ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEFKHMGJ_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEFKHMGJ_00002 4.16e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEFKHMGJ_00003 2.87e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NEFKHMGJ_00004 9.42e-258 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEFKHMGJ_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEFKHMGJ_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEFKHMGJ_00007 5.06e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEFKHMGJ_00008 2.12e-97 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NEFKHMGJ_00009 2.26e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NEFKHMGJ_00010 1.41e-130 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEFKHMGJ_00011 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEFKHMGJ_00012 5.33e-119 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NEFKHMGJ_00013 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
NEFKHMGJ_00014 3.26e-230 - - - C - - - Cytochrome bd terminal oxidase subunit II
NEFKHMGJ_00015 7.17e-39 - - - - - - - -
NEFKHMGJ_00016 4.58e-109 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_00017 1.25e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_00018 1.95e-107 - - - V ko:K01992 - ko00000,ko00002,ko02000 Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
NEFKHMGJ_00019 4.51e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00020 1.03e-244 - - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
NEFKHMGJ_00021 8.84e-266 - - - P - - - Pyridine nucleotide-disulphide oxidoreductase
NEFKHMGJ_00022 3.23e-204 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
NEFKHMGJ_00023 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00024 2.91e-164 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00025 7.36e-122 - - - K - - - transcriptional regulator
NEFKHMGJ_00026 3.58e-196 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
NEFKHMGJ_00027 1.58e-164 - - - S ko:K07090 - ko00000 membrane transporter protein
NEFKHMGJ_00028 1.71e-133 - - - S - - - Protein of unknown function (DUF1211)
NEFKHMGJ_00029 1.86e-146 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEFKHMGJ_00030 6.28e-73 - - - - - - - -
NEFKHMGJ_00031 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEFKHMGJ_00032 9.81e-142 - - - S - - - Membrane
NEFKHMGJ_00033 4.26e-109 - - - - - - - -
NEFKHMGJ_00034 3.11e-67 - - - - - - - -
NEFKHMGJ_00035 1.25e-66 - - - - - - - -
NEFKHMGJ_00036 1.95e-221 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NEFKHMGJ_00037 3.24e-158 azlC - - E - - - branched-chain amino acid
NEFKHMGJ_00038 1.29e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NEFKHMGJ_00039 0.0 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
NEFKHMGJ_00040 0.0 - - - M - - - Glycosyl hydrolase family 59
NEFKHMGJ_00041 5.06e-152 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NEFKHMGJ_00042 1.74e-226 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_00043 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NEFKHMGJ_00044 6.06e-278 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NEFKHMGJ_00045 0.0 uxuB 1.1.1.57 - G ko:K00040 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
NEFKHMGJ_00046 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
NEFKHMGJ_00047 2.4e-312 - - - G - - - Major Facilitator
NEFKHMGJ_00048 5.44e-163 kdgR - - K - - - FCD domain
NEFKHMGJ_00049 2.12e-243 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_00050 0.0 - - - M - - - Glycosyl hydrolase family 59
NEFKHMGJ_00051 2.31e-76 ps105 - - - - - - -
NEFKHMGJ_00052 3.77e-85 - - - S - - - pyridoxamine 5-phosphate
NEFKHMGJ_00053 1.05e-306 - - - EGP - - - Major Facilitator
NEFKHMGJ_00055 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEFKHMGJ_00056 4.54e-138 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NEFKHMGJ_00057 7.88e-157 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NEFKHMGJ_00058 7.18e-314 - 3.5.4.28, 3.5.4.31 - F ko:K12960 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
NEFKHMGJ_00059 6.44e-90 - - - S - - - An automated process has identified a potential problem with this gene model
NEFKHMGJ_00060 1.68e-191 - - - S - - - Protein of unknown function (DUF3100)
NEFKHMGJ_00062 1.37e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_00063 2.29e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEFKHMGJ_00064 2.13e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00065 3.03e-278 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00066 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NEFKHMGJ_00067 3.48e-44 copZ - - P - - - Heavy-metal-associated domain
NEFKHMGJ_00068 8.88e-132 dpsB - - P - - - Belongs to the Dps family
NEFKHMGJ_00069 1.75e-149 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
NEFKHMGJ_00070 2.39e-126 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_00071 4.84e-108 - - - S - - - Protein of unknown function with HXXEE motif
NEFKHMGJ_00073 7.21e-204 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_00075 1.4e-174 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEFKHMGJ_00076 3.93e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEFKHMGJ_00077 1.41e-136 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NEFKHMGJ_00078 1.72e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NEFKHMGJ_00079 2.3e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEFKHMGJ_00080 0.0 - - - EGP - - - Major Facilitator
NEFKHMGJ_00081 3.48e-142 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_00082 2.98e-153 - - - - - - - -
NEFKHMGJ_00084 1.93e-137 - 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 dTDP-4-dehydrorhamnose 3,5-epimerase
NEFKHMGJ_00085 2.58e-178 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEFKHMGJ_00086 3.2e-211 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEFKHMGJ_00087 2.39e-278 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEFKHMGJ_00088 4.19e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEFKHMGJ_00089 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEFKHMGJ_00091 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEFKHMGJ_00092 1.71e-239 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEFKHMGJ_00093 3.52e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEFKHMGJ_00094 1.52e-77 - - - - - - - -
NEFKHMGJ_00095 1.52e-94 - - - L - - - NUDIX domain
NEFKHMGJ_00096 1.55e-193 - - - EG - - - EamA-like transporter family
NEFKHMGJ_00098 3.17e-64 - - - L - - - PFAM transposase, IS4 family protein
NEFKHMGJ_00099 2.4e-137 - - - L - - - PFAM transposase, IS4 family protein
NEFKHMGJ_00100 5.57e-78 - - - K - - - Tetracyclin repressor, C-terminal all-alpha domain
NEFKHMGJ_00101 3.71e-68 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEFKHMGJ_00102 4.01e-99 - - - P - - - ABC-2 family transporter protein
NEFKHMGJ_00103 5.2e-125 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00104 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NEFKHMGJ_00105 4.7e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEFKHMGJ_00106 3.57e-314 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEFKHMGJ_00107 2.06e-280 - - - - - - - -
NEFKHMGJ_00108 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_00109 3.56e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEFKHMGJ_00110 5.42e-254 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NEFKHMGJ_00111 5.07e-202 yleF - - K - - - Helix-turn-helix domain, rpiR family
NEFKHMGJ_00112 9.89e-138 - - - K - - - Transcriptional regulator C-terminal region
NEFKHMGJ_00113 9.01e-164 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00114 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00115 2.94e-264 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
NEFKHMGJ_00116 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEFKHMGJ_00118 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NEFKHMGJ_00119 4.21e-72 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NEFKHMGJ_00120 2.7e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
NEFKHMGJ_00121 2.27e-36 - - - S - - - Phospholipase_D-nuclease N-terminal
NEFKHMGJ_00122 1.16e-155 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00123 2.66e-131 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEFKHMGJ_00124 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NEFKHMGJ_00125 6.59e-160 - - - - - - - -
NEFKHMGJ_00126 7.81e-33 - - - - - - - -
NEFKHMGJ_00129 6.56e-132 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NEFKHMGJ_00130 8.13e-238 yveB - - I - - - PAP2 superfamily
NEFKHMGJ_00131 3.07e-265 mccF - - V - - - LD-carboxypeptidase
NEFKHMGJ_00133 4.61e-57 - - - - - - - -
NEFKHMGJ_00134 1.15e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEFKHMGJ_00135 1.56e-55 - - - - - - - -
NEFKHMGJ_00136 7.43e-144 - - - - - - - -
NEFKHMGJ_00137 4.21e-289 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_00138 2.25e-111 - - - - - - - -
NEFKHMGJ_00139 2.8e-255 yclK - - T - - - Histidine kinase
NEFKHMGJ_00140 4.14e-155 - - - K - - - Transcriptional regulatory protein, C terminal
NEFKHMGJ_00141 3.5e-117 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NEFKHMGJ_00142 1.36e-244 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEFKHMGJ_00143 1.31e-54 - - - - - - - -
NEFKHMGJ_00144 7.9e-74 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NEFKHMGJ_00145 4.69e-70 - - - S - - - Protein of unknown function (DUF1516)
NEFKHMGJ_00146 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
NEFKHMGJ_00147 5.94e-71 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NEFKHMGJ_00149 3.99e-176 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_00150 6.05e-225 - - - P ko:K15551 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
NEFKHMGJ_00151 3.27e-183 - - - P ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_00152 0.0 - - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEFKHMGJ_00153 0.0 - - - S ko:K07112 - ko00000 Sulphur transport
NEFKHMGJ_00154 4.32e-144 - - - K - - - LysR substrate binding domain
NEFKHMGJ_00155 2.28e-188 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NEFKHMGJ_00156 6.33e-116 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NEFKHMGJ_00157 4.92e-243 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEFKHMGJ_00158 1.17e-57 - - - - - - - -
NEFKHMGJ_00159 9.29e-138 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEFKHMGJ_00160 0.0 - - - - - - - -
NEFKHMGJ_00162 4.74e-176 - - - S - - - WxL domain surface cell wall-binding
NEFKHMGJ_00163 2.83e-241 ynjC - - S - - - Cell surface protein
NEFKHMGJ_00164 0.0 - - - L - - - Mga helix-turn-helix domain
NEFKHMGJ_00165 1.86e-219 - - - S - - - Protein of unknown function (DUF805)
NEFKHMGJ_00166 8.37e-76 - - - - - - - -
NEFKHMGJ_00167 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEFKHMGJ_00168 4.17e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEFKHMGJ_00169 3.65e-171 - - - K - - - DeoR C terminal sensor domain
NEFKHMGJ_00170 0.0 - 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NEFKHMGJ_00171 9.14e-205 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00172 1.27e-308 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00173 3.89e-203 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEFKHMGJ_00174 1.39e-174 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NEFKHMGJ_00175 0.0 bmr3 - - EGP - - - Major Facilitator
NEFKHMGJ_00176 3.57e-28 - - - - - - - -
NEFKHMGJ_00178 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEFKHMGJ_00179 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEFKHMGJ_00180 8.11e-116 - - - - - - - -
NEFKHMGJ_00181 2.92e-144 - - - - - - - -
NEFKHMGJ_00182 2.37e-164 - - - - - - - -
NEFKHMGJ_00183 9.36e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_00184 7.37e-96 - - - - - - - -
NEFKHMGJ_00185 2.06e-103 - - - S - - - NUDIX domain
NEFKHMGJ_00186 2.66e-271 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
NEFKHMGJ_00187 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
NEFKHMGJ_00188 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NEFKHMGJ_00189 1.25e-149 - - - - - - - -
NEFKHMGJ_00190 3.49e-306 - - - S ko:K06872 - ko00000 TPM domain
NEFKHMGJ_00191 2.86e-183 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NEFKHMGJ_00192 1.85e-73 ywjH - - S - - - Protein of unknown function (DUF1634)
NEFKHMGJ_00193 1.47e-07 - - - - - - - -
NEFKHMGJ_00194 8.87e-85 - - - - - - - -
NEFKHMGJ_00195 2.59e-69 - - - - - - - -
NEFKHMGJ_00196 2.23e-107 - - - C - - - Flavodoxin
NEFKHMGJ_00197 4.57e-49 - - - - - - - -
NEFKHMGJ_00198 1.99e-36 - - - - - - - -
NEFKHMGJ_00199 1.22e-220 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEFKHMGJ_00200 1.87e-93 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
NEFKHMGJ_00201 1.55e-51 - - - S - - - Transglycosylase associated protein
NEFKHMGJ_00202 9.7e-116 - - - S - - - Protein conserved in bacteria
NEFKHMGJ_00203 1.32e-39 - - - - - - - -
NEFKHMGJ_00204 1.62e-80 asp23 - - S - - - Asp23 family, cell envelope-related function
NEFKHMGJ_00205 3.02e-87 asp2 - - S - - - Asp23 family, cell envelope-related function
NEFKHMGJ_00206 2.16e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEFKHMGJ_00207 4.96e-148 - - - S - - - Protein of unknown function (DUF969)
NEFKHMGJ_00208 5.63e-186 - - - S - - - Protein of unknown function (DUF979)
NEFKHMGJ_00209 6.93e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEFKHMGJ_00210 4.85e-136 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEFKHMGJ_00212 3.57e-165 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NEFKHMGJ_00213 2.32e-86 - - - - - - - -
NEFKHMGJ_00214 2.13e-171 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NEFKHMGJ_00215 5.2e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEFKHMGJ_00216 3.67e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NEFKHMGJ_00217 6.39e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEFKHMGJ_00218 8.4e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NEFKHMGJ_00219 8.02e-236 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEFKHMGJ_00220 3.39e-182 - - - S - - - Protein of unknown function (DUF1129)
NEFKHMGJ_00221 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEFKHMGJ_00222 1.22e-154 - - - - - - - -
NEFKHMGJ_00223 1.68e-156 vanR - - K - - - response regulator
NEFKHMGJ_00224 1.19e-279 hpk31 - - T - - - Histidine kinase
NEFKHMGJ_00225 5.54e-303 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEFKHMGJ_00227 5.76e-108 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEFKHMGJ_00228 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEFKHMGJ_00229 3.16e-181 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NEFKHMGJ_00230 2.26e-208 yvgN - - C - - - Aldo keto reductase
NEFKHMGJ_00231 1.96e-182 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_00232 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEFKHMGJ_00233 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NEFKHMGJ_00234 5.96e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NEFKHMGJ_00235 1.88e-226 iolC 2.7.1.92 - H ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NEFKHMGJ_00236 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NEFKHMGJ_00237 1.12e-245 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NEFKHMGJ_00238 1.01e-250 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NEFKHMGJ_00239 6.04e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NEFKHMGJ_00240 8.12e-204 iolJ 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00241 1.75e-87 yodA - - S - - - Tautomerase enzyme
NEFKHMGJ_00242 2.07e-204 - 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NEFKHMGJ_00243 2.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NEFKHMGJ_00244 3.12e-187 gntR - - K - - - rpiR family
NEFKHMGJ_00245 2.45e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NEFKHMGJ_00246 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NEFKHMGJ_00247 2.29e-270 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NEFKHMGJ_00248 1.85e-75 - - - - - - - -
NEFKHMGJ_00249 8.68e-169 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEFKHMGJ_00250 2.96e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEFKHMGJ_00251 3.1e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEFKHMGJ_00252 4.74e-206 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NEFKHMGJ_00253 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NEFKHMGJ_00254 6.87e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEFKHMGJ_00255 7.52e-315 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEFKHMGJ_00256 3.02e-99 - - - T - - - Sh3 type 3 domain protein
NEFKHMGJ_00257 2.29e-175 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_00258 1.34e-187 - - - M - - - Glycosyltransferase like family 2
NEFKHMGJ_00259 9.02e-172 - - - S - - - Protein of unknown function (DUF975)
NEFKHMGJ_00260 9.9e-69 - - - - - - - -
NEFKHMGJ_00261 1.45e-136 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEFKHMGJ_00262 2.19e-219 - 3.2.2.24 - O ko:K05521 - ko00000,ko01000 ADP-ribosylglycohydrolase
NEFKHMGJ_00263 0.0 - - - S - - - ABC transporter
NEFKHMGJ_00264 9.75e-175 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 - J ko:K02169,ko:K02528,ko:K17216,ko:K17462 ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 rRNA (adenine-N6,N6-)-dimethyltransferase activity
NEFKHMGJ_00265 1.45e-46 - - - - - - - -
NEFKHMGJ_00266 4.61e-93 - - - S - - - COG NOG38524 non supervised orthologous group
NEFKHMGJ_00268 1.46e-57 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEFKHMGJ_00269 1.14e-169 - - - S - - - Putative threonine/serine exporter
NEFKHMGJ_00270 1.7e-96 - - - S - - - Threonine/Serine exporter, ThrE
NEFKHMGJ_00271 4.62e-273 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NEFKHMGJ_00272 6.02e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEFKHMGJ_00273 8.13e-185 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEFKHMGJ_00274 5.83e-178 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NEFKHMGJ_00275 2.36e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_00276 4.89e-70 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
NEFKHMGJ_00277 5.34e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEFKHMGJ_00278 1.94e-304 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEFKHMGJ_00279 7.73e-146 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEFKHMGJ_00280 1.13e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEFKHMGJ_00281 1.23e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NEFKHMGJ_00282 1.09e-217 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NEFKHMGJ_00283 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NEFKHMGJ_00284 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NEFKHMGJ_00285 5.96e-185 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEFKHMGJ_00286 3.11e-75 lacF-1 2.7.1.207 - G ko:K02786 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEFKHMGJ_00287 2.1e-295 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEFKHMGJ_00288 5.09e-203 - - - - - - - -
NEFKHMGJ_00289 9.33e-153 - - - - - - - -
NEFKHMGJ_00290 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NEFKHMGJ_00291 1.94e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEFKHMGJ_00292 4.97e-111 - - - - - - - -
NEFKHMGJ_00293 1.66e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NEFKHMGJ_00294 1.33e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
NEFKHMGJ_00295 1.15e-280 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
NEFKHMGJ_00296 5.31e-287 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEFKHMGJ_00297 6.85e-154 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
NEFKHMGJ_00298 5.49e-284 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
NEFKHMGJ_00299 3.25e-107 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_00300 2.07e-179 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_00301 1.23e-185 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NEFKHMGJ_00302 3.18e-84 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEFKHMGJ_00303 7.95e-222 lacC 2.7.1.144 - F ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_00304 9.78e-189 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 KR domain
NEFKHMGJ_00305 1.74e-308 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00306 4.02e-111 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00307 8.14e-63 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00308 2.63e-207 - - - - - - - -
NEFKHMGJ_00309 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEFKHMGJ_00310 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NEFKHMGJ_00311 2.4e-279 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NEFKHMGJ_00312 7.98e-295 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEFKHMGJ_00313 8.52e-253 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEFKHMGJ_00314 0.0 - - - U ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEFKHMGJ_00315 2.02e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00316 1.31e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEFKHMGJ_00317 5.33e-244 - - - E - - - M42 glutamyl aminopeptidase
NEFKHMGJ_00318 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00319 2.34e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEFKHMGJ_00320 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEFKHMGJ_00321 9.5e-156 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
NEFKHMGJ_00323 2.23e-155 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
NEFKHMGJ_00324 5.22e-214 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
NEFKHMGJ_00325 1.86e-122 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NEFKHMGJ_00326 1.1e-310 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEFKHMGJ_00327 3.26e-143 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEFKHMGJ_00328 3.83e-163 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NEFKHMGJ_00329 8.48e-106 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
NEFKHMGJ_00330 2.69e-192 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEFKHMGJ_00331 3.38e-133 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEFKHMGJ_00332 7.09e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEFKHMGJ_00333 0.0 - - - E - - - Amino acid permease
NEFKHMGJ_00334 4.71e-239 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NEFKHMGJ_00335 2.78e-80 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEFKHMGJ_00336 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEFKHMGJ_00337 2.36e-205 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEFKHMGJ_00338 7.61e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
NEFKHMGJ_00339 4.69e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEFKHMGJ_00340 4.01e-52 - - - K - - - DNA-binding helix-turn-helix protein
NEFKHMGJ_00341 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
NEFKHMGJ_00342 7.78e-69 - - - - - - - -
NEFKHMGJ_00343 8.43e-112 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEFKHMGJ_00344 2.78e-99 - - - - - - - -
NEFKHMGJ_00345 5.1e-77 - - - - - - - -
NEFKHMGJ_00346 2.02e-116 - - - - - - - -
NEFKHMGJ_00347 1.79e-303 - - - EGP - - - Major Facilitator
NEFKHMGJ_00348 5.81e-91 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEFKHMGJ_00349 2.9e-134 - - - - - - - -
NEFKHMGJ_00350 8.52e-41 - - - - - - - -
NEFKHMGJ_00351 3.75e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
NEFKHMGJ_00352 1.34e-205 - - - GKT - - - transcriptional antiterminator
NEFKHMGJ_00353 1.27e-61 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00354 4.22e-287 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00355 9.66e-63 - - - - - - - -
NEFKHMGJ_00356 2.67e-191 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00357 7.76e-113 - - - S - - - Zeta toxin
NEFKHMGJ_00358 1.32e-199 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NEFKHMGJ_00359 9.09e-270 dcuC - - C ko:K03326 - ko00000,ko02000 Tripartite ATP-independent periplasmic transporter, DctM component
NEFKHMGJ_00361 2.13e-152 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEFKHMGJ_00362 7.94e-112 - - - G - - - DeoC/LacD family aldolase
NEFKHMGJ_00363 2.51e-48 - - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NEFKHMGJ_00364 5.7e-223 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NEFKHMGJ_00365 2.78e-117 fabG10 1.1.1.100, 1.3.1.28 - IQ ko:K00059,ko:K00216 ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
NEFKHMGJ_00366 9e-160 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEFKHMGJ_00367 1.77e-198 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00368 0.0 - - - K - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00369 2.62e-198 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00370 0.0 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_00371 4.9e-303 - - - E ko:K19956 ko00051,map00051 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NEFKHMGJ_00372 2.81e-209 - - - K - - - sugar-binding domain protein
NEFKHMGJ_00373 1.39e-167 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NEFKHMGJ_00374 2.14e-81 - 2.7.1.206 - G ko:K02812 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEFKHMGJ_00375 2.85e-103 - 2.7.1.206 - G ko:K02813 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_00376 6.96e-178 - - - U ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_00377 5.62e-191 manZ - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NEFKHMGJ_00378 1.12e-189 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00379 2.63e-203 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
NEFKHMGJ_00380 2.03e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NEFKHMGJ_00381 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding cassette cobalt transporter
NEFKHMGJ_00382 6.13e-190 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEFKHMGJ_00383 8.63e-192 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NEFKHMGJ_00384 4.15e-312 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NEFKHMGJ_00385 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEFKHMGJ_00386 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
NEFKHMGJ_00387 4.63e-124 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
NEFKHMGJ_00389 2.02e-236 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 iic component
NEFKHMGJ_00390 1.47e-08 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00391 4.95e-39 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00392 1.62e-81 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_00393 3.37e-67 - 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEFKHMGJ_00394 3.97e-73 gntR - - K - - - rpiR family
NEFKHMGJ_00395 8e-41 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00396 3.85e-230 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00397 4.79e-35 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NEFKHMGJ_00398 1.54e-166 - - - S - - - N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NEFKHMGJ_00399 1.66e-84 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEFKHMGJ_00400 4.21e-277 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
NEFKHMGJ_00401 5.83e-262 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEFKHMGJ_00402 1.28e-46 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NEFKHMGJ_00404 2.67e-11 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEFKHMGJ_00405 1.17e-55 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEFKHMGJ_00406 1.63e-66 - - - S - - - Haloacid dehalogenase-like hydrolase
NEFKHMGJ_00407 1.74e-288 - - - K ko:K02538 - ko00000,ko03000 PRD domain
NEFKHMGJ_00408 1.08e-35 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NEFKHMGJ_00409 2.95e-213 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEFKHMGJ_00410 2.9e-79 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00411 1.21e-60 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00412 1.38e-210 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
NEFKHMGJ_00413 1.18e-160 - - - G - - - Domain of unknown function (DUF4432)
NEFKHMGJ_00414 4.19e-143 - 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Pfam:DUF1498
NEFKHMGJ_00415 1.3e-244 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NEFKHMGJ_00416 4.85e-80 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00417 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00418 3.24e-241 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NEFKHMGJ_00419 2.63e-272 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00420 8.9e-83 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 SIS domain
NEFKHMGJ_00421 1.53e-56 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00422 3.78e-42 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_00423 1.23e-233 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_00424 8.31e-110 - 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
NEFKHMGJ_00425 2.4e-92 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NEFKHMGJ_00426 3.15e-241 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_00427 1.74e-15 - - - K - - - HxlR-like helix-turn-helix
NEFKHMGJ_00428 5.26e-73 - - - C - - - nitroreductase
NEFKHMGJ_00429 6.02e-163 - - - - - - - -
NEFKHMGJ_00431 4.39e-25 - - - S - - - YvrJ protein family
NEFKHMGJ_00432 1.2e-187 - - - M - - - hydrolase, family 25
NEFKHMGJ_00433 5.12e-112 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_00434 1.82e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00435 8.62e-155 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00436 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEFKHMGJ_00437 1.02e-191 - - - S - - - hydrolase
NEFKHMGJ_00438 4.77e-60 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
NEFKHMGJ_00439 3.26e-176 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NEFKHMGJ_00443 2.24e-98 - - - L - - - Resolvase, N-terminal
NEFKHMGJ_00444 2.48e-266 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEFKHMGJ_00446 1.17e-189 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEFKHMGJ_00447 5.37e-249 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NEFKHMGJ_00448 5.83e-224 - - - - - - - -
NEFKHMGJ_00449 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NEFKHMGJ_00450 1.61e-24 - - - - - - - -
NEFKHMGJ_00451 7.64e-131 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_00452 1.22e-77 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NEFKHMGJ_00453 5.78e-133 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NEFKHMGJ_00454 5.73e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NEFKHMGJ_00455 2.49e-100 - - - O - - - OsmC-like protein
NEFKHMGJ_00457 0.0 - - - L - - - Exonuclease
NEFKHMGJ_00458 5.54e-07 - - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
NEFKHMGJ_00459 1.38e-41 - - - L - - - RelB antitoxin
NEFKHMGJ_00460 1.04e-64 yczG - - K - - - Helix-turn-helix domain
NEFKHMGJ_00461 3.3e-261 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NEFKHMGJ_00462 8.46e-177 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_00463 5.78e-156 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEFKHMGJ_00464 4.15e-77 ydfF - - K - - - Transcriptional
NEFKHMGJ_00465 5.79e-132 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEFKHMGJ_00466 8.09e-44 - - - - - - - -
NEFKHMGJ_00467 7.61e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NEFKHMGJ_00468 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEFKHMGJ_00469 2.39e-60 - - - - - - - -
NEFKHMGJ_00470 6.33e-192 pbpE - - V - - - Beta-lactamase
NEFKHMGJ_00471 2.87e-248 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NEFKHMGJ_00472 6.38e-178 - - - H - - - Protein of unknown function (DUF1698)
NEFKHMGJ_00473 4.13e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NEFKHMGJ_00474 1.35e-134 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
NEFKHMGJ_00475 5.97e-101 - - - K - - - Psort location Cytoplasmic, score
NEFKHMGJ_00476 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase N-terminal domain
NEFKHMGJ_00477 5.28e-284 - - - S ko:K07045 - ko00000 Amidohydrolase
NEFKHMGJ_00478 2.77e-316 - - - E - - - Amino acid permease
NEFKHMGJ_00479 4.17e-97 - - - K - - - helix_turn_helix, mercury resistance
NEFKHMGJ_00480 1.31e-208 - - - S - - - reductase
NEFKHMGJ_00481 1.09e-249 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEFKHMGJ_00482 9.54e-78 ydeP - - K - - - Transcriptional regulator, HxlR family
NEFKHMGJ_00483 2.64e-164 - - - S ko:K07090 - ko00000 membrane transporter protein
NEFKHMGJ_00484 3.13e-255 - - - - - - - -
NEFKHMGJ_00485 8.61e-167 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_00486 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NEFKHMGJ_00487 1.15e-162 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NEFKHMGJ_00488 2.7e-258 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEFKHMGJ_00489 4.67e-203 - - - V - - - ATPases associated with a variety of cellular activities
NEFKHMGJ_00490 4.63e-255 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEFKHMGJ_00491 8.65e-136 - - - - - - - -
NEFKHMGJ_00493 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NEFKHMGJ_00494 0.0 ycaM - - E - - - amino acid
NEFKHMGJ_00495 1.79e-303 xylP - - G - - - MFS/sugar transport protein
NEFKHMGJ_00496 1.87e-118 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NEFKHMGJ_00497 3.9e-208 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NEFKHMGJ_00498 4.43e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NEFKHMGJ_00500 1.28e-179 - - - - - - - -
NEFKHMGJ_00502 2.88e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NEFKHMGJ_00503 1.61e-184 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NEFKHMGJ_00504 3.91e-155 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_00505 2.12e-173 - - - - - - - -
NEFKHMGJ_00506 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEFKHMGJ_00507 2.81e-132 - - - S - - - WxL domain surface cell wall-binding
NEFKHMGJ_00508 1.67e-228 - - - S - - - Cell surface protein
NEFKHMGJ_00509 5.86e-65 - - - - - - - -
NEFKHMGJ_00510 1.95e-237 - - - S - - - Leucine-rich repeat (LRR) protein
NEFKHMGJ_00512 1.08e-214 yicL - - EG - - - EamA-like transporter family
NEFKHMGJ_00513 0.0 - - - - - - - -
NEFKHMGJ_00514 2.12e-182 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00515 2.12e-100 - - - S - - - ECF-type riboflavin transporter, S component
NEFKHMGJ_00516 5.86e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NEFKHMGJ_00517 9.2e-210 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NEFKHMGJ_00518 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEFKHMGJ_00519 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00520 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_00521 2.07e-281 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NEFKHMGJ_00522 3.66e-165 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEFKHMGJ_00523 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEFKHMGJ_00524 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_00525 4.39e-273 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NEFKHMGJ_00526 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NEFKHMGJ_00527 3.11e-219 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
NEFKHMGJ_00528 1.86e-316 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NEFKHMGJ_00529 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEFKHMGJ_00530 6.56e-87 - - - - - - - -
NEFKHMGJ_00531 6.52e-98 - - - O - - - OsmC-like protein
NEFKHMGJ_00532 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NEFKHMGJ_00533 9.51e-148 ylbE - - GM - - - NAD(P)H-binding
NEFKHMGJ_00534 1.41e-204 - - - S - - - Aldo/keto reductase family
NEFKHMGJ_00535 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NEFKHMGJ_00536 0.0 - - - S - - - Protein of unknown function (DUF3800)
NEFKHMGJ_00537 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
NEFKHMGJ_00538 4.03e-80 - - - S - - - Protein of unknown function (DUF3021)
NEFKHMGJ_00539 2.14e-89 - - - K - - - LytTr DNA-binding domain
NEFKHMGJ_00540 2.67e-192 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NEFKHMGJ_00541 1.34e-201 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_00542 5.17e-176 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEFKHMGJ_00543 1.4e-148 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NEFKHMGJ_00544 3.05e-69 ybjQ - - S - - - Belongs to the UPF0145 family
NEFKHMGJ_00545 5.98e-121 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NUDIX domain
NEFKHMGJ_00546 5.21e-200 - - - C - - - nadph quinone reductase
NEFKHMGJ_00547 6.6e-312 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NEFKHMGJ_00548 6.58e-226 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NEFKHMGJ_00549 3.15e-153 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
NEFKHMGJ_00550 3.56e-194 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NEFKHMGJ_00552 2.24e-13 - - - - - - - -
NEFKHMGJ_00553 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NEFKHMGJ_00554 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
NEFKHMGJ_00555 2.56e-145 ung2 - - L - - - Uracil-DNA glycosylase
NEFKHMGJ_00556 2.82e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEFKHMGJ_00557 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NEFKHMGJ_00558 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEFKHMGJ_00559 2.8e-171 epsG - - M - - - Glycosyltransferase like family 2
NEFKHMGJ_00561 5.46e-178 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
NEFKHMGJ_00562 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
NEFKHMGJ_00563 1.81e-309 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEFKHMGJ_00564 8.62e-66 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEFKHMGJ_00566 2.83e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEFKHMGJ_00567 2.98e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEFKHMGJ_00568 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NEFKHMGJ_00569 5.62e-211 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEFKHMGJ_00570 2.28e-249 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEFKHMGJ_00571 2.01e-12 - - - - - - - -
NEFKHMGJ_00573 5.34e-108 - - - G - - - PTS system sorbose subfamily IIB component
NEFKHMGJ_00574 2.22e-160 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_00575 3.46e-171 - - - G - - - PTS system mannose/fructose/sorbose family IID component
NEFKHMGJ_00576 1.32e-86 - - - G - - - PTS system fructose IIA component
NEFKHMGJ_00577 5.34e-78 - - - - - - - -
NEFKHMGJ_00578 4.95e-124 - - - S ko:K07090 - ko00000 membrane transporter protein
NEFKHMGJ_00579 3.74e-198 - - - V - - - Beta-lactamase
NEFKHMGJ_00580 6.47e-144 - - - S - - - Domain of unknown function (DUF4867)
NEFKHMGJ_00581 1.69e-207 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_00582 1.64e-236 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NEFKHMGJ_00583 1.85e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NEFKHMGJ_00584 6.59e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
NEFKHMGJ_00585 2.49e-182 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_00586 1.07e-149 - - - S - - - HAD hydrolase, family IA, variant
NEFKHMGJ_00587 3.21e-266 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEFKHMGJ_00588 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NEFKHMGJ_00589 4.79e-21 - - - - - - - -
NEFKHMGJ_00590 5.22e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEFKHMGJ_00591 5.02e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NEFKHMGJ_00592 6.41e-192 - - - I - - - alpha/beta hydrolase fold
NEFKHMGJ_00593 1.22e-155 yrkL - - S - - - Flavodoxin-like fold
NEFKHMGJ_00595 7.75e-115 - - - S - - - Short repeat of unknown function (DUF308)
NEFKHMGJ_00596 1.35e-196 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEFKHMGJ_00597 8.01e-254 - - - - - - - -
NEFKHMGJ_00599 1.83e-150 - - - S ko:K07118 - ko00000 NmrA-like family
NEFKHMGJ_00600 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
NEFKHMGJ_00601 4.54e-215 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
NEFKHMGJ_00602 8.37e-214 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00603 2.78e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEFKHMGJ_00604 4.78e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00605 1.08e-218 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NEFKHMGJ_00606 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NEFKHMGJ_00607 1.9e-231 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
NEFKHMGJ_00608 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
NEFKHMGJ_00609 3.08e-93 - - - S - - - GtrA-like protein
NEFKHMGJ_00610 4.31e-165 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
NEFKHMGJ_00611 1.87e-307 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NEFKHMGJ_00612 1.99e-87 - - - S - - - Belongs to the HesB IscA family
NEFKHMGJ_00613 1.19e-156 ydgI - - C - - - Nitroreductase family
NEFKHMGJ_00614 3.57e-260 lldD 1.13.12.4 - C ko:K00467 ko00620,map00620 ko00000,ko00001,ko01000 IMP dehydrogenase / GMP reductase domain
NEFKHMGJ_00617 1.18e-230 - - - K - - - sequence-specific DNA binding
NEFKHMGJ_00618 6.52e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NEFKHMGJ_00619 5.89e-66 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NEFKHMGJ_00620 1.46e-65 - - - - - - - -
NEFKHMGJ_00621 2.06e-234 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEFKHMGJ_00622 2.38e-74 - - - - - - - -
NEFKHMGJ_00623 6.82e-104 - - - - - - - -
NEFKHMGJ_00624 5.52e-265 XK27_05220 - - S - - - AI-2E family transporter
NEFKHMGJ_00625 1.99e-36 - - - - - - - -
NEFKHMGJ_00626 2.46e-130 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEFKHMGJ_00627 7.08e-96 - - - - - - - -
NEFKHMGJ_00628 3.6e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NEFKHMGJ_00629 5.47e-137 - - - S - - - Flavin reductase like domain
NEFKHMGJ_00630 4.22e-170 - - - - - - - -
NEFKHMGJ_00631 5.82e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEFKHMGJ_00632 2.41e-81 yeaO - - S - - - Protein of unknown function, DUF488
NEFKHMGJ_00633 1.22e-220 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEFKHMGJ_00634 1.4e-205 mleR - - K - - - LysR family
NEFKHMGJ_00635 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NEFKHMGJ_00636 8.81e-218 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NEFKHMGJ_00637 1.6e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEFKHMGJ_00638 2.95e-123 - - - - - - - -
NEFKHMGJ_00639 4.96e-222 - - - K - - - sequence-specific DNA binding
NEFKHMGJ_00640 0.0 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_00641 0.0 pepF - - E - - - Oligopeptidase F
NEFKHMGJ_00642 1.17e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NEFKHMGJ_00643 1.91e-78 - - - - - - - -
NEFKHMGJ_00644 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEFKHMGJ_00645 6.84e-225 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEFKHMGJ_00646 1.03e-77 - - - - - - - -
NEFKHMGJ_00647 2.39e-120 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEFKHMGJ_00648 2.29e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEFKHMGJ_00649 3.04e-154 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NEFKHMGJ_00650 3.72e-100 - - - K - - - Transcriptional regulator
NEFKHMGJ_00651 5.66e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEFKHMGJ_00652 6.13e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NEFKHMGJ_00653 1.3e-201 dkgB - - S - - - reductase
NEFKHMGJ_00654 6.15e-160 - - - - - - - -
NEFKHMGJ_00655 1.26e-207 - - - S - - - Alpha beta hydrolase
NEFKHMGJ_00656 5.25e-149 yviA - - S - - - Protein of unknown function (DUF421)
NEFKHMGJ_00657 5.25e-96 - - - S - - - Protein of unknown function (DUF3290)
NEFKHMGJ_00658 6.91e-283 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NEFKHMGJ_00659 1.19e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEFKHMGJ_00660 1.25e-134 yjbF - - S - - - SNARE associated Golgi protein
NEFKHMGJ_00661 6.95e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEFKHMGJ_00662 1.43e-249 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEFKHMGJ_00663 2.16e-264 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEFKHMGJ_00664 1.64e-287 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEFKHMGJ_00665 1.66e-77 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEFKHMGJ_00666 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEFKHMGJ_00667 1.45e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
NEFKHMGJ_00668 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEFKHMGJ_00669 2.17e-265 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEFKHMGJ_00670 6.26e-305 ytoI - - K - - - DRTGG domain
NEFKHMGJ_00671 7.98e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NEFKHMGJ_00672 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEFKHMGJ_00673 1.17e-218 - - - - - - - -
NEFKHMGJ_00674 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEFKHMGJ_00675 3.9e-264 - - - - - - - -
NEFKHMGJ_00676 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
NEFKHMGJ_00677 1.32e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEFKHMGJ_00678 1.85e-69 yrzB - - S - - - Belongs to the UPF0473 family
NEFKHMGJ_00679 3.45e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEFKHMGJ_00680 3.15e-120 cvpA - - S - - - Colicin V production protein
NEFKHMGJ_00681 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEFKHMGJ_00682 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEFKHMGJ_00683 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEFKHMGJ_00684 1.2e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NEFKHMGJ_00685 1.2e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEFKHMGJ_00686 5.21e-315 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEFKHMGJ_00687 1.61e-107 yslB - - S - - - Protein of unknown function (DUF2507)
NEFKHMGJ_00688 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEFKHMGJ_00689 9.11e-123 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NEFKHMGJ_00690 7.42e-172 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
NEFKHMGJ_00691 5.39e-111 ykuL - - S - - - CBS domain
NEFKHMGJ_00692 2.4e-201 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NEFKHMGJ_00693 2.14e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NEFKHMGJ_00694 7.19e-40 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEFKHMGJ_00695 4.56e-110 ytxH - - S - - - YtxH-like protein
NEFKHMGJ_00696 4.48e-120 yrxA - - S ko:K07105 - ko00000 3H domain
NEFKHMGJ_00697 5.39e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEFKHMGJ_00698 6.12e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NEFKHMGJ_00699 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
NEFKHMGJ_00700 3.04e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NEFKHMGJ_00701 3.4e-173 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEFKHMGJ_00702 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NEFKHMGJ_00703 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEFKHMGJ_00704 3.48e-73 - - - - - - - -
NEFKHMGJ_00705 8.09e-239 yibE - - S - - - overlaps another CDS with the same product name
NEFKHMGJ_00706 6.9e-153 yibF - - S - - - overlaps another CDS with the same product name
NEFKHMGJ_00707 1.94e-148 - - - S - - - Calcineurin-like phosphoesterase
NEFKHMGJ_00708 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEFKHMGJ_00709 5.98e-144 yutD - - S - - - Protein of unknown function (DUF1027)
NEFKHMGJ_00710 4.68e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEFKHMGJ_00711 5.08e-149 - - - S - - - Protein of unknown function (DUF1461)
NEFKHMGJ_00712 3.54e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NEFKHMGJ_00713 6.48e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
NEFKHMGJ_00714 2.61e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NEFKHMGJ_00715 1.8e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEFKHMGJ_00716 2.02e-83 yugI - - J ko:K07570 - ko00000 general stress protein
NEFKHMGJ_00717 1.45e-46 - - - - - - - -
NEFKHMGJ_00718 4.61e-93 - - - S - - - COG NOG38524 non supervised orthologous group
NEFKHMGJ_00745 2.21e-121 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
NEFKHMGJ_00746 0.0 ybeC - - E - - - amino acid
NEFKHMGJ_00747 8.97e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEFKHMGJ_00748 8.94e-250 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEFKHMGJ_00749 2.65e-223 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEFKHMGJ_00750 7.47e-280 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEFKHMGJ_00751 1.15e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
NEFKHMGJ_00752 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEFKHMGJ_00753 2.56e-104 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NEFKHMGJ_00754 1.45e-46 - - - - - - - -
NEFKHMGJ_00755 4.61e-93 - - - S - - - COG NOG38524 non supervised orthologous group
NEFKHMGJ_00759 1.32e-270 int3 - - L - - - Belongs to the 'phage' integrase family
NEFKHMGJ_00761 9.91e-28 - - - - - - - -
NEFKHMGJ_00762 2.98e-112 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NEFKHMGJ_00763 1.4e-24 - - - K - - - Peptidase S24-like
NEFKHMGJ_00764 3.46e-168 - - - S - - - sequence-specific DNA binding
NEFKHMGJ_00765 2.87e-12 - - - - - - - -
NEFKHMGJ_00772 2.4e-104 - - - S - - - Siphovirus Gp157
NEFKHMGJ_00773 4.31e-167 - - - S - - - AAA domain
NEFKHMGJ_00774 1.33e-127 - - - S - - - Protein of unknown function (DUF669)
NEFKHMGJ_00775 7.16e-121 - - - S - - - calcium ion binding
NEFKHMGJ_00776 7.78e-157 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NEFKHMGJ_00778 2.3e-44 - - - - - - - -
NEFKHMGJ_00779 2.27e-86 - - - S - - - magnesium ion binding
NEFKHMGJ_00781 1.13e-157 - - - S - - - DNA methylation
NEFKHMGJ_00783 2.99e-42 - - - S - - - Protein of unknown function (DUF1642)
NEFKHMGJ_00784 7.07e-38 - - - - - - - -
NEFKHMGJ_00787 4.4e-101 - - - - - - - -
NEFKHMGJ_00788 6.97e-28 - - - - - - - -
NEFKHMGJ_00790 5.47e-301 - - - - - - - -
NEFKHMGJ_00791 1.91e-125 - - - S - - - HNH endonuclease
NEFKHMGJ_00792 2.99e-66 - - - - - - - -
NEFKHMGJ_00793 1.26e-91 - - - S - - - HNH endonuclease
NEFKHMGJ_00794 2.95e-101 - - - S - - - Phage terminase, small subunit
NEFKHMGJ_00795 0.0 - - - S - - - Phage Terminase
NEFKHMGJ_00797 6.69e-283 - - - S - - - Phage portal protein
NEFKHMGJ_00798 1.34e-139 - - - S - - - peptidase activity
NEFKHMGJ_00799 2.1e-257 - - - S - - - peptidase activity
NEFKHMGJ_00800 4.67e-37 - - - S - - - peptidase activity
NEFKHMGJ_00801 4.38e-36 - - - S - - - Phage gp6-like head-tail connector protein
NEFKHMGJ_00802 6.82e-53 - - - S - - - Phage head-tail joining protein
NEFKHMGJ_00803 8.05e-88 - - - S - - - exonuclease activity
NEFKHMGJ_00804 3.25e-39 - - - - - - - -
NEFKHMGJ_00805 1.89e-93 - - - S - - - Pfam:Phage_TTP_1
NEFKHMGJ_00806 2.72e-27 - - - - - - - -
NEFKHMGJ_00807 0.0 - - - S - - - peptidoglycan catabolic process
NEFKHMGJ_00808 0.0 - - - S - - - Phage tail protein
NEFKHMGJ_00809 0.0 - - - S - - - peptidoglycan catabolic process
NEFKHMGJ_00810 6.88e-71 - - - - - - - -
NEFKHMGJ_00812 4.74e-70 - - - - - - - -
NEFKHMGJ_00813 6.64e-80 hol - - S - - - Bacteriophage holin
NEFKHMGJ_00814 5.28e-283 - - - M - - - Glycosyl hydrolases family 25
NEFKHMGJ_00816 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_00818 2.99e-140 - - - - - - - -
NEFKHMGJ_00819 1.66e-269 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEFKHMGJ_00820 0.0 mdr - - EGP - - - Major Facilitator
NEFKHMGJ_00821 1.97e-106 - - - K - - - MerR HTH family regulatory protein
NEFKHMGJ_00822 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEFKHMGJ_00823 1.3e-155 - - - S - - - Domain of unknown function (DUF4811)
NEFKHMGJ_00824 2.12e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NEFKHMGJ_00825 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEFKHMGJ_00826 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEFKHMGJ_00827 3.27e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEFKHMGJ_00828 8.09e-48 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NEFKHMGJ_00829 9.98e-182 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEFKHMGJ_00830 6.85e-122 - - - F - - - NUDIX domain
NEFKHMGJ_00832 3.41e-112 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NEFKHMGJ_00833 1.49e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEFKHMGJ_00834 1.33e-281 cpdA - - S - - - Calcineurin-like phosphoesterase
NEFKHMGJ_00835 1.19e-50 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NEFKHMGJ_00836 1.81e-309 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NEFKHMGJ_00837 1.22e-272 coiA - - S ko:K06198 - ko00000 Competence protein
NEFKHMGJ_00838 8.12e-151 yjbH - - Q - - - Thioredoxin
NEFKHMGJ_00839 3.46e-136 - - - S - - - CYTH
NEFKHMGJ_00840 3.41e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEFKHMGJ_00841 2.24e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEFKHMGJ_00842 2.03e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEFKHMGJ_00843 1.14e-257 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEFKHMGJ_00844 2.92e-142 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NEFKHMGJ_00845 2.29e-185 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEFKHMGJ_00846 4.44e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NEFKHMGJ_00847 7.55e-82 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEFKHMGJ_00848 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEFKHMGJ_00849 9.97e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEFKHMGJ_00850 5.57e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEFKHMGJ_00851 2.32e-198 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NEFKHMGJ_00852 6.48e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEFKHMGJ_00853 8.84e-93 - - - S - - - Protein of unknown function (DUF1149)
NEFKHMGJ_00854 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEFKHMGJ_00855 1.74e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
NEFKHMGJ_00856 3.94e-309 ymfH - - S - - - Peptidase M16
NEFKHMGJ_00857 1.22e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEFKHMGJ_00858 4.37e-165 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NEFKHMGJ_00859 2.26e-134 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEFKHMGJ_00860 4.78e-290 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NEFKHMGJ_00861 1.41e-241 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEFKHMGJ_00862 3.84e-17 - - - - - - - -
NEFKHMGJ_00863 0.0 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NEFKHMGJ_00864 6.12e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NEFKHMGJ_00865 1.51e-297 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NEFKHMGJ_00866 1.8e-117 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NEFKHMGJ_00867 7.96e-127 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEFKHMGJ_00868 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEFKHMGJ_00869 6.43e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEFKHMGJ_00870 2.59e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
NEFKHMGJ_00871 4.17e-204 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NEFKHMGJ_00872 7.12e-254 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NEFKHMGJ_00873 9.79e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEFKHMGJ_00874 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEFKHMGJ_00875 4.5e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEFKHMGJ_00876 1.56e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEFKHMGJ_00877 3.55e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NEFKHMGJ_00878 6.38e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEFKHMGJ_00879 1.18e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEFKHMGJ_00880 1.33e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEFKHMGJ_00881 0.0 yvlB - - S - - - Putative adhesin
NEFKHMGJ_00882 4.06e-48 - - - - - - - -
NEFKHMGJ_00883 2.28e-61 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NEFKHMGJ_00884 5.82e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEFKHMGJ_00885 2e-201 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEFKHMGJ_00886 2.2e-250 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NEFKHMGJ_00887 4.84e-229 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEFKHMGJ_00888 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEFKHMGJ_00889 7.27e-108 - - - T - - - Transcriptional regulatory protein, C terminal
NEFKHMGJ_00890 7.64e-142 - - - T - - - His Kinase A (phosphoacceptor) domain
NEFKHMGJ_00891 4.02e-116 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00892 2.85e-300 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEFKHMGJ_00893 4.68e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NEFKHMGJ_00894 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEFKHMGJ_00895 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEFKHMGJ_00896 6.02e-110 - - - S - - - Short repeat of unknown function (DUF308)
NEFKHMGJ_00897 1.21e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NEFKHMGJ_00898 2.87e-246 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NEFKHMGJ_00899 3.36e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NEFKHMGJ_00900 6.45e-105 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NEFKHMGJ_00901 1.71e-131 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEFKHMGJ_00903 2.73e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NEFKHMGJ_00904 2.99e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEFKHMGJ_00905 1.52e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NEFKHMGJ_00906 8.05e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEFKHMGJ_00907 2.39e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEFKHMGJ_00908 2.17e-81 - - - - - - - -
NEFKHMGJ_00909 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEFKHMGJ_00910 1.48e-78 - - - - - - - -
NEFKHMGJ_00911 2.92e-42 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEFKHMGJ_00912 1.29e-177 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NEFKHMGJ_00913 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEFKHMGJ_00914 9.03e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEFKHMGJ_00915 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEFKHMGJ_00916 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEFKHMGJ_00917 8.3e-150 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEFKHMGJ_00918 5.27e-64 - - - - - - - -
NEFKHMGJ_00920 1.03e-305 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
NEFKHMGJ_00921 5.23e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEFKHMGJ_00922 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_00923 1.72e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
NEFKHMGJ_00924 6.04e-249 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_00925 1.6e-133 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
NEFKHMGJ_00926 5.33e-119 - - - - - - - -
NEFKHMGJ_00927 4.87e-204 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEFKHMGJ_00928 4.68e-168 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEFKHMGJ_00929 1.82e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NEFKHMGJ_00930 4.87e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NEFKHMGJ_00931 5.34e-213 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_00932 1.88e-274 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEFKHMGJ_00933 1.9e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEFKHMGJ_00934 5.5e-190 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NEFKHMGJ_00935 3.91e-201 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEFKHMGJ_00936 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NEFKHMGJ_00937 4.84e-125 - - - K - - - Cupin domain
NEFKHMGJ_00938 9.49e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEFKHMGJ_00939 2.13e-191 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00940 1.67e-185 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_00941 5.98e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_00944 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
NEFKHMGJ_00945 3.12e-151 - - - K - - - Transcriptional regulator
NEFKHMGJ_00946 1.02e-244 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_00947 4.27e-167 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEFKHMGJ_00948 2.69e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEFKHMGJ_00949 2.39e-221 ybbR - - S - - - YbbR-like protein
NEFKHMGJ_00950 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEFKHMGJ_00951 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEFKHMGJ_00952 0.0 pepF2 - - E - - - Oligopeptidase F
NEFKHMGJ_00953 5.18e-119 - - - S - - - VanZ like family
NEFKHMGJ_00954 1.75e-170 yebC - - K - - - Transcriptional regulatory protein
NEFKHMGJ_00955 6.78e-175 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NEFKHMGJ_00956 2.08e-215 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NEFKHMGJ_00957 2.85e-64 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
NEFKHMGJ_00959 3.45e-63 - - - - - - - -
NEFKHMGJ_00960 4.66e-100 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
NEFKHMGJ_00961 3.74e-59 - - - - - - - -
NEFKHMGJ_00962 2.23e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NEFKHMGJ_00963 4.7e-94 - - - - - - - -
NEFKHMGJ_00964 1.74e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEFKHMGJ_00965 1.34e-184 arbV - - I - - - Phosphate acyltransferases
NEFKHMGJ_00966 6.75e-211 arbx - - M - - - Glycosyl transferase family 8
NEFKHMGJ_00967 8.68e-229 arbY - - M - - - family 8
NEFKHMGJ_00968 1.45e-207 arbZ - - I - - - Phosphate acyltransferases
NEFKHMGJ_00969 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEFKHMGJ_00971 1.55e-91 - - - S - - - SdpI/YhfL protein family
NEFKHMGJ_00972 2.91e-125 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NEFKHMGJ_00973 0.0 yclK - - T - - - Histidine kinase
NEFKHMGJ_00974 1.34e-121 - - - S - - - acetyltransferase
NEFKHMGJ_00975 2.21e-42 - - - - - - - -
NEFKHMGJ_00976 1.49e-93 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NEFKHMGJ_00977 6.43e-106 - - - - - - - -
NEFKHMGJ_00978 1.41e-77 - - - - - - - -
NEFKHMGJ_00979 1.91e-316 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NEFKHMGJ_00981 2.29e-244 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEFKHMGJ_00983 2.22e-278 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEFKHMGJ_00984 2.35e-169 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
NEFKHMGJ_00985 1.92e-53 - - - S - - - Bacterial protein of unknown function (DUF898)
NEFKHMGJ_00986 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NEFKHMGJ_00987 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEFKHMGJ_00988 2.36e-260 camS - - S - - - sex pheromone
NEFKHMGJ_00989 1.26e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEFKHMGJ_00990 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEFKHMGJ_00991 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEFKHMGJ_00992 1.22e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NEFKHMGJ_00993 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEFKHMGJ_00994 1.45e-277 yttB - - EGP - - - Major Facilitator
NEFKHMGJ_00995 4.65e-189 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEFKHMGJ_00996 4.22e-211 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
NEFKHMGJ_00997 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEFKHMGJ_00998 6.68e-98 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_00999 2.75e-211 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NEFKHMGJ_01000 7.91e-166 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NEFKHMGJ_01001 1.05e-40 - - - - - - - -
NEFKHMGJ_01002 2.01e-135 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEFKHMGJ_01003 3.83e-79 - - - S - - - Protein of unknown function (DUF1093)
NEFKHMGJ_01004 3.98e-81 - - - S - - - Domain of unknown function (DUF4828)
NEFKHMGJ_01005 1.55e-226 mocA - - S - - - Oxidoreductase
NEFKHMGJ_01006 6.94e-299 yfmL - - L - - - DEAD DEAH box helicase
NEFKHMGJ_01007 1.19e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEFKHMGJ_01008 3.16e-93 - - - S - - - Domain of unknown function (DUF3284)
NEFKHMGJ_01010 1.66e-07 - - - - - - - -
NEFKHMGJ_01011 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEFKHMGJ_01012 5.51e-304 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
NEFKHMGJ_01013 3.46e-143 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_01014 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NEFKHMGJ_01015 2.47e-227 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NEFKHMGJ_01016 3.71e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
NEFKHMGJ_01017 4.73e-204 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NEFKHMGJ_01018 2.66e-247 - - - M - - - Glycosyltransferase like family 2
NEFKHMGJ_01020 2.12e-40 - - - - - - - -
NEFKHMGJ_01021 8.56e-157 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
NEFKHMGJ_01022 1.09e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NEFKHMGJ_01023 9.26e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEFKHMGJ_01025 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_01026 0.0 - - - S - - - Bacterial membrane protein YfhO
NEFKHMGJ_01027 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
NEFKHMGJ_01028 1.22e-219 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NEFKHMGJ_01029 5.01e-142 - - - - - - - -
NEFKHMGJ_01030 9.9e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NEFKHMGJ_01031 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NEFKHMGJ_01032 3.64e-37 - - - T - - - PFAM SpoVT AbrB
NEFKHMGJ_01033 4.85e-106 yvbK - - K - - - GNAT family
NEFKHMGJ_01034 1.51e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NEFKHMGJ_01035 6.51e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEFKHMGJ_01036 5.34e-304 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NEFKHMGJ_01037 2.43e-263 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEFKHMGJ_01038 5.79e-316 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEFKHMGJ_01039 4.26e-133 - - - - - - - -
NEFKHMGJ_01040 3.36e-166 - - - - - - - -
NEFKHMGJ_01041 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEFKHMGJ_01042 3.74e-142 vanZ - - V - - - VanZ like family
NEFKHMGJ_01043 1.1e-194 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NEFKHMGJ_01044 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEFKHMGJ_01045 1.21e-287 - - - L - - - Pfam:Integrase_AP2
NEFKHMGJ_01047 3.79e-226 - - - - - - - -
NEFKHMGJ_01048 1.19e-100 - - - S - - - Domain of unknown function (DUF5067)
NEFKHMGJ_01049 3.3e-97 - - - E - - - Zn peptidase
NEFKHMGJ_01050 2.45e-72 - - - K - - - Helix-turn-helix domain
NEFKHMGJ_01051 3.62e-46 - - - K - - - Helix-turn-helix domain
NEFKHMGJ_01053 4.05e-97 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
NEFKHMGJ_01054 3.67e-126 - - - - - - - -
NEFKHMGJ_01056 2.86e-20 - - - - - - - -
NEFKHMGJ_01059 3.83e-198 - - - L ko:K07455 - ko00000,ko03400 RecT family
NEFKHMGJ_01060 8.62e-171 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NEFKHMGJ_01061 6.05e-204 - - - L - - - Replication initiation and membrane attachment
NEFKHMGJ_01062 2.85e-97 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEFKHMGJ_01063 4.62e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEFKHMGJ_01064 4.02e-89 - - - - - - - -
NEFKHMGJ_01065 1.23e-48 - - - - - - - -
NEFKHMGJ_01066 1.32e-85 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NEFKHMGJ_01067 1.54e-29 - - - - - - - -
NEFKHMGJ_01068 1.79e-117 - - - S - - - Protein of unknown function (DUF1642)
NEFKHMGJ_01069 3.71e-45 - - - - - - - -
NEFKHMGJ_01072 1.55e-101 - - - - - - - -
NEFKHMGJ_01073 2.71e-200 - - - - - - - -
NEFKHMGJ_01074 2.41e-281 - - - S - - - GcrA cell cycle regulator
NEFKHMGJ_01075 4.41e-68 - - - - - - - -
NEFKHMGJ_01076 1.81e-110 - - - L ko:K07474 - ko00000 Terminase small subunit
NEFKHMGJ_01077 0.0 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
NEFKHMGJ_01078 3.5e-316 - - - S - - - Phage portal protein
NEFKHMGJ_01079 2.94e-99 - - - S - - - head morphogenesis protein, SPP1 gp7 family
NEFKHMGJ_01080 7.29e-137 - - - S - - - Domain of unknown function (DUF4355)
NEFKHMGJ_01081 3.4e-231 gpG - - - - - - -
NEFKHMGJ_01082 8.8e-72 - - - S - - - Phage gp6-like head-tail connector protein
NEFKHMGJ_01083 2.51e-62 - - - - - - - -
NEFKHMGJ_01084 8.92e-75 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NEFKHMGJ_01085 6.75e-92 - - - S - - - Protein of unknown function (DUF3168)
NEFKHMGJ_01086 1.52e-134 - - - S - - - Phage tail tube protein
NEFKHMGJ_01087 3.97e-66 - - - S - - - Phage tail assembly chaperone protein, TAC
NEFKHMGJ_01088 1.57e-73 - - - - - - - -
NEFKHMGJ_01089 0.0 - - - S - - - phage tail tape measure protein
NEFKHMGJ_01090 0.0 - - - S - - - Phage tail protein
NEFKHMGJ_01091 0.0 - - - S - - - cellulase activity
NEFKHMGJ_01093 9.18e-60 - - - - - - - -
NEFKHMGJ_01094 7.1e-78 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NEFKHMGJ_01095 2.8e-277 - - - M - - - Glycosyl hydrolases family 25
NEFKHMGJ_01097 4.12e-61 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NEFKHMGJ_01098 8.47e-182 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NEFKHMGJ_01099 6.23e-106 - - - S - - - Pfam Transposase IS66
NEFKHMGJ_01100 2.76e-294 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
NEFKHMGJ_01101 4.43e-220 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NEFKHMGJ_01102 2.6e-106 guaD - - FJ - - - MafB19-like deaminase
NEFKHMGJ_01107 6.11e-216 - - - L - - - PFAM transposase, IS4 family protein
NEFKHMGJ_01108 3.9e-13 - - - L - - - PFAM transposase, IS4 family protein
NEFKHMGJ_01111 1.56e-25 - - - - - - - -
NEFKHMGJ_01112 3.25e-246 yttB - - EGP - - - Major Facilitator
NEFKHMGJ_01113 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEFKHMGJ_01116 5.42e-170 pgm7 - - G - - - Phosphoglycerate mutase family
NEFKHMGJ_01117 1.29e-155 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_01118 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01119 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEFKHMGJ_01120 1.24e-179 - - - S - - - NADPH-dependent FMN reductase
NEFKHMGJ_01121 1.31e-208 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NEFKHMGJ_01122 1.72e-243 ampC - - V - - - Beta-lactamase
NEFKHMGJ_01123 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NEFKHMGJ_01124 8.22e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NEFKHMGJ_01125 3.51e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEFKHMGJ_01126 9.85e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEFKHMGJ_01127 1.73e-246 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEFKHMGJ_01128 5.24e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEFKHMGJ_01129 1.51e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEFKHMGJ_01130 2.38e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEFKHMGJ_01131 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEFKHMGJ_01132 1.03e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEFKHMGJ_01133 3.77e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEFKHMGJ_01134 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEFKHMGJ_01135 1.2e-209 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEFKHMGJ_01136 1.52e-15 - - - - - - - -
NEFKHMGJ_01137 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEFKHMGJ_01138 6.51e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NEFKHMGJ_01139 2.5e-43 - - - S - - - Protein of unknown function (DUF1146)
NEFKHMGJ_01140 2.13e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NEFKHMGJ_01141 5.48e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
NEFKHMGJ_01142 1.62e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NEFKHMGJ_01143 2.92e-42 - - - S - - - Protein of unknown function (DUF2969)
NEFKHMGJ_01144 1.35e-283 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NEFKHMGJ_01145 2.34e-62 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NEFKHMGJ_01146 5.17e-272 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEFKHMGJ_01147 1.56e-189 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEFKHMGJ_01148 5.03e-191 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEFKHMGJ_01149 1.03e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEFKHMGJ_01150 7.93e-151 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01151 2.4e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NEFKHMGJ_01152 1.72e-243 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NEFKHMGJ_01153 1.76e-284 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEFKHMGJ_01154 9.59e-101 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NEFKHMGJ_01155 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NEFKHMGJ_01156 2.14e-36 - - - - - - - -
NEFKHMGJ_01157 8.1e-87 - - - S - - - Protein of unknown function (DUF1694)
NEFKHMGJ_01158 9.73e-228 - - - S - - - Protein of unknown function (DUF2785)
NEFKHMGJ_01159 6.18e-206 - - - K - - - Helix-turn-helix XRE-family like proteins
NEFKHMGJ_01160 6.47e-110 uspA - - T - - - universal stress protein
NEFKHMGJ_01161 8.18e-53 - - - - - - - -
NEFKHMGJ_01162 0.000138 - - - - - - - -
NEFKHMGJ_01163 7.51e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEFKHMGJ_01164 0.0 - 6.3.2.2 - M ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain protein
NEFKHMGJ_01165 3.84e-94 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NEFKHMGJ_01166 4.72e-141 yktB - - S - - - Belongs to the UPF0637 family
NEFKHMGJ_01167 2.93e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NEFKHMGJ_01168 4.1e-192 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEFKHMGJ_01169 1.88e-154 - - - G - - - Phosphoglycerate mutase family
NEFKHMGJ_01170 4.68e-197 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEFKHMGJ_01171 3.75e-215 - - - IQ - - - NAD dependent epimerase/dehydratase family
NEFKHMGJ_01172 1.19e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEFKHMGJ_01173 1.14e-170 - - - F - - - deoxynucleoside kinase
NEFKHMGJ_01174 4.72e-202 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
NEFKHMGJ_01175 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEFKHMGJ_01176 1.15e-204 - - - T - - - GHKL domain
NEFKHMGJ_01177 1.69e-87 - - - T - - - Transcriptional regulatory protein, C terminal
NEFKHMGJ_01178 1.9e-52 - - - T - - - Transcriptional regulatory protein, C terminal
NEFKHMGJ_01179 7.56e-214 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEFKHMGJ_01180 1.03e-164 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEFKHMGJ_01181 1.11e-203 - - - K - - - Transcriptional regulator
NEFKHMGJ_01182 2.15e-99 yphH - - S - - - Cupin domain
NEFKHMGJ_01183 1.3e-71 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEFKHMGJ_01184 1.95e-47 - - - - - - - -
NEFKHMGJ_01185 4.06e-35 - - - K - - - Psort location Cytoplasmic, score
NEFKHMGJ_01186 2.71e-122 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
NEFKHMGJ_01187 3.47e-105 - - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEFKHMGJ_01188 1.72e-208 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01189 2.31e-110 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01190 2.82e-150 degV - - S - - - Uncharacterised protein, DegV family COG1307
NEFKHMGJ_01191 7.51e-145 - - - - - - - -
NEFKHMGJ_01192 1.45e-133 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NEFKHMGJ_01193 8.4e-259 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEFKHMGJ_01194 3.44e-162 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEFKHMGJ_01196 1.72e-266 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEFKHMGJ_01197 5e-194 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_01198 0.0 - - - - - - - -
NEFKHMGJ_01199 2.18e-221 - - - - - - - -
NEFKHMGJ_01200 9.09e-82 - - - S - - - Protein of unknown function C-terminus (DUF2399)
NEFKHMGJ_01201 1.83e-106 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01202 7.23e-89 - - - - - - - -
NEFKHMGJ_01203 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NEFKHMGJ_01204 5.37e-106 - - - - - - - -
NEFKHMGJ_01205 3.99e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NEFKHMGJ_01206 5.59e-290 - - - E - - - Amino acid permease
NEFKHMGJ_01207 2.14e-118 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEFKHMGJ_01208 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEFKHMGJ_01209 2.89e-110 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NEFKHMGJ_01210 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEFKHMGJ_01211 1.89e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEFKHMGJ_01212 1.73e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEFKHMGJ_01213 5.65e-149 - - - K ko:K01926 - ko00000,ko03000 CoA binding domain
NEFKHMGJ_01214 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEFKHMGJ_01215 1.03e-303 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEFKHMGJ_01216 5.92e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
NEFKHMGJ_01217 2.01e-151 radC - - L ko:K03630 - ko00000 DNA repair protein
NEFKHMGJ_01218 6.84e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NEFKHMGJ_01219 6.56e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NEFKHMGJ_01220 2.04e-111 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NEFKHMGJ_01221 8.93e-144 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEFKHMGJ_01222 4.99e-181 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NEFKHMGJ_01223 2.77e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01224 7.44e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NEFKHMGJ_01225 1.1e-191 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEFKHMGJ_01226 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEFKHMGJ_01227 4.32e-14 - - - S - - - Protein of unknown function (DUF4044)
NEFKHMGJ_01228 6.71e-10 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEFKHMGJ_01229 1.49e-70 - - - - - - - -
NEFKHMGJ_01230 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEFKHMGJ_01231 5.56e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEFKHMGJ_01232 8.26e-80 ftsL - - D - - - cell division protein FtsL
NEFKHMGJ_01233 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEFKHMGJ_01234 1.82e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEFKHMGJ_01235 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEFKHMGJ_01236 1.56e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEFKHMGJ_01237 4.67e-196 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEFKHMGJ_01238 2.11e-307 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEFKHMGJ_01239 1.09e-290 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEFKHMGJ_01240 5.95e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEFKHMGJ_01241 6.86e-60 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
NEFKHMGJ_01242 1.91e-185 ylmH - - S - - - S4 domain protein
NEFKHMGJ_01243 8.06e-114 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
NEFKHMGJ_01244 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEFKHMGJ_01245 2.98e-49 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NEFKHMGJ_01246 6.09e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEFKHMGJ_01247 0.0 ydiC1 - - EGP - - - Major Facilitator
NEFKHMGJ_01248 6e-268 yaaN - - P - - - Toxic anion resistance protein (TelA)
NEFKHMGJ_01249 1.39e-151 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NEFKHMGJ_01250 6.34e-127 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NEFKHMGJ_01251 1.36e-46 - - - - - - - -
NEFKHMGJ_01252 3.94e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEFKHMGJ_01253 1.39e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEFKHMGJ_01254 3.61e-77 XK27_04120 - - S - - - Putative amino acid metabolism
NEFKHMGJ_01255 0.0 uvrA2 - - L - - - ABC transporter
NEFKHMGJ_01256 1.39e-276 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEFKHMGJ_01257 9.46e-159 pgm6 - - G - - - phosphoglycerate mutase
NEFKHMGJ_01258 3.38e-149 - - - S - - - repeat protein
NEFKHMGJ_01259 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEFKHMGJ_01260 1.36e-310 - - - S - - - Sterol carrier protein domain
NEFKHMGJ_01261 2.93e-235 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NEFKHMGJ_01262 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEFKHMGJ_01263 4.07e-43 ykzG - - S - - - Belongs to the UPF0356 family
NEFKHMGJ_01265 2.52e-97 - - - - - - - -
NEFKHMGJ_01266 1.83e-35 - - - - - - - -
NEFKHMGJ_01267 1.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEFKHMGJ_01268 1.64e-173 - - - S - - - E1-E2 ATPase
NEFKHMGJ_01269 1.36e-265 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NEFKHMGJ_01270 4.67e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NEFKHMGJ_01271 1.87e-314 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEFKHMGJ_01272 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NEFKHMGJ_01273 2.05e-200 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NEFKHMGJ_01274 8.74e-62 yktA - - S - - - Belongs to the UPF0223 family
NEFKHMGJ_01275 1.06e-186 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NEFKHMGJ_01276 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NEFKHMGJ_01277 3.76e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEFKHMGJ_01278 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEFKHMGJ_01279 2.84e-75 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NEFKHMGJ_01280 1.01e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NEFKHMGJ_01281 2.44e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEFKHMGJ_01282 1.01e-247 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NEFKHMGJ_01283 3.25e-146 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NEFKHMGJ_01284 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NEFKHMGJ_01285 2.02e-247 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NEFKHMGJ_01286 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEFKHMGJ_01287 1.6e-150 - - - - - - - -
NEFKHMGJ_01288 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEFKHMGJ_01289 4.87e-206 - - - S - - - Tetratricopeptide repeat
NEFKHMGJ_01290 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEFKHMGJ_01291 5.68e-109 - - - M - - - Protein of unknown function (DUF3737)
NEFKHMGJ_01292 1.14e-168 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
NEFKHMGJ_01293 1.12e-82 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEFKHMGJ_01294 2.93e-85 - - - K - - - helix_turn_helix, mercury resistance
NEFKHMGJ_01295 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NEFKHMGJ_01296 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_01297 2.78e-269 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEFKHMGJ_01298 5.9e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEFKHMGJ_01299 1.21e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NEFKHMGJ_01300 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
NEFKHMGJ_01301 2.34e-28 - - - - - - - -
NEFKHMGJ_01302 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01303 1.33e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01304 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEFKHMGJ_01306 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NEFKHMGJ_01307 5.35e-216 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEFKHMGJ_01308 4.8e-171 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_01309 1.29e-297 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEFKHMGJ_01310 0.0 oatA - - I - - - Acyltransferase
NEFKHMGJ_01311 3.56e-233 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEFKHMGJ_01312 4.46e-182 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NEFKHMGJ_01313 5.47e-63 - - - S - - - Lipopolysaccharide assembly protein A domain
NEFKHMGJ_01314 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEFKHMGJ_01315 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NEFKHMGJ_01316 7.94e-122 - - - K - - - Domain of unknown function (DUF1836)
NEFKHMGJ_01317 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NEFKHMGJ_01318 7.5e-188 - - - - - - - -
NEFKHMGJ_01319 2.06e-38 - - - S - - - Protein of unknown function (DUF2929)
NEFKHMGJ_01320 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NEFKHMGJ_01321 9e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEFKHMGJ_01322 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NEFKHMGJ_01323 6.13e-95 ytwI - - S - - - Protein of unknown function (DUF441)
NEFKHMGJ_01324 1.47e-208 yitL - - S ko:K00243 - ko00000 S1 domain
NEFKHMGJ_01325 1.21e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NEFKHMGJ_01326 2.81e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEFKHMGJ_01327 8.93e-163 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEFKHMGJ_01328 1.1e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEFKHMGJ_01329 3.03e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEFKHMGJ_01330 4.54e-125 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEFKHMGJ_01331 4.03e-61 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
NEFKHMGJ_01332 5.09e-238 - - - S - - - Helix-turn-helix domain
NEFKHMGJ_01333 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEFKHMGJ_01334 7.22e-86 - - - M - - - Lysin motif
NEFKHMGJ_01335 4.45e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NEFKHMGJ_01336 6.19e-300 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NEFKHMGJ_01337 3.67e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NEFKHMGJ_01338 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEFKHMGJ_01339 1.64e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NEFKHMGJ_01340 2.95e-207 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEFKHMGJ_01341 2.25e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEFKHMGJ_01342 5.96e-110 - - - - - - - -
NEFKHMGJ_01343 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01344 2.17e-246 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEFKHMGJ_01345 6.29e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEFKHMGJ_01346 4.5e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NEFKHMGJ_01347 1.18e-191 WQ51_01275 - - S - - - EDD domain protein, DegV family
NEFKHMGJ_01348 2.24e-201 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NEFKHMGJ_01349 1.76e-146 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NEFKHMGJ_01350 2.34e-124 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEFKHMGJ_01351 2.52e-55 yozE - - S - - - Belongs to the UPF0346 family
NEFKHMGJ_01352 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NEFKHMGJ_01353 1.11e-74 - - - S - - - Psort location Cytoplasmic, score
NEFKHMGJ_01354 2.8e-12 - - - - - - - -
NEFKHMGJ_01355 3.35e-152 - - - S - - - Domain of unknown function (DUF4918)
NEFKHMGJ_01356 1.84e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEFKHMGJ_01357 2.79e-176 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEFKHMGJ_01358 4.28e-185 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NEFKHMGJ_01359 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEFKHMGJ_01360 3.78e-316 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEFKHMGJ_01361 5.78e-215 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NEFKHMGJ_01362 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEFKHMGJ_01363 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEFKHMGJ_01364 7.64e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NEFKHMGJ_01365 5.07e-143 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEFKHMGJ_01366 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEFKHMGJ_01367 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEFKHMGJ_01368 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NEFKHMGJ_01369 3.64e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEFKHMGJ_01370 1.15e-235 - - - K - - - LysR substrate binding domain
NEFKHMGJ_01371 1.6e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NEFKHMGJ_01372 1.36e-265 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NEFKHMGJ_01373 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
NEFKHMGJ_01374 7.18e-49 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
NEFKHMGJ_01375 1.42e-104 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01376 6.54e-38 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01377 1.95e-221 - - - T - - - Histidine kinase-like ATPases
NEFKHMGJ_01378 4.31e-165 - - - T - - - Transcriptional regulatory protein, C terminal
NEFKHMGJ_01379 2.23e-279 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NEFKHMGJ_01380 7.37e-90 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01381 1.22e-93 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01382 1.76e-145 - - - C - - - Nitroreductase family
NEFKHMGJ_01383 1.97e-189 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
NEFKHMGJ_01384 5.29e-262 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEFKHMGJ_01385 5.01e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NEFKHMGJ_01386 3.38e-76 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEFKHMGJ_01387 8.59e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEFKHMGJ_01388 2.78e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEFKHMGJ_01389 4.89e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEFKHMGJ_01390 1.21e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NEFKHMGJ_01391 8.89e-288 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEFKHMGJ_01392 7.73e-139 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEFKHMGJ_01393 2.12e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEFKHMGJ_01394 2.07e-262 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Cys/Met metabolism PLP-dependent enzyme
NEFKHMGJ_01395 1.55e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NEFKHMGJ_01396 5.1e-206 - - - S - - - EDD domain protein, DegV family
NEFKHMGJ_01398 0.0 FbpA - - K - - - Fibronectin-binding protein
NEFKHMGJ_01399 1.43e-67 - - - S - - - MazG-like family
NEFKHMGJ_01400 1.91e-245 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NEFKHMGJ_01401 1.9e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEFKHMGJ_01402 1.27e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEFKHMGJ_01403 7.99e-195 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEFKHMGJ_01404 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEFKHMGJ_01405 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEFKHMGJ_01406 1.94e-306 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEFKHMGJ_01407 1.44e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEFKHMGJ_01408 3.31e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NEFKHMGJ_01409 3.67e-126 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEFKHMGJ_01410 1.74e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEFKHMGJ_01411 5.71e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEFKHMGJ_01412 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NEFKHMGJ_01413 1.16e-83 - - - S - - - Family of unknown function (DUF5322)
NEFKHMGJ_01414 2.28e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NEFKHMGJ_01415 9.94e-142 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NEFKHMGJ_01416 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEFKHMGJ_01417 1.9e-72 - - - - - - - -
NEFKHMGJ_01418 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01419 1.76e-51 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NEFKHMGJ_01420 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEFKHMGJ_01421 1.46e-240 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEFKHMGJ_01422 6.22e-211 lysR - - K - - - Transcriptional regulator
NEFKHMGJ_01423 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEFKHMGJ_01424 1.66e-247 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NEFKHMGJ_01425 5.13e-46 - - - - - - - -
NEFKHMGJ_01426 4.44e-223 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEFKHMGJ_01427 7.13e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NEFKHMGJ_01428 5.37e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEFKHMGJ_01429 2.19e-136 ypsA - - S - - - Belongs to the UPF0398 family
NEFKHMGJ_01430 1.71e-155 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEFKHMGJ_01431 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NEFKHMGJ_01432 7.79e-112 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NEFKHMGJ_01433 1.34e-147 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEFKHMGJ_01434 3.31e-143 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NEFKHMGJ_01435 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEFKHMGJ_01436 2.32e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NEFKHMGJ_01437 8.92e-111 ypmB - - S - - - Protein conserved in bacteria
NEFKHMGJ_01439 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NEFKHMGJ_01440 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NEFKHMGJ_01441 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEFKHMGJ_01442 3.59e-213 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NEFKHMGJ_01443 5.2e-229 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NEFKHMGJ_01444 3.44e-239 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEFKHMGJ_01446 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NEFKHMGJ_01447 3.79e-223 - - - - - - - -
NEFKHMGJ_01448 5.06e-181 - - - - - - - -
NEFKHMGJ_01449 4.01e-80 yitW - - S - - - Iron-sulfur cluster assembly protein
NEFKHMGJ_01450 1.05e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NEFKHMGJ_01451 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 (ABC) transporter
NEFKHMGJ_01452 0.0 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_01453 1.57e-188 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEFKHMGJ_01454 1.49e-163 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NEFKHMGJ_01455 4.92e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEFKHMGJ_01456 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEFKHMGJ_01457 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NEFKHMGJ_01458 1.96e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NEFKHMGJ_01459 4.68e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEFKHMGJ_01461 5.18e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_01462 2.56e-70 - - - - - - - -
NEFKHMGJ_01463 8.57e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NEFKHMGJ_01464 2.36e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEFKHMGJ_01465 8.35e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NEFKHMGJ_01466 4.25e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NEFKHMGJ_01467 5.95e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEFKHMGJ_01468 1.14e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NEFKHMGJ_01469 1.47e-90 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NEFKHMGJ_01470 5.66e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NEFKHMGJ_01471 4.18e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEFKHMGJ_01472 1.54e-215 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEFKHMGJ_01473 7.61e-217 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEFKHMGJ_01474 8.53e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NEFKHMGJ_01475 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEFKHMGJ_01476 4.24e-307 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NEFKHMGJ_01477 4.23e-104 - - - FG - - - adenosine 5'-monophosphoramidase activity
NEFKHMGJ_01478 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NEFKHMGJ_01479 5.09e-148 - - - J - - - HAD-hyrolase-like
NEFKHMGJ_01480 2.64e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEFKHMGJ_01481 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEFKHMGJ_01482 1.29e-15 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEFKHMGJ_01483 1.7e-70 - - - - - - - -
NEFKHMGJ_01484 1.17e-163 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEFKHMGJ_01485 8.28e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NEFKHMGJ_01486 8.57e-114 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NEFKHMGJ_01487 2.26e-143 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NEFKHMGJ_01488 1.1e-50 - - - - - - - -
NEFKHMGJ_01489 7.44e-84 - - - S - - - Protein of unknown function (DUF1093)
NEFKHMGJ_01490 3.45e-37 - - - - - - - -
NEFKHMGJ_01491 8.97e-81 - - - - - - - -
NEFKHMGJ_01493 1.08e-143 - - - S - - - Flavodoxin-like fold
NEFKHMGJ_01494 7.04e-121 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_01495 1.3e-238 mocA - - S - - - Oxidoreductase
NEFKHMGJ_01496 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NEFKHMGJ_01497 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEFKHMGJ_01499 0.0 - 2.4.1.9, 3.4.24.40 GH68 M ko:K01406,ko:K20811 ko00500,ko01503,map00500,map01503 ko00000,ko00001,ko01000,ko01002 domain protein
NEFKHMGJ_01501 0.0 - - - - - - - -
NEFKHMGJ_01502 1.34e-296 - - - - - - - -
NEFKHMGJ_01503 9.96e-244 - - - - - - - -
NEFKHMGJ_01504 8.69e-186 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
NEFKHMGJ_01505 8.85e-72 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NEFKHMGJ_01506 2.18e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEFKHMGJ_01507 4.87e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEFKHMGJ_01508 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NEFKHMGJ_01509 2.01e-81 - - - - - - - -
NEFKHMGJ_01510 4.13e-109 - - - S - - - ASCH
NEFKHMGJ_01511 4.01e-44 - - - - - - - -
NEFKHMGJ_01512 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEFKHMGJ_01513 3.88e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEFKHMGJ_01514 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NEFKHMGJ_01515 5.93e-128 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEFKHMGJ_01516 2.27e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEFKHMGJ_01518 5.95e-286 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NEFKHMGJ_01519 5.81e-221 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEFKHMGJ_01520 7.74e-203 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEFKHMGJ_01521 1.91e-152 yceF - - P ko:K05794 - ko00000 membrane
NEFKHMGJ_01522 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEFKHMGJ_01523 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEFKHMGJ_01524 1.85e-59 ylxQ - - J - - - ribosomal protein
NEFKHMGJ_01525 2.02e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NEFKHMGJ_01526 4.49e-278 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEFKHMGJ_01527 3.81e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NEFKHMGJ_01528 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_01529 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEFKHMGJ_01530 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEFKHMGJ_01531 2.89e-291 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NEFKHMGJ_01532 4.82e-182 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NEFKHMGJ_01533 2.05e-177 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEFKHMGJ_01534 4.96e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEFKHMGJ_01535 9.72e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEFKHMGJ_01536 3.28e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEFKHMGJ_01537 9.72e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEFKHMGJ_01538 1.29e-63 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NEFKHMGJ_01539 6.09e-173 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NEFKHMGJ_01540 4.02e-158 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NEFKHMGJ_01541 1.2e-302 yhdG - - E ko:K03294 - ko00000 Amino Acid
NEFKHMGJ_01542 3.12e-177 yejC - - S - - - Protein of unknown function (DUF1003)
NEFKHMGJ_01543 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_01544 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_01545 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NEFKHMGJ_01546 3.45e-49 ynzC - - S - - - UPF0291 protein
NEFKHMGJ_01547 1.08e-35 - - - - - - - -
NEFKHMGJ_01548 1.16e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEFKHMGJ_01549 1.45e-187 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEFKHMGJ_01550 9.14e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEFKHMGJ_01551 6.31e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NEFKHMGJ_01552 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEFKHMGJ_01553 1.02e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEFKHMGJ_01554 2.45e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEFKHMGJ_01555 2.1e-33 - - - - - - - -
NEFKHMGJ_01556 1.12e-69 - - - - - - - -
NEFKHMGJ_01557 3.16e-233 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEFKHMGJ_01558 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NEFKHMGJ_01559 2.68e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEFKHMGJ_01560 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEFKHMGJ_01561 6.51e-196 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_01562 1.48e-221 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01563 1.97e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEFKHMGJ_01564 1.17e-244 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEFKHMGJ_01565 9.22e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEFKHMGJ_01566 1.41e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEFKHMGJ_01567 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEFKHMGJ_01568 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NEFKHMGJ_01569 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
NEFKHMGJ_01570 3.26e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NEFKHMGJ_01571 2.42e-162 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NEFKHMGJ_01572 2.81e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NEFKHMGJ_01573 4.06e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEFKHMGJ_01574 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NEFKHMGJ_01575 2.59e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NEFKHMGJ_01576 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEFKHMGJ_01577 1.38e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEFKHMGJ_01578 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEFKHMGJ_01579 3.8e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEFKHMGJ_01580 4.4e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEFKHMGJ_01581 5.09e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEFKHMGJ_01582 1.23e-153 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
NEFKHMGJ_01583 8.07e-68 - - - - - - - -
NEFKHMGJ_01584 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NEFKHMGJ_01585 1.03e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEFKHMGJ_01586 4.68e-196 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NEFKHMGJ_01587 2.76e-187 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEFKHMGJ_01588 2.87e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEFKHMGJ_01589 6.35e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEFKHMGJ_01590 9.8e-197 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEFKHMGJ_01591 1.29e-87 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEFKHMGJ_01592 8.72e-100 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NEFKHMGJ_01593 4.27e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEFKHMGJ_01594 2.92e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEFKHMGJ_01595 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NEFKHMGJ_01596 1.7e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NEFKHMGJ_01597 1.18e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NEFKHMGJ_01598 1.88e-43 - - - - - - - -
NEFKHMGJ_01599 1.77e-20 - - - - - - - -
NEFKHMGJ_01600 2.31e-298 - - - S - - - Membrane
NEFKHMGJ_01602 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEFKHMGJ_01603 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEFKHMGJ_01604 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEFKHMGJ_01605 5.4e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NEFKHMGJ_01606 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NEFKHMGJ_01607 1.42e-306 ynbB - - P - - - aluminum resistance
NEFKHMGJ_01608 1.97e-230 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEFKHMGJ_01609 2.75e-34 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NEFKHMGJ_01610 6.47e-95 yqhL - - P - - - Rhodanese-like protein
NEFKHMGJ_01611 4.82e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NEFKHMGJ_01612 1.37e-54 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NEFKHMGJ_01613 2.21e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NEFKHMGJ_01614 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEFKHMGJ_01615 0.0 - - - S - - - Bacterial membrane protein YfhO
NEFKHMGJ_01616 1.91e-70 yneR - - S - - - Belongs to the HesB IscA family
NEFKHMGJ_01617 3.39e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NEFKHMGJ_01618 2.79e-234 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEFKHMGJ_01619 3.99e-167 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NEFKHMGJ_01620 6.1e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEFKHMGJ_01621 9.83e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NEFKHMGJ_01622 1.59e-266 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEFKHMGJ_01623 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEFKHMGJ_01624 4.32e-260 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEFKHMGJ_01625 1.44e-90 yodB - - K - - - Transcriptional regulator, HxlR family
NEFKHMGJ_01626 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEFKHMGJ_01627 2.48e-175 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEFKHMGJ_01628 1.45e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NEFKHMGJ_01629 9.37e-230 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEFKHMGJ_01630 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEFKHMGJ_01631 1.01e-157 csrR - - K - - - response regulator
NEFKHMGJ_01632 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEFKHMGJ_01633 3.4e-124 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NEFKHMGJ_01634 2.27e-268 ylbM - - S - - - Belongs to the UPF0348 family
NEFKHMGJ_01635 8.06e-177 yqeM - - Q - - - Methyltransferase
NEFKHMGJ_01636 1.68e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEFKHMGJ_01637 9.21e-142 yqeK - - H - - - Hydrolase, HD family
NEFKHMGJ_01638 1.19e-150 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEFKHMGJ_01639 6.56e-64 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NEFKHMGJ_01640 1.14e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NEFKHMGJ_01641 4.16e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NEFKHMGJ_01642 6.54e-219 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEFKHMGJ_01643 5.53e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEFKHMGJ_01644 8.79e-156 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
NEFKHMGJ_01645 5.4e-225 - - - C - - - Alcohol dehydrogenase GroES-like domain
NEFKHMGJ_01646 4.79e-129 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NEFKHMGJ_01647 1.44e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEFKHMGJ_01648 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NEFKHMGJ_01649 2.6e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEFKHMGJ_01650 1.13e-93 - - - K - - - Transcriptional regulator
NEFKHMGJ_01651 2.07e-296 norB - - EGP ko:K08170 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
NEFKHMGJ_01652 2.81e-174 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
NEFKHMGJ_01653 1.24e-164 - - - S - - - SseB protein N-terminal domain
NEFKHMGJ_01654 3.4e-85 - - - - - - - -
NEFKHMGJ_01655 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEFKHMGJ_01656 2.33e-283 - - - V ko:K07454 - ko00000 regulation of methylation-dependent chromatin silencing
NEFKHMGJ_01657 1.12e-216 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NEFKHMGJ_01658 1.86e-316 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NEFKHMGJ_01659 3.55e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEFKHMGJ_01660 1.15e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEFKHMGJ_01661 1.52e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEFKHMGJ_01662 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEFKHMGJ_01663 1.65e-151 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
NEFKHMGJ_01664 8.57e-248 - - - S - - - Cell surface protein
NEFKHMGJ_01666 2.56e-177 - - - S - - - WxL domain surface cell wall-binding
NEFKHMGJ_01667 0.0 - - - N - - - domain, Protein
NEFKHMGJ_01668 0.0 XK27_00195 - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01669 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NEFKHMGJ_01670 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEFKHMGJ_01672 5.69e-147 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEFKHMGJ_01673 4.38e-72 ytpP - - CO - - - Thioredoxin
NEFKHMGJ_01675 1.11e-154 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEFKHMGJ_01676 3.86e-190 ytmP - - M - - - Choline/ethanolamine kinase
NEFKHMGJ_01677 4.39e-286 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_01678 2.48e-170 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01679 1.14e-96 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NEFKHMGJ_01680 2.79e-77 - - - S - - - YtxH-like protein
NEFKHMGJ_01681 2.5e-203 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEFKHMGJ_01682 1.25e-233 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEFKHMGJ_01683 3.88e-73 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
NEFKHMGJ_01684 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NEFKHMGJ_01685 4.88e-199 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NEFKHMGJ_01686 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEFKHMGJ_01687 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NEFKHMGJ_01689 1.97e-88 - - - - - - - -
NEFKHMGJ_01690 5.54e-30 - - - - - - - -
NEFKHMGJ_01691 7.68e-225 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
NEFKHMGJ_01692 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NEFKHMGJ_01693 9.38e-158 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEFKHMGJ_01694 1.8e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEFKHMGJ_01695 1.34e-175 yhfI - - S - - - Metallo-beta-lactamase superfamily
NEFKHMGJ_01696 9.97e-119 - - - S - - - Antibiotic biosynthesis monooxygenase
NEFKHMGJ_01697 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NEFKHMGJ_01698 5.63e-178 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_01699 3.07e-156 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
NEFKHMGJ_01700 2.53e-264 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
NEFKHMGJ_01701 1.09e-139 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEFKHMGJ_01702 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
NEFKHMGJ_01703 9.59e-101 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NEFKHMGJ_01704 2.93e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NEFKHMGJ_01705 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NEFKHMGJ_01706 2.36e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEFKHMGJ_01707 1.07e-238 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NEFKHMGJ_01708 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEFKHMGJ_01709 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEFKHMGJ_01710 3.56e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEFKHMGJ_01711 5.52e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEFKHMGJ_01712 1.9e-171 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NEFKHMGJ_01713 1.74e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEFKHMGJ_01714 6.02e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEFKHMGJ_01715 9.11e-134 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NEFKHMGJ_01717 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEFKHMGJ_01718 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEFKHMGJ_01719 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NEFKHMGJ_01720 6.69e-39 - - - - - - - -
NEFKHMGJ_01721 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NEFKHMGJ_01722 2.87e-62 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NEFKHMGJ_01723 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEFKHMGJ_01724 1.88e-307 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
NEFKHMGJ_01725 4.36e-264 yueF - - S - - - AI-2E family transporter
NEFKHMGJ_01726 1.96e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01727 1.16e-124 - - - - - - - -
NEFKHMGJ_01728 4.26e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NEFKHMGJ_01729 4.78e-179 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NEFKHMGJ_01730 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01731 6.41e-84 - - - - - - - -
NEFKHMGJ_01732 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEFKHMGJ_01733 3.38e-104 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NEFKHMGJ_01734 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEFKHMGJ_01735 1.76e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NEFKHMGJ_01736 1.64e-269 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NEFKHMGJ_01737 9.92e-266 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NEFKHMGJ_01738 1.71e-64 - - - - - - - -
NEFKHMGJ_01739 1.41e-206 - - - G - - - Xylose isomerase domain protein TIM barrel
NEFKHMGJ_01740 1.49e-132 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
NEFKHMGJ_01741 1.03e-204 - - - G - - - Aldose 1-epimerase
NEFKHMGJ_01742 6.51e-269 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEFKHMGJ_01743 6.88e-129 - - - S - - - ECF transporter, substrate-specific component
NEFKHMGJ_01745 1.63e-104 - - - K - - - FR47-like protein
NEFKHMGJ_01746 1.78e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NEFKHMGJ_01747 1.59e-165 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01748 1.77e-175 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEFKHMGJ_01749 3.78e-225 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_01750 1.6e-93 - - - - - - - -
NEFKHMGJ_01751 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEFKHMGJ_01752 1.18e-274 - - - V - - - Beta-lactamase
NEFKHMGJ_01753 4.16e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEFKHMGJ_01754 3.74e-284 - - - V - - - Beta-lactamase
NEFKHMGJ_01755 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEFKHMGJ_01756 2.79e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NEFKHMGJ_01757 2.49e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEFKHMGJ_01758 5.58e-178 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEFKHMGJ_01759 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
NEFKHMGJ_01760 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
NEFKHMGJ_01761 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01763 9.12e-199 - - - S - - - Calcineurin-like phosphoesterase
NEFKHMGJ_01764 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NEFKHMGJ_01765 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01766 2.43e-87 - - - - - - - -
NEFKHMGJ_01767 8.48e-23 - - - S - - - function, without similarity to other proteins
NEFKHMGJ_01768 0.0 - - - G - - - MFS/sugar transport protein
NEFKHMGJ_01769 1.12e-293 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NEFKHMGJ_01770 3.89e-75 - - - - - - - -
NEFKHMGJ_01771 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NEFKHMGJ_01772 3.18e-34 - - - S - - - Virus attachment protein p12 family
NEFKHMGJ_01773 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NEFKHMGJ_01774 2.5e-106 feoA - - P ko:K04758 - ko00000,ko02000 FeoA
NEFKHMGJ_01775 2.11e-171 - - - E - - - lipolytic protein G-D-S-L family
NEFKHMGJ_01776 2.03e-106 - - - E - - - AAA domain
NEFKHMGJ_01779 2.62e-152 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NEFKHMGJ_01780 1.95e-118 - - - S - - - MucBP domain
NEFKHMGJ_01781 5.24e-113 - - - - - - - -
NEFKHMGJ_01784 1.13e-93 - - - S - - - COG NOG38524 non supervised orthologous group
NEFKHMGJ_01787 1.45e-46 - - - - - - - -
NEFKHMGJ_01788 1.03e-282 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEFKHMGJ_01789 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01790 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_01791 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NEFKHMGJ_01793 1.97e-168 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NEFKHMGJ_01794 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NEFKHMGJ_01795 1.96e-126 - - - - - - - -
NEFKHMGJ_01796 2.79e-124 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEFKHMGJ_01797 2.24e-239 - - - S - - - Bacterial protein of unknown function (DUF916)
NEFKHMGJ_01798 8.57e-134 - - - - - - - -
NEFKHMGJ_01799 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEFKHMGJ_01800 1.11e-203 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEFKHMGJ_01801 8.47e-200 - - - I - - - alpha/beta hydrolase fold
NEFKHMGJ_01802 8.21e-85 - - - - - - - -
NEFKHMGJ_01803 1.37e-90 - - - - - - - -
NEFKHMGJ_01804 4.37e-206 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NEFKHMGJ_01805 6.87e-162 citR - - K - - - FCD
NEFKHMGJ_01806 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
NEFKHMGJ_01807 4.83e-131 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NEFKHMGJ_01808 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NEFKHMGJ_01809 7.15e-199 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NEFKHMGJ_01810 1.9e-62 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NEFKHMGJ_01811 2.31e-232 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NEFKHMGJ_01812 4.63e-07 - - - - - - - -
NEFKHMGJ_01813 4.58e-250 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
NEFKHMGJ_01814 7.15e-58 oadG - - I - - - Biotin-requiring enzyme
NEFKHMGJ_01815 7.81e-67 - - - - - - - -
NEFKHMGJ_01816 2.88e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
NEFKHMGJ_01817 1.04e-54 - - - - - - - -
NEFKHMGJ_01818 9.05e-127 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NEFKHMGJ_01819 8.17e-114 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01820 3.69e-135 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEFKHMGJ_01821 1.32e-74 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NEFKHMGJ_01822 9.28e-110 ORF00048 - - - - - - -
NEFKHMGJ_01823 5e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NEFKHMGJ_01824 1.4e-207 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_01825 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NEFKHMGJ_01826 6.65e-145 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NEFKHMGJ_01827 0.0 ypiB - - EGP - - - Major Facilitator
NEFKHMGJ_01828 2.1e-163 - - - S ko:K07090 - ko00000 membrane transporter protein
NEFKHMGJ_01829 5.06e-236 - - - K - - - Helix-turn-helix domain
NEFKHMGJ_01830 1.6e-188 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NEFKHMGJ_01831 3.14e-116 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NEFKHMGJ_01832 9.82e-200 - - - S - - - Alpha beta hydrolase
NEFKHMGJ_01833 5.73e-82 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NEFKHMGJ_01834 1.28e-165 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_01836 2.33e-206 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NEFKHMGJ_01837 5.84e-252 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NEFKHMGJ_01838 6.1e-64 - - - - - - - -
NEFKHMGJ_01839 3.48e-219 - - - P ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
NEFKHMGJ_01840 4.54e-214 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_01841 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEFKHMGJ_01842 1.3e-49 - - - - - - - -
NEFKHMGJ_01843 0.0 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_01844 0.0 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
NEFKHMGJ_01845 9.28e-89 - - - S - - - Iron-sulphur cluster biosynthesis
NEFKHMGJ_01846 1.84e-169 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
NEFKHMGJ_01847 1.28e-156 zmp3 - - O - - - Zinc-dependent metalloprotease
NEFKHMGJ_01848 2.21e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NEFKHMGJ_01850 0.0 - - - M - - - LysM domain
NEFKHMGJ_01852 3.3e-64 lciIC - - K - - - Helix-turn-helix domain
NEFKHMGJ_01853 1.13e-45 - - - L - - - Plasmid pRiA4b ORF-3-like protein
NEFKHMGJ_01854 2.46e-33 - - - L - - - Transposase DDE domain group 1
NEFKHMGJ_01857 1.31e-38 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEFKHMGJ_01858 1.79e-148 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
NEFKHMGJ_01859 7.2e-104 - - - L - - - Restriction endonuclease EcoRV
NEFKHMGJ_01860 2.7e-63 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NEFKHMGJ_01861 5.8e-111 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 DNA methylase
NEFKHMGJ_01862 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEFKHMGJ_01863 3.82e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NEFKHMGJ_01864 2.72e-69 - - - - - - - -
NEFKHMGJ_01865 2.59e-55 - - - - - - - -
NEFKHMGJ_01866 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEFKHMGJ_01867 6.86e-108 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NEFKHMGJ_01868 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEFKHMGJ_01869 2.13e-36 - - - - - - - -
NEFKHMGJ_01870 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NEFKHMGJ_01871 3.98e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEFKHMGJ_01872 7.8e-107 yjhE - - S - - - Phage tail protein
NEFKHMGJ_01873 6.51e-305 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEFKHMGJ_01874 1.77e-235 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NEFKHMGJ_01875 1.64e-164 gpm2 - - G - - - Phosphoglycerate mutase family
NEFKHMGJ_01876 1.02e-219 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NEFKHMGJ_01877 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEFKHMGJ_01878 3.26e-175 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01879 0.0 - - - E - - - Amino Acid
NEFKHMGJ_01880 4.57e-212 - - - I - - - Diacylglycerol kinase catalytic domain
NEFKHMGJ_01881 1.46e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEFKHMGJ_01882 2.68e-140 nodB3 - - G - - - Polysaccharide deacetylase
NEFKHMGJ_01883 0.0 - - - M - - - Sulfatase
NEFKHMGJ_01884 1.7e-221 - - - S - - - EpsG family
NEFKHMGJ_01885 1.13e-107 - - - D - - - Capsular exopolysaccharide family
NEFKHMGJ_01886 1.45e-126 ywqC - - M ko:K16554 ko05111,map05111 ko00000,ko00001,ko02000 capsule polysaccharide biosynthetic process
NEFKHMGJ_01887 6.29e-314 - - - S - - - polysaccharide biosynthetic process
NEFKHMGJ_01888 2.61e-252 - - - M - - - Glycosyl transferases group 1
NEFKHMGJ_01889 1.62e-152 - - - M - - - Glycosyltransferase like family 2
NEFKHMGJ_01890 2.18e-277 - - - S - - - Bacterial membrane protein, YfhO
NEFKHMGJ_01891 0.0 - - - M - - - Glycosyl hydrolases family 25
NEFKHMGJ_01892 7.03e-225 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
NEFKHMGJ_01893 3.19e-142 - - - M - - - Acyltransferase family
NEFKHMGJ_01894 8.66e-202 ykoT - - M - - - Glycosyl transferase family 2
NEFKHMGJ_01895 1.34e-255 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEFKHMGJ_01896 2.25e-107 - - - - - - - -
NEFKHMGJ_01897 0.0 cps2E - - M - - - Bacterial sugar transferase
NEFKHMGJ_01898 5.41e-171 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NEFKHMGJ_01899 1.56e-145 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NEFKHMGJ_01900 1.88e-224 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NEFKHMGJ_01901 7.92e-142 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01902 1.18e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_01903 1.44e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEFKHMGJ_01905 8.66e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_01906 1.13e-220 - - - - - - - -
NEFKHMGJ_01907 0.000417 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NEFKHMGJ_01908 5.53e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NEFKHMGJ_01909 1.1e-13 - - - - - - - -
NEFKHMGJ_01910 1.79e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NEFKHMGJ_01911 1.36e-87 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_01912 2.33e-200 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NEFKHMGJ_01913 2.28e-309 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEFKHMGJ_01914 3.15e-208 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEFKHMGJ_01915 1.38e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEFKHMGJ_01916 2.2e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEFKHMGJ_01917 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEFKHMGJ_01918 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEFKHMGJ_01919 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEFKHMGJ_01920 8.67e-258 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NEFKHMGJ_01921 1.51e-254 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEFKHMGJ_01922 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEFKHMGJ_01923 1.02e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NEFKHMGJ_01924 1.23e-171 - - - M - - - Sortase family
NEFKHMGJ_01925 2.06e-183 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEFKHMGJ_01926 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
NEFKHMGJ_01927 3.92e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
NEFKHMGJ_01928 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
NEFKHMGJ_01929 5.46e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEFKHMGJ_01930 7.73e-201 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEFKHMGJ_01931 7.15e-95 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NEFKHMGJ_01932 3.44e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEFKHMGJ_01933 6.87e-258 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEFKHMGJ_01934 3.12e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NEFKHMGJ_01935 1.25e-207 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEFKHMGJ_01936 8.1e-80 - - - S - - - SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
NEFKHMGJ_01937 1.52e-09 - - - M - - - Glycosyl transferase 4-like
NEFKHMGJ_01939 8.15e-90 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
NEFKHMGJ_01940 5.55e-26 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NEFKHMGJ_01941 1.47e-44 - - - M - - - Glycosyl transferases group 1
NEFKHMGJ_01942 4.43e-46 - - - S - - - Glycosyl transferase family 2
NEFKHMGJ_01943 1.43e-106 cps2J - - S - - - Polysaccharide biosynthesis protein
NEFKHMGJ_01944 2.51e-144 ywqD - - D - - - Capsular exopolysaccharide family
NEFKHMGJ_01945 6.98e-148 epsB - - M - - - biosynthesis protein
NEFKHMGJ_01946 1.23e-169 - - - E - - - lipolytic protein G-D-S-L family
NEFKHMGJ_01947 5.97e-106 ccl - - S - - - QueT transporter
NEFKHMGJ_01948 6.57e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEFKHMGJ_01949 2.98e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NEFKHMGJ_01950 3.39e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEFKHMGJ_01951 2.94e-149 gpm5 - - G - - - Phosphoglycerate mutase family
NEFKHMGJ_01952 2.22e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEFKHMGJ_01953 2.89e-250 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEFKHMGJ_01954 3.36e-224 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEFKHMGJ_01955 1.15e-207 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEFKHMGJ_01956 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEFKHMGJ_01957 0.0 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_01958 5.82e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEFKHMGJ_01959 1.06e-167 lutC - - S ko:K00782 - ko00000 LUD domain
NEFKHMGJ_01960 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NEFKHMGJ_01961 9.83e-190 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NEFKHMGJ_01962 1.54e-130 - - - - - - - -
NEFKHMGJ_01963 6.5e-71 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEFKHMGJ_01964 3.1e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEFKHMGJ_01965 2.25e-91 - - - S - - - Domain of unknown function (DUF3284)
NEFKHMGJ_01966 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEFKHMGJ_01967 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEFKHMGJ_01968 1.18e-170 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NEFKHMGJ_01969 5.85e-171 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NEFKHMGJ_01970 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
NEFKHMGJ_01971 2.01e-141 - - - - - - - -
NEFKHMGJ_01972 1.38e-130 - - - S - - - WxL domain surface cell wall-binding
NEFKHMGJ_01973 1.38e-185 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_01974 0.0 - - - G - - - Phosphodiester glycosidase
NEFKHMGJ_01976 0.0 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
NEFKHMGJ_01977 1.41e-263 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
NEFKHMGJ_01978 4.88e-283 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
NEFKHMGJ_01979 1.27e-164 - - - - - - - -
NEFKHMGJ_01980 0.0 - - - S - - - Protein of unknown function (DUF1524)
NEFKHMGJ_01981 8.49e-52 - - - V - - - Type I restriction modification DNA specificity domain
NEFKHMGJ_01982 1.35e-211 - - - L - - - Belongs to the 'phage' integrase family
NEFKHMGJ_01983 1.36e-88 - - - V - - - Type I restriction modification DNA specificity domain
NEFKHMGJ_01984 2.83e-267 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NEFKHMGJ_01985 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NEFKHMGJ_01986 2.87e-270 - - - - - - - -
NEFKHMGJ_01987 0.0 pip - - V ko:K01421 - ko00000 domain protein
NEFKHMGJ_01988 1.88e-86 pip - - V ko:K01421 - ko00000 domain protein
NEFKHMGJ_01989 8.94e-88 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_01990 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_01991 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEFKHMGJ_01992 6.55e-227 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NEFKHMGJ_01993 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NEFKHMGJ_01995 7.51e-204 - - - GM - - - NmrA-like family
NEFKHMGJ_01996 6.84e-298 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEFKHMGJ_01997 1.02e-185 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NEFKHMGJ_01998 6.61e-189 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEFKHMGJ_01999 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NEFKHMGJ_02000 4.77e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEFKHMGJ_02001 9.15e-90 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEFKHMGJ_02002 4.91e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEFKHMGJ_02003 2.03e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NEFKHMGJ_02004 3.44e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NEFKHMGJ_02005 6.47e-219 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NEFKHMGJ_02006 5.61e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEFKHMGJ_02007 5.82e-223 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEFKHMGJ_02008 4.21e-100 - - - K - - - Winged helix DNA-binding domain
NEFKHMGJ_02009 7.93e-94 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NEFKHMGJ_02010 7.01e-244 - - - I - - - carboxylic ester hydrolase activity
NEFKHMGJ_02011 2.02e-288 - - - C - - - Iron-containing alcohol dehydrogenase
NEFKHMGJ_02012 6.3e-82 - - - P - - - Rhodanese-like domain
NEFKHMGJ_02013 9.96e-109 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEFKHMGJ_02014 5.55e-101 - - - T - - - diguanylate cyclase activity
NEFKHMGJ_02015 8.09e-256 - - - S - - - Bacterial cellulose synthase subunit
NEFKHMGJ_02016 2.24e-228 ydaM - - M - - - Glycosyl transferase family group 2
NEFKHMGJ_02017 2.65e-97 - - - S - - - Protein conserved in bacteria
NEFKHMGJ_02018 4.47e-79 - - - - - - - -
NEFKHMGJ_02019 9.3e-100 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NEFKHMGJ_02020 2.7e-67 - - - T - - - diguanylate cyclase
NEFKHMGJ_02021 1.12e-213 nox - - C - - - NADH oxidase
NEFKHMGJ_02022 2.87e-92 - - - T - - - Putative diguanylate phosphodiesterase
NEFKHMGJ_02023 3.31e-89 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
NEFKHMGJ_02024 3.25e-13 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEFKHMGJ_02025 6.75e-112 - - - S - - - Putative esterase
NEFKHMGJ_02026 6.05e-74 - - - S - - - Putative esterase
NEFKHMGJ_02027 1.42e-233 - - - - - - - -
NEFKHMGJ_02028 3.09e-133 - - - K - - - Transcriptional regulator, MarR family
NEFKHMGJ_02029 1.39e-110 - - - F - - - NUDIX domain
NEFKHMGJ_02030 1.89e-220 - - - U - - - Major Facilitator Superfamily
NEFKHMGJ_02031 1.42e-49 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEFKHMGJ_02032 1.15e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEFKHMGJ_02033 2.82e-40 - - - - - - - -
NEFKHMGJ_02034 3.53e-188 - - - S - - - zinc-ribbon domain
NEFKHMGJ_02035 3.38e-252 pbpX - - V - - - Beta-lactamase
NEFKHMGJ_02036 1.77e-239 ydbI - - K - - - AI-2E family transporter
NEFKHMGJ_02037 1.19e-163 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEFKHMGJ_02038 2e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
NEFKHMGJ_02039 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEFKHMGJ_02040 1.17e-217 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEFKHMGJ_02041 1.23e-190 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEFKHMGJ_02042 1.85e-284 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NEFKHMGJ_02043 1.23e-170 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
NEFKHMGJ_02044 8.35e-93 usp1 - - T - - - Universal stress protein family
NEFKHMGJ_02045 9.92e-317 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NEFKHMGJ_02046 3.25e-195 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEFKHMGJ_02047 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NEFKHMGJ_02048 4.79e-292 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NEFKHMGJ_02049 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEFKHMGJ_02050 7.02e-286 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
NEFKHMGJ_02051 1.92e-88 - - - - - - - -
NEFKHMGJ_02052 5.76e-212 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NEFKHMGJ_02053 1.81e-227 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEFKHMGJ_02054 7.71e-276 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEFKHMGJ_02055 3.93e-32 - - - E - - - lactoylglutathione lyase activity
NEFKHMGJ_02056 9.23e-155 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
NEFKHMGJ_02057 1.34e-188 - - - S - - - Alpha/beta hydrolase family
NEFKHMGJ_02058 5.73e-130 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_02059 7.57e-226 - - - V ko:K01421 - ko00000 domain protein
NEFKHMGJ_02060 4.41e-220 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEFKHMGJ_02061 4.01e-307 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_02062 1.1e-71 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_02063 9.5e-221 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_02064 2.56e-42 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02065 2.87e-87 - - - S - - - Uncharacterised protein family UPF0047
NEFKHMGJ_02066 3.08e-71 - - - M - - - SIS domain
NEFKHMGJ_02067 1.86e-107 - 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NEFKHMGJ_02068 4.42e-60 - 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 arabinose-5-phosphate isomerase activity
NEFKHMGJ_02069 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEFKHMGJ_02070 3.78e-15 - - - - - - - -
NEFKHMGJ_02071 5.92e-261 - - - S - - - Calcineurin-like phosphoesterase
NEFKHMGJ_02072 1.24e-205 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEFKHMGJ_02073 1.33e-225 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEFKHMGJ_02074 4.52e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEFKHMGJ_02075 1.72e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_02076 1.45e-280 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEFKHMGJ_02077 3.94e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEFKHMGJ_02078 5.96e-205 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_02079 1.98e-148 - - - I - - - ABC-2 family transporter protein
NEFKHMGJ_02080 2.3e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
NEFKHMGJ_02081 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEFKHMGJ_02082 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEFKHMGJ_02083 9.88e-205 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEFKHMGJ_02084 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEFKHMGJ_02085 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEFKHMGJ_02086 3.68e-97 - - - S - - - NusG domain II
NEFKHMGJ_02087 3.34e-232 - - - M - - - Peptidoglycan-binding domain 1 protein
NEFKHMGJ_02088 2.29e-48 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_02089 3.49e-148 - - - S - - - CRISPR-associated protein (Cas_Csn2)
NEFKHMGJ_02090 8.37e-66 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEFKHMGJ_02091 7.04e-216 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEFKHMGJ_02092 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NEFKHMGJ_02093 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEFKHMGJ_02094 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEFKHMGJ_02095 2.91e-232 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NEFKHMGJ_02096 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NEFKHMGJ_02097 3.2e-301 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
NEFKHMGJ_02098 1.27e-227 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NEFKHMGJ_02099 1.18e-50 - - - - - - - -
NEFKHMGJ_02100 5.18e-114 - - - - - - - -
NEFKHMGJ_02101 1.57e-34 - - - - - - - -
NEFKHMGJ_02102 2.32e-206 - - - EG - - - EamA-like transporter family
NEFKHMGJ_02103 2.08e-145 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEFKHMGJ_02104 1.94e-100 usp5 - - T - - - universal stress protein
NEFKHMGJ_02105 8.34e-86 - - - K - - - Helix-turn-helix domain
NEFKHMGJ_02106 1.29e-186 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEFKHMGJ_02107 5.06e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
NEFKHMGJ_02108 3.64e-83 - - - - - - - -
NEFKHMGJ_02109 2.46e-114 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NEFKHMGJ_02111 5.22e-132 - - - Q - - - methyltransferase
NEFKHMGJ_02112 2.41e-145 - - - T - - - Sh3 type 3 domain protein
NEFKHMGJ_02113 1.78e-147 - - - F - - - glutamine amidotransferase
NEFKHMGJ_02114 1.5e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NEFKHMGJ_02115 0.0 yhdP - - S - - - Transporter associated domain
NEFKHMGJ_02116 2.69e-185 - - - S - - - Alpha beta hydrolase
NEFKHMGJ_02117 9.69e-254 - - - I - - - Acyltransferase
NEFKHMGJ_02118 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEFKHMGJ_02119 1.31e-108 - - - S - - - Domain of unknown function (DUF4811)
NEFKHMGJ_02120 5.61e-121 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
NEFKHMGJ_02121 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEFKHMGJ_02122 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEFKHMGJ_02123 0.0 ydaO - - E - - - amino acid
NEFKHMGJ_02124 7.56e-75 - - - S - - - Domain of unknown function (DUF1827)
NEFKHMGJ_02125 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_02126 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEFKHMGJ_02127 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEFKHMGJ_02128 4.3e-143 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_02129 4.11e-251 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEFKHMGJ_02130 2.1e-246 - - - - - - - -
NEFKHMGJ_02131 5.93e-204 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_02132 7.06e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEFKHMGJ_02133 7.76e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEFKHMGJ_02134 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NEFKHMGJ_02135 1.98e-65 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02136 4.36e-240 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEFKHMGJ_02137 1.06e-127 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NEFKHMGJ_02138 5.42e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NEFKHMGJ_02139 4.07e-135 - - - - - - - -
NEFKHMGJ_02140 4.02e-116 - - - T - - - ECF transporter, substrate-specific component
NEFKHMGJ_02141 8.71e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NEFKHMGJ_02142 9.48e-186 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NEFKHMGJ_02143 9.39e-196 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEFKHMGJ_02144 2.27e-75 yabA - - L - - - Involved in initiation control of chromosome replication
NEFKHMGJ_02145 1.13e-223 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEFKHMGJ_02146 2.31e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
NEFKHMGJ_02147 3.17e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEFKHMGJ_02148 1.35e-51 - - - S - - - Protein of unknown function (DUF2508)
NEFKHMGJ_02149 2.17e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEFKHMGJ_02150 2.29e-50 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEFKHMGJ_02151 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEFKHMGJ_02152 2.44e-111 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEFKHMGJ_02153 5.69e-65 - - - - - - - -
NEFKHMGJ_02154 8.19e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NEFKHMGJ_02155 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEFKHMGJ_02156 2.83e-90 - - - - - - - -
NEFKHMGJ_02157 1e-219 ccpB - - K - - - lacI family
NEFKHMGJ_02158 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NEFKHMGJ_02159 5.88e-202 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEFKHMGJ_02160 3.91e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEFKHMGJ_02161 6.19e-109 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEFKHMGJ_02162 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_02163 1.04e-287 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEFKHMGJ_02164 1.51e-195 - - - K - - - acetyltransferase
NEFKHMGJ_02165 2.31e-115 - - - - - - - -
NEFKHMGJ_02166 1.03e-281 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NEFKHMGJ_02167 5e-39 - - - - - - - -
NEFKHMGJ_02168 3.26e-265 - - - - - - - -
NEFKHMGJ_02169 1.34e-36 - - - - - - - -
NEFKHMGJ_02170 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEFKHMGJ_02171 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NEFKHMGJ_02172 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NEFKHMGJ_02173 2.79e-125 yqaB - - S - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_02174 1.33e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEFKHMGJ_02175 1.97e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEFKHMGJ_02176 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
NEFKHMGJ_02177 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NEFKHMGJ_02178 6.59e-118 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
NEFKHMGJ_02179 4.97e-114 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
NEFKHMGJ_02180 2.89e-82 - - - S - - - Domain of unknown function (DUF4430)
NEFKHMGJ_02181 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
NEFKHMGJ_02182 6.51e-103 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
NEFKHMGJ_02183 7.82e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEFKHMGJ_02184 8e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NEFKHMGJ_02185 2.53e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEFKHMGJ_02186 3.75e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEFKHMGJ_02187 1.26e-217 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEFKHMGJ_02188 3.56e-209 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NEFKHMGJ_02189 1.54e-247 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEFKHMGJ_02190 5.17e-293 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEFKHMGJ_02191 7.5e-190 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
NEFKHMGJ_02192 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEFKHMGJ_02193 1.94e-104 - - - S - - - NusG domain II
NEFKHMGJ_02194 7.23e-128 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NEFKHMGJ_02195 2.7e-231 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEFKHMGJ_02196 2.93e-42 - - - - - - - -
NEFKHMGJ_02197 3.29e-50 - - - - - - - -
NEFKHMGJ_02199 1.39e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_02200 6.32e-277 - - - - - - - -
NEFKHMGJ_02201 1.04e-249 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEFKHMGJ_02202 3.82e-157 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
NEFKHMGJ_02203 6.29e-250 XK27_00915 - - C - - - Luciferase-like monooxygenase
NEFKHMGJ_02204 1.45e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NEFKHMGJ_02205 1.06e-184 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEFKHMGJ_02206 2.79e-97 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEFKHMGJ_02207 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEFKHMGJ_02208 3.44e-185 - - - K - - - sequence-specific DNA binding
NEFKHMGJ_02209 2.49e-311 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NEFKHMGJ_02210 1.22e-125 - - - - - - - -
NEFKHMGJ_02212 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEFKHMGJ_02213 4.24e-183 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NEFKHMGJ_02214 3.93e-226 - - - S - - - Membrane
NEFKHMGJ_02215 3.54e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEFKHMGJ_02216 0.0 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_02217 2.42e-298 inlJ - - M - - - MucBP domain
NEFKHMGJ_02218 6.42e-88 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEFKHMGJ_02219 9.79e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02220 1.12e-138 - - - K - - - sequence-specific DNA binding
NEFKHMGJ_02221 1.06e-258 yacL - - S - - - domain protein
NEFKHMGJ_02222 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEFKHMGJ_02223 2.6e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
NEFKHMGJ_02224 1.17e-65 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NEFKHMGJ_02225 2.61e-98 - - - L - - - Resolvase, N-terminal
NEFKHMGJ_02226 5.17e-293 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
NEFKHMGJ_02228 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NEFKHMGJ_02229 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEFKHMGJ_02230 1.05e-251 - - - - - - - -
NEFKHMGJ_02231 7.65e-272 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEFKHMGJ_02232 1.21e-210 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_02233 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEFKHMGJ_02234 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
NEFKHMGJ_02235 2.36e-119 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
NEFKHMGJ_02236 9.8e-158 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEFKHMGJ_02237 1.56e-256 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
NEFKHMGJ_02238 5.45e-61 - - - - - - - -
NEFKHMGJ_02239 5.21e-229 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEFKHMGJ_02240 5.54e-23 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEFKHMGJ_02241 9.49e-26 - - - S - - - CsbD-like
NEFKHMGJ_02242 1.01e-190 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEFKHMGJ_02243 3.49e-242 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
NEFKHMGJ_02244 2.35e-145 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
NEFKHMGJ_02245 2.15e-215 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
NEFKHMGJ_02246 1.01e-119 - - - KT ko:K02647 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NEFKHMGJ_02248 2.13e-44 - - - - - - - -
NEFKHMGJ_02249 6.67e-46 - - - - - - - -
NEFKHMGJ_02250 1.41e-285 - - - EGP - - - Transmembrane secretion effector
NEFKHMGJ_02251 1.37e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEFKHMGJ_02252 4.13e-191 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEFKHMGJ_02254 1.09e-117 - - - - - - - -
NEFKHMGJ_02255 3.66e-36 - - - V - - - MacB-like periplasmic core domain
NEFKHMGJ_02256 1.16e-69 salX - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02258 6.84e-174 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEFKHMGJ_02259 0.0 - - - M - - - Cna protein B-type domain
NEFKHMGJ_02260 0.0 - - - M - - - domain protein
NEFKHMGJ_02261 0.0 - - - M - - - domain protein
NEFKHMGJ_02262 1.81e-132 - - - - - - - -
NEFKHMGJ_02263 2.19e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_02264 7.18e-281 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NEFKHMGJ_02265 2.42e-263 - - - S - - - Protein of unknown function (DUF2974)
NEFKHMGJ_02266 1.49e-123 - - - K - - - Helix-turn-helix XRE-family like proteins
NEFKHMGJ_02267 5.62e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NEFKHMGJ_02268 6.8e-177 - - - - - - - -
NEFKHMGJ_02269 2.36e-171 - - - - - - - -
NEFKHMGJ_02270 2.47e-58 - - - S - - - Enterocin A Immunity
NEFKHMGJ_02271 2.53e-236 tas - - C - - - Aldo/keto reductase family
NEFKHMGJ_02272 9e-195 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NEFKHMGJ_02273 1.89e-117 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NEFKHMGJ_02274 0.0 - - - S - - - Putative threonine/serine exporter
NEFKHMGJ_02275 1.15e-75 - - - - - - - -
NEFKHMGJ_02276 7.14e-297 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NEFKHMGJ_02277 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEFKHMGJ_02279 1.5e-103 comD 2.7.13.3 - T ko:K07706,ko:K12294 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEFKHMGJ_02280 4.33e-168 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEFKHMGJ_02283 2.63e-59 - - - S - - - Enterocin A Immunity
NEFKHMGJ_02284 6.51e-30 - - - - - - - -
NEFKHMGJ_02288 2.25e-174 - - - S - - - CAAX protease self-immunity
NEFKHMGJ_02289 8.21e-92 - - - K - - - Transcriptional regulator
NEFKHMGJ_02290 1.3e-314 norB - - EGP ko:K08170 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
NEFKHMGJ_02291 1.05e-70 - - - - - - - -
NEFKHMGJ_02292 4.57e-71 - - - S - - - Enterocin A Immunity
NEFKHMGJ_02293 7.17e-232 ydhF - - S - - - Aldo keto reductase
NEFKHMGJ_02294 1.49e-167 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEFKHMGJ_02295 2.2e-272 yqiG - - C - - - Oxidoreductase
NEFKHMGJ_02296 2.54e-30 - - - S - - - Short C-terminal domain
NEFKHMGJ_02297 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEFKHMGJ_02298 7.37e-169 - - - - - - - -
NEFKHMGJ_02299 2.61e-25 - - - - - - - -
NEFKHMGJ_02300 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEFKHMGJ_02301 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEFKHMGJ_02302 4.42e-84 - - - - - - - -
NEFKHMGJ_02303 1.61e-288 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_02304 0.0 sufI - - Q - - - Multicopper oxidase
NEFKHMGJ_02305 2.5e-34 - - - - - - - -
NEFKHMGJ_02306 5.65e-143 - - - P - - - Cation efflux family
NEFKHMGJ_02307 1.68e-67 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NEFKHMGJ_02308 1.55e-224 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEFKHMGJ_02309 9.44e-186 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEFKHMGJ_02310 4.8e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEFKHMGJ_02311 8.32e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEFKHMGJ_02312 2.35e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEFKHMGJ_02313 1.64e-151 - - - GM - - - NmrA-like family
NEFKHMGJ_02314 8.81e-112 - - - - - - - -
NEFKHMGJ_02315 1.64e-208 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEFKHMGJ_02316 2.99e-27 - - - - - - - -
NEFKHMGJ_02318 1.35e-69 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEFKHMGJ_02319 2.53e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEFKHMGJ_02320 0.0 - - - G ko:K03292,ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
NEFKHMGJ_02321 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase concanavalin-like domain
NEFKHMGJ_02322 3.74e-217 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
NEFKHMGJ_02323 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
NEFKHMGJ_02324 2.41e-299 - - - I - - - Acyltransferase family
NEFKHMGJ_02325 2.36e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_02326 3.4e-189 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEFKHMGJ_02327 1.29e-157 - - - S - - - B3/4 domain
NEFKHMGJ_02328 2.13e-18 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEFKHMGJ_02330 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEFKHMGJ_02331 0.0 - - - V - - - ATPases associated with a variety of cellular activities
NEFKHMGJ_02332 2.52e-264 - - - EGP - - - Transmembrane secretion effector
NEFKHMGJ_02333 3.01e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEFKHMGJ_02334 4.23e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEFKHMGJ_02335 4.31e-136 - - - K - - - Bacterial regulatory proteins, tetR family
NEFKHMGJ_02336 1.06e-237 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEFKHMGJ_02337 4.28e-163 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_02338 1.28e-45 - - - - - - - -
NEFKHMGJ_02339 7.1e-175 tipA - - K - - - TipAS antibiotic-recognition domain
NEFKHMGJ_02341 3.99e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEFKHMGJ_02342 5.43e-185 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEFKHMGJ_02343 5.02e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEFKHMGJ_02344 7.77e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEFKHMGJ_02345 3.15e-153 - - - - - - - -
NEFKHMGJ_02346 2.94e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEFKHMGJ_02347 1.8e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEFKHMGJ_02348 3.14e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEFKHMGJ_02349 3.78e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEFKHMGJ_02350 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NEFKHMGJ_02351 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEFKHMGJ_02352 3.86e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEFKHMGJ_02353 1.63e-297 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEFKHMGJ_02354 1.42e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEFKHMGJ_02355 1.83e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NEFKHMGJ_02356 8.15e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEFKHMGJ_02357 5.63e-77 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEFKHMGJ_02358 3.7e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEFKHMGJ_02359 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEFKHMGJ_02360 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEFKHMGJ_02361 1.67e-66 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEFKHMGJ_02362 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEFKHMGJ_02363 9.86e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEFKHMGJ_02364 4.53e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NEFKHMGJ_02365 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEFKHMGJ_02366 2.92e-153 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEFKHMGJ_02367 4.5e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEFKHMGJ_02368 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEFKHMGJ_02369 2.07e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEFKHMGJ_02370 5.07e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEFKHMGJ_02371 3.43e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NEFKHMGJ_02372 1.4e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEFKHMGJ_02373 1.09e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NEFKHMGJ_02374 1.26e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NEFKHMGJ_02375 5.85e-139 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
NEFKHMGJ_02376 6.08e-253 - - - K - - - WYL domain
NEFKHMGJ_02377 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEFKHMGJ_02378 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEFKHMGJ_02379 1.29e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEFKHMGJ_02380 0.0 - - - M - - - domain protein
NEFKHMGJ_02381 4.04e-109 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
NEFKHMGJ_02382 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEFKHMGJ_02383 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEFKHMGJ_02384 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEFKHMGJ_02385 7.17e-104 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NEFKHMGJ_02395 4.61e-93 - - - S - - - COG NOG38524 non supervised orthologous group
NEFKHMGJ_02398 1.45e-46 - - - - - - - -
NEFKHMGJ_02399 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEFKHMGJ_02400 1.12e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEFKHMGJ_02401 1.71e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEFKHMGJ_02402 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEFKHMGJ_02403 2.04e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEFKHMGJ_02404 2.27e-306 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEFKHMGJ_02405 3.52e-106 yabR - - J ko:K07571 - ko00000 RNA binding
NEFKHMGJ_02406 1.87e-84 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
NEFKHMGJ_02407 2.33e-52 yabO - - J - - - S4 domain protein
NEFKHMGJ_02408 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEFKHMGJ_02409 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEFKHMGJ_02410 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEFKHMGJ_02411 2.92e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEFKHMGJ_02412 0.0 - - - S - - - Putative peptidoglycan binding domain
NEFKHMGJ_02413 6.37e-125 padR - - K - - - Transcriptional regulator PadR-like family
NEFKHMGJ_02414 0.0 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
NEFKHMGJ_02415 3.35e-148 - - - S - - - Flavodoxin-like fold
NEFKHMGJ_02416 7.74e-154 - - - S - - - (CBS) domain
NEFKHMGJ_02417 2.31e-165 yciB - - M - - - ErfK YbiS YcfS YnhG
NEFKHMGJ_02418 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NEFKHMGJ_02419 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
NEFKHMGJ_02420 3.27e-112 queT - - S - - - QueT transporter
NEFKHMGJ_02421 2.32e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NEFKHMGJ_02422 5.46e-51 - - - - - - - -
NEFKHMGJ_02423 5.02e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEFKHMGJ_02424 2.25e-83 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEFKHMGJ_02425 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEFKHMGJ_02426 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEFKHMGJ_02427 7.21e-189 - - - - - - - -
NEFKHMGJ_02428 3.88e-159 - - - S - - - Tetratricopeptide repeat
NEFKHMGJ_02429 1.83e-158 - - - - - - - -
NEFKHMGJ_02430 3.27e-96 - - - - - - - -
NEFKHMGJ_02431 3.24e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEFKHMGJ_02432 2.72e-299 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEFKHMGJ_02433 0.0 - - - L - - - PFAM Integrase core domain
NEFKHMGJ_02434 1.56e-24 - - - - - - - -
NEFKHMGJ_02436 3.66e-07 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEFKHMGJ_02438 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEFKHMGJ_02439 9.47e-281 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEFKHMGJ_02442 4.28e-195 ybbB - - S - - - Protein of unknown function (DUF1211)
NEFKHMGJ_02443 2.69e-103 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEFKHMGJ_02444 1.72e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
NEFKHMGJ_02445 2.83e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NEFKHMGJ_02446 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NEFKHMGJ_02447 6.22e-107 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEFKHMGJ_02448 2.05e-235 - - - S - - - DUF218 domain
NEFKHMGJ_02449 1.4e-78 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEFKHMGJ_02450 1.36e-94 - - - - - - - -
NEFKHMGJ_02451 1.34e-68 nudA - - S - - - ASCH
NEFKHMGJ_02452 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEFKHMGJ_02453 2.22e-297 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEFKHMGJ_02455 1.3e-281 ysaA - - V - - - RDD family
NEFKHMGJ_02456 5.87e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NEFKHMGJ_02457 1.84e-154 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02458 2.5e-159 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NEFKHMGJ_02459 6.67e-204 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NEFKHMGJ_02460 4.38e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEFKHMGJ_02461 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
NEFKHMGJ_02462 6.29e-194 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEFKHMGJ_02463 2.76e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEFKHMGJ_02464 3.71e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NEFKHMGJ_02465 1.36e-105 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NEFKHMGJ_02466 4.53e-238 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
NEFKHMGJ_02467 5.82e-219 yqhA - - G - - - Aldose 1-epimerase
NEFKHMGJ_02468 2.89e-160 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEFKHMGJ_02469 2.86e-215 - - - T - - - GHKL domain
NEFKHMGJ_02470 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEFKHMGJ_02471 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEFKHMGJ_02472 9.64e-42 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
NEFKHMGJ_02473 3.43e-85 - - - - - - - -
NEFKHMGJ_02474 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEFKHMGJ_02475 4.67e-222 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEFKHMGJ_02476 1.54e-189 yunF - - F - - - Protein of unknown function DUF72
NEFKHMGJ_02477 9.01e-118 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEFKHMGJ_02478 1.8e-217 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEFKHMGJ_02479 5.76e-140 yiiE - - S - - - Protein of unknown function (DUF1211)
NEFKHMGJ_02480 3.42e-166 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
NEFKHMGJ_02481 7.77e-25 - - - - - - - -
NEFKHMGJ_02482 8.88e-217 - - - - - - - -
NEFKHMGJ_02483 5.54e-126 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEFKHMGJ_02484 3.78e-51 - - - - - - - -
NEFKHMGJ_02485 3.46e-219 ypuA - - S - - - Protein of unknown function (DUF1002)
NEFKHMGJ_02486 5.8e-220 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEFKHMGJ_02487 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEFKHMGJ_02488 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEFKHMGJ_02489 1.95e-221 ydhF - - S - - - Aldo keto reductase
NEFKHMGJ_02490 2.94e-198 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NEFKHMGJ_02491 2.77e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NEFKHMGJ_02492 1.3e-302 dinF - - V - - - MatE
NEFKHMGJ_02493 6.41e-141 - - - S ko:K06872 - ko00000 TPM domain
NEFKHMGJ_02494 4.87e-134 lemA - - S ko:K03744 - ko00000 LemA family
NEFKHMGJ_02495 6.02e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEFKHMGJ_02496 2.4e-104 - - - - - - - -
NEFKHMGJ_02497 5.19e-32 - - - - - - - -
NEFKHMGJ_02499 2.48e-150 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEFKHMGJ_02501 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEFKHMGJ_02502 4.27e-225 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02503 0.0 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEFKHMGJ_02504 0.0 - - - L - - - DNA helicase
NEFKHMGJ_02505 1.1e-189 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NEFKHMGJ_02506 1.95e-223 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
NEFKHMGJ_02507 1.49e-139 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEFKHMGJ_02509 0.0 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_02510 1.32e-137 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEFKHMGJ_02511 4.69e-94 - - - K - - - MarR family
NEFKHMGJ_02512 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NEFKHMGJ_02513 6.23e-244 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NEFKHMGJ_02514 1.32e-183 - - - S - - - hydrolase
NEFKHMGJ_02515 3.33e-78 - - - - - - - -
NEFKHMGJ_02516 1.71e-17 - - - - - - - -
NEFKHMGJ_02518 1.5e-31 - - - - - - - -
NEFKHMGJ_02520 1.24e-79 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_02522 5.58e-151 - - - S - - - Protein of unknown function (DUF1275)
NEFKHMGJ_02523 1.45e-162 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NEFKHMGJ_02524 8.09e-194 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEFKHMGJ_02525 1.38e-117 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEFKHMGJ_02526 2.17e-213 - - - K - - - LysR substrate binding domain
NEFKHMGJ_02527 1.66e-288 - - - EK - - - Aminotransferase, class I
NEFKHMGJ_02528 9.07e-61 - - - - - - - -
NEFKHMGJ_02529 5.18e-75 - - - - - - - -
NEFKHMGJ_02530 3.1e-254 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEFKHMGJ_02531 5.11e-149 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEFKHMGJ_02532 2.13e-115 - - - - - - - -
NEFKHMGJ_02534 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_02535 1.59e-215 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_02536 1e-168 rpl - - K - - - Helix-turn-helix domain, rpiR family
NEFKHMGJ_02537 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEFKHMGJ_02538 1.55e-116 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NEFKHMGJ_02539 1.6e-188 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NEFKHMGJ_02540 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NEFKHMGJ_02541 1.32e-132 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEFKHMGJ_02542 2.21e-309 - - - P - - - Sodium:sulfate symporter transmembrane region
NEFKHMGJ_02543 8.07e-204 - - - K - - - LysR substrate binding domain
NEFKHMGJ_02544 3.13e-99 - - - - - - - -
NEFKHMGJ_02545 2.37e-95 - - - K - - - Transcriptional regulator
NEFKHMGJ_02546 3.68e-311 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NEFKHMGJ_02547 1.22e-165 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
NEFKHMGJ_02549 7.84e-317 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_02550 6.21e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02551 4.19e-89 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_02552 1.86e-154 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEFKHMGJ_02553 1.86e-212 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NEFKHMGJ_02554 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NEFKHMGJ_02555 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NEFKHMGJ_02556 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEFKHMGJ_02557 0.0 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NEFKHMGJ_02558 4.24e-247 - - - K - - - helix_turn_helix, arabinose operon control protein
NEFKHMGJ_02559 1.23e-274 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NEFKHMGJ_02560 1.35e-85 - - - S - - - Protein of unknown function (DUF1093)
NEFKHMGJ_02561 9.19e-155 - - - - - - - -
NEFKHMGJ_02562 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEFKHMGJ_02563 0.0 - - - M - - - Right handed beta helix region
NEFKHMGJ_02564 1.09e-98 - - - - - - - -
NEFKHMGJ_02565 0.0 - - - M - - - Heparinase II/III N-terminus
NEFKHMGJ_02567 1.78e-86 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEFKHMGJ_02568 7.09e-184 agaD - - G ko:K02747 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NEFKHMGJ_02569 4.89e-172 - - - G ko:K02746 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_02570 1.2e-105 - - - G ko:K02745 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_02571 3.82e-258 ugl 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NEFKHMGJ_02572 1.2e-129 - - - S - - - Psort location Cytoplasmic, score
NEFKHMGJ_02573 6.48e-140 - - - K - - - Bacterial transcriptional regulator
NEFKHMGJ_02574 6.27e-182 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NEFKHMGJ_02575 2.15e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEFKHMGJ_02576 8.35e-115 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NEFKHMGJ_02577 8e-192 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
NEFKHMGJ_02578 8.99e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEFKHMGJ_02580 0.0 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
NEFKHMGJ_02581 5.82e-250 - - - G - - - Melibiase
NEFKHMGJ_02582 6.48e-52 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_02583 5.55e-83 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NEFKHMGJ_02584 2.21e-79 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_02585 4.58e-30 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
NEFKHMGJ_02586 6.05e-65 araR - - K ko:K02103 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEFKHMGJ_02587 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
NEFKHMGJ_02588 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEFKHMGJ_02590 1.47e-160 - - - K - - - Helix-turn-helix domain, rpiR family
NEFKHMGJ_02591 4.98e-107 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEFKHMGJ_02592 5.63e-177 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
NEFKHMGJ_02593 3.56e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
NEFKHMGJ_02594 6.07e-275 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
NEFKHMGJ_02595 3.36e-153 - - - S - - - Domain of unknown function (DUF4310)
NEFKHMGJ_02596 2.89e-177 - - - S - - - Domain of unknown function (DUF4311)
NEFKHMGJ_02597 1.66e-75 - - - S - - - Domain of unknown function (DUF4312)
NEFKHMGJ_02598 1.23e-80 - - - S - - - Glycine-rich SFCGS
NEFKHMGJ_02599 1.62e-71 - - - S - - - PRD domain
NEFKHMGJ_02600 0.0 - - - K - - - Mga helix-turn-helix domain
NEFKHMGJ_02601 4.85e-158 - - - H - - - Pfam:Transaldolase
NEFKHMGJ_02602 1.74e-82 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEFKHMGJ_02603 5.39e-252 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NEFKHMGJ_02604 1.43e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NEFKHMGJ_02605 4.36e-114 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NEFKHMGJ_02606 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NEFKHMGJ_02607 8.33e-185 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NEFKHMGJ_02608 2.14e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEFKHMGJ_02609 1.02e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEFKHMGJ_02610 5.14e-214 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
NEFKHMGJ_02611 3.66e-177 - - - K - - - DeoR C terminal sensor domain
NEFKHMGJ_02612 7.47e-148 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
NEFKHMGJ_02613 6.78e-61 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02614 0.0 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEFKHMGJ_02615 2.42e-105 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEFKHMGJ_02616 1.21e-270 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
NEFKHMGJ_02617 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NEFKHMGJ_02618 9.05e-55 - - - - - - - -
NEFKHMGJ_02619 1.69e-200 - - - GK - - - ROK family
NEFKHMGJ_02620 1.5e-230 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NEFKHMGJ_02621 2.27e-315 - - - E - - - Peptidase family M20/M25/M40
NEFKHMGJ_02622 5.02e-168 - - - K ko:K03710 - ko00000,ko03000 UTRA
NEFKHMGJ_02623 8.28e-273 - - - EGP - - - Transporter, major facilitator family protein
NEFKHMGJ_02624 9.84e-264 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NEFKHMGJ_02625 4.6e-196 - - - GM - - - NAD dependent epimerase/dehydratase family
NEFKHMGJ_02626 2.26e-144 - - - S - - - DJ-1/PfpI family
NEFKHMGJ_02627 5.87e-62 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEFKHMGJ_02628 6.5e-119 - - - K ko:K03828 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEFKHMGJ_02629 4.16e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NEFKHMGJ_02630 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
NEFKHMGJ_02631 5.05e-171 - - - F - - - NUDIX domain
NEFKHMGJ_02632 9.35e-140 pncA - - Q - - - Isochorismatase family
NEFKHMGJ_02633 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEFKHMGJ_02634 2.14e-170 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEFKHMGJ_02635 5.05e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEFKHMGJ_02636 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEFKHMGJ_02637 6.89e-191 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_02638 1.76e-208 - - - P ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type sugar transport systems, permease components
NEFKHMGJ_02639 3.09e-267 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NEFKHMGJ_02640 1.94e-288 - - - EGP - - - Transmembrane secretion effector
NEFKHMGJ_02641 4.15e-187 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEFKHMGJ_02642 1.04e-243 - - - V - - - Beta-lactamase
NEFKHMGJ_02643 1.53e-187 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEFKHMGJ_02644 1.1e-209 - - - K - - - Helix-turn-helix domain, rpiR family
NEFKHMGJ_02645 7.93e-104 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_02646 5.03e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NEFKHMGJ_02647 1.88e-168 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NEFKHMGJ_02649 7.17e-258 - - - S - - - endonuclease exonuclease phosphatase family protein
NEFKHMGJ_02650 1.65e-213 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NEFKHMGJ_02651 9.84e-184 - - - Q - - - Methyltransferase
NEFKHMGJ_02652 1.25e-67 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NEFKHMGJ_02653 2.44e-07 - - - K - - - SpoVT / AbrB like domain
NEFKHMGJ_02654 4.22e-173 - - - V - - - ABC transporter transmembrane region
NEFKHMGJ_02655 1.33e-77 - - - - - - - -
NEFKHMGJ_02656 1.78e-49 - - - - - - - -
NEFKHMGJ_02657 1.4e-140 - - - S - - - alpha beta
NEFKHMGJ_02658 3.49e-113 yfbM - - K - - - FR47-like protein
NEFKHMGJ_02659 3.24e-169 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEFKHMGJ_02660 2.21e-109 - - - K - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_02661 1.45e-159 - - - - - - - -
NEFKHMGJ_02662 1.69e-89 - - - S - - - ASCH
NEFKHMGJ_02663 2.89e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEFKHMGJ_02664 7.69e-254 ysdE - - P - - - Citrate transporter
NEFKHMGJ_02665 1.17e-136 - - - - - - - -
NEFKHMGJ_02666 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NEFKHMGJ_02667 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEFKHMGJ_02668 2.7e-204 - - - - - - - -
NEFKHMGJ_02669 0.0 cadA - - P - - - P-type ATPase
NEFKHMGJ_02670 3.36e-98 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
NEFKHMGJ_02671 1.94e-91 - - - S - - - Iron-sulphur cluster biosynthesis
NEFKHMGJ_02672 1.99e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NEFKHMGJ_02673 1.11e-07 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEFKHMGJ_02674 4.51e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NEFKHMGJ_02675 3.66e-183 yycI - - S - - - YycH protein
NEFKHMGJ_02676 0.0 yycH - - S - - - YycH protein
NEFKHMGJ_02677 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEFKHMGJ_02678 5.24e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEFKHMGJ_02679 2.14e-157 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
NEFKHMGJ_02680 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_02681 4.66e-298 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEFKHMGJ_02682 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NEFKHMGJ_02683 3.77e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEFKHMGJ_02684 3.7e-96 - - - S - - - Domain of unknown function (DUF3284)
NEFKHMGJ_02685 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEFKHMGJ_02686 8.04e-168 - - - K - - - UbiC transcription regulator-associated domain protein
NEFKHMGJ_02687 2.7e-68 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02688 2.91e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NEFKHMGJ_02689 3.03e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NEFKHMGJ_02690 2.67e-104 - - - F - - - NUDIX domain
NEFKHMGJ_02691 1.7e-117 - - - S - - - AAA domain
NEFKHMGJ_02692 2.24e-146 ycaC - - Q - - - Isochorismatase family
NEFKHMGJ_02693 3.1e-243 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_02694 1.07e-52 - - - EGP - - - Major Facilitator Superfamily
NEFKHMGJ_02695 3.01e-273 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NEFKHMGJ_02696 7.35e-221 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NEFKHMGJ_02697 2.19e-84 manO - - S - - - Domain of unknown function (DUF956)
NEFKHMGJ_02698 7.33e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NEFKHMGJ_02699 6.18e-173 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NEFKHMGJ_02700 7.73e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEFKHMGJ_02701 5.9e-280 - - - EGP - - - Major facilitator Superfamily
NEFKHMGJ_02702 2.33e-239 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
NEFKHMGJ_02703 5.87e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
NEFKHMGJ_02704 2.41e-201 - - - K - - - sequence-specific DNA binding
NEFKHMGJ_02708 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NEFKHMGJ_02709 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEFKHMGJ_02710 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02711 2.19e-52 - - - - - - - -
NEFKHMGJ_02712 1.93e-302 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEFKHMGJ_02713 9e-166 - - - S - - - Protein of unknown function (DUF975)
NEFKHMGJ_02714 7.92e-76 - - - S - - - Iron-sulphur cluster biosynthesis
NEFKHMGJ_02715 9.87e-70 - - - - - - - -
NEFKHMGJ_02716 1.9e-104 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NEFKHMGJ_02717 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
NEFKHMGJ_02718 5.46e-186 - - - S - - - AAA ATPase domain
NEFKHMGJ_02719 1.73e-213 - - - G - - - Phosphotransferase enzyme family
NEFKHMGJ_02720 7.69e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEFKHMGJ_02721 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_02722 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEFKHMGJ_02723 1.33e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEFKHMGJ_02724 2.9e-133 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
NEFKHMGJ_02725 1.84e-211 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEFKHMGJ_02726 1.59e-168 - - - S - - - Protein of unknown function DUF58
NEFKHMGJ_02727 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
NEFKHMGJ_02728 7.06e-272 - - - M - - - Glycosyl transferases group 1
NEFKHMGJ_02729 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NEFKHMGJ_02730 4.25e-144 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NEFKHMGJ_02731 9.76e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NEFKHMGJ_02734 9.57e-252 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NEFKHMGJ_02735 5.16e-290 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
NEFKHMGJ_02736 0.0 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
NEFKHMGJ_02737 1.74e-154 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
NEFKHMGJ_02738 4.64e-129 - - - - - - - -
NEFKHMGJ_02739 5.58e-22 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEFKHMGJ_02740 3.39e-193 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
NEFKHMGJ_02741 3.93e-90 - - - - - - - -
NEFKHMGJ_02742 4.52e-169 - - - F - - - Glutamine amidotransferase class-I
NEFKHMGJ_02743 7.89e-216 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NEFKHMGJ_02744 1.67e-286 - - - G - - - phosphotransferase system
NEFKHMGJ_02745 4.14e-127 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEFKHMGJ_02747 3.77e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEFKHMGJ_02748 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
NEFKHMGJ_02749 9.48e-237 lipA - - I - - - Carboxylesterase family
NEFKHMGJ_02750 1.75e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NEFKHMGJ_02751 5.35e-102 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEFKHMGJ_02752 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NEFKHMGJ_02753 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEFKHMGJ_02754 2.92e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEFKHMGJ_02755 9.1e-191 - - - S - - - haloacid dehalogenase-like hydrolase
NEFKHMGJ_02756 7.2e-60 - - - - - - - -
NEFKHMGJ_02757 1.29e-25 - - - - - - - -
NEFKHMGJ_02758 2.47e-175 - - - - - - - -
NEFKHMGJ_02759 3.3e-280 - - - K - - - IrrE N-terminal-like domain
NEFKHMGJ_02760 6.5e-197 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEFKHMGJ_02761 2.05e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEFKHMGJ_02762 2.73e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEFKHMGJ_02763 9.47e-234 - - - - - - - -
NEFKHMGJ_02764 0.0 - - - M - - - Leucine rich repeats (6 copies)
NEFKHMGJ_02765 1.93e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEFKHMGJ_02766 2.49e-183 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NEFKHMGJ_02767 2.21e-191 - - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NEFKHMGJ_02770 4.28e-253 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
NEFKHMGJ_02771 2.1e-285 amd - - E - - - Peptidase family M20/M25/M40
NEFKHMGJ_02772 1.8e-105 - - - S - - - Threonine/Serine exporter, ThrE
NEFKHMGJ_02773 1.73e-171 - - - S - - - Putative threonine/serine exporter
NEFKHMGJ_02775 5.65e-42 - - - - - - - -
NEFKHMGJ_02776 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NEFKHMGJ_02777 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEFKHMGJ_02778 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEFKHMGJ_02779 3.01e-177 jag - - S ko:K06346 - ko00000 R3H domain protein
NEFKHMGJ_02780 8.28e-182 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEFKHMGJ_02781 1.56e-78 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEFKHMGJ_02782 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)