknown function (DUF2716)
MHCIJHAF_00353 3.48e-59 yxiJ - - S - - - YxiJ-like protein
MHCIJHAF_00356 6.89e-81 - - - S - - - Protein of unknown function (DUF2812)
MHCIJHAF_00357 1.31e-70 - - - K - - - Transcriptional regulator PadR-like family
MHCIJHAF_00358 4.4e-268 - - - E - - - GDSL-like Lipase/Acylhydrolase
MHCIJHAF_00359 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MHCIJHAF_00360 1.55e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MHCIJHAF_00361 5.09e-141 - - - - - - - -
MHCIJHAF_00362 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHCIJHAF_00363 7.21e-183 bglS - - M - - - licheninase activity
MHCIJHAF_00364 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MHCIJHAF_00365 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHCIJHAF_00366 2.28e-63 yxiS - - - - - - -
MHCIJHAF_00367 4.89e-132 - - - T - - - Domain of unknown function (DUF4163)
MHCIJHAF_00368 8.54e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHCIJHAF_00369 3.44e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MHCIJHAF_00370 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
MHCIJHAF_00371 1.82e-165 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHCIJHAF_00372 2.41e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHCIJHAF_00373 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHCIJHAF_00374 1.55e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MHCIJHAF_00375 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MHCIJHAF_00376 1.43e-111 yxjI - - S - - - LURP-one-related
MHCIJHAF_00379 4.49e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHCIJHAF_00380 7.4e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
MHCIJHAF_00381 1.37e-258 - - - T - - - Signal transduction histidine kinase
MHCIJHAF_00382 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
MHCIJHAF_00383 3.62e-212 - - - K - - - LysR substrate binding domain
MHCIJHAF_00384 7.88e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MHCIJHAF_00385 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHCIJHAF_00386 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
MHCIJHAF_00387 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHCIJHAF_00388 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHCIJHAF_00389 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MHCIJHAF_00390 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_00391 7.49e-199 yxkH - - G - - - Polysaccharide deacetylase
MHCIJHAF_00393 0.0 - - - O - - - Peptidase family M48
MHCIJHAF_00394 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
MHCIJHAF_00395 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MHCIJHAF_00396 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MHCIJHAF_00397 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MHCIJHAF_00398 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MHCIJHAF_00399 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHCIJHAF_00400 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MHCIJHAF_00401 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_00402 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
MHCIJHAF_00403 2.92e-42 - - - - - - - -
MHCIJHAF_00404 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
MHCIJHAF_00405 5.52e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_00406 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHCIJHAF_00407 2.48e-274 yxlH - - EGP - - - Major Facilitator Superfamily
MHCIJHAF_00408 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHCIJHAF_00409 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MHCIJHAF_00410 8.94e-28 yxzF - - - - - - -
MHCIJHAF_00411 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHCIJHAF_00412 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MHCIJHAF_00413 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHCIJHAF_00414 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00415 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHCIJHAF_00416 2.52e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHCIJHAF_00417 6.86e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_00418 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHCIJHAF_00419 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_00420 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MHCIJHAF_00421 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_00422 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MHCIJHAF_00423 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MHCIJHAF_00424 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
MHCIJHAF_00425 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MHCIJHAF_00426 5.37e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_00427 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MHCIJHAF_00428 4.11e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHCIJHAF_00429 1.25e-114 ywaE - - K - - - Transcriptional regulator
MHCIJHAF_00430 9.6e-156 ywaF - - S - - - Integral membrane protein
MHCIJHAF_00431 4.41e-215 gspA - - M - - - General stress
MHCIJHAF_00432 1.06e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHCIJHAF_00433 6.87e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00434 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCIJHAF_00435 5.24e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHCIJHAF_00436 3.3e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MHCIJHAF_00437 3.29e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MHCIJHAF_00438 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MHCIJHAF_00439 4.13e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
MHCIJHAF_00440 1.21e-143 ywbG - - M - - - effector of murein hydrolase
MHCIJHAF_00441 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHCIJHAF_00442 1.56e-202 ywbI - - K - - - Transcriptional regulator
MHCIJHAF_00443 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHCIJHAF_00444 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHCIJHAF_00445 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MHCIJHAF_00446 6.92e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MHCIJHAF_00447 1.04e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MHCIJHAF_00448 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MHCIJHAF_00449 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCIJHAF_00450 4.29e-64 ywcB - - S - - - Protein of unknown function, DUF485
MHCIJHAF_00452 3.42e-158 ywcC - - K - - - transcriptional regulator
MHCIJHAF_00453 3.33e-77 gtcA - - S - - - GtrA-like protein
MHCIJHAF_00454 1.12e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHCIJHAF_00455 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHCIJHAF_00456 5.11e-49 ydaS - - S - - - membrane
MHCIJHAF_00457 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHCIJHAF_00458 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHCIJHAF_00459 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MHCIJHAF_00460 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MHCIJHAF_00461 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MHCIJHAF_00462 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHCIJHAF_00463 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MHCIJHAF_00464 1.99e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_00465 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCIJHAF_00467 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHCIJHAF_00468 2.79e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
MHCIJHAF_00469 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_00470 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHCIJHAF_00471 6.19e-39 ywdA - - - - - - -
MHCIJHAF_00472 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHCIJHAF_00473 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHCIJHAF_00474 2.4e-143 ywdD - - - - - - -
MHCIJHAF_00476 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
MHCIJHAF_00477 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHCIJHAF_00478 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHCIJHAF_00479 2.65e-64 ywdI - - S - - - Family of unknown function (DUF5327)
MHCIJHAF_00480 3.75e-303 ywdJ - - F - - - Xanthine uracil
MHCIJHAF_00481 1.59e-78 ywdK - - S - - - small membrane protein
MHCIJHAF_00482 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHCIJHAF_00483 7.76e-185 spsA - - M - - - Spore Coat
MHCIJHAF_00484 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MHCIJHAF_00485 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MHCIJHAF_00486 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MHCIJHAF_00487 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MHCIJHAF_00488 1.09e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
MHCIJHAF_00489 5.73e-240 spsG - - M - - - Spore Coat
MHCIJHAF_00490 2.14e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHCIJHAF_00491 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHCIJHAF_00492 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHCIJHAF_00493 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MHCIJHAF_00494 1.51e-100 - - - - - - - -
MHCIJHAF_00495 8.6e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHCIJHAF_00496 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHCIJHAF_00497 0.0 rocB - - E - - - arginine degradation protein
MHCIJHAF_00498 1.09e-42 rocB - - E - - - arginine degradation protein
MHCIJHAF_00499 1.77e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHCIJHAF_00500 5.41e-275 ywfA - - EGP - - - -transporter
MHCIJHAF_00501 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MHCIJHAF_00502 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MHCIJHAF_00503 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_00504 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MHCIJHAF_00505 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MHCIJHAF_00506 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MHCIJHAF_00507 2.77e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_00508 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MHCIJHAF_00509 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MHCIJHAF_00510 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_00511 3.05e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHCIJHAF_00512 2.14e-202 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
MHCIJHAF_00513 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MHCIJHAF_00514 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MHCIJHAF_00515 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MHCIJHAF_00516 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
MHCIJHAF_00517 3.15e-103 yffB - - K - - - Transcriptional regulator
MHCIJHAF_00518 1.59e-302 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MHCIJHAF_00520 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHCIJHAF_00521 1.76e-94 ywhA - - K - - - Transcriptional regulator
MHCIJHAF_00522 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MHCIJHAF_00523 3.29e-154 ywhC - - S - - - Peptidase family M50
MHCIJHAF_00524 2.24e-122 ywhD - - S - - - YwhD family
MHCIJHAF_00525 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHCIJHAF_00526 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHCIJHAF_00527 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MHCIJHAF_00529 1.32e-106 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MHCIJHAF_00530 1.12e-289 ywhK - - CO - - - amine dehydrogenase activity
MHCIJHAF_00531 9.08e-317 ywhL - - CO - - - amine dehydrogenase activity
MHCIJHAF_00533 3.32e-315 - - - L - - - Peptidase, M16
MHCIJHAF_00534 4.88e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
MHCIJHAF_00535 8.05e-296 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
MHCIJHAF_00536 1.23e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHCIJHAF_00538 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
MHCIJHAF_00539 3.71e-12 - - - S - - - Bacteriocin subtilosin A
MHCIJHAF_00540 4.64e-96 ywiB - - S - - - protein conserved in bacteria
MHCIJHAF_00541 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHCIJHAF_00542 1.7e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MHCIJHAF_00543 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MHCIJHAF_00544 1.84e-179 ywiC - - S - - - YwiC-like protein
MHCIJHAF_00545 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MHCIJHAF_00546 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHCIJHAF_00547 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MHCIJHAF_00548 5.59e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MHCIJHAF_00549 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MHCIJHAF_00550 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHCIJHAF_00551 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHCIJHAF_00552 1.57e-123 ywjB - - H - - - RibD C-terminal domain
MHCIJHAF_00553 1.32e-57 ywjC - - - - - - -
MHCIJHAF_00554 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHCIJHAF_00555 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHCIJHAF_00556 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MHCIJHAF_00557 4.95e-268 acdA - - I - - - acyl-CoA dehydrogenase
MHCIJHAF_00558 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHCIJHAF_00559 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHCIJHAF_00560 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
MHCIJHAF_00561 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MHCIJHAF_00562 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MHCIJHAF_00563 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHCIJHAF_00564 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHCIJHAF_00565 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MHCIJHAF_00566 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHCIJHAF_00567 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MHCIJHAF_00568 4.06e-134 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHCIJHAF_00569 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MHCIJHAF_00570 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MHCIJHAF_00571 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MHCIJHAF_00572 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_00573 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHCIJHAF_00574 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHCIJHAF_00576 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHCIJHAF_00577 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MHCIJHAF_00578 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MHCIJHAF_00579 8.6e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHCIJHAF_00580 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
MHCIJHAF_00581 7.84e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHCIJHAF_00582 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MHCIJHAF_00583 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
MHCIJHAF_00584 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHCIJHAF_00585 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHCIJHAF_00586 2.23e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MHCIJHAF_00587 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHCIJHAF_00588 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHCIJHAF_00589 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHCIJHAF_00590 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHCIJHAF_00591 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHCIJHAF_00592 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHCIJHAF_00593 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHCIJHAF_00594 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHCIJHAF_00595 6.12e-115 ywmA - - - - - - -
MHCIJHAF_00596 4.54e-45 ywzB - - S - - - membrane
MHCIJHAF_00597 6.32e-170 ywmB - - S - - - TATA-box binding
MHCIJHAF_00598 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHCIJHAF_00599 3.27e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MHCIJHAF_00600 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHCIJHAF_00601 4.14e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHCIJHAF_00603 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHCIJHAF_00604 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHCIJHAF_00605 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHCIJHAF_00606 1.12e-109 ywmF - - S - - - Peptidase M50
MHCIJHAF_00607 1.51e-19 csbD - - K - - - CsbD-like
MHCIJHAF_00608 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MHCIJHAF_00609 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MHCIJHAF_00610 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHCIJHAF_00611 4.58e-85 ywnA - - K - - - Transcriptional regulator
MHCIJHAF_00612 1.02e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MHCIJHAF_00613 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
MHCIJHAF_00614 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MHCIJHAF_00615 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHCIJHAF_00616 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
MHCIJHAF_00617 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
MHCIJHAF_00618 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MHCIJHAF_00619 1.3e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MHCIJHAF_00620 1.65e-40 - - - L - - - Restriction endonuclease BamHI
MHCIJHAF_00621 2.47e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_00622 2.35e-152 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MHCIJHAF_00623 2.35e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MHCIJHAF_00624 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MHCIJHAF_00625 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MHCIJHAF_00626 7.16e-101 - - - - - - - -
MHCIJHAF_00627 3e-133 yjgF - - Q - - - Isochorismatase family
MHCIJHAF_00628 3.63e-305 ywoD - - EGP - - - Major facilitator superfamily
MHCIJHAF_00629 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MHCIJHAF_00630 1.45e-312 ywoF - - P - - - Right handed beta helix region
MHCIJHAF_00631 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_00632 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
MHCIJHAF_00633 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MHCIJHAF_00634 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MHCIJHAF_00635 1.19e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MHCIJHAF_00636 9.65e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MHCIJHAF_00637 6.36e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MHCIJHAF_00638 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHCIJHAF_00639 1.32e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHCIJHAF_00640 4.34e-189 ywpD - - T - - - Histidine kinase
MHCIJHAF_00641 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHCIJHAF_00642 8.81e-89 ywpF - - S - - - YwpF-like protein
MHCIJHAF_00643 3.04e-87 ywpG - - - - - - -
MHCIJHAF_00644 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MHCIJHAF_00645 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHCIJHAF_00646 4.34e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MHCIJHAF_00647 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHCIJHAF_00648 0.0 ywqB - - S - - - SWIM zinc finger
MHCIJHAF_00649 3.6e-25 - - - - - - - -
MHCIJHAF_00650 3.6e-161 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MHCIJHAF_00651 1.76e-153 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MHCIJHAF_00652 5.87e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MHCIJHAF_00653 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHCIJHAF_00654 1.2e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
MHCIJHAF_00656 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
MHCIJHAF_00657 1.95e-297 ywqJ - - S - - - Pre-toxin TG
MHCIJHAF_00658 1.29e-97 - - - - - - - -
MHCIJHAF_00659 2.2e-66 - - - - - - - -
MHCIJHAF_00661 1.13e-126 - - - - - - - -
MHCIJHAF_00662 4.92e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MHCIJHAF_00663 4.73e-209 - - - K - - - Transcriptional regulator
MHCIJHAF_00664 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
MHCIJHAF_00666 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MHCIJHAF_00667 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MHCIJHAF_00668 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MHCIJHAF_00669 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MHCIJHAF_00670 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
MHCIJHAF_00671 8.79e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MHCIJHAF_00672 2.17e-16 - - - - - - - -
MHCIJHAF_00673 4.57e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
MHCIJHAF_00674 1.35e-180 cotB - - - ko:K06325 - ko00000 -
MHCIJHAF_00675 9.09e-164 ywrJ - - - - - - -
MHCIJHAF_00676 3.25e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHCIJHAF_00677 3.36e-218 alsR - - K - - - LysR substrate binding domain
MHCIJHAF_00678 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHCIJHAF_00679 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHCIJHAF_00680 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MHCIJHAF_00681 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
MHCIJHAF_00682 2.05e-121 batE - - T - - - Sh3 type 3 domain protein
MHCIJHAF_00683 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MHCIJHAF_00684 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHCIJHAF_00685 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHCIJHAF_00686 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHCIJHAF_00687 3.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHCIJHAF_00688 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
MHCIJHAF_00689 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MHCIJHAF_00690 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MHCIJHAF_00691 1.56e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MHCIJHAF_00692 4.62e-29 ywtC - - - - - - -
MHCIJHAF_00693 3.22e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHCIJHAF_00694 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MHCIJHAF_00695 1.22e-221 ywtF_2 - - K - - - Transcriptional regulator
MHCIJHAF_00696 6.46e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCIJHAF_00697 3.25e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MHCIJHAF_00698 2.5e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MHCIJHAF_00699 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MHCIJHAF_00700 2.73e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHCIJHAF_00701 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHCIJHAF_00702 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHCIJHAF_00703 1.34e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHCIJHAF_00704 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MHCIJHAF_00705 1.7e-133 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MHCIJHAF_00706 8.85e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHCIJHAF_00707 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHCIJHAF_00708 1.88e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MHCIJHAF_00709 1.2e-170 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHCIJHAF_00710 1.26e-304 - - - M - - - Glycosyltransferase like family 2
MHCIJHAF_00711 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHCIJHAF_00712 4.79e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MHCIJHAF_00713 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHCIJHAF_00714 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHCIJHAF_00716 1.37e-117 - - - M - - - Glycosyl transferases group 1
MHCIJHAF_00717 1.06e-103 - - - M - - - Glycosyltransferase like family 2
MHCIJHAF_00718 1.56e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHCIJHAF_00719 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHCIJHAF_00720 4.58e-16 - - - - - - - -
MHCIJHAF_00721 0.0 lytB - - D - - - Stage II sporulation protein
MHCIJHAF_00722 2.25e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHCIJHAF_00723 7e-108 - - - M - - - Glycosyltransferase like family 2
MHCIJHAF_00724 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHCIJHAF_00725 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_00726 3.83e-277 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MHCIJHAF_00727 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHCIJHAF_00728 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MHCIJHAF_00729 1.36e-145 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MHCIJHAF_00730 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MHCIJHAF_00731 2.49e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MHCIJHAF_00732 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHCIJHAF_00733 8.05e-225 yvhJ - - K - - - Transcriptional regulator
MHCIJHAF_00734 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MHCIJHAF_00735 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHCIJHAF_00736 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_00737 2.15e-199 degV - - S - - - protein conserved in bacteria
MHCIJHAF_00738 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHCIJHAF_00739 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MHCIJHAF_00740 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MHCIJHAF_00741 1.83e-96 yvyF - - S - - - flagellar protein
MHCIJHAF_00742 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MHCIJHAF_00743 3.5e-102 yvyG - - NOU - - - FlgN protein
MHCIJHAF_00744 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MHCIJHAF_00745 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MHCIJHAF_00746 4.19e-93 yviE - - - - - - -
MHCIJHAF_00747 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHCIJHAF_00748 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHCIJHAF_00749 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHCIJHAF_00750 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
MHCIJHAF_00751 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHCIJHAF_00752 2.45e-89 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MHCIJHAF_00753 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MHCIJHAF_00754 9.14e-88 - - - - - - - -
MHCIJHAF_00755 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHCIJHAF_00756 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHCIJHAF_00757 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHCIJHAF_00758 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHCIJHAF_00759 5.16e-72 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MHCIJHAF_00760 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MHCIJHAF_00761 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHCIJHAF_00762 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHCIJHAF_00763 1.38e-73 swrA - - S - - - Swarming motility protein
MHCIJHAF_00764 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHCIJHAF_00765 5.01e-294 yvkA - - P - - - -transporter
MHCIJHAF_00766 9.63e-130 yvkB - - K - - - Transcriptional regulator
MHCIJHAF_00767 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MHCIJHAF_00768 2.54e-42 csbA - - S - - - protein conserved in bacteria
MHCIJHAF_00769 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHCIJHAF_00770 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHCIJHAF_00771 4.77e-100 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHCIJHAF_00772 2.25e-45 yvkN - - - - - - -
MHCIJHAF_00773 8.09e-65 yvlA - - - - - - -
MHCIJHAF_00774 5.8e-221 yvlB - - S - - - Putative adhesin
MHCIJHAF_00775 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MHCIJHAF_00776 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
MHCIJHAF_00777 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
MHCIJHAF_00778 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_00779 1.23e-174 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MHCIJHAF_00780 1.88e-292 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHCIJHAF_00781 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_00782 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MHCIJHAF_00783 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MHCIJHAF_00784 8.99e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHCIJHAF_00785 2.41e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHCIJHAF_00786 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHCIJHAF_00787 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHCIJHAF_00788 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
MHCIJHAF_00789 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHCIJHAF_00790 3.58e-119 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MHCIJHAF_00791 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
MHCIJHAF_00792 1.76e-178 yvpB - - NU - - - protein conserved in bacteria
MHCIJHAF_00793 1.9e-278 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHCIJHAF_00794 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHCIJHAF_00795 1.05e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHCIJHAF_00796 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MHCIJHAF_00797 2.82e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHCIJHAF_00798 2.28e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHCIJHAF_00799 2.79e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHCIJHAF_00800 2.51e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MHCIJHAF_00801 8.75e-91 - - - - - - - -
MHCIJHAF_00802 6.58e-95 - - - - - - - -
MHCIJHAF_00803 0.0 - - - - - - - -
MHCIJHAF_00805 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHCIJHAF_00806 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MHCIJHAF_00807 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MHCIJHAF_00808 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHCIJHAF_00809 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHCIJHAF_00810 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHCIJHAF_00811 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHCIJHAF_00812 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHCIJHAF_00813 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MHCIJHAF_00814 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MHCIJHAF_00815 1.32e-43 - - - - - - - -
MHCIJHAF_00816 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_00817 2.78e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
MHCIJHAF_00818 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_00819 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MHCIJHAF_00820 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCIJHAF_00821 4.36e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MHCIJHAF_00822 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MHCIJHAF_00823 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MHCIJHAF_00824 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MHCIJHAF_00825 1.27e-220 yvdE - - K - - - Transcriptional regulator
MHCIJHAF_00826 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
MHCIJHAF_00827 2.42e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MHCIJHAF_00828 5e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MHCIJHAF_00829 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MHCIJHAF_00830 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
MHCIJHAF_00831 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
MHCIJHAF_00832 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHCIJHAF_00833 6.78e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHCIJHAF_00834 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHCIJHAF_00836 2.71e-233 - - - S - - - Patatin-like phospholipase
MHCIJHAF_00837 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MHCIJHAF_00838 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
MHCIJHAF_00839 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MHCIJHAF_00840 3.65e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MHCIJHAF_00841 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
MHCIJHAF_00842 0.0 ybeC - - E - - - amino acid
MHCIJHAF_00843 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MHCIJHAF_00844 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MHCIJHAF_00845 0.0 pbpE - - V - - - Beta-lactamase
MHCIJHAF_00846 8.37e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHCIJHAF_00847 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
MHCIJHAF_00848 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MHCIJHAF_00850 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MHCIJHAF_00851 1.45e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MHCIJHAF_00852 5.6e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MHCIJHAF_00853 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MHCIJHAF_00854 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MHCIJHAF_00855 6.66e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MHCIJHAF_00856 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHCIJHAF_00857 5.9e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHCIJHAF_00858 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MHCIJHAF_00859 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MHCIJHAF_00860 3.16e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MHCIJHAF_00861 1.86e-243 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHCIJHAF_00862 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_00863 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHCIJHAF_00864 1.15e-80 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MHCIJHAF_00865 5.25e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MHCIJHAF_00866 1.03e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MHCIJHAF_00867 5.69e-44 yvfG - - S - - - YvfG protein
MHCIJHAF_00868 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHCIJHAF_00869 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MHCIJHAF_00870 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MHCIJHAF_00871 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_00872 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MHCIJHAF_00873 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MHCIJHAF_00874 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MHCIJHAF_00875 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
MHCIJHAF_00876 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MHCIJHAF_00877 2.68e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
MHCIJHAF_00878 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
MHCIJHAF_00879 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MHCIJHAF_00880 4.81e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MHCIJHAF_00881 2.98e-249 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00882 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_00883 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHCIJHAF_00884 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHCIJHAF_00885 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHCIJHAF_00886 4.44e-251 - - - S - - - Glycosyl hydrolase
MHCIJHAF_00887 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_00888 3.93e-198 yvbV - - EG - - - EamA-like transporter family
MHCIJHAF_00889 6.96e-206 yvbU - - K - - - Transcriptional regulator
MHCIJHAF_00890 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_00891 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MHCIJHAF_00892 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCIJHAF_00893 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHCIJHAF_00894 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHCIJHAF_00895 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHCIJHAF_00896 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHCIJHAF_00897 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MHCIJHAF_00898 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHCIJHAF_00899 9.77e-106 yvbK - - K - - - acetyltransferase
MHCIJHAF_00900 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHCIJHAF_00901 7.97e-157 yvbI - - M - - - Membrane
MHCIJHAF_00902 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
MHCIJHAF_00903 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MHCIJHAF_00904 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MHCIJHAF_00905 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHCIJHAF_00906 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHCIJHAF_00907 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHCIJHAF_00908 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHCIJHAF_00909 9.63e-60 sdpR - - K - - - transcriptional
MHCIJHAF_00910 1.13e-130 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MHCIJHAF_00912 1.13e-222 - - - - - - - -
MHCIJHAF_00913 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
MHCIJHAF_00914 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MHCIJHAF_00915 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHCIJHAF_00916 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHCIJHAF_00917 6.8e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHCIJHAF_00918 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHCIJHAF_00919 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_00920 3.85e-72 yvaP - - K - - - transcriptional
MHCIJHAF_00921 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHCIJHAF_00922 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MHCIJHAF_00923 3.44e-48 yvzC - - K - - - transcriptional
MHCIJHAF_00924 1.92e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
MHCIJHAF_00925 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MHCIJHAF_00926 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MHCIJHAF_00927 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHCIJHAF_00928 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHCIJHAF_00930 6.56e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_00931 1.93e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MHCIJHAF_00932 1.44e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MHCIJHAF_00933 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MHCIJHAF_00934 0.0 - - - S - - - Fusaric acid resistance protein-like
MHCIJHAF_00935 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHCIJHAF_00936 8.46e-249 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MHCIJHAF_00937 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MHCIJHAF_00938 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
MHCIJHAF_00939 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHCIJHAF_00940 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MHCIJHAF_00941 3.45e-137 bdbD - - O - - - Thioredoxin
MHCIJHAF_00942 2.83e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MHCIJHAF_00943 3.88e-140 yvgT - - S - - - membrane
MHCIJHAF_00944 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHCIJHAF_00945 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHCIJHAF_00946 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHCIJHAF_00947 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MHCIJHAF_00948 7.97e-113 yvgO - - - - - - -
MHCIJHAF_00949 6.19e-201 yvgN - - S - - - reductase
MHCIJHAF_00950 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MHCIJHAF_00951 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MHCIJHAF_00952 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MHCIJHAF_00953 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MHCIJHAF_00954 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MHCIJHAF_00955 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MHCIJHAF_00956 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MHCIJHAF_00958 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCIJHAF_00959 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_00960 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_00961 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHCIJHAF_00962 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
MHCIJHAF_00963 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_00964 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MHCIJHAF_00965 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
MHCIJHAF_00966 4.39e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MHCIJHAF_00967 3.46e-26 - - - S - - - YvrJ protein family
MHCIJHAF_00968 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MHCIJHAF_00969 5.07e-32 - - - - - - - -
MHCIJHAF_00970 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_00971 0.0 yvrG - - T - - - Histidine kinase
MHCIJHAF_00972 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MHCIJHAF_00973 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_00974 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHCIJHAF_00975 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_00976 5.92e-315 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MHCIJHAF_00977 3.34e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MHCIJHAF_00978 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_00979 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MHCIJHAF_00980 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MHCIJHAF_00981 3.11e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MHCIJHAF_00982 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MHCIJHAF_00983 9.56e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00984 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_00985 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MHCIJHAF_00986 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MHCIJHAF_00987 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MHCIJHAF_00988 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
MHCIJHAF_00989 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHCIJHAF_00990 3.06e-204 yuxN - - K - - - Transcriptional regulator
MHCIJHAF_00991 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_00992 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_00993 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHCIJHAF_00994 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
MHCIJHAF_00995 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_00996 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MHCIJHAF_00997 3.48e-88 - - - S - - - YusW-like protein
MHCIJHAF_00998 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHCIJHAF_00999 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
MHCIJHAF_01000 4.87e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MHCIJHAF_01001 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_01002 1.7e-84 yusQ - - S - - - Tautomerase enzyme
MHCIJHAF_01003 0.0 yusP - - P - - - Major facilitator superfamily
MHCIJHAF_01004 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MHCIJHAF_01005 8.66e-70 yusN - - M - - - Coat F domain
MHCIJHAF_01006 2.23e-54 - - - - - - - -
MHCIJHAF_01007 3.46e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MHCIJHAF_01008 1.11e-13 - - - S - - - YuzL-like protein
MHCIJHAF_01009 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MHCIJHAF_01010 2.22e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MHCIJHAF_01011 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MHCIJHAF_01012 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MHCIJHAF_01013 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHCIJHAF_01014 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
MHCIJHAF_01015 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MHCIJHAF_01016 2e-73 yusE - - CO - - - Thioredoxin
MHCIJHAF_01017 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
MHCIJHAF_01018 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHCIJHAF_01019 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MHCIJHAF_01020 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MHCIJHAF_01021 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHCIJHAF_01022 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHCIJHAF_01023 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MHCIJHAF_01024 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHCIJHAF_01025 2.55e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MHCIJHAF_01026 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MHCIJHAF_01027 7.18e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_01028 1.12e-54 - - - - - - - -
MHCIJHAF_01030 6.46e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MHCIJHAF_01031 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MHCIJHAF_01032 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MHCIJHAF_01033 5.79e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MHCIJHAF_01034 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_01035 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MHCIJHAF_01036 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MHCIJHAF_01037 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MHCIJHAF_01038 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_01039 6.53e-218 bsn - - L - - - Ribonuclease
MHCIJHAF_01040 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHCIJHAF_01041 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHCIJHAF_01043 3.87e-238 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MHCIJHAF_01044 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MHCIJHAF_01045 6.5e-183 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MHCIJHAF_01046 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MHCIJHAF_01047 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MHCIJHAF_01048 2.01e-70 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MHCIJHAF_01049 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MHCIJHAF_01050 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MHCIJHAF_01051 1.99e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
MHCIJHAF_01052 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MHCIJHAF_01053 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHCIJHAF_01054 1.07e-79 yunG - - - - - - -
MHCIJHAF_01055 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
MHCIJHAF_01056 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MHCIJHAF_01057 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHCIJHAF_01058 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
MHCIJHAF_01059 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MHCIJHAF_01060 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MHCIJHAF_01061 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHCIJHAF_01062 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHCIJHAF_01063 3.2e-63 yutD - - S - - - protein conserved in bacteria
MHCIJHAF_01064 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
MHCIJHAF_01065 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHCIJHAF_01066 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MHCIJHAF_01067 1.55e-253 yutH - - S - - - Spore coat protein
MHCIJHAF_01068 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHCIJHAF_01069 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHCIJHAF_01070 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHCIJHAF_01071 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MHCIJHAF_01072 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MHCIJHAF_01073 5.44e-74 yuzD - - S - - - protein conserved in bacteria
MHCIJHAF_01074 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHCIJHAF_01075 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
MHCIJHAF_01076 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHCIJHAF_01077 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHCIJHAF_01078 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MHCIJHAF_01079 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_01080 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
MHCIJHAF_01081 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHCIJHAF_01083 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MHCIJHAF_01084 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHCIJHAF_01085 1.14e-45 yuiB - - S - - - Putative membrane protein
MHCIJHAF_01086 3.14e-149 yuiC - - S - - - protein conserved in bacteria
MHCIJHAF_01087 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MHCIJHAF_01088 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHCIJHAF_01089 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MHCIJHAF_01090 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MHCIJHAF_01091 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MHCIJHAF_01092 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
MHCIJHAF_01093 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_01094 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MHCIJHAF_01095 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MHCIJHAF_01096 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MHCIJHAF_01097 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_01098 8.23e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MHCIJHAF_01099 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MHCIJHAF_01100 3.3e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MHCIJHAF_01101 9.9e-291 yukF - - QT - - - Transcriptional regulator
MHCIJHAF_01102 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
MHCIJHAF_01103 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MHCIJHAF_01104 3.51e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MHCIJHAF_01105 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHCIJHAF_01106 0.0 yueB - - S - - - type VII secretion protein EsaA
MHCIJHAF_01107 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
MHCIJHAF_01108 1.01e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_01109 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MHCIJHAF_01110 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
MHCIJHAF_01111 1.82e-89 - - - S - - - Protein of unknown function (DUF2283)
MHCIJHAF_01112 2.73e-244 yueF - - S - - - transporter activity
MHCIJHAF_01113 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MHCIJHAF_01114 1.34e-51 yueH - - S - - - YueH-like protein
MHCIJHAF_01115 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
MHCIJHAF_01116 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MHCIJHAF_01117 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHCIJHAF_01118 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MHCIJHAF_01119 8.73e-09 yuzC - - - - - - -
MHCIJHAF_01121 6.29e-10 - - - S - - - DegQ (SacQ) family
MHCIJHAF_01122 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
MHCIJHAF_01124 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_01125 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_01126 1.11e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MHCIJHAF_01127 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MHCIJHAF_01128 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHCIJHAF_01129 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHCIJHAF_01130 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHCIJHAF_01131 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHCIJHAF_01132 8.95e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHCIJHAF_01133 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHCIJHAF_01134 1.42e-21 - - - - - - - -
MHCIJHAF_01135 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
MHCIJHAF_01136 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHCIJHAF_01137 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHCIJHAF_01138 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_01139 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MHCIJHAF_01140 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MHCIJHAF_01141 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHCIJHAF_01142 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
MHCIJHAF_01143 1.92e-97 yuxK - - S - - - protein conserved in bacteria
MHCIJHAF_01144 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MHCIJHAF_01145 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
MHCIJHAF_01147 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MHCIJHAF_01148 1.19e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MHCIJHAF_01149 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_01150 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHCIJHAF_01151 1.53e-52 yugE - - S - - - Domain of unknown function (DUF1871)
MHCIJHAF_01152 9.89e-201 yugF - - I - - - Hydrolase
MHCIJHAF_01153 6.74e-112 alaR - - K - - - Transcriptional regulator
MHCIJHAF_01154 5.2e-253 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MHCIJHAF_01155 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MHCIJHAF_01156 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MHCIJHAF_01157 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHCIJHAF_01158 6.49e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MHCIJHAF_01159 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHCIJHAF_01161 4.22e-95 yugN - - S - - - YugN-like family
MHCIJHAF_01162 1.02e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MHCIJHAF_01163 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
MHCIJHAF_01164 1.58e-50 - - - - - - - -
MHCIJHAF_01165 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MHCIJHAF_01166 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHCIJHAF_01167 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHCIJHAF_01168 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
MHCIJHAF_01169 1.44e-47 - - - - - - - -
MHCIJHAF_01170 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MHCIJHAF_01171 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_01172 1.86e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_01173 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_01174 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_01175 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
MHCIJHAF_01176 2.36e-171 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHCIJHAF_01177 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHCIJHAF_01178 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MHCIJHAF_01179 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
MHCIJHAF_01180 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MHCIJHAF_01181 1.73e-252 yubA - - S - - - transporter activity
MHCIJHAF_01182 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHCIJHAF_01184 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
MHCIJHAF_01185 0.0 yubD - - P - - - Major Facilitator Superfamily
MHCIJHAF_01186 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHCIJHAF_01187 3.31e-52 yubF - - S - - - yiaA/B two helix domain
MHCIJHAF_01188 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
MHCIJHAF_01189 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MHCIJHAF_01190 8.28e-118 yuaB - - - - - - -
MHCIJHAF_01191 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MHCIJHAF_01192 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHCIJHAF_01193 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MHCIJHAF_01194 3.5e-138 yuaD - - - - - - -
MHCIJHAF_01195 1.95e-109 yuaE - - S - - - DinB superfamily
MHCIJHAF_01196 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MHCIJHAF_01197 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MHCIJHAF_01198 1.2e-122 - - - M - - - FR47-like protein
MHCIJHAF_01199 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MHCIJHAF_01209 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MHCIJHAF_01216 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHCIJHAF_01217 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MHCIJHAF_01218 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHCIJHAF_01219 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MHCIJHAF_01220 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHCIJHAF_01221 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MHCIJHAF_01222 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MHCIJHAF_01223 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHCIJHAF_01224 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHCIJHAF_01225 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHCIJHAF_01226 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MHCIJHAF_01227 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHCIJHAF_01228 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHCIJHAF_01229 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHCIJHAF_01230 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MHCIJHAF_01231 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MHCIJHAF_01232 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHCIJHAF_01233 1.19e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHCIJHAF_01234 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHCIJHAF_01235 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHCIJHAF_01236 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHCIJHAF_01237 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHCIJHAF_01238 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHCIJHAF_01239 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCIJHAF_01240 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCIJHAF_01241 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MHCIJHAF_01242 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHCIJHAF_01243 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHCIJHAF_01244 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHCIJHAF_01245 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHCIJHAF_01246 1.5e-229 ybaC - - S - - - Alpha/beta hydrolase family
MHCIJHAF_01247 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHCIJHAF_01248 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHCIJHAF_01249 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHCIJHAF_01250 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHCIJHAF_01251 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHCIJHAF_01252 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHCIJHAF_01253 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHCIJHAF_01254 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHCIJHAF_01255 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHCIJHAF_01256 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHCIJHAF_01257 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHCIJHAF_01258 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHCIJHAF_01259 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHCIJHAF_01260 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHCIJHAF_01261 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHCIJHAF_01262 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHCIJHAF_01263 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHCIJHAF_01264 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHCIJHAF_01265 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHCIJHAF_01266 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHCIJHAF_01267 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MHCIJHAF_01268 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHCIJHAF_01269 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHCIJHAF_01270 4.68e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MHCIJHAF_01271 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHCIJHAF_01272 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MHCIJHAF_01273 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHCIJHAF_01274 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHCIJHAF_01275 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCIJHAF_01276 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHCIJHAF_01277 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCIJHAF_01278 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCIJHAF_01279 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCIJHAF_01280 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHCIJHAF_01281 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHCIJHAF_01282 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHCIJHAF_01283 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
MHCIJHAF_01284 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
MHCIJHAF_01285 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHCIJHAF_01286 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHCIJHAF_01287 1.04e-122 gerD - - - ko:K06294 - ko00000 -
MHCIJHAF_01288 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MHCIJHAF_01289 1.23e-180 pdaB - - G - - - Polysaccharide deacetylase
MHCIJHAF_01290 2.14e-232 yaaC - - S - - - YaaC-like Protein
MHCIJHAF_01291 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHCIJHAF_01292 2.16e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHCIJHAF_01293 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHCIJHAF_01294 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHCIJHAF_01295 6.6e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHCIJHAF_01297 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MHCIJHAF_01298 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MHCIJHAF_01299 2.11e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MHCIJHAF_01300 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MHCIJHAF_01301 3e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHCIJHAF_01302 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHCIJHAF_01303 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHCIJHAF_01304 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHCIJHAF_01305 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
MHCIJHAF_01306 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MHCIJHAF_01307 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MHCIJHAF_01324 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
MHCIJHAF_01325 3.88e-37 - - - - - - - -
MHCIJHAF_01326 4.02e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MHCIJHAF_01327 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHCIJHAF_01328 0.0 ygaK - - C - - - Berberine and berberine like
MHCIJHAF_01330 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHCIJHAF_01331 6.86e-184 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHCIJHAF_01332 1.7e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MHCIJHAF_01333 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHCIJHAF_01334 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MHCIJHAF_01336 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHCIJHAF_01337 2.79e-102 ygaO - - - - - - -
MHCIJHAF_01338 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_01340 1.92e-147 yhzB - - S - - - B3/4 domain
MHCIJHAF_01341 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHCIJHAF_01342 9.27e-224 yhbB - - S - - - Putative amidase domain
MHCIJHAF_01343 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHCIJHAF_01344 5.64e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
MHCIJHAF_01345 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MHCIJHAF_01346 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MHCIJHAF_01347 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MHCIJHAF_01348 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MHCIJHAF_01349 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MHCIJHAF_01350 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MHCIJHAF_01351 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHCIJHAF_01352 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
MHCIJHAF_01353 3.95e-59 yhcC - - - - - - -
MHCIJHAF_01354 1.18e-68 - - - - - - - -
MHCIJHAF_01355 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_01356 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_01357 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_01358 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHCIJHAF_01359 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MHCIJHAF_01360 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHCIJHAF_01361 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MHCIJHAF_01362 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHCIJHAF_01363 1.13e-70 yhcM - - - - - - -
MHCIJHAF_01364 6.46e-103 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHCIJHAF_01365 1.19e-195 yhcP - - - - - - -
MHCIJHAF_01366 1.68e-146 yhcQ - - M - - - Spore coat protein
MHCIJHAF_01367 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHCIJHAF_01368 1.52e-135 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MHCIJHAF_01369 2.76e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHCIJHAF_01370 2.47e-88 yhcU - - S - - - Family of unknown function (DUF5365)
MHCIJHAF_01371 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
MHCIJHAF_01372 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
MHCIJHAF_01373 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHCIJHAF_01374 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHCIJHAF_01375 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHCIJHAF_01376 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHCIJHAF_01377 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHCIJHAF_01378 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHCIJHAF_01379 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MHCIJHAF_01380 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_01381 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_01382 4.67e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MHCIJHAF_01383 1.65e-51 yhdB - - S - - - YhdB-like protein
MHCIJHAF_01384 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
MHCIJHAF_01385 5.63e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHCIJHAF_01386 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MHCIJHAF_01387 7.16e-305 ygxB - - M - - - Conserved TM helix
MHCIJHAF_01388 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MHCIJHAF_01389 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MHCIJHAF_01390 1.05e-199 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHCIJHAF_01391 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_01392 1.51e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHCIJHAF_01393 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_01394 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
MHCIJHAF_01395 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHCIJHAF_01396 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_01397 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_01398 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
MHCIJHAF_01399 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
MHCIJHAF_01400 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_01401 6.74e-244 yhdN - - C - - - Aldo keto reductase
MHCIJHAF_01402 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHCIJHAF_01403 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHCIJHAF_01404 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MHCIJHAF_01405 1.03e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHCIJHAF_01406 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MHCIJHAF_01407 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHCIJHAF_01408 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHCIJHAF_01409 7.42e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHCIJHAF_01410 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
MHCIJHAF_01411 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MHCIJHAF_01412 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHCIJHAF_01413 5.7e-200 nodB1 - - G - - - deacetylase
MHCIJHAF_01414 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHCIJHAF_01415 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MHCIJHAF_01416 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
MHCIJHAF_01417 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHCIJHAF_01418 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHCIJHAF_01419 3.31e-143 yheG - - GM - - - NAD(P)H-binding
MHCIJHAF_01420 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MHCIJHAF_01421 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
MHCIJHAF_01422 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MHCIJHAF_01423 1.6e-274 yheC - - HJ - - - YheC/D like ATP-grasp
MHCIJHAF_01424 4.85e-258 yheB - - S - - - Belongs to the UPF0754 family
MHCIJHAF_01425 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
MHCIJHAF_01426 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
MHCIJHAF_01427 1.24e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MHCIJHAF_01428 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MHCIJHAF_01429 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MHCIJHAF_01430 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MHCIJHAF_01432 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
MHCIJHAF_01433 2.29e-36 - - - S - - - YhzD-like protein
MHCIJHAF_01434 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_01435 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MHCIJHAF_01436 2.71e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MHCIJHAF_01437 0.0 yhaN - - L - - - AAA domain
MHCIJHAF_01438 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MHCIJHAF_01439 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
MHCIJHAF_01440 5.51e-173 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHCIJHAF_01441 3.3e-115 yhaK - - S - - - Putative zincin peptidase
MHCIJHAF_01442 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
MHCIJHAF_01443 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MHCIJHAF_01444 1.74e-54 yhaH - - S - - - YtxH-like protein
MHCIJHAF_01445 9.66e-30 - - - - - - - -
MHCIJHAF_01446 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
MHCIJHAF_01447 6.16e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHCIJHAF_01448 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHCIJHAF_01449 1.1e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MHCIJHAF_01450 7.32e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHCIJHAF_01451 3.37e-160 ecsC - - S - - - EcsC protein family
MHCIJHAF_01452 8.54e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHCIJHAF_01453 3.01e-309 yhfA - - C - - - membrane
MHCIJHAF_01454 8.22e-44 - - - C - - - Rubrerythrin
MHCIJHAF_01455 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MHCIJHAF_01456 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHCIJHAF_01457 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHCIJHAF_01458 2.4e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MHCIJHAF_01459 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHCIJHAF_01460 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_01461 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MHCIJHAF_01462 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHCIJHAF_01463 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
MHCIJHAF_01464 2.68e-253 yhfE - - G - - - peptidase M42
MHCIJHAF_01465 6.22e-93 - - - S - - - ASCH
MHCIJHAF_01466 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHCIJHAF_01467 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHCIJHAF_01468 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHCIJHAF_01469 3.02e-143 yhfK - - GM - - - NmrA-like family
MHCIJHAF_01470 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MHCIJHAF_01471 6.55e-84 yhfM - - - - - - -
MHCIJHAF_01472 3.92e-307 yhfN - - O - - - Peptidase M48
MHCIJHAF_01473 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCIJHAF_01474 2.96e-100 - - - K - - - acetyltransferase
MHCIJHAF_01475 8.03e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MHCIJHAF_01476 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MHCIJHAF_01477 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MHCIJHAF_01478 2.46e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHCIJHAF_01479 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MHCIJHAF_01480 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHCIJHAF_01481 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MHCIJHAF_01482 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MHCIJHAF_01483 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_01484 9.84e-45 yhzC - - S - - - IDEAL
MHCIJHAF_01485 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MHCIJHAF_01486 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_01487 3.27e-53 yhjA - - S - - - Excalibur calcium-binding domain
MHCIJHAF_01488 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCIJHAF_01489 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
MHCIJHAF_01490 2.57e-78 yhjD - - - - - - -
MHCIJHAF_01491 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
MHCIJHAF_01492 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHCIJHAF_01493 0.0 yhjG - - CH - - - FAD binding domain
MHCIJHAF_01494 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_01495 2.46e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MHCIJHAF_01496 9e-254 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHCIJHAF_01497 2.52e-203 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHCIJHAF_01498 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MHCIJHAF_01499 4.36e-239 yhjM - - K - - - Transcriptional regulator
MHCIJHAF_01500 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
MHCIJHAF_01501 1.93e-267 - - - EGP - - - Transmembrane secretion effector
MHCIJHAF_01502 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
MHCIJHAF_01503 1.29e-70 yhjQ - - C - - - COG1145 Ferredoxin
MHCIJHAF_01504 9.3e-102 yhjR - - S - - - Rubrerythrin
MHCIJHAF_01505 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MHCIJHAF_01506 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHCIJHAF_01507 5.69e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHCIJHAF_01508 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MHCIJHAF_01509 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
MHCIJHAF_01510 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MHCIJHAF_01511 3.35e-87 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MHCIJHAF_01512 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MHCIJHAF_01513 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MHCIJHAF_01514 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
MHCIJHAF_01515 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MHCIJHAF_01516 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
MHCIJHAF_01517 2.29e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
MHCIJHAF_01518 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHCIJHAF_01519 4.14e-74 yisL - - S - - - UPF0344 protein
MHCIJHAF_01520 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCIJHAF_01521 4.12e-129 yisN - - S - - - Protein of unknown function (DUF2777)
MHCIJHAF_01522 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHCIJHAF_01523 7.21e-105 yizA - - S - - - Damage-inducible protein DinB
MHCIJHAF_01524 4.6e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MHCIJHAF_01525 1.01e-310 yisQ - - V - - - Mate efflux family protein
MHCIJHAF_01526 3.88e-205 yisR - - K - - - Transcriptional regulator
MHCIJHAF_01527 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MHCIJHAF_01528 6.75e-245 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHCIJHAF_01529 4.92e-120 yisT - - S - - - DinB family
MHCIJHAF_01530 1.09e-139 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MHCIJHAF_01531 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_01532 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
MHCIJHAF_01533 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHCIJHAF_01534 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MHCIJHAF_01535 3.23e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MHCIJHAF_01536 3.87e-184 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MHCIJHAF_01537 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
MHCIJHAF_01538 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
MHCIJHAF_01539 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHCIJHAF_01540 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHCIJHAF_01541 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_01542 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
MHCIJHAF_01543 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
MHCIJHAF_01544 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHCIJHAF_01545 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MHCIJHAF_01546 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MHCIJHAF_01547 4.16e-122 - - - - - - - -
MHCIJHAF_01548 1.66e-217 - - - - - - - -
MHCIJHAF_01549 2.31e-127 - - - S - - - Sporulation delaying protein SdpA
MHCIJHAF_01550 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
MHCIJHAF_01551 1.29e-121 - - - - - - - -
MHCIJHAF_01552 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
MHCIJHAF_01553 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MHCIJHAF_01554 9.13e-202 yitS - - S - - - protein conserved in bacteria
MHCIJHAF_01555 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHCIJHAF_01556 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
MHCIJHAF_01557 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
MHCIJHAF_01558 1.92e-08 - - - - - - - -
MHCIJHAF_01559 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MHCIJHAF_01560 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHCIJHAF_01561 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MHCIJHAF_01562 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
MHCIJHAF_01563 8.36e-169 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MHCIJHAF_01564 8.82e-154 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MHCIJHAF_01565 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
MHCIJHAF_01566 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHCIJHAF_01567 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHCIJHAF_01568 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MHCIJHAF_01569 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MHCIJHAF_01570 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHCIJHAF_01571 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MHCIJHAF_01572 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHCIJHAF_01573 2.51e-39 yjzC - - S - - - YjzC-like protein
MHCIJHAF_01574 1.53e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
MHCIJHAF_01575 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
MHCIJHAF_01576 6.08e-131 yjaV - - - - - - -
MHCIJHAF_01577 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MHCIJHAF_01578 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MHCIJHAF_01579 2.67e-38 yjzB - - - - - - -
MHCIJHAF_01580 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHCIJHAF_01581 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHCIJHAF_01582 9.48e-193 yjaZ - - O - - - Zn-dependent protease
MHCIJHAF_01583 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_01584 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_01585 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MHCIJHAF_01586 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_01587 3.49e-196 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_01588 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
MHCIJHAF_01589 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MHCIJHAF_01590 6.74e-190 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHCIJHAF_01591 1.33e-187 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHCIJHAF_01592 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_01593 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_01594 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_01595 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_01596 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
MHCIJHAF_01597 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_01598 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHCIJHAF_01599 2.03e-143 yjbE - - P - - - Integral membrane protein TerC family
MHCIJHAF_01600 6.34e-147 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHCIJHAF_01601 1.03e-280 coiA - - S ko:K06198 - ko00000 Competence protein
MHCIJHAF_01602 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHCIJHAF_01603 2.68e-28 - - - - - - - -
MHCIJHAF_01605 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MHCIJHAF_01606 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MHCIJHAF_01607 2.94e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHCIJHAF_01608 7.32e-130 yjbK - - S - - - protein conserved in bacteria
MHCIJHAF_01609 3.77e-81 yjbL - - S - - - Belongs to the UPF0738 family
MHCIJHAF_01610 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MHCIJHAF_01611 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHCIJHAF_01612 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHCIJHAF_01613 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHCIJHAF_01614 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHCIJHAF_01615 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHCIJHAF_01616 5.7e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MHCIJHAF_01617 6.31e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MHCIJHAF_01618 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
MHCIJHAF_01619 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHCIJHAF_01620 7.21e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHCIJHAF_01621 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHCIJHAF_01622 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MHCIJHAF_01623 3.63e-104 yjbX - - S - - - Spore coat protein
MHCIJHAF_01624 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MHCIJHAF_01625 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MHCIJHAF_01626 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MHCIJHAF_01627 9.3e-32 cotW - - - ko:K06341 - ko00000 -
MHCIJHAF_01628 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MHCIJHAF_01629 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
MHCIJHAF_01632 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
MHCIJHAF_01633 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHCIJHAF_01634 6.31e-51 - - - - - - - -
MHCIJHAF_01635 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_01636 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MHCIJHAF_01637 1.83e-175 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MHCIJHAF_01639 1.87e-163 - - - V - - - COG1401 GTPase subunit of restriction endonuclease
MHCIJHAF_01640 8.47e-88 - - - - - - - -
MHCIJHAF_01641 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHCIJHAF_01642 2.14e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHCIJHAF_01643 2.05e-114 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MHCIJHAF_01644 1.37e-269 yjcL - - S - - - Protein of unknown function (DUF819)
MHCIJHAF_01647 3.75e-269 - - - S - - - Putative amidase domain
MHCIJHAF_01648 1.52e-68 yjcN - - - - - - -
MHCIJHAF_01650 2.15e-104 - - - L - - - Transposase
MHCIJHAF_01651 2.15e-104 - - - L - - - Transposase
MHCIJHAF_01660 5.58e-08 - - - S - - - YopX protein
MHCIJHAF_01662 1.13e-61 - - - S - - - dUTPase
MHCIJHAF_01668 2.74e-22 yqaO - - S - - - Phage-like element PBSX protein XtrA
MHCIJHAF_01670 2.59e-70 - - - S - - - Protein of unknown function (DUF1064)
MHCIJHAF_01673 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
MHCIJHAF_01674 3.61e-62 yqaL - - L - - - DnaD domain protein
MHCIJHAF_01676 1.17e-90 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MHCIJHAF_01677 3.41e-124 - - - - - - - -
MHCIJHAF_01682 2.56e-86 - - - - - - - -
MHCIJHAF_01683 7.49e-85 - - - S - - - DNA binding
MHCIJHAF_01684 9.71e-48 - - - - - - - -
MHCIJHAF_01685 5.56e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_01686 2.76e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_01687 6.58e-14 - - - S - - - Short C-terminal domain
MHCIJHAF_01688 5.82e-63 xkdA - - E - - - IrrE N-terminal-like domain
MHCIJHAF_01689 3.85e-182 - - - L - - - Belongs to the 'phage' integrase family
MHCIJHAF_01690 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHCIJHAF_01691 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHCIJHAF_01692 1.74e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCIJHAF_01693 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MHCIJHAF_01694 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHCIJHAF_01695 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHCIJHAF_01696 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHCIJHAF_01697 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHCIJHAF_01698 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MHCIJHAF_01699 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHCIJHAF_01700 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHCIJHAF_01701 2.4e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MHCIJHAF_01702 3.02e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MHCIJHAF_01703 1.05e-228 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MHCIJHAF_01707 2.15e-104 - - - L - - - Transposase
MHCIJHAF_01710 4.93e-125 yqaS - - L - - - DNA packaging
MHCIJHAF_01711 2.33e-282 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
MHCIJHAF_01712 4.64e-261 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHCIJHAF_01713 3.08e-116 - - - S - - - Phage Mu protein F like protein
MHCIJHAF_01716 2.94e-80 - - - S - - - Domain of unknown function (DUF4355)
MHCIJHAF_01717 1.11e-179 - - - S - - - Phage capsid family
MHCIJHAF_01720 1.91e-39 - - - S - - - Phage gp6-like head-tail connector protein
MHCIJHAF_01721 9.25e-37 - - - S - - - Phage head-tail joining protein
MHCIJHAF_01722 1.74e-47 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHCIJHAF_01723 1.4e-38 - - - S - - - Protein of unknown function (DUF3168)
MHCIJHAF_01724 1.49e-42 - - - S - - - Phage tail tube protein
MHCIJHAF_01725 5.17e-37 - - - S - - - Phage tail assembly chaperone protein, TAC
MHCIJHAF_01726 4.23e-188 - - - - - - - -
MHCIJHAF_01727 5.86e-12 - - - S - - - phage tail component
MHCIJHAF_01728 5.65e-277 - - - S - - - peptidoglycan catabolic process
MHCIJHAF_01733 1.56e-36 xhlA - - S - - - Haemolysin XhlA
MHCIJHAF_01734 4.54e-41 xhlB - - S - - - SPP1 phage holin
MHCIJHAF_01736 1.69e-179 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHCIJHAF_01738 2.75e-37 - - - K - - - Helix-turn-helix domain
MHCIJHAF_01739 2.14e-77 - - - S - - - guanosine tetraphosphate metabolic process
MHCIJHAF_01740 2.82e-117 - - - - - - - -
MHCIJHAF_01742 8.97e-192 ydjC - - S - - - Abhydrolase domain containing 18
MHCIJHAF_01743 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MHCIJHAF_01744 5.88e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MHCIJHAF_01745 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MHCIJHAF_01746 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHCIJHAF_01747 2.65e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MHCIJHAF_01748 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHCIJHAF_01749 2.2e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MHCIJHAF_01750 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MHCIJHAF_01751 3.77e-246 - - - S - - - Ion transport 2 domain protein
MHCIJHAF_01752 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCIJHAF_01753 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MHCIJHAF_01754 1.79e-84 ydjM - - M - - - Lytic transglycolase
MHCIJHAF_01755 3.59e-211 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MHCIJHAF_01757 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
MHCIJHAF_01758 3.45e-200 - - - I - - - Alpha/beta hydrolase family
MHCIJHAF_01759 2.49e-229 yeaA - - S - - - Protein of unknown function (DUF4003)
MHCIJHAF_01760 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MHCIJHAF_01761 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_01762 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHCIJHAF_01763 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MHCIJHAF_01764 4.55e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MHCIJHAF_01765 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MHCIJHAF_01766 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHCIJHAF_01767 6.85e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_01768 9.43e-314 - - - S - - - Domain of unknown function (DUF4179)
MHCIJHAF_01769 4.65e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MHCIJHAF_01770 2.78e-163 yebC - - M - - - Membrane
MHCIJHAF_01772 2.66e-120 yebE - - S - - - UPF0316 protein
MHCIJHAF_01773 3.13e-38 yebG - - S - - - NETI protein
MHCIJHAF_01774 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHCIJHAF_01775 1.28e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHCIJHAF_01776 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHCIJHAF_01777 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHCIJHAF_01778 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCIJHAF_01779 9.46e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCIJHAF_01780 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCIJHAF_01781 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHCIJHAF_01782 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHCIJHAF_01783 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHCIJHAF_01784 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHCIJHAF_01785 2.94e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHCIJHAF_01786 1.29e-94 - - - K - - - helix_turn_helix ASNC type
MHCIJHAF_01787 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MHCIJHAF_01788 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
MHCIJHAF_01789 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MHCIJHAF_01790 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MHCIJHAF_01791 7.62e-68 yerC - - S - - - protein conserved in bacteria
MHCIJHAF_01792 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MHCIJHAF_01793 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHCIJHAF_01794 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHCIJHAF_01795 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHCIJHAF_01796 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MHCIJHAF_01797 1.22e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MHCIJHAF_01798 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MHCIJHAF_01799 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCIJHAF_01800 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHCIJHAF_01801 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHCIJHAF_01802 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHCIJHAF_01803 1.26e-191 yerO - - K - - - Transcriptional regulator
MHCIJHAF_01804 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHCIJHAF_01805 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHCIJHAF_01806 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHCIJHAF_01807 7.52e-163 - - - - - - - -
MHCIJHAF_01808 7.55e-148 cll - - - - - - -
MHCIJHAF_01809 1.05e-47 - - - S - - - Plasmid maintenance system killer
MHCIJHAF_01810 4.02e-168 - - - K - - - Pfam:DUF955
MHCIJHAF_01812 2.26e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHCIJHAF_01814 2.42e-54 - - - S - - - Immunity protein 22
MHCIJHAF_01815 6.26e-230 - - - S - - - Bacterial EndoU nuclease
MHCIJHAF_01817 2.44e-127 - - - L - - - endonuclease activity
MHCIJHAF_01818 9.33e-160 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
MHCIJHAF_01819 4.2e-33 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
MHCIJHAF_01821 7.06e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
MHCIJHAF_01823 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
MHCIJHAF_01825 3.46e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_01826 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
MHCIJHAF_01827 1.23e-195 yesF - - GM - - - NAD(P)H-binding
MHCIJHAF_01828 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MHCIJHAF_01829 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
MHCIJHAF_01830 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MHCIJHAF_01831 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
MHCIJHAF_01833 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
MHCIJHAF_01834 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_01835 1.39e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
MHCIJHAF_01836 8.33e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHCIJHAF_01837 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_01838 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_01839 4.63e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
MHCIJHAF_01840 0.0 yesS - - K - - - Transcriptional regulator
MHCIJHAF_01841 9.4e-167 - - - E - - - GDSL-like Lipase/Acylhydrolase
MHCIJHAF_01842 1.25e-163 yesU - - S - - - Domain of unknown function (DUF1961)
MHCIJHAF_01843 3.86e-143 - - - S - - - Protein of unknown function, DUF624
MHCIJHAF_01844 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MHCIJHAF_01845 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MHCIJHAF_01846 6.17e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
MHCIJHAF_01847 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
MHCIJHAF_01848 0.0 yetA - - - - - - -
MHCIJHAF_01849 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHCIJHAF_01850 5.62e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MHCIJHAF_01851 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_01852 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MHCIJHAF_01853 1.49e-156 yetF - - S - - - membrane
MHCIJHAF_01854 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MHCIJHAF_01855 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_01856 1.75e-44 - - - - - - - -
MHCIJHAF_01857 1.2e-182 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHCIJHAF_01858 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
MHCIJHAF_01859 1.04e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MHCIJHAF_01860 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_01861 1.2e-263 yetM - - CH - - - FAD binding domain
MHCIJHAF_01862 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
MHCIJHAF_01863 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MHCIJHAF_01864 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MHCIJHAF_01865 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MHCIJHAF_01866 1.2e-237 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MHCIJHAF_01867 3.28e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MHCIJHAF_01868 1.16e-284 yfnE - - S - - - Glycosyltransferase like family 2
MHCIJHAF_01869 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MHCIJHAF_01870 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_01871 2.13e-167 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHCIJHAF_01872 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
MHCIJHAF_01873 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHCIJHAF_01874 1.47e-160 yfmS - - NT - - - chemotaxis protein
MHCIJHAF_01875 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHCIJHAF_01876 1.31e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MHCIJHAF_01877 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MHCIJHAF_01878 2.95e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MHCIJHAF_01879 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHCIJHAF_01880 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MHCIJHAF_01881 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
MHCIJHAF_01882 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MHCIJHAF_01883 3.46e-268 - - - G - - - Major Facilitator Superfamily
MHCIJHAF_01884 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
MHCIJHAF_01885 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHCIJHAF_01886 5.76e-221 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_01887 2.73e-219 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_01888 1.6e-218 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MHCIJHAF_01889 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
MHCIJHAF_01890 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
MHCIJHAF_01891 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MHCIJHAF_01892 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHCIJHAF_01893 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHCIJHAF_01894 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHCIJHAF_01895 1.14e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MHCIJHAF_01896 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MHCIJHAF_01897 3.43e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHCIJHAF_01898 4.79e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MHCIJHAF_01899 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHCIJHAF_01900 5.68e-156 yflK - - S - - - protein conserved in bacteria
MHCIJHAF_01901 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
MHCIJHAF_01902 2.82e-26 yflI - - - - - - -
MHCIJHAF_01903 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MHCIJHAF_01904 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MHCIJHAF_01905 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHCIJHAF_01906 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MHCIJHAF_01907 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MHCIJHAF_01908 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
MHCIJHAF_01909 3.61e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MHCIJHAF_01910 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_01911 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHCIJHAF_01912 5.05e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MHCIJHAF_01913 1.77e-159 frp - - C - - - nitroreductase
MHCIJHAF_01914 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHCIJHAF_01915 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MHCIJHAF_01916 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_01917 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
MHCIJHAF_01918 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHCIJHAF_01919 1.03e-66 yfkI - - S - - - gas vesicle protein
MHCIJHAF_01920 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHCIJHAF_01921 1.64e-12 - - - - - - - -
MHCIJHAF_01922 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_01923 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MHCIJHAF_01924 2.14e-188 yfkD - - S - - - YfkD-like protein
MHCIJHAF_01925 4.97e-188 yfkC - - M - - - Mechanosensitive ion channel
MHCIJHAF_01926 1.76e-283 yfkA - - S - - - YfkB-like domain
MHCIJHAF_01927 3.26e-36 yfjT - - - - - - -
MHCIJHAF_01928 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MHCIJHAF_01929 5.62e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHCIJHAF_01930 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MHCIJHAF_01931 7.91e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHCIJHAF_01932 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHCIJHAF_01933 3.04e-59 - - - S - - - YfzA-like protein
MHCIJHAF_01934 9.53e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHCIJHAF_01935 6.46e-109 yfjM - - S - - - Psort location Cytoplasmic, score
MHCIJHAF_01937 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHCIJHAF_01938 3.74e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHCIJHAF_01939 5.7e-263 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHCIJHAF_01940 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHCIJHAF_01941 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MHCIJHAF_01942 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MHCIJHAF_01943 1.38e-72 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
MHCIJHAF_01944 5.95e-113 - - - S - - - Family of unknown function (DUF5381)
MHCIJHAF_01945 4.33e-161 yfjC - - - - - - -
MHCIJHAF_01946 1.62e-239 yfjB - - - - - - -
MHCIJHAF_01947 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
MHCIJHAF_01948 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHCIJHAF_01949 2.49e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MHCIJHAF_01950 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_01951 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHCIJHAF_01952 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHCIJHAF_01953 3.34e-83 yfiD3 - - S - - - DoxX
MHCIJHAF_01954 4.21e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MHCIJHAF_01956 8.07e-271 baeS - - T - - - Histidine kinase
MHCIJHAF_01957 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MHCIJHAF_01958 1.94e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_01959 5.32e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHCIJHAF_01960 1.82e-257 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MHCIJHAF_01961 1.89e-128 padR - - K - - - transcriptional
MHCIJHAF_01962 1.3e-126 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHCIJHAF_01963 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MHCIJHAF_01964 3.3e-138 yfiR - - K - - - Transcriptional regulator
MHCIJHAF_01965 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
MHCIJHAF_01966 2.7e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MHCIJHAF_01967 0.0 yfiU - - EGP - - - the major facilitator superfamily
MHCIJHAF_01968 1.27e-104 yfiV - - K - - - transcriptional
MHCIJHAF_01969 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHCIJHAF_01970 1.1e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHCIJHAF_01971 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_01972 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_01973 7.61e-215 yfhB - - S - - - PhzF family
MHCIJHAF_01974 2.36e-137 yfhC - - C - - - nitroreductase
MHCIJHAF_01975 8.86e-35 yfhD - - S - - - YfhD-like protein
MHCIJHAF_01977 3.79e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MHCIJHAF_01978 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MHCIJHAF_01979 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
MHCIJHAF_01981 2.45e-268 yfhI - - EGP - - - -transporter
MHCIJHAF_01982 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
MHCIJHAF_01983 2.57e-59 yfhJ - - S - - - WVELL protein
MHCIJHAF_01984 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
MHCIJHAF_01985 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
MHCIJHAF_01986 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
MHCIJHAF_01987 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHCIJHAF_01988 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MHCIJHAF_01989 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MHCIJHAF_01990 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MHCIJHAF_01991 1.73e-48 yfhS - - - - - - -
MHCIJHAF_01992 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_01993 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MHCIJHAF_01994 2.01e-49 ygaB - - S - - - YgaB-like protein
MHCIJHAF_01995 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHCIJHAF_01996 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MHCIJHAF_01997 1.87e-238 ygaE - - S - - - Membrane
MHCIJHAF_01998 3.4e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MHCIJHAF_01999 8.36e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MHCIJHAF_02000 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHCIJHAF_02001 5.46e-74 ygzB - - S - - - UPF0295 protein
MHCIJHAF_02002 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
MHCIJHAF_02003 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MHCIJHAF_02005 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_02006 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_02008 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MHCIJHAF_02009 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHCIJHAF_02010 9.8e-313 yoeA - - V - - - MATE efflux family protein
MHCIJHAF_02011 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MHCIJHAF_02013 1.14e-124 - - - L - - - Integrase
MHCIJHAF_02014 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
MHCIJHAF_02015 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MHCIJHAF_02016 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02017 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHCIJHAF_02018 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHCIJHAF_02019 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MHCIJHAF_02020 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02021 4.51e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHCIJHAF_02022 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHCIJHAF_02023 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHCIJHAF_02024 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_02025 1.1e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
MHCIJHAF_02026 1.73e-172 yoxB - - - - - - -
MHCIJHAF_02027 2.81e-123 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHCIJHAF_02028 1.39e-164 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHCIJHAF_02029 1.25e-121 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHCIJHAF_02030 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHCIJHAF_02031 6.7e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_02032 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
MHCIJHAF_02033 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MHCIJHAF_02034 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCIJHAF_02035 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHCIJHAF_02036 7.24e-45 yoaF - - - - - - -
MHCIJHAF_02038 1.25e-20 - - - - - - - -
MHCIJHAF_02039 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
MHCIJHAF_02040 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
MHCIJHAF_02041 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MHCIJHAF_02042 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
MHCIJHAF_02043 1.79e-145 yoaK - - S - - - Membrane
MHCIJHAF_02044 3.38e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
MHCIJHAF_02045 4.18e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MHCIJHAF_02047 1.79e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MHCIJHAF_02050 1.08e-112 - - - - - - - -
MHCIJHAF_02051 1.48e-217 yoaR - - V - - - vancomycin resistance protein
MHCIJHAF_02052 2.65e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
MHCIJHAF_02053 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02054 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
MHCIJHAF_02055 6.67e-203 yoaU - - K - - - LysR substrate binding domain
MHCIJHAF_02056 1.83e-201 yoaV - - EG - - - EamA-like transporter family
MHCIJHAF_02057 5.63e-102 yoaW - - - - - - -
MHCIJHAF_02058 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
MHCIJHAF_02059 9.93e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MHCIJHAF_02063 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MHCIJHAF_02064 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MHCIJHAF_02066 6.27e-51 - - - S - - - TM2 domain
MHCIJHAF_02067 1.87e-74 - - - K - - - Helix-turn-helix
MHCIJHAF_02069 1.54e-84 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
MHCIJHAF_02070 1.48e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MHCIJHAF_02071 2.71e-29 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHCIJHAF_02072 2.59e-220 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHCIJHAF_02073 3.14e-167 - - - K - - - Bacterial regulatory proteins, lacI family
MHCIJHAF_02074 1.23e-272 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
MHCIJHAF_02076 5.09e-53 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHCIJHAF_02077 2.16e-128 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MHCIJHAF_02078 1.33e-141 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_02079 0.0 aga 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
MHCIJHAF_02080 1.09e-134 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MHCIJHAF_02081 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MHCIJHAF_02082 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHCIJHAF_02083 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
MHCIJHAF_02084 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
MHCIJHAF_02085 1.82e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MHCIJHAF_02086 6.36e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MHCIJHAF_02087 4.16e-180 - - - J - - - FR47-like protein
MHCIJHAF_02088 4.91e-124 yobS - - K - - - Transcriptional regulator
MHCIJHAF_02089 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHCIJHAF_02090 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
MHCIJHAF_02091 6.31e-224 yobV - - K - - - WYL domain
MHCIJHAF_02092 1.74e-119 yobW - - - - - - -
MHCIJHAF_02093 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MHCIJHAF_02094 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHCIJHAF_02095 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
MHCIJHAF_02096 2.39e-181 - - - - - - - -
MHCIJHAF_02097 2.99e-119 yocC - - - - - - -
MHCIJHAF_02098 2.62e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MHCIJHAF_02099 3.28e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MHCIJHAF_02100 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_02101 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_02102 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
MHCIJHAF_02103 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHCIJHAF_02104 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHCIJHAF_02105 4.07e-107 yocK - - T - - - general stress protein
MHCIJHAF_02106 3.02e-70 yocL - - - - - - -
MHCIJHAF_02107 7.29e-46 - - - - - - - -
MHCIJHAF_02108 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHCIJHAF_02109 2.94e-55 yozN - - - - - - -
MHCIJHAF_02110 1.83e-49 yocN - - - - - - -
MHCIJHAF_02111 2.17e-74 yozO - - S - - - Bacterial PH domain
MHCIJHAF_02112 1.91e-42 yozC - - - - - - -
MHCIJHAF_02113 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHCIJHAF_02114 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MHCIJHAF_02115 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MHCIJHAF_02116 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHCIJHAF_02117 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
MHCIJHAF_02118 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHCIJHAF_02119 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHCIJHAF_02120 0.0 yojO - - P - - - Von Willebrand factor
MHCIJHAF_02121 2.69e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MHCIJHAF_02122 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHCIJHAF_02123 6.16e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHCIJHAF_02124 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MHCIJHAF_02125 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHCIJHAF_02127 8.38e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MHCIJHAF_02128 1.68e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHCIJHAF_02129 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MHCIJHAF_02130 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MHCIJHAF_02131 1.85e-58 - - - - - - - -
MHCIJHAF_02132 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MHCIJHAF_02133 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MHCIJHAF_02134 5.59e-14 - - - - - - - -
MHCIJHAF_02135 2.65e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MHCIJHAF_02136 5.64e-84 iolK - - S - - - tautomerase
MHCIJHAF_02137 2.63e-73 yodB - - K - - - transcriptional
MHCIJHAF_02138 4.53e-139 yodC - - C - - - nitroreductase
MHCIJHAF_02139 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MHCIJHAF_02140 1.38e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHCIJHAF_02141 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
MHCIJHAF_02142 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCIJHAF_02143 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHCIJHAF_02144 3.69e-167 yodH - - Q - - - Methyltransferase
MHCIJHAF_02145 2.93e-42 yodI - - - - - - -
MHCIJHAF_02146 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MHCIJHAF_02147 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MHCIJHAF_02148 2.08e-12 - - - - - - - -
MHCIJHAF_02149 1.17e-71 yodL - - S - - - YodL-like
MHCIJHAF_02150 1.91e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHCIJHAF_02151 5.18e-34 yozD - - S - - - YozD-like protein
MHCIJHAF_02153 1.29e-159 yodN - - - - - - -
MHCIJHAF_02154 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
MHCIJHAF_02155 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
MHCIJHAF_02156 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MHCIJHAF_02157 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MHCIJHAF_02158 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MHCIJHAF_02159 4.49e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHCIJHAF_02160 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHCIJHAF_02161 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHCIJHAF_02163 1.56e-181 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MHCIJHAF_02164 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MHCIJHAF_02165 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
MHCIJHAF_02166 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
MHCIJHAF_02167 3.86e-236 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MHCIJHAF_02168 1.39e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MHCIJHAF_02169 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MHCIJHAF_02170 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHCIJHAF_02171 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHCIJHAF_02172 4.14e-94 ypoP - - K - - - transcriptional
MHCIJHAF_02173 5.77e-289 mepA - - V - - - MATE efflux family protein
MHCIJHAF_02174 2.13e-40 ypmT - - S - - - Uncharacterized ympT
MHCIJHAF_02175 1.95e-128 ypmS - - S - - - protein conserved in bacteria
MHCIJHAF_02176 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MHCIJHAF_02177 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHCIJHAF_02178 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
MHCIJHAF_02179 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHCIJHAF_02180 1.4e-236 yplP - - K - - - Transcriptional regulator
MHCIJHAF_02181 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MHCIJHAF_02182 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHCIJHAF_02183 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHCIJHAF_02184 2.34e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHCIJHAF_02185 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MHCIJHAF_02186 3.47e-148 ypjP - - S - - - YpjP-like protein
MHCIJHAF_02187 2.92e-185 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MHCIJHAF_02188 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
MHCIJHAF_02189 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MHCIJHAF_02190 1.34e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MHCIJHAF_02191 5.24e-135 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MHCIJHAF_02192 7.39e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MHCIJHAF_02193 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHCIJHAF_02194 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MHCIJHAF_02195 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MHCIJHAF_02196 1.17e-22 degR - - - - - - -
MHCIJHAF_02197 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
MHCIJHAF_02198 7.99e-41 ypeQ - - S - - - Zinc-finger
MHCIJHAF_02199 1.59e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MHCIJHAF_02200 1.62e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHCIJHAF_02201 1.08e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MHCIJHAF_02202 5.23e-05 - - - - ko:K06429 - ko00000 -
MHCIJHAF_02203 9.22e-213 ypcP - - L - - - 5'3' exonuclease
MHCIJHAF_02204 1.08e-11 - - - - - - - -
MHCIJHAF_02205 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
MHCIJHAF_02206 0.0 ypbR - - S - - - Dynamin family
MHCIJHAF_02207 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MHCIJHAF_02208 7.54e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MHCIJHAF_02209 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MHCIJHAF_02210 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHCIJHAF_02211 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHCIJHAF_02212 3.35e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MHCIJHAF_02213 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
MHCIJHAF_02214 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
MHCIJHAF_02215 1.19e-234 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
MHCIJHAF_02216 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MHCIJHAF_02217 4.44e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_02218 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MHCIJHAF_02220 9.72e-66 yqgA - - - - - - -
MHCIJHAF_02221 4.8e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHCIJHAF_02222 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHCIJHAF_02223 1.28e-125 ypsA - - S - - - Belongs to the UPF0398 family
MHCIJHAF_02224 1.63e-297 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MHCIJHAF_02225 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHCIJHAF_02226 1.58e-111 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MHCIJHAF_02227 2.06e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHCIJHAF_02228 8.72e-68 yppG - - S - - - YppG-like protein
MHCIJHAF_02229 9.21e-11 - - - S - - - YppF-like protein
MHCIJHAF_02230 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
MHCIJHAF_02233 5.3e-240 yppC - - S - - - Protein of unknown function (DUF2515)
MHCIJHAF_02234 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHCIJHAF_02235 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHCIJHAF_02236 1.43e-121 ypoC - - - - - - -
MHCIJHAF_02237 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHCIJHAF_02238 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MHCIJHAF_02239 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MHCIJHAF_02240 1.25e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHCIJHAF_02241 2.66e-102 ypmB - - S - - - protein conserved in bacteria
MHCIJHAF_02242 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MHCIJHAF_02243 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHCIJHAF_02244 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHCIJHAF_02245 3.03e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHCIJHAF_02246 1.39e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHCIJHAF_02247 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHCIJHAF_02248 2.14e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHCIJHAF_02249 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHCIJHAF_02250 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MHCIJHAF_02251 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MHCIJHAF_02252 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHCIJHAF_02253 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MHCIJHAF_02254 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHCIJHAF_02255 1.88e-180 ypjB - - S - - - sporulation protein
MHCIJHAF_02256 2.31e-125 ypjA - - S - - - membrane
MHCIJHAF_02257 2.33e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MHCIJHAF_02258 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MHCIJHAF_02259 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MHCIJHAF_02260 1.86e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
MHCIJHAF_02261 3.69e-129 ypiB - - S - - - Belongs to the UPF0302 family
MHCIJHAF_02262 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
MHCIJHAF_02263 1.11e-298 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHCIJHAF_02264 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MHCIJHAF_02265 1.5e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHCIJHAF_02266 2.21e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHCIJHAF_02267 8.95e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHCIJHAF_02268 3.7e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MHCIJHAF_02269 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MHCIJHAF_02270 8.28e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHCIJHAF_02271 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHCIJHAF_02272 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHCIJHAF_02273 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHCIJHAF_02274 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHCIJHAF_02275 5.24e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MHCIJHAF_02276 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHCIJHAF_02277 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHCIJHAF_02278 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHCIJHAF_02279 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHCIJHAF_02280 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHCIJHAF_02281 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MHCIJHAF_02282 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHCIJHAF_02283 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHCIJHAF_02284 8.71e-176 yphF - - - - - - -
MHCIJHAF_02285 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
MHCIJHAF_02286 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHCIJHAF_02287 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHCIJHAF_02288 8.69e-40 ypzH - - - - - - -
MHCIJHAF_02289 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
MHCIJHAF_02290 2.73e-134 yphA - - - - - - -
MHCIJHAF_02291 1.13e-11 - - - S - - - YpzI-like protein
MHCIJHAF_02292 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHCIJHAF_02293 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHCIJHAF_02294 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHCIJHAF_02295 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
MHCIJHAF_02296 2.2e-142 ypfA - - M - - - Flagellar protein YcgR
MHCIJHAF_02297 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
MHCIJHAF_02298 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MHCIJHAF_02299 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MHCIJHAF_02300 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MHCIJHAF_02301 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHCIJHAF_02302 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHCIJHAF_02303 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MHCIJHAF_02304 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
MHCIJHAF_02305 7.22e-137 ypbE - - M - - - Lysin motif
MHCIJHAF_02306 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MHCIJHAF_02307 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHCIJHAF_02308 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MHCIJHAF_02309 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MHCIJHAF_02310 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHCIJHAF_02311 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCIJHAF_02312 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHCIJHAF_02313 1.49e-254 rsiX - - - - - - -
MHCIJHAF_02314 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_02315 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_02316 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_02317 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHCIJHAF_02318 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MHCIJHAF_02319 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHCIJHAF_02320 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHCIJHAF_02321 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MHCIJHAF_02322 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MHCIJHAF_02323 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHCIJHAF_02324 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
MHCIJHAF_02325 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHCIJHAF_02326 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHCIJHAF_02327 5.92e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MHCIJHAF_02328 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_02329 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHCIJHAF_02330 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHCIJHAF_02331 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MHCIJHAF_02332 7.21e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHCIJHAF_02333 1.41e-70 ypuD - - - - - - -
MHCIJHAF_02334 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHCIJHAF_02335 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
MHCIJHAF_02336 1.61e-16 - - - S - - - SNARE associated Golgi protein
MHCIJHAF_02338 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHCIJHAF_02339 3.12e-192 ypuA - - S - - - Secreted protein
MHCIJHAF_02340 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHCIJHAF_02341 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MHCIJHAF_02342 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
MHCIJHAF_02343 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MHCIJHAF_02344 1.42e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MHCIJHAF_02345 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MHCIJHAF_02346 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MHCIJHAF_02347 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MHCIJHAF_02348 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_02349 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHCIJHAF_02350 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MHCIJHAF_02351 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHCIJHAF_02352 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHCIJHAF_02353 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHCIJHAF_02354 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MHCIJHAF_02355 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MHCIJHAF_02356 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHCIJHAF_02357 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHCIJHAF_02358 1.72e-40 yqkK - - - - - - -
MHCIJHAF_02359 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MHCIJHAF_02360 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MHCIJHAF_02361 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MHCIJHAF_02362 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MHCIJHAF_02363 3.18e-77 ansR - - K - - - Transcriptional regulator
MHCIJHAF_02364 6.16e-282 yqxK - - L - - - DNA helicase
MHCIJHAF_02365 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MHCIJHAF_02366 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
MHCIJHAF_02367 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MHCIJHAF_02368 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
MHCIJHAF_02369 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHCIJHAF_02370 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
MHCIJHAF_02371 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
MHCIJHAF_02372 9.27e-248 yqkA - - K - - - GrpB protein
MHCIJHAF_02373 6.44e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MHCIJHAF_02374 3.16e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MHCIJHAF_02375 5.37e-65 yqiX - - S - - - YolD-like protein
MHCIJHAF_02376 4.9e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHCIJHAF_02378 2.04e-289 yqjV - - G - - - Major Facilitator Superfamily
MHCIJHAF_02380 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_02381 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHCIJHAF_02382 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MHCIJHAF_02383 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_02384 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHCIJHAF_02385 1.13e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHCIJHAF_02386 0.0 rocB - - E - - - arginine degradation protein
MHCIJHAF_02387 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHCIJHAF_02388 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHCIJHAF_02389 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHCIJHAF_02390 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHCIJHAF_02391 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHCIJHAF_02392 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHCIJHAF_02393 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHCIJHAF_02394 1.77e-32 yqzJ - - - - - - -
MHCIJHAF_02395 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHCIJHAF_02396 6.93e-181 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
MHCIJHAF_02397 1.76e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MHCIJHAF_02398 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHCIJHAF_02399 3.84e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MHCIJHAF_02401 2.41e-128 yqjB - - S - - - protein conserved in bacteria
MHCIJHAF_02402 1.88e-225 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MHCIJHAF_02403 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHCIJHAF_02404 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHCIJHAF_02405 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHCIJHAF_02406 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
MHCIJHAF_02407 1.65e-211 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHCIJHAF_02408 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_02409 4.97e-175 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
MHCIJHAF_02410 6.52e-289 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHCIJHAF_02411 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHCIJHAF_02412 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHCIJHAF_02413 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHCIJHAF_02414 1.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MHCIJHAF_02415 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHCIJHAF_02416 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MHCIJHAF_02417 0.0 bkdR - - KT - - - Transcriptional regulator
MHCIJHAF_02418 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MHCIJHAF_02419 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHCIJHAF_02420 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MHCIJHAF_02421 4.75e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHCIJHAF_02422 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MHCIJHAF_02423 6.9e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MHCIJHAF_02424 1.34e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHCIJHAF_02425 4.29e-171 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHCIJHAF_02426 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MHCIJHAF_02427 4.74e-37 - - - - - - - -
MHCIJHAF_02428 1.54e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHCIJHAF_02430 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHCIJHAF_02431 1.47e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MHCIJHAF_02432 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHCIJHAF_02433 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHCIJHAF_02434 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MHCIJHAF_02435 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHCIJHAF_02436 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHCIJHAF_02437 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHCIJHAF_02438 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHCIJHAF_02439 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHCIJHAF_02440 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHCIJHAF_02441 1.65e-88 yqhY - - S - - - protein conserved in bacteria
MHCIJHAF_02442 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHCIJHAF_02443 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHCIJHAF_02444 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MHCIJHAF_02445 1.26e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MHCIJHAF_02446 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MHCIJHAF_02447 6.28e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MHCIJHAF_02448 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MHCIJHAF_02449 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MHCIJHAF_02450 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MHCIJHAF_02451 2.02e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MHCIJHAF_02452 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
MHCIJHAF_02453 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHCIJHAF_02454 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MHCIJHAF_02455 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MHCIJHAF_02456 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
MHCIJHAF_02457 5.16e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
MHCIJHAF_02458 5.18e-81 yqhP - - - - - - -
MHCIJHAF_02459 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MHCIJHAF_02460 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHCIJHAF_02461 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHCIJHAF_02462 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MHCIJHAF_02463 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHCIJHAF_02464 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHCIJHAF_02465 1.35e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MHCIJHAF_02466 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHCIJHAF_02467 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
MHCIJHAF_02468 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MHCIJHAF_02469 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MHCIJHAF_02470 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MHCIJHAF_02471 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MHCIJHAF_02472 1.76e-159 yqxM - - - ko:K19433 - ko00000 -
MHCIJHAF_02473 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
MHCIJHAF_02474 3.33e-35 yqzE - - S - - - YqzE-like protein
MHCIJHAF_02475 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MHCIJHAF_02476 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MHCIJHAF_02477 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MHCIJHAF_02478 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
MHCIJHAF_02479 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MHCIJHAF_02480 1.51e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MHCIJHAF_02481 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHCIJHAF_02483 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
MHCIJHAF_02484 7.17e-232 yqxL - - P - - - Mg2 transporter protein
MHCIJHAF_02485 5.77e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHCIJHAF_02486 2.49e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHCIJHAF_02488 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MHCIJHAF_02489 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MHCIJHAF_02490 1.07e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MHCIJHAF_02491 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
MHCIJHAF_02492 8.58e-65 yqgV - - S - - - Thiamine-binding protein
MHCIJHAF_02493 3.27e-257 yqgU - - - - - - -
MHCIJHAF_02494 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MHCIJHAF_02495 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MHCIJHAF_02496 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHCIJHAF_02497 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
MHCIJHAF_02498 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
MHCIJHAF_02499 3.38e-14 yqgO - - - - - - -
MHCIJHAF_02500 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHCIJHAF_02501 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHCIJHAF_02502 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
MHCIJHAF_02504 2.81e-67 yqzD - - - - - - -
MHCIJHAF_02505 1.09e-93 yqzC - - S - - - YceG-like family
MHCIJHAF_02506 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHCIJHAF_02507 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHCIJHAF_02508 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MHCIJHAF_02509 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHCIJHAF_02510 2.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHCIJHAF_02511 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MHCIJHAF_02512 1.32e-291 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MHCIJHAF_02513 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MHCIJHAF_02514 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MHCIJHAF_02515 1.87e-171 yqgB - - S - - - Protein of unknown function (DUF1189)
MHCIJHAF_02516 2.05e-99 yqgA - - - - - - -
MHCIJHAF_02517 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
MHCIJHAF_02518 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHCIJHAF_02519 2.04e-81 yqfX - - S - - - membrane
MHCIJHAF_02520 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MHCIJHAF_02521 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MHCIJHAF_02522 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHCIJHAF_02523 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MHCIJHAF_02524 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHCIJHAF_02525 4.45e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHCIJHAF_02526 4.89e-58 yqfQ - - S - - - YqfQ-like protein
MHCIJHAF_02527 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHCIJHAF_02528 3.77e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHCIJHAF_02529 4.66e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHCIJHAF_02530 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MHCIJHAF_02531 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHCIJHAF_02532 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHCIJHAF_02533 2.87e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MHCIJHAF_02534 1.29e-190 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHCIJHAF_02535 3.29e-144 ccpN - - K - - - CBS domain
MHCIJHAF_02536 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHCIJHAF_02537 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHCIJHAF_02538 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHCIJHAF_02539 5.29e-27 - - - S - - - YqzL-like protein
MHCIJHAF_02540 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHCIJHAF_02541 2.73e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHCIJHAF_02542 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHCIJHAF_02543 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHCIJHAF_02544 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MHCIJHAF_02546 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MHCIJHAF_02547 9.93e-241 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MHCIJHAF_02548 2.07e-60 yqfC - - S - - - sporulation protein YqfC
MHCIJHAF_02549 3.5e-53 yqfB - - - - - - -
MHCIJHAF_02550 4.35e-192 yqfA - - S - - - UPF0365 protein
MHCIJHAF_02551 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MHCIJHAF_02552 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MHCIJHAF_02553 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHCIJHAF_02554 4.9e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MHCIJHAF_02555 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MHCIJHAF_02556 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHCIJHAF_02557 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MHCIJHAF_02558 9.76e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHCIJHAF_02559 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHCIJHAF_02560 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHCIJHAF_02561 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHCIJHAF_02562 1.23e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MHCIJHAF_02563 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHCIJHAF_02564 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
MHCIJHAF_02565 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MHCIJHAF_02566 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHCIJHAF_02567 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHCIJHAF_02568 4.74e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHCIJHAF_02569 2.36e-22 - - - S - - - YqzM-like protein
MHCIJHAF_02570 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHCIJHAF_02571 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHCIJHAF_02572 1.57e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MHCIJHAF_02573 9e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHCIJHAF_02574 5.67e-178 yqeM - - Q - - - Methyltransferase
MHCIJHAF_02575 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHCIJHAF_02576 6.56e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MHCIJHAF_02577 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHCIJHAF_02578 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MHCIJHAF_02579 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHCIJHAF_02580 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHCIJHAF_02581 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MHCIJHAF_02583 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MHCIJHAF_02584 5.41e-173 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MHCIJHAF_02585 3.27e-135 yqeD - - S - - - SNARE associated Golgi protein
MHCIJHAF_02586 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
MHCIJHAF_02587 9.38e-171 - - - - - - - -
MHCIJHAF_02588 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
MHCIJHAF_02589 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_02590 0.0 - - - L ko:K06400 - ko00000 Recombinase
MHCIJHAF_02591 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MHCIJHAF_02592 1.18e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
MHCIJHAF_02593 3.34e-91 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCIJHAF_02594 2.17e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
MHCIJHAF_02595 1.7e-187 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MHCIJHAF_02596 8.68e-120 - - - S - - - Tetratricopeptide repeat
MHCIJHAF_02599 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
MHCIJHAF_02600 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
MHCIJHAF_02602 5.4e-80 - - - - - - - -
MHCIJHAF_02604 8.93e-183 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHCIJHAF_02605 5.65e-87 - - - S - - - Bacteriophage holin family
MHCIJHAF_02606 1.46e-205 xepA - - - - - - -
MHCIJHAF_02607 9.34e-33 - - - - - - - -
MHCIJHAF_02608 1.01e-73 xkdW - - S - - - XkdW protein
MHCIJHAF_02609 1.19e-282 - - - - - - - -
MHCIJHAF_02610 8.29e-52 - - - - - - - -
MHCIJHAF_02611 9.55e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MHCIJHAF_02612 3.86e-238 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHCIJHAF_02613 1.75e-86 xkdS - - S - - - Protein of unknown function (DUF2634)
MHCIJHAF_02614 4.54e-48 xkdR - - S - - - Protein of unknown function (DUF2577)
MHCIJHAF_02615 1.81e-225 xkdQ - - G - - - NLP P60 protein
MHCIJHAF_02616 3.12e-154 xkdP - - S - - - Lysin motif
MHCIJHAF_02617 0.0 xkdO - - L - - - Transglycosylase SLT domain
MHCIJHAF_02618 1.58e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MHCIJHAF_02620 4.23e-99 xkdM - - S - - - Phage tail tube protein
MHCIJHAF_02621 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
MHCIJHAF_02622 2.52e-36 - - - - - - - -
MHCIJHAF_02623 3.24e-102 yqbJ - - - - - - -
MHCIJHAF_02624 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHCIJHAF_02625 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
MHCIJHAF_02626 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
MHCIJHAF_02627 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
MHCIJHAF_02628 9.21e-216 xkdG - - S - - - Phage capsid family
MHCIJHAF_02629 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
MHCIJHAF_02630 2.13e-149 - - - - - - - -
MHCIJHAF_02631 1.73e-217 - - - S - - - Phage Mu protein F like protein
MHCIJHAF_02632 0.0 yqbA - - S - - - portal protein
MHCIJHAF_02633 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
MHCIJHAF_02634 2.02e-158 yqaS - - L - - - DNA packaging
MHCIJHAF_02636 1.58e-105 yqaQ - - L - - - Transposase
MHCIJHAF_02637 7.56e-214 - - - - - - - -
MHCIJHAF_02638 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
MHCIJHAF_02639 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
MHCIJHAF_02641 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
MHCIJHAF_02642 1.92e-158 yqaL - - L - - - DnaD domain protein
MHCIJHAF_02643 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
MHCIJHAF_02644 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
MHCIJHAF_02648 1.27e-134 - - - - - - - -
MHCIJHAF_02650 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_02651 1.25e-74 - - - K - - - sequence-specific DNA binding
MHCIJHAF_02653 8.73e-132 yqaC - - F - - - adenylate kinase activity
MHCIJHAF_02654 1.58e-122 xkdA - - E - - - IrrE N-terminal-like domain
MHCIJHAF_02655 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_02656 1.94e-145 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
MHCIJHAF_02657 1.17e-181 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
MHCIJHAF_02658 8.7e-71 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
MHCIJHAF_02659 1.26e-207 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHCIJHAF_02660 1.15e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
MHCIJHAF_02661 1.3e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
MHCIJHAF_02662 4.67e-260 yrkH - - P - - - Rhodanese Homology Domain
MHCIJHAF_02663 1.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
MHCIJHAF_02664 3.25e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
MHCIJHAF_02665 4.38e-52 yrkD - - S - - - protein conserved in bacteria
MHCIJHAF_02666 1.05e-136 yrkC - - G - - - Cupin domain
MHCIJHAF_02667 3.56e-194 bltR - - K - - - helix_turn_helix, mercury resistance
MHCIJHAF_02668 1.26e-267 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_02669 7.52e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MHCIJHAF_02670 1.52e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHCIJHAF_02671 2.45e-23 - - - S - - - YrzO-like protein
MHCIJHAF_02672 1.26e-218 yrdR - - EG - - - EamA-like transporter family
MHCIJHAF_02673 2.83e-203 - - - K - - - Transcriptional regulator
MHCIJHAF_02674 2.48e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
MHCIJHAF_02675 3.68e-206 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MHCIJHAF_02676 1.01e-86 yodA - - S - - - tautomerase
MHCIJHAF_02677 4.97e-150 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MHCIJHAF_02678 3.01e-293 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHCIJHAF_02679 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
MHCIJHAF_02680 9.34e-176 azlC - - E - - - AzlC protein
MHCIJHAF_02681 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
MHCIJHAF_02682 4.64e-44 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MHCIJHAF_02683 2.38e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHCIJHAF_02684 4.27e-132 yrdC - - Q - - - Isochorismatase family
MHCIJHAF_02685 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
MHCIJHAF_02686 5.77e-118 yrdA - - S - - - DinB family
MHCIJHAF_02687 3.62e-213 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MHCIJHAF_02688 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHCIJHAF_02689 1.02e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHCIJHAF_02690 1.14e-160 yrpD - - S - - - Domain of unknown function, YrpD
MHCIJHAF_02692 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MHCIJHAF_02693 6.39e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_02694 1.15e-237 yrpG - - C - - - Aldo/keto reductase family
MHCIJHAF_02695 1.45e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MHCIJHAF_02696 2.97e-210 yraN - - K - - - Transcriptional regulator
MHCIJHAF_02697 5.95e-263 yraM - - S - - - PrpF protein
MHCIJHAF_02699 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MHCIJHAF_02700 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHCIJHAF_02701 4.9e-200 - - - S - - - Alpha beta hydrolase
MHCIJHAF_02702 6.61e-80 - - - T - - - sh3 domain protein
MHCIJHAF_02703 2.92e-81 - - - T - - - sh3 domain protein
MHCIJHAF_02704 6.62e-87 - - - E - - - Glyoxalase-like domain
MHCIJHAF_02705 4.19e-50 yraG - - - ko:K06440 - ko00000 -
MHCIJHAF_02706 9.61e-84 yraF - - M - - - Spore coat protein
MHCIJHAF_02707 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHCIJHAF_02708 1.05e-36 yraE - - - ko:K06440 - ko00000 -
MHCIJHAF_02709 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
MHCIJHAF_02710 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MHCIJHAF_02711 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
MHCIJHAF_02712 4.12e-254 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MHCIJHAF_02713 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MHCIJHAF_02714 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MHCIJHAF_02715 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MHCIJHAF_02716 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MHCIJHAF_02717 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
MHCIJHAF_02718 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHCIJHAF_02719 0.0 levR - - K - - - PTS system fructose IIA component
MHCIJHAF_02720 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_02721 5.63e-137 yrhP - - E - - - LysE type translocator
MHCIJHAF_02722 8.04e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
MHCIJHAF_02723 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_02724 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
MHCIJHAF_02725 0.0 oatA - - I - - - Acyltransferase family
MHCIJHAF_02726 5.19e-60 yrhK - - S - - - YrhK-like protein
MHCIJHAF_02727 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MHCIJHAF_02728 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MHCIJHAF_02729 1.5e-124 yrhH - - Q - - - methyltransferase
MHCIJHAF_02730 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MHCIJHAF_02732 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MHCIJHAF_02734 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MHCIJHAF_02735 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MHCIJHAF_02736 4.97e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
MHCIJHAF_02737 6.93e-49 yrhC - - S - - - YrhC-like protein
MHCIJHAF_02738 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHCIJHAF_02739 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MHCIJHAF_02740 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHCIJHAF_02741 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHCIJHAF_02742 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
MHCIJHAF_02743 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
MHCIJHAF_02744 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MHCIJHAF_02745 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHCIJHAF_02746 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHCIJHAF_02747 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MHCIJHAF_02748 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MHCIJHAF_02749 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MHCIJHAF_02750 1.24e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHCIJHAF_02751 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
MHCIJHAF_02752 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHCIJHAF_02753 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
MHCIJHAF_02754 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHCIJHAF_02755 3.07e-242 yrrI - - S - - - AI-2E family transporter
MHCIJHAF_02756 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHCIJHAF_02757 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHCIJHAF_02758 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCIJHAF_02759 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCIJHAF_02760 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
MHCIJHAF_02761 8.4e-42 yrzR - - - - - - -
MHCIJHAF_02762 1.23e-108 yrrD - - S - - - protein conserved in bacteria
MHCIJHAF_02763 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHCIJHAF_02764 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
MHCIJHAF_02765 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHCIJHAF_02766 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHCIJHAF_02767 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02768 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHCIJHAF_02769 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHCIJHAF_02770 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHCIJHAF_02771 5.19e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHCIJHAF_02773 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MHCIJHAF_02774 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHCIJHAF_02775 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHCIJHAF_02776 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHCIJHAF_02777 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHCIJHAF_02778 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MHCIJHAF_02779 3.77e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MHCIJHAF_02780 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHCIJHAF_02781 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
MHCIJHAF_02782 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_02783 1.23e-144 yrbG - - S - - - membrane
MHCIJHAF_02784 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
MHCIJHAF_02785 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MHCIJHAF_02786 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHCIJHAF_02787 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHCIJHAF_02788 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
MHCIJHAF_02789 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHCIJHAF_02790 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHCIJHAF_02791 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MHCIJHAF_02792 0.0 csbX - - EGP - - - the major facilitator superfamily
MHCIJHAF_02793 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MHCIJHAF_02794 3.17e-150 yrzF - - T - - - serine threonine protein kinase
MHCIJHAF_02796 1.47e-66 - - - S - - - Family of unknown function (DUF5412)
MHCIJHAF_02797 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
MHCIJHAF_02798 2.37e-162 yebC - - K - - - transcriptional regulatory protein
MHCIJHAF_02799 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHCIJHAF_02800 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MHCIJHAF_02801 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHCIJHAF_02802 4.34e-203 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MHCIJHAF_02803 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MHCIJHAF_02804 6.49e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHCIJHAF_02805 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MHCIJHAF_02806 2.89e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MHCIJHAF_02807 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MHCIJHAF_02808 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHCIJHAF_02809 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MHCIJHAF_02810 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHCIJHAF_02811 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MHCIJHAF_02812 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHCIJHAF_02813 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MHCIJHAF_02814 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MHCIJHAF_02815 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHCIJHAF_02816 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHCIJHAF_02817 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MHCIJHAF_02818 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHCIJHAF_02819 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MHCIJHAF_02820 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MHCIJHAF_02821 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MHCIJHAF_02822 7.4e-212 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MHCIJHAF_02823 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHCIJHAF_02824 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHCIJHAF_02825 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHCIJHAF_02826 1.53e-35 - - - - - - - -
MHCIJHAF_02827 3.26e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHCIJHAF_02828 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MHCIJHAF_02829 2.04e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MHCIJHAF_02830 1.51e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MHCIJHAF_02831 2.91e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MHCIJHAF_02832 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHCIJHAF_02833 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MHCIJHAF_02834 2.74e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHCIJHAF_02835 3.35e-116 ysxD - - - - - - -
MHCIJHAF_02836 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHCIJHAF_02837 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHCIJHAF_02838 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MHCIJHAF_02839 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHCIJHAF_02840 7.28e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHCIJHAF_02841 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
MHCIJHAF_02842 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHCIJHAF_02843 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHCIJHAF_02844 7.43e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHCIJHAF_02845 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHCIJHAF_02846 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHCIJHAF_02847 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MHCIJHAF_02848 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MHCIJHAF_02850 3.28e-46 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MHCIJHAF_02851 1.01e-184 ysnF - - S - - - protein conserved in bacteria
MHCIJHAF_02853 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHCIJHAF_02854 1.24e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHCIJHAF_02855 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHCIJHAF_02856 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MHCIJHAF_02857 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHCIJHAF_02858 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_02859 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02860 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MHCIJHAF_02861 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MHCIJHAF_02862 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MHCIJHAF_02863 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MHCIJHAF_02864 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
MHCIJHAF_02865 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHCIJHAF_02866 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHCIJHAF_02867 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHCIJHAF_02868 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MHCIJHAF_02870 7.11e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MHCIJHAF_02871 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MHCIJHAF_02872 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MHCIJHAF_02873 3.46e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_02874 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHCIJHAF_02875 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
MHCIJHAF_02876 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHCIJHAF_02877 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MHCIJHAF_02878 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
MHCIJHAF_02879 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHCIJHAF_02880 1.47e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHCIJHAF_02881 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHCIJHAF_02882 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHCIJHAF_02883 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHCIJHAF_02884 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MHCIJHAF_02885 2.51e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MHCIJHAF_02886 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
MHCIJHAF_02887 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MHCIJHAF_02888 5.13e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
MHCIJHAF_02889 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MHCIJHAF_02890 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MHCIJHAF_02891 3.01e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MHCIJHAF_02892 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MHCIJHAF_02893 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MHCIJHAF_02894 1.92e-284 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MHCIJHAF_02895 1.74e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MHCIJHAF_02896 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHCIJHAF_02897 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MHCIJHAF_02898 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MHCIJHAF_02899 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MHCIJHAF_02900 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MHCIJHAF_02901 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
MHCIJHAF_02902 1.27e-59 ysdA - - S - - - Membrane
MHCIJHAF_02903 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHCIJHAF_02904 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHCIJHAF_02905 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHCIJHAF_02907 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHCIJHAF_02908 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHCIJHAF_02909 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MHCIJHAF_02910 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_02911 3.43e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MHCIJHAF_02912 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHCIJHAF_02913 2e-204 ytxC - - S - - - YtxC-like family
MHCIJHAF_02914 5.65e-143 ytxB - - S - - - SNARE associated Golgi protein
MHCIJHAF_02915 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHCIJHAF_02916 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MHCIJHAF_02917 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHCIJHAF_02918 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHCIJHAF_02919 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHCIJHAF_02920 9.85e-88 ytcD - - K - - - Transcriptional regulator
MHCIJHAF_02921 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MHCIJHAF_02922 4.54e-205 ytbE - - S - - - reductase
MHCIJHAF_02923 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHCIJHAF_02924 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
MHCIJHAF_02925 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHCIJHAF_02926 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHCIJHAF_02927 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MHCIJHAF_02928 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_02929 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MHCIJHAF_02930 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MHCIJHAF_02931 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHCIJHAF_02932 9.38e-95 ytwI - - S - - - membrane
MHCIJHAF_02933 6.42e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
MHCIJHAF_02934 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHCIJHAF_02935 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHCIJHAF_02936 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHCIJHAF_02937 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHCIJHAF_02938 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHCIJHAF_02939 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MHCIJHAF_02940 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHCIJHAF_02941 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
MHCIJHAF_02942 5.98e-111 ytrI - - - - - - -
MHCIJHAF_02943 1.15e-39 - - - - - - - -
MHCIJHAF_02944 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MHCIJHAF_02945 2.15e-63 ytpI - - S - - - YtpI-like protein
MHCIJHAF_02946 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
MHCIJHAF_02947 2.5e-203 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
MHCIJHAF_02948 1.41e-304 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MHCIJHAF_02949 9.41e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
MHCIJHAF_02950 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_02951 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MHCIJHAF_02952 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_02953 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHCIJHAF_02954 7.89e-154 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_02955 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCIJHAF_02956 6.27e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MHCIJHAF_02957 7.48e-194 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MHCIJHAF_02958 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHCIJHAF_02959 1.67e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MHCIJHAF_02960 4.53e-166 ytkL - - S - - - Belongs to the UPF0173 family
MHCIJHAF_02961 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_02963 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHCIJHAF_02964 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHCIJHAF_02965 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MHCIJHAF_02966 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHCIJHAF_02967 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MHCIJHAF_02968 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHCIJHAF_02969 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
MHCIJHAF_02970 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
MHCIJHAF_02971 7.05e-113 yteJ - - S - - - RDD family
MHCIJHAF_02972 2.49e-232 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MHCIJHAF_02973 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHCIJHAF_02974 0.0 ytcJ - - S - - - amidohydrolase
MHCIJHAF_02975 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHCIJHAF_02976 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MHCIJHAF_02977 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHCIJHAF_02978 5.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHCIJHAF_02979 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHCIJHAF_02980 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHCIJHAF_02981 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MHCIJHAF_02982 2.94e-142 yttP - - K - - - Transcriptional regulator
MHCIJHAF_02983 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHCIJHAF_02984 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MHCIJHAF_02985 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHCIJHAF_02987 4.36e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHCIJHAF_02988 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHCIJHAF_02989 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHCIJHAF_02990 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MHCIJHAF_02991 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MHCIJHAF_02992 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MHCIJHAF_02993 3.96e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MHCIJHAF_02994 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHCIJHAF_02995 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHCIJHAF_02996 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
MHCIJHAF_02997 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MHCIJHAF_02998 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHCIJHAF_02999 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHCIJHAF_03000 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHCIJHAF_03001 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHCIJHAF_03002 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
MHCIJHAF_03003 9.1e-75 ytpP - - CO - - - Thioredoxin
MHCIJHAF_03004 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MHCIJHAF_03005 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MHCIJHAF_03006 1.17e-67 ytzB - - S - - - small secreted protein
MHCIJHAF_03007 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MHCIJHAF_03008 3.07e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHCIJHAF_03009 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHCIJHAF_03010 9.51e-61 ytzH - - S - - - YtzH-like protein
MHCIJHAF_03011 3.02e-192 ytmP - - M - - - Phosphotransferase
MHCIJHAF_03012 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHCIJHAF_03013 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHCIJHAF_03014 4.92e-212 ytlQ - - - - - - -
MHCIJHAF_03015 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHCIJHAF_03016 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHCIJHAF_03017 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MHCIJHAF_03018 1.65e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MHCIJHAF_03019 4.1e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MHCIJHAF_03020 1.62e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHCIJHAF_03021 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MHCIJHAF_03022 1.23e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHCIJHAF_03023 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_03024 1.41e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MHCIJHAF_03025 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MHCIJHAF_03026 2.14e-36 yteV - - S - - - Sporulation protein Cse60
MHCIJHAF_03027 2.3e-151 yteU - - S - - - Integral membrane protein
MHCIJHAF_03028 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MHCIJHAF_03029 5.81e-95 yteS - - G - - - transport
MHCIJHAF_03030 7.96e-277 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MHCIJHAF_03031 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MHCIJHAF_03032 0.0 ytdP - - K - - - Transcriptional regulator
MHCIJHAF_03033 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MHCIJHAF_03034 4.17e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MHCIJHAF_03035 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
MHCIJHAF_03036 4.38e-286 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHCIJHAF_03037 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHCIJHAF_03038 1.55e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MHCIJHAF_03039 3.15e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHCIJHAF_03040 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MHCIJHAF_03041 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MHCIJHAF_03042 1.87e-218 - - - S - - - Acetyl xylan esterase (AXE1)
MHCIJHAF_03043 2.64e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_03044 1.89e-314 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHCIJHAF_03045 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCIJHAF_03046 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MHCIJHAF_03047 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MHCIJHAF_03048 1.22e-68 ytwF - - P - - - Sulfurtransferase
MHCIJHAF_03049 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHCIJHAF_03050 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
MHCIJHAF_03051 1.1e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MHCIJHAF_03052 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
MHCIJHAF_03053 4.46e-56 yttA - - S - - - Pfam Transposase IS66
MHCIJHAF_03054 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MHCIJHAF_03055 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03056 6.44e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MHCIJHAF_03057 7.76e-168 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_03058 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MHCIJHAF_03059 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03060 9.19e-191 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MHCIJHAF_03061 6.58e-197 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHCIJHAF_03062 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03063 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MHCIJHAF_03065 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
MHCIJHAF_03066 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MHCIJHAF_03067 1.59e-135 ytqB - - J - - - Putative rRNA methylase
MHCIJHAF_03068 1.61e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MHCIJHAF_03069 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MHCIJHAF_03070 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHCIJHAF_03071 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_03072 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHCIJHAF_03073 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHCIJHAF_03074 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHCIJHAF_03075 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MHCIJHAF_03076 1.06e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHCIJHAF_03077 9.28e-241 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHCIJHAF_03078 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHCIJHAF_03079 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHCIJHAF_03080 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MHCIJHAF_03081 1.59e-81 ytkC - - S - - - Bacteriophage holin family
MHCIJHAF_03082 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MHCIJHAF_03084 6.79e-95 ytkA - - S - - - YtkA-like
MHCIJHAF_03085 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHCIJHAF_03086 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MHCIJHAF_03087 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHCIJHAF_03088 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MHCIJHAF_03089 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHCIJHAF_03090 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MHCIJHAF_03091 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MHCIJHAF_03092 3.03e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHCIJHAF_03093 6.86e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHCIJHAF_03094 2.65e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHCIJHAF_03095 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHCIJHAF_03096 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHCIJHAF_03097 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHCIJHAF_03098 1.34e-194 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHCIJHAF_03099 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHCIJHAF_03100 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MHCIJHAF_03101 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
MHCIJHAF_03102 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MHCIJHAF_03103 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHCIJHAF_03104 2.59e-229 ytcB - - M - - - NAD-dependent epimerase dehydratase
MHCIJHAF_03105 3.4e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
MHCIJHAF_03107 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
MHCIJHAF_03108 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
MHCIJHAF_03109 1.83e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
MHCIJHAF_03110 1.3e-53 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MHCIJHAF_03111 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHCIJHAF_03112 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHCIJHAF_03113 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
MHCIJHAF_03114 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHCIJHAF_03115 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHCIJHAF_03138 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_03139 6.05e-86 hxlR - - K - - - transcriptional
MHCIJHAF_03140 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MHCIJHAF_03141 6.55e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MHCIJHAF_03142 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_03143 1e-93 nucA - - M - - - Deoxyribonuclease NucA/NucB
MHCIJHAF_03144 4.78e-91 nin - - S - - - Competence protein J (ComJ)
MHCIJHAF_03145 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCIJHAF_03146 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
MHCIJHAF_03147 2.24e-96 yckC - - S - - - membrane
MHCIJHAF_03150 2.08e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MHCIJHAF_03151 1.22e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHCIJHAF_03152 2.65e-288 yciC - - S - - - GTPases (G3E family)
MHCIJHAF_03153 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
MHCIJHAF_03154 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
MHCIJHAF_03155 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MHCIJHAF_03156 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
MHCIJHAF_03157 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHCIJHAF_03158 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MHCIJHAF_03159 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MHCIJHAF_03160 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MHCIJHAF_03161 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHCIJHAF_03162 3.44e-202 ycgS - - I - - - alpha/beta hydrolase fold
MHCIJHAF_03163 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
MHCIJHAF_03164 2.12e-192 ycgQ - - S ko:K08986 - ko00000 membrane
MHCIJHAF_03165 7.91e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MHCIJHAF_03166 1.05e-315 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCIJHAF_03167 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHCIJHAF_03168 2.1e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MHCIJHAF_03169 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MHCIJHAF_03170 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MHCIJHAF_03171 5.64e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
MHCIJHAF_03172 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
MHCIJHAF_03173 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHCIJHAF_03174 1.31e-140 tmrB - - S - - - AAA domain
MHCIJHAF_03175 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHCIJHAF_03176 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MHCIJHAF_03177 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_03178 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MHCIJHAF_03179 2.61e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
MHCIJHAF_03180 3.04e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCIJHAF_03181 0.0 mdr - - EGP - - - the major facilitator superfamily
MHCIJHAF_03182 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MHCIJHAF_03183 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHCIJHAF_03184 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MHCIJHAF_03185 2.72e-105 ycgB - - - - - - -
MHCIJHAF_03186 0.0 ycgA - - S - - - Membrane
MHCIJHAF_03187 9.75e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MHCIJHAF_03188 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHCIJHAF_03189 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHCIJHAF_03190 3e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MHCIJHAF_03191 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHCIJHAF_03192 3.89e-266 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
MHCIJHAF_03193 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MHCIJHAF_03194 4.21e-245 yceH - - P - - - Belongs to the TelA family
MHCIJHAF_03195 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MHCIJHAF_03196 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MHCIJHAF_03197 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MHCIJHAF_03198 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MHCIJHAF_03199 3.08e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MHCIJHAF_03200 2.63e-241 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHCIJHAF_03201 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHCIJHAF_03202 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHCIJHAF_03203 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHCIJHAF_03204 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHCIJHAF_03205 7.99e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_03206 4.73e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MHCIJHAF_03207 4.23e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MHCIJHAF_03208 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_03209 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_03210 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
MHCIJHAF_03211 5.59e-221 yccK - - C - - - Aldo keto reductase
MHCIJHAF_03212 1.55e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHCIJHAF_03213 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHCIJHAF_03214 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHCIJHAF_03215 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHCIJHAF_03216 6.84e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
MHCIJHAF_03217 4.65e-73 - - - S - - - RDD family
MHCIJHAF_03218 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHCIJHAF_03219 7.18e-259 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MHCIJHAF_03220 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MHCIJHAF_03221 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHCIJHAF_03222 2.22e-257 ycbU - - E - - - Selenocysteine lyase
MHCIJHAF_03223 1.2e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHCIJHAF_03224 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHCIJHAF_03225 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHCIJHAF_03226 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MHCIJHAF_03227 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
MHCIJHAF_03228 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MHCIJHAF_03229 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
MHCIJHAF_03230 4.75e-147 - - - S - - - ABC-2 family transporter protein
MHCIJHAF_03231 2.64e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03232 6.48e-216 ycbM - - T - - - Histidine kinase
MHCIJHAF_03233 3.05e-159 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_03234 4.02e-134 eamA1 - - EG - - - spore germination
MHCIJHAF_03235 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MHCIJHAF_03236 2.37e-220 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MHCIJHAF_03237 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MHCIJHAF_03238 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
MHCIJHAF_03239 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHCIJHAF_03240 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_03241 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHCIJHAF_03242 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
MHCIJHAF_03243 7.01e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MHCIJHAF_03244 1.96e-291 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_03245 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MHCIJHAF_03246 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MHCIJHAF_03247 1.51e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MHCIJHAF_03248 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHCIJHAF_03249 9.43e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHCIJHAF_03251 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MHCIJHAF_03252 2.12e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHCIJHAF_03253 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_03254 4.96e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHCIJHAF_03255 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MHCIJHAF_03256 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
MHCIJHAF_03257 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MHCIJHAF_03258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
MHCIJHAF_03259 5.67e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHCIJHAF_03260 3.91e-214 - - - S - - - Alpha/beta hydrolase family
MHCIJHAF_03262 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
MHCIJHAF_03263 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHCIJHAF_03264 6.07e-187 ybfI - - K - - - AraC-like ligand binding domain
MHCIJHAF_03265 5.27e-208 ybfH - - EG - - - EamA-like transporter family
MHCIJHAF_03266 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MHCIJHAF_03268 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_03269 2.1e-218 ybfA - - K - - - FR47-like protein
MHCIJHAF_03270 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
MHCIJHAF_03271 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MHCIJHAF_03272 5.76e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MHCIJHAF_03273 0.0 ybeC - - E - - - amino acid
MHCIJHAF_03274 1.11e-54 ybyB - - - - - - -
MHCIJHAF_03275 2.67e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MHCIJHAF_03276 5.27e-193 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
MHCIJHAF_03277 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
MHCIJHAF_03278 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MHCIJHAF_03279 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHCIJHAF_03280 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
MHCIJHAF_03281 1.49e-192 ybdN - - - - - - -
MHCIJHAF_03282 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MHCIJHAF_03284 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
MHCIJHAF_03285 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
MHCIJHAF_03286 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHCIJHAF_03287 1.97e-101 - - - CO - - - Thioredoxin-like domain
MHCIJHAF_03288 3.88e-118 - - - C - - - HEAT repeats
MHCIJHAF_03289 3.99e-313 skfF - - S - - - ABC transporter
MHCIJHAF_03290 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHCIJHAF_03291 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MHCIJHAF_03292 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
MHCIJHAF_03294 7.69e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
MHCIJHAF_03295 9.45e-67 - - - K - - - Helix-turn-helix domain
MHCIJHAF_03296 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
MHCIJHAF_03297 4.6e-63 - - - - - - - -
MHCIJHAF_03299 1.34e-118 ybcF - - P - - - carbonic anhydrase
MHCIJHAF_03300 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
MHCIJHAF_03301 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHCIJHAF_03302 3.69e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHCIJHAF_03303 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MHCIJHAF_03304 2.67e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHCIJHAF_03305 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHCIJHAF_03306 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHCIJHAF_03307 1.44e-290 ybbR - - S - - - protein conserved in bacteria
MHCIJHAF_03308 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHCIJHAF_03309 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHCIJHAF_03310 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_03316 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
MHCIJHAF_03317 6.32e-114 ybbJ - - J - - - acetyltransferase
MHCIJHAF_03318 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHCIJHAF_03319 5.43e-194 ybbH - - K - - - transcriptional
MHCIJHAF_03320 5.99e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_03321 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MHCIJHAF_03322 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MHCIJHAF_03323 8.14e-303 ybbC - - S - - - protein conserved in bacteria
MHCIJHAF_03324 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MHCIJHAF_03325 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MHCIJHAF_03326 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_03327 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_03328 3.54e-178 ybbA - - S ko:K07017 - ko00000 Putative esterase
MHCIJHAF_03329 5.36e-203 ybaS - - S - - - Na -dependent transporter
MHCIJHAF_03331 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MHCIJHAF_03332 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_03333 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MHCIJHAF_03334 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MHCIJHAF_03335 1.54e-288 - - - EGP - - - Major Facilitator Superfamily
MHCIJHAF_03336 2.1e-122 - - - S - - - YcxB-like protein
MHCIJHAF_03337 9.36e-205 ycxC - - EG - - - EamA-like transporter family
MHCIJHAF_03338 0.0 ycxD - - K - - - GntR family transcriptional regulator
MHCIJHAF_03339 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MHCIJHAF_03340 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
MHCIJHAF_03341 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHCIJHAF_03342 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHCIJHAF_03343 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHCIJHAF_03344 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MHCIJHAF_03345 1.35e-141 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHCIJHAF_03346 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MHCIJHAF_03347 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MHCIJHAF_03348 1.34e-103 yclD - - - - - - -
MHCIJHAF_03349 8.39e-197 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
MHCIJHAF_03350 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MHCIJHAF_03351 0.0 yclG - - M - - - Pectate lyase superfamily protein
MHCIJHAF_03353 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MHCIJHAF_03354 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
MHCIJHAF_03355 4.24e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MHCIJHAF_03356 4.82e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHCIJHAF_03357 2.59e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MHCIJHAF_03358 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_03359 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHCIJHAF_03360 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MHCIJHAF_03363 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHCIJHAF_03364 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_03365 7.77e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHCIJHAF_03366 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03367 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MHCIJHAF_03368 0.0 ycnB - - EGP - - - the major facilitator superfamily
MHCIJHAF_03369 9.73e-197 ycnC - - K - - - Transcriptional regulator
MHCIJHAF_03370 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MHCIJHAF_03371 1.68e-60 ycnE - - S - - - Monooxygenase
MHCIJHAF_03372 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHCIJHAF_03373 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHCIJHAF_03374 1.89e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHCIJHAF_03375 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHCIJHAF_03376 3.37e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MHCIJHAF_03377 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_03378 3.05e-138 ycnI - - S - - - protein conserved in bacteria
MHCIJHAF_03379 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MHCIJHAF_03380 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHCIJHAF_03381 1.34e-74 - - - - - - - -
MHCIJHAF_03382 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHCIJHAF_03383 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MHCIJHAF_03384 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHCIJHAF_03385 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MHCIJHAF_03387 1.78e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHCIJHAF_03388 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
MHCIJHAF_03389 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MHCIJHAF_03391 1.1e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHCIJHAF_03392 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MHCIJHAF_03393 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHCIJHAF_03394 8.18e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MHCIJHAF_03395 1.19e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MHCIJHAF_03396 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MHCIJHAF_03397 3.12e-170 kipR - - K - - - Transcriptional regulator
MHCIJHAF_03398 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MHCIJHAF_03400 7.67e-66 yczJ - - S - - - biosynthesis
MHCIJHAF_03401 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MHCIJHAF_03402 2.88e-218 ycsN - - S - - - Oxidoreductase
MHCIJHAF_03403 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MHCIJHAF_03404 0.0 ydaB - - IQ - - - acyl-CoA ligase
MHCIJHAF_03405 2.46e-128 ydaC - - Q - - - Methyltransferase domain
MHCIJHAF_03406 8.81e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_03407 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MHCIJHAF_03408 3.67e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHCIJHAF_03409 5.24e-101 ydaG - - S - - - general stress protein
MHCIJHAF_03410 2.18e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHCIJHAF_03411 6.3e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MHCIJHAF_03412 1.61e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MHCIJHAF_03413 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHCIJHAF_03414 5.72e-263 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHCIJHAF_03415 6.07e-191 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MHCIJHAF_03416 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MHCIJHAF_03417 3.2e-303 ydaM - - M - - - Glycosyl transferase family group 2
MHCIJHAF_03418 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MHCIJHAF_03419 0.0 ydaO - - E - - - amino acid
MHCIJHAF_03420 2.28e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MHCIJHAF_03421 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHCIJHAF_03422 2.5e-52 - - - - - - - -
MHCIJHAF_03423 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHCIJHAF_03424 1.67e-42 ydaS - - S - - - membrane
MHCIJHAF_03425 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MHCIJHAF_03426 9.72e-187 ydbA - - P - - - EcsC protein family
MHCIJHAF_03427 4.4e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
MHCIJHAF_03428 3.09e-78 ydbB - - G - - - Cupin domain
MHCIJHAF_03429 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
MHCIJHAF_03430 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
MHCIJHAF_03431 1.49e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHCIJHAF_03432 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHCIJHAF_03433 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MHCIJHAF_03434 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHCIJHAF_03435 1.32e-230 ydbI - - S - - - AI-2E family transporter
MHCIJHAF_03436 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_03437 4.25e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHCIJHAF_03438 9.32e-70 ydbL - - - - - - -
MHCIJHAF_03439 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
MHCIJHAF_03440 1.49e-26 - - - S - - - Fur-regulated basic protein B
MHCIJHAF_03441 2.1e-11 - - - S - - - Fur-regulated basic protein A
MHCIJHAF_03442 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHCIJHAF_03443 4.19e-75 ydbP - - CO - - - Thioredoxin
MHCIJHAF_03444 8.43e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHCIJHAF_03445 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHCIJHAF_03446 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHCIJHAF_03447 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MHCIJHAF_03448 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MHCIJHAF_03449 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MHCIJHAF_03450 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHCIJHAF_03451 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MHCIJHAF_03452 5.92e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHCIJHAF_03453 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHCIJHAF_03454 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHCIJHAF_03455 2.46e-183 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MHCIJHAF_03456 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MHCIJHAF_03457 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHCIJHAF_03458 1.86e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MHCIJHAF_03459 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MHCIJHAF_03460 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHCIJHAF_03461 5.17e-177 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_03462 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MHCIJHAF_03463 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MHCIJHAF_03464 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHCIJHAF_03472 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
MHCIJHAF_03473 2.01e-58 - - - - - - - -
MHCIJHAF_03474 5.86e-38 - - - S - - - LXG domain of WXG superfamily
MHCIJHAF_03475 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
MHCIJHAF_03476 9.05e-56 - - - L - - - HNH nucleases
MHCIJHAF_03479 7.24e-08 - - - S - - - Putative amidase domain
MHCIJHAF_03483 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHCIJHAF_03484 6e-53 - - - - - - - -
MHCIJHAF_03486 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_03487 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCIJHAF_03488 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
MHCIJHAF_03489 2.89e-82 yngL - - S - - - Protein of unknown function (DUF1360)
MHCIJHAF_03490 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MHCIJHAF_03491 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MHCIJHAF_03492 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHCIJHAF_03493 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MHCIJHAF_03494 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MHCIJHAF_03495 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MHCIJHAF_03496 3.49e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MHCIJHAF_03497 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHCIJHAF_03498 1.82e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
MHCIJHAF_03499 2.01e-134 yngC - - S - - - membrane-associated protein
MHCIJHAF_03500 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHCIJHAF_03501 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MHCIJHAF_03502 1.18e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MHCIJHAF_03504 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
MHCIJHAF_03505 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MHCIJHAF_03506 1.06e-75 ynfC - - - - - - -
MHCIJHAF_03507 1.82e-18 - - - - - - - -
MHCIJHAF_03508 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHCIJHAF_03509 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHCIJHAF_03510 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MHCIJHAF_03511 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHCIJHAF_03512 2.57e-64 yneR - - S - - - Belongs to the HesB IscA family
MHCIJHAF_03513 3.72e-68 yneQ - - - - - - -
MHCIJHAF_03514 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MHCIJHAF_03515 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MHCIJHAF_03517 9.26e-10 - - - S - - - Fur-regulated basic protein B
MHCIJHAF_03518 3.07e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHCIJHAF_03519 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHCIJHAF_03520 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MHCIJHAF_03521 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MHCIJHAF_03522 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
MHCIJHAF_03523 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
MHCIJHAF_03524 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MHCIJHAF_03525 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MHCIJHAF_03526 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MHCIJHAF_03527 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
MHCIJHAF_03528 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MHCIJHAF_03529 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MHCIJHAF_03530 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHCIJHAF_03531 1.15e-43 ynzC - - S - - - UPF0291 protein
MHCIJHAF_03532 2.29e-144 yneB - - L - - - resolvase
MHCIJHAF_03533 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHCIJHAF_03534 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHCIJHAF_03535 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHCIJHAF_03536 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
MHCIJHAF_03537 3.26e-175 yndL - - S - - - Replication protein
MHCIJHAF_03539 0.0 yndJ - - S - - - YndJ-like protein
MHCIJHAF_03540 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
MHCIJHAF_03541 5.29e-198 yndG - - S - - - DoxX-like family
MHCIJHAF_03542 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
MHCIJHAF_03543 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
MHCIJHAF_03544 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MHCIJHAF_03547 2.17e-53 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MHCIJHAF_03548 8.92e-96 - - - - - - - -
MHCIJHAF_03549 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
MHCIJHAF_03552 4.12e-96 - - - S - - - Domain of unknown function, YrpD
MHCIJHAF_03553 1.36e-61 - - - S - - - Domain of unknown function, YrpD
MHCIJHAF_03555 3.75e-208 - - - S - - - Thymidylate synthase
MHCIJHAF_03558 7.54e-22 - - - - - - - -
MHCIJHAF_03559 9.28e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MHCIJHAF_03560 6.41e-106 - - - S - - - Protein of unknown function (DUF2691)
MHCIJHAF_03561 3.56e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHCIJHAF_03562 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCIJHAF_03563 1.02e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MHCIJHAF_03564 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MHCIJHAF_03565 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MHCIJHAF_03566 3.02e-276 xylR - - GK - - - ROK family
MHCIJHAF_03567 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MHCIJHAF_03568 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MHCIJHAF_03569 4.15e-108 - - - E - - - phosphoribosylanthranilate isomerase activity
MHCIJHAF_03572 1.39e-145 - - - S - - - Domain of unknown function (DUF3885)
MHCIJHAF_03573 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHCIJHAF_03574 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHCIJHAF_03575 2.28e-93 - - - S - - - CAAX protease self-immunity
MHCIJHAF_03577 7.11e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
MHCIJHAF_03578 6.35e-25 ynaC - - - - - - -
MHCIJHAF_03579 3.26e-113 - - - G - - - SMI1-KNR4 cell-wall
MHCIJHAF_03580 4.15e-49 - - - - - - - -
MHCIJHAF_03582 4.18e-14 - - - - - - - -
MHCIJHAF_03583 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHCIJHAF_03584 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MHCIJHAF_03585 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHCIJHAF_03586 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHCIJHAF_03587 1.09e-88 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MHCIJHAF_03588 5.06e-306 - - - L ko:K06400 - ko00000 Recombinase
MHCIJHAF_03590 2.8e-117 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHCIJHAF_03598 3.18e-204 - - - S - - - Calcineurin-like phosphoesterase
MHCIJHAF_03599 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MHCIJHAF_03601 1.35e-44 - - - - - - - -
MHCIJHAF_03603 5.78e-40 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHCIJHAF_03604 9.21e-209 - - - S - - - Thymidylate synthase
MHCIJHAF_03608 2.36e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MHCIJHAF_03609 2.03e-46 - - - O - - - Glutaredoxin
MHCIJHAF_03610 4.35e-125 - - - L - - - HNH endonuclease
MHCIJHAF_03611 1.44e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCIJHAF_03613 4.66e-208 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCIJHAF_03614 6.63e-266 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCIJHAF_03615 1.56e-86 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MHCIJHAF_03632 1.11e-76 - 2.1.1.37 - L ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MHCIJHAF_03633 2.87e-83 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
MHCIJHAF_03634 3.44e-117 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MHCIJHAF_03635 2.55e-111 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
MHCIJHAF_03640 2.53e-152 - - - S - - - protein conserved in bacteria
MHCIJHAF_03642 1.52e-143 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHCIJHAF_03643 3.93e-65 - - - S - - - DNA primase activity
MHCIJHAF_03644 5.54e-179 - - - L - - - Participates in initiation and elongation during chromosome replication
MHCIJHAF_03649 6.61e-34 - - - S ko:K06327 - ko00000 Inner spore coat protein D
MHCIJHAF_03653 3.57e-205 - - - - - - - -
MHCIJHAF_03654 2.54e-10 - - - S - - - YopX protein
MHCIJHAF_03657 4e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MHCIJHAF_03658 1.3e-174 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
MHCIJHAF_03659 5.68e-85 - - - - - - - -
MHCIJHAF_03661 8.7e-75 - - - - - - - -
MHCIJHAF_03663 2.26e-22 - - - - - - - -
MHCIJHAF_03672 9.94e-14 - - - S - - - Protein of unknown function (DUF2815)
MHCIJHAF_03675 3.51e-140 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
MHCIJHAF_03679 1.85e-54 - - - - - - - -
MHCIJHAF_03683 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_03684 6.81e-225 - - - - - - - -
MHCIJHAF_03685 0.0 - - - S - - - DNA-sulfur modification-associated
MHCIJHAF_03686 9.71e-253 - - - L - - - Belongs to the 'phage' integrase family
MHCIJHAF_03691 1.6e-134 - - - - - - - -
MHCIJHAF_03692 1.32e-41 - - - V - - - HNH endonuclease
MHCIJHAF_03700 6.47e-44 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHCIJHAF_03701 2.1e-102 yoaW - - - - - - -
MHCIJHAF_03702 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHCIJHAF_03703 1.21e-37 - - - S - - - Protein of unknown function (DUF3102)
MHCIJHAF_03709 1.05e-260 - - - - - - - -
MHCIJHAF_03710 8.5e-123 - - - - - - - -
MHCIJHAF_03713 0.0 - - - S - - - RNA-directed RNA polymerase activity
MHCIJHAF_03714 2.41e-07 - - - S - - - nucleic acid binding
MHCIJHAF_03715 2.97e-112 - - - - - - - -
MHCIJHAF_03716 5.8e-48 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHCIJHAF_03717 3.48e-96 - - - - - - - -
MHCIJHAF_03719 9.19e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
MHCIJHAF_03724 1.55e-130 - - - - - - - -
MHCIJHAF_03728 7.34e-86 - - - - - - - -
MHCIJHAF_03731 7.77e-88 - - - - - - - -
MHCIJHAF_03732 1.83e-101 - - - - - - - -
MHCIJHAF_03733 3.62e-114 - - - - - - - -
MHCIJHAF_03734 6.41e-75 - - - - - - - -
MHCIJHAF_03737 4.31e-74 - - - - - - - -
MHCIJHAF_03738 3.16e-222 - - - - - - - -
MHCIJHAF_03741 4.15e-73 - - - - - - - -
MHCIJHAF_03742 3.85e-87 - - - - - - - -
MHCIJHAF_03743 6.75e-245 - - - A - - - Belongs to the 'phage' integrase family
MHCIJHAF_03747 5.66e-159 - - - - - - - -
MHCIJHAF_03748 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHCIJHAF_03749 7.56e-110 - - - S - - - Phage tail protein
MHCIJHAF_03750 0.0 - - - S - - - Pfam Transposase IS66
MHCIJHAF_03751 6.13e-189 - - - - - - - -
MHCIJHAF_03752 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
MHCIJHAF_03753 3.85e-241 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
MHCIJHAF_03755 2.05e-51 - - - S - - - Bacteriophage holin
MHCIJHAF_03756 1.48e-124 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHCIJHAF_03758 4.81e-53 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHCIJHAF_03760 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
MHCIJHAF_03761 2.14e-17 - - - Q - - - methyltransferase
MHCIJHAF_03763 7.18e-298 - - - S - - - damaged DNA binding
MHCIJHAF_03764 2.04e-68 - - - S - - - YolD-like protein
MHCIJHAF_03765 8.09e-53 - - - - - - - -
MHCIJHAF_03767 2.81e-117 yokK - - S - - - SMI1 / KNR4 family
MHCIJHAF_03768 8.76e-99 - - - S - - - SMI1-KNR4 cell-wall
MHCIJHAF_03769 5.39e-216 - - - S - - - Bacterial EndoU nuclease
MHCIJHAF_03770 4.13e-84 - - - G - - - SMI1-KNR4 cell-wall
MHCIJHAF_03771 1.32e-168 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MHCIJHAF_03772 9.2e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
MHCIJHAF_03774 3.46e-123 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MHCIJHAF_03775 2.34e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHCIJHAF_03776 2.24e-141 - - - - - - - -
MHCIJHAF_03777 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCIJHAF_03778 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCIJHAF_03779 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MHCIJHAF_03780 1.2e-30 ymzA - - - - - - -
MHCIJHAF_03781 1.63e-31 - - - - - - - -
MHCIJHAF_03782 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHCIJHAF_03783 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHCIJHAF_03784 5.41e-76 ymaF - - S - - - YmaF family
MHCIJHAF_03786 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MHCIJHAF_03787 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
MHCIJHAF_03788 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MHCIJHAF_03789 3.96e-163 ymaC - - S - - - Replication protein
MHCIJHAF_03791 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MHCIJHAF_03792 1.88e-207 - - - S - - - Metallo-beta-lactamase superfamily
MHCIJHAF_03793 8.03e-81 ymzB - - - - - - -
MHCIJHAF_03794 4.14e-134 pksA - - K - - - Transcriptional regulator
MHCIJHAF_03795 5.38e-125 ymcC - - S - - - Membrane
MHCIJHAF_03796 6.4e-90 - - - S - - - Regulatory protein YrvL
MHCIJHAF_03797 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHCIJHAF_03798 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHCIJHAF_03799 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
MHCIJHAF_03800 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MHCIJHAF_03801 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHCIJHAF_03802 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHCIJHAF_03803 7.59e-250 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MHCIJHAF_03804 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MHCIJHAF_03805 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MHCIJHAF_03806 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHCIJHAF_03807 8.43e-282 pbpX - - V - - - Beta-lactamase
MHCIJHAF_03808 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHCIJHAF_03809 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MHCIJHAF_03810 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHCIJHAF_03811 1.76e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MHCIJHAF_03812 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
MHCIJHAF_03813 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
MHCIJHAF_03814 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHCIJHAF_03815 7.6e-306 ymfH - - S - - - zinc protease
MHCIJHAF_03816 3.17e-297 albE - - S - - - Peptidase M16
MHCIJHAF_03817 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_03818 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_03819 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHCIJHAF_03820 4.94e-44 - - - S - - - YlzJ-like protein
MHCIJHAF_03821 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MHCIJHAF_03822 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHCIJHAF_03823 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHCIJHAF_03824 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHCIJHAF_03825 2.76e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHCIJHAF_03826 3.33e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHCIJHAF_03827 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MHCIJHAF_03828 1.53e-56 ymxH - - S - - - YlmC YmxH family
MHCIJHAF_03829 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
MHCIJHAF_03830 4.33e-234 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MHCIJHAF_03831 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHCIJHAF_03832 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHCIJHAF_03833 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHCIJHAF_03834 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHCIJHAF_03835 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHCIJHAF_03836 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MHCIJHAF_03837 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHCIJHAF_03838 6.16e-63 ylxQ - - J - - - ribosomal protein
MHCIJHAF_03839 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MHCIJHAF_03840 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHCIJHAF_03841 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHCIJHAF_03842 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHCIJHAF_03843 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHCIJHAF_03844 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHCIJHAF_03845 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHCIJHAF_03846 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHCIJHAF_03847 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHCIJHAF_03848 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHCIJHAF_03849 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHCIJHAF_03850 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHCIJHAF_03851 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHCIJHAF_03852 6.62e-99 ylxL - - - - - - -
MHCIJHAF_03853 9.34e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_03854 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHCIJHAF_03855 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHCIJHAF_03856 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MHCIJHAF_03857 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MHCIJHAF_03858 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHCIJHAF_03859 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MHCIJHAF_03860 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MHCIJHAF_03861 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHCIJHAF_03862 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHCIJHAF_03863 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MHCIJHAF_03864 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MHCIJHAF_03865 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MHCIJHAF_03866 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MHCIJHAF_03867 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MHCIJHAF_03868 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHCIJHAF_03869 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHCIJHAF_03870 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MHCIJHAF_03871 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MHCIJHAF_03872 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MHCIJHAF_03873 3.66e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MHCIJHAF_03874 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
MHCIJHAF_03875 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MHCIJHAF_03876 1.17e-305 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHCIJHAF_03877 1.35e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MHCIJHAF_03878 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHCIJHAF_03879 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MHCIJHAF_03880 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MHCIJHAF_03881 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MHCIJHAF_03882 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHCIJHAF_03883 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHCIJHAF_03884 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHCIJHAF_03885 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHCIJHAF_03886 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MHCIJHAF_03887 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHCIJHAF_03888 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHCIJHAF_03889 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MHCIJHAF_03890 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHCIJHAF_03891 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHCIJHAF_03892 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MHCIJHAF_03893 0.0 ylqG - - - - - - -
MHCIJHAF_03894 1.37e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHCIJHAF_03895 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHCIJHAF_03896 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHCIJHAF_03897 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHCIJHAF_03898 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHCIJHAF_03899 1.14e-78 ylqD - - S - - - YlqD protein
MHCIJHAF_03900 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHCIJHAF_03901 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHCIJHAF_03902 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHCIJHAF_03903 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHCIJHAF_03904 1.67e-114 - - - - - - - -
MHCIJHAF_03905 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHCIJHAF_03906 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHCIJHAF_03907 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHCIJHAF_03908 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHCIJHAF_03909 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHCIJHAF_03910 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MHCIJHAF_03911 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHCIJHAF_03912 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHCIJHAF_03913 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHCIJHAF_03914 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MHCIJHAF_03915 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MHCIJHAF_03916 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MHCIJHAF_03917 3.65e-78 yloU - - S - - - protein conserved in bacteria
MHCIJHAF_03918 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHCIJHAF_03919 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHCIJHAF_03920 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHCIJHAF_03921 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHCIJHAF_03922 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHCIJHAF_03923 1.18e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHCIJHAF_03924 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHCIJHAF_03925 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHCIJHAF_03926 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHCIJHAF_03927 2.38e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHCIJHAF_03928 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHCIJHAF_03929 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHCIJHAF_03930 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHCIJHAF_03931 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHCIJHAF_03932 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MHCIJHAF_03933 6.91e-201 yloC - - S - - - stress-induced protein
MHCIJHAF_03934 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MHCIJHAF_03935 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MHCIJHAF_03936 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MHCIJHAF_03937 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MHCIJHAF_03938 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MHCIJHAF_03939 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MHCIJHAF_03940 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MHCIJHAF_03941 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MHCIJHAF_03942 4.19e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MHCIJHAF_03944 5.18e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHCIJHAF_03945 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHCIJHAF_03946 2.2e-223 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHCIJHAF_03947 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHCIJHAF_03948 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MHCIJHAF_03949 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHCIJHAF_03950 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHCIJHAF_03951 3.46e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHCIJHAF_03952 6.15e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MHCIJHAF_03953 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHCIJHAF_03954 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHCIJHAF_03955 6.39e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHCIJHAF_03956 8.21e-71 ylyA - - T - - - COG1734 DnaK suppressor protein
MHCIJHAF_03957 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHCIJHAF_03958 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MHCIJHAF_03959 8.64e-178 ylmH - - S - - - conserved protein, contains S4-like domain
MHCIJHAF_03960 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MHCIJHAF_03961 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHCIJHAF_03962 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHCIJHAF_03963 3.07e-202 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MHCIJHAF_03964 1.46e-50 ylmC - - S - - - sporulation protein
MHCIJHAF_03965 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MHCIJHAF_03966 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHCIJHAF_03967 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_03968 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_03969 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHCIJHAF_03971 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MHCIJHAF_03972 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHCIJHAF_03973 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHCIJHAF_03974 5.37e-76 sbp - - S - - - small basic protein
MHCIJHAF_03975 1.03e-123 ylxX - - S - - - protein conserved in bacteria
MHCIJHAF_03976 4.5e-142 ylxW - - S - - - protein conserved in bacteria
MHCIJHAF_03977 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHCIJHAF_03978 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MHCIJHAF_03979 4.66e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHCIJHAF_03980 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHCIJHAF_03981 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHCIJHAF_03982 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHCIJHAF_03983 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHCIJHAF_03984 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MHCIJHAF_03985 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHCIJHAF_03986 3.42e-68 ftsL - - D - - - Essential cell division protein
MHCIJHAF_03987 2.36e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHCIJHAF_03988 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHCIJHAF_03989 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHCIJHAF_03990 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHCIJHAF_03991 1.33e-115 ylbP - - K - - - n-acetyltransferase
MHCIJHAF_03992 3.87e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHCIJHAF_03993 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MHCIJHAF_03994 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MHCIJHAF_03996 9.84e-300 ylbM - - S - - - Belongs to the UPF0348 family
MHCIJHAF_03997 4.52e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHCIJHAF_03998 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MHCIJHAF_03999 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MHCIJHAF_04000 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHCIJHAF_04001 7.09e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MHCIJHAF_04002 5.1e-51 ylbG - - S - - - UPF0298 protein
MHCIJHAF_04003 4.73e-97 ylbF - - S - - - Belongs to the UPF0342 family
MHCIJHAF_04004 1.73e-48 ylbE - - S - - - YlbE-like protein
MHCIJHAF_04005 3.24e-89 ylbD - - S - - - Putative coat protein
MHCIJHAF_04006 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
MHCIJHAF_04007 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
MHCIJHAF_04008 1.61e-81 ylbA - - S - - - YugN-like family
MHCIJHAF_04009 8.54e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MHCIJHAF_04010 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHCIJHAF_04011 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHCIJHAF_04012 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHCIJHAF_04013 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHCIJHAF_04014 4.88e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHCIJHAF_04015 5.74e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHCIJHAF_04016 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHCIJHAF_04017 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHCIJHAF_04018 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
MHCIJHAF_04019 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MHCIJHAF_04020 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHCIJHAF_04021 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MHCIJHAF_04022 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHCIJHAF_04023 8.92e-44 ylaI - - S - - - protein conserved in bacteria
MHCIJHAF_04024 4.4e-63 ylaH - - S - - - YlaH-like protein
MHCIJHAF_04025 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHCIJHAF_04026 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
MHCIJHAF_04027 9.96e-57 ylaE - - - - - - -
MHCIJHAF_04029 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHCIJHAF_04030 1.44e-56 ylaB - - - - - - -
MHCIJHAF_04031 0.0 ylaA - - - - - - -
MHCIJHAF_04032 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MHCIJHAF_04033 9.64e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MHCIJHAF_04034 2.02e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
MHCIJHAF_04035 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MHCIJHAF_04036 4.48e-35 ykzI - - - - - - -
MHCIJHAF_04037 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
MHCIJHAF_04038 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
MHCIJHAF_04039 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MHCIJHAF_04040 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MHCIJHAF_04041 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHCIJHAF_04042 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHCIJHAF_04043 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHCIJHAF_04044 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHCIJHAF_04045 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
MHCIJHAF_04046 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MHCIJHAF_04047 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHCIJHAF_04048 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
MHCIJHAF_04049 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
MHCIJHAF_04050 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHCIJHAF_04051 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHCIJHAF_04052 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MHCIJHAF_04053 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MHCIJHAF_04054 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHCIJHAF_04055 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MHCIJHAF_04056 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MHCIJHAF_04057 1.09e-18 - - - S - - - Uncharacterized protein YkpC
MHCIJHAF_04058 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHCIJHAF_04059 1.17e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHCIJHAF_04060 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHCIJHAF_04061 4.47e-51 ykoA - - - - - - -
MHCIJHAF_04062 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHCIJHAF_04063 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHCIJHAF_04064 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MHCIJHAF_04065 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_04066 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MHCIJHAF_04067 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_04068 2.34e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHCIJHAF_04069 1.6e-151 yknW - - S - - - Yip1 domain
MHCIJHAF_04070 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHCIJHAF_04071 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHCIJHAF_04072 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHCIJHAF_04073 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MHCIJHAF_04074 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MHCIJHAF_04075 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MHCIJHAF_04076 5.12e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHCIJHAF_04077 4.38e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHCIJHAF_04078 3.45e-200 yknT - - - ko:K06437 - ko00000 -
MHCIJHAF_04079 4.71e-122 rok - - K - - - Repressor of ComK
MHCIJHAF_04080 1.47e-104 ykuV - - CO - - - thiol-disulfide
MHCIJHAF_04081 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
MHCIJHAF_04082 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MHCIJHAF_04083 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
MHCIJHAF_04084 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHCIJHAF_04085 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHCIJHAF_04086 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MHCIJHAF_04087 2.89e-221 ykuO - - - - - - -
MHCIJHAF_04088 2.59e-112 - - - C ko:K03839 - ko00000 Flavodoxin domain
MHCIJHAF_04089 6.52e-216 ccpC - - K - - - Transcriptional regulator
MHCIJHAF_04090 5.15e-100 ykuL - - S - - - CBS domain
MHCIJHAF_04091 7.83e-38 ykzF - - S - - - Antirepressor AbbA
MHCIJHAF_04092 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
MHCIJHAF_04093 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
MHCIJHAF_04094 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
MHCIJHAF_04096 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
MHCIJHAF_04097 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHCIJHAF_04098 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MHCIJHAF_04099 5.84e-115 ykuD - - S - - - protein conserved in bacteria
MHCIJHAF_04100 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHCIJHAF_04101 3.71e-110 ykyB - - S - - - YkyB-like protein
MHCIJHAF_04102 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MHCIJHAF_04103 1.05e-22 - - - - - - - -
MHCIJHAF_04104 1.4e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHCIJHAF_04105 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_04106 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHCIJHAF_04107 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
MHCIJHAF_04108 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHCIJHAF_04109 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHCIJHAF_04110 2.17e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCIJHAF_04111 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MHCIJHAF_04112 6.27e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MHCIJHAF_04113 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHCIJHAF_04114 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MHCIJHAF_04115 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_04116 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MHCIJHAF_04118 1.33e-229 ykvZ - - K - - - Transcriptional regulator
MHCIJHAF_04119 1.58e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MHCIJHAF_04120 3.99e-09 - - - - - - - -
MHCIJHAF_04121 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MHCIJHAF_04122 2.76e-115 stoA - - CO - - - thiol-disulfide
MHCIJHAF_04123 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHCIJHAF_04124 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MHCIJHAF_04125 2.6e-39 - - - - - - - -
MHCIJHAF_04126 5.43e-35 ykvS - - S - - - protein conserved in bacteria
MHCIJHAF_04127 2.2e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
MHCIJHAF_04128 4.3e-205 - - - G - - - Glycosyl hydrolases family 18
MHCIJHAF_04129 1.07e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
MHCIJHAF_04130 4.27e-272 - - - M - - - Glycosyl transferases group 1
MHCIJHAF_04131 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_04132 2.8e-81 ykvN - - K - - - Transcriptional regulator
MHCIJHAF_04133 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHCIJHAF_04134 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHCIJHAF_04135 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MHCIJHAF_04136 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHCIJHAF_04137 4.76e-227 ykvI - - S - - - membrane
MHCIJHAF_04138 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHCIJHAF_04139 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MHCIJHAF_04140 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MHCIJHAF_04141 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MHCIJHAF_04142 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHCIJHAF_04143 5.84e-95 eag - - - - - - -
MHCIJHAF_04145 2.08e-66 - - - S - - - Protein of unknown function (DUF1232)
MHCIJHAF_04146 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MHCIJHAF_04147 1.51e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MHCIJHAF_04148 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MHCIJHAF_04149 5.62e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MHCIJHAF_04150 6.03e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHCIJHAF_04151 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHCIJHAF_04152 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHCIJHAF_04153 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHCIJHAF_04155 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHCIJHAF_04156 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCIJHAF_04157 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHCIJHAF_04158 1.77e-28 ykzE - - - - - - -
MHCIJHAF_04160 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MHCIJHAF_04161 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MHCIJHAF_04162 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
MHCIJHAF_04163 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MHCIJHAF_04164 1.27e-209 rsgI - - S - - - Anti-sigma factor N-terminus
MHCIJHAF_04165 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHCIJHAF_04166 6.3e-225 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHCIJHAF_04167 2.08e-144 ykoX - - S - - - membrane-associated protein
MHCIJHAF_04168 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MHCIJHAF_04169 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHCIJHAF_04170 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MHCIJHAF_04171 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MHCIJHAF_04172 0.0 ykoS - - - - - - -
MHCIJHAF_04173 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MHCIJHAF_04174 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
MHCIJHAF_04175 1.16e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MHCIJHAF_04176 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MHCIJHAF_04177 2.51e-35 ykoL - - - - - - -
MHCIJHAF_04178 3.3e-25 - - - - - - - -
MHCIJHAF_04179 1.49e-70 tnrA - - K - - - transcriptional
MHCIJHAF_04180 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MHCIJHAF_04182 1.45e-08 - - - - - - - -
MHCIJHAF_04183 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MHCIJHAF_04184 4.56e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
MHCIJHAF_04185 3.5e-306 ykoH - - T - - - Histidine kinase
MHCIJHAF_04186 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHCIJHAF_04187 1.21e-142 ykoF - - S - - - YKOF-related Family
MHCIJHAF_04188 1.14e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MHCIJHAF_04189 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCIJHAF_04190 2.2e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MHCIJHAF_04191 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHCIJHAF_04192 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCIJHAF_04193 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHCIJHAF_04194 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
MHCIJHAF_04196 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
MHCIJHAF_04197 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
MHCIJHAF_04198 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
MHCIJHAF_04199 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHCIJHAF_04200 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHCIJHAF_04201 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MHCIJHAF_04202 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MHCIJHAF_04203 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MHCIJHAF_04204 1.46e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHCIJHAF_04205 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
MHCIJHAF_04206 6.55e-166 ykjA - - S - - - Protein of unknown function (DUF421)
MHCIJHAF_04207 3.55e-14 - - - - - - - -
MHCIJHAF_04208 3.1e-288 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHCIJHAF_04209 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
MHCIJHAF_04210 2.53e-205 ykgA - - E - - - Amidinotransferase
MHCIJHAF_04211 1.34e-259 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MHCIJHAF_04212 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_04213 5.97e-209 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHCIJHAF_04214 1.14e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHCIJHAF_04215 8.23e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MHCIJHAF_04217 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHCIJHAF_04218 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCIJHAF_04219 4.28e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_04220 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCIJHAF_04221 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MHCIJHAF_04222 4.06e-179 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
MHCIJHAF_04223 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHCIJHAF_04225 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHCIJHAF_04226 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHCIJHAF_04227 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHCIJHAF_04228 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
MHCIJHAF_04229 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHCIJHAF_04230 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
MHCIJHAF_04231 4.83e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MHCIJHAF_04232 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MHCIJHAF_04233 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MHCIJHAF_04234 8.12e-53 xhlB - - S - - - SPP1 phage holin
MHCIJHAF_04235 2.21e-51 xhlA - - S - - - Haemolysin XhlA
MHCIJHAF_04236 3.28e-193 xepA - - - - - - -
MHCIJHAF_04237 4.47e-31 xkdX - - - - - - -
MHCIJHAF_04238 1.23e-57 xkdW - - S - - - XkdW protein
MHCIJHAF_04239 3.53e-224 - - - - - - - -
MHCIJHAF_04240 4.43e-56 - - - - - - - -
MHCIJHAF_04241 2.27e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MHCIJHAF_04242 6.23e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHCIJHAF_04243 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
MHCIJHAF_04244 6.14e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
MHCIJHAF_04245 2.31e-232 xkdQ - - G - - - NLP P60 protein
MHCIJHAF_04246 3.49e-151 xkdP - - S - - - Lysin motif
MHCIJHAF_04247 0.0 xkdO - - L - - - Transglycosylase SLT domain
MHCIJHAF_04248 3.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MHCIJHAF_04249 6.01e-99 xkdM - - S - - - Phage tail tube protein
MHCIJHAF_04250 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
MHCIJHAF_04251 6.78e-100 xkdJ - - - - - - -
MHCIJHAF_04252 1.13e-112 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHCIJHAF_04253 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
MHCIJHAF_04254 3.16e-80 yqbG - - S - - - Protein of unknown function (DUF3199)
MHCIJHAF_04255 3.91e-217 xkdG - - S - - - Phage capsid family
MHCIJHAF_04256 5.47e-174 xkdF3 - - L - - - Putative phage serine protease XkdF
MHCIJHAF_04257 0.0 yqbA - - S - - - portal protein
MHCIJHAF_04258 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MHCIJHAF_04259 3.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MHCIJHAF_04260 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHCIJHAF_04264 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
MHCIJHAF_04265 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
MHCIJHAF_04267 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
MHCIJHAF_04268 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
MHCIJHAF_04269 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
MHCIJHAF_04270 1.47e-143 yjqB - - S - - - Pfam:DUF867
MHCIJHAF_04271 1.35e-80 yjqA - - S - - - Bacterial PH domain
MHCIJHAF_04272 5.34e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHCIJHAF_04273 1.79e-55 - - - S - - - YCII-related domain
MHCIJHAF_04275 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHCIJHAF_04276 2.48e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
MHCIJHAF_04277 4.68e-104 yjoA - - S - - - DinB family
MHCIJHAF_04278 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MHCIJHAF_04279 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MHCIJHAF_04280 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
MHCIJHAF_04281 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MHCIJHAF_04282 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
MHCIJHAF_04283 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHCIJHAF_04284 1.37e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MHCIJHAF_04285 1.71e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MHCIJHAF_04286 1.71e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
MHCIJHAF_04287 2.5e-313 - - - G ko:K03292 - ko00000 symporter YjmB
MHCIJHAF_04288 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MHCIJHAF_04289 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHCIJHAF_04290 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MHCIJHAF_04291 2.46e-118 yjlB - - S - - - Cupin domain
MHCIJHAF_04292 2.99e-223 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MHCIJHAF_04293 2.3e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHCIJHAF_04294 1.5e-154 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MHCIJHAF_04295 1.01e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MHCIJHAF_04296 1.11e-41 - - - - - - - -
MHCIJHAF_04297 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHCIJHAF_04298 1.58e-284 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHCIJHAF_04300 1.06e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHCIJHAF_04302 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
MHCIJHAF_04303 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MHCIJHAF_04304 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
MHCIJHAF_04305 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
MHCIJHAF_04306 1.12e-210 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MHCIJHAF_04307 1.13e-29 yjfB - - S - - - Putative motility protein
MHCIJHAF_04308 6.11e-106 - - - S - - - Protein of unknown function (DUF2690)
MHCIJHAF_04309 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MHCIJHAF_04311 1.77e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHCIJHAF_04312 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
MHCIJHAF_04313 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
MHCIJHAF_04314 2.38e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHCIJHAF_04316 2.09e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHCIJHAF_04317 3.93e-77 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MHCIJHAF_04318 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHCIJHAF_04319 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCIJHAF_04320 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MHCIJHAF_04321 0.000759 - - - - - - - -
MHCIJHAF_04322 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHCIJHAF_04323 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MHCIJHAF_04324 2.93e-81 yqaS - - L - - - DNA packaging
MHCIJHAF_04326 2.15e-104 - - - L - - - Transposase
MHCIJHAF_04328 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)