ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NMKGIHNB_00001 1.34e-96 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
NMKGIHNB_00003 3.92e-123 ywlG - - S - - - Belongs to the UPF0340 family
NMKGIHNB_00004 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NMKGIHNB_00005 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NMKGIHNB_00006 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NMKGIHNB_00008 6.92e-05 yebC - - M - - - Membrane
NMKGIHNB_00009 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NMKGIHNB_00010 3.87e-283 norN - - V - - - Mate efflux family protein
NMKGIHNB_00011 1.87e-76 asp - - S - - - cog cog1302
NMKGIHNB_00012 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NMKGIHNB_00013 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NMKGIHNB_00014 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NMKGIHNB_00015 7.09e-101 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NMKGIHNB_00016 1.73e-246 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMKGIHNB_00017 1.65e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMKGIHNB_00018 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMKGIHNB_00019 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMKGIHNB_00020 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMKGIHNB_00021 1.37e-91 - - - S - - - cog cog4699
NMKGIHNB_00022 3.65e-223 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMKGIHNB_00023 1.05e-178 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMKGIHNB_00024 1.1e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NMKGIHNB_00025 1.33e-89 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
NMKGIHNB_00026 4.31e-22 - - - NU - - - Type II secretory pathway pseudopilin
NMKGIHNB_00027 1.87e-92 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
NMKGIHNB_00028 3.67e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NMKGIHNB_00029 6.84e-226 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NMKGIHNB_00030 8.13e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMKGIHNB_00031 1.05e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NMKGIHNB_00032 3.1e-138 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NMKGIHNB_00034 5.02e-129 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NMKGIHNB_00035 2.36e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMKGIHNB_00036 1.51e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NMKGIHNB_00038 5.78e-72 ytpP - - CO - - - Thioredoxin
NMKGIHNB_00040 2.62e-145 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMKGIHNB_00041 7e-243 yeeE - - S ko:K07112 - ko00000 Sulphur transport
NMKGIHNB_00042 3.2e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
NMKGIHNB_00043 1.81e-85 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMKGIHNB_00044 1.99e-116 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMKGIHNB_00048 1.19e-199 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
NMKGIHNB_00049 1.2e-160 - - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant
NMKGIHNB_00050 3.08e-109 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMKGIHNB_00051 3.15e-279 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMKGIHNB_00052 1.91e-120 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMKGIHNB_00053 1.81e-149 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NMKGIHNB_00054 9.25e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NMKGIHNB_00055 2.32e-233 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NMKGIHNB_00056 2.09e-123 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NMKGIHNB_00057 3.14e-183 nirC_1 - - P - - - Formate nitrite transporter
NMKGIHNB_00058 1.47e-306 XK27_09615 - - C ko:K19784 - ko00000 reductase
NMKGIHNB_00059 3.33e-140 XK27_09620 - - S - - - FMN reductase (NADPH) activity
NMKGIHNB_00060 5.55e-100 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NMKGIHNB_00061 1.27e-98 - 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NMKGIHNB_00062 1.85e-285 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMKGIHNB_00063 2.05e-163 - - - S - - - Mitochondrial biogenesis AIM24
NMKGIHNB_00064 3.22e-114 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NMKGIHNB_00065 6.62e-66 - - - S - - - Protein of unknown function (DUF3397)
NMKGIHNB_00066 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMKGIHNB_00067 2.76e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMKGIHNB_00068 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NMKGIHNB_00069 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMKGIHNB_00070 2.66e-289 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 signal transduction protein with a C-terminal ATPase domain
NMKGIHNB_00071 1.09e-195 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00072 1.16e-260 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00073 2.95e-285 fasC - - T - - - protein histidine kinase activity
NMKGIHNB_00074 9.29e-168 fasA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
NMKGIHNB_00075 2.89e-293 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMKGIHNB_00076 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
NMKGIHNB_00077 2.38e-72 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMKGIHNB_00078 4.95e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMKGIHNB_00079 2.63e-224 jag - - S ko:K06346 - ko00000 RNA-binding protein
NMKGIHNB_00080 2.65e-126 - - - K - - - Transcriptional regulator
NMKGIHNB_00081 6.53e-127 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-quinone reductase (modulator of drug activity B)
NMKGIHNB_00082 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
NMKGIHNB_00083 3.18e-285 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMKGIHNB_00086 8.62e-66 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
NMKGIHNB_00087 2.49e-75 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
NMKGIHNB_00088 1.01e-182 - - - S - - - Macro domain protein
NMKGIHNB_00089 1.27e-66 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NMKGIHNB_00090 4.62e-92 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NMKGIHNB_00091 5.09e-180 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
NMKGIHNB_00092 1.49e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMKGIHNB_00093 6.29e-108 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMKGIHNB_00094 3.74e-65 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMKGIHNB_00096 1.99e-204 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMKGIHNB_00097 3.29e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NMKGIHNB_00098 1.52e-144 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NMKGIHNB_00099 2.68e-228 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
NMKGIHNB_00100 6.86e-228 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
NMKGIHNB_00101 7.91e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
NMKGIHNB_00102 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMKGIHNB_00103 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMKGIHNB_00104 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMKGIHNB_00105 5.21e-230 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
NMKGIHNB_00106 7.63e-156 - - - - - - - -
NMKGIHNB_00107 3.32e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NMKGIHNB_00108 4.38e-113 - - - S - - - Fusaric acid resistance protein-like
NMKGIHNB_00109 4e-82 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NMKGIHNB_00110 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NMKGIHNB_00111 4.18e-148 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
NMKGIHNB_00112 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMKGIHNB_00113 4.54e-45 ykzG - - S - - - Belongs to the UPF0356 family
NMKGIHNB_00114 3.81e-152 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
NMKGIHNB_00115 8.68e-95 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMKGIHNB_00116 2.72e-237 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMKGIHNB_00117 4.68e-144 XK27_12120 - - E - - - AzlC protein
NMKGIHNB_00118 1.14e-62 - - - S - - - branched-chain amino acid
NMKGIHNB_00119 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMKGIHNB_00120 6.48e-136 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMKGIHNB_00121 4.17e-196 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMKGIHNB_00122 1.18e-20 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMKGIHNB_00123 1.27e-116 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
NMKGIHNB_00124 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMKGIHNB_00125 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMKGIHNB_00127 3.23e-32 - - - - - - - -
NMKGIHNB_00129 6.87e-277 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NMKGIHNB_00131 1.88e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NMKGIHNB_00132 4.18e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMKGIHNB_00133 4.1e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMKGIHNB_00135 3.99e-157 XK27_01040 - - S - - - Protein of unknown function (DUF1129)
NMKGIHNB_00136 8.18e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
NMKGIHNB_00137 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NMKGIHNB_00141 2e-37 blpT - - - - - - -
NMKGIHNB_00142 3.14e-188 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
NMKGIHNB_00144 6.86e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
NMKGIHNB_00145 2.08e-110 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NMKGIHNB_00146 8.59e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMKGIHNB_00147 7.41e-80 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
NMKGIHNB_00148 1.09e-95 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMKGIHNB_00149 2.21e-228 scrR - - K ko:K03484 - ko00000,ko03000 Transcriptional regulator
NMKGIHNB_00150 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NMKGIHNB_00151 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_00152 1.08e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
NMKGIHNB_00153 2.42e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NMKGIHNB_00155 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMKGIHNB_00156 3.37e-250 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NMKGIHNB_00157 5.23e-249 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NMKGIHNB_00158 4.16e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMKGIHNB_00159 2.38e-253 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMKGIHNB_00160 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMKGIHNB_00164 4.07e-43 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NMKGIHNB_00166 1.55e-219 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMKGIHNB_00167 0.0 - - - S - - - hydrolases of the HAD superfamily
NMKGIHNB_00168 9.49e-170 yebC - - M - - - Membrane
NMKGIHNB_00169 0.0 - - - KT - - - response to antibiotic
NMKGIHNB_00170 1.26e-96 - - - K - - - LytTr DNA-binding domain
NMKGIHNB_00171 4.78e-153 - - - S - - - membrane
NMKGIHNB_00172 4.86e-98 mccF - - V - - - LD-carboxypeptidase
NMKGIHNB_00173 1.06e-57 - - - S - - - Sugar efflux transporter for intercellular exchange
NMKGIHNB_00174 4.86e-98 mccF - - V - - - LD-carboxypeptidase
NMKGIHNB_00175 1.06e-57 - - - S - - - Sugar efflux transporter for intercellular exchange
NMKGIHNB_00176 1.04e-245 mccF - - V - - - LD-carboxypeptidase
NMKGIHNB_00177 0.0 - - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 MreB/Mbl protein
NMKGIHNB_00179 8.38e-187 - - - V ko:K21397 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NMKGIHNB_00182 3.63e-15 - - - - - - - -
NMKGIHNB_00183 1.12e-286 dcuS 2.7.13.3 - T ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00184 9.5e-301 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00185 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NMKGIHNB_00186 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NMKGIHNB_00187 1.73e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NMKGIHNB_00188 2.59e-172 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00189 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NMKGIHNB_00190 2.37e-180 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMKGIHNB_00191 2.63e-284 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMKGIHNB_00192 1.37e-71 - - - S - - - Protein of unknown function (DUF805)
NMKGIHNB_00193 7.64e-19 - - - S - - - Protein of unknown function (DUF805)
NMKGIHNB_00194 1.95e-20 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
NMKGIHNB_00195 2.48e-113 - - - L - - - Endonuclease
NMKGIHNB_00196 3.36e-76 - - - J - - - Protein of unknown function (DUF805)
NMKGIHNB_00197 3.49e-59 - - - J - - - Protein of unknown function (DUF805)
NMKGIHNB_00200 8.18e-129 - - - - - - - -
NMKGIHNB_00201 2.67e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMKGIHNB_00202 5.32e-60 ftsL - - D - - - cell division protein FtsL
NMKGIHNB_00203 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
NMKGIHNB_00204 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMKGIHNB_00205 1.86e-302 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMKGIHNB_00208 7.06e-312 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMKGIHNB_00209 2.23e-117 yutD - - J - - - protein conserved in bacteria
NMKGIHNB_00210 7.84e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMKGIHNB_00211 1.51e-117 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
NMKGIHNB_00213 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00214 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00221 7.02e-59 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
NMKGIHNB_00222 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NMKGIHNB_00223 8.98e-193 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NMKGIHNB_00224 1.69e-119 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NMKGIHNB_00225 2.87e-174 cppA - - E - - - CppA N-terminal
NMKGIHNB_00226 4.2e-214 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
NMKGIHNB_00228 3.69e-95 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMKGIHNB_00229 1.01e-182 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
NMKGIHNB_00230 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
NMKGIHNB_00231 2.51e-257 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMKGIHNB_00233 6.65e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMKGIHNB_00234 7.25e-208 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00235 1.08e-166 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00236 3.64e-14 - - - S - - - Protein of unknown function (DUF4059)
NMKGIHNB_00237 1.32e-217 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMKGIHNB_00238 1.25e-135 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NMKGIHNB_00239 7.6e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMKGIHNB_00240 1.07e-240 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NMKGIHNB_00241 8.06e-232 ytqA - - S ko:K07139 - ko00000 radical SAM protein
NMKGIHNB_00242 3.95e-121 mraW1 - - J - - - (SAM)-dependent
NMKGIHNB_00244 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
NMKGIHNB_00245 7.29e-32 - - - - - - - -
NMKGIHNB_00247 1.68e-181 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00248 2.74e-302 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
NMKGIHNB_00250 4.91e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMKGIHNB_00252 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_00253 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_00254 6.2e-98 XK27_03180 - - T - - - universal stress protein
NMKGIHNB_00255 1.45e-300 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NMKGIHNB_00256 2.12e-180 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMKGIHNB_00257 3.39e-127 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
NMKGIHNB_00258 3.94e-189 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NMKGIHNB_00259 4.28e-120 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMKGIHNB_00260 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMKGIHNB_00261 3.03e-276 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
NMKGIHNB_00262 1.7e-202 - - - H - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NMKGIHNB_00263 4.03e-239 - - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMKGIHNB_00264 8.3e-291 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMKGIHNB_00265 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMKGIHNB_00266 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMKGIHNB_00267 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMKGIHNB_00268 7.18e-86 - - - - - - - -
NMKGIHNB_00269 4.9e-192 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMKGIHNB_00270 2.61e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NMKGIHNB_00271 4.61e-274 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMKGIHNB_00272 4.57e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NMKGIHNB_00273 7.52e-151 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMKGIHNB_00274 5.13e-138 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NMKGIHNB_00275 9.58e-112 yveA - - Q - - - Isochorismatase family
NMKGIHNB_00276 5.28e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMKGIHNB_00277 2.6e-178 XK27_06665 - - Q - - - Methyltransferase domain protein
NMKGIHNB_00278 5.45e-257 ylbM - - S - - - Belongs to the UPF0348 family
NMKGIHNB_00279 1.88e-52 yefM - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NMKGIHNB_00280 3.49e-57 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 Addiction module toxin, Txe YoeB family
NMKGIHNB_00281 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
NMKGIHNB_00282 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_00283 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_00284 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_00286 1.98e-133 - - - - - - - -
NMKGIHNB_00290 7.19e-94 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMKGIHNB_00291 8.31e-169 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00292 4.95e-222 XK27_05910 - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NMKGIHNB_00293 2.95e-197 ytmP - - M - - - Phosphotransferase
NMKGIHNB_00294 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMKGIHNB_00296 2.82e-281 ytfP - - S ko:K07007 - ko00000 Flavoprotein
NMKGIHNB_00297 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
NMKGIHNB_00298 1.09e-83 XK27_02560 - - S - - - cog cog2151
NMKGIHNB_00299 5.18e-76 WQ51_02910 - - S - - - Protein of unknown function, DUF536
NMKGIHNB_00300 1.26e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NMKGIHNB_00301 2.53e-161 - - - K - - - transcriptional regulator, MerR family
NMKGIHNB_00302 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00303 1.59e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00305 1.13e-43 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMKGIHNB_00306 2.85e-62 - - - - - - - -
NMKGIHNB_00308 6.89e-06 - - - - - - - -
NMKGIHNB_00309 0.0 - - - - - - - -
NMKGIHNB_00310 0.0 - 2.4.1.12 GT2 M ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
NMKGIHNB_00311 9.99e-216 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
NMKGIHNB_00312 1.57e-05 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
NMKGIHNB_00313 3.18e-216 - - - T - - - Diguanylate cyclase
NMKGIHNB_00314 1.18e-45 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NMKGIHNB_00315 2.63e-58 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
NMKGIHNB_00316 3.66e-35 - - - L - - - Transposase
NMKGIHNB_00317 4.11e-125 - - - L - - - Transposase
NMKGIHNB_00318 1.8e-58 - - - - - - - -
NMKGIHNB_00319 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NMKGIHNB_00320 1.87e-76 - - - - - - - -
NMKGIHNB_00321 1.47e-53 - 4.2.99.21 - E ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Chorismate mutase type II
NMKGIHNB_00322 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMKGIHNB_00323 5.83e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
NMKGIHNB_00324 6.07e-228 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMKGIHNB_00325 1.87e-171 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NMKGIHNB_00326 5.72e-124 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
NMKGIHNB_00327 1.22e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NMKGIHNB_00328 4.13e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NMKGIHNB_00331 2.58e-98 copY - - K - - - negative regulation of transcription, DNA-templated
NMKGIHNB_00332 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NMKGIHNB_00333 2.72e-42 copZ - - P - - - Heavy metal-associated domain protein
NMKGIHNB_00334 8.85e-244 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NMKGIHNB_00335 3.49e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00336 3.24e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00337 1.05e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00338 1.1e-198 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NMKGIHNB_00342 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMKGIHNB_00343 3.68e-152 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
NMKGIHNB_00345 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NMKGIHNB_00346 4.74e-252 yjbB - - G - - - Permeases of the major facilitator superfamily
NMKGIHNB_00347 6.62e-197 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
NMKGIHNB_00348 3.46e-124 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
NMKGIHNB_00349 7.5e-83 yjqA - - S - - - Bacterial PH domain
NMKGIHNB_00350 9.03e-202 corA - - P - - - CorA-like protein
NMKGIHNB_00351 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMKGIHNB_00353 2.9e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NMKGIHNB_00354 1.01e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
NMKGIHNB_00355 6.83e-198 nodB3 - - G - - - deacetylase
NMKGIHNB_00356 4.16e-182 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NMKGIHNB_00357 1.56e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NMKGIHNB_00358 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NMKGIHNB_00359 6.07e-292 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMKGIHNB_00360 8.01e-125 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
NMKGIHNB_00361 1.5e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
NMKGIHNB_00362 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NMKGIHNB_00363 2.48e-205 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
NMKGIHNB_00364 3.45e-111 ccl - - S - - - cog cog4708
NMKGIHNB_00365 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMKGIHNB_00366 1.06e-234 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMKGIHNB_00368 7.65e-226 yfjR - - K - - - regulation of single-species biofilm formation
NMKGIHNB_00370 2.17e-91 - - - S - - - QueT transporter
NMKGIHNB_00371 4.71e-200 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NMKGIHNB_00373 1.59e-242 XK27_00915 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMKGIHNB_00374 1.99e-15 yjdB - - S - - - Domain of unknown function (DUF4767)
NMKGIHNB_00375 5.55e-212 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
NMKGIHNB_00377 2.23e-226 - - - O - - - protein import
NMKGIHNB_00378 1.93e-159 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
NMKGIHNB_00379 2.65e-268 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00381 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NMKGIHNB_00382 3.71e-49 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
NMKGIHNB_00383 2.94e-299 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NMKGIHNB_00384 0.0 ydaO - - E - - - amino acid
NMKGIHNB_00385 4.02e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
NMKGIHNB_00386 1.01e-185 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMKGIHNB_00387 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NMKGIHNB_00388 4.82e-78 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMKGIHNB_00389 8.49e-100 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMKGIHNB_00390 1.47e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NMKGIHNB_00391 9.28e-271 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NMKGIHNB_00392 2.43e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
NMKGIHNB_00393 2.33e-167 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
NMKGIHNB_00394 4.32e-259 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
NMKGIHNB_00395 1.37e-195 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
NMKGIHNB_00396 1.37e-92 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
NMKGIHNB_00397 1.8e-195 - - - GK - - - ROK family
NMKGIHNB_00398 4.21e-266 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMKGIHNB_00399 5.2e-132 - - - M - - - Acetyltransferase (GNAT) domain
NMKGIHNB_00400 1.39e-276 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMKGIHNB_00401 1.1e-91 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
NMKGIHNB_00402 1.69e-77 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NMKGIHNB_00404 9.16e-74 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
NMKGIHNB_00405 1.31e-150 lrgB - - M - - - Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMKGIHNB_00406 1.2e-125 - - - S - - - IA, variant 1
NMKGIHNB_00407 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMKGIHNB_00408 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMKGIHNB_00409 5.41e-142 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
NMKGIHNB_00411 8.56e-193 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
NMKGIHNB_00413 7.34e-83 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
NMKGIHNB_00414 2.33e-81 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
NMKGIHNB_00415 4.89e-09 - - - O - - - ADP-ribosylglycohydrolase
NMKGIHNB_00416 4.24e-162 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NMKGIHNB_00417 9.86e-10 - - - S - - - Protein of unknown function (DUF4044)
NMKGIHNB_00418 3.8e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMKGIHNB_00419 5.23e-25 XK27_00735 - - - - - - -
NMKGIHNB_00420 4.83e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00421 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
NMKGIHNB_00422 1.15e-209 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NMKGIHNB_00424 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMKGIHNB_00425 1.34e-103 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
NMKGIHNB_00426 2.01e-178 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
NMKGIHNB_00427 7.02e-174 - - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMKGIHNB_00428 2.33e-261 arcT - - E - - - Aminotransferase
NMKGIHNB_00429 5.78e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMKGIHNB_00430 8.61e-28 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NMKGIHNB_00431 1.21e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMKGIHNB_00432 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMKGIHNB_00433 2.49e-256 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMKGIHNB_00434 1.43e-73 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
NMKGIHNB_00435 7.3e-216 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
NMKGIHNB_00436 0.0 - - - S - - - Glucosyl transferase GtrII
NMKGIHNB_00437 1.64e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMKGIHNB_00438 1.71e-284 - - - S - - - membrane protein involved in the export of O-antigen and teichoic acid
NMKGIHNB_00439 2.87e-200 - - - M - - - Glycosyltransferase, group 2 family protein
NMKGIHNB_00440 1.61e-226 - - - S - - - Glycosyltransferase like family 2
NMKGIHNB_00441 2.1e-163 arnC - - M ko:K00786 - ko00000,ko01000 group 2 family protein
NMKGIHNB_00442 1.68e-58 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
NMKGIHNB_00443 7.21e-191 - - - S - - - Glycosyltransferase group 2 family protein
NMKGIHNB_00444 1e-122 - - - S - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_00445 0.0 - - - M - - - Glycosyltransferase like family 2
NMKGIHNB_00446 1.91e-278 - - - M - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_00447 1.16e-282 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
NMKGIHNB_00448 1.92e-287 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
NMKGIHNB_00449 2.38e-223 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NMKGIHNB_00450 2.56e-180 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NMKGIHNB_00451 1.31e-285 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMKGIHNB_00452 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
NMKGIHNB_00453 4.43e-152 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NMKGIHNB_00454 5.47e-168 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
NMKGIHNB_00455 6.37e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMKGIHNB_00456 1.52e-79 XK27_04120 - - S - - - Putative amino acid metabolism
NMKGIHNB_00457 5.08e-261 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NMKGIHNB_00458 1.67e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMKGIHNB_00459 3.35e-131 yjbK - - S - - - Adenylate cyclase
NMKGIHNB_00460 2.36e-153 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
NMKGIHNB_00461 6.62e-195 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMKGIHNB_00462 6.05e-219 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NMKGIHNB_00463 1.25e-208 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NMKGIHNB_00464 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NMKGIHNB_00465 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NMKGIHNB_00466 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00467 4.05e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00468 3.83e-256 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMKGIHNB_00469 1.94e-216 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMKGIHNB_00470 6.13e-164 - - - V - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_00471 5.01e-160 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00472 8.13e-82 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
NMKGIHNB_00473 1.83e-187 - - - S - - - overlaps another CDS with the same product name
NMKGIHNB_00474 3.96e-186 XK27_02985 - - S - - - overlaps another CDS with the same product name
NMKGIHNB_00475 3.56e-269 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMKGIHNB_00476 4.34e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NMKGIHNB_00477 3.93e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
NMKGIHNB_00478 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMKGIHNB_00479 6.76e-218 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMKGIHNB_00480 6.27e-307 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMKGIHNB_00481 1.81e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NMKGIHNB_00482 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NMKGIHNB_00483 3.14e-137 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
NMKGIHNB_00484 1.42e-150 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Membrane
NMKGIHNB_00485 3.44e-219 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMKGIHNB_00486 5.45e-146 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMKGIHNB_00489 1.3e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMKGIHNB_00490 1.15e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NMKGIHNB_00491 7.5e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NMKGIHNB_00492 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NMKGIHNB_00493 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NMKGIHNB_00494 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMKGIHNB_00495 2.66e-252 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NMKGIHNB_00496 9.06e-243 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 glucose-1-phosphate adenylyltransferase
NMKGIHNB_00497 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NMKGIHNB_00498 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMKGIHNB_00499 1.13e-131 - - - K - - - Acetyltransferase GNAT Family
NMKGIHNB_00500 0.0 - - - S - - - Protein of unknown function (DUF3114)
NMKGIHNB_00502 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NMKGIHNB_00503 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00504 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00505 3.11e-83 XK27_10075 - - S - - - abc transporter atp-binding protein
NMKGIHNB_00506 1.3e-139 XK27_10075 - - S - - - ATPases associated with a variety of cellular activities
NMKGIHNB_00507 6.64e-11 - - - - - - - -
NMKGIHNB_00508 0.0 - - - M - - - domain protein
NMKGIHNB_00509 0.0 - - - M - - - Rib/alpha-like repeat
NMKGIHNB_00510 0.0 - - - M ko:K08643 - ko00000,ko01000,ko01002 signal peptide protein, YSIRK family
NMKGIHNB_00511 0.0 - - - GM - - - domain, Protein
NMKGIHNB_00512 5.23e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMKGIHNB_00513 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
NMKGIHNB_00514 0.0 - - - M - - - family 8
NMKGIHNB_00515 2.85e-268 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
NMKGIHNB_00516 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
NMKGIHNB_00517 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
NMKGIHNB_00518 2.01e-102 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
NMKGIHNB_00519 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMKGIHNB_00520 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMKGIHNB_00521 2.79e-310 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMKGIHNB_00522 3.27e-24 - - - S - - - Accessory secretory protein Sec Asp4
NMKGIHNB_00523 3.67e-23 - - - S - - - Accessory secretory protein Sec, Asp5
NMKGIHNB_00524 1.2e-238 - - - M - - - transferase activity, transferring glycosyl groups
NMKGIHNB_00525 3.63e-248 sraP - - UW ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 Hep Hag repeat protein
NMKGIHNB_00526 0.0 fliF 2.1.1.72 - N ko:K02409,ko:K02410,ko:K03427 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko01000,ko02035,ko02044,ko02048 bacterial-type flagellum-dependent cell motility
NMKGIHNB_00527 1.3e-91 sraP - - UW ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 Hep Hag repeat protein
NMKGIHNB_00528 0.0 - - - UW - - - domain, Protein
NMKGIHNB_00533 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
NMKGIHNB_00534 0.0 - 3.5.1.28 - M ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 domain protein
NMKGIHNB_00535 8.9e-167 - - - S - - - N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NMKGIHNB_00536 2.19e-125 maa 2.3.1.79 - GK ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NMKGIHNB_00537 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_00538 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_00539 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_00540 1.11e-82 - - - K - - - Transcriptional regulator, MarR family
NMKGIHNB_00541 1.06e-299 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
NMKGIHNB_00542 2.53e-163 - - - S - - - CAAX protease self-immunity
NMKGIHNB_00543 1.11e-151 mleR - - K - - - malolactic fermentation system
NMKGIHNB_00544 8.4e-64 - - - K - - - Helix-turn-helix
NMKGIHNB_00545 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NMKGIHNB_00546 1.38e-203 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NMKGIHNB_00547 3.73e-125 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMKGIHNB_00549 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
NMKGIHNB_00550 0.0 - - - S - - - dextransucrase activity
NMKGIHNB_00551 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
NMKGIHNB_00552 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
NMKGIHNB_00553 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
NMKGIHNB_00554 2.91e-200 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMKGIHNB_00555 2.16e-132 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMKGIHNB_00556 1.73e-17 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NMKGIHNB_00557 1.4e-222 - - - S - - - Domain of unknown function (DUF4297)
NMKGIHNB_00559 1.6e-302 - 2.7.7.7 - D ko:K02335,ko:K13582 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,ko04112,map00230,map00240,map01100,map03030,map03410,map03420,map03440,map04112 ko00000,ko00001,ko01000,ko03032,ko03400 nuclear chromosome segregation
NMKGIHNB_00560 0.0 - - - S - - - dextransucrase activity
NMKGIHNB_00562 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
NMKGIHNB_00563 1e-145 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NMKGIHNB_00564 1.21e-58 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NMKGIHNB_00565 5.44e-15 - - - S - - - integral membrane protein
NMKGIHNB_00568 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NMKGIHNB_00569 2.64e-46 - - - S - - - Immunity protein 41
NMKGIHNB_00570 3.76e-169 - - - T - - - Ser Thr phosphatase family protein
NMKGIHNB_00571 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
NMKGIHNB_00572 2.45e-287 - - - K - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_00573 9.69e-227 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
NMKGIHNB_00574 2.84e-123 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
NMKGIHNB_00575 3.46e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 dihydroxyacetone kinase, phosphotransfer subunit
NMKGIHNB_00576 2.82e-234 XK27_10475 - - S - - - oxidoreductase
NMKGIHNB_00577 1.13e-255 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 glycerol dehydrogenase
NMKGIHNB_00578 2.14e-06 - - - - - - - -
NMKGIHNB_00579 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
NMKGIHNB_00580 1.04e-271 vex1 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NMKGIHNB_00581 2.05e-139 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00582 3.01e-309 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NMKGIHNB_00583 2.13e-149 vncR - - K - - - Response regulator receiver domain protein
NMKGIHNB_00584 3.34e-287 vncS 2.7.13.3 - T ko:K10819 - ko00000,ko01000 Histidine kinase
NMKGIHNB_00585 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_00586 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_00587 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 COG0366 Glycosidases
NMKGIHNB_00588 1.1e-233 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NMKGIHNB_00589 1.64e-282 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMKGIHNB_00590 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
NMKGIHNB_00591 4.07e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NMKGIHNB_00592 4.88e-200 yvgN - - C - - - reductase
NMKGIHNB_00593 2.97e-41 XK27_10490 - - - - - - -
NMKGIHNB_00594 4.6e-53 - - - DJ ko:K06218 - ko00000,ko02048 nuclease activity
NMKGIHNB_00595 1.12e-145 - - - S - - - Protein of unknown function (DUF1275)
NMKGIHNB_00596 1.5e-141 yodC - - C - - - nitroreductase
NMKGIHNB_00597 1.69e-160 - - - T - - - Xre family transcriptional regulator
NMKGIHNB_00598 1.95e-191 - - - T - - - His Kinase A (phosphoacceptor) domain
NMKGIHNB_00599 9.55e-118 - - - S - - - Psort location Cytoplasmic, score
NMKGIHNB_00600 4.23e-166 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_00601 7.61e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00602 9.96e-287 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMKGIHNB_00603 7.72e-196 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
NMKGIHNB_00604 8.17e-98 ywnA_2 - - K - - - Transcriptional regulator
NMKGIHNB_00605 6.63e-191 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NMKGIHNB_00606 9.94e-142 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
NMKGIHNB_00607 4.96e-52 - - - - - - - -
NMKGIHNB_00608 6.89e-37 XK27_07105 - - K ko:K07729 - ko00000,ko03000 transcriptional
NMKGIHNB_00610 4.96e-218 ydhF - - S - - - Aldo keto reductase
NMKGIHNB_00611 5.34e-128 - - - K - - - WHG domain
NMKGIHNB_00612 4.13e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00613 4.17e-261 - - - P ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NMKGIHNB_00616 1.97e-56 - - - S - - - Sugar efflux transporter for intercellular exchange
NMKGIHNB_00617 5.84e-110 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NMKGIHNB_00618 0.0 - - - S - - - dextransucrase activity
NMKGIHNB_00619 2.72e-291 yfnA - - E ko:K03294 - ko00000 amino acid
NMKGIHNB_00620 3.43e-66 - - - P - - - Protein conserved in bacteria
NMKGIHNB_00621 4.17e-263 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
NMKGIHNB_00622 2.15e-27 csbD - - K - - - CsbD-like
NMKGIHNB_00623 1.04e-116 - - - S - - - Protein of unknown function (DUF421)
NMKGIHNB_00624 1.33e-83 - - - S - - - Protein of unknown function (DUF3290)
NMKGIHNB_00625 3.04e-231 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NMKGIHNB_00626 8.65e-294 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NMKGIHNB_00627 1.06e-228 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMKGIHNB_00629 3.29e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NMKGIHNB_00630 1.2e-283 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
NMKGIHNB_00631 1.25e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMKGIHNB_00632 3.54e-157 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMKGIHNB_00633 2.45e-204 - - - T - - - Histidine kinase
NMKGIHNB_00634 4.08e-169 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_00635 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NMKGIHNB_00636 1.17e-120 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
NMKGIHNB_00639 4.66e-200 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00640 4.12e-170 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
NMKGIHNB_00641 6.74e-106 - - - F - - - cytidine deaminase activity
NMKGIHNB_00642 1.3e-211 yocS - - S ko:K03453 - ko00000 Transporter
NMKGIHNB_00645 1.15e-202 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 'abc transporter, ATP-binding protein
NMKGIHNB_00646 4.81e-169 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NMKGIHNB_00647 1.62e-236 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMKGIHNB_00648 3.44e-133 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMKGIHNB_00649 1.01e-254 - - - S - - - Protein of unknown function DUF262
NMKGIHNB_00650 2.73e-146 - - - S - - - Protein of unknown function DUF262
NMKGIHNB_00651 7.19e-112 yfjR - - K - - - regulation of single-species biofilm formation
NMKGIHNB_00654 3.71e-236 - - - S ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NMKGIHNB_00655 7.33e-182 M1-956 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_00656 6.34e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_00657 4.84e-99 - - - K - - - Acetyltransferase (GNAT) domain
NMKGIHNB_00658 2.17e-60 - - - - - - - -
NMKGIHNB_00659 6.23e-183 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NMKGIHNB_00660 4.2e-137 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_00661 3.16e-195 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_00662 1.57e-192 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NMKGIHNB_00663 2.15e-106 - - - S - - - RDD family
NMKGIHNB_00664 9.76e-204 yjlA - - EG - - - membrane
NMKGIHNB_00665 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NMKGIHNB_00666 6.5e-189 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NMKGIHNB_00667 9.02e-154 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NMKGIHNB_00668 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMKGIHNB_00669 2.83e-261 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
NMKGIHNB_00670 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NMKGIHNB_00671 1.52e-134 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00672 2.63e-212 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
NMKGIHNB_00673 3.38e-172 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00674 4.34e-122 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMKGIHNB_00675 1.78e-83 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
NMKGIHNB_00676 1.09e-158 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
NMKGIHNB_00677 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMKGIHNB_00678 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMKGIHNB_00679 3.34e-111 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
NMKGIHNB_00680 0.0 clsA_1 - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMKGIHNB_00682 5.02e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMKGIHNB_00683 8.96e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMKGIHNB_00684 1.52e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMKGIHNB_00685 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NMKGIHNB_00686 2.37e-117 - - - S - - - Protein of unknown function (DUF3278)
NMKGIHNB_00687 3.9e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
NMKGIHNB_00688 7.97e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMKGIHNB_00689 2.92e-64 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMKGIHNB_00690 8.93e-46 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMKGIHNB_00691 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMKGIHNB_00693 3.78e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
NMKGIHNB_00694 5.26e-298 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMKGIHNB_00696 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_00697 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_00698 3.86e-108 - - - S - - - ECF-type riboflavin transporter, S component
NMKGIHNB_00699 1.26e-184 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
NMKGIHNB_00700 8.18e-102 - - - S - - - ECF-type riboflavin transporter, S component
NMKGIHNB_00701 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
NMKGIHNB_00702 0.0 noxE - - P - - - NADH oxidase
NMKGIHNB_00703 2.4e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NMKGIHNB_00704 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMKGIHNB_00705 6.26e-169 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
NMKGIHNB_00706 1.29e-94 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NMKGIHNB_00707 3e-206 ypuA - - S - - - secreted protein
NMKGIHNB_00708 3.92e-288 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
NMKGIHNB_00709 3.52e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
NMKGIHNB_00710 2.97e-216 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NMKGIHNB_00711 3.38e-224 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
NMKGIHNB_00712 2.07e-192 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
NMKGIHNB_00713 7.4e-230 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NMKGIHNB_00714 7.01e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NMKGIHNB_00715 7.92e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMKGIHNB_00716 1.74e-187 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMKGIHNB_00717 4.85e-131 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMKGIHNB_00718 7.36e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMKGIHNB_00719 2.13e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
NMKGIHNB_00720 1.19e-125 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
NMKGIHNB_00721 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00722 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00723 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMKGIHNB_00724 3.43e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
NMKGIHNB_00725 7.07e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMKGIHNB_00726 1.63e-297 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMKGIHNB_00727 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
NMKGIHNB_00728 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
NMKGIHNB_00730 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMKGIHNB_00731 2.97e-211 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
NMKGIHNB_00732 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NMKGIHNB_00733 1.24e-119 - - - S - - - ECF transporter, substrate-specific component
NMKGIHNB_00734 3.23e-115 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMKGIHNB_00735 5.13e-146 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
NMKGIHNB_00736 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NMKGIHNB_00737 2.39e-154 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMKGIHNB_00738 1.28e-302 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMKGIHNB_00739 4.36e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NMKGIHNB_00740 9.34e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NMKGIHNB_00741 4.38e-134 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
NMKGIHNB_00742 9.76e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NMKGIHNB_00743 2.03e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMKGIHNB_00744 5.8e-83 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMKGIHNB_00745 1.72e-245 - - - S ko:K07335 - ko00000 membrane
NMKGIHNB_00746 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_00747 2.12e-234 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMKGIHNB_00748 8.2e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMKGIHNB_00749 5.09e-154 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NMKGIHNB_00750 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NMKGIHNB_00751 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
NMKGIHNB_00752 6.82e-273 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NMKGIHNB_00753 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NMKGIHNB_00755 2.84e-252 pmrB - - EGP - - - Major Facilitator Superfamily
NMKGIHNB_00756 9.11e-84 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
NMKGIHNB_00757 4.52e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMKGIHNB_00758 4.76e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NMKGIHNB_00759 1.19e-170 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMKGIHNB_00760 5.6e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NMKGIHNB_00761 7.28e-314 - - - D - - - nuclear chromosome segregation
NMKGIHNB_00762 7.05e-172 yejC - - S - - - cyclic nucleotide-binding protein
NMKGIHNB_00763 4.03e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NMKGIHNB_00764 5.25e-233 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NMKGIHNB_00765 6.93e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NMKGIHNB_00766 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NMKGIHNB_00767 6.51e-181 XK27_10720 - - D - - - peptidase activity
NMKGIHNB_00768 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NMKGIHNB_00771 1.02e-215 yeiH - - S - - - Membrane
NMKGIHNB_00772 9.73e-165 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
NMKGIHNB_00773 5.13e-213 cpsY - - K - - - Transcriptional regulator
NMKGIHNB_00774 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMKGIHNB_00775 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_00776 7.1e-78 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
NMKGIHNB_00777 1.67e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00778 2.15e-145 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00779 9.8e-197 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NMKGIHNB_00780 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMKGIHNB_00781 3.4e-65 - - - - - - - -
NMKGIHNB_00782 2.42e-59 - - - - - - - -
NMKGIHNB_00783 2.33e-239 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NMKGIHNB_00784 9.52e-128 - - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMKGIHNB_00785 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NMKGIHNB_00786 1.75e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
NMKGIHNB_00787 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMKGIHNB_00788 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMKGIHNB_00789 1.33e-111 - - - - ko:K16788 - ko00000,ko02000 -
NMKGIHNB_00790 7.82e-118 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NMKGIHNB_00791 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
NMKGIHNB_00792 3.44e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMKGIHNB_00793 2.46e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMKGIHNB_00794 3.61e-215 - - - GK - - - ROK family
NMKGIHNB_00795 1.11e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NMKGIHNB_00796 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMKGIHNB_00797 3.16e-193 - - - S - - - TraX protein
NMKGIHNB_00798 1.77e-158 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NMKGIHNB_00799 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NMKGIHNB_00800 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMKGIHNB_00801 7.16e-281 XK27_05470 - - E - - - Methionine synthase
NMKGIHNB_00802 8.57e-93 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMKGIHNB_00803 1.04e-55 - - - P - - - Rhodanese-like protein
NMKGIHNB_00804 5.4e-175 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
NMKGIHNB_00806 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMKGIHNB_00807 5.56e-287 - - - L - - - Transposase
NMKGIHNB_00810 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NMKGIHNB_00811 7.74e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
NMKGIHNB_00812 1.57e-86 - - - K - - - Transcriptional regulator, MarR family
NMKGIHNB_00813 9.6e-169 - - - S - - - SnoaL-like polyketide cyclase
NMKGIHNB_00814 1.13e-191 - - - C - - - alcohol dehydrogenase
NMKGIHNB_00815 1.76e-157 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_00816 0.0 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMKGIHNB_00817 1.77e-170 - - - S - - - Phenazine biosynthesis protein
NMKGIHNB_00818 1.01e-125 - - - T ko:K16923 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NMKGIHNB_00819 3.58e-169 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NMKGIHNB_00820 1.63e-200 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase activity
NMKGIHNB_00821 2.82e-192 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_00822 5.77e-81 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NMKGIHNB_00823 1e-86 - - - K - - - Transcriptional regulator
NMKGIHNB_00824 2.27e-223 - - - C - - - nadph quinone reductase
NMKGIHNB_00825 1.51e-192 - - - I - - - Alpha/beta hydrolase family
NMKGIHNB_00826 2.56e-191 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMKGIHNB_00827 1.65e-49 - - - - - - - -
NMKGIHNB_00828 1.05e-76 - - - S - - - Protein of unknown function with HXXEE motif
NMKGIHNB_00829 5.43e-122 - - - K - - - Transcriptional regulator, TetR family
NMKGIHNB_00830 2.67e-197 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NMKGIHNB_00831 1.17e-247 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NMKGIHNB_00832 8.83e-155 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
NMKGIHNB_00833 3.32e-34 - - - L - - - PFAM Integrase catalytic region
NMKGIHNB_00834 1.83e-33 - - - L - - - PFAM Integrase catalytic region
NMKGIHNB_00835 7.96e-85 copY - - K - - - Copper transport repressor, CopY TcrY family
NMKGIHNB_00836 1.04e-83 - - - S - - - cog cog4633
NMKGIHNB_00837 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NMKGIHNB_00838 1.83e-182 - - - F - - - Phosphorylase superfamily
NMKGIHNB_00839 1.54e-140 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
NMKGIHNB_00840 0.0 - - - V - - - Type III restriction enzyme, res subunit
NMKGIHNB_00841 2.85e-61 - - - S - - - von Willebrand factor (vWF) type A domain
NMKGIHNB_00842 2.99e-222 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
NMKGIHNB_00843 6.12e-296 dinF - - V - - - Mate efflux family protein
NMKGIHNB_00844 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_00845 7.09e-222 - - - K - - - Helix-turn-helix XRE-family like proteins
NMKGIHNB_00849 0.0 yhaI - - L - - - Membrane
NMKGIHNB_00850 0.0 - - - S - - - secreted protein
NMKGIHNB_00851 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NMKGIHNB_00852 5.3e-172 - - - S - - - TraX protein
NMKGIHNB_00853 3.95e-121 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
NMKGIHNB_00854 1.33e-186 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMKGIHNB_00855 8.92e-222 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMKGIHNB_00856 3.52e-129 - - - - - - - -
NMKGIHNB_00857 3.4e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMKGIHNB_00858 3.05e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMKGIHNB_00859 4.05e-306 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NMKGIHNB_00860 1.13e-190 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NMKGIHNB_00861 4.41e-103 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00862 0.0 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMKGIHNB_00863 1.88e-216 bglC - - K - - - Transcriptional regulator
NMKGIHNB_00864 3.28e-312 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMKGIHNB_00865 1.12e-303 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
NMKGIHNB_00866 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NMKGIHNB_00867 3.44e-306 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
NMKGIHNB_00868 1.01e-173 - - - S - - - haloacid dehalogenase-like hydrolase
NMKGIHNB_00869 4.08e-112 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMKGIHNB_00870 1.91e-142 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
NMKGIHNB_00871 1.24e-47 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
NMKGIHNB_00872 2.14e-313 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
NMKGIHNB_00873 3.69e-189 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMKGIHNB_00874 7.03e-216 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NMKGIHNB_00875 3.58e-93 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMKGIHNB_00876 4.17e-60 yktA - - S - - - Belongs to the UPF0223 family
NMKGIHNB_00877 3.13e-182 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NMKGIHNB_00878 2.8e-312 rsmF - - J - - - NOL1 NOP2 sun family protein
NMKGIHNB_00879 3.28e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
NMKGIHNB_00880 1.55e-199 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NMKGIHNB_00881 1.24e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
NMKGIHNB_00882 7.48e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMKGIHNB_00883 2.49e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMKGIHNB_00884 1.33e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NMKGIHNB_00885 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NMKGIHNB_00886 1.03e-245 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NMKGIHNB_00887 4.88e-236 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NMKGIHNB_00889 1.3e-256 - - - L - - - Transposase
NMKGIHNB_00890 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMKGIHNB_00891 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NMKGIHNB_00892 1.3e-221 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NMKGIHNB_00893 4.11e-292 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMKGIHNB_00894 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00895 5.24e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00896 4.77e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMKGIHNB_00897 6.81e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
NMKGIHNB_00898 9.25e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMKGIHNB_00899 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NMKGIHNB_00900 5.6e-292 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
NMKGIHNB_00901 2.56e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NMKGIHNB_00902 0.0 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NMKGIHNB_00903 0.0 amiA 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-Acetylmuramoyl-L-alanine amidase
NMKGIHNB_00904 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
NMKGIHNB_00905 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NMKGIHNB_00906 7.55e-280 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMKGIHNB_00907 1.14e-231 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMKGIHNB_00908 2.06e-234 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NMKGIHNB_00909 1.36e-259 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00910 9.21e-287 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NMKGIHNB_00911 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_00912 4.18e-300 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMKGIHNB_00913 1.63e-153 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMKGIHNB_00914 1.31e-268 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMKGIHNB_00915 1.84e-314 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
NMKGIHNB_00916 1.19e-225 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
NMKGIHNB_00917 1.33e-194 - - - S - - - Phospholipase, patatin family
NMKGIHNB_00918 4.61e-127 - - - E - - - Lysophospholipase L1 and related esterases
NMKGIHNB_00919 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
NMKGIHNB_00920 3.9e-51 - - - S - - - granule-associated protein
NMKGIHNB_00921 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMKGIHNB_00922 6.25e-250 XK27_12525 - - S - - - hmm pf01594
NMKGIHNB_00923 5.53e-138 - - - G - - - Belongs to the phosphoglycerate mutase family
NMKGIHNB_00924 1.3e-138 - - - G - - - Belongs to the phosphoglycerate mutase family
NMKGIHNB_00925 1.16e-140 XK27_06100 - - G - - - Belongs to the phosphoglycerate mutase family
NMKGIHNB_00926 3.13e-32 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
NMKGIHNB_00927 2.27e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NMKGIHNB_00929 2.6e-237 - - - M - - - transferase activity, transferring glycosyl groups
NMKGIHNB_00930 1.52e-219 wefC - - M - - - Stealth protein CR2, conserved region 2
NMKGIHNB_00931 4.1e-274 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NMKGIHNB_00932 5.31e-205 - - - S - - - Acyltransferase family
NMKGIHNB_00933 4.68e-315 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NMKGIHNB_00934 2.37e-220 - - - - - - - -
NMKGIHNB_00935 1.54e-188 - - - M - - - Glycosyltransferase like family 2
NMKGIHNB_00936 4.36e-216 - - - M - - - Glycosyltransferase, group 2 family protein
NMKGIHNB_00937 6.94e-155 - - - M - - - Domain of unknown function (DUF1919)
NMKGIHNB_00938 7.61e-267 - - - M - - - Glycosyltransferase, group 1 family protein
NMKGIHNB_00939 2.33e-283 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
NMKGIHNB_00940 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NMKGIHNB_00941 1.29e-153 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
NMKGIHNB_00942 8.78e-144 capA - - M - - - biosynthesis protein
NMKGIHNB_00943 1.18e-168 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
NMKGIHNB_00944 0.0 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NMKGIHNB_00945 1.28e-164 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
NMKGIHNB_00946 3.54e-167 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
NMKGIHNB_00947 5.65e-202 clcA2 - - P - - - chloride
NMKGIHNB_00948 1.03e-62 - - - S ko:K03744 - ko00000 LemA family
NMKGIHNB_00949 9.78e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMKGIHNB_00950 2.55e-112 - - - S - - - Protein of unknown function (DUF1697)
NMKGIHNB_00951 4.3e-297 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMKGIHNB_00952 8e-154 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NMKGIHNB_00953 0.0 - - - V ko:K13732 ko05100,map05100 ko00000,ko00001 Glucan-binding protein C
NMKGIHNB_00954 0.0 - - - V - - - Glucan-binding protein C
NMKGIHNB_00955 2.46e-139 ung2 - - L - - - Uracil-DNA glycosylase
NMKGIHNB_00956 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
NMKGIHNB_00957 1.38e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NMKGIHNB_00958 1.69e-113 yybC - - - - - - -
NMKGIHNB_00959 9.88e-97 XK27_03610 - - K - - - Gnat family
NMKGIHNB_00960 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMKGIHNB_00961 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NMKGIHNB_00962 1.1e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMKGIHNB_00963 1.14e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NMKGIHNB_00964 6.6e-26 - - - M - - - LysM domain
NMKGIHNB_00965 2.86e-113 ebsA - - S - - - Family of unknown function (DUF5322)
NMKGIHNB_00966 8.58e-290 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NMKGIHNB_00967 0.0 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NMKGIHNB_00968 1.8e-123 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMKGIHNB_00969 5.94e-282 XK27_05225 - - G - - - COG0457 FOG TPR repeat
NMKGIHNB_00970 1.22e-231 XK27_05220 - - S - - - permease
NMKGIHNB_00971 3.39e-118 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMKGIHNB_00972 8.45e-211 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMKGIHNB_00973 1.04e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NMKGIHNB_00974 1.08e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMKGIHNB_00975 4.75e-267 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMKGIHNB_00976 2.57e-196 - - - S - - - Calcineurin-like phosphoesterase
NMKGIHNB_00977 2.03e-167 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NMKGIHNB_00978 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
NMKGIHNB_00979 3.41e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
NMKGIHNB_00980 1.63e-183 XK27_00115 - - K - - - Acetyltransferase GNAT family
NMKGIHNB_00981 1.89e-187 XK27_00835 - - S - - - hydrolases of the HAD superfamily
NMKGIHNB_00982 5.57e-289 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
NMKGIHNB_00983 4.46e-74 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
NMKGIHNB_00984 3.58e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
NMKGIHNB_00985 5.25e-313 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMKGIHNB_00986 4.13e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMKGIHNB_00987 1.1e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00988 3.51e-187 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMKGIHNB_00989 9.69e-158 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00990 5.84e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NMKGIHNB_00991 9.01e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_00992 2.27e-183 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMKGIHNB_00993 1.68e-158 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_00994 5.84e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NMKGIHNB_00995 5.21e-197 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NMKGIHNB_00996 3.37e-34 - - - S - - - DNA-directed RNA polymerase subunit beta
NMKGIHNB_00997 3.97e-294 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMKGIHNB_00999 7.06e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NMKGIHNB_01000 6.23e-167 - - - G - - - Domain of unknown function (DUF4832)
NMKGIHNB_01001 9.25e-108 - - - S - - - membrane
NMKGIHNB_01002 2.09e-123 - - - P - - - VTC domain
NMKGIHNB_01003 5.95e-280 - - - M ko:K06330 - ko00000 CotH kinase protein
NMKGIHNB_01004 1.09e-242 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
NMKGIHNB_01005 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
NMKGIHNB_01006 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
NMKGIHNB_01007 8e-186 - - - - - - - -
NMKGIHNB_01008 0.0 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
NMKGIHNB_01009 1.48e-269 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMKGIHNB_01010 1.8e-218 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMKGIHNB_01011 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMKGIHNB_01012 2.08e-112 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NMKGIHNB_01013 3.84e-204 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMKGIHNB_01014 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NMKGIHNB_01017 2.33e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMKGIHNB_01018 4.54e-267 eriC - - P ko:K03281 - ko00000 Chloride transporter ClC family
NMKGIHNB_01019 9.78e-52 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
NMKGIHNB_01020 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
NMKGIHNB_01021 3.48e-98 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NMKGIHNB_01022 2.52e-26 XK27_08880 - - - - - - -
NMKGIHNB_01023 3.12e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
NMKGIHNB_01024 2.94e-191 estA - CE1 S ko:K03930 - ko00000,ko01000 Esterase
NMKGIHNB_01025 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMKGIHNB_01026 3.8e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01027 1.37e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMKGIHNB_01028 1.38e-228 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
NMKGIHNB_01030 0.0 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_01031 0.0 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_01032 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NMKGIHNB_01033 3.31e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMKGIHNB_01034 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NMKGIHNB_01035 1.6e-145 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMKGIHNB_01036 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMKGIHNB_01037 2.25e-240 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMKGIHNB_01038 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMKGIHNB_01039 6.94e-71 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMKGIHNB_01040 4.64e-92 - - - S ko:K06893 - ko00000 SnoaL-like polyketide cyclase
NMKGIHNB_01041 6.88e-71 hxlR - - K - - - HxlR-like helix-turn-helix
NMKGIHNB_01042 2.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMKGIHNB_01043 2.05e-228 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
NMKGIHNB_01045 3.1e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMKGIHNB_01046 2.53e-121 ypmS - - S - - - Protein conserved in bacteria
NMKGIHNB_01047 3.42e-201 XK27_03630 - - E - - - COG2755 Lysophospholipase L1 and related esterases
NMKGIHNB_01048 8.55e-185 WQ51_01275 - - S - - - DegV family
NMKGIHNB_01049 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NMKGIHNB_01050 1.26e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NMKGIHNB_01051 1.89e-190 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NMKGIHNB_01052 4.5e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NMKGIHNB_01053 2.44e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMKGIHNB_01054 2.84e-293 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMKGIHNB_01056 5.28e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMKGIHNB_01057 1.82e-162 dnaD - - - ko:K02086 - ko00000 -
NMKGIHNB_01058 9.41e-231 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMKGIHNB_01059 4.35e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMKGIHNB_01060 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
NMKGIHNB_01061 5.13e-87 GnaT 2.5.1.16 - K ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferase
NMKGIHNB_01062 1.44e-25 - - - Q - - - Methyltransferase domain
NMKGIHNB_01063 1.43e-175 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMKGIHNB_01064 2.57e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMKGIHNB_01065 4.84e-144 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
NMKGIHNB_01066 5.26e-284 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMKGIHNB_01067 9.41e-279 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_01068 4.6e-308 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NMKGIHNB_01069 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
NMKGIHNB_01070 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
NMKGIHNB_01071 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
NMKGIHNB_01072 5e-230 - - - M - - - glycosyl transferase family 2
NMKGIHNB_01073 1.88e-167 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
NMKGIHNB_01074 1.14e-183 - - - P - - - molecular chaperone
NMKGIHNB_01075 3.45e-131 XK27_05505 - - S - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_01077 1.27e-66 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NMKGIHNB_01078 4.08e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NMKGIHNB_01079 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMKGIHNB_01080 3.25e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMKGIHNB_01081 5.74e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMKGIHNB_01082 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NMKGIHNB_01083 1.02e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMKGIHNB_01084 3.42e-150 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMKGIHNB_01085 2.92e-231 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMKGIHNB_01086 2.01e-245 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMKGIHNB_01087 9.02e-77 XK27_08085 - - - - - - -
NMKGIHNB_01088 4.59e-198 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
NMKGIHNB_01089 1.39e-173 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
NMKGIHNB_01090 1.51e-152 - - - S - - - tigr01906
NMKGIHNB_01091 8.64e-178 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMKGIHNB_01092 4.33e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NMKGIHNB_01093 6.06e-273 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NMKGIHNB_01096 7.79e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMKGIHNB_01097 1.86e-140 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NMKGIHNB_01098 7.83e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMKGIHNB_01099 0.0 - - - S - - - phospholipase Carboxylesterase
NMKGIHNB_01100 1.66e-246 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
NMKGIHNB_01101 4.22e-183 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
NMKGIHNB_01102 4.82e-182 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMKGIHNB_01103 3.96e-155 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NMKGIHNB_01104 1.29e-86 mesH - - S - - - GtrA-like protein
NMKGIHNB_01105 2.77e-316 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMKGIHNB_01106 3.03e-210 ybbR - - S - - - Protein conserved in bacteria
NMKGIHNB_01107 1.17e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMKGIHNB_01108 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
NMKGIHNB_01109 2.32e-189 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NMKGIHNB_01110 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMKGIHNB_01111 1.28e-170 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
NMKGIHNB_01113 3.08e-52 - - - S - - - yiaA/B two helix domain
NMKGIHNB_01114 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
NMKGIHNB_01115 5.27e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NMKGIHNB_01116 1.58e-227 yfmL - - L - - - DEAD DEAH box helicase
NMKGIHNB_01117 1.16e-286 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
NMKGIHNB_01118 1.78e-194 XK27_05675 - - S - - - Esterase
NMKGIHNB_01119 7.56e-206 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
NMKGIHNB_01120 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NMKGIHNB_01121 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMKGIHNB_01122 2.72e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
NMKGIHNB_01123 1.34e-278 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
NMKGIHNB_01124 2.26e-266 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NMKGIHNB_01125 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMKGIHNB_01126 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NMKGIHNB_01127 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMKGIHNB_01128 4.51e-236 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMKGIHNB_01129 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMKGIHNB_01130 3.37e-192 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NMKGIHNB_01131 3.76e-177 ylmH - - S - - - conserved protein, contains S4-like domain
NMKGIHNB_01132 1.95e-41 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
NMKGIHNB_01133 1.46e-121 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
NMKGIHNB_01134 1.05e-154 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMKGIHNB_01135 2.82e-298 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMKGIHNB_01136 5.77e-291 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMKGIHNB_01137 2.01e-190 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMKGIHNB_01138 5.01e-254 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMKGIHNB_01139 1.29e-315 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMKGIHNB_01140 3.66e-12 - - - S - - - Protein of unknown function (DUF3165)
NMKGIHNB_01141 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NMKGIHNB_01142 1.88e-225 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NMKGIHNB_01143 4.13e-38 yqgQ - - S - - - protein conserved in bacteria
NMKGIHNB_01144 1.35e-101 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NMKGIHNB_01145 2.93e-114 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NMKGIHNB_01146 6.13e-129 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NMKGIHNB_01147 2.92e-208 - - - V - - - D-alanyl-D-alanine carboxypeptidase
NMKGIHNB_01148 9.19e-143 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NMKGIHNB_01149 2.2e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NMKGIHNB_01150 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NMKGIHNB_01151 2.67e-83 - - - S - - - Domain of unknown function (DUF4430)
NMKGIHNB_01152 2.88e-95 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NMKGIHNB_01153 9.65e-163 sitB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_01154 2.89e-171 mtsC - - P ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type Mn2 Zn2 transport systems, permease components
NMKGIHNB_01155 3.23e-219 psaA - - P ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NMKGIHNB_01156 1.1e-150 sirR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NMKGIHNB_01157 3.3e-187 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NMKGIHNB_01158 3.61e-119 lemA - - S ko:K03744 - ko00000 LemA family
NMKGIHNB_01159 1.56e-232 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NMKGIHNB_01160 0.0 - - - M - - - Right handed beta helix region
NMKGIHNB_01161 9.18e-184 - - - S - - - PD-(D/E)XK nuclease family transposase
NMKGIHNB_01162 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NMKGIHNB_01163 6.53e-66 - - - S - - - Nucleotide pyrophosphohydrolase
NMKGIHNB_01164 2.11e-172 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMKGIHNB_01165 1.37e-252 - - - S - - - Protein of unknown function (DUF2974)
NMKGIHNB_01166 4.02e-145 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMKGIHNB_01167 5.24e-195 hmpP2 - - G - - - hydrolase
NMKGIHNB_01168 2.29e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
NMKGIHNB_01169 5.34e-192 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
NMKGIHNB_01170 5.87e-104 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMKGIHNB_01171 1.2e-148 pgm - - G - - - Phosphoglycerate mutase
NMKGIHNB_01173 6.57e-224 - - - S ko:K07025 - ko00000 hydrolase
NMKGIHNB_01174 1.73e-36 - - - - - - - -
NMKGIHNB_01175 1.56e-215 - - - M - - - LysM domain
NMKGIHNB_01176 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NMKGIHNB_01178 2.54e-19 - - - - - - - -
NMKGIHNB_01179 1.89e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NMKGIHNB_01180 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
NMKGIHNB_01182 1.04e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
NMKGIHNB_01183 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NMKGIHNB_01184 1.75e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NMKGIHNB_01186 1.86e-88 ytxH - - S - - - General stress protein
NMKGIHNB_01187 2e-27 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMKGIHNB_01188 2.92e-188 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMKGIHNB_01189 2.53e-212 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMKGIHNB_01190 1.02e-55 WQ51_05770 - - KT - - - PspC domain
NMKGIHNB_01191 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_01192 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_01193 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_01194 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
NMKGIHNB_01196 9.34e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
NMKGIHNB_01197 2.8e-190 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
NMKGIHNB_01198 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 Sulfate permease and related transporters (MFS superfamily)
NMKGIHNB_01199 9.8e-135 - - - - - - - -
NMKGIHNB_01200 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase
NMKGIHNB_01201 3.49e-123 - - - S - - - CAAX protease self-immunity
NMKGIHNB_01202 4.36e-67 - - - - - - - -
NMKGIHNB_01204 2.03e-84 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
NMKGIHNB_01205 2.29e-79 - - - S - - - Protein of unknown function (DUF1722)
NMKGIHNB_01206 1.93e-31 - - - M - - - Bacterial lipoprotein
NMKGIHNB_01208 1.81e-164 - - - V - - - CAAX protease self-immunity
NMKGIHNB_01209 2.67e-63 - - - - - - - -
NMKGIHNB_01210 1.35e-95 - - - K - - - TetR family transcriptional regulator
NMKGIHNB_01211 9.38e-104 - - - Q - - - Methyltransferase domain
NMKGIHNB_01212 7.6e-180 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMKGIHNB_01213 5.3e-222 acoB - - C ko:K21417 - ko00000,ko01000 dehydrogenase E1 component
NMKGIHNB_01214 2.5e-211 acoA - - C ko:K21416 - ko00000,ko01000 Acetoin dehydrogenase E1 component subunit alpha
NMKGIHNB_01215 6.2e-215 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NMKGIHNB_01216 2.27e-32 - - - K - - - CsbD-like
NMKGIHNB_01217 7.79e-25 - - - K - - - CsbD-like
NMKGIHNB_01218 5.37e-94 - - - S - - - Asp23 family, cell envelope-related function
NMKGIHNB_01219 1.78e-31 - - - S - - - Small integral membrane protein
NMKGIHNB_01220 1.45e-116 - - - - - - - -
NMKGIHNB_01221 2.58e-41 - - - S - - - Transglycosylase associated protein
NMKGIHNB_01223 1e-218 - - - S - - - Domain of unknown function (DUF389)
NMKGIHNB_01224 1.05e-196 yegS - - I - - - Diacylglycerol kinase
NMKGIHNB_01225 1.54e-158 - - - S - - - Putative esterase
NMKGIHNB_01226 7.41e-231 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NMKGIHNB_01227 1.95e-171 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NMKGIHNB_01228 1.05e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMKGIHNB_01229 2.23e-158 - - - V - - - CAAX protease self-immunity
NMKGIHNB_01230 7.71e-192 - - - S - - - Domain of unknown function (DUF4300)
NMKGIHNB_01231 8.33e-122 tetR - - K - - - transcriptional regulator
NMKGIHNB_01232 0.0 - - - P - - - Major facilitator superfamily
NMKGIHNB_01233 1.9e-19 yjdB - - S - - - Domain of unknown function (DUF4767)
NMKGIHNB_01235 6.34e-139 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NMKGIHNB_01236 1.07e-166 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
NMKGIHNB_01237 1.92e-120 yagB - - F ko:K06950 - ko00000 HD superfamily hydrolase
NMKGIHNB_01238 5.71e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NMKGIHNB_01239 6.12e-194 ChZ00x2 - - S - - - EDD domain protein, DegV family
NMKGIHNB_01240 3.98e-259 yycB - - P ko:K03449 - ko00000,ko02000 transporter
NMKGIHNB_01241 3.9e-170 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMKGIHNB_01242 6.11e-148 - - - - - - - -
NMKGIHNB_01243 2.81e-250 - - - - - - - -
NMKGIHNB_01244 3.38e-165 yceE - - Q - - - phosphatase activity
NMKGIHNB_01245 8.61e-90 - - - K - - - helix_turn _helix lactose operon repressor
NMKGIHNB_01246 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_01247 5.4e-99 ccpB - - K - - - helix_turn _helix lactose operon repressor
NMKGIHNB_01248 5.79e-126 - - - - - - - -
NMKGIHNB_01249 1.01e-116 - - - K - - - Acetyltransferase (GNAT) domain
NMKGIHNB_01250 7.14e-193 - - - K ko:K13653 - ko00000,ko03000 Integron-associated effector binding protein
NMKGIHNB_01251 3.82e-91 - - - E - - - cog cog0346
NMKGIHNB_01252 7.55e-69 - - - K - - - TfoX N-terminal domain
NMKGIHNB_01253 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMKGIHNB_01254 1.28e-126 mip - - S - - - hydroperoxide reductase activity
NMKGIHNB_01255 2.9e-252 - - - I - - - acyl-CoA dehydrogenase
NMKGIHNB_01256 2.25e-196 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
NMKGIHNB_01257 0.0 msrR - - K - - - Transcriptional regulator
NMKGIHNB_01258 2.42e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NMKGIHNB_01259 7.63e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMKGIHNB_01260 1.7e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMKGIHNB_01261 6.6e-207 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NMKGIHNB_01262 2.99e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
NMKGIHNB_01263 2.15e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NMKGIHNB_01264 1.5e-278 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMKGIHNB_01265 5.89e-257 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMKGIHNB_01266 1.14e-196 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMKGIHNB_01267 2.89e-151 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMKGIHNB_01268 1.28e-274 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NMKGIHNB_01269 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NMKGIHNB_01270 4.48e-34 WQ51_00785 - - - - - - -
NMKGIHNB_01271 6.13e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMKGIHNB_01272 1.46e-101 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NMKGIHNB_01273 2.73e-245 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NMKGIHNB_01274 1.25e-242 XK27_07735 - - S - - - YjbR
NMKGIHNB_01275 3.69e-233 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
NMKGIHNB_01276 1.47e-246 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
NMKGIHNB_01277 1.17e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
NMKGIHNB_01278 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMKGIHNB_01279 1.98e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NMKGIHNB_01280 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMKGIHNB_01281 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NMKGIHNB_01282 2.52e-282 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
NMKGIHNB_01283 7.94e-117 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMKGIHNB_01284 6.33e-188 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMKGIHNB_01285 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMKGIHNB_01286 8.52e-86 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NMKGIHNB_01287 6.25e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMKGIHNB_01288 8.21e-185 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
NMKGIHNB_01289 1.85e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMKGIHNB_01290 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
NMKGIHNB_01291 7.33e-185 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMKGIHNB_01292 2.73e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMKGIHNB_01293 1.7e-189 - - - I - - - Alpha/beta hydrolase family
NMKGIHNB_01294 2.42e-12 - - - - - - - -
NMKGIHNB_01295 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NMKGIHNB_01296 4.11e-100 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
NMKGIHNB_01297 7.38e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01298 1.27e-150 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMKGIHNB_01299 3.31e-47 ykuJ - - S - - - protein conserved in bacteria
NMKGIHNB_01300 1.97e-229 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMKGIHNB_01301 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NMKGIHNB_01302 2.16e-108 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NMKGIHNB_01303 2.23e-65 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NMKGIHNB_01304 3.49e-220 - - - S - - - oxidoreductase
NMKGIHNB_01305 5.57e-288 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
NMKGIHNB_01306 1.32e-148 - - - M - - - Pfam SNARE associated Golgi protein
NMKGIHNB_01307 5.05e-138 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
NMKGIHNB_01310 7.8e-267 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
NMKGIHNB_01313 3.6e-24 - - - S - - - Protein of unknown function (DUF2969)
NMKGIHNB_01314 1.68e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NMKGIHNB_01315 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMKGIHNB_01318 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMKGIHNB_01319 1.81e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMKGIHNB_01320 4.35e-19 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
NMKGIHNB_01321 3.14e-42 - - - S - - - Domain of unknown function (DUF1912)
NMKGIHNB_01322 4.42e-221 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
NMKGIHNB_01323 0.0 lysP - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NMKGIHNB_01324 9.58e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NMKGIHNB_01325 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMKGIHNB_01326 2.97e-30 - - - - - - - -
NMKGIHNB_01327 7.88e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMKGIHNB_01328 9.98e-212 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMKGIHNB_01329 2.56e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
NMKGIHNB_01330 1.93e-285 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NMKGIHNB_01331 1.08e-102 - - - K - - - hmm pf08876
NMKGIHNB_01332 7.1e-152 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NMKGIHNB_01333 1.64e-39 pspC - - KT - - - PspC domain protein
NMKGIHNB_01334 4.97e-37 - - - K - - - regulation of RNA biosynthetic process
NMKGIHNB_01335 3.8e-161 - - - S - - - Belongs to the UPF0255 family
NMKGIHNB_01336 1.95e-249 - - - S - - - Protein of unknown function (DUF3114)
NMKGIHNB_01337 8.05e-189 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMKGIHNB_01338 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMKGIHNB_01340 3.83e-312 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NMKGIHNB_01341 1.72e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NMKGIHNB_01342 0.0 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
NMKGIHNB_01343 7.33e-152 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMKGIHNB_01344 2.18e-43 - - - - - - - -
NMKGIHNB_01345 2.78e-121 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
NMKGIHNB_01346 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMKGIHNB_01347 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NMKGIHNB_01348 1.7e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMKGIHNB_01349 1.02e-213 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NMKGIHNB_01350 1.72e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NMKGIHNB_01351 2.35e-188 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NMKGIHNB_01352 2.09e-315 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMKGIHNB_01353 2.46e-225 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NMKGIHNB_01354 9.57e-141 - - - T - - - Response regulator receiver domain protein
NMKGIHNB_01355 1.55e-65 ykoJ - - S - - - membrane
NMKGIHNB_01356 8.73e-152 - - - E - - - alpha/beta hydrolase fold
NMKGIHNB_01358 1.37e-249 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NMKGIHNB_01359 2.56e-271 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMKGIHNB_01360 3.08e-162 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NMKGIHNB_01361 5.36e-148 - - - S - - - VIT family
NMKGIHNB_01362 7.67e-176 - - - F - - - Phosphorylase superfamily
NMKGIHNB_01364 7.18e-39 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
NMKGIHNB_01365 8.26e-252 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NMKGIHNB_01366 1.95e-63 - - - S - - - Protein conserved in bacteria
NMKGIHNB_01367 1.09e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMKGIHNB_01368 3.38e-252 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMKGIHNB_01369 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01370 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01371 3.21e-23 - - - K ko:K02051 - ko00000,ko00002,ko02000 DNA-binding transcription factor activity
NMKGIHNB_01372 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NMKGIHNB_01373 2.14e-133 - - - K - - - Transcriptional regulator, AbiEi antitoxin
NMKGIHNB_01374 3.92e-36 XK27_00530 - - M - - - CHAP domain protein
NMKGIHNB_01375 1.62e-28 - - - S ko:K19165 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NMKGIHNB_01377 9.69e-170 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
NMKGIHNB_01378 8.04e-294 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NMKGIHNB_01379 6.14e-60 - - - L - - - COG3547 Transposase and inactivated derivatives
NMKGIHNB_01380 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NMKGIHNB_01382 0.0 - - - NU - - - GBS Bsp-like repeat
NMKGIHNB_01383 1.97e-45 - - - L - - - Transposase IS116 IS110 IS902
NMKGIHNB_01384 4.36e-187 - - - L - - - COG3547 Transposase and inactivated derivatives
NMKGIHNB_01386 2.03e-224 - 2.5.1.30, 2.5.1.90 - H ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 isoprenoid biosynthetic process
NMKGIHNB_01387 5.97e-210 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NMKGIHNB_01388 8.38e-163 - 2.7.1.176 - O ko:K16214 - ko00000,ko01000,ko02048 Zeta toxin
NMKGIHNB_01389 1.27e-105 - - - K ko:K18830 - ko00000,ko02048,ko03000 Cro/C1-type HTH DNA-binding domain
NMKGIHNB_01390 4.33e-58 XK27_00545 - - U - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NMKGIHNB_01391 1.29e-83 - - - P - - - arsenate reductase (glutaredoxin) activity
NMKGIHNB_01392 1.7e-79 - - - - - - - -
NMKGIHNB_01394 7.54e-61 - - - L - - - Transposase
NMKGIHNB_01395 5.99e-34 - - - L - - - COG3547 Transposase and inactivated derivatives
NMKGIHNB_01397 2.4e-05 - - - K - - - Psort location Cytoplasmic, score 8.87
NMKGIHNB_01398 2.15e-09 - - - S - - - sequence-specific DNA binding
NMKGIHNB_01400 4.54e-52 - - - L - - - transposase IS116 IS110 IS902 family
NMKGIHNB_01401 1.51e-132 salR - - K ko:K14989 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NMKGIHNB_01402 7.99e-316 - - - T ko:K14988 ko02020,map02020 ko00000,ko00001,ko00002,ko01001,ko02022 Histidine kinase
NMKGIHNB_01403 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NMKGIHNB_01404 1.07e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NMKGIHNB_01405 0.0 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMKGIHNB_01406 0.0 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
NMKGIHNB_01408 0.0 XK27_00500 - - L - - - the current gene model (or a revised gene model) may contain a
NMKGIHNB_01411 4.88e-66 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_01413 1.47e-46 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMKGIHNB_01414 1.46e-18 - - - - - - - -
NMKGIHNB_01415 3.15e-93 - - - S - - - Region found in RelA / SpoT proteins
NMKGIHNB_01417 5.98e-26 - - - D ko:K03496 - ko00000,ko03036,ko04812 Cellulose biosynthesis protein BcsQ
NMKGIHNB_01420 2.13e-22 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
NMKGIHNB_01421 1.64e-62 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NMKGIHNB_01422 4.64e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
NMKGIHNB_01423 2.67e-291 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NMKGIHNB_01424 6.59e-315 - - - NU - - - GBS Bsp-like repeat
NMKGIHNB_01425 3.8e-17 - - - - - - - -
NMKGIHNB_01427 3.24e-21 - - - S - - - Ribosomal protein S1-like RNA-binding domain
NMKGIHNB_01429 2.14e-147 - - - U - - - TraM recognition site of TraD and TraG
NMKGIHNB_01436 5.36e-227 - - - S - - - there are four paralogs in L.lactis
NMKGIHNB_01437 1.03e-57 - - - - - - - -
NMKGIHNB_01438 3.28e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_01439 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_01441 1.27e-126 - - - - - - - -
NMKGIHNB_01444 6.91e-43 - - - S - - - Single-strand binding protein family
NMKGIHNB_01445 1.71e-82 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NMKGIHNB_01457 1.07e-134 - - - K - - - Transcriptional regulator, AbiEi antitoxin
NMKGIHNB_01458 5.37e-21 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
NMKGIHNB_01459 7.29e-92 - - - - - - - -
NMKGIHNB_01460 6.23e-128 - - - - - - - -
NMKGIHNB_01461 3.59e-102 - - - F - - - Belongs to the Nudix hydrolase family
NMKGIHNB_01462 1.22e-102 - - - P - - - Protein conserved in bacteria
NMKGIHNB_01465 4.34e-249 scnK - - T - - - Histidine kinase
NMKGIHNB_01466 3.02e-161 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMKGIHNB_01467 8.56e-14 - - - S - - - Type-A lantibiotic
NMKGIHNB_01468 8.56e-14 - - - S - - - Type-A lantibiotic
NMKGIHNB_01470 0.0 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
NMKGIHNB_01471 0.0 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMKGIHNB_01472 4.39e-214 bcrA - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01473 6.54e-168 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_01474 1.03e-158 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_01475 5.69e-12 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMKGIHNB_01476 2.98e-41 - - - K - - - Helix-turn-helix XRE-family like proteins
NMKGIHNB_01477 1.31e-67 - - - S - - - Toxin-antitoxin system, toxin component, RelE family
NMKGIHNB_01479 1.13e-98 - - - S - - - ASCH
NMKGIHNB_01481 3.52e-06 - - - V - - - Psort location Cytoplasmic, score
NMKGIHNB_01486 8.56e-157 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NMKGIHNB_01488 5.12e-54 - - - - - - - -
NMKGIHNB_01490 2.49e-34 - - - - - - - -
NMKGIHNB_01491 3.85e-127 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NMKGIHNB_01492 8.58e-212 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NMKGIHNB_01494 0.0 - - - V ko:K06147,ko:K18893,ko:K20483 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko02000 (ABC) transporter
NMKGIHNB_01495 7.06e-150 srtF - - V ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NMKGIHNB_01496 3.11e-128 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_01497 2.92e-110 - - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMKGIHNB_01500 3.42e-135 - - - U - - - AAA-like domain
NMKGIHNB_01504 6.34e-48 - - - L - - - viral genome integration into host DNA
NMKGIHNB_01506 8.26e-41 - - - - - - - -
NMKGIHNB_01507 8.28e-68 - - - - - - - -
NMKGIHNB_01508 1.38e-45 - - - M - - - CHAP domain protein
NMKGIHNB_01510 6.65e-52 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
NMKGIHNB_01511 4.56e-75 - - - V - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_01512 2.16e-132 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01513 1.07e-77 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
NMKGIHNB_01514 7.41e-97 mutT1 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Nudix family
NMKGIHNB_01515 3.04e-56 - - - - - - - -
NMKGIHNB_01516 1.07e-186 - - - L - - - transposase IS116 IS110 IS902 family
NMKGIHNB_01517 4.2e-11 - - - K ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NMKGIHNB_01518 1.67e-52 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMKGIHNB_01520 3.73e-73 - - - F - - - Thymidylate synthase
NMKGIHNB_01521 0.000195 - 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMKGIHNB_01526 1.21e-15 yjbK - - S - - - CYTH
NMKGIHNB_01527 3.27e-12 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NMKGIHNB_01528 1.02e-150 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NMKGIHNB_01529 2.52e-89 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NMKGIHNB_01530 2.39e-113 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NMKGIHNB_01531 1.95e-94 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NMKGIHNB_01532 3.41e-78 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
NMKGIHNB_01536 2.77e-104 - - - S - - - Protein conserved in bacteria
NMKGIHNB_01539 1.16e-18 dnaX 2.4.99.16, 2.7.7.7 GH13 D ko:K02343,ko:K02519,ko:K07114,ko:K16147 ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400 cell septum assembly
NMKGIHNB_01540 2.49e-156 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NMKGIHNB_01541 1.31e-41 - - - - - - - -
NMKGIHNB_01543 7.95e-68 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 single-stranded DNA binding
NMKGIHNB_01544 2.48e-13 - - - - - - - -
NMKGIHNB_01545 5.55e-268 - - - M ko:K07114 - ko00000,ko02000 translation initiation factor activity
NMKGIHNB_01546 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMKGIHNB_01547 3.39e-78 - - - - - - - -
NMKGIHNB_01549 1.2e-164 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
NMKGIHNB_01550 3e-116 abiGI - - K - - - Transcriptional regulator, AbiEi antitoxin
NMKGIHNB_01551 2.65e-130 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NMKGIHNB_01554 2.92e-47 - - - - - - - -
NMKGIHNB_01555 9.63e-41 - - - L - - - Helix-turn-helix domain
NMKGIHNB_01556 2.16e-76 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_01558 1.44e-171 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
NMKGIHNB_01559 1.19e-295 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NMKGIHNB_01560 6.14e-60 - - - L - - - COG3547 Transposase and inactivated derivatives
NMKGIHNB_01561 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NMKGIHNB_01562 9.22e-200 - - - L ko:K07497 - ko00000 Integrase core domain protein
NMKGIHNB_01563 1.14e-157 - - - L - - - Helix-turn-helix domain
NMKGIHNB_01564 1.5e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
NMKGIHNB_01566 0.0 - - - NU - - - GBS Bsp-like repeat
NMKGIHNB_01568 3.44e-19 - - - M - - - Psort location Cytoplasmic, score
NMKGIHNB_01570 6.49e-65 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMKGIHNB_01571 1.7e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMKGIHNB_01572 5.59e-272 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
NMKGIHNB_01573 9.29e-157 salX - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_01574 7.29e-248 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMKGIHNB_01575 6.67e-161 - - - J - - - Putative SAM-dependent methyltransferase
NMKGIHNB_01576 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
NMKGIHNB_01577 9.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
NMKGIHNB_01578 5.83e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NMKGIHNB_01579 4.94e-282 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
NMKGIHNB_01580 1.45e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMKGIHNB_01581 2.94e-207 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NMKGIHNB_01582 6.65e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMKGIHNB_01583 9.98e-215 lysR - - K - - - transcriptional regulator (lysR family)
NMKGIHNB_01585 1.06e-128 - - - S - - - Domain of unknown function (DUF1851)
NMKGIHNB_01586 2.99e-74 - - - - - - - -
NMKGIHNB_01589 7.15e-179 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMKGIHNB_01590 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_01592 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
NMKGIHNB_01593 8.23e-52 ynzC - - S - - - UPF0291 protein
NMKGIHNB_01594 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NMKGIHNB_01595 1.23e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NMKGIHNB_01596 1.07e-282 - - - S - - - membrane
NMKGIHNB_01597 4.12e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMKGIHNB_01598 0.0 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NMKGIHNB_01599 8.96e-149 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
NMKGIHNB_01600 2.9e-96 - - - S - - - Bacterial inner membrane protein
NMKGIHNB_01601 2.65e-180 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NMKGIHNB_01602 3.1e-138 mur1 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
NMKGIHNB_01603 5.71e-203 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMKGIHNB_01604 2e-73 yabA - - L - - - Involved in initiation control of chromosome replication
NMKGIHNB_01605 4.74e-176 yaaT - - S - - - stage 0 sporulation protein
NMKGIHNB_01606 1.52e-204 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
NMKGIHNB_01607 9.81e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMKGIHNB_01609 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMKGIHNB_01610 7.68e-174 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMKGIHNB_01611 3.2e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMKGIHNB_01612 5.84e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NMKGIHNB_01613 1.24e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NMKGIHNB_01614 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMKGIHNB_01615 3.7e-201 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMKGIHNB_01616 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMKGIHNB_01617 8.62e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMKGIHNB_01618 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMKGIHNB_01619 4.97e-157 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NMKGIHNB_01620 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMKGIHNB_01621 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMKGIHNB_01622 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
NMKGIHNB_01623 3.65e-128 - - - J - - - Acetyltransferase (GNAT) domain
NMKGIHNB_01624 5.57e-135 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMKGIHNB_01625 1.38e-17 coiA - - S ko:K06198 - ko00000 Competence protein
NMKGIHNB_01627 1.16e-189 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
NMKGIHNB_01628 2.91e-195 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMKGIHNB_01629 8.5e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NMKGIHNB_01630 1.21e-190 icaB - - G - - - deacetylase
NMKGIHNB_01631 1.57e-258 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NMKGIHNB_01632 4.35e-156 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NMKGIHNB_01633 6.13e-278 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMKGIHNB_01634 4.67e-235 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMKGIHNB_01635 4.01e-281 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
NMKGIHNB_01636 4.62e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMKGIHNB_01637 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NMKGIHNB_01639 6.33e-121 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
NMKGIHNB_01640 0.0 - - - M - - - GBS Bsp-like repeat
NMKGIHNB_01641 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMKGIHNB_01642 1.61e-112 XK27_03390 - - S - - - LURP-one-related
NMKGIHNB_01643 1.78e-234 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
NMKGIHNB_01644 5.91e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
NMKGIHNB_01645 8.63e-277 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMKGIHNB_01646 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NMKGIHNB_01647 2.49e-208 coiA - - S ko:K06198 - ko00000 Competence protein
NMKGIHNB_01648 0.0 - - - S - - - Glucan-binding protein C
NMKGIHNB_01649 4.74e-133 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NMKGIHNB_01650 3.03e-215 - - - K - - - transcriptional regulator (lysR family)
NMKGIHNB_01651 1.84e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NMKGIHNB_01652 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMKGIHNB_01656 4e-238 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NMKGIHNB_01657 1.91e-208 sip - - M - - - LysM domain protein
NMKGIHNB_01658 2.72e-46 yozE - - S - - - Belongs to the UPF0346 family
NMKGIHNB_01659 9.52e-205 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
NMKGIHNB_01660 7.89e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMKGIHNB_01661 2.78e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NMKGIHNB_01662 6.48e-269 sptS - - T - - - Histidine kinase
NMKGIHNB_01663 1.18e-150 dltr - - T - - - response regulator
NMKGIHNB_01664 2.51e-143 - 2.7.6.5 - S ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
NMKGIHNB_01665 3.04e-142 - - - K - - - Acetyltransferase (GNAT) family
NMKGIHNB_01666 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01667 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01668 1.59e-94 - - - K - - - DNA-binding transcription factor activity
NMKGIHNB_01669 2.25e-91 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NMKGIHNB_01670 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NMKGIHNB_01671 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NMKGIHNB_01672 2.01e-266 nadR - - H - - - adenylyltransferase
NMKGIHNB_01673 3.47e-166 - - - F - - - AdP-ribose pyrophosphatase
NMKGIHNB_01674 6.23e-30 - - - S - - - Short repeat of unknown function (DUF308)
NMKGIHNB_01675 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01676 5.22e-276 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMKGIHNB_01677 2.58e-178 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMKGIHNB_01678 1.09e-187 - - - S - - - EDD domain protein, DegV family
NMKGIHNB_01679 2.63e-82 WQ51_03320 - - S - - - cog cog4835
NMKGIHNB_01680 2.32e-169 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMKGIHNB_01681 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NMKGIHNB_01682 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NMKGIHNB_01683 3.1e-107 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
NMKGIHNB_01684 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMKGIHNB_01685 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMKGIHNB_01686 1.85e-284 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMKGIHNB_01687 1.93e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NMKGIHNB_01688 1.4e-07 - - - - - - - -
NMKGIHNB_01689 1.37e-286 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NMKGIHNB_01690 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMKGIHNB_01692 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMKGIHNB_01693 6.46e-212 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NMKGIHNB_01694 5.56e-165 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
NMKGIHNB_01695 2.22e-290 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NMKGIHNB_01696 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMKGIHNB_01697 3.8e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMKGIHNB_01698 3.44e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMKGIHNB_01699 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMKGIHNB_01700 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMKGIHNB_01701 1.89e-87 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMKGIHNB_01702 3.69e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMKGIHNB_01703 5.57e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NMKGIHNB_01704 2.73e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NMKGIHNB_01705 1.6e-221 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
NMKGIHNB_01706 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMKGIHNB_01707 2.56e-222 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMKGIHNB_01708 2.67e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
NMKGIHNB_01709 9.63e-181 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
NMKGIHNB_01710 1.25e-150 yhfA - - S - - - HAD hydrolase, family IA, variant 3
NMKGIHNB_01711 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NMKGIHNB_01712 5.34e-245 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NMKGIHNB_01713 3.6e-312 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMKGIHNB_01714 2.16e-167 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NMKGIHNB_01715 1.99e-132 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NMKGIHNB_01716 5.37e-133 - - - S - - - Domain of unknown function (DUF1803)
NMKGIHNB_01717 7.18e-208 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NMKGIHNB_01725 4.11e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMKGIHNB_01726 8.3e-128 comFC - - K ko:K02242 - ko00000,ko00002,ko02044 competence protein
NMKGIHNB_01727 8.17e-302 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMKGIHNB_01728 6.4e-142 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NMKGIHNB_01729 2.34e-212 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NMKGIHNB_01730 4.25e-141 XK27_04065 - - S ko:K04767 - ko00000 CBS domain
NMKGIHNB_01731 4.6e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NMKGIHNB_01732 8.95e-174 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NMKGIHNB_01733 1.64e-184 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMKGIHNB_01734 6.72e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMKGIHNB_01735 1.62e-266 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NMKGIHNB_01736 1.51e-62 ylbG - - S - - - UPF0298 protein
NMKGIHNB_01737 1.3e-94 ylbF - - S - - - Belongs to the UPF0342 family
NMKGIHNB_01738 3.75e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMKGIHNB_01739 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMKGIHNB_01740 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
NMKGIHNB_01741 0.0 - 3.2.1.26, 3.2.1.65 GH32 G ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NMKGIHNB_01742 3.19e-284 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMKGIHNB_01743 3.41e-256 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NMKGIHNB_01744 0.0 pacL - - P - - - cation transport ATPase
NMKGIHNB_01745 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NMKGIHNB_01746 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMKGIHNB_01747 1.48e-238 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
NMKGIHNB_01748 5.37e-126 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NMKGIHNB_01749 5.68e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMKGIHNB_01750 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMKGIHNB_01751 1.66e-56 ylxQ - - J - - - ribosomal protein
NMKGIHNB_01752 1.31e-63 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
NMKGIHNB_01753 8.46e-253 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NMKGIHNB_01754 1.75e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NMKGIHNB_01755 1.75e-264 brpA - - K - - - Transcriptional
NMKGIHNB_01756 1.69e-113 XK27_05885 2.3.1.82 - M ko:K18816 - br01600,ko00000,ko01000,ko01504 phosphinothricin N-acetyltransferase activity
NMKGIHNB_01757 1.79e-100 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
NMKGIHNB_01758 7.03e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
NMKGIHNB_01759 6.93e-195 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NMKGIHNB_01760 9.8e-177 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
NMKGIHNB_01761 1.65e-221 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_01762 2.07e-169 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
NMKGIHNB_01763 3.97e-202 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NMKGIHNB_01764 9.41e-87 manO - - S - - - Protein conserved in bacteria
NMKGIHNB_01765 2.3e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_01766 6.23e-162 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
NMKGIHNB_01767 1.59e-212 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NMKGIHNB_01768 2.53e-80 manO - - S - - - protein conserved in bacteria
NMKGIHNB_01769 4.62e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMKGIHNB_01770 2.04e-134 - - - - - - - -
NMKGIHNB_01771 4.15e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NMKGIHNB_01772 2.54e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NMKGIHNB_01773 2.18e-268 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
NMKGIHNB_01774 8.3e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMKGIHNB_01775 0.0 covS - - T - - - Histidine kinase
NMKGIHNB_01776 1.62e-159 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMKGIHNB_01777 3.66e-115 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NMKGIHNB_01778 1.38e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
NMKGIHNB_01779 1.59e-297 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
NMKGIHNB_01780 6.09e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NMKGIHNB_01781 3.96e-188 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NMKGIHNB_01782 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01783 8.98e-122 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NMKGIHNB_01784 1.2e-201 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
NMKGIHNB_01785 3.3e-264 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NMKGIHNB_01786 1.27e-152 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_01787 1.1e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMKGIHNB_01788 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NMKGIHNB_01789 2e-209 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NMKGIHNB_01790 9.97e-185 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NMKGIHNB_01791 1.82e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMKGIHNB_01792 5.36e-173 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
NMKGIHNB_01793 4.11e-226 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NMKGIHNB_01794 4.04e-203 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NMKGIHNB_01795 2.72e-141 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NMKGIHNB_01796 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NMKGIHNB_01797 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
NMKGIHNB_01798 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMKGIHNB_01799 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NMKGIHNB_01800 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NMKGIHNB_01801 2.16e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
NMKGIHNB_01802 0.0 - - - S - - - Domain of unknown function (DUF4173)
NMKGIHNB_01803 2.12e-70 yhaI - - L - - - Membrane
NMKGIHNB_01804 0.0 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMKGIHNB_01805 7.41e-200 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NMKGIHNB_01806 3.71e-129 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
NMKGIHNB_01807 2.85e-110 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMKGIHNB_01808 6.48e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMKGIHNB_01809 5.21e-310 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
NMKGIHNB_01810 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
NMKGIHNB_01811 4.11e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NMKGIHNB_01812 1.23e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NMKGIHNB_01813 1.99e-124 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMKGIHNB_01814 1.31e-153 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMKGIHNB_01815 4.75e-165 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NMKGIHNB_01816 3.01e-112 ykuL - - S - - - CBS domain
NMKGIHNB_01817 1.2e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NMKGIHNB_01818 7.16e-231 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMKGIHNB_01819 2.4e-191 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NMKGIHNB_01820 2.31e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
NMKGIHNB_01821 2.11e-115 - - - K - - - transcriptional regulator
NMKGIHNB_01822 7.87e-308 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMKGIHNB_01824 2e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NMKGIHNB_01825 2.55e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
NMKGIHNB_01826 3.63e-164 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMKGIHNB_01827 7.55e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NMKGIHNB_01828 3.44e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMKGIHNB_01829 4.77e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMKGIHNB_01830 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMKGIHNB_01831 5.79e-112 - - - K - - - histone acetyltransferase HPA2 and related acetyltransferases
NMKGIHNB_01832 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NMKGIHNB_01833 3.69e-27 XK27_11680 - - - - - - -
NMKGIHNB_01834 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
NMKGIHNB_01835 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NMKGIHNB_01836 4.34e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NMKGIHNB_01837 8.01e-66 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMKGIHNB_01838 6.97e-121 ypsA - - S - - - Belongs to the UPF0398 family
NMKGIHNB_01839 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMKGIHNB_01840 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMKGIHNB_01841 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NMKGIHNB_01842 1.86e-93 yhaH - - S - - - Protein of unknown function (DUF805)
NMKGIHNB_01843 4.85e-192 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMKGIHNB_01844 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMKGIHNB_01845 4.33e-259 - - - V - - - FtsX-like permease family
NMKGIHNB_01846 1.82e-155 - - - V - - - abc transporter atp-binding protein
NMKGIHNB_01847 3.94e-159 mta - - K ko:K21743 - ko00000,ko03000 Transcriptional
NMKGIHNB_01848 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NMKGIHNB_01849 6.26e-170 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
NMKGIHNB_01850 1.43e-182 cof - - S - - - Sucrose-6F-phosphate phosphohydrolase
NMKGIHNB_01851 1.07e-92 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
NMKGIHNB_01852 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NMKGIHNB_01853 1.05e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
NMKGIHNB_01854 2.73e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NMKGIHNB_01855 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMKGIHNB_01856 2.25e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NMKGIHNB_01857 5.41e-73 WQ51_06355 - - S - - - TM2 domain
NMKGIHNB_01858 4.19e-60 - - - - - - - -
NMKGIHNB_01860 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMKGIHNB_01861 1.28e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMKGIHNB_01862 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NMKGIHNB_01863 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
NMKGIHNB_01864 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMKGIHNB_01865 1.05e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NMKGIHNB_01866 7.14e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NMKGIHNB_01867 3.56e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMKGIHNB_01868 1.73e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
NMKGIHNB_01869 3.37e-161 yeeN - - K - - - transcriptional regulatory protein
NMKGIHNB_01870 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
NMKGIHNB_01871 4.43e-192 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NMKGIHNB_01872 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NMKGIHNB_01873 1.67e-201 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
NMKGIHNB_01874 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_01875 4.3e-202 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NMKGIHNB_01876 8.57e-164 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NMKGIHNB_01877 1.19e-173 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMKGIHNB_01878 7.14e-92 adcR - - K - - - transcriptional
NMKGIHNB_01879 1.98e-232 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMKGIHNB_01880 1.34e-201 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMKGIHNB_01881 2.48e-34 - - - - - - - -
NMKGIHNB_01882 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NMKGIHNB_01883 4.28e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NMKGIHNB_01884 5.02e-295 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMKGIHNB_01885 1.98e-297 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NMKGIHNB_01886 1.65e-176 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMKGIHNB_01887 3.65e-241 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NMKGIHNB_01888 4.23e-165 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NMKGIHNB_01890 1.75e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMKGIHNB_01891 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMKGIHNB_01892 4.26e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NMKGIHNB_01893 9.08e-310 - - - D - - - nuclear chromosome segregation
NMKGIHNB_01894 4.84e-122 - - - V - - - VanZ like family
NMKGIHNB_01895 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMKGIHNB_01896 5.34e-227 XK27_00055 - - P - - - Major Facilitator
NMKGIHNB_01897 3.25e-137 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NMKGIHNB_01898 5.97e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMKGIHNB_01899 1.84e-300 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMKGIHNB_01900 0.0 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NMKGIHNB_01901 3.91e-95 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMKGIHNB_01902 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMKGIHNB_01903 6.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NMKGIHNB_01904 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMKGIHNB_01905 3.78e-167 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMKGIHNB_01906 1.67e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NMKGIHNB_01907 9.21e-99 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NMKGIHNB_01908 2.5e-109 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NMKGIHNB_01909 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMKGIHNB_01910 1.24e-101 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMKGIHNB_01911 1.28e-292 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMKGIHNB_01912 2.18e-174 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NMKGIHNB_01913 2.18e-112 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
NMKGIHNB_01916 9.74e-103 hmpT - - S - - - cog cog4720
NMKGIHNB_01917 2.04e-174 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
NMKGIHNB_01918 1.06e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMKGIHNB_01919 6.04e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMKGIHNB_01920 7.63e-138 thiJ-2 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NMKGIHNB_01922 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NMKGIHNB_01923 2.34e-103 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMKGIHNB_01924 5.71e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMKGIHNB_01925 9.58e-130 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Muramidase (Flagellum-specific)
NMKGIHNB_01926 1.6e-177 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NMKGIHNB_01927 3.99e-167 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
NMKGIHNB_01928 1.73e-306 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NMKGIHNB_01929 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
NMKGIHNB_01930 2.57e-296 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
NMKGIHNB_01931 2.05e-191 srtB - - S - - - Sortase family
NMKGIHNB_01933 3.02e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
NMKGIHNB_01935 1.73e-19 - - - S - - - Protein of unknown function (DUF1211)
NMKGIHNB_01936 6.88e-66 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NMKGIHNB_01938 9.76e-204 trxB1 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMKGIHNB_01939 2.29e-62 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NMKGIHNB_01940 1.37e-127 - - - K - - - Rhodanese Homology Domain
NMKGIHNB_01941 2.55e-216 lacX - - G - - - Aldose 1-epimerase
NMKGIHNB_01942 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMKGIHNB_01943 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NMKGIHNB_01944 1.12e-65 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NMKGIHNB_01945 1.69e-230 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NMKGIHNB_01946 4.91e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NMKGIHNB_01947 8.35e-94 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NMKGIHNB_01948 3.87e-164 lacR - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
NMKGIHNB_01949 3.25e-102 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NMKGIHNB_01950 3.9e-119 - - - K - - - Replication initiation factor
NMKGIHNB_01951 4.52e-37 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
NMKGIHNB_01952 7.13e-141 - - - S - - - Septin
NMKGIHNB_01953 2.24e-46 - - - S - - - Septin
NMKGIHNB_01954 7.93e-59 - - - S - - - Helix-turn-helix domain
NMKGIHNB_01955 3.61e-244 int - - L - - - Belongs to the 'phage' integrase family
NMKGIHNB_01956 2.97e-56 - - - S - - - Protein of unknown function (DUF1211)
NMKGIHNB_01957 1.17e-23 - - - - - - - -
NMKGIHNB_01958 4.31e-73 cadX - - K ko:K21903 - ko00000,ko03000 transcriptional regulator, ArsR family
NMKGIHNB_01959 1.05e-129 cadD - - P - - - Cadmium resistance transporter
NMKGIHNB_01961 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
NMKGIHNB_01962 6.48e-104 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
NMKGIHNB_01963 2.12e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NMKGIHNB_01964 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMKGIHNB_01965 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
NMKGIHNB_01967 1.18e-194 yitS - - S - - - DegV family
NMKGIHNB_01968 5.73e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NMKGIHNB_01969 1.01e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMKGIHNB_01971 1.22e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMKGIHNB_01972 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NMKGIHNB_01973 6.37e-144 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
NMKGIHNB_01974 1.18e-179 - - - S - - - SseB protein N-terminal domain
NMKGIHNB_01975 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMKGIHNB_01976 4.21e-289 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NMKGIHNB_01977 7.56e-293 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NMKGIHNB_01978 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NMKGIHNB_01979 1.92e-97 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NMKGIHNB_01980 3.41e-107 - - - S - - - Putative small multi-drug export protein
NMKGIHNB_01981 1.23e-233 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMKGIHNB_01982 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NMKGIHNB_01983 1.73e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 alkyl hydroperoxide reductase
NMKGIHNB_01984 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase
NMKGIHNB_01986 6.07e-120 XK27_03570 - - S ko:K19784 - ko00000 reductase
NMKGIHNB_01987 4.46e-94 - - - K - - - Transcriptional regulator, marr family
NMKGIHNB_01988 1.4e-48 XK27_02060 - - S - - - Transglycosylase associated protein
NMKGIHNB_01989 2.07e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMKGIHNB_01990 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMKGIHNB_02004 8.92e-87 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NMKGIHNB_02005 4.16e-260 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMKGIHNB_02006 7.57e-287 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NMKGIHNB_02007 4.37e-134 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
NMKGIHNB_02008 1.47e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMKGIHNB_02010 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMKGIHNB_02012 8.9e-91 - - - K - - - LytTr DNA-binding domain
NMKGIHNB_02013 3.59e-102 - - - S - - - Protein of unknown function (DUF3021)
NMKGIHNB_02014 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMKGIHNB_02015 1.01e-70 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NMKGIHNB_02016 4.46e-89 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NMKGIHNB_02017 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NMKGIHNB_02018 2.14e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMKGIHNB_02020 5.3e-184 - - - J - - - Domain of unknown function (DUF4041)
NMKGIHNB_02021 3.12e-46 - - - - - - - -
NMKGIHNB_02022 8.67e-228 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
NMKGIHNB_02023 1.28e-255 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMKGIHNB_02024 6.76e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMKGIHNB_02025 4.35e-301 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NMKGIHNB_02026 4.31e-199 - - - S - - - CHAP domain
NMKGIHNB_02027 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NMKGIHNB_02028 1.05e-63 - - - - - - - -
NMKGIHNB_02029 1.41e-126 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMKGIHNB_02030 4.55e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NMKGIHNB_02031 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMKGIHNB_02032 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMKGIHNB_02033 8.69e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NMKGIHNB_02034 1.47e-41 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMKGIHNB_02035 1.19e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMKGIHNB_02036 1.74e-177 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NMKGIHNB_02037 7.11e-274 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NMKGIHNB_02038 1.36e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMKGIHNB_02039 5.56e-287 - - - L - - - Transposase
NMKGIHNB_02040 1.75e-145 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
NMKGIHNB_02041 9.73e-109 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NMKGIHNB_02042 2.38e-157 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NMKGIHNB_02061 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMKGIHNB_02062 3.15e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NMKGIHNB_02063 5.63e-293 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMKGIHNB_02064 6.42e-299 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
NMKGIHNB_02066 3.9e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NMKGIHNB_02067 1.87e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMKGIHNB_02068 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMKGIHNB_02069 3.5e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMKGIHNB_02070 3.04e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMKGIHNB_02071 8.11e-40 yyzM - - S - - - Protein conserved in bacteria
NMKGIHNB_02072 1.95e-253 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMKGIHNB_02073 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMKGIHNB_02074 6.53e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NMKGIHNB_02075 5.83e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NMKGIHNB_02076 4.8e-104 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMKGIHNB_02077 1.5e-151 yoaK - - S - - - Protein of unknown function (DUF1275)
NMKGIHNB_02081 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
NMKGIHNB_02082 0.0 ykpA - - S - - - abc transporter atp-binding protein
NMKGIHNB_02083 1.09e-192 XK27_10395 - - S - - - membrane
NMKGIHNB_02084 1.07e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NMKGIHNB_02085 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMKGIHNB_02086 7.69e-254 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMKGIHNB_02087 4.18e-75 yaaA - - S - - - S4 domain protein YaaA
NMKGIHNB_02088 4.45e-292 albE - - S - - - Peptidase M16
NMKGIHNB_02089 2.4e-296 ymfH - - S - - - Peptidase M16
NMKGIHNB_02090 1.93e-165 - - - S ko:K15539 - ko00000 sequence-specific DNA binding
NMKGIHNB_02091 3.12e-117 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMKGIHNB_02092 1.23e-191 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMKGIHNB_02093 2.05e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMKGIHNB_02094 2.63e-171 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMKGIHNB_02095 6.93e-106 lytE - - M - - - LysM domain protein
NMKGIHNB_02096 2.05e-127 isaA - - M - - - Immunodominant staphylococcal antigen A
NMKGIHNB_02097 0.0 - - - S - - - Bacterial membrane protein, YfhO
NMKGIHNB_02098 1.09e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMKGIHNB_02099 2.48e-128 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NMKGIHNB_02100 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMKGIHNB_02101 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NMKGIHNB_02102 1.77e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NMKGIHNB_02103 1.1e-313 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NMKGIHNB_02104 6.16e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
NMKGIHNB_02105 1.25e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMKGIHNB_02106 5.32e-13 - - - - - - - -
NMKGIHNB_02107 4.43e-70 XK27_04840 - - M ko:K08987 - ko00000 Membrane
NMKGIHNB_02108 9.01e-121 XK27_06935 - - K - - - transcriptional regulator
NMKGIHNB_02109 9.88e-260 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NMKGIHNB_02110 1.53e-146 - - - S - - - Putative adhesin
NMKGIHNB_02111 1.21e-98 - - - S - - - Protein of unknown function (DUF1700)
NMKGIHNB_02112 1.24e-68 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
NMKGIHNB_02113 1.59e-148 XK27_06885 - - L - - - hydrolase
NMKGIHNB_02117 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NMKGIHNB_02118 3.57e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NMKGIHNB_02119 5.84e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NMKGIHNB_02120 0.000652 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system
NMKGIHNB_02121 1.19e-16 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_02122 3.09e-138 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NMKGIHNB_02123 4.03e-300 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NMKGIHNB_02125 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NMKGIHNB_02126 1.03e-213 XK27_01785 - - S - - - cog cog1284
NMKGIHNB_02127 1.19e-154 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NMKGIHNB_02128 7.01e-147 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMKGIHNB_02129 1.93e-111 - - - K - - - acetyltransferase
NMKGIHNB_02130 7.68e-20 - - - - - - - -
NMKGIHNB_02131 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NMKGIHNB_02132 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_02133 5.46e-62 yrzB - - S - - - Belongs to the UPF0473 family
NMKGIHNB_02134 9.82e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMKGIHNB_02135 9.75e-59 yrzL - - S - - - Belongs to the UPF0297 family
NMKGIHNB_02136 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NMKGIHNB_02137 2.58e-298 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
NMKGIHNB_02139 1.75e-277 - - - L - - - Belongs to the 'phage' integrase family
NMKGIHNB_02140 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
NMKGIHNB_02141 3.95e-208 - - - L - - - Replication initiation factor
NMKGIHNB_02142 1.85e-115 - - - K - - - sequence-specific DNA binding
NMKGIHNB_02143 3.44e-219 - - - S - - - membrane
NMKGIHNB_02145 5.95e-114 flaR - - F - - - topology modulation protein
NMKGIHNB_02146 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMKGIHNB_02147 1.55e-104 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMKGIHNB_02148 1.21e-47 - - - S - - - MORN repeat protein
NMKGIHNB_02149 0.0 XK27_09800 - - I - - - Acyltransferase
NMKGIHNB_02150 7.25e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMKGIHNB_02151 4.29e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NMKGIHNB_02152 3.17e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMKGIHNB_02153 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NMKGIHNB_02154 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMKGIHNB_02155 5.06e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMKGIHNB_02156 8.13e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMKGIHNB_02157 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMKGIHNB_02158 9.44e-153 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMKGIHNB_02159 4.35e-94 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMKGIHNB_02160 6.2e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NMKGIHNB_02161 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMKGIHNB_02162 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMKGIHNB_02163 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMKGIHNB_02164 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMKGIHNB_02165 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMKGIHNB_02166 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMKGIHNB_02167 2.4e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMKGIHNB_02168 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMKGIHNB_02169 7e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMKGIHNB_02170 9.89e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
NMKGIHNB_02171 8.47e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NMKGIHNB_02172 8.65e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMKGIHNB_02173 1.7e-148 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMKGIHNB_02174 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMKGIHNB_02175 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NMKGIHNB_02176 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMKGIHNB_02177 1.63e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMKGIHNB_02178 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMKGIHNB_02179 3.03e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
NMKGIHNB_02180 9.41e-279 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
NMKGIHNB_02181 8.03e-314 - - - H - - - gamma-glutamylcysteine synthetase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)