ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HMKEOBBI_00001 8.92e-105 - - - M - - - Parallel beta-helix repeats
HMKEOBBI_00003 6.07e-116 - - - K - - - MarR family
HMKEOBBI_00004 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_00005 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HMKEOBBI_00006 1.31e-219 - - - S - - - Patatin-like phospholipase
HMKEOBBI_00007 5.49e-196 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HMKEOBBI_00008 4.94e-214 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HMKEOBBI_00009 4.82e-147 - - - S - - - Vitamin K epoxide reductase
HMKEOBBI_00010 2.09e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
HMKEOBBI_00011 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
HMKEOBBI_00012 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
HMKEOBBI_00013 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMKEOBBI_00014 0.0 - - - S - - - Zincin-like metallopeptidase
HMKEOBBI_00015 2.91e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HMKEOBBI_00016 4.52e-86 - - - S - - - Protein of unknown function (DUF3052)
HMKEOBBI_00017 5.62e-179 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_00018 2.08e-79 - - - S - - - Thiamine-binding protein
HMKEOBBI_00019 1.21e-209 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HMKEOBBI_00020 1.98e-290 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
HMKEOBBI_00021 1.62e-110 - - - - - - - -
HMKEOBBI_00022 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMKEOBBI_00023 3.39e-200 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMKEOBBI_00024 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
HMKEOBBI_00025 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
HMKEOBBI_00026 8.15e-315 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMKEOBBI_00027 3.27e-294 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMKEOBBI_00028 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMKEOBBI_00029 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
HMKEOBBI_00030 1.65e-191 - - - V - - - DivIVA protein
HMKEOBBI_00031 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMKEOBBI_00032 1.89e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMKEOBBI_00034 1.25e-82 - - - - - - - -
HMKEOBBI_00035 3.72e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HMKEOBBI_00036 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMKEOBBI_00037 8.34e-299 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
HMKEOBBI_00038 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
HMKEOBBI_00039 5e-285 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
HMKEOBBI_00040 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMKEOBBI_00041 1.29e-186 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
HMKEOBBI_00043 1.07e-115 - - - - - - - -
HMKEOBBI_00044 9.38e-13 - - - - - - - -
HMKEOBBI_00045 3.79e-16 - - - L - - - PFAM Integrase catalytic
HMKEOBBI_00047 2.84e-313 - - - NU - - - Tfp pilus assembly protein FimV
HMKEOBBI_00048 1.45e-280 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMKEOBBI_00049 1.6e-298 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMKEOBBI_00050 0.0 - - - I - - - acetylesterase activity
HMKEOBBI_00051 1.5e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HMKEOBBI_00052 2.53e-198 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMKEOBBI_00053 1.65e-245 - - - S - - - Domain of unknown function (DUF1963)
HMKEOBBI_00054 1.32e-23 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HMKEOBBI_00055 1.11e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HMKEOBBI_00056 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
HMKEOBBI_00057 1.63e-155 - - - S - - - zinc-ribbon domain
HMKEOBBI_00058 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
HMKEOBBI_00059 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
HMKEOBBI_00060 5e-05 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMKEOBBI_00062 1.24e-258 - - - K - - - WYL domain
HMKEOBBI_00063 5.5e-199 - - - S - - - Aldo/keto reductase family
HMKEOBBI_00064 3.65e-222 dkgV - - C - - - Aldo/keto reductase family
HMKEOBBI_00065 1.19e-97 - - - S - - - Domain of unknown function (DUF4186)
HMKEOBBI_00068 2.91e-214 - - - S - - - Protein conserved in bacteria
HMKEOBBI_00069 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMKEOBBI_00070 1.85e-285 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMKEOBBI_00071 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
HMKEOBBI_00072 1.84e-151 - - - - - - - -
HMKEOBBI_00073 2.24e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMKEOBBI_00074 4.81e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
HMKEOBBI_00075 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
HMKEOBBI_00076 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMKEOBBI_00077 0.0 - - - S - - - Domain of unknown function (DUF5067)
HMKEOBBI_00078 5.77e-35 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator Superfamily
HMKEOBBI_00079 1.2e-241 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HMKEOBBI_00080 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
HMKEOBBI_00081 2.51e-157 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
HMKEOBBI_00082 3.25e-222 - - - - - - - -
HMKEOBBI_00083 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMKEOBBI_00084 1.88e-224 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HMKEOBBI_00085 2.62e-211 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMKEOBBI_00086 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMKEOBBI_00087 3.99e-64 - - - M - - - Lysin motif
HMKEOBBI_00088 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMKEOBBI_00089 5.58e-291 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMKEOBBI_00090 0.0 - - - L - - - DNA helicase
HMKEOBBI_00091 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HMKEOBBI_00092 6.21e-246 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMKEOBBI_00093 1.96e-97 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HMKEOBBI_00094 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
HMKEOBBI_00095 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMKEOBBI_00096 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMKEOBBI_00097 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMKEOBBI_00098 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMKEOBBI_00099 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
HMKEOBBI_00100 3.15e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMKEOBBI_00101 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HMKEOBBI_00102 1.01e-232 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
HMKEOBBI_00105 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMKEOBBI_00106 3.73e-301 - - - G - - - Major Facilitator Superfamily
HMKEOBBI_00107 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HMKEOBBI_00108 2.53e-284 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMKEOBBI_00109 1.98e-168 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HMKEOBBI_00110 2.39e-275 - - - GK - - - ROK family
HMKEOBBI_00111 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMKEOBBI_00112 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HMKEOBBI_00113 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMKEOBBI_00114 3.06e-242 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00115 7.55e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00116 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMKEOBBI_00117 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
HMKEOBBI_00118 7.52e-126 - - - F - - - NUDIX domain
HMKEOBBI_00120 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
HMKEOBBI_00121 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HMKEOBBI_00122 2.31e-174 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HMKEOBBI_00123 6.99e-307 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
HMKEOBBI_00124 3.1e-289 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
HMKEOBBI_00125 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
HMKEOBBI_00126 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMKEOBBI_00127 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMKEOBBI_00128 3.35e-84 - - - - - - - -
HMKEOBBI_00129 7.58e-248 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HMKEOBBI_00130 5.38e-230 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMKEOBBI_00132 6.06e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMKEOBBI_00133 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMKEOBBI_00134 3.41e-172 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
HMKEOBBI_00135 1.4e-10 - - - S - - - Spermine/spermidine synthase domain
HMKEOBBI_00136 2.16e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMKEOBBI_00137 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
HMKEOBBI_00138 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMKEOBBI_00139 9.73e-228 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
HMKEOBBI_00140 1.31e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HMKEOBBI_00141 8.34e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMKEOBBI_00142 6.08e-145 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMKEOBBI_00143 6.03e-191 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
HMKEOBBI_00144 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMKEOBBI_00145 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HMKEOBBI_00146 9.56e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
HMKEOBBI_00147 8.76e-299 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
HMKEOBBI_00148 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
HMKEOBBI_00149 1.83e-109 - - - - - - - -
HMKEOBBI_00150 7.12e-254 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HMKEOBBI_00151 2.1e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
HMKEOBBI_00152 2.67e-56 - - - - - - - -
HMKEOBBI_00153 2.74e-235 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HMKEOBBI_00154 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00155 5.29e-212 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HMKEOBBI_00156 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMKEOBBI_00157 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMKEOBBI_00158 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HMKEOBBI_00159 5.8e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
HMKEOBBI_00160 3.78e-196 - - - S - - - Protein of unknown function (DUF3710)
HMKEOBBI_00161 1.87e-172 - - - S - - - Protein of unknown function (DUF3159)
HMKEOBBI_00162 2.63e-313 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMKEOBBI_00163 4.91e-144 - - - - - - - -
HMKEOBBI_00164 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HMKEOBBI_00165 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMKEOBBI_00167 7.42e-212 - - - S - - - Protein conserved in bacteria
HMKEOBBI_00168 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HMKEOBBI_00169 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMKEOBBI_00170 7.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMKEOBBI_00171 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMKEOBBI_00172 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMKEOBBI_00173 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMKEOBBI_00174 2.25e-178 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
HMKEOBBI_00175 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
HMKEOBBI_00176 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
HMKEOBBI_00177 3.29e-202 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
HMKEOBBI_00178 1.05e-28 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HMKEOBBI_00179 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HMKEOBBI_00180 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
HMKEOBBI_00181 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
HMKEOBBI_00182 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
HMKEOBBI_00183 0.0 - - - S - - - PGAP1-like protein
HMKEOBBI_00185 2.27e-117 - - - - - - - -
HMKEOBBI_00186 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HMKEOBBI_00187 1.86e-245 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HMKEOBBI_00188 3.59e-121 - - - - - - - -
HMKEOBBI_00189 1.13e-225 - - - S - - - Protein of unknown function DUF58
HMKEOBBI_00190 1.22e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HMKEOBBI_00191 2.11e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMKEOBBI_00192 4.24e-105 - - - S - - - LytR cell envelope-related transcriptional attenuator
HMKEOBBI_00193 2.97e-41 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HMKEOBBI_00194 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMKEOBBI_00195 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
HMKEOBBI_00196 6.66e-222 - - - - - - - -
HMKEOBBI_00197 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
HMKEOBBI_00198 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMKEOBBI_00199 7.13e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HMKEOBBI_00200 1.49e-251 - - - S - - - Protein of unknown function (DUF3027)
HMKEOBBI_00201 9.86e-237 uspA - - T - - - Belongs to the universal stress protein A family
HMKEOBBI_00202 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
HMKEOBBI_00206 5.86e-299 - - - S - - - Domain of Unknown Function (DUF349)
HMKEOBBI_00207 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
HMKEOBBI_00208 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMKEOBBI_00209 4.51e-107 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_00210 3.09e-118 - - - S - - - Aminoacyl-tRNA editing domain
HMKEOBBI_00211 9.73e-179 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
HMKEOBBI_00212 1.45e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HMKEOBBI_00213 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00214 6.57e-253 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00215 1.68e-253 - - - S - - - Polyphosphate kinase 2 (PPK2)
HMKEOBBI_00216 0.0 - - - L - - - DEAD DEAH box helicase
HMKEOBBI_00217 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
HMKEOBBI_00218 0.0 - - - EGP - - - Major Facilitator Superfamily
HMKEOBBI_00219 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_00220 1.39e-135 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMKEOBBI_00221 2.21e-178 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMKEOBBI_00222 3.37e-270 - - - E - - - Aminotransferase class I and II
HMKEOBBI_00223 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00224 3.23e-90 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HMKEOBBI_00225 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMKEOBBI_00226 0.0 - - - S - - - Tetratricopeptide repeat
HMKEOBBI_00227 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMKEOBBI_00228 8.24e-270 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HMKEOBBI_00229 2.02e-203 - - - S - - - Protein conserved in bacteria
HMKEOBBI_00233 8.73e-21 - - - - - - - -
HMKEOBBI_00235 1.34e-24 - - - - - - - -
HMKEOBBI_00236 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMKEOBBI_00237 2.47e-181 - - - S - - - Domain of unknown function (DUF4191)
HMKEOBBI_00238 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMKEOBBI_00239 2.94e-134 - - - S - - - Protein of unknown function (DUF3043)
HMKEOBBI_00240 0.0 argE - - E - - - Peptidase dimerisation domain
HMKEOBBI_00241 3.07e-244 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
HMKEOBBI_00242 2.07e-195 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00243 5.63e-253 - - - - - - - -
HMKEOBBI_00244 6.64e-296 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HMKEOBBI_00245 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
HMKEOBBI_00246 5.02e-264 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMKEOBBI_00247 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMKEOBBI_00248 3.3e-281 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
HMKEOBBI_00250 1.82e-165 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMKEOBBI_00251 1.21e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
HMKEOBBI_00252 1.4e-193 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HMKEOBBI_00253 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMKEOBBI_00254 1.45e-123 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HMKEOBBI_00255 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMKEOBBI_00256 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMKEOBBI_00257 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
HMKEOBBI_00258 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
HMKEOBBI_00259 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMKEOBBI_00260 1.03e-131 - - - D - - - Septum formation initiator
HMKEOBBI_00261 3.62e-137 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
HMKEOBBI_00262 2.41e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HMKEOBBI_00264 4.4e-126 - - - - - - - -
HMKEOBBI_00265 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
HMKEOBBI_00266 8.53e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
HMKEOBBI_00267 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMKEOBBI_00268 2.65e-139 - - - - - - - -
HMKEOBBI_00269 5.58e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HMKEOBBI_00270 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMKEOBBI_00271 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HMKEOBBI_00272 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
HMKEOBBI_00273 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
HMKEOBBI_00274 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HMKEOBBI_00275 0.0 - - - S - - - Glycosyl transferase, family 2
HMKEOBBI_00276 0.0 - - - - - - - -
HMKEOBBI_00277 1.05e-85 - - - S - - - Zincin-like metallopeptidase
HMKEOBBI_00278 2.33e-200 - - - T - - - Eukaryotic phosphomannomutase
HMKEOBBI_00279 3.82e-167 pyrE_1 - - S - - - Phosphoribosyl transferase domain
HMKEOBBI_00280 3.2e-93 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
HMKEOBBI_00281 2.06e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMKEOBBI_00282 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
HMKEOBBI_00283 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMKEOBBI_00284 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
HMKEOBBI_00285 3.64e-108 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMKEOBBI_00286 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HMKEOBBI_00287 2.33e-209 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00288 1.55e-232 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HMKEOBBI_00289 1.41e-209 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMKEOBBI_00290 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HMKEOBBI_00291 4.53e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMKEOBBI_00292 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMKEOBBI_00293 1.68e-229 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
HMKEOBBI_00294 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
HMKEOBBI_00295 1.71e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HMKEOBBI_00297 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
HMKEOBBI_00298 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMKEOBBI_00299 5.17e-219 - - - L - - - NIF3 (NGG1p interacting factor 3)
HMKEOBBI_00300 5.78e-162 - - - L - - - NUDIX domain
HMKEOBBI_00301 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HMKEOBBI_00302 8.41e-280 - - - - - - - -
HMKEOBBI_00304 2.57e-67 - - - L - - - Phage integrase family
HMKEOBBI_00305 6.7e-93 - - - L - - - Phage integrase family
HMKEOBBI_00306 1.07e-143 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
HMKEOBBI_00307 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMKEOBBI_00308 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMKEOBBI_00309 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
HMKEOBBI_00310 3.97e-116 - - - S - - - Domain of unknown function (DUF1846)
HMKEOBBI_00311 2.81e-157 - - - - - - - -
HMKEOBBI_00314 3.84e-68 - - - S - - - Protein of unknown function (DUF1294)
HMKEOBBI_00315 7.78e-59 - - - S - - - Protein of unknown function (DUF1294)
HMKEOBBI_00316 1.46e-37 - - - - - - - -
HMKEOBBI_00317 1.76e-18 - - - - - - - -
HMKEOBBI_00318 2.29e-152 - - - S - - - Protein of unknown function (DUF3800)
HMKEOBBI_00319 4.36e-237 - - - S - - - Protein of unknown function DUF262
HMKEOBBI_00321 2.88e-60 - - - L - - - Integrase core domain
HMKEOBBI_00322 5.06e-46 - - - L - - - Transposase
HMKEOBBI_00323 1.48e-232 - - - - - - - -
HMKEOBBI_00324 1.53e-33 - - - - - - - -
HMKEOBBI_00325 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HMKEOBBI_00326 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HMKEOBBI_00327 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
HMKEOBBI_00328 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
HMKEOBBI_00329 2.19e-153 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_00330 2.93e-298 - - - T - - - Histidine kinase
HMKEOBBI_00331 1.06e-57 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
HMKEOBBI_00332 2.22e-231 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00333 6.52e-289 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMKEOBBI_00334 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMKEOBBI_00335 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HMKEOBBI_00336 3.22e-114 - - - L - - - Transposase and inactivated derivatives IS30 family
HMKEOBBI_00338 1.18e-99 - - - - - - - -
HMKEOBBI_00339 1.2e-83 - - - D - - - MobA/MobL family
HMKEOBBI_00340 6.76e-152 tnp3521a2 - - L - - - Integrase core domain
HMKEOBBI_00341 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
HMKEOBBI_00342 9.3e-53 - - - - - - - -
HMKEOBBI_00343 4.2e-145 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
HMKEOBBI_00345 2.02e-141 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMKEOBBI_00346 1.59e-58 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMKEOBBI_00348 1.67e-307 pbuX - - F ko:K03458 - ko00000 Permease family
HMKEOBBI_00349 3.93e-119 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMKEOBBI_00350 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
HMKEOBBI_00351 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMKEOBBI_00352 1e-83 - - - S - - - Domain of unknown function (DUF4418)
HMKEOBBI_00353 9.28e-272 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMKEOBBI_00354 1.29e-170 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_00355 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMKEOBBI_00356 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
HMKEOBBI_00357 5.11e-172 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HMKEOBBI_00358 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
HMKEOBBI_00359 7.33e-50 - - - - - - - -
HMKEOBBI_00360 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMKEOBBI_00361 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMKEOBBI_00362 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMKEOBBI_00363 4.35e-68 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
HMKEOBBI_00364 4.5e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMKEOBBI_00365 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMKEOBBI_00366 1.6e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HMKEOBBI_00367 4.78e-138 - - - - - - - -
HMKEOBBI_00368 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_00369 1.76e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
HMKEOBBI_00370 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMKEOBBI_00371 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
HMKEOBBI_00372 2.92e-298 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
HMKEOBBI_00373 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HMKEOBBI_00374 3.62e-306 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMKEOBBI_00375 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HMKEOBBI_00376 2.56e-141 - - - S - - - Iron-sulfur cluster assembly protein
HMKEOBBI_00377 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMKEOBBI_00378 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
HMKEOBBI_00380 2.18e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMKEOBBI_00381 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HMKEOBBI_00382 1.49e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
HMKEOBBI_00383 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMKEOBBI_00384 0.0 corC - - S - - - CBS domain
HMKEOBBI_00385 1.45e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMKEOBBI_00386 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HMKEOBBI_00387 5.66e-258 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
HMKEOBBI_00388 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
HMKEOBBI_00389 3.47e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HMKEOBBI_00390 4.21e-242 - - - S ko:K06889 - ko00000 alpha beta
HMKEOBBI_00391 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMKEOBBI_00392 1.11e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
HMKEOBBI_00394 3.19e-58 - - - T - - - RNA ligase
HMKEOBBI_00395 2.68e-174 - - - S - - - UPF0126 domain
HMKEOBBI_00396 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HMKEOBBI_00397 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMKEOBBI_00398 3.85e-311 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HMKEOBBI_00399 9.79e-18 - - - S ko:K07149 - ko00000 Membrane
HMKEOBBI_00400 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
HMKEOBBI_00401 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
HMKEOBBI_00402 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
HMKEOBBI_00403 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMKEOBBI_00404 5.23e-107 - - - - - - - -
HMKEOBBI_00405 5.58e-311 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
HMKEOBBI_00406 4.56e-209 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00407 2.18e-203 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
HMKEOBBI_00408 4.78e-143 - - - S ko:K07126 - ko00000 Sel1-like repeats.
HMKEOBBI_00409 1.11e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMKEOBBI_00410 7.87e-51 - - - L - - - Helix-turn-helix domain
HMKEOBBI_00411 7.3e-234 - - - L ko:K07485 - ko00000 Transposase
HMKEOBBI_00412 1.09e-168 - - - - - - - -
HMKEOBBI_00413 0.0 - - - KL - - - Type III restriction enzyme res subunit
HMKEOBBI_00414 3.18e-49 - - - L - - - Eco57I restriction-modification methylase
HMKEOBBI_00415 3.01e-71 - - - L - - - Eco57I restriction-modification methylase
HMKEOBBI_00416 6.12e-233 - - - V - - - Type III restriction enzyme res subunit
HMKEOBBI_00417 2.77e-65 - - - S - - - SIR2-like domain
HMKEOBBI_00418 2e-316 - - - S ko:K06915 - ko00000 AAA-like domain
HMKEOBBI_00419 0.0 - - - S - - - Protein of unknown function DUF262
HMKEOBBI_00420 7.96e-41 - - - - - - - -
HMKEOBBI_00421 3.16e-118 - - - E - - - Rard protein
HMKEOBBI_00422 1.17e-34 - - - S - - - Rard protein
HMKEOBBI_00423 3.14e-225 - - - I - - - alpha/beta hydrolase fold
HMKEOBBI_00424 2e-265 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HMKEOBBI_00425 1.67e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
HMKEOBBI_00426 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMKEOBBI_00427 8.19e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HMKEOBBI_00429 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HMKEOBBI_00430 2.71e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HMKEOBBI_00431 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HMKEOBBI_00432 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMKEOBBI_00433 3.99e-231 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
HMKEOBBI_00434 3.07e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HMKEOBBI_00435 1.01e-229 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMKEOBBI_00436 5.01e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMKEOBBI_00437 9.04e-34 - - - K - - - MerR family regulatory protein
HMKEOBBI_00438 1.09e-248 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HMKEOBBI_00439 6.71e-207 - - - - - - - -
HMKEOBBI_00440 1.76e-19 - - - KLT - - - Protein tyrosine kinase
HMKEOBBI_00441 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMKEOBBI_00442 8.03e-311 - - - V - - - MatE
HMKEOBBI_00443 6.88e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
HMKEOBBI_00444 2.69e-172 - - - L ko:K07457 - ko00000 endonuclease III
HMKEOBBI_00445 2.51e-120 - - - K - - - Transcriptional regulator PadR-like family
HMKEOBBI_00446 3.24e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
HMKEOBBI_00447 2.58e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
HMKEOBBI_00448 3.44e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
HMKEOBBI_00449 1.17e-54 - - - K - - - Helix-turn-helix
HMKEOBBI_00450 6.69e-61 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
HMKEOBBI_00451 9.14e-25 - - - - - - - -
HMKEOBBI_00452 1.59e-129 - - - K - - - Bacterial regulatory proteins, tetR family
HMKEOBBI_00453 7.13e-35 - - - T - - - Domain of unknown function (DUF4234)
HMKEOBBI_00454 7.12e-75 - - - T - - - Domain of unknown function (DUF4234)
HMKEOBBI_00455 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HMKEOBBI_00456 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMKEOBBI_00457 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMKEOBBI_00458 4.33e-185 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HMKEOBBI_00459 5.71e-78 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
HMKEOBBI_00461 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HMKEOBBI_00462 0.0 - - - K - - - WYL domain
HMKEOBBI_00463 1.29e-70 - - - - - - - -
HMKEOBBI_00464 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
HMKEOBBI_00465 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HMKEOBBI_00466 5.93e-183 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
HMKEOBBI_00469 3.01e-117 - - - K - - - Putative zinc ribbon domain
HMKEOBBI_00470 4.36e-162 - - - S - - - GyrI-like small molecule binding domain
HMKEOBBI_00471 4.2e-31 - - - L - - - DNA integration
HMKEOBBI_00473 2.84e-82 - - - - - - - -
HMKEOBBI_00474 5.64e-153 merR2 - - K - - - helix_turn_helix, mercury resistance
HMKEOBBI_00475 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HMKEOBBI_00476 2.65e-180 - - - S - - - Bacterial protein of unknown function (DUF881)
HMKEOBBI_00477 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
HMKEOBBI_00478 5.59e-223 - - - S - - - Bacterial protein of unknown function (DUF881)
HMKEOBBI_00479 1.06e-149 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMKEOBBI_00480 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
HMKEOBBI_00481 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
HMKEOBBI_00482 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
HMKEOBBI_00483 2.07e-237 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMKEOBBI_00484 1.07e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMKEOBBI_00485 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMKEOBBI_00486 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HMKEOBBI_00487 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HMKEOBBI_00488 2.83e-166 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMKEOBBI_00489 5.17e-56 - - - - - - - -
HMKEOBBI_00490 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HMKEOBBI_00491 1.1e-313 - - - - - - - -
HMKEOBBI_00492 9.52e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMKEOBBI_00493 8.17e-285 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMKEOBBI_00494 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMKEOBBI_00495 5.39e-65 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
HMKEOBBI_00496 8.06e-258 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMKEOBBI_00497 3.69e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMKEOBBI_00499 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HMKEOBBI_00500 2.79e-176 yebC - - K - - - transcriptional regulatory protein
HMKEOBBI_00501 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HMKEOBBI_00502 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMKEOBBI_00503 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMKEOBBI_00506 0.0 - - - - - - - -
HMKEOBBI_00510 2.89e-199 - - - S - - - PAC2 family
HMKEOBBI_00511 8.18e-216 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMKEOBBI_00512 8.17e-204 - - - G - - - Fructosamine kinase
HMKEOBBI_00513 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMKEOBBI_00514 1.54e-274 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMKEOBBI_00515 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
HMKEOBBI_00516 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMKEOBBI_00517 3.12e-182 - - - S - - - Protein of unknown function (DUF1275)
HMKEOBBI_00518 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMKEOBBI_00520 1.49e-308 - - - V - - - MatE
HMKEOBBI_00521 2.44e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMKEOBBI_00522 1.18e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HMKEOBBI_00523 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HMKEOBBI_00524 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMKEOBBI_00525 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
HMKEOBBI_00526 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HMKEOBBI_00527 3.02e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HMKEOBBI_00528 2.6e-231 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
HMKEOBBI_00529 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMKEOBBI_00530 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMKEOBBI_00531 2.59e-110 - - - - - - - -
HMKEOBBI_00532 3.65e-08 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HMKEOBBI_00533 8.67e-151 - - - K - - - Transcriptional regulatory protein, C terminal
HMKEOBBI_00534 1.34e-275 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMKEOBBI_00535 6.89e-180 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HMKEOBBI_00536 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
HMKEOBBI_00537 8.31e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HMKEOBBI_00538 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HMKEOBBI_00539 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
HMKEOBBI_00540 3.68e-277 - - - GK - - - ROK family
HMKEOBBI_00541 1.69e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMKEOBBI_00542 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HMKEOBBI_00543 5.52e-215 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HMKEOBBI_00544 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00545 6.09e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMKEOBBI_00546 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMKEOBBI_00547 4.17e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMKEOBBI_00548 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMKEOBBI_00549 1.48e-289 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMKEOBBI_00550 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
HMKEOBBI_00551 6.26e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMKEOBBI_00552 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HMKEOBBI_00553 3.84e-165 - - - S - - - alpha beta
HMKEOBBI_00554 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMKEOBBI_00555 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HMKEOBBI_00556 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMKEOBBI_00557 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
HMKEOBBI_00558 3.59e-118 - - - - - - - -
HMKEOBBI_00559 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
HMKEOBBI_00560 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
HMKEOBBI_00561 0.0 - - - G - - - ABC transporter substrate-binding protein
HMKEOBBI_00562 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HMKEOBBI_00563 2.46e-167 - - - M - - - Peptidase family M23
HMKEOBBI_00565 1.61e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMKEOBBI_00566 7.03e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
HMKEOBBI_00567 2.83e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
HMKEOBBI_00568 3.13e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
HMKEOBBI_00569 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HMKEOBBI_00570 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
HMKEOBBI_00571 2.02e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
HMKEOBBI_00572 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HMKEOBBI_00573 7.56e-214 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HMKEOBBI_00574 2.45e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HMKEOBBI_00575 1.72e-208 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HMKEOBBI_00576 0.0 - - - E - - - Serine carboxypeptidase
HMKEOBBI_00577 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_00578 9.92e-184 - - - S - - - Domain of unknown function (DUF4194)
HMKEOBBI_00579 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_00580 9.92e-206 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMKEOBBI_00581 9.61e-84 - - - K - - - Protein of unknown function, DUF488
HMKEOBBI_00582 1.3e-161 - - - J - - - Acetyltransferase (GNAT) domain
HMKEOBBI_00583 2.67e-117 - - - K - - - FR47-like protein
HMKEOBBI_00584 6.31e-42 - - - K - - - Transcriptional regulator
HMKEOBBI_00585 3.14e-117 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
HMKEOBBI_00587 4.88e-236 - - - S - - - Acetyltransferase (GNAT) domain
HMKEOBBI_00588 4.77e-97 qseC 2.7.13.3 - T ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Histidine kinase
HMKEOBBI_00589 1.4e-170 - - - S - - - SOS response associated peptidase (SRAP)
HMKEOBBI_00590 1.72e-52 - - - - - - - -
HMKEOBBI_00592 1.31e-103 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMKEOBBI_00593 9.32e-225 - - - M - - - heme binding
HMKEOBBI_00594 3.19e-38 - - - EGP ko:K03446,ko:K03466,ko:K03762,ko:K08217 - br01600,ko00000,ko00002,ko01504,ko02000,ko03036 Major facilitator Superfamily
HMKEOBBI_00595 3.33e-128 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HMKEOBBI_00597 5.09e-203 - - - - - - - -
HMKEOBBI_00598 2.67e-124 - - - S - - - Putative ABC-transporter type IV
HMKEOBBI_00599 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HMKEOBBI_00600 5.57e-247 - - - V - - - VanZ like family
HMKEOBBI_00601 1.06e-67 - - - KT - - - RESPONSE REGULATOR receiver
HMKEOBBI_00602 3.34e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
HMKEOBBI_00603 6.22e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
HMKEOBBI_00604 2.32e-169 - - - C - - - Putative TM nitroreductase
HMKEOBBI_00605 1.58e-158 - - - - - - - -
HMKEOBBI_00607 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
HMKEOBBI_00608 2.55e-100 - - - S - - - Bacterial PH domain
HMKEOBBI_00609 1.92e-176 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HMKEOBBI_00610 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMKEOBBI_00611 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMKEOBBI_00613 2.54e-243 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMKEOBBI_00614 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMKEOBBI_00615 4.42e-121 - - - - - - - -
HMKEOBBI_00616 2.93e-299 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMKEOBBI_00617 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
HMKEOBBI_00618 3.24e-158 - - - S - - - ABC-2 family transporter protein
HMKEOBBI_00619 6.5e-163 - - - S - - - ABC-2 family transporter protein
HMKEOBBI_00620 2.47e-224 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00621 2.84e-77 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HMKEOBBI_00622 1.24e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
HMKEOBBI_00623 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HMKEOBBI_00624 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMKEOBBI_00625 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
HMKEOBBI_00626 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
HMKEOBBI_00627 1.03e-139 - - - - - - - -
HMKEOBBI_00628 9.34e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HMKEOBBI_00630 1.53e-242 - - - G - - - Haloacid dehalogenase-like hydrolase
HMKEOBBI_00631 1.36e-267 - - - L - - - Tetratricopeptide repeat
HMKEOBBI_00632 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMKEOBBI_00633 3.54e-185 - - - S - - - Putative ABC-transporter type IV
HMKEOBBI_00634 9.62e-142 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMKEOBBI_00635 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HMKEOBBI_00636 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HMKEOBBI_00637 0.0 - - - K - - - Putative DNA-binding domain
HMKEOBBI_00638 4.67e-30 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HMKEOBBI_00639 2e-41 - - - - - - - -
HMKEOBBI_00640 2.59e-198 - - - S - - - Domain of unknown function (DUF4357)
HMKEOBBI_00641 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
HMKEOBBI_00642 1.03e-145 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
HMKEOBBI_00643 8.68e-229 - - - L - - - Phage integrase family
HMKEOBBI_00644 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMKEOBBI_00645 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HMKEOBBI_00646 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMKEOBBI_00647 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HMKEOBBI_00648 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HMKEOBBI_00649 1.82e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMKEOBBI_00650 4.51e-261 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMKEOBBI_00651 1.23e-133 - - - - - - - -
HMKEOBBI_00652 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
HMKEOBBI_00653 4.32e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMKEOBBI_00654 4.53e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMKEOBBI_00655 9.68e-173 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00656 9.25e-176 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HMKEOBBI_00657 7.28e-71 - - - IQ - - - oxidoreductase activity
HMKEOBBI_00659 1.84e-98 - - - K - - - AraC-like ligand binding domain
HMKEOBBI_00660 2.75e-304 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
HMKEOBBI_00661 1.72e-204 - - - G - - - Phosphoglycerate mutase family
HMKEOBBI_00662 4.33e-238 - - - S - - - Conserved hypothetical protein 698
HMKEOBBI_00663 8.63e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HMKEOBBI_00664 5.28e-152 - - - E - - - haloacid dehalogenase-like hydrolase
HMKEOBBI_00665 0.0 - - - M - - - Glycosyltransferase like family 2
HMKEOBBI_00667 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HMKEOBBI_00668 2.14e-160 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HMKEOBBI_00669 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMKEOBBI_00670 5.64e-67 - - - - - - - -
HMKEOBBI_00671 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HMKEOBBI_00672 7.03e-86 - - - S - - - Zincin-like metallopeptidase
HMKEOBBI_00673 1.1e-112 - - - S - - - Helix-turn-helix
HMKEOBBI_00674 1.14e-261 - - - S - - - Short C-terminal domain
HMKEOBBI_00675 1.1e-30 - - - - - - - -
HMKEOBBI_00677 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
HMKEOBBI_00678 0.0 - - - KLT - - - Protein tyrosine kinase
HMKEOBBI_00679 6.29e-103 - - - S - - - Cupin 2, conserved barrel domain protein
HMKEOBBI_00680 3.83e-202 - - - J - - - Methyltransferase domain
HMKEOBBI_00681 5.59e-78 yccF - - S - - - Inner membrane component domain
HMKEOBBI_00682 2.73e-162 - - - E - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_00683 8.04e-313 - - - K - - - Fic/DOC family
HMKEOBBI_00684 5.2e-63 - - - - - - - -
HMKEOBBI_00687 1.3e-10 rep 3.6.4.12 - L ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
HMKEOBBI_00688 1.34e-75 - - - J - - - tRNA cytidylyltransferase activity
HMKEOBBI_00689 3.42e-298 - 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme res subunit
HMKEOBBI_00690 3.61e-243 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase
HMKEOBBI_00691 1.44e-71 - 2.1.1.113, 2.1.1.72 - L ko:K00571,ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HMKEOBBI_00692 1.02e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMKEOBBI_00693 1.27e-292 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HMKEOBBI_00694 9.77e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00695 2.72e-261 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMKEOBBI_00696 1.1e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HMKEOBBI_00697 3.45e-240 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HMKEOBBI_00698 1.28e-187 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
HMKEOBBI_00699 2.32e-210 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
HMKEOBBI_00700 1.74e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMKEOBBI_00701 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
HMKEOBBI_00702 0.0 - - - T - - - Histidine kinase
HMKEOBBI_00703 4.15e-171 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_00704 0.0 - - - I - - - PAP2 superfamily
HMKEOBBI_00705 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HMKEOBBI_00706 2.96e-210 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_00707 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
HMKEOBBI_00708 2.83e-201 - - - S - - - Putative ABC-transporter type IV
HMKEOBBI_00709 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HMKEOBBI_00710 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
HMKEOBBI_00711 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
HMKEOBBI_00712 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
HMKEOBBI_00713 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
HMKEOBBI_00714 3.57e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HMKEOBBI_00715 1.01e-150 safC - - S - - - O-methyltransferase
HMKEOBBI_00716 7.06e-221 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HMKEOBBI_00717 1.67e-290 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HMKEOBBI_00718 4.28e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
HMKEOBBI_00721 1.23e-311 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMKEOBBI_00722 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMKEOBBI_00723 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMKEOBBI_00724 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HMKEOBBI_00725 5.17e-307 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMKEOBBI_00726 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
HMKEOBBI_00727 1.94e-146 - - - S - - - Protein of unknown function (DUF3000)
HMKEOBBI_00728 3.65e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMKEOBBI_00729 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HMKEOBBI_00730 3.51e-52 - - - - - - - -
HMKEOBBI_00731 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMKEOBBI_00732 2e-285 - - - S - - - Peptidase dimerisation domain
HMKEOBBI_00733 1.73e-107 - - - P - - - ABC-type metal ion transport system permease component
HMKEOBBI_00734 2.76e-212 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMKEOBBI_00735 3.42e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMKEOBBI_00736 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HMKEOBBI_00737 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
HMKEOBBI_00738 9.23e-266 - - - E - - - Belongs to the peptidase S1B family
HMKEOBBI_00740 2.33e-39 - - - - - - - -
HMKEOBBI_00741 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMKEOBBI_00742 5.02e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMKEOBBI_00743 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
HMKEOBBI_00744 7.18e-236 - - - S - - - Protein of unknown function (DUF3071)
HMKEOBBI_00745 3.3e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
HMKEOBBI_00746 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HMKEOBBI_00747 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HMKEOBBI_00748 1.65e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HMKEOBBI_00749 2.83e-22 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HMKEOBBI_00750 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HMKEOBBI_00751 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HMKEOBBI_00752 3.09e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMKEOBBI_00753 1.98e-157 - - - - - - - -
HMKEOBBI_00754 2.13e-255 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMKEOBBI_00755 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
HMKEOBBI_00756 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HMKEOBBI_00757 3.08e-140 - - - - - - - -
HMKEOBBI_00758 1.86e-245 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMKEOBBI_00759 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMKEOBBI_00760 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMKEOBBI_00762 1.39e-95 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HMKEOBBI_00763 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMKEOBBI_00764 1.96e-53 - - - S - - - Protein of unknown function (DUF3046)
HMKEOBBI_00765 2.53e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
HMKEOBBI_00766 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HMKEOBBI_00767 6.37e-160 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMKEOBBI_00768 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
HMKEOBBI_00769 3.82e-176 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HMKEOBBI_00770 2.09e-234 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMKEOBBI_00771 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMKEOBBI_00772 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
HMKEOBBI_00773 1.83e-217 - - - EG - - - EamA-like transporter family
HMKEOBBI_00774 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
HMKEOBBI_00775 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
HMKEOBBI_00776 0.0 - - - T - - - Histidine kinase
HMKEOBBI_00777 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_00778 0.0 - - - S - - - Protein of unknown function DUF262
HMKEOBBI_00779 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HMKEOBBI_00780 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HMKEOBBI_00781 9.86e-304 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HMKEOBBI_00782 2.04e-150 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMKEOBBI_00783 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMKEOBBI_00785 1.68e-251 - - - EGP - - - Transmembrane secretion effector
HMKEOBBI_00786 0.0 - - - S - - - Esterase-like activity of phytase
HMKEOBBI_00787 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMKEOBBI_00788 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMKEOBBI_00789 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMKEOBBI_00790 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMKEOBBI_00792 5.42e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
HMKEOBBI_00793 4.41e-291 - - - M - - - Glycosyl transferase 4-like domain
HMKEOBBI_00794 0.0 - - - M - - - Parallel beta-helix repeats
HMKEOBBI_00795 1.91e-298 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMKEOBBI_00796 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HMKEOBBI_00797 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
HMKEOBBI_00798 5.92e-142 - - - - - - - -
HMKEOBBI_00799 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
HMKEOBBI_00800 3.14e-188 nnrE - - L - - - Uracil DNA glycosylase superfamily
HMKEOBBI_00801 4.51e-44 - - - K - - - DNA-binding transcription factor activity
HMKEOBBI_00802 1.64e-90 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMKEOBBI_00803 9.82e-45 - - - - - - - -
HMKEOBBI_00804 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
HMKEOBBI_00805 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMKEOBBI_00806 1.21e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HMKEOBBI_00807 5.35e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HMKEOBBI_00808 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
HMKEOBBI_00809 0.0 - - - S - - - Putative esterase
HMKEOBBI_00810 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
HMKEOBBI_00812 5.31e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HMKEOBBI_00813 1.82e-178 - - - S - - - cobalamin synthesis protein
HMKEOBBI_00814 4.39e-62 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HMKEOBBI_00815 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMKEOBBI_00816 1.79e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HMKEOBBI_00817 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
HMKEOBBI_00818 6.34e-33 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
HMKEOBBI_00819 2.92e-257 - - - S ko:K07089 - ko00000 Predicted permease
HMKEOBBI_00820 1.7e-84 - - - S - - - TIGRFAM TIGR03943 family protein
HMKEOBBI_00821 9.36e-66 - - - S - - - TIGRFAM TIGR03943 family protein
HMKEOBBI_00822 5.38e-61 - - - - - - - -
HMKEOBBI_00823 8.27e-96 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HMKEOBBI_00824 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMKEOBBI_00825 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMKEOBBI_00826 5.85e-228 yogA - - C - - - Zinc-binding dehydrogenase
HMKEOBBI_00827 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMKEOBBI_00829 2.12e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
HMKEOBBI_00830 2.99e-289 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HMKEOBBI_00831 3.19e-205 - - - K - - - Helix-turn-helix domain, rpiR family
HMKEOBBI_00832 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMKEOBBI_00833 1.45e-312 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
HMKEOBBI_00834 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMKEOBBI_00835 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
HMKEOBBI_00836 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMKEOBBI_00837 4.1e-39 - - - J - - - Acetyltransferase (GNAT) domain
HMKEOBBI_00838 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMKEOBBI_00839 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HMKEOBBI_00840 4.33e-281 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMKEOBBI_00841 1.83e-244 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HMKEOBBI_00842 2.07e-141 - - - - - - - -
HMKEOBBI_00844 1.95e-128 - - - - - - - -
HMKEOBBI_00845 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
HMKEOBBI_00846 1.62e-204 tnp3521a2 - - L - - - Integrase core domain
HMKEOBBI_00847 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HMKEOBBI_00848 2.66e-76 yccF - - S - - - Inner membrane component domain
HMKEOBBI_00849 1.9e-17 - - - - - - - -
HMKEOBBI_00850 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HMKEOBBI_00851 7.04e-57 - - - L - - - Integrase core domain
HMKEOBBI_00852 2.24e-58 istB - - L - - - IstB-like ATP binding protein
HMKEOBBI_00853 1.48e-58 - - - L ko:K07485 - ko00000 Transposase
HMKEOBBI_00854 1.55e-42 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_00855 5.53e-96 - - - I - - - Sterol carrier protein
HMKEOBBI_00856 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMKEOBBI_00857 7.68e-47 - - - - - - - -
HMKEOBBI_00858 2.4e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HMKEOBBI_00859 8.87e-118 - - - L - - - HTH-like domain
HMKEOBBI_00860 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
HMKEOBBI_00861 8.05e-100 crgA - - D - - - Involved in cell division
HMKEOBBI_00862 1.18e-182 - - - S - - - Bacterial protein of unknown function (DUF881)
HMKEOBBI_00863 1.14e-295 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HMKEOBBI_00864 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
HMKEOBBI_00865 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HMKEOBBI_00866 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HMKEOBBI_00867 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HMKEOBBI_00868 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HMKEOBBI_00869 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
HMKEOBBI_00870 2.04e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HMKEOBBI_00871 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
HMKEOBBI_00872 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
HMKEOBBI_00873 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HMKEOBBI_00874 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HMKEOBBI_00875 7.23e-265 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
HMKEOBBI_00876 1.94e-216 - - - EG - - - EamA-like transporter family
HMKEOBBI_00877 1.92e-146 - - - - - - - -
HMKEOBBI_00879 4.1e-251 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMKEOBBI_00881 0.0 - - - KL - - - Domain of unknown function (DUF3427)
HMKEOBBI_00882 3.85e-115 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HMKEOBBI_00883 3.91e-61 - - - D - - - DivIVA domain protein
HMKEOBBI_00884 3.02e-70 - - - S - - - Putative heavy-metal-binding
HMKEOBBI_00885 6.18e-199 - - - I - - - Serine aminopeptidase, S33
HMKEOBBI_00886 4.51e-110 - - - Q - - - Acetyltransferase (GNAT) domain
HMKEOBBI_00888 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMKEOBBI_00889 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
HMKEOBBI_00890 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HMKEOBBI_00891 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HMKEOBBI_00892 2.44e-216 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HMKEOBBI_00894 1.63e-63 - - - S - - - Protein of unknown function DUF262
HMKEOBBI_00895 7.01e-98 - - - S - - - Protein of unknown function DUF262
HMKEOBBI_00896 2.08e-247 - - - - - - - -
HMKEOBBI_00897 9.59e-104 - - - S - - - Nucleotidyltransferase domain
HMKEOBBI_00898 6.31e-90 - - - K - - - FR47-like protein
HMKEOBBI_00899 1.03e-53 - - - S - - - Polyketide cyclase / dehydrase and lipid transport
HMKEOBBI_00900 7.68e-104 - - - S - - - GyrI-like small molecule binding domain
HMKEOBBI_00901 4.53e-45 - - - S - - - Bacterial mobilisation protein (MobC)
HMKEOBBI_00902 3.57e-302 - - - U - - - Relaxase/Mobilisation nuclease domain
HMKEOBBI_00904 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HMKEOBBI_00905 1.25e-252 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HMKEOBBI_00906 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMKEOBBI_00907 1.02e-209 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMKEOBBI_00908 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMKEOBBI_00909 1.81e-252 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_00910 5.41e-100 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
HMKEOBBI_00911 0.0 scrT - - G - - - Transporter major facilitator family protein
HMKEOBBI_00912 0.0 - - - EGP - - - Sugar (and other) transporter
HMKEOBBI_00913 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMKEOBBI_00914 1.76e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMKEOBBI_00915 3.84e-233 - - - S - - - Protein of unknown function (DUF559)
HMKEOBBI_00917 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_00918 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
HMKEOBBI_00919 7.06e-132 - - - K - - - Transcriptional regulator C-terminal region
HMKEOBBI_00920 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_00921 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMKEOBBI_00922 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMKEOBBI_00923 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMKEOBBI_00924 2.48e-48 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMKEOBBI_00925 1.38e-127 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
HMKEOBBI_00926 2.61e-198 - - - S ko:K07058 - ko00000 Virulence factor BrkB
HMKEOBBI_00927 7.13e-56 - - - O - - - Glutaredoxin
HMKEOBBI_00928 8.41e-106 - - - L ko:K07485 - ko00000 Transposase
HMKEOBBI_00930 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HMKEOBBI_00931 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_00932 1.29e-191 - - - L ko:K07454 - ko00000 HNH endonuclease
HMKEOBBI_00933 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HMKEOBBI_00934 0.0 - - - EGP - - - Major Facilitator Superfamily
HMKEOBBI_00935 1.56e-37 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
HMKEOBBI_00936 1.11e-148 - - - K - - - WHG domain
HMKEOBBI_00937 4.3e-144 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
HMKEOBBI_00939 3.89e-68 - - - - - - - -
HMKEOBBI_00940 2.21e-41 - - - M - - - F5/8 type C domain
HMKEOBBI_00941 3.12e-244 - - - C - - - Aldo/keto reductase family
HMKEOBBI_00942 7.47e-123 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMKEOBBI_00943 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_00944 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HMKEOBBI_00946 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HMKEOBBI_00947 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HMKEOBBI_00948 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HMKEOBBI_00949 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
HMKEOBBI_00950 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
HMKEOBBI_00951 6.15e-127 - - - S - - - GtrA-like protein
HMKEOBBI_00952 0.0 - - - EGP - - - Major Facilitator Superfamily
HMKEOBBI_00953 1.3e-160 - - - G - - - Phosphoglycerate mutase family
HMKEOBBI_00954 9.77e-192 - - - - - - - -
HMKEOBBI_00955 2.03e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
HMKEOBBI_00956 5.05e-258 - - - P - - - NMT1/THI5 like
HMKEOBBI_00957 2.24e-157 - - - S - - - HAD hydrolase, family IA, variant 3
HMKEOBBI_00959 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMKEOBBI_00960 2.92e-124 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HMKEOBBI_00961 3.11e-84 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HMKEOBBI_00964 0.0 - - - S - - - Calcineurin-like phosphoesterase
HMKEOBBI_00965 9.2e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
HMKEOBBI_00966 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMKEOBBI_00967 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMKEOBBI_00968 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_00970 1.74e-251 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMKEOBBI_00971 5.26e-281 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
HMKEOBBI_00972 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMKEOBBI_00973 1.05e-292 - - - G - - - Transmembrane secretion effector
HMKEOBBI_00974 9.78e-169 - - - K - - - Bacterial regulatory proteins, tetR family
HMKEOBBI_00975 2.03e-185 - - - - - - - -
HMKEOBBI_00976 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMKEOBBI_00977 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMKEOBBI_00978 5.14e-222 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
HMKEOBBI_00979 2.08e-242 - - - - - - - -
HMKEOBBI_00980 4.83e-231 - - - - - - - -
HMKEOBBI_00981 2.52e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
HMKEOBBI_00982 1.71e-155 - - - S - - - CYTH
HMKEOBBI_00984 1.16e-120 - - - J - - - tRNA 5'-leader removal
HMKEOBBI_00985 3e-77 - - - - - - - -
HMKEOBBI_00986 1.01e-65 - - - - - - - -
HMKEOBBI_00987 0.0 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
HMKEOBBI_00988 1.82e-253 - - - L - - - Transposase and inactivated derivatives IS30 family
HMKEOBBI_00989 1.99e-80 - - - L - - - single-stranded DNA binding
HMKEOBBI_00990 1.14e-68 - - - - - - - -
HMKEOBBI_00991 5.43e-75 - - - - - - - -
HMKEOBBI_00992 2.92e-48 - - - - - - - -
HMKEOBBI_00993 1.36e-23 - - - - - - - -
HMKEOBBI_00994 1.17e-65 - - - - - - - -
HMKEOBBI_00995 9.04e-36 - - - - - - - -
HMKEOBBI_00997 3.98e-65 - - - K - - - Helix-turn-helix XRE-family like proteins
HMKEOBBI_00998 7.49e-09 - - - - - - - -
HMKEOBBI_00999 9.92e-280 - - - L - - - Phage integrase family
HMKEOBBI_01000 4.05e-17 - - - V - - - HNH nucleases
HMKEOBBI_01003 1.81e-20 - - - - - - - -
HMKEOBBI_01004 1.93e-276 - - - S - - - Terminase
HMKEOBBI_01005 3.14e-50 - - - S - - - Phage portal protein, SPP1 Gp6-like
HMKEOBBI_01006 1.05e-149 - - - S - - - Phage portal protein, SPP1 Gp6-like
HMKEOBBI_01007 5.57e-72 - - - - - - - -
HMKEOBBI_01008 3.86e-41 - - - - - - - -
HMKEOBBI_01009 2.68e-172 - - - S - - - Phage capsid family
HMKEOBBI_01010 1.64e-37 - - - - - - - -
HMKEOBBI_01011 1.78e-67 - - - S - - - Phage protein Gp19/Gp15/Gp42
HMKEOBBI_01012 6.92e-43 - - - - - - - -
HMKEOBBI_01013 5.14e-97 - - - N - - - domain, Protein
HMKEOBBI_01014 7.12e-39 - - - - - - - -
HMKEOBBI_01015 2.4e-55 - - - - - - - -
HMKEOBBI_01016 0.0 - - - S - - - phage tail tape measure protein
HMKEOBBI_01017 3.45e-127 - - - - - - - -
HMKEOBBI_01018 4.87e-280 - - - S - - - Phage minor structural protein
HMKEOBBI_01019 3.88e-141 - - - - - - - -
HMKEOBBI_01020 8.18e-49 - - - - - - - -
HMKEOBBI_01022 2.34e-131 - - - M - - - Glycosyl hydrolases family 25
HMKEOBBI_01023 1.1e-29 - - - - - - - -
HMKEOBBI_01024 6.05e-288 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HMKEOBBI_01025 1.05e-286 - - - S - - - MvaI/BcnI restriction endonuclease family
HMKEOBBI_01026 1.02e-89 - - - - - - - -
HMKEOBBI_01027 3.17e-179 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
HMKEOBBI_01028 2.88e-54 - - - L - - - Transposase, Mutator family
HMKEOBBI_01029 4.67e-300 - - - L - - - PFAM Integrase catalytic
HMKEOBBI_01030 1.35e-170 - - - L - - - IstB-like ATP binding protein
HMKEOBBI_01031 2.31e-115 - - - L - - - Transposase, Mutator family
HMKEOBBI_01033 4e-235 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
HMKEOBBI_01034 6.82e-25 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
HMKEOBBI_01035 5.92e-26 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
HMKEOBBI_01036 1.03e-196 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
HMKEOBBI_01038 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HMKEOBBI_01039 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
HMKEOBBI_01040 3.93e-230 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HMKEOBBI_01041 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HMKEOBBI_01042 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMKEOBBI_01043 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMKEOBBI_01044 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMKEOBBI_01045 1.79e-304 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HMKEOBBI_01046 5.51e-239 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMKEOBBI_01047 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
HMKEOBBI_01048 5.49e-85 - - - - - - - -
HMKEOBBI_01049 2.73e-76 - - - - - - - -
HMKEOBBI_01050 1.59e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01051 0.0 - - - V - - - Efflux ABC transporter, permease protein
HMKEOBBI_01052 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HMKEOBBI_01053 2e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HMKEOBBI_01054 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
HMKEOBBI_01055 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HMKEOBBI_01056 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
HMKEOBBI_01057 6.29e-274 - - - K - - - Psort location Cytoplasmic, score
HMKEOBBI_01058 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMKEOBBI_01059 6.1e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMKEOBBI_01060 2.89e-294 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
HMKEOBBI_01062 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMKEOBBI_01063 6.4e-164 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HMKEOBBI_01064 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HMKEOBBI_01065 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HMKEOBBI_01066 1.42e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HMKEOBBI_01067 1.73e-253 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HMKEOBBI_01068 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
HMKEOBBI_01069 1.26e-242 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMKEOBBI_01070 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMKEOBBI_01071 2.85e-54 - - - - - - - -
HMKEOBBI_01072 6.29e-55 - - - - - - - -
HMKEOBBI_01073 1.51e-227 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
HMKEOBBI_01074 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HMKEOBBI_01075 1.12e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HMKEOBBI_01076 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMKEOBBI_01077 2.34e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HMKEOBBI_01079 9.21e-52 - - - S - - - Parallel beta-helix repeats
HMKEOBBI_01080 9.43e-25 - - - E - - - Domain of unknown function (DUF5011)
HMKEOBBI_01081 5e-251 - - - L - - - PFAM Integrase catalytic
HMKEOBBI_01082 2.6e-185 istB - - L - - - IstB-like ATP binding protein
HMKEOBBI_01083 3.29e-53 - - - E - - - Domain of unknown function (DUF5011)
HMKEOBBI_01085 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMKEOBBI_01086 1.28e-174 - - - M - - - Protein of unknown function (DUF3152)
HMKEOBBI_01087 1.72e-247 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMKEOBBI_01088 3.39e-188 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMKEOBBI_01089 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
HMKEOBBI_01090 0.0 - - - M - - - domain protein
HMKEOBBI_01091 0.0 - - - M - - - LPXTG cell wall anchor motif
HMKEOBBI_01092 6.52e-271 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HMKEOBBI_01093 2.03e-147 - - - S - - - Domain of unknown function (DUF4854)
HMKEOBBI_01094 5.72e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
HMKEOBBI_01096 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMKEOBBI_01097 2.44e-168 - - - M - - - Mechanosensitive ion channel
HMKEOBBI_01098 1.51e-153 - - - K - - - Bacterial regulatory proteins, tetR family
HMKEOBBI_01099 1.37e-306 - - - S - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_01100 3.94e-294 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
HMKEOBBI_01101 9.14e-13 - - - M - - - Belongs to the glycosyl hydrolase 28 family
HMKEOBBI_01103 1.18e-85 - - - S ko:K06889 - ko00000 alpha beta
HMKEOBBI_01104 4.78e-54 - - - K - - - Transcriptional regulator
HMKEOBBI_01105 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HMKEOBBI_01107 1.9e-45 - - - - - - - -
HMKEOBBI_01112 2.11e-160 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
HMKEOBBI_01113 1.01e-292 - - - K - - - Helix-turn-helix XRE-family like proteins
HMKEOBBI_01114 4.54e-46 - - - I - - - carboxylic ester hydrolase activity
HMKEOBBI_01115 1.77e-72 - - - L - - - RelB antitoxin
HMKEOBBI_01117 9.29e-168 - - - K - - - helix_turn_helix, mercury resistance
HMKEOBBI_01118 7.08e-308 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HMKEOBBI_01120 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
HMKEOBBI_01121 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HMKEOBBI_01122 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
HMKEOBBI_01123 1.74e-278 steT - - E ko:K03294 - ko00000 amino acid
HMKEOBBI_01126 0.0 - - - - - - - -
HMKEOBBI_01127 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
HMKEOBBI_01128 3.78e-156 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
HMKEOBBI_01130 1.93e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
HMKEOBBI_01131 5.32e-108 - - - O - - - Hsp20/alpha crystallin family
HMKEOBBI_01132 9.36e-229 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HMKEOBBI_01133 1.08e-137 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMKEOBBI_01134 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HMKEOBBI_01135 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HMKEOBBI_01136 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HMKEOBBI_01137 5.28e-129 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HMKEOBBI_01138 1.64e-283 - - - S - - - Endonuclease/Exonuclease/phosphatase family
HMKEOBBI_01139 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMKEOBBI_01140 4.14e-212 - - - P - - - Cation efflux family
HMKEOBBI_01141 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMKEOBBI_01142 6.63e-174 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
HMKEOBBI_01143 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
HMKEOBBI_01144 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
HMKEOBBI_01145 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMKEOBBI_01146 3.01e-184 - - - - - - - -
HMKEOBBI_01147 8.83e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HMKEOBBI_01148 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HMKEOBBI_01149 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMKEOBBI_01150 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
HMKEOBBI_01151 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HMKEOBBI_01153 1.17e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMKEOBBI_01154 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMKEOBBI_01155 3.97e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMKEOBBI_01156 6.28e-225 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
HMKEOBBI_01159 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HMKEOBBI_01160 2.09e-272 - - - - - - - -
HMKEOBBI_01162 6.19e-263 - - - - - - - -
HMKEOBBI_01164 4.87e-155 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
HMKEOBBI_01165 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
HMKEOBBI_01166 8.95e-74 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
HMKEOBBI_01167 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01168 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_01169 8.57e-222 - - - K - - - Putative sugar-binding domain
HMKEOBBI_01170 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMKEOBBI_01171 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HMKEOBBI_01172 6.29e-220 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
HMKEOBBI_01173 4.86e-166 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
HMKEOBBI_01174 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMKEOBBI_01175 1.03e-201 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMKEOBBI_01176 1.9e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMKEOBBI_01177 5.12e-266 - - - K - - - helix_turn _helix lactose operon repressor
HMKEOBBI_01179 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HMKEOBBI_01180 2.37e-198 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMKEOBBI_01181 4.7e-143 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMKEOBBI_01184 7.08e-148 - - - G - - - Glycosyl hydrolases family 43
HMKEOBBI_01185 1.79e-142 - - - G - - - Glycosyl hydrolases family 43
HMKEOBBI_01186 1.61e-258 - - - K - - - helix_turn _helix lactose operon repressor
HMKEOBBI_01187 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
HMKEOBBI_01188 2.77e-158 - - - L - - - Protein of unknown function (DUF1524)
HMKEOBBI_01189 2.93e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HMKEOBBI_01190 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HMKEOBBI_01191 1.53e-123 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HMKEOBBI_01192 8.83e-147 - - - L ko:K07483 - ko00000 Integrase core domain
HMKEOBBI_01193 9.03e-56 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_01194 0.0 - - - - - - - -
HMKEOBBI_01195 2.49e-230 - - - S ko:K21688 - ko00000 G5
HMKEOBBI_01196 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
HMKEOBBI_01197 3.88e-152 - - - F - - - Domain of unknown function (DUF4916)
HMKEOBBI_01198 1.2e-204 - - - I - - - Alpha/beta hydrolase family
HMKEOBBI_01200 0.0 - - - S - - - L,D-transpeptidase catalytic domain
HMKEOBBI_01201 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HMKEOBBI_01202 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
HMKEOBBI_01203 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
HMKEOBBI_01204 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMKEOBBI_01205 8.97e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
HMKEOBBI_01206 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HMKEOBBI_01207 0.0 pon1 - - M - - - Transglycosylase
HMKEOBBI_01208 3.02e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HMKEOBBI_01209 2.85e-289 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HMKEOBBI_01210 7e-186 - - - K - - - DeoR C terminal sensor domain
HMKEOBBI_01211 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
HMKEOBBI_01212 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
HMKEOBBI_01213 1.32e-308 - - - EGP - - - Sugar (and other) transporter
HMKEOBBI_01214 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HMKEOBBI_01215 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
HMKEOBBI_01216 8.76e-234 - - - S - - - Membrane
HMKEOBBI_01217 5.27e-156 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMKEOBBI_01218 6.75e-76 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
HMKEOBBI_01219 3.46e-43 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
HMKEOBBI_01220 2.13e-234 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
HMKEOBBI_01221 1.94e-144 - - - - - - - -
HMKEOBBI_01222 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKEOBBI_01223 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKEOBBI_01224 5.36e-124 - - - T - - - Forkhead associated domain
HMKEOBBI_01225 1.2e-100 - - - B - - - Belongs to the OprB family
HMKEOBBI_01226 9.56e-211 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
HMKEOBBI_01227 0.0 - - - E - - - Transglutaminase-like superfamily
HMKEOBBI_01228 6.42e-299 - - - S - - - Protein of unknown function DUF58
HMKEOBBI_01229 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HMKEOBBI_01230 0.0 - - - S - - - Fibronectin type 3 domain
HMKEOBBI_01231 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HMKEOBBI_01232 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
HMKEOBBI_01233 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
HMKEOBBI_01234 2.39e-195 - - - K - - - -acetyltransferase
HMKEOBBI_01235 0.0 - - - G - - - Major Facilitator Superfamily
HMKEOBBI_01236 3.56e-86 gsiA - - P ko:K02031,ko:K02032,ko:K12371,ko:K13892 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMKEOBBI_01237 8.46e-55 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
HMKEOBBI_01238 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HMKEOBBI_01239 1.19e-75 - - - L - - - Transposase
HMKEOBBI_01240 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMKEOBBI_01241 6.97e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMKEOBBI_01242 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMKEOBBI_01243 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
HMKEOBBI_01244 0.0 vpr - - O - - - Subtilase family
HMKEOBBI_01245 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMKEOBBI_01246 3.18e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMKEOBBI_01247 0.0 - - - S - - - zinc finger
HMKEOBBI_01248 2.43e-129 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HMKEOBBI_01249 7.65e-293 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
HMKEOBBI_01250 1.3e-200 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HMKEOBBI_01251 4.8e-171 tmp1 - - S - - - Domain of unknown function (DUF4391)
HMKEOBBI_01252 8.74e-193 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HMKEOBBI_01253 0.0 - - - OP - - - Sulfurtransferase TusA
HMKEOBBI_01254 4.73e-234 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HMKEOBBI_01255 5.95e-05 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMKEOBBI_01257 2.23e-258 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
HMKEOBBI_01258 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMKEOBBI_01259 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMKEOBBI_01260 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
HMKEOBBI_01261 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMKEOBBI_01263 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
HMKEOBBI_01264 4.55e-212 - - - - - - - -
HMKEOBBI_01265 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
HMKEOBBI_01269 2.53e-240 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKEOBBI_01270 1.06e-197 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01271 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
HMKEOBBI_01272 1.5e-209 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_01273 1.72e-218 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMKEOBBI_01274 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HMKEOBBI_01275 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMKEOBBI_01276 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMKEOBBI_01277 3.42e-84 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
HMKEOBBI_01278 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_01279 4.22e-160 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HMKEOBBI_01280 2.17e-243 - - - K - - - Periplasmic binding protein domain
HMKEOBBI_01281 3.53e-25 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMKEOBBI_01282 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HMKEOBBI_01284 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMKEOBBI_01285 4.8e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HMKEOBBI_01286 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
HMKEOBBI_01287 8.77e-179 hflK - - O - - - prohibitin homologues
HMKEOBBI_01288 1.81e-310 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMKEOBBI_01289 3.15e-298 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMKEOBBI_01290 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
HMKEOBBI_01291 9.17e-284 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HMKEOBBI_01292 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01293 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HMKEOBBI_01294 2.11e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
HMKEOBBI_01295 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
HMKEOBBI_01296 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
HMKEOBBI_01297 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HMKEOBBI_01298 1.56e-186 - - - S - - - Short repeat of unknown function (DUF308)
HMKEOBBI_01299 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
HMKEOBBI_01300 1.9e-154 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
HMKEOBBI_01301 1.28e-217 - - - - - - - -
HMKEOBBI_01302 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMKEOBBI_01303 2.45e-230 - - - I - - - PAP2 superfamily
HMKEOBBI_01304 1.5e-47 - - - NU - - - Tfp pilus assembly protein FimV
HMKEOBBI_01305 0.0 - - - L - - - PIF1-like helicase
HMKEOBBI_01306 6.98e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMKEOBBI_01307 1.91e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HMKEOBBI_01308 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HMKEOBBI_01309 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMKEOBBI_01310 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
HMKEOBBI_01311 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
HMKEOBBI_01312 3.71e-78 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
HMKEOBBI_01313 5.94e-237 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMKEOBBI_01314 2.35e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMKEOBBI_01315 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HMKEOBBI_01317 5.15e-247 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
HMKEOBBI_01318 1.58e-208 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
HMKEOBBI_01319 1.92e-239 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HMKEOBBI_01320 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
HMKEOBBI_01321 3.57e-144 - - - - - - - -
HMKEOBBI_01322 2.66e-217 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
HMKEOBBI_01323 7.95e-189 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HMKEOBBI_01324 0.0 - - - JKL - - - helicase superfamily c-terminal domain
HMKEOBBI_01325 1.23e-210 - - - EG - - - EamA-like transporter family
HMKEOBBI_01326 4.81e-185 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMKEOBBI_01327 3.93e-189 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HMKEOBBI_01329 7.33e-271 - - - S - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_01330 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
HMKEOBBI_01331 4.43e-58 - - - C - - - Aldo/keto reductase family
HMKEOBBI_01332 1.94e-94 - - - EGP - - - Major facilitator superfamily
HMKEOBBI_01333 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMKEOBBI_01334 0.0 - - - S - - - ATPases associated with a variety of cellular activities
HMKEOBBI_01335 2.9e-75 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
HMKEOBBI_01336 1.7e-200 - - - I - - - alpha/beta hydrolase fold
HMKEOBBI_01337 4.04e-149 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
HMKEOBBI_01339 7.29e-65 - - - S - - - DUF218 domain
HMKEOBBI_01340 8.79e-139 - - - S - - - Protein of unknown function (DUF969)
HMKEOBBI_01341 1.54e-201 - - - S - - - Protein of unknown function (DUF979)
HMKEOBBI_01342 2.05e-146 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMKEOBBI_01344 1.76e-161 - - - - - - - -
HMKEOBBI_01345 1.66e-224 - - - M - - - domain, Protein
HMKEOBBI_01346 8.64e-24 - - - M - - - domain, Protein
HMKEOBBI_01347 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
HMKEOBBI_01348 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
HMKEOBBI_01349 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
HMKEOBBI_01350 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
HMKEOBBI_01351 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMKEOBBI_01352 1.12e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMKEOBBI_01353 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HMKEOBBI_01354 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMKEOBBI_01355 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HMKEOBBI_01356 3.48e-269 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMKEOBBI_01357 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
HMKEOBBI_01358 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HMKEOBBI_01359 2.26e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01360 3.97e-295 - - - M - - - Glycosyl transferase family 21
HMKEOBBI_01361 0.0 - - - S - - - AI-2E family transporter
HMKEOBBI_01362 1.89e-227 - - - M - - - Glycosyltransferase like family 2
HMKEOBBI_01363 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
HMKEOBBI_01366 4.46e-100 - - - S - - - Domain of unknown function (DUF4190)
HMKEOBBI_01367 4.62e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HMKEOBBI_01368 2.24e-194 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMKEOBBI_01370 6.43e-16 - - - - - - - -
HMKEOBBI_01371 3.18e-30 - - - - - - - -
HMKEOBBI_01372 3.68e-296 - - - S - - - Helix-turn-helix domain
HMKEOBBI_01373 4.34e-126 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
HMKEOBBI_01374 2.08e-133 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
HMKEOBBI_01375 1.43e-47 - - - - - - - -
HMKEOBBI_01376 1.03e-91 - - - - - - - -
HMKEOBBI_01377 3.5e-36 - - - - - - - -
HMKEOBBI_01378 6.52e-157 - - - K - - - Helix-turn-helix domain protein
HMKEOBBI_01380 0.0 - - - M - - - Cell surface antigen C-terminus
HMKEOBBI_01381 2.3e-56 - - - V ko:K01992 - ko00000,ko00002,ko02000 PFAM ABC-2 type transporter
HMKEOBBI_01382 4.07e-50 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
HMKEOBBI_01385 2.76e-104 - - - - - - - -
HMKEOBBI_01386 3.3e-138 - - - - - - - -
HMKEOBBI_01387 8.73e-154 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMKEOBBI_01388 1.98e-125 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HMKEOBBI_01389 4.57e-248 - - - - - - - -
HMKEOBBI_01390 6.87e-172 - - - V - - - ABC transporter
HMKEOBBI_01391 1.35e-239 - - - V - - - Putative peptidoglycan binding domain
HMKEOBBI_01392 2.29e-154 - - - - - - - -
HMKEOBBI_01393 1.03e-77 - - - - - - - -
HMKEOBBI_01394 1.02e-153 - - - K - - - Transcriptional regulatory protein, C terminal
HMKEOBBI_01395 1.1e-296 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 GHKL domain
HMKEOBBI_01396 1e-125 - - - K - - - transcriptional regulator
HMKEOBBI_01397 1.78e-57 - - - - - - - -
HMKEOBBI_01398 1.44e-42 - - - - - - - -
HMKEOBBI_01399 2.17e-183 - - - - - - - -
HMKEOBBI_01400 7.5e-83 - - - S - - - PrgI family protein
HMKEOBBI_01401 0.0 - - - U - - - type IV secretory pathway VirB4
HMKEOBBI_01402 3.71e-265 - - - M - - - CHAP domain
HMKEOBBI_01403 4.29e-91 - - - - - - - -
HMKEOBBI_01404 2.16e-117 - - - - - - - -
HMKEOBBI_01405 1.12e-74 - - - - - - - -
HMKEOBBI_01408 1.1e-155 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMKEOBBI_01411 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
HMKEOBBI_01412 7.01e-83 - - - - - - - -
HMKEOBBI_01413 5.65e-60 - - - - - - - -
HMKEOBBI_01414 6.3e-161 - - - - - - - -
HMKEOBBI_01415 1.33e-312 - - - S - - - Antirestriction protein (ArdA)
HMKEOBBI_01416 5.98e-169 - - - - - - - -
HMKEOBBI_01417 2.79e-184 - - - S - - - Protein of unknown function (DUF3801)
HMKEOBBI_01418 1.89e-311 - - - U - - - Relaxase/Mobilisation nuclease domain
HMKEOBBI_01419 1.08e-88 - - - S - - - Bacterial mobilisation protein (MobC)
HMKEOBBI_01420 1.96e-96 - - - - - - - -
HMKEOBBI_01421 6.28e-54 - - - - - - - -
HMKEOBBI_01422 4.13e-308 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
HMKEOBBI_01423 3.49e-126 - - - S - - - Domain of unknown function (DUF4192)
HMKEOBBI_01424 2.09e-205 - - - T - - - Histidine kinase
HMKEOBBI_01425 8.98e-139 - - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_01426 4.92e-89 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01427 2.01e-20 - - - - - - - -
HMKEOBBI_01428 8.1e-220 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMKEOBBI_01429 5.42e-41 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMKEOBBI_01430 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HMKEOBBI_01431 1.22e-100 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01432 2.4e-91 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMKEOBBI_01433 1.12e-60 - - - T - - - Histidine kinase
HMKEOBBI_01434 1.16e-95 - - - K - - - Bacterial regulatory proteins, luxR family
HMKEOBBI_01435 2.69e-95 - - - KLT - - - serine threonine protein kinase
HMKEOBBI_01437 1.47e-35 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Protease II
HMKEOBBI_01438 3.37e-90 - - - G - - - Glycosyl hydrolase family 20, domain 2
HMKEOBBI_01439 8.68e-293 intA - - L - - - Phage integrase family
HMKEOBBI_01440 1.27e-10 intA - - L - - - Phage integrase family
HMKEOBBI_01443 1.66e-283 intA - - L - - - Phage integrase family
HMKEOBBI_01444 1.31e-108 - - - - - - - -
HMKEOBBI_01445 9.25e-27 - - - S - - - Helix-turn-helix domain
HMKEOBBI_01446 7.77e-24 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
HMKEOBBI_01447 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HMKEOBBI_01448 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_01449 5.98e-111 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HMKEOBBI_01450 9.07e-228 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HMKEOBBI_01451 1.35e-299 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMKEOBBI_01452 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
HMKEOBBI_01454 3.34e-131 - - - - - - - -
HMKEOBBI_01455 6.51e-234 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
HMKEOBBI_01456 1.11e-138 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01457 4.81e-236 - - - - - - - -
HMKEOBBI_01458 2.57e-14 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HMKEOBBI_01459 1.25e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HMKEOBBI_01460 7.89e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HMKEOBBI_01461 3.41e-143 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_01462 1.55e-66 - - - E - - - Branched-chain amino acid transport protein (AzlD)
HMKEOBBI_01463 1.04e-248 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HMKEOBBI_01464 2e-125 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
HMKEOBBI_01465 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
HMKEOBBI_01466 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMKEOBBI_01467 1.52e-94 - - - O - - - OsmC-like protein
HMKEOBBI_01468 1.31e-244 - - - T - - - Universal stress protein family
HMKEOBBI_01469 9.72e-153 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HMKEOBBI_01470 1.05e-231 - - - S - - - CHAP domain
HMKEOBBI_01471 2e-274 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMKEOBBI_01472 4.6e-53 - - - - - - - -
HMKEOBBI_01473 3.76e-287 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMKEOBBI_01474 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HMKEOBBI_01475 2.85e-13 - - - EGP - - - Major Facilitator Superfamily
HMKEOBBI_01476 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMKEOBBI_01477 2.37e-223 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HMKEOBBI_01478 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HMKEOBBI_01480 3.69e-278 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
HMKEOBBI_01481 0.0 - - - S - - - Domain of unknown function (DUF4037)
HMKEOBBI_01482 2.25e-144 - - - S - - - Protein of unknown function (DUF4125)
HMKEOBBI_01483 2.71e-195 - - - - - - - -
HMKEOBBI_01484 0.0 pspC - - KT - - - PspC domain
HMKEOBBI_01485 0.0 tcsS3 - - KT - - - PspC domain
HMKEOBBI_01486 5.87e-163 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
HMKEOBBI_01487 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMKEOBBI_01488 5.83e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HMKEOBBI_01489 4.36e-239 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
HMKEOBBI_01490 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMKEOBBI_01491 2.95e-121 - - - - - - - -
HMKEOBBI_01493 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HMKEOBBI_01495 1.21e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMKEOBBI_01496 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
HMKEOBBI_01497 1.12e-270 - - - I - - - Diacylglycerol kinase catalytic domain
HMKEOBBI_01498 5.91e-197 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMKEOBBI_01499 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
HMKEOBBI_01501 1.74e-95 - - - M - - - Spy0128-like isopeptide containing domain
HMKEOBBI_01503 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HMKEOBBI_01504 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMKEOBBI_01505 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HMKEOBBI_01506 2.41e-258 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMKEOBBI_01507 7.42e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMKEOBBI_01508 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
HMKEOBBI_01509 1.63e-140 - - - - - - - -
HMKEOBBI_01510 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMKEOBBI_01511 6.67e-300 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
HMKEOBBI_01512 2.35e-290 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMKEOBBI_01513 1.77e-123 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMKEOBBI_01514 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMKEOBBI_01515 8.14e-242 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HMKEOBBI_01516 4.96e-222 - - - - - - - -
HMKEOBBI_01517 3.08e-110 tnp3503b - - L - - - Transposase and inactivated derivatives
HMKEOBBI_01519 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
HMKEOBBI_01520 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
HMKEOBBI_01521 2.01e-219 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMKEOBBI_01522 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
HMKEOBBI_01523 3.77e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HMKEOBBI_01524 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKEOBBI_01525 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMKEOBBI_01526 2.84e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMKEOBBI_01527 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HMKEOBBI_01528 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMKEOBBI_01529 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMKEOBBI_01530 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMKEOBBI_01531 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HMKEOBBI_01532 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
HMKEOBBI_01533 5.38e-147 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMKEOBBI_01534 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMKEOBBI_01535 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMKEOBBI_01536 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMKEOBBI_01537 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMKEOBBI_01538 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMKEOBBI_01539 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMKEOBBI_01540 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMKEOBBI_01541 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMKEOBBI_01542 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HMKEOBBI_01543 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMKEOBBI_01544 5.27e-159 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMKEOBBI_01545 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMKEOBBI_01546 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMKEOBBI_01547 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMKEOBBI_01548 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMKEOBBI_01549 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HMKEOBBI_01550 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMKEOBBI_01551 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HMKEOBBI_01552 8.68e-24 - - - S - - - YwiC-like protein
HMKEOBBI_01553 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HMKEOBBI_01554 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HMKEOBBI_01555 2.39e-295 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HMKEOBBI_01556 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HMKEOBBI_01557 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HMKEOBBI_01558 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMKEOBBI_01559 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HMKEOBBI_01560 7.22e-153 - - - - - - - -
HMKEOBBI_01561 1.63e-146 yigZ - - S - - - Uncharacterized protein family UPF0029
HMKEOBBI_01562 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
HMKEOBBI_01564 1.74e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMKEOBBI_01565 5.74e-285 dapC - - E - - - Aminotransferase class I and II
HMKEOBBI_01566 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
HMKEOBBI_01567 4.5e-279 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HMKEOBBI_01568 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
HMKEOBBI_01572 3.93e-74 - - - KLT - - - Associated with various cellular activities
HMKEOBBI_01573 2.01e-165 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HMKEOBBI_01574 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMKEOBBI_01575 7.19e-256 - - - - - - - -
HMKEOBBI_01576 9.98e-121 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMKEOBBI_01577 5.69e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
HMKEOBBI_01578 1.88e-51 - - - S - - - Putative regulatory protein
HMKEOBBI_01579 2.1e-141 - - - NO - - - SAF
HMKEOBBI_01580 1.66e-55 - - - - - - - -
HMKEOBBI_01581 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
HMKEOBBI_01582 0.0 - - - T - - - Forkhead associated domain
HMKEOBBI_01584 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMKEOBBI_01585 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMKEOBBI_01586 5.87e-229 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
HMKEOBBI_01587 0.0 - - - G - - - BNR repeat-like domain
HMKEOBBI_01589 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
HMKEOBBI_01591 1.74e-217 - - - S - - - Protein conserved in bacteria
HMKEOBBI_01592 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMKEOBBI_01593 7.7e-233 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HMKEOBBI_01594 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HMKEOBBI_01595 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
HMKEOBBI_01596 5.44e-165 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HMKEOBBI_01597 8.66e-310 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HMKEOBBI_01598 2.57e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMKEOBBI_01599 0.0 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMKEOBBI_01600 2.45e-61 - - - - - - - -
HMKEOBBI_01601 9.16e-182 nfrA - - C - - - Nitroreductase family
HMKEOBBI_01602 5.82e-89 - - - S - - - Protein of unknown function (DUF4235)
HMKEOBBI_01603 3.05e-179 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HMKEOBBI_01605 2.63e-241 - - - K - - - Psort location Cytoplasmic, score
HMKEOBBI_01606 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
HMKEOBBI_01607 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HMKEOBBI_01608 8.46e-88 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMKEOBBI_01609 1.35e-236 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
HMKEOBBI_01610 6.42e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
HMKEOBBI_01611 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
HMKEOBBI_01612 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
HMKEOBBI_01613 1.17e-171 - - - S - - - HAD hydrolase, family IA, variant 3
HMKEOBBI_01615 2.18e-162 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HMKEOBBI_01616 5.14e-219 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMKEOBBI_01617 1.6e-83 - - - - - - - -
HMKEOBBI_01618 7.68e-170 - - - - - - - -
HMKEOBBI_01619 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMKEOBBI_01620 1.2e-107 - - - K - - - Transcriptional regulator
HMKEOBBI_01622 0.0 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
HMKEOBBI_01623 1.29e-235 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
HMKEOBBI_01624 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HMKEOBBI_01626 3.34e-211 - - - S - - - Glutamine amidotransferase domain
HMKEOBBI_01627 3.28e-176 - - - T ko:K06950 - ko00000 HD domain
HMKEOBBI_01628 3.15e-259 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01629 0.0 - - - V - - - ABC transporter permease
HMKEOBBI_01630 0.0 - - - H - - - Protein of unknown function (DUF4012)
HMKEOBBI_01631 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HMKEOBBI_01632 5.53e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HMKEOBBI_01633 1.99e-36 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
HMKEOBBI_01634 0.0 - - - - - - - -
HMKEOBBI_01635 7.47e-267 - - - S - - - Glycosyltransferase, group 2 family protein
HMKEOBBI_01636 9.1e-39 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMKEOBBI_01637 2.88e-25 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HMKEOBBI_01638 8.69e-129 - - - - - - - -
HMKEOBBI_01639 1.1e-282 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
HMKEOBBI_01640 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMKEOBBI_01642 1.34e-196 - - - D - - - bacterial-type flagellum organization
HMKEOBBI_01643 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
HMKEOBBI_01644 2.62e-157 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
HMKEOBBI_01646 1.3e-20 - - - NU - - - Type II secretion system (T2SS), protein F
HMKEOBBI_01647 3.96e-55 - - - S - - - Protein of unknown function (DUF4244)
HMKEOBBI_01648 1.04e-72 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
HMKEOBBI_01649 1.61e-274 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
HMKEOBBI_01650 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
HMKEOBBI_01651 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMKEOBBI_01652 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HMKEOBBI_01653 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HMKEOBBI_01655 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMKEOBBI_01656 1.77e-148 - - - - - - - -
HMKEOBBI_01657 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HMKEOBBI_01658 3.11e-19 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
HMKEOBBI_01659 0.0 - - - S - - - Calcineurin-like phosphoesterase
HMKEOBBI_01660 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMKEOBBI_01661 0.0 pbp5 - - M - - - Transglycosylase
HMKEOBBI_01662 1.8e-295 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HMKEOBBI_01663 5.69e-176 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HMKEOBBI_01664 0.0 - - - M - - - PA domain
HMKEOBBI_01665 3.23e-251 - - - I - - - PAP2 superfamily
HMKEOBBI_01666 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMKEOBBI_01667 4.2e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMKEOBBI_01668 5.19e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HMKEOBBI_01669 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_01670 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HMKEOBBI_01671 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMKEOBBI_01672 7.68e-62 - - - S - - - Fic/DOC family
HMKEOBBI_01673 4.24e-49 - - - S - - - Fic/DOC family
HMKEOBBI_01674 3.88e-250 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMKEOBBI_01676 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
HMKEOBBI_01677 4.8e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
HMKEOBBI_01678 8.34e-294 - - - S - - - Predicted membrane protein (DUF2318)
HMKEOBBI_01679 2.54e-286 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HMKEOBBI_01680 9e-279 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMKEOBBI_01681 2.6e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_01682 8.08e-103 - - - S - - - FMN_bind
HMKEOBBI_01683 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
HMKEOBBI_01684 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
HMKEOBBI_01685 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKEOBBI_01686 5.95e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMKEOBBI_01687 2.92e-63 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HMKEOBBI_01688 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
HMKEOBBI_01689 1.94e-38 - - - Q - - - phosphatase activity
HMKEOBBI_01690 2.24e-103 - - - - - - - -
HMKEOBBI_01691 2.65e-306 - - - S - - - Putative ABC-transporter type IV
HMKEOBBI_01692 1.72e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMKEOBBI_01694 8.89e-111 - - - E - - - IrrE N-terminal-like domain
HMKEOBBI_01695 9.77e-51 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
HMKEOBBI_01696 2.35e-156 - - - L ko:K07483 - ko00000 Integrase core domain
HMKEOBBI_01698 9.34e-106 - - - K - - - Winged helix DNA-binding domain
HMKEOBBI_01699 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HMKEOBBI_01700 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HMKEOBBI_01701 6.48e-104 - - - - - - - -
HMKEOBBI_01702 1.82e-67 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HMKEOBBI_01704 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HMKEOBBI_01705 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
HMKEOBBI_01706 6.85e-255 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
HMKEOBBI_01707 1.36e-171 icaR - - K - - - Bacterial regulatory proteins, tetR family
HMKEOBBI_01709 6.11e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMKEOBBI_01710 2.1e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
HMKEOBBI_01711 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
HMKEOBBI_01712 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
HMKEOBBI_01713 0.0 dinF - - V - - - MatE
HMKEOBBI_01714 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HMKEOBBI_01715 0.0 murE - - M - - - Domain of unknown function (DUF1727)
HMKEOBBI_01716 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HMKEOBBI_01717 3.15e-44 - - - S - - - granule-associated protein
HMKEOBBI_01718 0.0 - - - S ko:K03688 - ko00000 ABC1 family
HMKEOBBI_01719 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HMKEOBBI_01720 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
HMKEOBBI_01721 2.51e-298 rmuC - - S ko:K09760 - ko00000 RmuC family
HMKEOBBI_01722 3.51e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMKEOBBI_01723 2.26e-212 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
HMKEOBBI_01724 1.17e-75 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01725 7.99e-73 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMKEOBBI_01727 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMKEOBBI_01728 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMKEOBBI_01729 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMKEOBBI_01730 1.96e-251 - - - J - - - Acetyltransferase (GNAT) domain
HMKEOBBI_01731 6.51e-69 - - - S - - - Protein of unknown function (DUF2469)
HMKEOBBI_01732 0.0 - - - H - - - Flavin containing amine oxidoreductase
HMKEOBBI_01733 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMKEOBBI_01734 8.37e-298 - 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HMKEOBBI_01735 1.56e-109 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
HMKEOBBI_01736 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
HMKEOBBI_01737 0.0 - - - S - - - domain protein
HMKEOBBI_01738 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMKEOBBI_01739 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMKEOBBI_01740 2.82e-160 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMKEOBBI_01741 4.39e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
HMKEOBBI_01742 5.6e-170 - - - - - - - -
HMKEOBBI_01743 8.19e-134 mntP - - P - - - Probably functions as a manganese efflux pump
HMKEOBBI_01745 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HMKEOBBI_01746 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HMKEOBBI_01747 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
HMKEOBBI_01748 8.85e-47 - - - - - - - -
HMKEOBBI_01750 2.94e-265 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMKEOBBI_01751 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HMKEOBBI_01753 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMKEOBBI_01754 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMKEOBBI_01755 8.04e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMKEOBBI_01756 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMKEOBBI_01757 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMKEOBBI_01758 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMKEOBBI_01759 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HMKEOBBI_01760 1.06e-166 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HMKEOBBI_01761 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
HMKEOBBI_01762 0.0 - - - - - - - -
HMKEOBBI_01763 4.55e-194 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HMKEOBBI_01764 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HMKEOBBI_01765 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HMKEOBBI_01766 0.0 pccB - - I - - - Carboxyl transferase domain
HMKEOBBI_01767 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
HMKEOBBI_01768 6.8e-129 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMKEOBBI_01769 1.64e-204 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HMKEOBBI_01771 3.54e-167 - - - L - - - Phage integrase, N-terminal SAM-like domain
HMKEOBBI_01773 1.77e-101 - - - OU - - - Serine dehydrogenase proteinase
HMKEOBBI_01776 1.58e-75 - - - - - - - -
HMKEOBBI_01777 3.76e-82 - - - S - - - Bacterial PH domain
HMKEOBBI_01778 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HMKEOBBI_01779 1.28e-154 - - - - - - - -
HMKEOBBI_01780 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMKEOBBI_01781 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMKEOBBI_01782 1.16e-145 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
HMKEOBBI_01783 2.16e-122 lemA - - S ko:K03744 - ko00000 LemA family
HMKEOBBI_01784 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HMKEOBBI_01785 5.25e-94 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMKEOBBI_01786 3.66e-241 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMKEOBBI_01787 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMKEOBBI_01788 1.36e-125 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HMKEOBBI_01789 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HMKEOBBI_01790 2.79e-213 - - - C - - - Oxidoreductase, aldo keto reductase family protein
HMKEOBBI_01791 2.86e-117 - - - L - - - Transposase and inactivated derivatives IS30 family
HMKEOBBI_01792 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
HMKEOBBI_01793 7.85e-241 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
HMKEOBBI_01794 9.04e-186 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMKEOBBI_01795 2.23e-164 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMKEOBBI_01796 7.09e-120 - - - D - - - nuclear chromosome segregation
HMKEOBBI_01797 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HMKEOBBI_01798 2.9e-231 - - - L - - - Excalibur calcium-binding domain
HMKEOBBI_01799 8.01e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMKEOBBI_01800 6.65e-314 - - - EGP - - - Major Facilitator Superfamily
HMKEOBBI_01801 1.71e-138 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMKEOBBI_01802 1.7e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
HMKEOBBI_01803 5.39e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HMKEOBBI_01804 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMKEOBBI_01805 2.7e-184 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HMKEOBBI_01806 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
HMKEOBBI_01807 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
HMKEOBBI_01808 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
HMKEOBBI_01809 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HMKEOBBI_01811 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMKEOBBI_01812 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
HMKEOBBI_01813 7.99e-193 - - - - - - - -
HMKEOBBI_01814 5.45e-232 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HMKEOBBI_01815 1.52e-309 - - - M - - - LPXTG-motif cell wall anchor domain protein
HMKEOBBI_01816 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
HMKEOBBI_01817 4.46e-132 - - - L - - - Helix-turn-helix domain
HMKEOBBI_01818 2.18e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMKEOBBI_01819 3.11e-220 - - - K - - - Psort location Cytoplasmic, score
HMKEOBBI_01820 0.0 - - - KLT - - - Protein tyrosine kinase
HMKEOBBI_01821 2.59e-201 - - - O - - - Thioredoxin
HMKEOBBI_01823 1.08e-276 rpfB - - S ko:K21688 - ko00000 G5
HMKEOBBI_01824 8.92e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMKEOBBI_01825 2.19e-212 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMKEOBBI_01826 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
HMKEOBBI_01827 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
HMKEOBBI_01828 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
HMKEOBBI_01829 0.0 - - - M - - - Conserved repeat domain
HMKEOBBI_01830 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
HMKEOBBI_01831 6.8e-259 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMKEOBBI_01832 1.7e-313 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HMKEOBBI_01833 3.68e-230 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HMKEOBBI_01834 4.29e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HMKEOBBI_01835 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
HMKEOBBI_01836 2.02e-225 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
HMKEOBBI_01837 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HMKEOBBI_01838 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMKEOBBI_01839 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMKEOBBI_01840 1.79e-304 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMKEOBBI_01841 5.54e-125 - - - S - - - Protein of unknown function (DUF721)
HMKEOBBI_01842 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMKEOBBI_01843 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMKEOBBI_01844 1.44e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
HMKEOBBI_01846 4.34e-240 - - - G - - - Glycosyl hydrolases family 43
HMKEOBBI_01847 4.42e-238 - - - K - - - Periplasmic binding protein domain
HMKEOBBI_01848 4.38e-289 - - - I - - - Serine aminopeptidase, S33
HMKEOBBI_01849 9.05e-12 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_01850 2.87e-56 - - - S - - - Protein of unknown function (DUF2442)
HMKEOBBI_01851 2.73e-19 - - - S - - - Domain of unknown function (DUF4160)
HMKEOBBI_01852 8.24e-21 - - - K - - - Helix-turn-helix domain
HMKEOBBI_01856 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HMKEOBBI_01857 3e-158 gntR - - K - - - FCD
HMKEOBBI_01858 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMKEOBBI_01859 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
HMKEOBBI_01862 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
HMKEOBBI_01863 4.91e-242 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_01864 1.03e-100 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKEOBBI_01865 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMKEOBBI_01866 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMKEOBBI_01867 2.08e-175 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
HMKEOBBI_01868 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HMKEOBBI_01869 9.86e-241 - - - EG - - - EamA-like transporter family
HMKEOBBI_01870 3.36e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
HMKEOBBI_01871 2.1e-67 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMKEOBBI_01872 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HMKEOBBI_01873 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
HMKEOBBI_01874 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HMKEOBBI_01875 1.95e-308 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HMKEOBBI_01876 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMKEOBBI_01877 0.0 - - - S - - - Threonine/Serine exporter, ThrE
HMKEOBBI_01878 7.63e-228 - - - S - - - Amidohydrolase family
HMKEOBBI_01879 1.3e-215 - - - L - - - Transposase and inactivated derivatives IS30 family
HMKEOBBI_01880 4.09e-249 - - - S - - - Protein conserved in bacteria
HMKEOBBI_01881 1.2e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMKEOBBI_01882 1.22e-63 - - - S - - - Protein of unknown function (DUF3073)
HMKEOBBI_01883 1.05e-114 - - - K - - - LytTr DNA-binding domain
HMKEOBBI_01884 1.79e-79 - - - T - - - protein histidine kinase activity
HMKEOBBI_01885 3.55e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMKEOBBI_01886 2.43e-40 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HMKEOBBI_01887 2.63e-270 - - - M - - - Glycosyl hydrolases family 25
HMKEOBBI_01888 5.24e-298 - - - H - - - Flavin containing amine oxidoreductase
HMKEOBBI_01889 6.46e-27 - - - - - - - -
HMKEOBBI_01890 2.86e-144 - - - L - - - Transposase, Mutator family
HMKEOBBI_01891 4.29e-256 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMKEOBBI_01892 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMKEOBBI_01893 1.4e-203 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMKEOBBI_01894 6.84e-96 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HMKEOBBI_01895 1.96e-132 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMKEOBBI_01896 1.24e-109 - - - M - - - Polysaccharide pyruvyl transferase
HMKEOBBI_01897 2.39e-136 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
HMKEOBBI_01898 6.18e-86 - - GT2 S ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase like family 2
HMKEOBBI_01899 1.55e-141 - - - M - - - Glycosyltransferase like family 2
HMKEOBBI_01900 4.85e-185 istB - - L - - - IstB-like ATP binding protein
HMKEOBBI_01901 7.82e-278 - - - L - - - PFAM Integrase catalytic
HMKEOBBI_01902 2.11e-69 - - - L - - - PFAM Integrase catalytic
HMKEOBBI_01903 1.41e-204 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
HMKEOBBI_01904 9.18e-104 - - - L - - - Transposase and inactivated derivatives IS30 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)