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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MFCOLMCK_00001	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFCOLMCK_00002	5.38e-39	-	-	-	-	-	-	-	-
MFCOLMCK_00003	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MFCOLMCK_00004	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFCOLMCK_00005	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFCOLMCK_00006	2.27e-190	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFCOLMCK_00007	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFCOLMCK_00008	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MFCOLMCK_00009	1.92e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFCOLMCK_00010	1.23e-239	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFCOLMCK_00011	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MFCOLMCK_00012	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFCOLMCK_00013	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFCOLMCK_00014	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFCOLMCK_00015	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MFCOLMCK_00016	7.46e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFCOLMCK_00017	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFCOLMCK_00019	3.11e-13	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFCOLMCK_00020	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
MFCOLMCK_00021	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
MFCOLMCK_00022	3.92e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MFCOLMCK_00023	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
MFCOLMCK_00024	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
MFCOLMCK_00025	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MFCOLMCK_00026	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
MFCOLMCK_00028	1.09e-46	-	-	-	-	-	-	-	-
MFCOLMCK_00030	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MFCOLMCK_00031	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MFCOLMCK_00032	0.0	yycH	-	-	S	-	-	-	YycH protein
MFCOLMCK_00033	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
MFCOLMCK_00034	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MFCOLMCK_00035	7.81e-225	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MFCOLMCK_00036	2.99e-07	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MFCOLMCK_00037	2.28e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MFCOLMCK_00038	1.48e-136	-	-	-	L	-	-	-	PFAM Integrase catalytic
MFCOLMCK_00039	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MFCOLMCK_00040	3.23e-59	-	-	-	-	-	-	-	-
MFCOLMCK_00041	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MFCOLMCK_00042	7.73e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MFCOLMCK_00043	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MFCOLMCK_00044	5.01e-150	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MFCOLMCK_00045	7.68e-63	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MFCOLMCK_00046	1.43e-309	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MFCOLMCK_00047	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFCOLMCK_00048	0.0	potE	-	-	E	-	-	-	Amino Acid
MFCOLMCK_00049	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
MFCOLMCK_00050	0.0	-	-	-	-	-	-	-	-
MFCOLMCK_00051	5.87e-110	-	-	-	-	-	-	-	-
MFCOLMCK_00052	1.92e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MFCOLMCK_00053	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
MFCOLMCK_00054	1.36e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MFCOLMCK_00055	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
MFCOLMCK_00056	4e-31	dltr	-	-	K	-	-	-	response regulator
MFCOLMCK_00057	6.89e-93	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MFCOLMCK_00058	2.14e-48	-	-	-	-	-	-	-	-
MFCOLMCK_00059	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MFCOLMCK_00060	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MFCOLMCK_00061	4.16e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFCOLMCK_00062	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MFCOLMCK_00063	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MFCOLMCK_00064	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MFCOLMCK_00065	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MFCOLMCK_00066	5.9e-183	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MFCOLMCK_00067	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MFCOLMCK_00068	2.44e-210	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MFCOLMCK_00069	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
MFCOLMCK_00070	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MFCOLMCK_00071	1.21e-289	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MFCOLMCK_00073	2.09e-205	-	-	-	-	-	-	-	-
MFCOLMCK_00074	2.37e-219	-	-	-	-	-	-	-	-
MFCOLMCK_00075	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MFCOLMCK_00076	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
MFCOLMCK_00077	9.03e-215	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFCOLMCK_00078	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MFCOLMCK_00079	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MFCOLMCK_00080	3.25e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MFCOLMCK_00081	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFCOLMCK_00082	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MFCOLMCK_00083	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MFCOLMCK_00084	0.0	-	-	-	S	-	-	-	membrane
MFCOLMCK_00085	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MFCOLMCK_00086	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MFCOLMCK_00087	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MFCOLMCK_00088	5.25e-59	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFCOLMCK_00089	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
MFCOLMCK_00090	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFCOLMCK_00091	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MFCOLMCK_00092	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MFCOLMCK_00094	6.09e-121	-	-	-	-	-	-	-	-
MFCOLMCK_00095	1.29e-164	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00096	4.34e-64	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFCOLMCK_00097	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_00098	1.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MFCOLMCK_00099	5.84e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
MFCOLMCK_00100	2.77e-292	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MFCOLMCK_00101	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MFCOLMCK_00102	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MFCOLMCK_00103	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MFCOLMCK_00104	1.8e-34	-	-	-	-	-	-	-	-
MFCOLMCK_00105	5.5e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MFCOLMCK_00106	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MFCOLMCK_00107	1.72e-92	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFCOLMCK_00108	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFCOLMCK_00109	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFCOLMCK_00110	8.08e-117	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00111	1.02e-67	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00112	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00113	4.11e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00114	1.8e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MFCOLMCK_00116	4.87e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MFCOLMCK_00117	3.23e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFCOLMCK_00118	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MFCOLMCK_00119	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFCOLMCK_00120	2.08e-95	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MFCOLMCK_00121	2.42e-69	-	-	-	S	-	-	-	Abi-like protein
MFCOLMCK_00122	7.24e-284	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00123	9.04e-162	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MFCOLMCK_00124	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
MFCOLMCK_00125	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
MFCOLMCK_00126	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
MFCOLMCK_00127	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MFCOLMCK_00128	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MFCOLMCK_00129	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00130	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MFCOLMCK_00131	1.16e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MFCOLMCK_00132	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MFCOLMCK_00133	2.12e-213	ysdE	-	-	P	-	-	-	Citrate transporter
MFCOLMCK_00134	2.24e-05	ysdE	-	-	P	-	-	-	Citrate transporter
MFCOLMCK_00135	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MFCOLMCK_00136	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MFCOLMCK_00137	9.69e-25	-	-	-	-	-	-	-	-
MFCOLMCK_00138	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MFCOLMCK_00139	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
MFCOLMCK_00140	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MFCOLMCK_00141	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MFCOLMCK_00142	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
MFCOLMCK_00143	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MFCOLMCK_00144	3.52e-163	csrR	-	-	K	-	-	-	response regulator
MFCOLMCK_00145	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MFCOLMCK_00146	4.63e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MFCOLMCK_00147	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFCOLMCK_00148	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MFCOLMCK_00149	1.77e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFCOLMCK_00150	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MFCOLMCK_00151	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MFCOLMCK_00152	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MFCOLMCK_00153	1.25e-192	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MFCOLMCK_00154	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFCOLMCK_00155	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MFCOLMCK_00156	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFCOLMCK_00157	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MFCOLMCK_00158	8.96e-49	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_00159	6.49e-137	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_00160	1.53e-122	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_00161	4.78e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MFCOLMCK_00162	6.7e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MFCOLMCK_00163	5.59e-98	-	-	-	-	-	-	-	-
MFCOLMCK_00164	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFCOLMCK_00165	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MFCOLMCK_00166	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MFCOLMCK_00167	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFCOLMCK_00168	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFCOLMCK_00169	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFCOLMCK_00170	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFCOLMCK_00171	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MFCOLMCK_00172	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MFCOLMCK_00173	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MFCOLMCK_00174	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MFCOLMCK_00175	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
MFCOLMCK_00176	2.04e-226	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00177	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MFCOLMCK_00178	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MFCOLMCK_00179	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFCOLMCK_00180	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
MFCOLMCK_00182	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFCOLMCK_00183	1.1e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MFCOLMCK_00184	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00185	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MFCOLMCK_00186	1.2e-41	-	-	-	-	-	-	-	-
MFCOLMCK_00187	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFCOLMCK_00188	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
MFCOLMCK_00189	0.0	-	-	-	-	-	-	-	-
MFCOLMCK_00192	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MFCOLMCK_00193	0.0	yhaN	-	-	L	-	-	-	AAA domain
MFCOLMCK_00194	4.24e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MFCOLMCK_00195	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MFCOLMCK_00196	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MFCOLMCK_00197	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MFCOLMCK_00198	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFCOLMCK_00199	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MFCOLMCK_00200	5.46e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MFCOLMCK_00201	2.74e-06	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00202	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MFCOLMCK_00203	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MFCOLMCK_00204	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00205	1.86e-91	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_00206	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_00207	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_00208	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MFCOLMCK_00209	7.84e-95	-	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_00210	2.58e-45	-	-	-	-	-	-	-	-
MFCOLMCK_00212	3.3e-42	-	-	-	-	-	-	-	-
MFCOLMCK_00213	3.98e-97	-	-	-	M	-	-	-	LysM domain
MFCOLMCK_00214	1.5e-27	-	-	-	S	-	-	-	Enterocin A Immunity
MFCOLMCK_00216	1.23e-54	-	-	-	V	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
MFCOLMCK_00217	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MFCOLMCK_00218	1.64e-101	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MFCOLMCK_00219	1.79e-99	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MFCOLMCK_00220	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MFCOLMCK_00221	7.02e-36	-	-	-	-	-	-	-	-
MFCOLMCK_00222	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00223	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00224	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MFCOLMCK_00225	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MFCOLMCK_00226	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MFCOLMCK_00227	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFCOLMCK_00228	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MFCOLMCK_00230	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MFCOLMCK_00231	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MFCOLMCK_00232	1.4e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MFCOLMCK_00233	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00234	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00235	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MFCOLMCK_00236	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MFCOLMCK_00237	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MFCOLMCK_00238	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MFCOLMCK_00239	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MFCOLMCK_00240	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MFCOLMCK_00241	2.21e-155	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MFCOLMCK_00242	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MFCOLMCK_00243	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFCOLMCK_00244	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MFCOLMCK_00245	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MFCOLMCK_00246	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MFCOLMCK_00247	4.84e-42	-	-	-	-	-	-	-	-
MFCOLMCK_00248	3.11e-256	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_00249	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MFCOLMCK_00250	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MFCOLMCK_00251	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MFCOLMCK_00252	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MFCOLMCK_00253	9.32e-109	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MFCOLMCK_00254	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MFCOLMCK_00255	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MFCOLMCK_00256	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MFCOLMCK_00257	8.31e-228	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MFCOLMCK_00258	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFCOLMCK_00259	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MFCOLMCK_00260	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MFCOLMCK_00261	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MFCOLMCK_00262	7.25e-309	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MFCOLMCK_00263	8.22e-63	-	-	-	K	-	-	-	rpiR family
MFCOLMCK_00264	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MFCOLMCK_00265	1.81e-270	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_00266	1.32e-151	-	-	-	S	-	-	-	Putative esterase
MFCOLMCK_00267	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFCOLMCK_00268	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MFCOLMCK_00270	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_00271	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFCOLMCK_00274	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MFCOLMCK_00276	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MFCOLMCK_00277	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MFCOLMCK_00278	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MFCOLMCK_00279	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MFCOLMCK_00280	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFCOLMCK_00281	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MFCOLMCK_00282	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MFCOLMCK_00283	4.17e-193	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MFCOLMCK_00284	1.67e-80	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MFCOLMCK_00285	4.06e-109	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MFCOLMCK_00286	9.75e-20	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_00287	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_00288	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MFCOLMCK_00289	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MFCOLMCK_00290	3.24e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MFCOLMCK_00291	1.2e-220	-	-	-	-	-	-	-	-
MFCOLMCK_00292	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_00294	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MFCOLMCK_00295	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MFCOLMCK_00296	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MFCOLMCK_00297	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MFCOLMCK_00298	1.23e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MFCOLMCK_00299	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MFCOLMCK_00300	3.25e-186	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_00301	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MFCOLMCK_00302	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MFCOLMCK_00303	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MFCOLMCK_00304	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MFCOLMCK_00305	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MFCOLMCK_00306	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MFCOLMCK_00307	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MFCOLMCK_00308	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MFCOLMCK_00309	5.42e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MFCOLMCK_00310	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MFCOLMCK_00311	6.31e-84	-	-	-	-	-	-	-	-
MFCOLMCK_00312	2.62e-69	-	-	-	-	-	-	-	-
MFCOLMCK_00314	4.4e-165	-	-	-	S	-	-	-	PAS domain
MFCOLMCK_00316	2.29e-112	-	-	-	-	-	-	-	-
MFCOLMCK_00317	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFCOLMCK_00318	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MFCOLMCK_00319	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFCOLMCK_00320	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MFCOLMCK_00321	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MFCOLMCK_00322	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MFCOLMCK_00323	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MFCOLMCK_00324	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MFCOLMCK_00325	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MFCOLMCK_00326	2.37e-242	-	-	-	T	-	-	-	GHKL domain
MFCOLMCK_00327	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MFCOLMCK_00328	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MFCOLMCK_00329	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MFCOLMCK_00330	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_00331	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MFCOLMCK_00332	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MFCOLMCK_00333	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_00334	1.73e-79	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MFCOLMCK_00335	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MFCOLMCK_00336	2.15e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MFCOLMCK_00337	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MFCOLMCK_00338	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFCOLMCK_00339	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MFCOLMCK_00340	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MFCOLMCK_00341	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_00342	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00343	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MFCOLMCK_00344	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00345	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MFCOLMCK_00346	1.51e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MFCOLMCK_00347	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MFCOLMCK_00348	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
MFCOLMCK_00349	1.34e-162	-	-	-	-	-	-	-	-
MFCOLMCK_00350	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MFCOLMCK_00351	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MFCOLMCK_00352	1.42e-57	-	-	-	-	-	-	-	-
MFCOLMCK_00353	4.65e-14	-	-	-	-	-	-	-	-
MFCOLMCK_00354	7.81e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MFCOLMCK_00355	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MFCOLMCK_00356	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
MFCOLMCK_00357	1.45e-133	-	-	-	-	-	-	-	-
MFCOLMCK_00360	9.92e-152	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MFCOLMCK_00361	2.91e-140	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MFCOLMCK_00362	2.22e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MFCOLMCK_00363	5.61e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MFCOLMCK_00364	5.52e-187	epsB	-	-	M	-	-	-	biosynthesis protein
MFCOLMCK_00365	8.14e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MFCOLMCK_00367	6.72e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFCOLMCK_00368	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MFCOLMCK_00369	3.01e-54	-	-	-	-	-	-	-	-
MFCOLMCK_00370	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MFCOLMCK_00371	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MFCOLMCK_00372	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MFCOLMCK_00373	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MFCOLMCK_00374	4.52e-56	-	-	-	-	-	-	-	-
MFCOLMCK_00375	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MFCOLMCK_00376	8.77e-144	-	-	-	-	-	-	-	-
MFCOLMCK_00377	5.48e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MFCOLMCK_00378	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MFCOLMCK_00379	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFCOLMCK_00380	1.16e-101	-	-	-	-	-	-	-	-
MFCOLMCK_00381	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
MFCOLMCK_00382	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MFCOLMCK_00383	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
MFCOLMCK_00384	0.0	-	-	-	S	-	-	-	ABC transporter
MFCOLMCK_00385	2.52e-76	-	-	-	-	-	-	-	-
MFCOLMCK_00386	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MFCOLMCK_00387	5.49e-46	-	-	-	-	-	-	-	-
MFCOLMCK_00388	7.2e-40	-	-	-	-	-	-	-	-
MFCOLMCK_00389	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MFCOLMCK_00390	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MFCOLMCK_00391	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MFCOLMCK_00392	7.27e-42	-	-	-	-	-	-	-	-
MFCOLMCK_00393	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
MFCOLMCK_00396	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
MFCOLMCK_00399	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00400	0.000868	-	-	-	-	-	-	-	-
MFCOLMCK_00401	2.04e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MFCOLMCK_00402	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFCOLMCK_00403	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MFCOLMCK_00404	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MFCOLMCK_00405	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MFCOLMCK_00406	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MFCOLMCK_00407	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MFCOLMCK_00408	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MFCOLMCK_00409	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MFCOLMCK_00410	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MFCOLMCK_00411	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MFCOLMCK_00412	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00413	3.41e-88	-	-	-	-	-	-	-	-
MFCOLMCK_00414	2.52e-32	-	-	-	-	-	-	-	-
MFCOLMCK_00415	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MFCOLMCK_00416	3e-92	-	-	-	-	-	-	-	-
MFCOLMCK_00417	7.87e-30	-	-	-	-	-	-	-	-
MFCOLMCK_00421	5.02e-180	blpT	-	-	-	-	-	-	-
MFCOLMCK_00422	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MFCOLMCK_00423	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MFCOLMCK_00424	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MFCOLMCK_00425	8.83e-170	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MFCOLMCK_00426	1.89e-23	-	-	-	-	-	-	-	-
MFCOLMCK_00427	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MFCOLMCK_00428	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MFCOLMCK_00429	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MFCOLMCK_00430	4.48e-34	-	-	-	-	-	-	-	-
MFCOLMCK_00431	1.07e-35	-	-	-	-	-	-	-	-
MFCOLMCK_00432	1.95e-45	-	-	-	-	-	-	-	-
MFCOLMCK_00433	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MFCOLMCK_00434	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MFCOLMCK_00435	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFCOLMCK_00436	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MFCOLMCK_00437	8.32e-157	vanR	-	-	K	-	-	-	response regulator
MFCOLMCK_00439	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MFCOLMCK_00440	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00441	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00442	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MFCOLMCK_00443	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFCOLMCK_00444	4.49e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MFCOLMCK_00445	1.49e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MFCOLMCK_00446	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MFCOLMCK_00447	1.18e-190	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MFCOLMCK_00448	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MFCOLMCK_00449	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
MFCOLMCK_00451	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFCOLMCK_00452	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MFCOLMCK_00453	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MFCOLMCK_00454	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MFCOLMCK_00455	1.25e-143	-	-	-	K	-	-	-	WHG domain
MFCOLMCK_00456	2.63e-50	-	-	-	-	-	-	-	-
MFCOLMCK_00457	2.32e-47	-	-	-	-	-	-	-	-
MFCOLMCK_00458	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFCOLMCK_00459	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MFCOLMCK_00460	1.11e-177	-	-	-	-	-	-	-	-
MFCOLMCK_00461	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00462	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00463	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MFCOLMCK_00464	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MFCOLMCK_00465	2.45e-164	-	-	-	-	-	-	-	-
MFCOLMCK_00466	6.89e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MFCOLMCK_00467	2.23e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MFCOLMCK_00468	4.67e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MFCOLMCK_00469	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MFCOLMCK_00470	3.75e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFCOLMCK_00471	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MFCOLMCK_00472	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00473	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00474	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MFCOLMCK_00475	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
MFCOLMCK_00476	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MFCOLMCK_00477	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MFCOLMCK_00478	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MFCOLMCK_00479	3.58e-251	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MFCOLMCK_00480	2.61e-23	-	-	-	-	-	-	-	-
MFCOLMCK_00481	3.15e-121	-	-	-	S	-	-	-	membrane
MFCOLMCK_00482	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
MFCOLMCK_00483	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MFCOLMCK_00484	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MFCOLMCK_00485	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MFCOLMCK_00486	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
MFCOLMCK_00487	7.62e-223	-	-	-	-	-	-	-	-
MFCOLMCK_00488	6.74e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MFCOLMCK_00489	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MFCOLMCK_00490	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
MFCOLMCK_00495	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00496	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00497	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_00498	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MFCOLMCK_00499	2.85e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MFCOLMCK_00500	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MFCOLMCK_00501	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MFCOLMCK_00502	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MFCOLMCK_00503	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MFCOLMCK_00504	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
MFCOLMCK_00505	3.68e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MFCOLMCK_00506	4.24e-46	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MFCOLMCK_00507	1e-131	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MFCOLMCK_00508	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFCOLMCK_00509	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MFCOLMCK_00510	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
MFCOLMCK_00511	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
MFCOLMCK_00512	3.49e-283	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MFCOLMCK_00513	2.58e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
MFCOLMCK_00514	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
MFCOLMCK_00515	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MFCOLMCK_00516	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
MFCOLMCK_00519	1.02e-200	-	-	-	-	-	-	-	-
MFCOLMCK_00520	1.03e-07	-	-	-	-	-	-	-	-
MFCOLMCK_00521	5.51e-47	-	-	-	-	-	-	-	-
MFCOLMCK_00522	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MFCOLMCK_00523	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
MFCOLMCK_00524	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
MFCOLMCK_00525	1.32e-137	-	-	-	-	-	-	-	-
MFCOLMCK_00526	9.07e-143	-	-	-	-	-	-	-	-
MFCOLMCK_00527	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
MFCOLMCK_00528	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MFCOLMCK_00529	6.77e-111	-	-	-	-	-	-	-	-
MFCOLMCK_00530	1.09e-74	-	-	-	-	-	-	-	-
MFCOLMCK_00531	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
MFCOLMCK_00532	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MFCOLMCK_00533	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MFCOLMCK_00534	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFCOLMCK_00535	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFCOLMCK_00536	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFCOLMCK_00539	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MFCOLMCK_00540	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MFCOLMCK_00541	6.45e-291	-	-	-	E	-	-	-	amino acid
MFCOLMCK_00542	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MFCOLMCK_00544	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
MFCOLMCK_00545	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00546	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MFCOLMCK_00547	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MFCOLMCK_00548	1.46e-148	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MFCOLMCK_00549	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MFCOLMCK_00550	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MFCOLMCK_00551	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_00552	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00553	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MFCOLMCK_00554	1.96e-49	-	-	-	-	-	-	-	-
MFCOLMCK_00555	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MFCOLMCK_00556	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MFCOLMCK_00557	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MFCOLMCK_00558	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_00559	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFCOLMCK_00560	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFCOLMCK_00561	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MFCOLMCK_00562	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFCOLMCK_00563	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MFCOLMCK_00564	1.42e-58	-	-	-	-	-	-	-	-
MFCOLMCK_00565	5.11e-265	-	-	-	S	-	-	-	Membrane
MFCOLMCK_00566	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
MFCOLMCK_00567	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MFCOLMCK_00568	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MFCOLMCK_00569	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MFCOLMCK_00570	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MFCOLMCK_00571	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MFCOLMCK_00572	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00573	1.05e-67	-	-	-	-	-	-	-	-
MFCOLMCK_00574	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MFCOLMCK_00575	1.49e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MFCOLMCK_00576	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MFCOLMCK_00577	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
MFCOLMCK_00578	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00579	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MFCOLMCK_00580	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MFCOLMCK_00581	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MFCOLMCK_00582	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MFCOLMCK_00583	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MFCOLMCK_00584	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MFCOLMCK_00585	2.1e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MFCOLMCK_00586	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
MFCOLMCK_00587	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFCOLMCK_00588	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MFCOLMCK_00589	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MFCOLMCK_00590	6.64e-94	-	-	-	-	-	-	-	-
MFCOLMCK_00591	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MFCOLMCK_00592	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MFCOLMCK_00593	3.85e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MFCOLMCK_00594	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MFCOLMCK_00595	1.62e-104	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_00596	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MFCOLMCK_00597	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MFCOLMCK_00598	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MFCOLMCK_00599	5.05e-11	-	-	-	-	-	-	-	-
MFCOLMCK_00600	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MFCOLMCK_00602	4.06e-108	yneE	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_00603	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_00604	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_00605	2.5e-186	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MFCOLMCK_00606	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MFCOLMCK_00608	1.14e-115	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MFCOLMCK_00609	7.6e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFCOLMCK_00610	3.56e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MFCOLMCK_00611	2.65e-108	usp5	-	-	T	-	-	-	universal stress protein
MFCOLMCK_00613	1.78e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MFCOLMCK_00614	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MFCOLMCK_00615	1.91e-168	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_00616	1.29e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_00617	7.05e-103	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MFCOLMCK_00618	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MFCOLMCK_00619	3.61e-212	-	-	-	V	-	-	-	ABC transporter transmembrane region
MFCOLMCK_00620	1.26e-176	-	-	-	-	-	-	-	-
MFCOLMCK_00624	2.23e-48	-	-	-	-	-	-	-	-
MFCOLMCK_00625	5.94e-75	-	-	-	S	-	-	-	Cupredoxin-like domain
MFCOLMCK_00626	3.27e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
MFCOLMCK_00627	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MFCOLMCK_00628	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MFCOLMCK_00629	3.14e-137	-	-	-	-	-	-	-	-
MFCOLMCK_00630	1.83e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MFCOLMCK_00631	6.46e-27	-	-	-	-	-	-	-	-
MFCOLMCK_00632	3.91e-269	-	-	-	-	-	-	-	-
MFCOLMCK_00633	6.57e-175	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00634	1.14e-154	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00635	4.54e-135	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MFCOLMCK_00636	2.35e-58	-	-	-	-	-	-	-	-
MFCOLMCK_00637	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00638	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
MFCOLMCK_00639	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MFCOLMCK_00645	5.32e-80	-	-	-	KL	-	-	-	DNA methylase
MFCOLMCK_00646	1.57e-90	-	-	-	S	-	-	-	N-methyltransferase activity
MFCOLMCK_00651	1.22e-233	-	-	-	S	-	-	-	Terminase-like family
MFCOLMCK_00652	3.69e-109	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
MFCOLMCK_00653	8.99e-68	-	-	-	S	-	-	-	Phage Mu protein F like protein
MFCOLMCK_00654	9.61e-28	-	-	-	S	-	-	-	Lysin motif
MFCOLMCK_00655	9.27e-71	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
MFCOLMCK_00656	8.98e-25	-	-	-	-	-	-	-	-
MFCOLMCK_00658	4.47e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4054)
MFCOLMCK_00659	5.56e-22	-	-	-	-	-	-	-	-
MFCOLMCK_00662	8.17e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MFCOLMCK_00665	2.9e-238	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MFCOLMCK_00666	2.73e-54	-	-	-	M	-	-	-	LysM domain
MFCOLMCK_00667	9.82e-61	-	-	-	-	-	-	-	-
MFCOLMCK_00668	6.56e-128	-	-	-	-	-	-	-	-
MFCOLMCK_00669	9.53e-48	-	-	-	-	-	-	-	-
MFCOLMCK_00670	6.21e-38	-	-	-	-	-	-	-	-
MFCOLMCK_00671	3.34e-139	-	-	-	S	-	-	-	Baseplate J-like protein
MFCOLMCK_00674	1.08e-92	-	-	-	-	-	-	-	-
MFCOLMCK_00680	1.58e-09	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
MFCOLMCK_00683	1.28e-22	-	-	-	-	-	-	-	-
MFCOLMCK_00684	1.66e-36	-	-	-	-	-	-	-	-
MFCOLMCK_00685	6.1e-227	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MFCOLMCK_00688	9.44e-63	-	-	-	M	-	-	-	LysM domain protein
MFCOLMCK_00689	1.8e-36	-	-	-	M	-	-	-	LysM domain protein
MFCOLMCK_00690	3.21e-175	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MFCOLMCK_00691	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
MFCOLMCK_00692	3.48e-105	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MFCOLMCK_00693	4.27e-298	-	-	-	V	-	-	-	N-6 DNA Methylase
MFCOLMCK_00694	6.73e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_00695	1.71e-156	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MFCOLMCK_00696	7.98e-35	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFCOLMCK_00697	4.68e-25	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MFCOLMCK_00698	8.24e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MFCOLMCK_00699	7.62e-32	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFCOLMCK_00701	1.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_00702	5.85e-67	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_00704	1.54e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MFCOLMCK_00705	2.78e-45	-	-	-	-	-	-	-	-
MFCOLMCK_00707	1.95e-28	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MFCOLMCK_00709	4.7e-156	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MFCOLMCK_00711	7.33e-19	-	-	-	-	-	-	-	-
MFCOLMCK_00712	1.69e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MFCOLMCK_00713	1.86e-56	-	-	-	E	-	-	-	Pfam:DUF955
MFCOLMCK_00715	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00717	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
MFCOLMCK_00719	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
MFCOLMCK_00720	4.82e-144	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00723	2.41e-39	-	-	-	-	-	-	-	-
MFCOLMCK_00725	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MFCOLMCK_00726	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
MFCOLMCK_00727	6.43e-143	-	-	-	S	-	-	-	Fic/DOC family
MFCOLMCK_00728	1.72e-22	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MFCOLMCK_00729	2.75e-34	-	-	-	L	-	-	-	four-way junction helicase activity
MFCOLMCK_00738	8.52e-25	lysM	-	-	M	-	-	-	LysM domain
MFCOLMCK_00739	6.51e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MFCOLMCK_00743	8.83e-163	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MFCOLMCK_00748	3.24e-13	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00749	6.47e-10	-	-	-	M	-	-	-	oxidoreductase activity
MFCOLMCK_00751	3.56e-21	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MFCOLMCK_00752	3.14e-15	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00758	3.35e-09	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFCOLMCK_00759	3.46e-14	-	-	-	-	-	-	-	-
MFCOLMCK_00766	6.78e-47	-	-	-	-	-	-	-	-
MFCOLMCK_00767	1.44e-161	-	-	-	S	-	-	-	interspecies interaction between organisms
MFCOLMCK_00768	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
MFCOLMCK_00769	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
MFCOLMCK_00770	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_00771	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MFCOLMCK_00772	7.97e-156	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MFCOLMCK_00773	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
MFCOLMCK_00774	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MFCOLMCK_00775	6.95e-165	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFCOLMCK_00776	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFCOLMCK_00777	2.82e-84	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MFCOLMCK_00778	1.48e-28	axe1	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	acetyl xylan esterase
MFCOLMCK_00779	1.19e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MFCOLMCK_00780	1.1e-155	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFCOLMCK_00781	3.07e-136	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MFCOLMCK_00782	7.93e-139	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MFCOLMCK_00783	5.34e-143	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Enoyl-CoA hydratase/isomerase
MFCOLMCK_00784	1.02e-192	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MFCOLMCK_00785	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MFCOLMCK_00786	4.12e-205	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MFCOLMCK_00787	5.38e-184	-	-	-	K	-	-	-	LysR substrate binding domain
MFCOLMCK_00788	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFCOLMCK_00789	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MFCOLMCK_00790	3.28e-101	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MFCOLMCK_00791	1.22e-97	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MFCOLMCK_00794	3.85e-10	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00795	2.69e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00796	1.23e-101	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
MFCOLMCK_00797	5.99e-61	-	-	-	-	-	-	-	-
MFCOLMCK_00803	8.83e-88	-	-	-	S	-	-	-	AAA domain
MFCOLMCK_00805	1.52e-182	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MFCOLMCK_00806	4.62e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MFCOLMCK_00807	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MFCOLMCK_00820	6.57e-45	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MFCOLMCK_00821	1.49e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_00823	9.34e-231	-	-	-	L	-	-	-	N-6 DNA Methylase
MFCOLMCK_00828	2.76e-189	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MFCOLMCK_00830	1.74e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
MFCOLMCK_00831	1.12e-28	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
MFCOLMCK_00832	1.87e-220	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MFCOLMCK_00833	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MFCOLMCK_00834	5.18e-109	-	-	-	-	-	-	-	-
MFCOLMCK_00835	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MFCOLMCK_00836	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MFCOLMCK_00837	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MFCOLMCK_00838	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MFCOLMCK_00839	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFCOLMCK_00840	1.69e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MFCOLMCK_00841	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MFCOLMCK_00842	5.67e-278	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
MFCOLMCK_00843	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MFCOLMCK_00844	1.64e-59	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MFCOLMCK_00845	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MFCOLMCK_00846	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MFCOLMCK_00847	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFCOLMCK_00848	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MFCOLMCK_00849	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MFCOLMCK_00850	1.14e-164	-	-	-	S	-	-	-	Fic/DOC family
MFCOLMCK_00851	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
MFCOLMCK_00852	4.65e-184	-	-	-	D	-	-	-	AAA domain
MFCOLMCK_00853	1.17e-38	-	-	-	-	-	-	-	-
MFCOLMCK_00854	4.87e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFCOLMCK_00855	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
MFCOLMCK_00856	1.57e-61	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MFCOLMCK_00858	4.97e-45	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
MFCOLMCK_00859	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
MFCOLMCK_00860	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
MFCOLMCK_00861	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MFCOLMCK_00862	4.1e-34	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MFCOLMCK_00863	7.44e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_00865	3.52e-103	epsIIG	1.1.1.133	-	S	ko:K00067,ko:K07011	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Glycosyltransferase, group 2 family protein
MFCOLMCK_00866	1.81e-91	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
MFCOLMCK_00867	1.63e-52	-	-	-	M	-	-	-	Glycosyl transferase family 2
MFCOLMCK_00868	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MFCOLMCK_00869	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFCOLMCK_00870	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFCOLMCK_00871	2.47e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MFCOLMCK_00872	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MFCOLMCK_00873	1.93e-100	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
MFCOLMCK_00874	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
MFCOLMCK_00875	4.63e-32	-	-	-	-	-	-	-	-
MFCOLMCK_00880	2.72e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MFCOLMCK_00882	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MFCOLMCK_00883	2.52e-131	-	-	-	L	-	-	-	Integrase
MFCOLMCK_00884	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MFCOLMCK_00885	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MFCOLMCK_00886	2.55e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00887	6.1e-186	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_00888	0.0	-	-	-	L	-	-	-	Transposase DDE domain
MFCOLMCK_00889	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
MFCOLMCK_00890	2.75e-304	-	-	-	L	-	-	-	Transposase DDE domain
MFCOLMCK_00891	9.13e-157	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MFCOLMCK_00892	1.08e-229	-	-	-	L	-	-	-	DDE superfamily endonuclease
MFCOLMCK_00893	1.3e-117	ydiM	-	-	G	-	-	-	Major facilitator superfamily
MFCOLMCK_00894	6.09e-233	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MFCOLMCK_00895	7.88e-59	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MFCOLMCK_00897	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MFCOLMCK_00898	6.55e-97	-	-	-	-	-	-	-	-
MFCOLMCK_00899	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MFCOLMCK_00901	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MFCOLMCK_00902	3.61e-60	-	-	-	-	-	-	-	-
MFCOLMCK_00903	1.56e-217	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFCOLMCK_00904	2.09e-105	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MFCOLMCK_00905	2.14e-103	-	-	-	-	-	-	-	-
MFCOLMCK_00907	2.85e-54	-	-	-	-	-	-	-	-
MFCOLMCK_00908	8.49e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MFCOLMCK_00910	5.32e-190	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MFCOLMCK_00912	6.87e-27	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MFCOLMCK_00913	1.1e-137	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00914	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MFCOLMCK_00915	1.21e-40	-	-	-	-	-	-	-	-
MFCOLMCK_00916	8.28e-28	-	-	-	-	-	-	-	-
MFCOLMCK_00917	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MFCOLMCK_00918	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MFCOLMCK_00919	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MFCOLMCK_00920	3.68e-162	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00922	1.47e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFCOLMCK_00923	8.93e-233	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MFCOLMCK_00924	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MFCOLMCK_00925	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MFCOLMCK_00926	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MFCOLMCK_00927	1.98e-168	-	-	-	-	-	-	-	-
MFCOLMCK_00928	1.72e-149	-	-	-	-	-	-	-	-
MFCOLMCK_00929	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFCOLMCK_00930	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
MFCOLMCK_00931	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MFCOLMCK_00932	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFCOLMCK_00933	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MFCOLMCK_00934	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MFCOLMCK_00935	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFCOLMCK_00936	9.39e-71	-	-	-	-	-	-	-	-
MFCOLMCK_00938	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MFCOLMCK_00939	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MFCOLMCK_00940	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_00941	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_00942	1.08e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFCOLMCK_00943	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFCOLMCK_00944	6.71e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFCOLMCK_00945	6.08e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MFCOLMCK_00946	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MFCOLMCK_00947	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MFCOLMCK_00948	8.35e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MFCOLMCK_00949	2.02e-38	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFCOLMCK_00950	1.67e-143	-	-	-	-	-	-	-	-
MFCOLMCK_00952	1.66e-143	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MFCOLMCK_00953	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MFCOLMCK_00954	4.29e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MFCOLMCK_00955	1.08e-133	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MFCOLMCK_00956	1.28e-172	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MFCOLMCK_00957	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MFCOLMCK_00958	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFCOLMCK_00959	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MFCOLMCK_00960	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFCOLMCK_00961	2.56e-193	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFCOLMCK_00962	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MFCOLMCK_00963	2.91e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MFCOLMCK_00964	1.04e-306	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFCOLMCK_00965	5.52e-113	-	-	-	-	-	-	-	-
MFCOLMCK_00966	0.0	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_00967	1.55e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFCOLMCK_00968	2.45e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MFCOLMCK_00969	1.37e-219	-	-	-	GK	-	-	-	ROK family
MFCOLMCK_00970	2.53e-56	-	-	-	-	-	-	-	-
MFCOLMCK_00971	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MFCOLMCK_00972	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MFCOLMCK_00973	1.28e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFCOLMCK_00974	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFCOLMCK_00975	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFCOLMCK_00976	7.28e-97	-	-	-	K	-	-	-	acetyltransferase
MFCOLMCK_00977	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MFCOLMCK_00978	7.84e-201	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MFCOLMCK_00979	1.08e-289	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MFCOLMCK_00980	7.92e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFCOLMCK_00981	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
MFCOLMCK_00982	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MFCOLMCK_00984	1.89e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MFCOLMCK_00985	6.79e-270	-	-	-	M	-	-	-	Rib/alpha-like repeat
MFCOLMCK_00986	2.07e-178	-	-	-	P	-	-	-	Voltage gated chloride channel
MFCOLMCK_00987	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MFCOLMCK_00988	8.68e-69	-	-	-	-	-	-	-	-
MFCOLMCK_00989	1.17e-56	-	-	-	-	-	-	-	-
MFCOLMCK_00990	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFCOLMCK_00991	0.0	-	-	-	E	-	-	-	amino acid
MFCOLMCK_00992	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MFCOLMCK_00993	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MFCOLMCK_00994	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MFCOLMCK_00995	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFCOLMCK_00996	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFCOLMCK_00997	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFCOLMCK_00998	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFCOLMCK_00999	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
MFCOLMCK_01000	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MFCOLMCK_01001	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFCOLMCK_01002	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFCOLMCK_01003	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
MFCOLMCK_01004	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MFCOLMCK_01005	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MFCOLMCK_01006	2.75e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFCOLMCK_01007	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFCOLMCK_01008	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFCOLMCK_01009	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFCOLMCK_01010	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MFCOLMCK_01011	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
MFCOLMCK_01014	1.71e-91	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MFCOLMCK_01015	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MFCOLMCK_01016	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFCOLMCK_01017	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFCOLMCK_01018	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MFCOLMCK_01019	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFCOLMCK_01020	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFCOLMCK_01021	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFCOLMCK_01022	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MFCOLMCK_01023	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFCOLMCK_01024	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MFCOLMCK_01025	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFCOLMCK_01026	3.3e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFCOLMCK_01027	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFCOLMCK_01028	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFCOLMCK_01029	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFCOLMCK_01030	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFCOLMCK_01031	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MFCOLMCK_01032	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFCOLMCK_01033	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFCOLMCK_01034	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFCOLMCK_01035	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFCOLMCK_01036	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFCOLMCK_01037	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFCOLMCK_01038	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFCOLMCK_01039	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFCOLMCK_01040	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFCOLMCK_01041	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MFCOLMCK_01042	2.86e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MFCOLMCK_01043	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFCOLMCK_01044	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFCOLMCK_01045	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFCOLMCK_01046	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MFCOLMCK_01047	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFCOLMCK_01048	3.14e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFCOLMCK_01049	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFCOLMCK_01050	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MFCOLMCK_01051	5.91e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFCOLMCK_01052	1.58e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFCOLMCK_01053	1.53e-175	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFCOLMCK_01054	5.69e-190	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFCOLMCK_01055	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFCOLMCK_01056	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MFCOLMCK_01057	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
MFCOLMCK_01058	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MFCOLMCK_01059	1.56e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MFCOLMCK_01060	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MFCOLMCK_01061	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MFCOLMCK_01062	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MFCOLMCK_01063	2.42e-33	-	-	-	-	-	-	-	-
MFCOLMCK_01064	9.82e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFCOLMCK_01065	2.32e-234	-	-	-	S	-	-	-	AAA domain
MFCOLMCK_01066	8.69e-66	-	-	-	-	-	-	-	-
MFCOLMCK_01067	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MFCOLMCK_01068	1.11e-69	-	-	-	-	-	-	-	-
MFCOLMCK_01069	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MFCOLMCK_01070	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFCOLMCK_01071	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFCOLMCK_01072	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MFCOLMCK_01073	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFCOLMCK_01074	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFCOLMCK_01075	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MFCOLMCK_01076	1.19e-45	-	-	-	-	-	-	-	-
MFCOLMCK_01077	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MFCOLMCK_01078	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFCOLMCK_01079	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFCOLMCK_01080	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MFCOLMCK_01081	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFCOLMCK_01082	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFCOLMCK_01083	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MFCOLMCK_01084	1.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MFCOLMCK_01085	2.48e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MFCOLMCK_01086	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFCOLMCK_01087	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFCOLMCK_01088	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MFCOLMCK_01089	1.61e-117	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_01091	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFCOLMCK_01092	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFCOLMCK_01093	9.32e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MFCOLMCK_01094	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MFCOLMCK_01095	6.15e-36	-	-	-	-	-	-	-	-
MFCOLMCK_01096	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFCOLMCK_01097	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFCOLMCK_01098	1.12e-136	-	-	-	M	-	-	-	family 8
MFCOLMCK_01099	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
MFCOLMCK_01100	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFCOLMCK_01101	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFCOLMCK_01102	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MFCOLMCK_01103	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFCOLMCK_01104	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MFCOLMCK_01105	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MFCOLMCK_01106	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MFCOLMCK_01107	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFCOLMCK_01108	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MFCOLMCK_01109	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MFCOLMCK_01110	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MFCOLMCK_01111	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MFCOLMCK_01112	5.79e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFCOLMCK_01113	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MFCOLMCK_01114	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MFCOLMCK_01115	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MFCOLMCK_01116	9.48e-31	-	-	-	-	-	-	-	-
MFCOLMCK_01117	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MFCOLMCK_01118	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MFCOLMCK_01119	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MFCOLMCK_01120	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MFCOLMCK_01121	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFCOLMCK_01122	1.94e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MFCOLMCK_01123	2.36e-217	degV1	-	-	S	-	-	-	DegV family
MFCOLMCK_01124	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MFCOLMCK_01125	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MFCOLMCK_01126	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_01127	2.14e-231	-	-	-	M	-	-	-	CHAP domain
MFCOLMCK_01128	2.79e-102	-	-	-	-	-	-	-	-
MFCOLMCK_01129	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFCOLMCK_01130	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFCOLMCK_01131	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFCOLMCK_01132	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFCOLMCK_01133	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFCOLMCK_01134	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFCOLMCK_01135	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MFCOLMCK_01136	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFCOLMCK_01137	6.15e-268	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFCOLMCK_01138	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MFCOLMCK_01139	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFCOLMCK_01140	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFCOLMCK_01141	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MFCOLMCK_01142	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFCOLMCK_01143	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MFCOLMCK_01144	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFCOLMCK_01145	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MFCOLMCK_01146	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFCOLMCK_01147	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MFCOLMCK_01148	4.13e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MFCOLMCK_01149	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFCOLMCK_01150	1.55e-29	-	-	-	-	-	-	-	-
MFCOLMCK_01151	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MFCOLMCK_01152	4.31e-175	-	-	-	-	-	-	-	-
MFCOLMCK_01153	9.1e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MFCOLMCK_01154	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MFCOLMCK_01155	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFCOLMCK_01156	3.09e-71	-	-	-	-	-	-	-	-
MFCOLMCK_01157	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MFCOLMCK_01158	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MFCOLMCK_01159	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MFCOLMCK_01160	9.89e-74	-	-	-	-	-	-	-	-
MFCOLMCK_01161	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MFCOLMCK_01162	4.25e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MFCOLMCK_01163	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFCOLMCK_01164	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MFCOLMCK_01165	6.9e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MFCOLMCK_01166	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MFCOLMCK_01194	2e-285	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MFCOLMCK_01195	3.68e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MFCOLMCK_01196	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFCOLMCK_01197	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFCOLMCK_01198	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MFCOLMCK_01199	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFCOLMCK_01200	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MFCOLMCK_01202	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MFCOLMCK_01203	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MFCOLMCK_01204	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MFCOLMCK_01205	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MFCOLMCK_01206	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_01207	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MFCOLMCK_01208	4.62e-308	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MFCOLMCK_01209	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MFCOLMCK_01210	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MFCOLMCK_01211	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFCOLMCK_01212	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MFCOLMCK_01213	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MFCOLMCK_01214	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01215	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MFCOLMCK_01216	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MFCOLMCK_01217	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MFCOLMCK_01218	3.36e-42	-	-	-	-	-	-	-	-
MFCOLMCK_01219	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MFCOLMCK_01220	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_01221	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MFCOLMCK_01222	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MFCOLMCK_01223	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
MFCOLMCK_01224	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
MFCOLMCK_01225	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
MFCOLMCK_01226	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MFCOLMCK_01227	7.82e-80	-	-	-	-	-	-	-	-
MFCOLMCK_01228	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MFCOLMCK_01229	6.58e-175	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MFCOLMCK_01231	3.31e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MFCOLMCK_01232	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MFCOLMCK_01233	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MFCOLMCK_01235	1.04e-41	-	-	-	-	-	-	-	-
MFCOLMCK_01236	1.32e-218	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MFCOLMCK_01237	1.25e-17	-	-	-	-	-	-	-	-
MFCOLMCK_01238	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
MFCOLMCK_01239	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MFCOLMCK_01240	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01241	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01242	1.47e-107	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01243	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
MFCOLMCK_01244	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
MFCOLMCK_01245	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MFCOLMCK_01246	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
MFCOLMCK_01247	7.75e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MFCOLMCK_01248	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MFCOLMCK_01250	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MFCOLMCK_01252	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MFCOLMCK_01253	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MFCOLMCK_01254	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MFCOLMCK_01255	1.43e-186	-	-	-	K	-	-	-	SIS domain
MFCOLMCK_01256	1.76e-65	slpX	-	-	S	-	-	-	SLAP domain
MFCOLMCK_01257	3.98e-210	slpX	-	-	S	-	-	-	SLAP domain
MFCOLMCK_01258	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
MFCOLMCK_01259	1.18e-13	-	-	-	-	-	-	-	-
MFCOLMCK_01260	4.41e-305	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MFCOLMCK_01263	7.83e-303	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_01264	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MFCOLMCK_01265	7.24e-231	-	-	-	-	-	-	-	-
MFCOLMCK_01266	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MFCOLMCK_01267	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MFCOLMCK_01268	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFCOLMCK_01269	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
MFCOLMCK_01270	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFCOLMCK_01271	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFCOLMCK_01272	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MFCOLMCK_01273	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MFCOLMCK_01274	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFCOLMCK_01275	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MFCOLMCK_01276	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MFCOLMCK_01277	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MFCOLMCK_01279	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MFCOLMCK_01280	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MFCOLMCK_01281	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFCOLMCK_01282	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
MFCOLMCK_01283	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFCOLMCK_01284	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFCOLMCK_01285	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFCOLMCK_01286	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MFCOLMCK_01287	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MFCOLMCK_01288	1.46e-75	-	-	-	-	-	-	-	-
MFCOLMCK_01289	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MFCOLMCK_01290	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MFCOLMCK_01291	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_01292	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFCOLMCK_01293	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_01298	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_01299	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MFCOLMCK_01300	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MFCOLMCK_01301	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MFCOLMCK_01302	1.53e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_01303	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_01304	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MFCOLMCK_01305	8.97e-47	-	-	-	-	-	-	-	-
MFCOLMCK_01306	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MFCOLMCK_01307	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MFCOLMCK_01308	1.02e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFCOLMCK_01309	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_01310	1.06e-195	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MFCOLMCK_01311	1.12e-168	-	-	-	V	-	-	-	ABC transporter transmembrane region
MFCOLMCK_01312	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MFCOLMCK_01313	3.81e-18	-	-	-	S	-	-	-	CsbD-like
MFCOLMCK_01314	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
MFCOLMCK_01315	2.33e-230	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MFCOLMCK_01316	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MFCOLMCK_01317	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
MFCOLMCK_01318	1.53e-176	-	-	-	-	-	-	-	-
MFCOLMCK_01319	1.11e-256	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MFCOLMCK_01320	3.97e-33	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MFCOLMCK_01321	3.97e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MFCOLMCK_01322	1.07e-165	-	-	-	F	-	-	-	glutamine amidotransferase
MFCOLMCK_01323	2.05e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MFCOLMCK_01324	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MFCOLMCK_01325	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_01326	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MFCOLMCK_01327	1.72e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MFCOLMCK_01328	8.41e-314	-	-	-	G	-	-	-	MFS/sugar transport protein
MFCOLMCK_01329	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MFCOLMCK_01330	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MFCOLMCK_01331	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_01332	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_01333	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_01334	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_01335	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MFCOLMCK_01336	2.09e-110	-	-	-	-	-	-	-	-
MFCOLMCK_01337	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MFCOLMCK_01338	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MFCOLMCK_01339	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MFCOLMCK_01340	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFCOLMCK_01341	1.82e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MFCOLMCK_01342	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MFCOLMCK_01343	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MFCOLMCK_01344	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MFCOLMCK_01345	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MFCOLMCK_01346	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
MFCOLMCK_01347	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MFCOLMCK_01348	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MFCOLMCK_01349	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
MFCOLMCK_01350	7.44e-189	-	-	-	S	-	-	-	hydrolase
MFCOLMCK_01351	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MFCOLMCK_01352	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MFCOLMCK_01353	1.52e-103	-	-	-	-	-	-	-	-
MFCOLMCK_01354	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFCOLMCK_01355	1.76e-52	-	-	-	-	-	-	-	-
MFCOLMCK_01356	2.14e-154	-	-	-	C	-	-	-	nitroreductase
MFCOLMCK_01357	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MFCOLMCK_01358	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MFCOLMCK_01359	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MFCOLMCK_01360	1.42e-113	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MFCOLMCK_01361	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MFCOLMCK_01362	6.74e-269	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MFCOLMCK_01363	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MFCOLMCK_01364	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
MFCOLMCK_01365	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MFCOLMCK_01366	3.55e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MFCOLMCK_01367	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MFCOLMCK_01368	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01370	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFCOLMCK_01371	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MFCOLMCK_01372	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MFCOLMCK_01373	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MFCOLMCK_01374	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MFCOLMCK_01375	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MFCOLMCK_01376	1.22e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MFCOLMCK_01377	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MFCOLMCK_01378	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
MFCOLMCK_01379	1.16e-78	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFCOLMCK_01380	6.58e-293	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MFCOLMCK_01381	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MFCOLMCK_01382	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MFCOLMCK_01383	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MFCOLMCK_01384	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MFCOLMCK_01385	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MFCOLMCK_01386	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MFCOLMCK_01387	1.01e-22	-	-	-	L	-	-	-	Transposase
MFCOLMCK_01388	7.51e-16	-	-	-	L	-	-	-	Transposase
MFCOLMCK_01389	3.76e-18	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_01390	7.74e-61	-	-	-	-	-	-	-	-
MFCOLMCK_01391	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MFCOLMCK_01392	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MFCOLMCK_01393	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFCOLMCK_01394	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MFCOLMCK_01395	1.74e-111	-	-	-	-	-	-	-	-
MFCOLMCK_01396	7.76e-98	-	-	-	-	-	-	-	-
MFCOLMCK_01397	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MFCOLMCK_01398	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MFCOLMCK_01399	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MFCOLMCK_01400	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MFCOLMCK_01401	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MFCOLMCK_01402	2.6e-37	-	-	-	-	-	-	-	-
MFCOLMCK_01403	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MFCOLMCK_01404	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFCOLMCK_01405	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFCOLMCK_01406	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MFCOLMCK_01407	3.63e-118	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MFCOLMCK_01408	2.98e-56	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MFCOLMCK_01409	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MFCOLMCK_01410	2.44e-143	-	-	-	S	-	-	-	CYTH
MFCOLMCK_01411	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MFCOLMCK_01412	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFCOLMCK_01413	9.29e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MFCOLMCK_01414	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MFCOLMCK_01415	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
MFCOLMCK_01416	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MFCOLMCK_01417	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MFCOLMCK_01418	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MFCOLMCK_01419	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFCOLMCK_01420	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MFCOLMCK_01421	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MFCOLMCK_01422	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MFCOLMCK_01423	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
MFCOLMCK_01424	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MFCOLMCK_01425	6.59e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MFCOLMCK_01426	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFCOLMCK_01427	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFCOLMCK_01428	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MFCOLMCK_01429	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MFCOLMCK_01430	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MFCOLMCK_01431	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MFCOLMCK_01432	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MFCOLMCK_01433	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFCOLMCK_01434	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFCOLMCK_01435	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFCOLMCK_01436	8.33e-27	-	-	-	-	-	-	-	-
MFCOLMCK_01437	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFCOLMCK_01438	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFCOLMCK_01439	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MFCOLMCK_01440	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFCOLMCK_01441	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MFCOLMCK_01442	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFCOLMCK_01443	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFCOLMCK_01444	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MFCOLMCK_01445	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MFCOLMCK_01446	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MFCOLMCK_01447	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MFCOLMCK_01448	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFCOLMCK_01449	0.0	-	-	-	S	-	-	-	SH3-like domain
MFCOLMCK_01450	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_01451	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MFCOLMCK_01452	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MFCOLMCK_01453	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MFCOLMCK_01454	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MFCOLMCK_01455	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MFCOLMCK_01456	0.0	ycaM	-	-	E	-	-	-	amino acid
MFCOLMCK_01457	0.0	-	-	-	-	-	-	-	-
MFCOLMCK_01459	9.53e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MFCOLMCK_01460	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFCOLMCK_01461	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MFCOLMCK_01462	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFCOLMCK_01463	4.81e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MFCOLMCK_01464	3.07e-124	-	-	-	-	-	-	-	-
MFCOLMCK_01465	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MFCOLMCK_01466	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFCOLMCK_01467	4.48e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MFCOLMCK_01468	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MFCOLMCK_01469	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MFCOLMCK_01470	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MFCOLMCK_01471	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MFCOLMCK_01472	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_01473	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_01474	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MFCOLMCK_01475	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFCOLMCK_01476	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
MFCOLMCK_01477	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFCOLMCK_01478	8.04e-190	-	-	-	S	-	-	-	hydrolase
MFCOLMCK_01479	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MFCOLMCK_01480	2.85e-153	-	-	-	-	-	-	-	-
MFCOLMCK_01481	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFCOLMCK_01482	2.52e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MFCOLMCK_01483	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MFCOLMCK_01484	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_01485	4.42e-75	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_01486	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01487	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MFCOLMCK_01488	1.74e-60	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
MFCOLMCK_01489	3.06e-202	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MFCOLMCK_01490	4.38e-150	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MFCOLMCK_01494	5.75e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_01495	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MFCOLMCK_01496	4.11e-44	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
MFCOLMCK_01497	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
MFCOLMCK_01498	1.67e-136	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
MFCOLMCK_01499	2.64e-46	-	-	-	-	-	-	-	-
MFCOLMCK_01500	1.96e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
MFCOLMCK_01501	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFCOLMCK_01503	0.0	-	-	-	E	-	-	-	Amino acid permease
MFCOLMCK_01504	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
MFCOLMCK_01505	4.31e-204	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MFCOLMCK_01507	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFCOLMCK_01508	1.49e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MFCOLMCK_01509	2.33e-120	-	-	-	S	-	-	-	VanZ like family
MFCOLMCK_01510	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MFCOLMCK_01511	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MFCOLMCK_01512	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MFCOLMCK_01513	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MFCOLMCK_01514	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MFCOLMCK_01515	1.68e-55	-	-	-	-	-	-	-	-
MFCOLMCK_01516	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MFCOLMCK_01517	3.69e-30	-	-	-	-	-	-	-	-
MFCOLMCK_01518	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MFCOLMCK_01519	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFCOLMCK_01521	2.26e-188	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MFCOLMCK_01523	1.11e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MFCOLMCK_01524	3.11e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_01525	2.62e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
MFCOLMCK_01527	2.13e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
MFCOLMCK_01529	1e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MFCOLMCK_01531	3e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MFCOLMCK_01532	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MFCOLMCK_01533	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MFCOLMCK_01534	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
MFCOLMCK_01535	1.97e-170	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MFCOLMCK_01536	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MFCOLMCK_01537	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFCOLMCK_01538	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
MFCOLMCK_01539	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MFCOLMCK_01540	4.63e-274	-	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_01541	3.94e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_01544	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MFCOLMCK_01545	9.98e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MFCOLMCK_01546	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFCOLMCK_01547	2.93e-197	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFCOLMCK_01548	1.36e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFCOLMCK_01549	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFCOLMCK_01550	1.01e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MFCOLMCK_01551	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFCOLMCK_01552	2.57e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFCOLMCK_01553	3.24e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFCOLMCK_01554	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFCOLMCK_01555	1.04e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFCOLMCK_01556	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFCOLMCK_01557	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MFCOLMCK_01558	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MFCOLMCK_01559	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MFCOLMCK_01560	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MFCOLMCK_01561	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MFCOLMCK_01562	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MFCOLMCK_01563	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
MFCOLMCK_01564	1.35e-56	-	-	-	-	-	-	-	-
MFCOLMCK_01565	5.98e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MFCOLMCK_01566	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MFCOLMCK_01567	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFCOLMCK_01568	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFCOLMCK_01569	1.32e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MFCOLMCK_01570	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFCOLMCK_01571	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MFCOLMCK_01572	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MFCOLMCK_01573	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MFCOLMCK_01574	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
MFCOLMCK_01575	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MFCOLMCK_01576	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MFCOLMCK_01577	8.53e-59	-	-	-	-	-	-	-	-
MFCOLMCK_01578	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MFCOLMCK_01579	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MFCOLMCK_01580	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MFCOLMCK_01581	2.91e-67	-	-	-	-	-	-	-	-
MFCOLMCK_01582	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFCOLMCK_01583	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MFCOLMCK_01584	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MFCOLMCK_01585	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MFCOLMCK_01586	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MFCOLMCK_01587	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MFCOLMCK_01588	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MFCOLMCK_01589	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MFCOLMCK_01590	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MFCOLMCK_01591	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MFCOLMCK_01592	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFCOLMCK_01593	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MFCOLMCK_01594	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MFCOLMCK_01595	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFCOLMCK_01596	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFCOLMCK_01597	7.84e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFCOLMCK_01598	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFCOLMCK_01599	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFCOLMCK_01600	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFCOLMCK_01601	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFCOLMCK_01602	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MFCOLMCK_01603	1.63e-191	ylmH	-	-	S	-	-	-	S4 domain protein
MFCOLMCK_01604	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MFCOLMCK_01605	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFCOLMCK_01606	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MFCOLMCK_01607	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MFCOLMCK_01608	1.22e-55	-	-	-	-	-	-	-	-
MFCOLMCK_01609	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFCOLMCK_01610	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MFCOLMCK_01611	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MFCOLMCK_01612	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFCOLMCK_01613	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MFCOLMCK_01614	2.31e-148	-	-	-	S	-	-	-	repeat protein
MFCOLMCK_01615	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFCOLMCK_01616	0.0	-	-	-	L	-	-	-	Nuclease-related domain
MFCOLMCK_01617	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MFCOLMCK_01618	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFCOLMCK_01619	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MFCOLMCK_01620	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFCOLMCK_01621	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MFCOLMCK_01622	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MFCOLMCK_01623	4.05e-70	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MFCOLMCK_01624	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MFCOLMCK_01625	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFCOLMCK_01626	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MFCOLMCK_01627	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MFCOLMCK_01628	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MFCOLMCK_01629	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MFCOLMCK_01630	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MFCOLMCK_01631	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFCOLMCK_01632	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFCOLMCK_01633	5.43e-191	-	-	-	-	-	-	-	-
MFCOLMCK_01634	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFCOLMCK_01635	2.56e-291	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFCOLMCK_01636	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFCOLMCK_01637	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MFCOLMCK_01638	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
MFCOLMCK_01639	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
MFCOLMCK_01640	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFCOLMCK_01641	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MFCOLMCK_01642	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFCOLMCK_01643	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFCOLMCK_01644	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFCOLMCK_01645	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFCOLMCK_01646	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFCOLMCK_01647	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MFCOLMCK_01648	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFCOLMCK_01649	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_01650	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MFCOLMCK_01651	1.83e-54	-	-	-	C	-	-	-	FMN_bind
MFCOLMCK_01652	4.49e-108	-	-	-	-	-	-	-	-
MFCOLMCK_01653	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MFCOLMCK_01654	2.06e-111	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MFCOLMCK_01655	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01656	4.65e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MFCOLMCK_01657	2.19e-73	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MFCOLMCK_01658	7.7e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
MFCOLMCK_01659	6.51e-291	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_01660	5.06e-13	-	-	-	K	-	-	-	FCD
MFCOLMCK_01661	1.45e-34	-	-	-	K	-	-	-	FCD
MFCOLMCK_01662	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MFCOLMCK_01663	5.93e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MFCOLMCK_01664	1.33e-92	-	-	-	-	-	-	-	-
MFCOLMCK_01665	4.06e-88	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01666	4.23e-46	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_01667	1.64e-215	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01668	2.73e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
MFCOLMCK_01669	5.89e-303	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01670	2.15e-36	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01671	2.3e-169	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MFCOLMCK_01672	4.22e-288	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01673	4.06e-39	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFCOLMCK_01674	1.31e-56	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01675	3.9e-139	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01676	1.4e-105	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MFCOLMCK_01677	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
MFCOLMCK_01678	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MFCOLMCK_01680	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
MFCOLMCK_01682	3.17e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MFCOLMCK_01683	2.09e-13	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MFCOLMCK_01684	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
MFCOLMCK_01685	3.87e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MFCOLMCK_01686	3.73e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MFCOLMCK_01687	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFCOLMCK_01688	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MFCOLMCK_01689	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
MFCOLMCK_01690	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MFCOLMCK_01692	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MFCOLMCK_01693	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MFCOLMCK_01694	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
MFCOLMCK_01695	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
MFCOLMCK_01696	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MFCOLMCK_01697	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MFCOLMCK_01698	8.44e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MFCOLMCK_01699	1.86e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MFCOLMCK_01700	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MFCOLMCK_01701	1.32e-114	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFCOLMCK_01702	1.15e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFCOLMCK_01703	1.53e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MFCOLMCK_01704	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MFCOLMCK_01705	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFCOLMCK_01707	1.5e-176	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_01708	2.75e-72	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MFCOLMCK_01709	8.41e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MFCOLMCK_01710	2.25e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MFCOLMCK_01711	6.44e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFCOLMCK_01712	5.75e-152	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MFCOLMCK_01713	2.94e-97	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MFCOLMCK_01714	6.21e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MFCOLMCK_01715	8.09e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MFCOLMCK_01716	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MFCOLMCK_01717	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFCOLMCK_01720	2.81e-76	-	-	-	EGP	-	-	-	Major Facilitator
MFCOLMCK_01721	4.45e-156	rbtT	-	-	P	ko:K13021	-	ko00000,ko02000	Major Facilitator Superfamily
MFCOLMCK_01722	5.25e-258	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MFCOLMCK_01723	4.6e-113	-	-	-	K	-	-	-	GNAT family
MFCOLMCK_01724	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MFCOLMCK_01726	2.46e-48	-	-	-	-	-	-	-	-
MFCOLMCK_01727	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
MFCOLMCK_01728	1.58e-10	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_01729	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_01730	1.8e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MFCOLMCK_01731	2.99e-230	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFCOLMCK_01732	7.89e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFCOLMCK_01733	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MFCOLMCK_01734	2.57e-223	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MFCOLMCK_01735	2.16e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MFCOLMCK_01736	3.87e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFCOLMCK_01737	3.32e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_01738	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFCOLMCK_01739	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MFCOLMCK_01740	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MFCOLMCK_01741	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MFCOLMCK_01742	1.71e-128	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MFCOLMCK_01743	1.09e-148	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFCOLMCK_01744	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_01745	3e-118	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_01746	2.54e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
MFCOLMCK_01747	1.95e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MFCOLMCK_01748	2.55e-26	-	-	-	-	-	-	-	-
MFCOLMCK_01749	1.06e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MFCOLMCK_01750	2.81e-102	-	-	-	E	-	-	-	Zn peptidase
MFCOLMCK_01751	1.53e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_01752	7.61e-59	-	-	-	-	-	-	-	-
MFCOLMCK_01753	1.08e-79	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MFCOLMCK_01754	3.56e-85	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_01755	8.58e-60	-	-	-	-	-	-	-	-
MFCOLMCK_01756	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_01757	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MFCOLMCK_01758	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MFCOLMCK_01759	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MFCOLMCK_01760	7.93e-63	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MFCOLMCK_01761	5.49e-97	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MFCOLMCK_01762	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
MFCOLMCK_01763	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MFCOLMCK_01764	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MFCOLMCK_01765	3.74e-180	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MFCOLMCK_01767	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
MFCOLMCK_01768	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MFCOLMCK_01769	8.46e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MFCOLMCK_01770	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MFCOLMCK_01771	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MFCOLMCK_01772	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MFCOLMCK_01773	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MFCOLMCK_01774	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MFCOLMCK_01775	9.9e-30	-	-	-	-	-	-	-	-
MFCOLMCK_01776	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MFCOLMCK_01777	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_01778	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MFCOLMCK_01779	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MFCOLMCK_01780	7.91e-14	-	-	-	-	-	-	-	-
MFCOLMCK_01781	4.19e-59	-	-	-	-	-	-	-	-
MFCOLMCK_01782	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
MFCOLMCK_01783	9.55e-158	-	-	-	S	-	-	-	Putative threonine/serine exporter
MFCOLMCK_01784	2.82e-121	-	-	-	S	-	-	-	Putative threonine/serine exporter
MFCOLMCK_01786	5.26e-15	-	-	-	-	-	-	-	-
MFCOLMCK_01787	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFCOLMCK_01788	3e-34	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MFCOLMCK_01789	5.31e-159	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MFCOLMCK_01790	3.8e-80	-	-	-	-	-	-	-	-
MFCOLMCK_01791	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFCOLMCK_01792	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFCOLMCK_01793	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MFCOLMCK_01794	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MFCOLMCK_01795	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MFCOLMCK_01796	4.66e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFCOLMCK_01797	1.19e-43	-	-	-	S	-	-	-	reductase
MFCOLMCK_01798	2.98e-50	-	-	-	S	-	-	-	reductase
MFCOLMCK_01799	6.32e-41	-	-	-	S	-	-	-	reductase
MFCOLMCK_01800	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
MFCOLMCK_01801	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFCOLMCK_01802	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MFCOLMCK_01803	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MFCOLMCK_01804	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFCOLMCK_01805	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFCOLMCK_01806	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MFCOLMCK_01807	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFCOLMCK_01808	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MFCOLMCK_01809	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MFCOLMCK_01810	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MFCOLMCK_01811	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MFCOLMCK_01812	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MFCOLMCK_01813	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MFCOLMCK_01814	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFCOLMCK_01815	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MFCOLMCK_01816	7.01e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MFCOLMCK_01817	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MFCOLMCK_01818	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFCOLMCK_01819	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFCOLMCK_01820	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFCOLMCK_01821	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MFCOLMCK_01822	1.64e-143	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFCOLMCK_01823	1.13e-41	-	-	-	M	-	-	-	Lysin motif
MFCOLMCK_01824	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MFCOLMCK_01825	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MFCOLMCK_01826	5.45e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MFCOLMCK_01827	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFCOLMCK_01828	1.43e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MFCOLMCK_01829	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFCOLMCK_01830	2.95e-123	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MFCOLMCK_01831	1.87e-170	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MFCOLMCK_01832	1.91e-44	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MFCOLMCK_01833	1.5e-150	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
MFCOLMCK_01834	1.83e-103	-	-	-	S	-	-	-	AAA domain
MFCOLMCK_01835	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
MFCOLMCK_01836	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
MFCOLMCK_01837	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MFCOLMCK_01838	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MFCOLMCK_01839	8.49e-85	-	-	-	E	-	-	-	amino acid
MFCOLMCK_01840	6.08e-161	yagE	-	-	E	-	-	-	Amino acid permease
MFCOLMCK_01841	9.58e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MFCOLMCK_01842	3.86e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFCOLMCK_01843	4.21e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFCOLMCK_01844	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MFCOLMCK_01845	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MFCOLMCK_01846	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MFCOLMCK_01847	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
MFCOLMCK_01848	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MFCOLMCK_01849	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MFCOLMCK_01850	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFCOLMCK_01851	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFCOLMCK_01852	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MFCOLMCK_01853	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFCOLMCK_01854	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFCOLMCK_01855	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MFCOLMCK_01856	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFCOLMCK_01857	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFCOLMCK_01858	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MFCOLMCK_01859	9.11e-110	-	-	-	C	-	-	-	Aldo keto reductase
MFCOLMCK_01860	2.73e-112	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MFCOLMCK_01861	3.93e-05	-	-	-	-	-	-	-	-
MFCOLMCK_01863	1.26e-22	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
MFCOLMCK_01864	6.19e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MFCOLMCK_01871	9.97e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
MFCOLMCK_01872	3.6e-57	-	-	-	S	-	-	-	ERF superfamily
MFCOLMCK_01874	2.6e-21	ansR	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_01876	2.43e-136	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MFCOLMCK_01877	5.95e-24	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MFCOLMCK_01886	7.58e-90	-	-	-	S	-	-	-	ORF6C domain
MFCOLMCK_01888	1.72e-48	-	-	-	S	-	-	-	VRR_NUC
MFCOLMCK_01889	8.19e-173	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MFCOLMCK_01890	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFCOLMCK_01891	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFCOLMCK_01892	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MFCOLMCK_01893	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MFCOLMCK_01894	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MFCOLMCK_01895	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MFCOLMCK_01896	0.0	-	-	-	E	-	-	-	Amino acid permease
MFCOLMCK_01897	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MFCOLMCK_01898	4.97e-311	ynbB	-	-	P	-	-	-	aluminum resistance
MFCOLMCK_01899	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MFCOLMCK_01900	4.23e-46	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MFCOLMCK_01901	1.19e-85	-	-	-	-	-	-	-	-
MFCOLMCK_01902	1.67e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MFCOLMCK_01903	8.44e-65	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MFCOLMCK_01904	9.89e-112	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFCOLMCK_01905	1.98e-47	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFCOLMCK_01906	4.22e-41	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFCOLMCK_01907	2.77e-177	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MFCOLMCK_01908	1.4e-137	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MFCOLMCK_01909	2.53e-268	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFCOLMCK_01910	3.17e-67	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFCOLMCK_01911	7.28e-80	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MFCOLMCK_01912	3.44e-300	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MFCOLMCK_01913	4.9e-180	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFCOLMCK_01914	2.42e-163	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MFCOLMCK_01915	1.9e-158	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MFCOLMCK_01916	7.01e-103	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFCOLMCK_01917	2.27e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFCOLMCK_01918	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
MFCOLMCK_01920	1.2e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MFCOLMCK_01921	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MFCOLMCK_01922	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MFCOLMCK_01923	2.08e-105	-	-	-	C	-	-	-	Flavodoxin
MFCOLMCK_01924	1.1e-86	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MFCOLMCK_01925	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MFCOLMCK_01926	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MFCOLMCK_01927	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
MFCOLMCK_01928	4.87e-262	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MFCOLMCK_01929	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFCOLMCK_01930	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MFCOLMCK_01931	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_01932	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MFCOLMCK_01933	1.59e-123	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MFCOLMCK_01934	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MFCOLMCK_01935	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MFCOLMCK_01936	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MFCOLMCK_01937	1.38e-242	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
MFCOLMCK_01938	2.76e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFCOLMCK_01939	9.63e-204	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_01940	2.02e-137	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MFCOLMCK_01941	4.21e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MFCOLMCK_01942	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MFCOLMCK_01944	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MFCOLMCK_01945	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MFCOLMCK_01946	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MFCOLMCK_01948	0.0	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_01949	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MFCOLMCK_01950	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MFCOLMCK_01951	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
MFCOLMCK_01952	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MFCOLMCK_01953	2.57e-61	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MFCOLMCK_01954	2.64e-49	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
MFCOLMCK_01955	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
MFCOLMCK_01957	6.08e-42	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
MFCOLMCK_01958	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MFCOLMCK_01959	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
MFCOLMCK_01961	1.61e-70	-	-	-	-	-	-	-	-
MFCOLMCK_01962	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MFCOLMCK_01963	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFCOLMCK_01964	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MFCOLMCK_01965	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MFCOLMCK_01966	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MFCOLMCK_01967	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MFCOLMCK_01968	2.06e-88	-	-	-	-	-	-	-	-
MFCOLMCK_01969	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
MFCOLMCK_01970	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFCOLMCK_01971	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MFCOLMCK_01972	1.5e-90	-	-	-	-	-	-	-	-
MFCOLMCK_01973	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MFCOLMCK_01974	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MFCOLMCK_01975	2.66e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MFCOLMCK_01976	2.3e-36	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MFCOLMCK_01977	1.97e-10	-	-	-	L	ko:K07496	-	ko00000	Transposase
MFCOLMCK_01978	8.17e-18	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MFCOLMCK_01979	7.23e-78	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
MFCOLMCK_01980	5.91e-08	-	-	-	-	-	-	-	-
MFCOLMCK_01981	1.94e-217	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MFCOLMCK_01982	9.08e-234	-	-	-	K	-	-	-	Transcriptional regulator
MFCOLMCK_01983	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFCOLMCK_01984	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFCOLMCK_01985	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFCOLMCK_01986	0.0	snf	-	-	KL	-	-	-	domain protein
MFCOLMCK_01987	1.73e-48	-	-	-	-	-	-	-	-
MFCOLMCK_01988	1.24e-08	-	-	-	-	-	-	-	-
MFCOLMCK_01989	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
MFCOLMCK_01990	1.51e-159	-	-	-	-	-	-	-	-
MFCOLMCK_01993	9.76e-82	-	-	-	-	-	-	-	-
MFCOLMCK_01994	3.56e-47	-	-	-	-	-	-	-	-
MFCOLMCK_01995	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MFCOLMCK_01996	9.67e-104	-	-	-	-	-	-	-	-
MFCOLMCK_01997	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MFCOLMCK_01998	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MFCOLMCK_01999	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFCOLMCK_02000	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MFCOLMCK_02001	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFCOLMCK_02002	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MFCOLMCK_02003	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFCOLMCK_02004	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MFCOLMCK_02005	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MFCOLMCK_02006	1.66e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MFCOLMCK_02007	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MFCOLMCK_02008	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MFCOLMCK_02009	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MFCOLMCK_02010	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MFCOLMCK_02011	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MFCOLMCK_02012	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MFCOLMCK_02013	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFCOLMCK_02014	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MFCOLMCK_02015	9.1e-317	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MFCOLMCK_02016	4.4e-215	-	-	-	-	-	-	-	-
MFCOLMCK_02017	4.01e-184	-	-	-	-	-	-	-	-
MFCOLMCK_02018	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MFCOLMCK_02019	3.49e-36	-	-	-	-	-	-	-	-
MFCOLMCK_02020	3.85e-193	-	-	-	-	-	-	-	-
MFCOLMCK_02021	2.54e-176	-	-	-	-	-	-	-	-
MFCOLMCK_02022	1.65e-180	-	-	-	-	-	-	-	-
MFCOLMCK_02023	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MFCOLMCK_02024	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MFCOLMCK_02025	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MFCOLMCK_02026	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFCOLMCK_02027	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MFCOLMCK_02028	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MFCOLMCK_02029	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
MFCOLMCK_02030	3.66e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFCOLMCK_02031	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFCOLMCK_02032	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MFCOLMCK_02033	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MFCOLMCK_02034	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MFCOLMCK_02035	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFCOLMCK_02036	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFCOLMCK_02037	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MFCOLMCK_02038	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MFCOLMCK_02039	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MFCOLMCK_02040	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFCOLMCK_02041	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MFCOLMCK_02042	2e-149	-	-	-	S	-	-	-	Peptidase family M23
MFCOLMCK_02043	1.22e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFCOLMCK_02045	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFCOLMCK_02046	5.27e-45	-	-	-	-	-	-	-	-
MFCOLMCK_02047	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
MFCOLMCK_02048	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MFCOLMCK_02049	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MFCOLMCK_02050	1.6e-74	-	-	-	-	-	-	-	-
MFCOLMCK_02051	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFCOLMCK_02052	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MFCOLMCK_02053	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MFCOLMCK_02054	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MFCOLMCK_02055	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
MFCOLMCK_02056	0.0	-	-	-	L	-	-	-	PLD-like domain
MFCOLMCK_02057	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
MFCOLMCK_02058	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
MFCOLMCK_02059	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MFCOLMCK_02060	5.51e-35	-	-	-	-	-	-	-	-
MFCOLMCK_02061	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_02062	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_02063	8.93e-108	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MFCOLMCK_02064	5.73e-153	-	-	-	-	-	-	-	-
MFCOLMCK_02065	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MFCOLMCK_02066	1.13e-126	-	-	-	-	-	-	-	-
MFCOLMCK_02067	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
MFCOLMCK_02068	4.04e-29	-	-	-	-	-	-	-	-
MFCOLMCK_02069	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
MFCOLMCK_02070	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MFCOLMCK_02071	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MFCOLMCK_02072	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFCOLMCK_02073	2.4e-297	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MFCOLMCK_02074	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MFCOLMCK_02075	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MFCOLMCK_02076	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
MFCOLMCK_02077	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MFCOLMCK_02078	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MFCOLMCK_02079	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFCOLMCK_02080	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MFCOLMCK_02081	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MFCOLMCK_02082	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFCOLMCK_02083	6.95e-50	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MFCOLMCK_02084	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFCOLMCK_02085	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MFCOLMCK_02086	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFCOLMCK_02087	6.02e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFCOLMCK_02088	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MFCOLMCK_02089	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFCOLMCK_02090	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFCOLMCK_02091	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFCOLMCK_02092	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
MFCOLMCK_02093	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MFCOLMCK_02094	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MFCOLMCK_02095	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MFCOLMCK_02096	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFCOLMCK_02097	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFCOLMCK_02098	1.83e-253	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MFCOLMCK_02099	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MFCOLMCK_02100	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFCOLMCK_02101	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFCOLMCK_02102	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MFCOLMCK_02103	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFCOLMCK_02104	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MFCOLMCK_02105	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MFCOLMCK_02106	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MFCOLMCK_02107	8.61e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MFCOLMCK_02108	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MFCOLMCK_02109	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MFCOLMCK_02110	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MFCOLMCK_02111	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MFCOLMCK_02112	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
MFCOLMCK_02113	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFCOLMCK_02114	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MFCOLMCK_02115	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MFCOLMCK_02116	4.96e-270	-	-	-	S	-	-	-	SLAP domain
MFCOLMCK_02117	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFCOLMCK_02118	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MFCOLMCK_02119	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFCOLMCK_02120	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MFCOLMCK_02121	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFCOLMCK_02122	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFCOLMCK_02123	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MFCOLMCK_02124	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MFCOLMCK_02125	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MFCOLMCK_02126	2.1e-31	-	-	-	-	-	-	-	-
MFCOLMCK_02127	1.69e-06	-	-	-	-	-	-	-	-
MFCOLMCK_02128	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MFCOLMCK_02129	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFCOLMCK_02130	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MFCOLMCK_02131	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFCOLMCK_02132	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_02133	2.46e-302	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_02134	3.35e-55	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MFCOLMCK_02135	3.74e-182	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MFCOLMCK_02136	7.92e-221	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MFCOLMCK_02137	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MFCOLMCK_02138	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MFCOLMCK_02139	7.32e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFCOLMCK_02140	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFCOLMCK_02141	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFCOLMCK_02142	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MFCOLMCK_02143	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MFCOLMCK_02144	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MFCOLMCK_02146	8.02e-127	-	-	-	M	-	-	-	hydrolase, family 25
MFCOLMCK_02147	6.5e-51	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MFCOLMCK_02156	5.6e-158	-	-	-	S	-	-	-	Phage minor structural protein
MFCOLMCK_02158	2.66e-131	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MFCOLMCK_02166	5.87e-67	-	-	-	S	-	-	-	Phage capsid family
MFCOLMCK_02167	4.37e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MFCOLMCK_02168	2.23e-169	-	-	-	S	-	-	-	Phage portal protein
MFCOLMCK_02170	1.82e-260	-	-	-	S	-	-	-	Phage Terminase
MFCOLMCK_02171	1.57e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MFCOLMCK_02172	6.84e-10	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MFCOLMCK_02173	1.2e-71	-	-	-	L	-	-	-	Phage terminase, small subunit
MFCOLMCK_02174	5.5e-43	-	-	-	L	-	-	-	HNH nucleases
MFCOLMCK_02179	3.85e-49	-	-	-	S	-	-	-	VRR_NUC
MFCOLMCK_02182	8.15e-29	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MFCOLMCK_02183	2.29e-41	-	-	-	-	-	-	-	-
MFCOLMCK_02184	1.1e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MFCOLMCK_02185	7.49e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MFCOLMCK_02186	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFCOLMCK_02187	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MFCOLMCK_02188	3.28e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MFCOLMCK_02189	7.82e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFCOLMCK_02190	1.27e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFCOLMCK_02191	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFCOLMCK_02192	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFCOLMCK_02193	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MFCOLMCK_02194	2.19e-100	-	-	-	S	-	-	-	ASCH
MFCOLMCK_02195	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MFCOLMCK_02196	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MFCOLMCK_02197	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MFCOLMCK_02198	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFCOLMCK_02199	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFCOLMCK_02200	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFCOLMCK_02201	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFCOLMCK_02202	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MFCOLMCK_02203	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFCOLMCK_02204	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MFCOLMCK_02205	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MFCOLMCK_02206	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MFCOLMCK_02207	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFCOLMCK_02208	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MFCOLMCK_02210	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MFCOLMCK_02211	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MFCOLMCK_02212	4.75e-199	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MFCOLMCK_02213	1.16e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MFCOLMCK_02215	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
MFCOLMCK_02216	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MFCOLMCK_02217	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_02218	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MFCOLMCK_02219	1.14e-189	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MFCOLMCK_02220	4.3e-66	-	-	-	-	-	-	-	-
MFCOLMCK_02221	8.51e-50	-	-	-	-	-	-	-	-
MFCOLMCK_02222	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
MFCOLMCK_02223	6.78e-24	-	-	-	S	-	-	-	Alpha beta hydrolase
MFCOLMCK_02224	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MFCOLMCK_02225	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MFCOLMCK_02226	8.74e-62	-	-	-	-	-	-	-	-
MFCOLMCK_02227	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MFCOLMCK_02228	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MFCOLMCK_02229	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MFCOLMCK_02230	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MFCOLMCK_02231	8.31e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFCOLMCK_02232	9.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MFCOLMCK_02233	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFCOLMCK_02234	8.81e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFCOLMCK_02235	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFCOLMCK_02236	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFCOLMCK_02237	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family