ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GGJMDCOG_00001 9.14e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GGJMDCOG_00002 8.11e-245 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GGJMDCOG_00003 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GGJMDCOG_00004 4.22e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGJMDCOG_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GGJMDCOG_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GGJMDCOG_00007 6.72e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GGJMDCOG_00008 4.83e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GGJMDCOG_00009 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GGJMDCOG_00010 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GGJMDCOG_00011 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GGJMDCOG_00012 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GGJMDCOG_00013 5.56e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
GGJMDCOG_00014 2.26e-215 degV1 - - S - - - DegV family
GGJMDCOG_00015 1.23e-170 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_00016 4.76e-213 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GGJMDCOG_00017 3.81e-18 - - - S - - - CsbD-like
GGJMDCOG_00018 2.26e-31 - - - S - - - Transglycosylase associated protein
GGJMDCOG_00019 1.37e-287 - - - I - - - Protein of unknown function (DUF2974)
GGJMDCOG_00020 3.92e-153 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GGJMDCOG_00024 0.0 - - - S - - - Fibronectin type III domain
GGJMDCOG_00025 7.03e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGJMDCOG_00027 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GGJMDCOG_00028 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GGJMDCOG_00029 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_00030 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_00032 1.13e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GGJMDCOG_00033 0.000868 - - - - - - - -
GGJMDCOG_00034 2.04e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GGJMDCOG_00035 6.6e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GGJMDCOG_00036 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GGJMDCOG_00037 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GGJMDCOG_00038 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GGJMDCOG_00039 9.9e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GGJMDCOG_00040 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GGJMDCOG_00041 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
GGJMDCOG_00042 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GGJMDCOG_00043 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
GGJMDCOG_00044 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GGJMDCOG_00045 3.09e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00046 3.41e-88 - - - - - - - -
GGJMDCOG_00047 2.52e-32 - - - - - - - -
GGJMDCOG_00048 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GGJMDCOG_00049 4.74e-107 - - - - - - - -
GGJMDCOG_00050 7.87e-30 - - - - - - - -
GGJMDCOG_00053 5.02e-180 blpT - - - - - - -
GGJMDCOG_00054 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GGJMDCOG_00055 1.85e-141 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GGJMDCOG_00056 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GGJMDCOG_00057 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GGJMDCOG_00058 1.04e-94 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GGJMDCOG_00059 6.42e-73 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GGJMDCOG_00060 1.89e-23 - - - - - - - -
GGJMDCOG_00061 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GGJMDCOG_00062 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GGJMDCOG_00063 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
GGJMDCOG_00064 4.48e-34 - - - - - - - -
GGJMDCOG_00065 1.07e-35 - - - - - - - -
GGJMDCOG_00066 1.95e-45 - - - - - - - -
GGJMDCOG_00067 6.94e-70 - - - S - - - Enterocin A Immunity
GGJMDCOG_00068 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GGJMDCOG_00069 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGJMDCOG_00070 9.28e-271 - - - T - - - His Kinase A (phosphoacceptor) domain
GGJMDCOG_00071 8.32e-157 vanR - - K - - - response regulator
GGJMDCOG_00073 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GGJMDCOG_00074 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00075 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00076 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
GGJMDCOG_00077 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GGJMDCOG_00078 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GGJMDCOG_00079 4.28e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GGJMDCOG_00080 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GGJMDCOG_00081 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GGJMDCOG_00082 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GGJMDCOG_00083 2.12e-86 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_00084 2.99e-75 cvpA - - S - - - Colicin V production protein
GGJMDCOG_00086 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GGJMDCOG_00087 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GGJMDCOG_00088 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GGJMDCOG_00089 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GGJMDCOG_00090 1.25e-143 - - - K - - - WHG domain
GGJMDCOG_00091 2.63e-50 - - - - - - - -
GGJMDCOG_00092 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GGJMDCOG_00093 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00094 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00095 1.45e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GGJMDCOG_00096 2.75e-143 - - - G - - - phosphoglycerate mutase
GGJMDCOG_00097 3.99e-180 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
GGJMDCOG_00098 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GGJMDCOG_00099 1.19e-29 - - - - - - - -
GGJMDCOG_00100 7.91e-102 - - - - - - - -
GGJMDCOG_00101 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
GGJMDCOG_00102 2.94e-250 - - - S - - - Putative peptidoglycan binding domain
GGJMDCOG_00103 2.61e-23 - - - - - - - -
GGJMDCOG_00104 1.05e-119 - - - S - - - membrane
GGJMDCOG_00105 5.3e-92 - - - K - - - LytTr DNA-binding domain
GGJMDCOG_00106 6.93e-34 - - - S - - - Sugar efflux transporter for intercellular exchange
GGJMDCOG_00107 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GGJMDCOG_00108 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GGJMDCOG_00109 2.2e-79 lysM - - M - - - LysM domain
GGJMDCOG_00110 7.62e-223 - - - - - - - -
GGJMDCOG_00111 6.74e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GGJMDCOG_00112 1.27e-58 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GGJMDCOG_00113 1.86e-114 ymdB - - S - - - Macro domain protein
GGJMDCOG_00118 4.73e-84 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_00119 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00120 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_00121 2.73e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_00122 2.85e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GGJMDCOG_00123 7.7e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GGJMDCOG_00124 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GGJMDCOG_00125 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GGJMDCOG_00126 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
GGJMDCOG_00127 4.13e-99 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GGJMDCOG_00128 9.42e-261 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGJMDCOG_00129 9.04e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
GGJMDCOG_00130 7.48e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GGJMDCOG_00131 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGJMDCOG_00132 3.66e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GGJMDCOG_00133 1.74e-248 - - - G - - - Transmembrane secretion effector
GGJMDCOG_00134 5.63e-171 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_00135 3.65e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GGJMDCOG_00136 1.83e-91 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_00137 6.69e-84 - - - L - - - RelB antitoxin
GGJMDCOG_00138 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GGJMDCOG_00139 8.6e-108 - - - M - - - NlpC/P60 family
GGJMDCOG_00142 1.02e-200 - - - - - - - -
GGJMDCOG_00143 1.03e-07 - - - - - - - -
GGJMDCOG_00144 5.51e-47 - - - - - - - -
GGJMDCOG_00145 4.48e-206 - - - EG - - - EamA-like transporter family
GGJMDCOG_00146 2.61e-208 - - - EG - - - EamA-like transporter family
GGJMDCOG_00147 3.75e-178 yicL - - EG - - - EamA-like transporter family
GGJMDCOG_00148 1.32e-137 - - - - - - - -
GGJMDCOG_00149 9.07e-143 - - - - - - - -
GGJMDCOG_00150 1.84e-238 - - - S - - - DUF218 domain
GGJMDCOG_00151 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
GGJMDCOG_00152 6.77e-111 - - - - - - - -
GGJMDCOG_00153 1.09e-74 - - - - - - - -
GGJMDCOG_00154 7.26e-35 - - - S - - - Protein conserved in bacteria
GGJMDCOG_00155 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GGJMDCOG_00156 1.01e-38 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GGJMDCOG_00157 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGJMDCOG_00158 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGJMDCOG_00159 1.35e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GGJMDCOG_00162 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
GGJMDCOG_00163 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GGJMDCOG_00164 6.45e-291 - - - E - - - amino acid
GGJMDCOG_00165 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GGJMDCOG_00167 1.95e-221 - - - V - - - HNH endonuclease
GGJMDCOG_00168 6.36e-173 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_00169 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GGJMDCOG_00170 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GGJMDCOG_00171 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GGJMDCOG_00172 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
GGJMDCOG_00173 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GGJMDCOG_00174 3.09e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00175 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00176 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00177 1.96e-49 - - - - - - - -
GGJMDCOG_00178 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GGJMDCOG_00179 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GGJMDCOG_00180 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
GGJMDCOG_00181 1.97e-227 pbpX2 - - V - - - Beta-lactamase
GGJMDCOG_00182 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GGJMDCOG_00183 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GGJMDCOG_00184 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GGJMDCOG_00185 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GGJMDCOG_00186 1.3e-26 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GGJMDCOG_00187 1.42e-58 - - - - - - - -
GGJMDCOG_00188 5.11e-265 - - - S - - - Membrane
GGJMDCOG_00189 3.41e-107 ykuL - - S - - - (CBS) domain
GGJMDCOG_00190 0.0 cadA - - P - - - P-type ATPase
GGJMDCOG_00191 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
GGJMDCOG_00192 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GGJMDCOG_00193 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
GGJMDCOG_00194 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GGJMDCOG_00195 1.91e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_00196 1.05e-67 - - - - - - - -
GGJMDCOG_00197 3.62e-202 - - - EGP - - - Major facilitator Superfamily
GGJMDCOG_00198 8.6e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GGJMDCOG_00199 3.43e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GGJMDCOG_00200 5.14e-248 - - - S - - - DUF218 domain
GGJMDCOG_00201 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00202 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGJMDCOG_00203 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
GGJMDCOG_00204 1.97e-255 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GGJMDCOG_00205 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GGJMDCOG_00206 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GGJMDCOG_00207 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GGJMDCOG_00208 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GGJMDCOG_00209 3.08e-205 - - - S - - - Aldo/keto reductase family
GGJMDCOG_00210 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GGJMDCOG_00211 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GGJMDCOG_00212 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GGJMDCOG_00213 6.64e-94 - - - - - - - -
GGJMDCOG_00214 2.56e-179 - - - S - - - haloacid dehalogenase-like hydrolase
GGJMDCOG_00215 9.69e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GGJMDCOG_00216 3.85e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GGJMDCOG_00217 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GGJMDCOG_00218 8.34e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00219 2.64e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GGJMDCOG_00220 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGJMDCOG_00221 7.82e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGJMDCOG_00222 7.1e-252 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GGJMDCOG_00223 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GGJMDCOG_00224 1.64e-45 - - - - - - - -
GGJMDCOG_00225 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
GGJMDCOG_00226 3.82e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GGJMDCOG_00227 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GGJMDCOG_00228 5.05e-11 - - - - - - - -
GGJMDCOG_00229 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GGJMDCOG_00230 2.18e-122 yneE - - K - - - Transcriptional regulator
GGJMDCOG_00231 1.92e-80 yneE - - K - - - Transcriptional regulator
GGJMDCOG_00232 9.01e-287 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_00233 7.18e-186 - - - S - - - haloacid dehalogenase-like hydrolase
GGJMDCOG_00234 1.28e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GGJMDCOG_00235 7.23e-50 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GGJMDCOG_00236 0.0 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_00237 2.27e-179 - - - - - - - -
GGJMDCOG_00241 2.23e-48 - - - - - - - -
GGJMDCOG_00242 2.52e-76 - - - S - - - Cupredoxin-like domain
GGJMDCOG_00243 4.44e-65 - - - S - - - Cupredoxin-like domain
GGJMDCOG_00244 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GGJMDCOG_00245 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
GGJMDCOG_00246 7.41e-136 - - - - - - - -
GGJMDCOG_00247 1.03e-65 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GGJMDCOG_00248 2.71e-222 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GGJMDCOG_00249 6.46e-27 - - - - - - - -
GGJMDCOG_00250 6.49e-268 - - - - - - - -
GGJMDCOG_00251 6.57e-175 - - - S - - - SLAP domain
GGJMDCOG_00252 1.14e-154 - - - S - - - SLAP domain
GGJMDCOG_00253 1.06e-133 - - - S - - - Bacteriocin helveticin-J
GGJMDCOG_00254 2.35e-58 - - - - - - - -
GGJMDCOG_00255 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_00256 1.98e-41 - - - E - - - Zn peptidase
GGJMDCOG_00257 0.0 eriC - - P ko:K03281 - ko00000 chloride
GGJMDCOG_00258 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGJMDCOG_00259 5.38e-39 - - - - - - - -
GGJMDCOG_00260 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GGJMDCOG_00261 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GGJMDCOG_00262 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGJMDCOG_00263 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GGJMDCOG_00264 2.65e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GGJMDCOG_00265 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GGJMDCOG_00266 4.47e-148 - - - L ko:K07497 - ko00000 hmm pf00665
GGJMDCOG_00267 7.7e-126 - - - L - - - Helix-turn-helix domain
GGJMDCOG_00268 0.0 - - - C - - - FMN_bind
GGJMDCOG_00269 3.53e-287 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GGJMDCOG_00270 2.52e-140 - - - K - - - LysR family
GGJMDCOG_00271 0.0 - - - C - - - FMN_bind
GGJMDCOG_00272 4.07e-140 - - - K - - - LysR family
GGJMDCOG_00273 1.18e-89 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_00274 2.28e-21 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_00275 1.22e-157 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GGJMDCOG_00276 4.92e-73 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
GGJMDCOG_00277 1.39e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
GGJMDCOG_00278 2.55e-223 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
GGJMDCOG_00279 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GGJMDCOG_00280 5.03e-297 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_00281 2.18e-103 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GGJMDCOG_00282 1.27e-311 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GGJMDCOG_00283 1.64e-59 yitW - - S - - - Iron-sulfur cluster assembly protein
GGJMDCOG_00284 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GGJMDCOG_00285 6.98e-78 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GGJMDCOG_00286 1.39e-224 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGJMDCOG_00287 6.22e-232 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GGJMDCOG_00288 4.43e-179 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GGJMDCOG_00289 2.09e-287 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_00290 3.53e-35 - - - C ko:K21832 - ko00000 nitric oxide dioxygenase activity
GGJMDCOG_00292 2.45e-64 - - - - - - - -
GGJMDCOG_00293 4.62e-101 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GGJMDCOG_00295 1.81e-22 repA - - S - - - Replication initiator protein A (RepA) N-terminus
GGJMDCOG_00296 6.72e-165 - - - - - - - -
GGJMDCOG_00297 5.13e-70 - - - - - - - -
GGJMDCOG_00299 8.21e-116 - - - D - - - ftsk spoiiie
GGJMDCOG_00300 5.48e-103 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_00301 4.55e-157 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGJMDCOG_00302 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_00303 1.01e-33 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGJMDCOG_00304 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
GGJMDCOG_00305 3.58e-135 - - - L - - - Transposase
GGJMDCOG_00306 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GGJMDCOG_00307 3.4e-93 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GGJMDCOG_00308 8.08e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GGJMDCOG_00309 1.17e-143 - - - - - - - -
GGJMDCOG_00311 7.04e-145 - - - E - - - Belongs to the SOS response-associated peptidase family
GGJMDCOG_00312 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GGJMDCOG_00313 1.5e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
GGJMDCOG_00314 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
GGJMDCOG_00315 1.71e-173 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GGJMDCOG_00316 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GGJMDCOG_00317 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGJMDCOG_00318 2.72e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GGJMDCOG_00319 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GGJMDCOG_00320 8.93e-194 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GGJMDCOG_00321 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
GGJMDCOG_00322 2.05e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GGJMDCOG_00323 1.81e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGJMDCOG_00324 5.52e-113 - - - - - - - -
GGJMDCOG_00325 0.0 - - - S - - - SLAP domain
GGJMDCOG_00326 5.4e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGJMDCOG_00327 1.37e-219 - - - GK - - - ROK family
GGJMDCOG_00328 1.03e-55 - - - - - - - -
GGJMDCOG_00329 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GGJMDCOG_00330 1.75e-89 - - - S - - - Domain of unknown function (DUF1934)
GGJMDCOG_00331 2.83e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GGJMDCOG_00332 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GGJMDCOG_00333 1.89e-312 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GGJMDCOG_00334 7.28e-97 - - - K - - - acetyltransferase
GGJMDCOG_00335 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GGJMDCOG_00336 2.07e-196 msmR - - K - - - AraC-like ligand binding domain
GGJMDCOG_00337 7.15e-295 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GGJMDCOG_00338 9.63e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GGJMDCOG_00339 1.1e-54 - - - K - - - Helix-turn-helix
GGJMDCOG_00340 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GGJMDCOG_00341 7.01e-207 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
GGJMDCOG_00342 3.06e-307 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
GGJMDCOG_00343 2.13e-53 - - - - - - - -
GGJMDCOG_00345 5.2e-119 - - - D - - - ftsk spoiiie
GGJMDCOG_00347 5.45e-72 - - - - - - - -
GGJMDCOG_00348 5.22e-18 - - - S - - - Domain of unknown function (DUF3173)
GGJMDCOG_00349 9.95e-214 - - - L - - - Belongs to the 'phage' integrase family
GGJMDCOG_00350 4e-79 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_00352 7.68e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GGJMDCOG_00353 3.64e-309 - - - M - - - Rib/alpha-like repeat
GGJMDCOG_00355 3.31e-65 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GGJMDCOG_00357 2.86e-169 - - - L - - - Transposase and inactivated derivatives
GGJMDCOG_00359 1.71e-154 - - - L ko:K07459 - ko00000 AAA ATPase domain
GGJMDCOG_00360 1.61e-145 - - - L - - - UvrD/REP helicase N-terminal domain
GGJMDCOG_00362 1.39e-143 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GGJMDCOG_00363 5.71e-230 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GGJMDCOG_00364 7.13e-67 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
GGJMDCOG_00365 1.53e-189 - 5.2.1.13 - Q ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
GGJMDCOG_00366 3.43e-79 - - - C - - - 2Fe-2S iron-sulfur cluster binding domain
GGJMDCOG_00368 4.97e-45 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
GGJMDCOG_00369 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
GGJMDCOG_00370 2.52e-06 - - - D - - - Domain of Unknown Function (DUF1542)
GGJMDCOG_00371 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GGJMDCOG_00372 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GGJMDCOG_00373 1.44e-164 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GGJMDCOG_00374 9e-104 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GGJMDCOG_00375 1.5e-93 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GGJMDCOG_00376 2.76e-112 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GGJMDCOG_00377 4.31e-175 - - - - - - - -
GGJMDCOG_00378 5.53e-147 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GGJMDCOG_00379 2.41e-39 - - - - - - - -
GGJMDCOG_00382 4.82e-144 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_00383 1.25e-94 - - - K - - - Helix-turn-helix domain
GGJMDCOG_00384 4.78e-261 - - - S - - - Domain of unknown function (DUF389)
GGJMDCOG_00385 1.53e-122 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_00386 6.49e-137 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_00387 2.23e-99 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
GGJMDCOG_00388 6.72e-177 - - - EP - - - Plasmid replication protein
GGJMDCOG_00389 4.63e-32 - - - - - - - -
GGJMDCOG_00390 7.71e-133 - - - L - - - Integrase
GGJMDCOG_00391 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GGJMDCOG_00392 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
GGJMDCOG_00393 3.07e-124 - - - - - - - -
GGJMDCOG_00394 0.0 - - - L - - - Transposase DDE domain
GGJMDCOG_00395 1.28e-168 - - - L - - - PFAM transposase IS116 IS110 IS902
GGJMDCOG_00396 1.08e-229 - - - L - - - DDE superfamily endonuclease
GGJMDCOG_00397 2.57e-206 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_00398 2.09e-105 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GGJMDCOG_00399 2.37e-169 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_00400 5.35e-170 - - - S - - - Uncharacterised protein family (UPF0236)
GGJMDCOG_00401 3.94e-183 - - - P - - - Voltage gated chloride channel
GGJMDCOG_00402 2.83e-237 - - - C - - - FMN-dependent dehydrogenase
GGJMDCOG_00403 1.05e-69 - - - - - - - -
GGJMDCOG_00404 1.17e-56 - - - - - - - -
GGJMDCOG_00405 1.33e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGJMDCOG_00406 0.0 - - - E - - - amino acid
GGJMDCOG_00407 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
GGJMDCOG_00408 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
GGJMDCOG_00409 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GGJMDCOG_00410 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GGJMDCOG_00411 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GGJMDCOG_00412 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GGJMDCOG_00413 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGJMDCOG_00414 7.52e-221 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_00415 1.23e-166 - - - S - - - (CBS) domain
GGJMDCOG_00416 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GGJMDCOG_00417 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GGJMDCOG_00418 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGJMDCOG_00419 6.06e-54 yabO - - J - - - S4 domain protein
GGJMDCOG_00420 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GGJMDCOG_00421 1.61e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
GGJMDCOG_00422 2.75e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GGJMDCOG_00423 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGJMDCOG_00424 3.91e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GGJMDCOG_00425 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGJMDCOG_00426 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GGJMDCOG_00427 2.84e-108 - - - K - - - FR47-like protein
GGJMDCOG_00432 4.19e-92 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GGJMDCOG_00433 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GGJMDCOG_00434 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GGJMDCOG_00435 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GGJMDCOG_00436 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GGJMDCOG_00437 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GGJMDCOG_00438 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GGJMDCOG_00439 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGJMDCOG_00440 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GGJMDCOG_00441 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GGJMDCOG_00442 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GGJMDCOG_00443 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GGJMDCOG_00444 3.3e-197 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GGJMDCOG_00445 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GGJMDCOG_00446 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGJMDCOG_00447 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGJMDCOG_00448 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GGJMDCOG_00449 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GGJMDCOG_00450 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GGJMDCOG_00451 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GGJMDCOG_00452 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GGJMDCOG_00453 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGJMDCOG_00454 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GGJMDCOG_00455 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GGJMDCOG_00456 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGJMDCOG_00457 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GGJMDCOG_00458 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GGJMDCOG_00459 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GGJMDCOG_00460 4.95e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GGJMDCOG_00461 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GGJMDCOG_00462 1.51e-154 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GGJMDCOG_00463 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGJMDCOG_00464 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GGJMDCOG_00465 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGJMDCOG_00466 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGJMDCOG_00467 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GGJMDCOG_00468 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GGJMDCOG_00469 5.91e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GGJMDCOG_00470 1.58e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GGJMDCOG_00471 1.53e-175 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GGJMDCOG_00472 5.08e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GGJMDCOG_00473 5.35e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GGJMDCOG_00474 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GGJMDCOG_00475 1.93e-138 - - - L - - - Phage integrase family
GGJMDCOG_00476 4.47e-81 - - - L - - - Phage integrase family
GGJMDCOG_00478 4.4e-86 - - - K - - - LytTr DNA-binding domain
GGJMDCOG_00479 6.11e-66 - - - S - - - Protein of unknown function (DUF3021)
GGJMDCOG_00480 2.64e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GGJMDCOG_00481 1.56e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GGJMDCOG_00482 1.49e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
GGJMDCOG_00483 1.56e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
GGJMDCOG_00484 1.46e-206 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GGJMDCOG_00485 2.42e-33 - - - - - - - -
GGJMDCOG_00486 8.07e-163 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGJMDCOG_00487 5.69e-235 - - - S - - - AAA domain
GGJMDCOG_00488 8.69e-66 - - - - - - - -
GGJMDCOG_00489 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GGJMDCOG_00490 1.11e-69 - - - - - - - -
GGJMDCOG_00491 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GGJMDCOG_00492 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GGJMDCOG_00493 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GGJMDCOG_00494 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GGJMDCOG_00495 2.45e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GGJMDCOG_00496 2.69e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGJMDCOG_00497 1.55e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GGJMDCOG_00498 1.19e-45 - - - - - - - -
GGJMDCOG_00499 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GGJMDCOG_00500 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GGJMDCOG_00501 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GGJMDCOG_00502 5e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GGJMDCOG_00503 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GGJMDCOG_00504 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GGJMDCOG_00505 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GGJMDCOG_00506 1.13e-210 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GGJMDCOG_00507 3.52e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GGJMDCOG_00508 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GGJMDCOG_00509 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GGJMDCOG_00510 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GGJMDCOG_00511 7.66e-116 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_00513 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGJMDCOG_00514 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GGJMDCOG_00515 9.32e-189 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
GGJMDCOG_00516 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GGJMDCOG_00517 6.15e-36 - - - - - - - -
GGJMDCOG_00518 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GGJMDCOG_00519 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GGJMDCOG_00520 1.12e-136 - - - M - - - family 8
GGJMDCOG_00521 1.15e-47 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
GGJMDCOG_00522 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GGJMDCOG_00523 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GGJMDCOG_00524 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
GGJMDCOG_00525 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGJMDCOG_00526 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
GGJMDCOG_00527 8.4e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GGJMDCOG_00528 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
GGJMDCOG_00529 3.05e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GGJMDCOG_00530 4.27e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GGJMDCOG_00531 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
GGJMDCOG_00532 3.69e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GGJMDCOG_00533 3.93e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GGJMDCOG_00534 1.94e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGJMDCOG_00535 1.28e-311 - - - L ko:K07484 - ko00000 Transposase IS66 family
GGJMDCOG_00536 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
GGJMDCOG_00537 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GGJMDCOG_00538 9.48e-31 - - - - - - - -
GGJMDCOG_00539 6.8e-52 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GGJMDCOG_00540 6.43e-230 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GGJMDCOG_00541 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GGJMDCOG_00542 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GGJMDCOG_00543 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GGJMDCOG_00545 6.66e-27 - - - S - - - CAAX protease self-immunity
GGJMDCOG_00546 2.67e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GGJMDCOG_00548 4.11e-124 potE - - E - - - thought to be involved in transport amino acids across the membrane
GGJMDCOG_00550 2.23e-189 - - - S - - - Putative ABC-transporter type IV
GGJMDCOG_00552 5.61e-38 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGJMDCOG_00553 8.41e-199 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GGJMDCOG_00554 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GGJMDCOG_00555 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GGJMDCOG_00556 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GGJMDCOG_00557 2.14e-231 - - - M - - - CHAP domain
GGJMDCOG_00558 2.79e-102 - - - - - - - -
GGJMDCOG_00559 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGJMDCOG_00560 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GGJMDCOG_00561 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGJMDCOG_00562 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGJMDCOG_00563 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GGJMDCOG_00564 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GGJMDCOG_00565 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GGJMDCOG_00566 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGJMDCOG_00567 6.15e-268 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGJMDCOG_00568 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GGJMDCOG_00569 1.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GGJMDCOG_00570 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GGJMDCOG_00571 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
GGJMDCOG_00572 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGJMDCOG_00573 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
GGJMDCOG_00574 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GGJMDCOG_00575 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GGJMDCOG_00576 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GGJMDCOG_00577 5.62e-95 yslB - - S - - - Protein of unknown function (DUF2507)
GGJMDCOG_00578 4.13e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GGJMDCOG_00579 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GGJMDCOG_00580 1.55e-29 - - - - - - - -
GGJMDCOG_00581 4.28e-187 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GGJMDCOG_00582 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GGJMDCOG_00583 3.09e-71 - - - - - - - -
GGJMDCOG_00584 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GGJMDCOG_00585 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GGJMDCOG_00586 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GGJMDCOG_00587 9.89e-74 - - - - - - - -
GGJMDCOG_00588 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GGJMDCOG_00589 4.25e-119 yutD - - S - - - Protein of unknown function (DUF1027)
GGJMDCOG_00590 6.38e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GGJMDCOG_00591 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
GGJMDCOG_00592 6.9e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GGJMDCOG_00593 1.76e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GGJMDCOG_00621 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
GGJMDCOG_00622 5.94e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GGJMDCOG_00623 8.97e-47 - - - - - - - -
GGJMDCOG_00624 1.96e-127 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GGJMDCOG_00625 6.24e-210 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_00626 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
GGJMDCOG_00627 3.68e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GGJMDCOG_00628 5.35e-224 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GGJMDCOG_00629 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GGJMDCOG_00630 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GGJMDCOG_00631 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GGJMDCOG_00632 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GGJMDCOG_00634 2.72e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GGJMDCOG_00635 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
GGJMDCOG_00636 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
GGJMDCOG_00637 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
GGJMDCOG_00638 2.07e-203 - - - K - - - Transcriptional regulator
GGJMDCOG_00639 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GGJMDCOG_00640 1.13e-308 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GGJMDCOG_00641 4.47e-58 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GGJMDCOG_00642 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GGJMDCOG_00643 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GGJMDCOG_00644 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
GGJMDCOG_00645 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GGJMDCOG_00646 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00647 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
GGJMDCOG_00648 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GGJMDCOG_00649 1.78e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GGJMDCOG_00650 3.36e-42 - - - - - - - -
GGJMDCOG_00651 9.05e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
GGJMDCOG_00652 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_00653 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GGJMDCOG_00654 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
GGJMDCOG_00655 1.23e-242 - - - S - - - TerB-C domain
GGJMDCOG_00659 4.26e-22 - - - L ko:K07467 - ko00000 Replication initiation factor
GGJMDCOG_00660 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGJMDCOG_00661 5.23e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GGJMDCOG_00662 1.48e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGJMDCOG_00663 1.07e-141 tnpR1 - - L - - - Resolvase, N terminal domain
GGJMDCOG_00664 6.91e-92 - - - L - - - IS1381, transposase OrfA
GGJMDCOG_00665 4.87e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GGJMDCOG_00666 1.17e-38 - - - - - - - -
GGJMDCOG_00667 4.65e-184 - - - D - - - AAA domain
GGJMDCOG_00668 5.88e-212 repA - - S - - - Replication initiator protein A
GGJMDCOG_00669 1.14e-164 - - - S - - - Fic/DOC family
GGJMDCOG_00670 1.79e-74 - - - L - - - Resolvase, N-terminal
GGJMDCOG_00671 4.18e-208 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_00672 1.86e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
GGJMDCOG_00673 5.53e-173 - - - S - - - TerB-C domain
GGJMDCOG_00674 2.14e-312 - - - P - - - P-loop Domain of unknown function (DUF2791)
GGJMDCOG_00675 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
GGJMDCOG_00676 7.82e-80 - - - - - - - -
GGJMDCOG_00677 1.92e-285 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GGJMDCOG_00678 6.58e-175 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GGJMDCOG_00680 3.31e-79 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GGJMDCOG_00681 5.48e-24 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GGJMDCOG_00682 2.28e-112 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GGJMDCOG_00683 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
GGJMDCOG_00685 1.04e-41 - - - - - - - -
GGJMDCOG_00686 1.32e-218 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
GGJMDCOG_00687 1.25e-17 - - - - - - - -
GGJMDCOG_00688 1.83e-22 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00689 6.31e-99 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00690 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00691 1.33e-130 - - - M - - - LysM domain protein
GGJMDCOG_00692 5.68e-211 - - - D - - - nuclear chromosome segregation
GGJMDCOG_00693 8.92e-136 - - - G - - - Phosphoglycerate mutase family
GGJMDCOG_00694 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
GGJMDCOG_00695 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
GGJMDCOG_00696 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GGJMDCOG_00698 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GGJMDCOG_00700 1.93e-266 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GGJMDCOG_00701 1.06e-230 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GGJMDCOG_00702 2.47e-153 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GGJMDCOG_00703 1.43e-186 - - - K - - - SIS domain
GGJMDCOG_00704 6.76e-309 slpX - - S - - - SLAP domain
GGJMDCOG_00705 6.39e-32 - - - S - - - transposase or invertase
GGJMDCOG_00706 5.91e-14 - - - - - - - -
GGJMDCOG_00707 1.87e-306 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
GGJMDCOG_00710 6.42e-302 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_00711 1.15e-54 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_00712 2.17e-232 - - - - - - - -
GGJMDCOG_00713 1.87e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
GGJMDCOG_00714 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
GGJMDCOG_00715 3.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GGJMDCOG_00716 1.03e-261 - - - M - - - Glycosyl transferases group 1
GGJMDCOG_00717 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GGJMDCOG_00718 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GGJMDCOG_00719 9.83e-261 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_00720 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GGJMDCOG_00721 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GGJMDCOG_00722 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GGJMDCOG_00723 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GGJMDCOG_00724 2.62e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GGJMDCOG_00726 2.26e-118 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GGJMDCOG_00727 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GGJMDCOG_00728 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GGJMDCOG_00729 6.25e-268 camS - - S - - - sex pheromone
GGJMDCOG_00730 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GGJMDCOG_00731 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GGJMDCOG_00732 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GGJMDCOG_00733 5.58e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GGJMDCOG_00734 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GGJMDCOG_00735 1.46e-75 - - - - - - - -
GGJMDCOG_00736 9.92e-187 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GGJMDCOG_00737 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GGJMDCOG_00738 1.01e-256 flp - - V - - - Beta-lactamase
GGJMDCOG_00739 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGJMDCOG_00740 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
GGJMDCOG_00745 0.0 qacA - - EGP - - - Major Facilitator
GGJMDCOG_00746 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GGJMDCOG_00747 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GGJMDCOG_00748 6.61e-186 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_00749 6.33e-221 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
GGJMDCOG_00750 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GGJMDCOG_00751 6.58e-293 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GGJMDCOG_00752 4.82e-42 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GGJMDCOG_00753 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
GGJMDCOG_00754 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
GGJMDCOG_00755 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GGJMDCOG_00756 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
GGJMDCOG_00757 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GGJMDCOG_00758 1.01e-22 - - - L - - - Transposase
GGJMDCOG_00759 7.51e-16 - - - L - - - Transposase
GGJMDCOG_00760 3.76e-18 - - - K - - - Acetyltransferase (GNAT) domain
GGJMDCOG_00761 1.71e-128 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGJMDCOG_00762 1.09e-148 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GGJMDCOG_00763 3.26e-292 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_00764 4.65e-120 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_00765 8.87e-226 ydbI - - K - - - AI-2E family transporter
GGJMDCOG_00766 3.93e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
GGJMDCOG_00767 2.55e-26 - - - - - - - -
GGJMDCOG_00768 1.59e-315 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GGJMDCOG_00769 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00770 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GGJMDCOG_00771 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GGJMDCOG_00772 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GGJMDCOG_00773 4.17e-201 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GGJMDCOG_00774 5.74e-206 yvgN - - C - - - Aldo keto reductase
GGJMDCOG_00775 0.0 fusA1 - - J - - - elongation factor G
GGJMDCOG_00776 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
GGJMDCOG_00777 1.07e-179 - - - EGP - - - Major Facilitator Superfamily
GGJMDCOG_00778 9.62e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGJMDCOG_00779 1.44e-07 - - - S - - - YSIRK type signal peptide
GGJMDCOG_00782 5.73e-201 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GGJMDCOG_00783 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GGJMDCOG_00784 0.0 - - - L - - - Helicase C-terminal domain protein
GGJMDCOG_00785 1.36e-260 pbpX - - V - - - Beta-lactamase
GGJMDCOG_00786 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GGJMDCOG_00787 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GGJMDCOG_00788 3.55e-28 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GGJMDCOG_00789 3.34e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GGJMDCOG_00790 4.14e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GGJMDCOG_00791 0.0 qacA - - EGP - - - Major Facilitator
GGJMDCOG_00792 1.06e-195 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
GGJMDCOG_00793 2.33e-230 pepA - - E - - - M42 glutamyl aminopeptidase
GGJMDCOG_00794 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
GGJMDCOG_00795 6.07e-223 ydhF - - S - - - Aldo keto reductase
GGJMDCOG_00796 1.53e-176 - - - - - - - -
GGJMDCOG_00797 1.11e-256 steT - - E ko:K03294 - ko00000 amino acid
GGJMDCOG_00798 3.97e-33 steT - - E ko:K03294 - ko00000 amino acid
GGJMDCOG_00799 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
GGJMDCOG_00800 1.07e-165 - - - F - - - glutamine amidotransferase
GGJMDCOG_00801 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GGJMDCOG_00802 7.27e-106 - - - K - - - Transcriptional regulator, MarR family
GGJMDCOG_00803 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00804 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
GGJMDCOG_00805 1.72e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GGJMDCOG_00806 8.41e-314 - - - G - - - MFS/sugar transport protein
GGJMDCOG_00807 5.43e-50 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GGJMDCOG_00808 2.72e-60 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GGJMDCOG_00809 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00810 3.39e-187 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_00811 4.29e-122 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00812 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00813 1.04e-211 - - - S - - - Protein of unknown function (DUF2974)
GGJMDCOG_00814 2.09e-110 - - - - - - - -
GGJMDCOG_00815 3.52e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GGJMDCOG_00816 2.2e-308 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_00817 7.29e-209 - - - C - - - Domain of unknown function (DUF4931)
GGJMDCOG_00818 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGJMDCOG_00819 1.82e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GGJMDCOG_00820 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GGJMDCOG_00821 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GGJMDCOG_00822 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
GGJMDCOG_00823 3.18e-198 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GGJMDCOG_00824 2.9e-79 - - - S - - - Enterocin A Immunity
GGJMDCOG_00825 4.44e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GGJMDCOG_00826 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GGJMDCOG_00827 1.85e-205 - - - S - - - Phospholipase, patatin family
GGJMDCOG_00828 7.44e-189 - - - S - - - hydrolase
GGJMDCOG_00829 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
GGJMDCOG_00830 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GGJMDCOG_00831 1.52e-103 - - - - - - - -
GGJMDCOG_00832 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GGJMDCOG_00833 1.76e-52 - - - - - - - -
GGJMDCOG_00834 2.14e-154 - - - C - - - nitroreductase
GGJMDCOG_00835 0.0 yhdP - - S - - - Transporter associated domain
GGJMDCOG_00836 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GGJMDCOG_00837 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GGJMDCOG_00838 2.88e-113 - - - L - - - PFAM transposase, IS4 family protein
GGJMDCOG_00839 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
GGJMDCOG_00840 6.74e-269 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GGJMDCOG_00841 7.32e-157 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GGJMDCOG_00842 2.22e-296 - - - E ko:K03294 - ko00000 amino acid
GGJMDCOG_00843 6.73e-78 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GGJMDCOG_00844 2.16e-79 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GGJMDCOG_00845 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
GGJMDCOG_00846 3.76e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GGJMDCOG_00848 1.62e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GGJMDCOG_00849 6.59e-296 - - - L - - - Transposase DDE domain
GGJMDCOG_00850 7.46e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
GGJMDCOG_00851 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GGJMDCOG_00852 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GGJMDCOG_00853 3.44e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GGJMDCOG_00854 3.22e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GGJMDCOG_00855 2.12e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GGJMDCOG_00856 4.42e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GGJMDCOG_00857 7.74e-61 - - - - - - - -
GGJMDCOG_00858 1.84e-44 ybcH - - D ko:K06889 - ko00000 Alpha beta
GGJMDCOG_00859 1.94e-150 ybcH - - D ko:K06889 - ko00000 Alpha beta
GGJMDCOG_00860 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGJMDCOG_00861 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GGJMDCOG_00862 1.74e-111 - - - - - - - -
GGJMDCOG_00863 7.76e-98 - - - - - - - -
GGJMDCOG_00864 1.76e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
GGJMDCOG_00865 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GGJMDCOG_00866 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GGJMDCOG_00867 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GGJMDCOG_00868 2.6e-37 - - - - - - - -
GGJMDCOG_00869 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GGJMDCOG_00870 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGJMDCOG_00871 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GGJMDCOG_00872 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GGJMDCOG_00873 2.63e-205 coiA - - S ko:K06198 - ko00000 Competence protein
GGJMDCOG_00874 5.74e-148 yjbH - - Q - - - Thioredoxin
GGJMDCOG_00875 2.44e-143 - - - S - - - CYTH
GGJMDCOG_00876 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GGJMDCOG_00877 1.57e-194 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GGJMDCOG_00878 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GGJMDCOG_00879 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GGJMDCOG_00880 3.77e-122 - - - S - - - SNARE associated Golgi protein
GGJMDCOG_00881 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GGJMDCOG_00882 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
GGJMDCOG_00883 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
GGJMDCOG_00884 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GGJMDCOG_00885 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
GGJMDCOG_00886 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GGJMDCOG_00887 1.47e-284 ymfF - - S - - - Peptidase M16 inactive domain protein
GGJMDCOG_00888 5.49e-301 ymfH - - S - - - Peptidase M16
GGJMDCOG_00889 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GGJMDCOG_00890 1.63e-154 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
GGJMDCOG_00891 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGJMDCOG_00892 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGJMDCOG_00893 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GGJMDCOG_00894 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GGJMDCOG_00895 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GGJMDCOG_00896 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GGJMDCOG_00897 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GGJMDCOG_00898 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGJMDCOG_00899 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GGJMDCOG_00900 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GGJMDCOG_00901 8.33e-27 - - - - - - - -
GGJMDCOG_00902 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GGJMDCOG_00903 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GGJMDCOG_00904 3.31e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GGJMDCOG_00905 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GGJMDCOG_00906 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GGJMDCOG_00907 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GGJMDCOG_00908 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GGJMDCOG_00909 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
GGJMDCOG_00910 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GGJMDCOG_00911 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GGJMDCOG_00912 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GGJMDCOG_00913 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GGJMDCOG_00914 0.0 - - - S - - - SH3-like domain
GGJMDCOG_00915 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_00916 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
GGJMDCOG_00917 4.64e-63 - - - S - - - Domain of unknown function (DUF4811)
GGJMDCOG_00918 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GGJMDCOG_00919 7.65e-101 - - - K - - - MerR HTH family regulatory protein
GGJMDCOG_00920 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
GGJMDCOG_00921 0.0 ycaM - - E - - - amino acid
GGJMDCOG_00922 0.0 - - - - - - - -
GGJMDCOG_00924 9.26e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
GGJMDCOG_00925 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GGJMDCOG_00926 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GGJMDCOG_00927 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GGJMDCOG_00928 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GGJMDCOG_00929 3.07e-124 - - - - - - - -
GGJMDCOG_00930 2.81e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
GGJMDCOG_00931 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGJMDCOG_00932 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GGJMDCOG_00933 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GGJMDCOG_00934 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GGJMDCOG_00935 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GGJMDCOG_00936 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GGJMDCOG_00937 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00938 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_00939 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GGJMDCOG_00940 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GGJMDCOG_00941 2.76e-221 ybbR - - S - - - YbbR-like protein
GGJMDCOG_00942 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGJMDCOG_00943 8.04e-190 - - - S - - - hydrolase
GGJMDCOG_00944 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
GGJMDCOG_00945 2.85e-153 - - - - - - - -
GGJMDCOG_00946 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGJMDCOG_00947 2.52e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GGJMDCOG_00948 8.39e-195 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GGJMDCOG_00949 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GGJMDCOG_00950 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GGJMDCOG_00951 5.12e-199 ybcH - - D ko:K06889 - ko00000 Alpha beta
GGJMDCOG_00952 6.91e-118 - - - T - - - Putative diguanylate phosphodiesterase
GGJMDCOG_00953 2.21e-34 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
GGJMDCOG_00954 1.67e-136 icaA - - M - - - Glycosyl transferase family group 2
GGJMDCOG_00955 2.64e-46 - - - - - - - -
GGJMDCOG_00956 1.96e-110 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
GGJMDCOG_00957 1.14e-99 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGJMDCOG_00959 0.0 - - - E - - - Amino acid permease
GGJMDCOG_00960 2.15e-127 - - - L - - - Helix-turn-helix domain
GGJMDCOG_00961 4.31e-204 - - - L ko:K07497 - ko00000 hmm pf00665
GGJMDCOG_00963 3.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GGJMDCOG_00964 1.49e-130 ylbE - - GM - - - NAD(P)H-binding
GGJMDCOG_00965 2.33e-120 - - - S - - - VanZ like family
GGJMDCOG_00966 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
GGJMDCOG_00967 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GGJMDCOG_00968 1.72e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GGJMDCOG_00969 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GGJMDCOG_00970 8.19e-91 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
GGJMDCOG_00971 1.68e-55 - - - - - - - -
GGJMDCOG_00972 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GGJMDCOG_00973 3.69e-30 - - - - - - - -
GGJMDCOG_00974 2.42e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GGJMDCOG_00975 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGJMDCOG_00977 3e-128 - - - M - - - Protein of unknown function (DUF3737)
GGJMDCOG_00978 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GGJMDCOG_00979 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GGJMDCOG_00980 9.01e-90 - - - S - - - SdpI/YhfL protein family
GGJMDCOG_00981 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
GGJMDCOG_00982 0.0 yclK - - T - - - Histidine kinase
GGJMDCOG_00983 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GGJMDCOG_00984 1.52e-136 vanZ - - V - - - VanZ like family
GGJMDCOG_00985 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GGJMDCOG_00986 4.63e-274 - - - EGP - - - Major Facilitator
GGJMDCOG_00987 3.94e-250 ampC - - V - - - Beta-lactamase
GGJMDCOG_00990 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
GGJMDCOG_00991 9.98e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GGJMDCOG_00992 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GGJMDCOG_00993 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GGJMDCOG_00994 1.36e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GGJMDCOG_00995 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGJMDCOG_00996 1.01e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GGJMDCOG_00997 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGJMDCOG_00998 2.57e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GGJMDCOG_00999 3.24e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGJMDCOG_01000 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGJMDCOG_01001 1.04e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGJMDCOG_01002 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGJMDCOG_01003 2.45e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GGJMDCOG_01004 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
GGJMDCOG_01005 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GGJMDCOG_01006 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GGJMDCOG_01007 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
GGJMDCOG_01008 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GGJMDCOG_01009 9.45e-104 uspA - - T - - - universal stress protein
GGJMDCOG_01010 1.35e-56 - - - - - - - -
GGJMDCOG_01011 1.47e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GGJMDCOG_01012 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
GGJMDCOG_01013 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GGJMDCOG_01014 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GGJMDCOG_01015 3.52e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GGJMDCOG_01016 3.48e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGJMDCOG_01017 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GGJMDCOG_01018 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GGJMDCOG_01019 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_01020 1.06e-86 - - - S - - - GtrA-like protein
GGJMDCOG_01021 4.08e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GGJMDCOG_01022 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
GGJMDCOG_01023 8.53e-59 - - - - - - - -
GGJMDCOG_01024 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_01025 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GGJMDCOG_01026 3.02e-166 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GGJMDCOG_01027 2.91e-67 - - - - - - - -
GGJMDCOG_01028 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GGJMDCOG_01029 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GGJMDCOG_01030 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
GGJMDCOG_01031 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
GGJMDCOG_01032 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GGJMDCOG_01033 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GGJMDCOG_01034 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
GGJMDCOG_01035 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
GGJMDCOG_01036 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
GGJMDCOG_01037 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GGJMDCOG_01038 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GGJMDCOG_01039 6.55e-72 ftsL - - D - - - Cell division protein FtsL
GGJMDCOG_01040 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GGJMDCOG_01041 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGJMDCOG_01042 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGJMDCOG_01043 3.88e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GGJMDCOG_01044 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GGJMDCOG_01045 3.3e-315 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GGJMDCOG_01046 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGJMDCOG_01047 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GGJMDCOG_01048 2.42e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
GGJMDCOG_01049 4.01e-192 ylmH - - S - - - S4 domain protein
GGJMDCOG_01050 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GGJMDCOG_01051 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GGJMDCOG_01052 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
GGJMDCOG_01053 5.18e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GGJMDCOG_01054 1.22e-55 - - - - - - - -
GGJMDCOG_01055 2.05e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GGJMDCOG_01056 1.62e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GGJMDCOG_01057 9.98e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GGJMDCOG_01058 4.47e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GGJMDCOG_01059 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
GGJMDCOG_01060 2.31e-148 - - - S - - - repeat protein
GGJMDCOG_01061 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GGJMDCOG_01062 0.0 - - - L - - - Nuclease-related domain
GGJMDCOG_01063 1.75e-211 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GGJMDCOG_01064 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GGJMDCOG_01065 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
GGJMDCOG_01066 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GGJMDCOG_01067 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GGJMDCOG_01068 3.91e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GGJMDCOG_01069 4.05e-70 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GGJMDCOG_01070 5.21e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GGJMDCOG_01071 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GGJMDCOG_01072 1.42e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GGJMDCOG_01073 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GGJMDCOG_01074 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GGJMDCOG_01075 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GGJMDCOG_01076 3.64e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GGJMDCOG_01077 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GGJMDCOG_01078 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GGJMDCOG_01079 2.21e-190 - - - - - - - -
GGJMDCOG_01080 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGJMDCOG_01081 2.49e-282 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GGJMDCOG_01082 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GGJMDCOG_01083 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GGJMDCOG_01084 2.58e-48 potE - - E - - - Amino Acid
GGJMDCOG_01085 1.27e-220 potE - - E - - - Amino Acid
GGJMDCOG_01086 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGJMDCOG_01087 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GGJMDCOG_01088 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GGJMDCOG_01089 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GGJMDCOG_01090 3.29e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GGJMDCOG_01091 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGJMDCOG_01092 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GGJMDCOG_01093 9.03e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GGJMDCOG_01094 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGJMDCOG_01095 4.2e-249 pbpX1 - - V - - - Beta-lactamase
GGJMDCOG_01096 0.0 - - - I - - - Protein of unknown function (DUF2974)
GGJMDCOG_01097 2.08e-95 yfhC - - C - - - nitroreductase
GGJMDCOG_01098 8.85e-94 - - - S - - - Domain of unknown function (DUF4767)
GGJMDCOG_01099 1.43e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GGJMDCOG_01100 1.23e-187 - - - S - - - Uncharacterised protein, DegV family COG1307
GGJMDCOG_01101 1.94e-130 - - - I - - - PAP2 superfamily
GGJMDCOG_01103 1.61e-48 - - - S - - - Cytochrome B5
GGJMDCOG_01104 1.87e-213 arbZ - - I - - - Phosphate acyltransferases
GGJMDCOG_01105 5.48e-235 - - - M - - - Glycosyl transferase family 8
GGJMDCOG_01106 1.91e-236 - - - M - - - Glycosyl transferase family 8
GGJMDCOG_01107 7.23e-201 arbx - - M - - - Glycosyl transferase family 8
GGJMDCOG_01108 4.19e-192 - - - I - - - Acyl-transferase
GGJMDCOG_01110 1.09e-46 - - - - - - - -
GGJMDCOG_01112 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GGJMDCOG_01113 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GGJMDCOG_01114 0.0 yycH - - S - - - YycH protein
GGJMDCOG_01115 7.44e-192 yycI - - S - - - YycH protein
GGJMDCOG_01116 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GGJMDCOG_01117 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GGJMDCOG_01118 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGJMDCOG_01119 1.21e-243 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GGJMDCOG_01121 1.73e-227 - - - S - - - Conserved hypothetical protein 698
GGJMDCOG_01122 1.63e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GGJMDCOG_01123 3.87e-15 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
GGJMDCOG_01124 2.33e-130 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
GGJMDCOG_01125 2.43e-95 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GGJMDCOG_01126 4.36e-93 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GGJMDCOG_01127 8.44e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GGJMDCOG_01128 6.95e-50 - - - L - - - Transposase and inactivated derivatives, IS30 family
GGJMDCOG_01129 1.16e-13 - - - L - - - Psort location Cytoplasmic, score
GGJMDCOG_01130 1.32e-114 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GGJMDCOG_01131 1.91e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GGJMDCOG_01132 4.39e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GGJMDCOG_01133 7.5e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GGJMDCOG_01134 3.68e-176 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGJMDCOG_01136 1.5e-176 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_01137 2.24e-71 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GGJMDCOG_01138 8.41e-42 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GGJMDCOG_01139 2.25e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GGJMDCOG_01140 5.29e-256 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGJMDCOG_01141 5.75e-152 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GGJMDCOG_01142 4.83e-107 ybbB - - S - - - Protein of unknown function (DUF1211)
GGJMDCOG_01143 1.53e-142 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GGJMDCOG_01144 6.21e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
GGJMDCOG_01145 1.63e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GGJMDCOG_01146 0.0 - - - L - - - Plasmid pRiA4b ORF-3-like protein
GGJMDCOG_01147 2.81e-76 - - - EGP - - - Major Facilitator
GGJMDCOG_01148 4.45e-156 rbtT - - P ko:K13021 - ko00000,ko02000 Major Facilitator Superfamily
GGJMDCOG_01149 5.25e-258 XK27_00915 - - C - - - Luciferase-like monooxygenase
GGJMDCOG_01150 4.6e-113 - - - K - - - GNAT family
GGJMDCOG_01151 1.46e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GGJMDCOG_01153 2.46e-48 - - - - - - - -
GGJMDCOG_01154 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
GGJMDCOG_01155 1.58e-10 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01156 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01157 4.17e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GGJMDCOG_01158 8.21e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGJMDCOG_01159 1.86e-117 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GGJMDCOG_01160 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GGJMDCOG_01161 5.41e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GGJMDCOG_01162 2.16e-205 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GGJMDCOG_01163 3.87e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGJMDCOG_01164 1.7e-117 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_01165 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GGJMDCOG_01166 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GGJMDCOG_01167 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GGJMDCOG_01168 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GGJMDCOG_01169 5.26e-171 - - - H - - - Aldolase/RraA
GGJMDCOG_01170 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GGJMDCOG_01171 5.95e-197 - - - I - - - Alpha/beta hydrolase family
GGJMDCOG_01172 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GGJMDCOG_01173 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GGJMDCOG_01174 1.79e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GGJMDCOG_01175 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GGJMDCOG_01176 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
GGJMDCOG_01177 9.9e-30 - - - - - - - -
GGJMDCOG_01178 2.58e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GGJMDCOG_01179 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01180 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GGJMDCOG_01181 8.1e-87 - - - S - - - Domain of unknown function DUF1828
GGJMDCOG_01182 7.91e-14 - - - - - - - -
GGJMDCOG_01183 2.41e-66 - - - - - - - -
GGJMDCOG_01184 1.05e-226 citR - - K - - - Putative sugar-binding domain
GGJMDCOG_01185 9.28e-317 - - - S - - - Putative threonine/serine exporter
GGJMDCOG_01187 5.26e-15 - - - - - - - -
GGJMDCOG_01188 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGJMDCOG_01189 4.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GGJMDCOG_01190 3.8e-80 - - - - - - - -
GGJMDCOG_01191 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGJMDCOG_01192 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GGJMDCOG_01193 7.1e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GGJMDCOG_01194 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GGJMDCOG_01195 5.51e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GGJMDCOG_01196 4.66e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGJMDCOG_01197 1.19e-43 - - - S - - - reductase
GGJMDCOG_01198 2.98e-50 - - - S - - - reductase
GGJMDCOG_01199 6.32e-41 - - - S - - - reductase
GGJMDCOG_01200 1.83e-190 yxeH - - S - - - hydrolase
GGJMDCOG_01201 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGJMDCOG_01202 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GGJMDCOG_01203 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
GGJMDCOG_01204 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GGJMDCOG_01205 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGJMDCOG_01206 0.0 oatA - - I - - - Acyltransferase
GGJMDCOG_01207 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GGJMDCOG_01208 1.18e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GGJMDCOG_01209 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
GGJMDCOG_01210 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GGJMDCOG_01211 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GGJMDCOG_01212 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
GGJMDCOG_01213 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GGJMDCOG_01214 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GGJMDCOG_01215 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GGJMDCOG_01216 4.41e-216 yitL - - S ko:K00243 - ko00000 S1 domain
GGJMDCOG_01217 5.77e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GGJMDCOG_01218 4.62e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GGJMDCOG_01219 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GGJMDCOG_01220 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GGJMDCOG_01221 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GGJMDCOG_01222 1.93e-32 - - - G - - - Peptidase_C39 like family
GGJMDCOG_01223 2.16e-207 - - - M - - - NlpC/P60 family
GGJMDCOG_01224 6.67e-115 - - - G - - - Peptidase_C39 like family
GGJMDCOG_01225 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GGJMDCOG_01226 1.19e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GGJMDCOG_01227 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01228 5.75e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_01230 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GGJMDCOG_01231 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GGJMDCOG_01232 1.13e-41 - - - M - - - Lysin motif
GGJMDCOG_01233 1.96e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GGJMDCOG_01234 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GGJMDCOG_01235 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GGJMDCOG_01236 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GGJMDCOG_01237 3.52e-293 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GGJMDCOG_01238 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGJMDCOG_01239 9.41e-285 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_01240 2.14e-104 - - - S - - - AAA domain
GGJMDCOG_01241 6.97e-53 - - - F - - - NUDIX domain
GGJMDCOG_01242 4.87e-187 - - - F - - - Phosphorylase superfamily
GGJMDCOG_01243 2.81e-189 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
GGJMDCOG_01244 2.25e-125 yagE - - E - - - Amino acid permease
GGJMDCOG_01245 1.11e-41 yagE - - E - - - Amino acid permease
GGJMDCOG_01246 2.75e-111 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
GGJMDCOG_01247 1.22e-129 - - - L - - - Belongs to the 'phage' integrase family
GGJMDCOG_01250 4.09e-61 - - - S - - - Short C-terminal domain
GGJMDCOG_01251 1.57e-87 - - - K - - - Peptidase S24-like
GGJMDCOG_01252 2.97e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_01259 2.38e-28 - - - L - - - Psort location Cytoplasmic, score
GGJMDCOG_01276 4.84e-221 terL - - S - - - overlaps another CDS with the same product name
GGJMDCOG_01278 6.21e-116 - - - S - - - Phage portal protein
GGJMDCOG_01279 2.11e-56 - - - S - - - Clp protease
GGJMDCOG_01280 1.68e-99 - - - S - - - Phage capsid family
GGJMDCOG_01283 3.91e-38 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GGJMDCOG_01288 1.32e-219 - - - D - - - domain protein
GGJMDCOG_01290 1.35e-204 - - - S - - - Phage minor structural protein
GGJMDCOG_01300 2.78e-131 - - - M - - - hydrolase, family 25
GGJMDCOG_01301 2.81e-203 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGJMDCOG_01302 5.13e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GGJMDCOG_01303 1.8e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GGJMDCOG_01304 8.63e-191 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
GGJMDCOG_01305 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
GGJMDCOG_01306 3.67e-88 - - - P - - - NhaP-type Na H and K H
GGJMDCOG_01307 7.2e-49 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GGJMDCOG_01308 2.4e-118 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GGJMDCOG_01309 1.06e-198 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GGJMDCOG_01310 1.73e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGJMDCOG_01311 1.23e-194 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GGJMDCOG_01312 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGJMDCOG_01313 1.42e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GGJMDCOG_01314 7.31e-181 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
GGJMDCOG_01315 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GGJMDCOG_01316 8.06e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GGJMDCOG_01317 3.83e-231 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GGJMDCOG_01318 1.19e-97 - - - C - - - Aldo keto reductase
GGJMDCOG_01319 6.38e-59 - - - S - - - aldo-keto reductase (NADP) activity
GGJMDCOG_01320 5.61e-124 - - - M - - - LysM domain protein
GGJMDCOG_01321 5.49e-197 - - - L - - - Phage integrase, N-terminal SAM-like domain
GGJMDCOG_01322 9.93e-72 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GGJMDCOG_01323 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GGJMDCOG_01324 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GGJMDCOG_01325 3.03e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GGJMDCOG_01326 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GGJMDCOG_01327 7.88e-121 - - - C - - - Pyridoxamine 5'-phosphate oxidase
GGJMDCOG_01328 0.0 - - - E - - - Amino acid permease
GGJMDCOG_01329 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GGJMDCOG_01330 4.97e-311 ynbB - - P - - - aluminum resistance
GGJMDCOG_01331 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GGJMDCOG_01332 3.6e-106 - - - C - - - Flavodoxin
GGJMDCOG_01333 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GGJMDCOG_01334 2.25e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GGJMDCOG_01335 5.94e-148 - - - I - - - Acid phosphatase homologues
GGJMDCOG_01336 4.87e-262 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GGJMDCOG_01337 1.12e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GGJMDCOG_01338 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GGJMDCOG_01339 1.59e-259 pbpX1 - - V - - - Beta-lactamase
GGJMDCOG_01340 3.1e-127 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GGJMDCOG_01341 7.89e-124 - - - S - - - ECF-type riboflavin transporter, S component
GGJMDCOG_01342 1.87e-290 - - - S - - - Putative peptidoglycan binding domain
GGJMDCOG_01343 5.74e-108 - - - K - - - Acetyltransferase (GNAT) domain
GGJMDCOG_01344 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GGJMDCOG_01345 6.84e-243 - - - L ko:K07478 - ko00000 AAA C-terminal domain
GGJMDCOG_01346 1.12e-85 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GGJMDCOG_01347 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GGJMDCOG_01348 4.21e-129 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GGJMDCOG_01349 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GGJMDCOG_01351 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_01352 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
GGJMDCOG_01353 5.93e-302 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
GGJMDCOG_01355 0.0 - - - S - - - SLAP domain
GGJMDCOG_01356 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
GGJMDCOG_01357 4.29e-275 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GGJMDCOG_01358 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GGJMDCOG_01359 1e-156 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GGJMDCOG_01360 4.43e-94 - - - L - - - Transposase and inactivated derivatives, IS30 family
GGJMDCOG_01361 5.34e-133 - - - L - - - Transposase and inactivated derivatives, IS30 family
GGJMDCOG_01362 1.04e-144 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GGJMDCOG_01363 1.3e-62 - - - L - - - DNA helicase
GGJMDCOG_01364 6.75e-101 - - - S - - - HIRAN
GGJMDCOG_01365 8.53e-45 - - - - - - - -
GGJMDCOG_01366 3.02e-232 - - - - - - - -
GGJMDCOG_01367 5.77e-127 - - - S - - - AAA domain
GGJMDCOG_01368 8.99e-100 - - - S ko:K07126 - ko00000 Sel1-like repeats.
GGJMDCOG_01369 5.56e-07 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_01370 3.15e-132 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
GGJMDCOG_01371 1.61e-70 - - - - - - - -
GGJMDCOG_01372 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GGJMDCOG_01373 3.16e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GGJMDCOG_01374 3.24e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GGJMDCOG_01375 4.13e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GGJMDCOG_01376 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GGJMDCOG_01377 0.0 FbpA - - K - - - Fibronectin-binding protein
GGJMDCOG_01378 2.06e-88 - - - - - - - -
GGJMDCOG_01379 3.31e-204 - - - S - - - EDD domain protein, DegV family
GGJMDCOG_01380 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GGJMDCOG_01381 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
GGJMDCOG_01382 1.5e-90 - - - - - - - -
GGJMDCOG_01383 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
GGJMDCOG_01384 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GGJMDCOG_01385 5.57e-22 - - - S - - - Protein of unknown function (DUF1275)
GGJMDCOG_01386 4.52e-114 - - - S - - - Protein of unknown function (DUF1275)
GGJMDCOG_01387 5.03e-76 - - - K - - - Helix-turn-helix domain
GGJMDCOG_01388 1.17e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGJMDCOG_01389 1.05e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GGJMDCOG_01390 1.11e-234 - - - K - - - Transcriptional regulator
GGJMDCOG_01391 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GGJMDCOG_01392 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GGJMDCOG_01393 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GGJMDCOG_01394 0.0 snf - - KL - - - domain protein
GGJMDCOG_01395 1.73e-48 - - - - - - - -
GGJMDCOG_01396 1.24e-08 - - - - - - - -
GGJMDCOG_01397 4.83e-136 pncA - - Q - - - Isochorismatase family
GGJMDCOG_01398 1.51e-159 - - - - - - - -
GGJMDCOG_01401 4.13e-83 - - - - - - - -
GGJMDCOG_01402 3.56e-47 - - - - - - - -
GGJMDCOG_01405 4.45e-42 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GGJMDCOG_01406 5.4e-36 - - - - - - - -
GGJMDCOG_01407 9.12e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_01408 9.91e-150 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GGJMDCOG_01409 9.67e-104 - - - - - - - -
GGJMDCOG_01410 1.93e-308 cpdA - - S - - - Calcineurin-like phosphoesterase
GGJMDCOG_01411 1.68e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GGJMDCOG_01412 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GGJMDCOG_01413 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
GGJMDCOG_01414 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GGJMDCOG_01415 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GGJMDCOG_01416 5.5e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGJMDCOG_01417 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GGJMDCOG_01418 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GGJMDCOG_01419 9.62e-116 ypmB - - S - - - Protein conserved in bacteria
GGJMDCOG_01420 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GGJMDCOG_01421 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GGJMDCOG_01422 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GGJMDCOG_01423 3.02e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GGJMDCOG_01424 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GGJMDCOG_01425 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GGJMDCOG_01426 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GGJMDCOG_01427 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GGJMDCOG_01428 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GGJMDCOG_01429 4.4e-215 - - - - - - - -
GGJMDCOG_01430 4.01e-184 - - - - - - - -
GGJMDCOG_01431 1.27e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GGJMDCOG_01432 3.49e-36 - - - - - - - -
GGJMDCOG_01433 3.85e-193 - - - - - - - -
GGJMDCOG_01434 2.54e-176 - - - - - - - -
GGJMDCOG_01435 1.65e-180 - - - - - - - -
GGJMDCOG_01436 1.33e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GGJMDCOG_01437 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
GGJMDCOG_01438 2.86e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GGJMDCOG_01439 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GGJMDCOG_01440 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GGJMDCOG_01441 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GGJMDCOG_01442 4.34e-166 - - - S - - - Peptidase family M23
GGJMDCOG_01443 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GGJMDCOG_01444 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GGJMDCOG_01445 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GGJMDCOG_01446 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GGJMDCOG_01447 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GGJMDCOG_01448 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGJMDCOG_01449 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGJMDCOG_01450 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GGJMDCOG_01451 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GGJMDCOG_01452 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GGJMDCOG_01453 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GGJMDCOG_01454 1.34e-22 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GGJMDCOG_01455 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
GGJMDCOG_01456 9.49e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GGJMDCOG_01457 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
GGJMDCOG_01458 7.23e-244 ysdE - - P - - - Citrate transporter
GGJMDCOG_01459 3.34e-92 - - - S - - - Iron-sulphur cluster biosynthesis
GGJMDCOG_01460 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GGJMDCOG_01461 9.69e-25 - - - - - - - -
GGJMDCOG_01462 2e-149 - - - S - - - Peptidase family M23
GGJMDCOG_01463 1.22e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGJMDCOG_01465 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGJMDCOG_01466 5.47e-151 - - - - - - - -
GGJMDCOG_01467 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GGJMDCOG_01468 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GGJMDCOG_01469 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GGJMDCOG_01470 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GGJMDCOG_01471 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
GGJMDCOG_01472 0.0 - - - L - - - PLD-like domain
GGJMDCOG_01473 5.97e-55 - - - S - - - SnoaL-like domain
GGJMDCOG_01474 6.13e-70 - - - K - - - sequence-specific DNA binding
GGJMDCOG_01475 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
GGJMDCOG_01476 5.51e-35 - - - - - - - -
GGJMDCOG_01477 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01478 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01479 8.93e-108 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_01480 5.73e-153 - - - - - - - -
GGJMDCOG_01481 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
GGJMDCOG_01482 1.13e-126 - - - - - - - -
GGJMDCOG_01483 6.93e-140 - - - K - - - LysR substrate binding domain
GGJMDCOG_01484 4.04e-29 - - - - - - - -
GGJMDCOG_01485 1.07e-287 - - - S - - - Sterol carrier protein domain
GGJMDCOG_01486 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GGJMDCOG_01487 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GGJMDCOG_01488 5.39e-84 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGJMDCOG_01489 2.06e-298 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GGJMDCOG_01490 3.03e-177 lysR5 - - K - - - LysR substrate binding domain
GGJMDCOG_01491 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
GGJMDCOG_01492 4.97e-64 - - - S - - - Metal binding domain of Ada
GGJMDCOG_01493 5.01e-55 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GGJMDCOG_01495 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GGJMDCOG_01496 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGJMDCOG_01497 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GGJMDCOG_01498 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GGJMDCOG_01499 9.71e-47 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GGJMDCOG_01500 5.3e-32 - - - - - - - -
GGJMDCOG_01501 4.51e-60 - - - M - - - Glycosyl hydrolases family 25
GGJMDCOG_01502 1.54e-112 - - - M - - - Glycosyl hydrolases family 25
GGJMDCOG_01503 1.76e-38 - - - - - - - -
GGJMDCOG_01504 6.31e-27 - - - - - - - -
GGJMDCOG_01507 2.12e-27 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GGJMDCOG_01508 1.28e-54 - - - - - - - -
GGJMDCOG_01514 8.2e-07 - - - - - - - -
GGJMDCOG_01516 3.71e-154 - - - S - - - Baseplate J-like protein
GGJMDCOG_01517 2.37e-43 - - - - - - - -
GGJMDCOG_01518 4.6e-63 - - - - - - - -
GGJMDCOG_01519 9e-128 - - - - - - - -
GGJMDCOG_01520 6.91e-61 - - - - - - - -
GGJMDCOG_01521 1.19e-68 - - - M - - - LysM domain
GGJMDCOG_01522 0.0 - - - L - - - Phage tail tape measure protein TP901
GGJMDCOG_01525 1.1e-72 - - - - - - - -
GGJMDCOG_01526 7.86e-194 - - - S - - - Protein of unknown function (DUF3383)
GGJMDCOG_01527 7.95e-69 - - - - - - - -
GGJMDCOG_01528 1.8e-59 - - - - - - - -
GGJMDCOG_01529 2.18e-96 - - - - - - - -
GGJMDCOG_01531 1.83e-181 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
GGJMDCOG_01532 5.09e-76 - - - - - - - -
GGJMDCOG_01533 2.77e-137 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GGJMDCOG_01534 1.14e-16 - - - S - - - Lysin motif
GGJMDCOG_01535 5.89e-127 - - - S - - - Phage Mu protein F like protein
GGJMDCOG_01536 2.28e-178 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GGJMDCOG_01537 1.1e-235 - - - S - - - Terminase-like family
GGJMDCOG_01538 1.22e-24 - - - S - - - Terminase-like family
GGJMDCOG_01539 3.14e-48 - - - L ko:K07474 - ko00000 Terminase small subunit
GGJMDCOG_01540 7.69e-16 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
GGJMDCOG_01541 1.12e-45 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
GGJMDCOG_01550 1.08e-10 - - - - - - - -
GGJMDCOG_01551 5.99e-52 - - - L - - - Endodeoxyribonuclease RusA
GGJMDCOG_01557 8.93e-64 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GGJMDCOG_01558 3.2e-41 - - - S - - - Conserved phage C-terminus (Phg_2220_C)
GGJMDCOG_01559 1.11e-70 - - - S - - - Protein of unknown function (DUF1071)
GGJMDCOG_01563 2.36e-08 - - - K - - - DNA-binding protein
GGJMDCOG_01569 5.23e-122 - - - S - - - AntA/AntB antirepressor
GGJMDCOG_01570 8.72e-07 - - - - - - - -
GGJMDCOG_01575 1.71e-102 - - - S - - - DNA binding
GGJMDCOG_01576 1.21e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
GGJMDCOG_01577 7e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
GGJMDCOG_01583 1.09e-226 - - - L - - - Belongs to the 'phage' integrase family
GGJMDCOG_01584 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GGJMDCOG_01585 6.87e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GGJMDCOG_01586 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GGJMDCOG_01587 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGJMDCOG_01588 9.98e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GGJMDCOG_01589 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GGJMDCOG_01590 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GGJMDCOG_01591 1.67e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GGJMDCOG_01592 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GGJMDCOG_01593 1.61e-64 ylxQ - - J - - - ribosomal protein
GGJMDCOG_01594 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GGJMDCOG_01595 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GGJMDCOG_01596 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GGJMDCOG_01597 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GGJMDCOG_01598 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GGJMDCOG_01599 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GGJMDCOG_01600 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GGJMDCOG_01601 6.38e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGJMDCOG_01602 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GGJMDCOG_01603 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GGJMDCOG_01604 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GGJMDCOG_01605 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GGJMDCOG_01606 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GGJMDCOG_01607 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GGJMDCOG_01608 8.61e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GGJMDCOG_01609 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GGJMDCOG_01610 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GGJMDCOG_01611 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GGJMDCOG_01612 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GGJMDCOG_01613 4.16e-51 ynzC - - S - - - UPF0291 protein
GGJMDCOG_01614 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGJMDCOG_01615 7.18e-187 - - - E - - - GDSL-like Lipase/Acylhydrolase family
GGJMDCOG_01616 1.15e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GGJMDCOG_01617 4.96e-270 - - - S - - - SLAP domain
GGJMDCOG_01618 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GGJMDCOG_01619 8.68e-171 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GGJMDCOG_01620 2.08e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GGJMDCOG_01621 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GGJMDCOG_01622 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGJMDCOG_01623 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GGJMDCOG_01624 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GGJMDCOG_01625 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GGJMDCOG_01626 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01627 2.1e-31 - - - - - - - -
GGJMDCOG_01628 1.69e-06 - - - - - - - -
GGJMDCOG_01629 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GGJMDCOG_01630 4.69e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GGJMDCOG_01631 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GGJMDCOG_01632 2.8e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GGJMDCOG_01633 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_01634 3.06e-181 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_01635 1.53e-218 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_01636 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GGJMDCOG_01637 7.02e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GGJMDCOG_01638 1.04e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GGJMDCOG_01639 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GGJMDCOG_01640 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGJMDCOG_01641 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GGJMDCOG_01642 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
GGJMDCOG_01643 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GGJMDCOG_01644 2.2e-41 - - - - - - - -
GGJMDCOG_01645 3.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GGJMDCOG_01646 4.33e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GGJMDCOG_01647 1.71e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GGJMDCOG_01648 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GGJMDCOG_01649 1.98e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GGJMDCOG_01650 1.06e-308 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGJMDCOG_01651 4.41e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GGJMDCOG_01652 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGJMDCOG_01653 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GGJMDCOG_01654 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GGJMDCOG_01655 2.19e-100 - - - S - - - ASCH
GGJMDCOG_01656 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GGJMDCOG_01657 7.22e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GGJMDCOG_01658 6.44e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GGJMDCOG_01659 1.53e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GGJMDCOG_01660 5.64e-248 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GGJMDCOG_01661 7.19e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GGJMDCOG_01662 2.78e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGJMDCOG_01663 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GGJMDCOG_01664 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGJMDCOG_01665 2.14e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GGJMDCOG_01666 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GGJMDCOG_01667 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GGJMDCOG_01668 6.12e-193 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGJMDCOG_01669 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GGJMDCOG_01671 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GGJMDCOG_01672 0.0 - - - S - - - Predicted membrane protein (DUF2207)
GGJMDCOG_01673 8.57e-202 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GGJMDCOG_01674 2.73e-268 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GGJMDCOG_01676 1.23e-227 lipA - - I - - - Carboxylesterase family
GGJMDCOG_01677 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GGJMDCOG_01678 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01679 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GGJMDCOG_01680 9.38e-189 supH - - S - - - haloacid dehalogenase-like hydrolase
GGJMDCOG_01681 4.3e-66 - - - - - - - -
GGJMDCOG_01682 8.51e-50 - - - - - - - -
GGJMDCOG_01683 2.48e-80 - - - S - - - Alpha beta hydrolase
GGJMDCOG_01684 1.02e-29 - - - S - - - Alpha beta hydrolase
GGJMDCOG_01685 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GGJMDCOG_01686 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GGJMDCOG_01687 8.74e-62 - - - - - - - -
GGJMDCOG_01688 6.79e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GGJMDCOG_01689 6.69e-115 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GGJMDCOG_01690 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GGJMDCOG_01691 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GGJMDCOG_01692 2.04e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GGJMDCOG_01693 9.05e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GGJMDCOG_01694 1.01e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GGJMDCOG_01695 6.2e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GGJMDCOG_01696 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GGJMDCOG_01697 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGJMDCOG_01698 4.37e-132 - - - GM - - - NmrA-like family
GGJMDCOG_01699 3.87e-20 - - - K - - - FCD
GGJMDCOG_01700 1.45e-34 - - - K - - - FCD
GGJMDCOG_01701 2.94e-74 eriC - - P ko:K03281 - ko00000 chloride
GGJMDCOG_01702 1.59e-66 eriC - - P ko:K03281 - ko00000 chloride
GGJMDCOG_01703 2.28e-76 eriC - - P ko:K03281 - ko00000 chloride
GGJMDCOG_01704 5.2e-137 - - - L - - - PFAM Integrase catalytic
GGJMDCOG_01706 4.14e-113 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GGJMDCOG_01707 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GGJMDCOG_01708 3.86e-109 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_01709 6.38e-154 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GGJMDCOG_01710 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GGJMDCOG_01711 1.03e-47 - - - - - - - -
GGJMDCOG_01712 1.63e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GGJMDCOG_01713 1.56e-198 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GGJMDCOG_01714 1.6e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
GGJMDCOG_01715 4.75e-239 - - - M - - - Glycosyl transferase
GGJMDCOG_01716 3.67e-225 - - - G - - - Glycosyl hydrolases family 8
GGJMDCOG_01717 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GGJMDCOG_01718 2.42e-204 - - - L - - - HNH nucleases
GGJMDCOG_01719 1.4e-191 yhaH - - S - - - Protein of unknown function (DUF805)
GGJMDCOG_01720 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01721 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GGJMDCOG_01722 4.04e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GGJMDCOG_01723 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
GGJMDCOG_01724 1.14e-164 terC - - P - - - Integral membrane protein TerC family
GGJMDCOG_01725 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
GGJMDCOG_01726 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GGJMDCOG_01727 5.17e-169 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GGJMDCOG_01728 4.78e-308 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GGJMDCOG_01729 4.71e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGJMDCOG_01730 0.0 potE - - E - - - Amino Acid
GGJMDCOG_01731 9.84e-63 - - - S - - - Fic/DOC family
GGJMDCOG_01733 0.0 - - - - - - - -
GGJMDCOG_01734 2.05e-110 - - - - - - - -
GGJMDCOG_01735 1.92e-113 yhaH - - S - - - Protein of unknown function (DUF805)
GGJMDCOG_01736 2.65e-89 - - - O - - - OsmC-like protein
GGJMDCOG_01737 5.3e-264 - - - EGP - - - Major Facilitator Superfamily
GGJMDCOG_01738 3e-290 sptS - - T - - - Histidine kinase
GGJMDCOG_01739 2.14e-85 dltr - - K - - - response regulator
GGJMDCOG_01740 4.52e-35 dltr - - K - - - response regulator
GGJMDCOG_01741 3.99e-127 - - - T - - - Region found in RelA / SpoT proteins
GGJMDCOG_01742 5.69e-179 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_01743 1.14e-208 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GGJMDCOG_01744 2.14e-48 - - - - - - - -
GGJMDCOG_01745 3.94e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GGJMDCOG_01746 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GGJMDCOG_01747 4.16e-280 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GGJMDCOG_01748 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
GGJMDCOG_01749 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GGJMDCOG_01750 1.48e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GGJMDCOG_01751 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GGJMDCOG_01752 2.51e-184 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GGJMDCOG_01753 2.84e-240 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GGJMDCOG_01754 4.05e-209 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
GGJMDCOG_01755 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GGJMDCOG_01756 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GGJMDCOG_01757 1.1e-110 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GGJMDCOG_01758 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GGJMDCOG_01759 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GGJMDCOG_01760 2.76e-83 - - - - - - - -
GGJMDCOG_01761 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GGJMDCOG_01762 1.06e-256 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GGJMDCOG_01763 0.0 - - - E - - - Amino acid permease
GGJMDCOG_01764 1.5e-64 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_01765 4.23e-46 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_01767 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_01768 1.28e-09 - - - S - - - PFAM HicB family
GGJMDCOG_01769 1.22e-202 - - - S - - - interspecies interaction between organisms
GGJMDCOG_01770 3e-271 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_01771 6.79e-45 - - - - - - - -
GGJMDCOG_01773 1.92e-42 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GGJMDCOG_01774 3.96e-19 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GGJMDCOG_01776 1.21e-204 - - - - - - - -
GGJMDCOG_01777 9.64e-219 - - - - - - - -
GGJMDCOG_01778 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GGJMDCOG_01779 2.05e-286 ynbB - - P - - - aluminum resistance
GGJMDCOG_01780 1.82e-214 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGJMDCOG_01781 4.95e-89 yqhL - - P - - - Rhodanese-like protein
GGJMDCOG_01782 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GGJMDCOG_01783 9.32e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
GGJMDCOG_01784 7.92e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGJMDCOG_01785 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GGJMDCOG_01786 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GGJMDCOG_01787 0.0 - - - S - - - membrane
GGJMDCOG_01788 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
GGJMDCOG_01789 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GGJMDCOG_01790 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GGJMDCOG_01791 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GGJMDCOG_01792 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GGJMDCOG_01793 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGJMDCOG_01794 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GGJMDCOG_01795 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
GGJMDCOG_01797 1.75e-120 - - - - - - - -
GGJMDCOG_01798 3.7e-164 - - - S - - - SLAP domain
GGJMDCOG_01799 7.65e-65 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GGJMDCOG_01800 2.87e-107 - - - S - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_01801 3.2e-176 - - - S - - - Protein of unknown function (DUF3100)
GGJMDCOG_01802 2.48e-313 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
GGJMDCOG_01803 6.53e-291 - - - Q - - - Imidazolonepropionase and related amidohydrolases
GGJMDCOG_01804 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GGJMDCOG_01805 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
GGJMDCOG_01806 0.0 sufI - - Q - - - Multicopper oxidase
GGJMDCOG_01807 1.8e-34 - - - - - - - -
GGJMDCOG_01808 2.24e-202 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GGJMDCOG_01809 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
GGJMDCOG_01810 7.84e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GGJMDCOG_01811 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GGJMDCOG_01812 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GGJMDCOG_01813 3.72e-202 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_01814 4.57e-163 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01815 1.68e-149 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
GGJMDCOG_01816 1.48e-138 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
GGJMDCOG_01818 3.71e-76 yodB - - K - - - Transcriptional regulator, HxlR family
GGJMDCOG_01819 1.37e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGJMDCOG_01820 1.32e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GGJMDCOG_01821 2.43e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GGJMDCOG_01822 3.23e-108 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GGJMDCOG_01823 2.95e-283 - - - S - - - SLAP domain
GGJMDCOG_01824 4.28e-125 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GGJMDCOG_01825 2.19e-18 - - - - - - - -
GGJMDCOG_01826 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GGJMDCOG_01827 3.52e-163 csrR - - K - - - response regulator
GGJMDCOG_01828 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GGJMDCOG_01829 8.01e-276 ylbM - - S - - - Belongs to the UPF0348 family
GGJMDCOG_01830 5.95e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GGJMDCOG_01831 9.22e-141 yqeK - - H - - - Hydrolase, HD family
GGJMDCOG_01832 1.77e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GGJMDCOG_01833 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GGJMDCOG_01834 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GGJMDCOG_01835 3.01e-255 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_01836 1.25e-192 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGJMDCOG_01837 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GGJMDCOG_01838 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GGJMDCOG_01839 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GGJMDCOG_01840 6.18e-123 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GGJMDCOG_01841 1.1e-128 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_01842 5.59e-98 - - - - - - - -
GGJMDCOG_01843 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGJMDCOG_01844 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GGJMDCOG_01845 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GGJMDCOG_01846 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGJMDCOG_01847 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGJMDCOG_01848 7.81e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GGJMDCOG_01849 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGJMDCOG_01850 1.98e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GGJMDCOG_01851 2.53e-139 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GGJMDCOG_01852 1.33e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GGJMDCOG_01853 2.43e-239 - - - S - - - Bacteriocin helveticin-J
GGJMDCOG_01854 0.0 - - - M - - - Peptidase family M1 domain
GGJMDCOG_01855 2.04e-226 - - - S - - - SLAP domain
GGJMDCOG_01856 4.65e-278 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GGJMDCOG_01857 2.59e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GGJMDCOG_01858 8.78e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GGJMDCOG_01859 1.35e-71 ytpP - - CO - - - Thioredoxin
GGJMDCOG_01861 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GGJMDCOG_01862 1.63e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GGJMDCOG_01863 3.67e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01864 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GGJMDCOG_01865 1.2e-41 - - - - - - - -
GGJMDCOG_01866 3.12e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GGJMDCOG_01867 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
GGJMDCOG_01868 0.0 - - - - - - - -
GGJMDCOG_01869 9.67e-33 - - - S - - - Domain of unknown function DUF1829
GGJMDCOG_01871 4.53e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
GGJMDCOG_01872 0.0 yhaN - - L - - - AAA domain
GGJMDCOG_01873 1.27e-290 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GGJMDCOG_01874 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
GGJMDCOG_01875 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GGJMDCOG_01876 1.21e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GGJMDCOG_01877 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GGJMDCOG_01878 7.62e-134 - - - G - - - Phosphoglycerate mutase family
GGJMDCOG_01879 5.46e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GGJMDCOG_01880 2.74e-06 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_01881 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GGJMDCOG_01882 4.77e-248 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GGJMDCOG_01883 1.28e-226 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_01884 1.86e-91 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_01885 2.29e-112 - - - - - - - -
GGJMDCOG_01886 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGJMDCOG_01887 1.24e-232 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GGJMDCOG_01888 5.07e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGJMDCOG_01889 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
GGJMDCOG_01890 2.62e-199 epsV - - S - - - glycosyl transferase family 2
GGJMDCOG_01891 5.29e-164 - - - S - - - Alpha/beta hydrolase family
GGJMDCOG_01892 1.63e-180 - - - L - - - An automated process has identified a potential problem with this gene model
GGJMDCOG_01893 2.32e-47 - - - - - - - -
GGJMDCOG_01894 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGJMDCOG_01895 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
GGJMDCOG_01896 1.11e-177 - - - - - - - -
GGJMDCOG_01897 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GGJMDCOG_01898 5.85e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GGJMDCOG_01899 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
GGJMDCOG_01900 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GGJMDCOG_01901 8.18e-163 - - - - - - - -
GGJMDCOG_01902 1.69e-258 yibE - - S - - - overlaps another CDS with the same product name
GGJMDCOG_01903 7.8e-167 yibF - - S - - - overlaps another CDS with the same product name
GGJMDCOG_01904 1.63e-200 - - - I - - - alpha/beta hydrolase fold
GGJMDCOG_01905 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GGJMDCOG_01906 8.82e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGJMDCOG_01907 1.62e-105 yveB - - I - - - PAP2 superfamily
GGJMDCOG_01908 1.08e-161 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_01909 1.48e-139 - - - EGP - - - Major Facilitator
GGJMDCOG_01910 9.16e-301 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GGJMDCOG_01911 7.84e-95 - - - EGP - - - Major Facilitator
GGJMDCOG_01912 2.58e-45 - - - - - - - -
GGJMDCOG_01914 3.3e-42 - - - - - - - -
GGJMDCOG_01915 1.62e-96 - - - M - - - LysM domain
GGJMDCOG_01916 2.32e-86 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GGJMDCOG_01917 7.02e-36 - - - - - - - -
GGJMDCOG_01918 1.32e-105 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_01919 8.08e-108 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_01920 6.03e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GGJMDCOG_01921 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GGJMDCOG_01922 5.6e-129 - - - M - - - ErfK YbiS YcfS YnhG
GGJMDCOG_01923 2.23e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGJMDCOG_01924 9.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GGJMDCOG_01926 1.59e-61 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GGJMDCOG_01927 3.54e-300 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GGJMDCOG_01928 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GGJMDCOG_01929 2.69e-156 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
GGJMDCOG_01930 6.07e-138 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GGJMDCOG_01931 4.66e-179 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GGJMDCOG_01932 8.63e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GGJMDCOG_01933 8.73e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GGJMDCOG_01934 9.14e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GGJMDCOG_01935 4.84e-42 - - - - - - - -
GGJMDCOG_01936 3.11e-256 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_01937 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GGJMDCOG_01938 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GGJMDCOG_01939 1.39e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GGJMDCOG_01940 6.75e-216 - - - K - - - LysR substrate binding domain
GGJMDCOG_01941 9.32e-109 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_01942 1.41e-51 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GGJMDCOG_01943 3.01e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GGJMDCOG_01944 1.03e-206 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GGJMDCOG_01945 1.38e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GGJMDCOG_01946 8.7e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GGJMDCOG_01947 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGJMDCOG_01948 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GGJMDCOG_01949 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GGJMDCOG_01950 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GGJMDCOG_01951 3.75e-168 - - - K - - - rpiR family
GGJMDCOG_01952 7.66e-248 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GGJMDCOG_01953 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GGJMDCOG_01954 1.32e-151 - - - S - - - Putative esterase
GGJMDCOG_01955 3.39e-154 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GGJMDCOG_01956 1.92e-102 - - - K - - - Helix-turn-helix domain, rpiR family
GGJMDCOG_01958 0.0 mdr - - EGP - - - Major Facilitator
GGJMDCOG_01959 7.29e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGJMDCOG_01962 5.31e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GGJMDCOG_01965 1.38e-165 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_01966 9.06e-184 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_01967 1.44e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_01968 4.98e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
GGJMDCOG_01969 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGJMDCOG_01970 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GGJMDCOG_01971 3.2e-143 - - - S - - - SNARE associated Golgi protein
GGJMDCOG_01972 1.77e-194 - - - I - - - alpha/beta hydrolase fold
GGJMDCOG_01973 6.76e-80 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GGJMDCOG_01974 4.06e-109 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GGJMDCOG_01975 1.19e-19 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_01976 1.41e-37 - - - S ko:K07133 - ko00000 cog cog1373
GGJMDCOG_01977 2.35e-117 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GGJMDCOG_01978 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GGJMDCOG_01979 3.24e-290 - - - L - - - COG3547 Transposase and inactivated derivatives
GGJMDCOG_01980 1.2e-220 - - - - - - - -
GGJMDCOG_01981 1.86e-31 - - - K - - - Acetyltransferase (GNAT) domain
GGJMDCOG_01983 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
GGJMDCOG_01984 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
GGJMDCOG_01985 1.89e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
GGJMDCOG_01986 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GGJMDCOG_01987 2.12e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GGJMDCOG_01988 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
GGJMDCOG_01989 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_01990 1.34e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
GGJMDCOG_01991 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
GGJMDCOG_01992 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GGJMDCOG_01993 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GGJMDCOG_01994 1.29e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
GGJMDCOG_01995 5.11e-203 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGJMDCOG_01996 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
GGJMDCOG_01997 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
GGJMDCOG_01998 7.8e-10 - - - S - - - Protein of unknown function (DUF3290)
GGJMDCOG_01999 3.16e-179 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GGJMDCOG_02000 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GGJMDCOG_02002 4.83e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GGJMDCOG_02003 3.77e-113 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GGJMDCOG_02004 1.24e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GGJMDCOG_02005 9.29e-111 usp5 - - T - - - universal stress protein
GGJMDCOG_02006 2.58e-203 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
GGJMDCOG_02007 6.8e-175 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GGJMDCOG_02008 1.02e-154 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_02009 1.83e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GGJMDCOG_02010 6.82e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GGJMDCOG_02011 5.18e-109 - - - - - - - -
GGJMDCOG_02012 0.0 - - - S - - - Calcineurin-like phosphoesterase
GGJMDCOG_02013 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GGJMDCOG_02014 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GGJMDCOG_02015 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GGJMDCOG_02016 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGJMDCOG_02017 3.41e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
GGJMDCOG_02018 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GGJMDCOG_02019 2.31e-277 yqjV - - EGP - - - Major Facilitator Superfamily
GGJMDCOG_02020 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GGJMDCOG_02021 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GGJMDCOG_02022 6.55e-97 - - - - - - - -
GGJMDCOG_02023 3.75e-48 - - - S - - - PFAM Archaeal ATPase
GGJMDCOG_02025 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GGJMDCOG_02026 3.61e-60 - - - - - - - -
GGJMDCOG_02027 2.77e-25 - - - - - - - -
GGJMDCOG_02028 1.21e-40 - - - - - - - -
GGJMDCOG_02029 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
GGJMDCOG_02030 2.95e-140 - - - S - - - SLAP domain
GGJMDCOG_02031 6.35e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_02033 4.56e-191 - - - S - - - PD-(D/E)XK nuclease family transposase
GGJMDCOG_02035 3.6e-101 - - - K - - - DNA-templated transcription, initiation
GGJMDCOG_02036 2.85e-54 - - - - - - - -
GGJMDCOG_02038 6.62e-161 - - - S - - - SLAP domain
GGJMDCOG_02040 2.09e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GGJMDCOG_02041 7.32e-232 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GGJMDCOG_02042 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GGJMDCOG_02043 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GGJMDCOG_02044 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GGJMDCOG_02045 1.98e-168 - - - - - - - -
GGJMDCOG_02046 1.72e-149 - - - - - - - -
GGJMDCOG_02047 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGJMDCOG_02048 5.18e-128 - - - G - - - Aldose 1-epimerase
GGJMDCOG_02049 2.92e-258 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GGJMDCOG_02050 1.03e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GGJMDCOG_02051 0.0 XK27_08315 - - M - - - Sulfatase
GGJMDCOG_02052 6.31e-84 - - - - - - - -
GGJMDCOG_02053 2.62e-69 - - - - - - - -
GGJMDCOG_02055 4.4e-165 - - - S - - - PAS domain
GGJMDCOG_02056 0.0 - - - V - - - ABC transporter transmembrane region
GGJMDCOG_02057 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GGJMDCOG_02058 1.75e-168 - - - T - - - Transcriptional regulatory protein, C terminal
GGJMDCOG_02059 2.37e-242 - - - T - - - GHKL domain
GGJMDCOG_02060 2.88e-98 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GGJMDCOG_02061 5.59e-109 - - - S - - - Peptidase propeptide and YPEB domain
GGJMDCOG_02062 8e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GGJMDCOG_02063 8.64e-85 yybA - - K - - - Transcriptional regulator
GGJMDCOG_02064 2.91e-83 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GGJMDCOG_02065 1.13e-201 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GGJMDCOG_02066 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GGJMDCOG_02067 1.73e-79 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GGJMDCOG_02068 1.45e-36 - - - S - - - Peptidase propeptide and YPEB domain
GGJMDCOG_02069 2.15e-299 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GGJMDCOG_02070 3.99e-56 - - - L - - - PFAM transposase IS116 IS110 IS902
GGJMDCOG_02071 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
GGJMDCOG_02072 1.48e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGJMDCOG_02073 1.95e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GGJMDCOG_02074 1.88e-125 - - - E - - - GDSL-like Lipase/Acylhydrolase
GGJMDCOG_02075 1.36e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
GGJMDCOG_02076 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GGJMDCOG_02077 9.78e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GGJMDCOG_02078 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GGJMDCOG_02079 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GGJMDCOG_02080 1.51e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GGJMDCOG_02081 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
GGJMDCOG_02082 1.87e-308 - - - S - - - response to antibiotic
GGJMDCOG_02083 1.34e-162 - - - - - - - -
GGJMDCOG_02084 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GGJMDCOG_02085 6.28e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GGJMDCOG_02086 1.42e-57 - - - - - - - -
GGJMDCOG_02087 4.65e-14 - - - - - - - -
GGJMDCOG_02088 7.81e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GGJMDCOG_02089 8.28e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GGJMDCOG_02090 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
GGJMDCOG_02091 8.75e-197 - - - - - - - -
GGJMDCOG_02092 3.32e-13 - - - - - - - -
GGJMDCOG_02093 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GGJMDCOG_02094 5.6e-135 - - - K ko:K06977 - ko00000 acetyltransferase
GGJMDCOG_02097 4.92e-20 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GGJMDCOG_02098 1.23e-58 - - - S - - - polysaccharide biosynthetic process
GGJMDCOG_02099 6.06e-41 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GGJMDCOG_02100 2.24e-29 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GGJMDCOG_02101 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GGJMDCOG_02102 1.93e-56 - - - L - - - Transposase DDE domain
GGJMDCOG_02104 4.63e-250 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GGJMDCOG_02107 1.25e-248 - - - K - - - IrrE N-terminal-like domain
GGJMDCOG_02108 3.95e-74 - - - - - - - -
GGJMDCOG_02109 6.84e-15 - - - V - - - Abi-like protein
GGJMDCOG_02110 0.0 - - - L - - - AAA domain
GGJMDCOG_02112 8.06e-08 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
GGJMDCOG_02114 9.92e-152 cps3J - - M - - - Domain of unknown function (DUF4422)
GGJMDCOG_02115 2.91e-140 epsE2 - - M - - - Bacterial sugar transferase
GGJMDCOG_02116 2.22e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GGJMDCOG_02117 5.61e-160 ywqD - - D - - - Capsular exopolysaccharide family
GGJMDCOG_02118 5.52e-187 epsB - - M - - - biosynthesis protein
GGJMDCOG_02119 8.14e-241 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GGJMDCOG_02121 6.72e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGJMDCOG_02122 1.26e-223 - - - S - - - Cysteine-rich secretory protein family
GGJMDCOG_02123 3.01e-54 - - - - - - - -
GGJMDCOG_02124 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GGJMDCOG_02125 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GGJMDCOG_02126 1.47e-114 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GGJMDCOG_02127 4.26e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
GGJMDCOG_02128 4.52e-56 - - - - - - - -
GGJMDCOG_02129 0.0 - - - S - - - O-antigen ligase like membrane protein
GGJMDCOG_02130 8.77e-144 - - - - - - - -
GGJMDCOG_02131 5.48e-283 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GGJMDCOG_02132 3.7e-40 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GGJMDCOG_02133 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGJMDCOG_02134 1.16e-101 - - - - - - - -
GGJMDCOG_02135 1.58e-143 - - - S - - - Peptidase_C39 like family
GGJMDCOG_02136 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
GGJMDCOG_02137 7.35e-174 - - - S - - - Putative threonine/serine exporter
GGJMDCOG_02138 0.0 - - - S - - - ABC transporter
GGJMDCOG_02139 2.52e-76 - - - - - - - -
GGJMDCOG_02140 8.69e-93 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GGJMDCOG_02141 5.49e-46 - - - - - - - -
GGJMDCOG_02142 7.2e-40 - - - - - - - -
GGJMDCOG_02143 2.33e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GGJMDCOG_02144 5.74e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GGJMDCOG_02145 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GGJMDCOG_02146 7.27e-42 - - - - - - - -
GGJMDCOG_02147 1.47e-91 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
GGJMDCOG_02150 4.61e-37 - - - S - - - Enterocin A Immunity

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)