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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
APCIGHGI_00001	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APCIGHGI_00002	1.52e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
APCIGHGI_00003	2.2e-250	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
APCIGHGI_00004	5.39e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APCIGHGI_00005	9.49e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APCIGHGI_00006	2.13e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
APCIGHGI_00007	8.45e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
APCIGHGI_00008	2.06e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
APCIGHGI_00009	8.81e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APCIGHGI_00010	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APCIGHGI_00031	8.34e-101	-	-	-	-	-	-	-	-
APCIGHGI_00032	8.89e-137	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
APCIGHGI_00033	5.23e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
APCIGHGI_00034	1.01e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APCIGHGI_00035	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
APCIGHGI_00036	2.73e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APCIGHGI_00037	1.59e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APCIGHGI_00038	5.07e-202	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
APCIGHGI_00043	5.67e-57	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
APCIGHGI_00044	4.12e-210	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
APCIGHGI_00045	1.09e-227	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
APCIGHGI_00046	3.42e-194	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
APCIGHGI_00047	7.4e-184	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
APCIGHGI_00048	5.95e-119	-	-	-	M	-	-	-	PFAM NLP P60 protein
APCIGHGI_00049	9.01e-314	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_00050	2.04e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
APCIGHGI_00051	2.83e-181	-	-	-	-	-	-	-	-
APCIGHGI_00052	5.94e-238	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
APCIGHGI_00053	1.08e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APCIGHGI_00054	4.62e-92	-	-	-	-	-	-	-	-
APCIGHGI_00055	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APCIGHGI_00056	3.7e-201	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
APCIGHGI_00057	1.75e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
APCIGHGI_00058	3.89e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
APCIGHGI_00059	3.09e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APCIGHGI_00060	1.83e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
APCIGHGI_00061	1.96e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
APCIGHGI_00062	1.53e-285	-	-	-	P	-	-	-	Chloride transporter, ClC family
APCIGHGI_00063	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APCIGHGI_00064	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APCIGHGI_00065	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
APCIGHGI_00066	1.07e-209	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APCIGHGI_00067	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
APCIGHGI_00068	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APCIGHGI_00069	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
APCIGHGI_00070	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APCIGHGI_00071	8.44e-301	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APCIGHGI_00072	3.41e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
APCIGHGI_00073	1.11e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APCIGHGI_00074	4.41e-226	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
APCIGHGI_00075	5.98e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APCIGHGI_00076	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APCIGHGI_00077	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APCIGHGI_00078	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APCIGHGI_00079	2.27e-305	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
APCIGHGI_00080	3.91e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APCIGHGI_00081	1.62e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
APCIGHGI_00082	7.28e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APCIGHGI_00083	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
APCIGHGI_00084	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
APCIGHGI_00085	4.68e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
APCIGHGI_00086	1.65e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
APCIGHGI_00087	8.07e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00088	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APCIGHGI_00089	2.59e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
APCIGHGI_00090	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
APCIGHGI_00091	5.44e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
APCIGHGI_00092	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
APCIGHGI_00093	9.45e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
APCIGHGI_00094	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APCIGHGI_00095	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APCIGHGI_00099	1.11e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
APCIGHGI_00100	1.13e-277	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
APCIGHGI_00101	2.03e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APCIGHGI_00102	1.43e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
APCIGHGI_00103	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APCIGHGI_00104	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APCIGHGI_00106	8.61e-35	-	-	-	S	-	-	-	YjcQ protein
APCIGHGI_00107	6.07e-190	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APCIGHGI_00108	2.3e-173	-	-	-	S	-	-	-	Membrane
APCIGHGI_00109	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
APCIGHGI_00110	6.61e-110	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
APCIGHGI_00111	7.51e-300	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APCIGHGI_00113	5e-106	uspA	-	-	T	-	-	-	universal stress protein
APCIGHGI_00114	7.75e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APCIGHGI_00115	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
APCIGHGI_00116	9.42e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
APCIGHGI_00118	2.95e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
APCIGHGI_00119	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
APCIGHGI_00120	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
APCIGHGI_00121	2.3e-276	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
APCIGHGI_00122	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
APCIGHGI_00123	2.8e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
APCIGHGI_00124	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APCIGHGI_00125	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APCIGHGI_00126	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APCIGHGI_00127	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APCIGHGI_00128	3.92e-80	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APCIGHGI_00129	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APCIGHGI_00130	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
APCIGHGI_00131	3.15e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
APCIGHGI_00132	1.35e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
APCIGHGI_00133	8.52e-254	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
APCIGHGI_00134	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APCIGHGI_00135	9e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APCIGHGI_00136	2.77e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APCIGHGI_00137	1.92e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APCIGHGI_00138	5.36e-208	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APCIGHGI_00139	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
APCIGHGI_00140	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
APCIGHGI_00141	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
APCIGHGI_00142	2.31e-63	-	-	-	-	-	-	-	-
APCIGHGI_00143	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APCIGHGI_00144	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
APCIGHGI_00145	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APCIGHGI_00146	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00147	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
APCIGHGI_00148	4.76e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00149	3.24e-10	-	-	-	-	-	-	-	-
APCIGHGI_00151	1.27e-73	-	-	-	-	-	-	-	-
APCIGHGI_00153	5.24e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
APCIGHGI_00154	5.46e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APCIGHGI_00155	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
APCIGHGI_00156	1.09e-159	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
APCIGHGI_00157	2.89e-110	-	-	-	K	-	-	-	GNAT family
APCIGHGI_00159	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
APCIGHGI_00160	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
APCIGHGI_00161	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
APCIGHGI_00162	5.46e-237	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00163	6.73e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_00164	1.21e-53	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00165	2.62e-200	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_00166	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
APCIGHGI_00167	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
APCIGHGI_00168	8.66e-89	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APCIGHGI_00169	1.91e-157	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APCIGHGI_00170	4.47e-276	xylR	-	-	GK	-	-	-	ROK family
APCIGHGI_00171	1.24e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
APCIGHGI_00172	0.0	yclK	-	-	T	-	-	-	Histidine kinase
APCIGHGI_00173	5.65e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
APCIGHGI_00175	1.8e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
APCIGHGI_00176	1.37e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
APCIGHGI_00177	1.38e-163	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
APCIGHGI_00178	9.04e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APCIGHGI_00179	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
APCIGHGI_00180	1.25e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
APCIGHGI_00181	1.82e-190	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
APCIGHGI_00182	2.56e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
APCIGHGI_00183	4.42e-111	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_00184	2.52e-81	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_00185	6.96e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
APCIGHGI_00186	7.87e-112	lytE	-	-	M	-	-	-	Lysin motif
APCIGHGI_00187	6.1e-193	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APCIGHGI_00188	1.44e-263	oatA	-	-	I	-	-	-	Acyltransferase
APCIGHGI_00189	2.55e-68	-	-	-	-	-	-	-	-
APCIGHGI_00190	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APCIGHGI_00191	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APCIGHGI_00192	2.4e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
APCIGHGI_00193	2.29e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APCIGHGI_00194	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
APCIGHGI_00195	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APCIGHGI_00196	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APCIGHGI_00197	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
APCIGHGI_00198	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
APCIGHGI_00199	4.52e-175	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APCIGHGI_00200	2.36e-139	-	-	-	-	-	-	-	-
APCIGHGI_00201	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APCIGHGI_00202	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APCIGHGI_00203	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APCIGHGI_00204	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APCIGHGI_00205	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
APCIGHGI_00206	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APCIGHGI_00207	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APCIGHGI_00208	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
APCIGHGI_00209	7.58e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APCIGHGI_00210	3.82e-23	-	-	-	-	-	-	-	-
APCIGHGI_00211	6.22e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_00215	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APCIGHGI_00216	4.21e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00217	1.35e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00218	1.16e-47	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APCIGHGI_00219	5.22e-73	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APCIGHGI_00220	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
APCIGHGI_00221	2e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
APCIGHGI_00222	5.51e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
APCIGHGI_00223	1.25e-261	-	-	-	-	-	-	-	-
APCIGHGI_00224	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APCIGHGI_00225	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APCIGHGI_00227	5.06e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
APCIGHGI_00228	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APCIGHGI_00229	1.2e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
APCIGHGI_00230	2.76e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APCIGHGI_00231	3.96e-253	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
APCIGHGI_00232	4.22e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APCIGHGI_00233	3.44e-200	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
APCIGHGI_00234	8.22e-167	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APCIGHGI_00235	4.01e-104	yphH	-	-	S	-	-	-	Cupin domain
APCIGHGI_00236	1.25e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APCIGHGI_00237	1.08e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APCIGHGI_00238	8.73e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
APCIGHGI_00239	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
APCIGHGI_00240	9.09e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
APCIGHGI_00241	9.22e-210	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APCIGHGI_00242	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APCIGHGI_00243	2.4e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
APCIGHGI_00244	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
APCIGHGI_00245	5.89e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APCIGHGI_00246	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APCIGHGI_00247	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APCIGHGI_00248	1.07e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
APCIGHGI_00249	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
APCIGHGI_00250	1.7e-148	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
APCIGHGI_00251	4.12e-50	-	-	-	-	-	-	-	-
APCIGHGI_00252	0.0	ydaO	-	-	E	-	-	-	amino acid
APCIGHGI_00253	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APCIGHGI_00254	9.49e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APCIGHGI_00255	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APCIGHGI_00256	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
APCIGHGI_00257	1.27e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APCIGHGI_00258	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
APCIGHGI_00259	3.12e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
APCIGHGI_00260	2.69e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
APCIGHGI_00261	2.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APCIGHGI_00262	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
APCIGHGI_00263	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APCIGHGI_00264	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APCIGHGI_00265	5.39e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APCIGHGI_00266	4.42e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
APCIGHGI_00267	1.6e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
APCIGHGI_00268	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APCIGHGI_00269	5.34e-219	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APCIGHGI_00270	2.66e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
APCIGHGI_00271	4.47e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APCIGHGI_00273	6.04e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APCIGHGI_00274	7.57e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
APCIGHGI_00275	6.83e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
APCIGHGI_00276	1.61e-274	arcT	-	-	E	-	-	-	Aminotransferase
APCIGHGI_00277	2.8e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
APCIGHGI_00278	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
APCIGHGI_00279	3.45e-305	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
APCIGHGI_00280	1.66e-217	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
APCIGHGI_00281	6.7e-150	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APCIGHGI_00282	6.14e-63	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APCIGHGI_00283	2.73e-203	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
APCIGHGI_00284	8.55e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APCIGHGI_00285	1.67e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APCIGHGI_00286	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APCIGHGI_00287	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APCIGHGI_00288	1.64e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
APCIGHGI_00289	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APCIGHGI_00290	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
APCIGHGI_00291	3.22e-245	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APCIGHGI_00292	1.11e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
APCIGHGI_00293	5.68e-148	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APCIGHGI_00294	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
APCIGHGI_00295	1.31e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APCIGHGI_00296	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APCIGHGI_00297	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APCIGHGI_00299	2.13e-112	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APCIGHGI_00300	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
APCIGHGI_00301	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APCIGHGI_00302	2.56e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APCIGHGI_00303	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APCIGHGI_00304	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
APCIGHGI_00305	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APCIGHGI_00306	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APCIGHGI_00307	2.14e-187	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
APCIGHGI_00308	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
APCIGHGI_00309	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APCIGHGI_00310	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APCIGHGI_00311	2.59e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
APCIGHGI_00312	1.68e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APCIGHGI_00313	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APCIGHGI_00314	1.97e-125	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
APCIGHGI_00315	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APCIGHGI_00316	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APCIGHGI_00317	3.23e-134	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
APCIGHGI_00318	2.04e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APCIGHGI_00319	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APCIGHGI_00320	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APCIGHGI_00321	9.63e-130	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
APCIGHGI_00322	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APCIGHGI_00323	1.3e-262	yacL	-	-	S	-	-	-	domain protein
APCIGHGI_00324	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APCIGHGI_00325	3.55e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
APCIGHGI_00326	6.52e-73	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
APCIGHGI_00327	3.53e-158	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APCIGHGI_00328	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
APCIGHGI_00329	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
APCIGHGI_00330	2.18e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APCIGHGI_00331	5.85e-159	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APCIGHGI_00332	1.77e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
APCIGHGI_00333	7.85e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
APCIGHGI_00334	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
APCIGHGI_00336	1.41e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
APCIGHGI_00337	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
APCIGHGI_00338	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APCIGHGI_00339	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APCIGHGI_00340	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
APCIGHGI_00341	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
APCIGHGI_00342	5.68e-150	-	-	-	-	-	-	-	-
APCIGHGI_00345	6.76e-212	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APCIGHGI_00346	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
APCIGHGI_00347	3.21e-251	-	-	-	D	-	-	-	nuclear chromosome segregation
APCIGHGI_00348	4.29e-203	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
APCIGHGI_00349	3.44e-144	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_00352	8.34e-101	-	-	-	-	-	-	-	-
APCIGHGI_00355	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
APCIGHGI_00356	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APCIGHGI_00357	3.89e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APCIGHGI_00358	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APCIGHGI_00359	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
APCIGHGI_00360	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APCIGHGI_00361	3.89e-112	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
APCIGHGI_00362	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
APCIGHGI_00363	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
APCIGHGI_00364	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APCIGHGI_00365	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APCIGHGI_00366	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
APCIGHGI_00367	7.09e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
APCIGHGI_00368	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APCIGHGI_00369	6.85e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APCIGHGI_00370	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APCIGHGI_00371	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APCIGHGI_00372	3.83e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
APCIGHGI_00373	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
APCIGHGI_00374	7.41e-61	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APCIGHGI_00375	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
APCIGHGI_00376	3.4e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00377	1.58e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00378	1.75e-96	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
APCIGHGI_00379	4.35e-60	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
APCIGHGI_00380	7.77e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
APCIGHGI_00381	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APCIGHGI_00382	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APCIGHGI_00383	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APCIGHGI_00384	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
APCIGHGI_00385	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
APCIGHGI_00386	1.01e-184	yidA	-	-	S	-	-	-	hydrolase
APCIGHGI_00387	3.55e-76	-	-	-	-	-	-	-	-
APCIGHGI_00388	7.69e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APCIGHGI_00389	8.13e-301	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APCIGHGI_00390	2.13e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
APCIGHGI_00391	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
APCIGHGI_00392	1.98e-123	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APCIGHGI_00393	2.34e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APCIGHGI_00394	4.04e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APCIGHGI_00395	1.46e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APCIGHGI_00396	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APCIGHGI_00397	6.64e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
APCIGHGI_00398	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APCIGHGI_00399	2.85e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
APCIGHGI_00400	9.26e-270	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
APCIGHGI_00401	2.85e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00402	1.56e-163	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
APCIGHGI_00403	2.63e-239	-	-	-	-	-	-	-	-
APCIGHGI_00404	2.25e-285	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
APCIGHGI_00405	7.95e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APCIGHGI_00406	0.0	-	-	-	L	-	-	-	DNA helicase
APCIGHGI_00407	6.37e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APCIGHGI_00408	2.71e-198	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APCIGHGI_00410	1.23e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
APCIGHGI_00412	1.2e-85	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_00413	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
APCIGHGI_00414	8.97e-252	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
APCIGHGI_00415	1.69e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00416	1.58e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00417	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
APCIGHGI_00418	5.67e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APCIGHGI_00419	2.24e-159	-	-	-	C	-	-	-	nitroreductase
APCIGHGI_00420	5.22e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
APCIGHGI_00421	6.43e-100	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
APCIGHGI_00422	1.2e-36	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
APCIGHGI_00423	1.57e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF2877)
APCIGHGI_00424	1.04e-53	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
APCIGHGI_00425	3.88e-87	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
APCIGHGI_00426	3.05e-33	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
APCIGHGI_00427	1.84e-45	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
APCIGHGI_00428	3.15e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_00429	8.34e-101	-	-	-	-	-	-	-	-
APCIGHGI_00430	2.84e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
APCIGHGI_00432	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_00433	9.16e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
APCIGHGI_00434	4.45e-181	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00435	4.25e-199	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APCIGHGI_00436	7.99e-196	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
APCIGHGI_00437	1.13e-130	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
APCIGHGI_00438	2.2e-212	-	-	-	M	-	-	-	Iron Transport-associated domain
APCIGHGI_00440	3.5e-70	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APCIGHGI_00441	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_00442	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
APCIGHGI_00443	5.25e-43	-	-	-	C	-	-	-	aldo keto reductase
APCIGHGI_00444	4.85e-71	-	-	-	C	-	-	-	Aldo/keto reductase family
APCIGHGI_00448	1.51e-107	-	-	-	C	-	-	-	Aldo keto reductase
APCIGHGI_00449	5.93e-100	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
APCIGHGI_00450	4.97e-133	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
APCIGHGI_00451	1.84e-155	pnb	-	-	C	-	-	-	nitroreductase
APCIGHGI_00452	1.33e-57	yodA	-	-	S	-	-	-	Tautomerase enzyme
APCIGHGI_00453	1.11e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
APCIGHGI_00456	8.34e-101	-	-	-	-	-	-	-	-
APCIGHGI_00457	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
APCIGHGI_00458	2.22e-37	-	-	-	EGP	-	-	-	Major Facilitator
APCIGHGI_00459	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
APCIGHGI_00460	2.29e-68	-	-	-	S	-	-	-	Cupredoxin-like domain
APCIGHGI_00461	3.07e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
APCIGHGI_00462	2.03e-226	-	-	-	-	-	-	-	-
APCIGHGI_00463	2.84e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APCIGHGI_00464	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APCIGHGI_00465	1.66e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
APCIGHGI_00466	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
APCIGHGI_00467	1.13e-139	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APCIGHGI_00468	6.82e-251	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
APCIGHGI_00469	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APCIGHGI_00470	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APCIGHGI_00471	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APCIGHGI_00472	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APCIGHGI_00473	6.13e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
APCIGHGI_00474	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APCIGHGI_00475	2.8e-221	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
APCIGHGI_00476	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APCIGHGI_00477	5.86e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APCIGHGI_00478	5.81e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APCIGHGI_00479	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
APCIGHGI_00480	4.91e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
APCIGHGI_00481	2.92e-05	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
APCIGHGI_00482	7.36e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
APCIGHGI_00483	3.66e-128	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
APCIGHGI_00484	2.22e-78	-	-	-	S	-	-	-	branched-chain amino acid
APCIGHGI_00485	8.55e-188	-	-	-	E	-	-	-	AzlC protein
APCIGHGI_00486	1.68e-269	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
APCIGHGI_00487	3.09e-267	hpk31	-	-	T	-	-	-	Histidine kinase
APCIGHGI_00488	5.24e-159	vanR	-	-	K	-	-	-	response regulator
APCIGHGI_00489	3.21e-120	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
APCIGHGI_00490	2.75e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00491	1.71e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APCIGHGI_00492	7.61e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
APCIGHGI_00493	2.13e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APCIGHGI_00494	8.53e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
APCIGHGI_00495	7.52e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APCIGHGI_00496	1.91e-208	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APCIGHGI_00497	6.1e-172	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
APCIGHGI_00498	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
APCIGHGI_00499	4.43e-272	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
APCIGHGI_00500	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
APCIGHGI_00501	4.66e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00502	3.98e-288	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APCIGHGI_00504	4.91e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APCIGHGI_00506	3.66e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APCIGHGI_00507	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
APCIGHGI_00508	3.68e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APCIGHGI_00509	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
APCIGHGI_00510	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APCIGHGI_00511	6.72e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
APCIGHGI_00512	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APCIGHGI_00513	1.38e-309	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APCIGHGI_00514	2.18e-154	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
APCIGHGI_00515	1.91e-244	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APCIGHGI_00516	2.75e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00517	4.62e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APCIGHGI_00518	8.06e-280	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APCIGHGI_00519	3.68e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APCIGHGI_00520	4.22e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APCIGHGI_00521	1.34e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APCIGHGI_00522	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
APCIGHGI_00523	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APCIGHGI_00524	1.97e-62	-	-	-	-	-	-	-	-
APCIGHGI_00525	6.34e-314	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_00526	8.32e-34	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
APCIGHGI_00527	6.19e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APCIGHGI_00528	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APCIGHGI_00529	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APCIGHGI_00530	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
APCIGHGI_00531	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APCIGHGI_00532	4.66e-211	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APCIGHGI_00533	1.58e-122	-	-	-	K	-	-	-	transcriptional regulator
APCIGHGI_00534	1.13e-166	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APCIGHGI_00535	2.15e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APCIGHGI_00536	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
APCIGHGI_00537	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
APCIGHGI_00538	3.79e-315	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_00539	1.21e-208	-	-	-	C	-	-	-	Aldo keto reductase
APCIGHGI_00540	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
APCIGHGI_00541	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APCIGHGI_00542	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APCIGHGI_00543	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
APCIGHGI_00544	3.19e-45	-	-	-	-	-	-	-	-
APCIGHGI_00545	2.8e-277	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APCIGHGI_00546	7.18e-234	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_00547	2.32e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
APCIGHGI_00548	1.04e-244	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APCIGHGI_00549	2.1e-142	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
APCIGHGI_00550	3.13e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
APCIGHGI_00551	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
APCIGHGI_00552	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
APCIGHGI_00553	1.88e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_00554	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_00555	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APCIGHGI_00556	1.66e-97	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
APCIGHGI_00557	3.59e-156	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
APCIGHGI_00558	5.49e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
APCIGHGI_00559	2.05e-185	yycI	-	-	S	-	-	-	YycH protein
APCIGHGI_00560	2.45e-304	yycH	-	-	S	-	-	-	YycH protein
APCIGHGI_00561	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APCIGHGI_00562	2.13e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
APCIGHGI_00565	8.32e-66	-	-	-	-	-	-	-	-
APCIGHGI_00566	1.79e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
APCIGHGI_00567	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
APCIGHGI_00568	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APCIGHGI_00569	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
APCIGHGI_00570	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APCIGHGI_00571	6.56e-165	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APCIGHGI_00572	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
APCIGHGI_00573	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APCIGHGI_00574	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APCIGHGI_00575	6.14e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APCIGHGI_00576	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
APCIGHGI_00577	3.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APCIGHGI_00578	9.49e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APCIGHGI_00580	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
APCIGHGI_00581	2.64e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APCIGHGI_00582	4.99e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APCIGHGI_00583	5.25e-198	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
APCIGHGI_00584	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APCIGHGI_00585	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APCIGHGI_00586	1.82e-235	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00587	2.51e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_00588	2.37e-50	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00589	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00590	1.03e-75	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APCIGHGI_00591	4.35e-284	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
APCIGHGI_00592	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
APCIGHGI_00593	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APCIGHGI_00594	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APCIGHGI_00595	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
APCIGHGI_00596	3.08e-209	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
APCIGHGI_00597	2.76e-109	-	-	-	L	-	-	-	nuclease
APCIGHGI_00598	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APCIGHGI_00599	2.26e-66	-	-	-	-	-	-	-	-
APCIGHGI_00600	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
APCIGHGI_00601	1.58e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
APCIGHGI_00602	3.89e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APCIGHGI_00603	1.65e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APCIGHGI_00604	2.38e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00605	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APCIGHGI_00606	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
APCIGHGI_00607	7.65e-314	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APCIGHGI_00608	5.8e-216	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_00609	1.11e-35	-	-	-	-	-	-	-	-
APCIGHGI_00610	3.97e-137	-	-	-	-	-	-	-	-
APCIGHGI_00611	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APCIGHGI_00612	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
APCIGHGI_00613	7.49e-74	-	-	-	-	-	-	-	-
APCIGHGI_00614	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
APCIGHGI_00616	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
APCIGHGI_00617	1.16e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
APCIGHGI_00618	2.84e-263	-	-	-	S	-	-	-	associated with various cellular activities
APCIGHGI_00619	2.15e-271	-	-	-	S	-	-	-	Putative metallopeptidase domain
APCIGHGI_00620	8.5e-61	-	-	-	-	-	-	-	-
APCIGHGI_00621	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
APCIGHGI_00622	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APCIGHGI_00623	3.46e-120	ymdB	-	-	S	-	-	-	Macro domain protein
APCIGHGI_00624	8.79e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
APCIGHGI_00625	2.57e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APCIGHGI_00626	4.23e-217	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_00627	9.08e-71	-	-	-	-	-	-	-	-
APCIGHGI_00628	1.09e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
APCIGHGI_00629	3.51e-154	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APCIGHGI_00630	2.05e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00631	1.21e-48	-	-	-	-	-	-	-	-
APCIGHGI_00632	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
APCIGHGI_00633	2.04e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APCIGHGI_00634	1.9e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APCIGHGI_00635	4.19e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APCIGHGI_00636	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
APCIGHGI_00637	7.14e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
APCIGHGI_00638	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APCIGHGI_00639	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
APCIGHGI_00640	8.6e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_00641	4.27e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
APCIGHGI_00642	2.44e-66	crtM	2.5.1.32, 2.5.1.96, 2.5.1.99	-	I	ko:K02291,ko:K10208	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
APCIGHGI_00643	4.92e-225	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APCIGHGI_00644	1.52e-74	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00645	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_00646	8.85e-133	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
APCIGHGI_00647	7.13e-18	-	-	-	S	-	-	-	Homeodomain-like domain
APCIGHGI_00648	9.16e-156	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
APCIGHGI_00649	3.11e-277	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
APCIGHGI_00651	5.92e-157	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APCIGHGI_00652	1.97e-73	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_00653	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
APCIGHGI_00654	1.24e-185	-	-	-	L	-	-	-	4.5 Transposon and IS
APCIGHGI_00655	1.92e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase
APCIGHGI_00656	2.93e-159	-	-	-	S	-	-	-	Membrane
APCIGHGI_00657	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APCIGHGI_00658	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
APCIGHGI_00659	2.05e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
APCIGHGI_00660	5e-176	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APCIGHGI_00661	5.3e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
APCIGHGI_00662	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
APCIGHGI_00663	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APCIGHGI_00664	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APCIGHGI_00665	3.6e-266	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
APCIGHGI_00666	2.36e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
APCIGHGI_00667	3.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
APCIGHGI_00668	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
APCIGHGI_00669	3.4e-116	-	-	-	GM	-	-	-	epimerase
APCIGHGI_00670	1.7e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
APCIGHGI_00671	3.73e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
APCIGHGI_00672	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APCIGHGI_00673	2.19e-166	-	-	-	-	-	-	-	-
APCIGHGI_00674	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APCIGHGI_00675	6.33e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
APCIGHGI_00676	2.92e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
APCIGHGI_00677	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
APCIGHGI_00679	1.25e-153	potE	-	-	E	-	-	-	Amino Acid
APCIGHGI_00680	7.06e-188	potE	-	-	E	-	-	-	Amino Acid
APCIGHGI_00681	2.85e-242	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
APCIGHGI_00682	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
APCIGHGI_00683	1.49e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APCIGHGI_00684	1.49e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
APCIGHGI_00685	2.05e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APCIGHGI_00686	5.79e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
APCIGHGI_00687	1.59e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APCIGHGI_00688	8.61e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APCIGHGI_00689	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
APCIGHGI_00690	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APCIGHGI_00691	3.06e-63	-	-	-	L	-	-	-	Transposase DDE domain group 1
APCIGHGI_00692	3.7e-218	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_00693	4.3e-159	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
APCIGHGI_00694	8.12e-300	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
APCIGHGI_00695	1.13e-171	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
APCIGHGI_00696	6.55e-291	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
APCIGHGI_00697	7.99e-189	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
APCIGHGI_00698	2.5e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
APCIGHGI_00699	5.51e-218	-	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
APCIGHGI_00700	1.7e-225	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00701	6.48e-145	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APCIGHGI_00702	5.46e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APCIGHGI_00703	6.86e-175	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
APCIGHGI_00704	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APCIGHGI_00705	2.72e-314	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
APCIGHGI_00706	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
APCIGHGI_00708	3.44e-95	uspA3	-	-	T	-	-	-	universal stress protein
APCIGHGI_00709	6.25e-78	-	-	-	-	-	-	-	-
APCIGHGI_00710	1.25e-09	-	-	-	-	-	-	-	-
APCIGHGI_00711	7.82e-203	-	-	-	-	-	-	-	-
APCIGHGI_00712	6.36e-98	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_00713	8.79e-239	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
APCIGHGI_00714	3.85e-95	-	-	-	O	-	-	-	OsmC-like protein
APCIGHGI_00715	1.12e-245	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
APCIGHGI_00716	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
APCIGHGI_00717	1.78e-22	-	-	-	-	-	-	-	-
APCIGHGI_00718	1.06e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
APCIGHGI_00719	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00720	1.37e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
APCIGHGI_00721	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
APCIGHGI_00722	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
APCIGHGI_00723	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APCIGHGI_00724	3.19e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
APCIGHGI_00725	8.02e-130	dpsB	-	-	P	-	-	-	Belongs to the Dps family
APCIGHGI_00726	1.33e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
APCIGHGI_00727	2.92e-95	-	-	-	-	-	-	-	-
APCIGHGI_00728	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APCIGHGI_00729	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
APCIGHGI_00730	8.32e-192	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
APCIGHGI_00731	1.07e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
APCIGHGI_00732	3.77e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
APCIGHGI_00733	1.12e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
APCIGHGI_00734	1.6e-179	yceF	-	-	P	ko:K05794	-	ko00000	membrane
APCIGHGI_00735	3.45e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APCIGHGI_00736	3.57e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00737	2e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00738	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APCIGHGI_00739	6.68e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
APCIGHGI_00740	2.41e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_00741	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
APCIGHGI_00742	3.23e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
APCIGHGI_00743	1.29e-298	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
APCIGHGI_00744	4.39e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
APCIGHGI_00746	2.28e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00747	1.26e-191	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APCIGHGI_00748	1.14e-230	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
APCIGHGI_00749	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
APCIGHGI_00750	1.99e-263	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
APCIGHGI_00752	1.67e-140	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
APCIGHGI_00753	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
APCIGHGI_00754	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APCIGHGI_00755	1.08e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
APCIGHGI_00756	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
APCIGHGI_00757	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
APCIGHGI_00758	1.98e-147	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
APCIGHGI_00759	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APCIGHGI_00760	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APCIGHGI_00761	9.44e-260	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
APCIGHGI_00762	3.13e-95	-	-	-	F	-	-	-	Nudix hydrolase
APCIGHGI_00763	9.61e-137	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
APCIGHGI_00764	7.28e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
APCIGHGI_00765	2.5e-09	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
APCIGHGI_00766	5.54e-214	-	-	-	-	-	-	-	-
APCIGHGI_00767	2.38e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
APCIGHGI_00768	6.73e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
APCIGHGI_00769	3.52e-127	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
APCIGHGI_00770	1.2e-188	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
APCIGHGI_00771	1.82e-235	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00772	4.76e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00773	2.68e-34	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00774	8.49e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00775	4.58e-114	-	-	-	K	-	-	-	FR47-like protein
APCIGHGI_00776	0.0	-	-	-	E	-	-	-	amino acid
APCIGHGI_00777	3.55e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
APCIGHGI_00778	3.08e-266	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APCIGHGI_00779	9.54e-179	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APCIGHGI_00780	3.59e-94	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APCIGHGI_00781	2.61e-153	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
APCIGHGI_00782	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
APCIGHGI_00783	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
APCIGHGI_00784	7.84e-204	-	-	-	EG	-	-	-	EamA-like transporter family
APCIGHGI_00785	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APCIGHGI_00786	2.3e-134	-	-	-	K	-	-	-	acetyltransferase
APCIGHGI_00787	2.29e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
APCIGHGI_00788	5.13e-165	sptS	-	-	T	-	-	-	Histidine kinase
APCIGHGI_00789	6.69e-101	dltr	-	-	K	-	-	-	response regulator
APCIGHGI_00790	9.55e-146	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
APCIGHGI_00791	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
APCIGHGI_00792	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
APCIGHGI_00793	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
APCIGHGI_00795	3.06e-80	-	-	-	-	-	-	-	-
APCIGHGI_00796	2.52e-10	-	-	-	-	-	-	-	-
APCIGHGI_00797	1.17e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
APCIGHGI_00798	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
APCIGHGI_00799	5.38e-222	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
APCIGHGI_00800	1.1e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
APCIGHGI_00801	5.89e-96	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
APCIGHGI_00802	1.25e-55	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
APCIGHGI_00803	8.03e-146	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APCIGHGI_00804	7.11e-160	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APCIGHGI_00805	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_00806	8.36e-55	-	-	-	S	-	-	-	FMN_bind
APCIGHGI_00807	6.34e-147	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
APCIGHGI_00808	2.65e-43	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
APCIGHGI_00809	5.02e-31	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APCIGHGI_00810	1.54e-131	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_00811	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APCIGHGI_00812	4.13e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
APCIGHGI_00813	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
APCIGHGI_00814	1.6e-54	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
APCIGHGI_00815	2.16e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
APCIGHGI_00816	3.59e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APCIGHGI_00817	6.11e-106	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APCIGHGI_00818	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
APCIGHGI_00819	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APCIGHGI_00821	1.36e-195	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
APCIGHGI_00822	5.57e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APCIGHGI_00823	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
APCIGHGI_00824	1.79e-266	-	-	-	EGP	-	-	-	Major Facilitator
APCIGHGI_00825	2.11e-272	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
APCIGHGI_00826	2.85e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
APCIGHGI_00827	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
APCIGHGI_00828	1.12e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APCIGHGI_00829	2.84e-222	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
APCIGHGI_00830	1.27e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
APCIGHGI_00831	2.31e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APCIGHGI_00832	4.35e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APCIGHGI_00833	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
APCIGHGI_00834	1.16e-85	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
APCIGHGI_00835	4.73e-131	-	-	-	NU	-	-	-	mannosyl-glycoprotein
APCIGHGI_00836	5.59e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
APCIGHGI_00837	3.09e-30	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
APCIGHGI_00838	1e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
APCIGHGI_00839	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APCIGHGI_00840	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
APCIGHGI_00845	3.65e-259	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APCIGHGI_00846	1.91e-08	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APCIGHGI_00847	1.02e-210	-	-	-	L	-	-	-	Z1 domain
APCIGHGI_00848	4.16e-149	-	-	-	-	-	-	-	-
APCIGHGI_00849	6.2e-49	-	-	-	-	-	-	-	-
APCIGHGI_00850	2.11e-87	-	-	-	-	-	-	-	-
APCIGHGI_00852	9.64e-178	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
APCIGHGI_00853	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
APCIGHGI_00854	5.37e-72	-	-	-	S	-	-	-	MazG-like family
APCIGHGI_00855	5.35e-139	-	-	-	I	-	-	-	PAP2 superfamily
APCIGHGI_00856	1.01e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
APCIGHGI_00857	1.49e-125	-	-	-	-	-	-	-	-
APCIGHGI_00858	1.47e-286	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
APCIGHGI_00859	2.27e-218	-	-	-	V	-	-	-	Beta-lactamase enzyme family
APCIGHGI_00860	9.12e-30	potE	-	-	E	-	-	-	Amino Acid
APCIGHGI_00861	2.99e-298	potE	-	-	E	-	-	-	Amino Acid
APCIGHGI_00863	5.32e-142	-	-	-	-	-	-	-	-
APCIGHGI_00864	2.72e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
APCIGHGI_00865	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_00866	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
APCIGHGI_00867	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
APCIGHGI_00868	1.17e-249	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
APCIGHGI_00869	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APCIGHGI_00870	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APCIGHGI_00872	4.27e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
APCIGHGI_00873	1.12e-98	mleR	-	-	K	-	-	-	LysR family
APCIGHGI_00874	1.08e-289	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
APCIGHGI_00876	3.24e-225	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
APCIGHGI_00877	2.48e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APCIGHGI_00878	6.47e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APCIGHGI_00879	1.58e-270	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
APCIGHGI_00880	7.13e-288	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
APCIGHGI_00881	3.2e-209	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
APCIGHGI_00882	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
APCIGHGI_00883	2.42e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
APCIGHGI_00884	1.92e-241	-	-	-	I	-	-	-	Alpha beta
APCIGHGI_00885	7.04e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
APCIGHGI_00886	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APCIGHGI_00888	4.43e-219	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APCIGHGI_00889	1.24e-50	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
APCIGHGI_00890	6.32e-115	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
APCIGHGI_00891	6.72e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
APCIGHGI_00892	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APCIGHGI_00893	5.43e-94	-	-	-	K	-	-	-	MerR HTH family regulatory protein
APCIGHGI_00894	3.3e-77	-	-	-	-	-	-	-	-
APCIGHGI_00895	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APCIGHGI_00896	3.1e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APCIGHGI_00897	2.37e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
APCIGHGI_00898	5.87e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
APCIGHGI_00899	6.69e-142	-	-	-	S	-	-	-	VIT family
APCIGHGI_00900	9.24e-151	-	-	-	S	-	-	-	membrane
APCIGHGI_00901	8.8e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
APCIGHGI_00902	2.51e-158	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
APCIGHGI_00903	1.26e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APCIGHGI_00904	5.52e-161	-	-	-	S	-	-	-	Putative threonine/serine exporter
APCIGHGI_00905	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APCIGHGI_00906	2.57e-148	-	-	-	I	-	-	-	phosphatase
APCIGHGI_00907	1.4e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APCIGHGI_00909	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
APCIGHGI_00910	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
APCIGHGI_00916	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APCIGHGI_00917	1.77e-58	-	-	-	IQ	-	-	-	reductase
APCIGHGI_00918	2.91e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APCIGHGI_00919	5.67e-56	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
APCIGHGI_00921	1.49e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
APCIGHGI_00922	1.69e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
APCIGHGI_00923	1.37e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
APCIGHGI_00924	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
APCIGHGI_00925	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APCIGHGI_00926	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APCIGHGI_00927	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APCIGHGI_00928	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APCIGHGI_00929	1.19e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
APCIGHGI_00930	8.65e-275	-	-	-	-	-	-	-	-
APCIGHGI_00931	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
APCIGHGI_00932	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APCIGHGI_00933	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APCIGHGI_00934	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APCIGHGI_00935	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
APCIGHGI_00936	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APCIGHGI_00937	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
APCIGHGI_00938	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APCIGHGI_00939	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APCIGHGI_00940	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APCIGHGI_00941	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APCIGHGI_00942	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APCIGHGI_00943	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APCIGHGI_00944	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
APCIGHGI_00945	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APCIGHGI_00946	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APCIGHGI_00947	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APCIGHGI_00948	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APCIGHGI_00949	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APCIGHGI_00950	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APCIGHGI_00951	1.02e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APCIGHGI_00952	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APCIGHGI_00953	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APCIGHGI_00954	1.2e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
APCIGHGI_00955	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APCIGHGI_00956	1.36e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APCIGHGI_00957	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APCIGHGI_00958	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APCIGHGI_00959	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
APCIGHGI_00960	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APCIGHGI_00961	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APCIGHGI_00962	3.48e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APCIGHGI_00963	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
APCIGHGI_00964	1.75e-192	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APCIGHGI_00965	6.79e-98	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APCIGHGI_00966	5.49e-87	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APCIGHGI_00967	9.63e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APCIGHGI_00968	8.08e-188	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APCIGHGI_00969	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APCIGHGI_00970	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
APCIGHGI_00971	3.44e-173	-	-	-	S	-	-	-	interspecies interaction between organisms
APCIGHGI_00972	2.68e-70	-	-	-	S	-	-	-	interspecies interaction between organisms
APCIGHGI_00973	8.64e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
APCIGHGI_00974	1.35e-141	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
APCIGHGI_00975	2.25e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APCIGHGI_00976	7.16e-278	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APCIGHGI_00977	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
APCIGHGI_00978	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APCIGHGI_00979	7.07e-236	camS	-	-	S	-	-	-	sex pheromone
APCIGHGI_00980	9.93e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APCIGHGI_00981	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APCIGHGI_00982	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APCIGHGI_00983	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
APCIGHGI_00984	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APCIGHGI_00985	2.14e-88	-	-	-	S	-	-	-	Abortive infection C-terminus
APCIGHGI_00986	7.9e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00987	1.03e-46	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_00988	2e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_00989	3.3e-105	-	-	-	-	-	-	-	-
APCIGHGI_00990	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APCIGHGI_00991	2.45e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
APCIGHGI_00992	1.11e-59	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
APCIGHGI_00993	1.5e-144	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
APCIGHGI_00994	7.9e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_00995	7.58e-192	is18	-	-	L	-	-	-	Integrase core domain
APCIGHGI_00997	2.98e-94	-	-	-	S	-	-	-	Protease prsW family
APCIGHGI_00998	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
APCIGHGI_00999	1.74e-214	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
APCIGHGI_01001	2.19e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
APCIGHGI_01002	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
APCIGHGI_01003	9.21e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
APCIGHGI_01004	3.69e-31	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
APCIGHGI_01005	1.23e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APCIGHGI_01009	6.49e-182	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
APCIGHGI_01010	2.51e-246	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
APCIGHGI_01012	1.87e-95	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
APCIGHGI_01013	5.51e-116	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
APCIGHGI_01014	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
APCIGHGI_01015	2.47e-68	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
APCIGHGI_01016	1.03e-120	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
APCIGHGI_01017	4.1e-153	-	-	-	Q	-	-	-	Methyltransferase domain
APCIGHGI_01019	5.52e-133	-	-	-	S	-	-	-	CAAX protease self-immunity
APCIGHGI_01020	3.59e-128	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APCIGHGI_01021	5.38e-58	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APCIGHGI_01022	8.91e-29	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APCIGHGI_01023	5.24e-39	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APCIGHGI_01024	5.65e-130	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APCIGHGI_01025	2.79e-276	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APCIGHGI_01026	2.2e-136	-	-	-	-	-	-	-	-
APCIGHGI_01027	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
APCIGHGI_01028	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
APCIGHGI_01029	2.89e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
APCIGHGI_01030	2.48e-178	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APCIGHGI_01031	4.72e-96	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
APCIGHGI_01032	1.33e-206	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
APCIGHGI_01033	6.14e-204	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APCIGHGI_01034	1.04e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
APCIGHGI_01035	2.11e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
APCIGHGI_01036	4.94e-244	mocA	-	-	S	-	-	-	Oxidoreductase
APCIGHGI_01037	1.42e-305	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
APCIGHGI_01039	6.8e-316	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_01040	8.87e-245	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
APCIGHGI_01041	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
APCIGHGI_01042	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
APCIGHGI_01043	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
APCIGHGI_01044	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
APCIGHGI_01045	1.01e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
APCIGHGI_01046	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
APCIGHGI_01048	2.05e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
APCIGHGI_01049	1.73e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
APCIGHGI_01050	1.71e-191	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
APCIGHGI_01051	4.76e-117	cps3F	-	-	-	-	-	-	-
APCIGHGI_01052	5.36e-39	-	-	-	M	-	-	-	biosynthesis protein
APCIGHGI_01053	1.03e-60	cps3I	-	-	G	-	-	-	Acyltransferase family
APCIGHGI_01054	5.66e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
APCIGHGI_01055	1.88e-254	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
APCIGHGI_01057	5e-22	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
APCIGHGI_01058	2.88e-277	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01059	3.47e-72	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APCIGHGI_01060	4.51e-113	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
APCIGHGI_01061	1.55e-09	-	-	-	-	-	-	-	-
APCIGHGI_01062	4.64e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
APCIGHGI_01063	2.66e-212	yueF	-	-	S	-	-	-	AI-2E family transporter
APCIGHGI_01064	1.74e-209	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
APCIGHGI_01065	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APCIGHGI_01066	3.71e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
APCIGHGI_01067	2.11e-126	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
APCIGHGI_01068	3.11e-100	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
APCIGHGI_01069	1.08e-218	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APCIGHGI_01070	8.46e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
APCIGHGI_01071	5.71e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01073	1.38e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
APCIGHGI_01074	4.44e-208	-	-	-	EG	-	-	-	EamA-like transporter family
APCIGHGI_01075	4.96e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APCIGHGI_01076	6.68e-182	-	-	-	G	-	-	-	MucBP domain
APCIGHGI_01077	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
APCIGHGI_01078	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APCIGHGI_01079	8.61e-143	pncA	-	-	Q	-	-	-	Isochorismatase family
APCIGHGI_01080	8.69e-167	-	-	-	F	-	-	-	NUDIX domain
APCIGHGI_01081	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
APCIGHGI_01082	2.41e-07	-	-	-	-	-	-	-	-
APCIGHGI_01083	8.72e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
APCIGHGI_01084	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APCIGHGI_01085	6.56e-293	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APCIGHGI_01086	2.58e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APCIGHGI_01087	9.75e-232	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APCIGHGI_01088	2.81e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
APCIGHGI_01091	8.34e-101	-	-	-	-	-	-	-	-
APCIGHGI_01101	6.22e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01103	8.21e-07	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_01104	8.27e-184	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
APCIGHGI_01105	5.28e-144	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APCIGHGI_01106	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
APCIGHGI_01107	2.99e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APCIGHGI_01108	1.03e-206	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
APCIGHGI_01109	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
APCIGHGI_01110	2.88e-254	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
APCIGHGI_01111	2.21e-90	-	-	-	M	-	-	-	LysM domain protein
APCIGHGI_01112	7.27e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
APCIGHGI_01113	5.41e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
APCIGHGI_01114	1.05e-70	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
APCIGHGI_01115	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01116	2.37e-50	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01117	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_01118	1.82e-235	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01121	3.91e-31	-	-	-	-	-	-	-	-
APCIGHGI_01122	6.39e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
APCIGHGI_01123	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
APCIGHGI_01124	0.0	-	-	-	EGP	-	-	-	Major Facilitator
APCIGHGI_01125	1.1e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
APCIGHGI_01126	3.23e-64	-	-	-	-	-	-	-	-
APCIGHGI_01127	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APCIGHGI_01128	2.19e-179	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APCIGHGI_01129	4.39e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APCIGHGI_01130	2.93e-163	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
APCIGHGI_01131	9.93e-305	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01132	3.88e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01133	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
APCIGHGI_01134	9.88e-57	-	-	-	-	-	-	-	-
APCIGHGI_01135	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
APCIGHGI_01136	3.31e-81	-	-	-	S	-	-	-	Domain of unknown function DUF302
APCIGHGI_01137	1.14e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APCIGHGI_01138	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
APCIGHGI_01139	2.01e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
APCIGHGI_01140	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
APCIGHGI_01141	1.33e-239	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APCIGHGI_01142	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
APCIGHGI_01143	9.92e-143	-	-	-	-	-	-	-	-
APCIGHGI_01144	6.39e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
APCIGHGI_01145	4.99e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APCIGHGI_01146	9.96e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APCIGHGI_01147	1.25e-119	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
APCIGHGI_01148	3.93e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
APCIGHGI_01149	1.43e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
APCIGHGI_01150	7.88e-137	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
APCIGHGI_01151	4.42e-259	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
APCIGHGI_01153	4.86e-53	-	-	-	-	-	-	-	-
APCIGHGI_01155	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
APCIGHGI_01156	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
APCIGHGI_01157	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
APCIGHGI_01158	1.23e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
APCIGHGI_01159	6.67e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APCIGHGI_01161	1.23e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
APCIGHGI_01162	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01163	2.21e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APCIGHGI_01164	3.88e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APCIGHGI_01165	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
APCIGHGI_01166	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
APCIGHGI_01167	1.11e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APCIGHGI_01168	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
APCIGHGI_01169	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
APCIGHGI_01170	1.03e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01171	1.4e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
APCIGHGI_01172	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APCIGHGI_01173	3.08e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APCIGHGI_01174	4.15e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APCIGHGI_01175	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APCIGHGI_01176	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
APCIGHGI_01177	4.41e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
APCIGHGI_01178	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APCIGHGI_01179	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
APCIGHGI_01180	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APCIGHGI_01181	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
APCIGHGI_01182	7.57e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
APCIGHGI_01183	1.69e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
APCIGHGI_01184	2.29e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
APCIGHGI_01185	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
APCIGHGI_01186	1.62e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APCIGHGI_01187	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
APCIGHGI_01188	1.96e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APCIGHGI_01189	7.76e-182	yqeM	-	-	Q	-	-	-	Methyltransferase
APCIGHGI_01190	2.38e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
APCIGHGI_01191	2.79e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
APCIGHGI_01192	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
APCIGHGI_01193	1.38e-155	csrR	-	-	K	-	-	-	response regulator
APCIGHGI_01194	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APCIGHGI_01195	1.88e-298	-	-	-	V	-	-	-	MatE
APCIGHGI_01196	5.31e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
APCIGHGI_01197	1.18e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APCIGHGI_01198	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
APCIGHGI_01199	7.49e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APCIGHGI_01200	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APCIGHGI_01201	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APCIGHGI_01202	4.27e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APCIGHGI_01203	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APCIGHGI_01204	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
APCIGHGI_01205	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APCIGHGI_01206	0.0	-	-	-	S	-	-	-	membrane
APCIGHGI_01207	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APCIGHGI_01208	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APCIGHGI_01209	3.66e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APCIGHGI_01210	1.04e-135	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
APCIGHGI_01211	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
APCIGHGI_01212	5.87e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
APCIGHGI_01213	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
APCIGHGI_01214	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
APCIGHGI_01215	1.27e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APCIGHGI_01216	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
APCIGHGI_01217	4.76e-19	-	-	-	-	-	-	-	-
APCIGHGI_01218	1.9e-201	-	-	-	-	-	-	-	-
APCIGHGI_01219	2.34e-226	-	-	-	-	-	-	-	-
APCIGHGI_01220	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
APCIGHGI_01222	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_01223	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
APCIGHGI_01224	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
APCIGHGI_01225	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
APCIGHGI_01226	3.44e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APCIGHGI_01227	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
APCIGHGI_01228	8.07e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APCIGHGI_01229	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APCIGHGI_01230	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APCIGHGI_01231	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APCIGHGI_01232	2.93e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APCIGHGI_01233	3.62e-55	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
APCIGHGI_01234	1.69e-117	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
APCIGHGI_01235	2.85e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APCIGHGI_01236	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
APCIGHGI_01238	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
APCIGHGI_01239	1.9e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APCIGHGI_01240	2.07e-282	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APCIGHGI_01241	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APCIGHGI_01242	5.61e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APCIGHGI_01243	5.57e-316	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APCIGHGI_01244	1.68e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
APCIGHGI_01245	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
APCIGHGI_01246	1.78e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APCIGHGI_01247	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
APCIGHGI_01248	2.05e-46	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
APCIGHGI_01249	8e-75	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
APCIGHGI_01250	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
APCIGHGI_01251	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APCIGHGI_01252	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
APCIGHGI_01253	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APCIGHGI_01254	2.2e-215	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APCIGHGI_01255	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APCIGHGI_01256	3.99e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APCIGHGI_01257	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
APCIGHGI_01258	9.65e-295	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APCIGHGI_01259	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APCIGHGI_01260	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APCIGHGI_01262	4.48e-52	-	-	-	-	-	-	-	-
APCIGHGI_01263	1.41e-40	-	-	-	-	-	-	-	-
APCIGHGI_01264	1.62e-166	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
APCIGHGI_01265	3.16e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
APCIGHGI_01266	1.95e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
APCIGHGI_01267	4.99e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
APCIGHGI_01268	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APCIGHGI_01269	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
APCIGHGI_01270	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
APCIGHGI_01271	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
APCIGHGI_01272	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APCIGHGI_01273	1.83e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
APCIGHGI_01274	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
APCIGHGI_01275	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APCIGHGI_01276	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
APCIGHGI_01277	1.94e-188	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
APCIGHGI_01278	1.59e-51	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
APCIGHGI_01279	1.91e-164	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
APCIGHGI_01280	4.04e-82	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
APCIGHGI_01281	9.63e-90	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
APCIGHGI_01282	2.53e-159	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APCIGHGI_01283	1.81e-101	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
APCIGHGI_01287	3.52e-50	-	-	-	-	-	-	-	-
APCIGHGI_01288	6.37e-92	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_01289	1.35e-238	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
APCIGHGI_01290	1.08e-92	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APCIGHGI_01291	4.98e-311	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APCIGHGI_01294	1.58e-07	-	-	-	-	-	-	-	-
APCIGHGI_01296	3.02e-23	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
APCIGHGI_01297	3.97e-10	-	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APCIGHGI_01299	3.56e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_01300	1.51e-152	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APCIGHGI_01302	6.11e-143	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
APCIGHGI_01303	1.14e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
APCIGHGI_01304	3.97e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APCIGHGI_01305	2.95e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
APCIGHGI_01306	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
APCIGHGI_01307	2.75e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APCIGHGI_01308	5.29e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
APCIGHGI_01309	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
APCIGHGI_01310	1.12e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01311	1.61e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01312	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APCIGHGI_01313	1e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
APCIGHGI_01314	3.68e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
APCIGHGI_01315	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
APCIGHGI_01316	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
APCIGHGI_01317	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
APCIGHGI_01318	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
APCIGHGI_01319	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
APCIGHGI_01320	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
APCIGHGI_01321	1.65e-243	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
APCIGHGI_01322	6.64e-205	-	-	-	EG	-	-	-	EamA-like transporter family
APCIGHGI_01323	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
APCIGHGI_01324	2.08e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APCIGHGI_01325	1.79e-143	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
APCIGHGI_01326	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APCIGHGI_01327	0.0	fusA1	-	-	J	-	-	-	elongation factor G
APCIGHGI_01328	8.81e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
APCIGHGI_01329	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
APCIGHGI_01330	4.48e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
APCIGHGI_01331	1.81e-160	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
APCIGHGI_01332	4.54e-118	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
APCIGHGI_01333	8.87e-40	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
APCIGHGI_01334	1.36e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
APCIGHGI_01335	3.77e-93	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
APCIGHGI_01336	3.5e-92	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
APCIGHGI_01337	1.48e-98	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APCIGHGI_01338	4.45e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APCIGHGI_01339	8.46e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
APCIGHGI_01340	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
APCIGHGI_01341	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
APCIGHGI_01342	1.22e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
APCIGHGI_01343	1.08e-29	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
APCIGHGI_01344	5.63e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01345	6.71e-06	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01346	4.55e-74	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
APCIGHGI_01347	6.89e-235	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
APCIGHGI_01348	2.94e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APCIGHGI_01349	5.59e-290	-	-	-	L	-	-	-	MULE transposase domain
APCIGHGI_01350	2.72e-124	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_01351	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
APCIGHGI_01352	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
APCIGHGI_01353	4.63e-128	-	-	-	-	-	-	-	-
APCIGHGI_01354	6.09e-173	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
APCIGHGI_01355	2.5e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APCIGHGI_01356	1.24e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
APCIGHGI_01357	8.44e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APCIGHGI_01358	5.71e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APCIGHGI_01359	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
APCIGHGI_01360	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
APCIGHGI_01361	1.99e-157	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
APCIGHGI_01362	8.74e-69	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
APCIGHGI_01363	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
APCIGHGI_01364	4.9e-232	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
APCIGHGI_01365	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
APCIGHGI_01366	2.02e-274	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APCIGHGI_01367	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
APCIGHGI_01368	2.03e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
APCIGHGI_01369	1.67e-272	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
APCIGHGI_01370	1.31e-123	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
APCIGHGI_01371	9.73e-276	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
APCIGHGI_01372	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
APCIGHGI_01373	1.8e-271	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
APCIGHGI_01374	3.23e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
APCIGHGI_01375	8.85e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APCIGHGI_01376	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APCIGHGI_01377	2.36e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APCIGHGI_01378	3.07e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APCIGHGI_01379	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APCIGHGI_01380	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
APCIGHGI_01381	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
APCIGHGI_01382	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APCIGHGI_01384	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
APCIGHGI_01385	1.65e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01386	3.87e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01387	1.15e-42	-	-	-	-	-	-	-	-
APCIGHGI_01388	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
APCIGHGI_01390	2.78e-301	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
APCIGHGI_01391	1.71e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
APCIGHGI_01392	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_01393	5.51e-205	-	-	-	GM	-	-	-	NAD(P)H-binding
APCIGHGI_01394	5.27e-195	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APCIGHGI_01397	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
APCIGHGI_01398	3.51e-273	-	-	-	G	-	-	-	Major Facilitator Superfamily
APCIGHGI_01399	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
APCIGHGI_01400	4.62e-273	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APCIGHGI_01401	9.4e-133	-	-	-	-	-	-	-	-
APCIGHGI_01402	3.72e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APCIGHGI_01403	3.37e-250	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
APCIGHGI_01404	1.51e-116	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APCIGHGI_01405	1.5e-277	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
APCIGHGI_01406	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_01407	3.65e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APCIGHGI_01408	1.1e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
APCIGHGI_01409	1.65e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01410	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
APCIGHGI_01411	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
APCIGHGI_01412	9.57e-44	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
APCIGHGI_01413	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
APCIGHGI_01414	6.06e-309	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
APCIGHGI_01415	1.02e-295	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APCIGHGI_01416	1.45e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
APCIGHGI_01417	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
APCIGHGI_01418	3.47e-244	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
APCIGHGI_01419	8.87e-245	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
APCIGHGI_01420	1.12e-181	-	-	-	EG	-	-	-	EamA-like transporter family
APCIGHGI_01421	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
APCIGHGI_01422	4.24e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
APCIGHGI_01423	3.62e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
APCIGHGI_01424	2.99e-290	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
APCIGHGI_01425	1.03e-149	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APCIGHGI_01426	1.78e-219	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APCIGHGI_01427	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
APCIGHGI_01428	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
APCIGHGI_01429	4.09e-250	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APCIGHGI_01430	2.7e-277	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
APCIGHGI_01431	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
APCIGHGI_01432	5.52e-209	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
APCIGHGI_01433	7.17e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APCIGHGI_01434	1.76e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01435	5.31e-72	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01436	1.61e-12	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
APCIGHGI_01437	1.69e-124	-	-	-	V	-	-	-	VanZ like family
APCIGHGI_01438	2.95e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
APCIGHGI_01439	2.74e-81	-	-	-	-	-	-	-	-
APCIGHGI_01440	1.98e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_01441	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
APCIGHGI_01442	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
APCIGHGI_01443	1.17e-219	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
APCIGHGI_01444	3.29e-74	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
APCIGHGI_01446	1.03e-106	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
APCIGHGI_01447	2.27e-54	-	-	-	-	-	-	-	-
APCIGHGI_01448	4.07e-216	-	-	-	GK	-	-	-	ROK family
APCIGHGI_01449	1.44e-164	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
APCIGHGI_01450	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
APCIGHGI_01451	2.68e-134	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
APCIGHGI_01452	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APCIGHGI_01453	1.73e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APCIGHGI_01454	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APCIGHGI_01455	3.04e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
APCIGHGI_01456	6.32e-97	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
APCIGHGI_01457	1.02e-129	-	-	-	K	-	-	-	DNA-templated transcription, initiation
APCIGHGI_01459	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
APCIGHGI_01460	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
APCIGHGI_01461	6.4e-149	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01462	1.72e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
APCIGHGI_01463	2.02e-146	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
APCIGHGI_01464	3.81e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
APCIGHGI_01465	4.63e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APCIGHGI_01466	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
APCIGHGI_01467	5.19e-48	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
APCIGHGI_01468	9.13e-130	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
APCIGHGI_01469	5.61e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
APCIGHGI_01470	2.42e-43	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
APCIGHGI_01471	4.5e-112	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
APCIGHGI_01472	9.85e-53	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
APCIGHGI_01473	1.06e-300	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
APCIGHGI_01475	3.18e-211	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01476	2.78e-120	-	-	-	L	-	-	-	Bacterial dnaA protein
APCIGHGI_01477	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
APCIGHGI_01478	1.52e-82	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APCIGHGI_01479	4.76e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01480	3.79e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01481	2.73e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_01482	1.41e-286	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
APCIGHGI_01483	3.86e-197	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
APCIGHGI_01484	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
APCIGHGI_01485	2.75e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01486	1.79e-290	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01487	3.57e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01489	8.99e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
APCIGHGI_01491	2.66e-122	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
APCIGHGI_01492	5.05e-128	-	-	-	K	-	-	-	Virulence activator alpha C-term
APCIGHGI_01493	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
APCIGHGI_01494	1.08e-39	-	-	-	S	-	-	-	SNARE associated Golgi protein
APCIGHGI_01495	4.29e-17	-	-	-	S	-	-	-	SNARE associated Golgi protein
APCIGHGI_01496	2.24e-303	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
APCIGHGI_01497	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APCIGHGI_01499	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
APCIGHGI_01500	8.84e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01502	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APCIGHGI_01503	1.58e-208	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
APCIGHGI_01504	1.41e-211	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
APCIGHGI_01505	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APCIGHGI_01506	5.3e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APCIGHGI_01508	1.13e-290	-	-	-	-	-	-	-	-
APCIGHGI_01509	4.78e-249	flp	-	-	V	-	-	-	Beta-lactamase
APCIGHGI_01510	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
APCIGHGI_01511	8.47e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APCIGHGI_01512	5.43e-238	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
APCIGHGI_01513	1.33e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
APCIGHGI_01514	3.46e-207	rssA	-	-	S	-	-	-	Phospholipase, patatin family
APCIGHGI_01515	6.5e-144	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_01516	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
APCIGHGI_01517	4.39e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
APCIGHGI_01518	8.21e-144	yicL	-	-	EG	-	-	-	EamA-like transporter family
APCIGHGI_01519	1.94e-86	-	-	-	-	-	-	-	-
APCIGHGI_01521	6.22e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01523	7.49e-47	-	-	-	-	-	-	-	-
APCIGHGI_01524	4.63e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
APCIGHGI_01525	2.98e-227	-	-	-	K	-	-	-	WYL domain
APCIGHGI_01526	3.48e-306	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
APCIGHGI_01527	1.3e-47	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
APCIGHGI_01528	5.78e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APCIGHGI_01529	2.65e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
APCIGHGI_01530	2.45e-94	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01531	1.98e-56	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01532	5.2e-143	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_01533	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_01534	7.15e-277	-	-	-	G	-	-	-	Transporter, major facilitator family protein
APCIGHGI_01535	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APCIGHGI_01536	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APCIGHGI_01537	7.78e-74	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
APCIGHGI_01538	6.51e-45	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
APCIGHGI_01539	5.73e-77	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APCIGHGI_01540	3.22e-233	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APCIGHGI_01541	2.13e-114	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APCIGHGI_01542	7.91e-280	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APCIGHGI_01543	9.37e-206	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APCIGHGI_01545	1.31e-210	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
APCIGHGI_01546	8.33e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
APCIGHGI_01547	6.16e-225	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
APCIGHGI_01548	3.57e-136	citR	-	-	K	-	-	-	sugar-binding domain protein
APCIGHGI_01549	1.08e-189	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
APCIGHGI_01550	2.81e-139	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
APCIGHGI_01551	4.37e-111	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APCIGHGI_01552	2.55e-47	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
APCIGHGI_01553	4.82e-185	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
APCIGHGI_01554	1.04e-302	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
APCIGHGI_01556	1.36e-94	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
APCIGHGI_01557	4.31e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
APCIGHGI_01558	6.26e-138	-	-	-	L	-	-	-	Integrase
APCIGHGI_01559	4.58e-59	-	-	-	K	-	-	-	transcriptional regulator
APCIGHGI_01560	9.43e-85	-	-	-	GM	-	-	-	NmrA-like family
APCIGHGI_01561	2.66e-33	-	-	-	C	-	-	-	Flavodoxin
APCIGHGI_01562	8.2e-14	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
APCIGHGI_01563	4.74e-69	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
APCIGHGI_01564	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
APCIGHGI_01565	1.21e-99	ywnA	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_01566	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
APCIGHGI_01567	1.8e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APCIGHGI_01568	3.82e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01569	7.62e-130	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
APCIGHGI_01570	1.39e-246	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
APCIGHGI_01571	2.75e-184	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
APCIGHGI_01572	2.03e-250	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
APCIGHGI_01573	1.41e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
APCIGHGI_01574	1.39e-229	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APCIGHGI_01575	6.9e-258	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
APCIGHGI_01576	1.08e-78	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
APCIGHGI_01577	6.35e-279	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
APCIGHGI_01578	4.49e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
APCIGHGI_01579	1.85e-105	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
APCIGHGI_01580	4.84e-215	yvgN	-	-	C	-	-	-	Aldo keto reductase
APCIGHGI_01581	5.05e-207	-	-	-	S	-	-	-	DUF218 domain
APCIGHGI_01583	1.41e-06	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
APCIGHGI_01584	3.42e-109	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APCIGHGI_01585	2.7e-39	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APCIGHGI_01586	2.42e-154	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APCIGHGI_01587	8.38e-92	-	-	-	S	-	-	-	Phage minor capsid protein 2
APCIGHGI_01588	2.21e-40	-	-	-	S	-	-	-	Phage minor capsid protein 2
APCIGHGI_01591	2.21e-275	-	-	-	E	-	-	-	Aminotransferase
APCIGHGI_01592	1.36e-134	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
APCIGHGI_01593	4.26e-89	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
APCIGHGI_01594	0.0	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
APCIGHGI_01595	8.93e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
APCIGHGI_01596	4.41e-110	-	-	-	S	-	-	-	Fic/DOC family
APCIGHGI_01597	4.24e-119	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
APCIGHGI_01598	2.04e-128	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
APCIGHGI_01599	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
APCIGHGI_01600	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
APCIGHGI_01601	5.85e-166	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APCIGHGI_01602	1.02e-153	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
APCIGHGI_01603	1.29e-196	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
APCIGHGI_01604	3.82e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APCIGHGI_01605	2.74e-82	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APCIGHGI_01606	9.63e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APCIGHGI_01608	4.11e-310	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
APCIGHGI_01609	3.8e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
APCIGHGI_01610	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APCIGHGI_01612	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
APCIGHGI_01613	1.53e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
APCIGHGI_01614	2.4e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
APCIGHGI_01615	4.02e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
APCIGHGI_01616	3.6e-122	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
APCIGHGI_01617	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
APCIGHGI_01618	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
APCIGHGI_01619	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
APCIGHGI_01620	1.46e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
APCIGHGI_01621	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APCIGHGI_01622	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APCIGHGI_01623	5.26e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APCIGHGI_01624	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
APCIGHGI_01625	3.55e-195	-	-	-	D	-	-	-	DNA integration
APCIGHGI_01626	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APCIGHGI_01627	6.25e-213	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
APCIGHGI_01628	5.03e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APCIGHGI_01629	1.03e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APCIGHGI_01630	1.21e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
APCIGHGI_01631	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
APCIGHGI_01632	2.46e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
APCIGHGI_01633	4.69e-144	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
APCIGHGI_01634	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
APCIGHGI_01635	4.49e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
APCIGHGI_01636	8.06e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
APCIGHGI_01637	4.4e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APCIGHGI_01638	3.08e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APCIGHGI_01639	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01640	3.59e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APCIGHGI_01641	1.29e-211	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
APCIGHGI_01642	2.52e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
APCIGHGI_01643	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APCIGHGI_01644	4.3e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
APCIGHGI_01645	8.93e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
APCIGHGI_01646	5.63e-154	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
APCIGHGI_01647	4.37e-76	-	-	-	M	-	-	-	Lysin motif
APCIGHGI_01648	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APCIGHGI_01649	1.34e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
APCIGHGI_01650	2.03e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APCIGHGI_01651	1.44e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APCIGHGI_01652	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APCIGHGI_01653	1.18e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APCIGHGI_01654	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APCIGHGI_01655	1.21e-174	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
APCIGHGI_01656	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
APCIGHGI_01657	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
APCIGHGI_01658	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
APCIGHGI_01660	2.52e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
APCIGHGI_01661	1.2e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APCIGHGI_01662	2.3e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
APCIGHGI_01663	5.64e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
APCIGHGI_01664	8.31e-294	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
APCIGHGI_01665	1.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APCIGHGI_01666	1.14e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APCIGHGI_01667	4.65e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APCIGHGI_01668	1.27e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APCIGHGI_01669	1.15e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APCIGHGI_01670	6.39e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APCIGHGI_01671	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APCIGHGI_01672	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APCIGHGI_01673	8.7e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APCIGHGI_01674	1.93e-213	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APCIGHGI_01675	2.56e-157	-	-	-	EGP	-	-	-	Major Facilitator
APCIGHGI_01676	1.12e-127	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
APCIGHGI_01677	8.84e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01678	1.21e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APCIGHGI_01679	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APCIGHGI_01680	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
APCIGHGI_01681	4.19e-239	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
APCIGHGI_01682	7.52e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
APCIGHGI_01683	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APCIGHGI_01684	6.28e-87	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
APCIGHGI_01685	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APCIGHGI_01686	3.02e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
APCIGHGI_01687	1.25e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
APCIGHGI_01688	1.56e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
APCIGHGI_01689	1.1e-165	-	-	-	F	-	-	-	glutamine amidotransferase
APCIGHGI_01690	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APCIGHGI_01691	1.39e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
APCIGHGI_01692	6.29e-250	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
APCIGHGI_01693	5.18e-225	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
APCIGHGI_01694	7.92e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
APCIGHGI_01695	2.38e-222	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
APCIGHGI_01696	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
APCIGHGI_01697	2.34e-204	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
APCIGHGI_01698	4.76e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
APCIGHGI_01699	4.47e-175	-	-	-	IQ	-	-	-	KR domain
APCIGHGI_01700	7.45e-197	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
APCIGHGI_01701	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01702	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
APCIGHGI_01703	1.96e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
APCIGHGI_01705	1.53e-108	-	-	-	S	-	-	-	MmgE/PrpD family
APCIGHGI_01706	2.55e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
APCIGHGI_01707	8.5e-185	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
APCIGHGI_01708	2.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
APCIGHGI_01709	6.91e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
APCIGHGI_01710	2.07e-59	yxeL	-	-	K	-	-	-	acetyltransferase
APCIGHGI_01711	6.31e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
APCIGHGI_01713	1.87e-270	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
APCIGHGI_01714	4e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
APCIGHGI_01715	9.22e-53	-	-	-	K	-	-	-	Transcriptional regulator
APCIGHGI_01716	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APCIGHGI_01717	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APCIGHGI_01718	4.23e-76	-	-	-	-	-	-	-	-
APCIGHGI_01719	6.09e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APCIGHGI_01720	3.69e-231	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
APCIGHGI_01721	4.82e-72	-	-	-	-	-	-	-	-
APCIGHGI_01722	4.72e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01723	1.65e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01725	5.81e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
APCIGHGI_01726	1.81e-122	-	-	-	S	-	-	-	integral membrane protein
APCIGHGI_01728	5.33e-41	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
APCIGHGI_01729	7.1e-100	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
APCIGHGI_01730	2.96e-117	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_01731	1.02e-71	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
APCIGHGI_01732	8.75e-96	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
APCIGHGI_01733	4.83e-245	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Major facilitator superfamily
APCIGHGI_01735	6.69e-43	-	-	-	I	ko:K01066	-	ko00000,ko01000	Esterase lipase
APCIGHGI_01736	2.38e-42	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
APCIGHGI_01738	1.34e-42	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
APCIGHGI_01739	2.93e-47	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APCIGHGI_01740	8.7e-116	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APCIGHGI_01741	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
APCIGHGI_01742	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APCIGHGI_01743	1.01e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APCIGHGI_01744	2.21e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APCIGHGI_01745	6.14e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APCIGHGI_01746	6.81e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APCIGHGI_01747	2.94e-89	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
APCIGHGI_01748	9.63e-51	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
APCIGHGI_01749	1.67e-268	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
APCIGHGI_01750	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
APCIGHGI_01751	4.7e-242	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
APCIGHGI_01752	2.01e-05	-	-	-	K	-	-	-	LysR substrate binding domain
APCIGHGI_01753	1.3e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APCIGHGI_01754	1.99e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APCIGHGI_01755	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APCIGHGI_01756	4.44e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
APCIGHGI_01757	3.14e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
APCIGHGI_01758	1.35e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01759	4.21e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01761	1.29e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
APCIGHGI_01762	4.41e-14	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
APCIGHGI_01763	2.06e-66	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APCIGHGI_01765	2.43e-51	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
APCIGHGI_01766	1.42e-70	-	-	-	C	-	-	-	FMN binding
APCIGHGI_01767	4.86e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APCIGHGI_01768	1.84e-138	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
APCIGHGI_01769	7.91e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
APCIGHGI_01770	1.97e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APCIGHGI_01771	9.59e-104	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
APCIGHGI_01772	0.0	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
APCIGHGI_01773	2.52e-283	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_01774	5.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APCIGHGI_01775	6.36e-138	-	-	-	C	-	-	-	aldo keto reductase
APCIGHGI_01776	9.14e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
APCIGHGI_01778	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APCIGHGI_01779	1.56e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APCIGHGI_01780	2.63e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
APCIGHGI_01781	1.12e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
APCIGHGI_01782	5.43e-183	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APCIGHGI_01783	1.96e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APCIGHGI_01784	3.46e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APCIGHGI_01785	7.58e-134	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
APCIGHGI_01786	1.56e-293	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APCIGHGI_01787	3.18e-140	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APCIGHGI_01788	4.3e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APCIGHGI_01789	2.55e-215	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
APCIGHGI_01790	3.33e-63	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APCIGHGI_01791	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APCIGHGI_01792	1.86e-122	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APCIGHGI_01793	9.95e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APCIGHGI_01794	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
APCIGHGI_01795	1.08e-90	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APCIGHGI_01796	1.26e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APCIGHGI_01797	5.73e-82	-	-	-	-	-	-	-	-
APCIGHGI_01798	2.56e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
APCIGHGI_01799	2.04e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
APCIGHGI_01800	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
APCIGHGI_01801	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
APCIGHGI_01802	8.84e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01803	1.64e-121	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
APCIGHGI_01804	1.02e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
APCIGHGI_01805	2.84e-240	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APCIGHGI_01806	1.16e-75	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01807	2.96e-82	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01808	1.53e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
APCIGHGI_01810	1.9e-85	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
APCIGHGI_01811	1.89e-228	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_01812	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APCIGHGI_01813	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
APCIGHGI_01814	3.85e-198	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
APCIGHGI_01815	4.15e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
APCIGHGI_01816	1.12e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01817	9e-317	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APCIGHGI_01818	2.15e-235	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
APCIGHGI_01819	5.34e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APCIGHGI_01820	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APCIGHGI_01821	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APCIGHGI_01822	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
APCIGHGI_01823	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
APCIGHGI_01824	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
APCIGHGI_01825	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
APCIGHGI_01826	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
APCIGHGI_01827	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
APCIGHGI_01828	3.37e-249	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APCIGHGI_01829	3e-265	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APCIGHGI_01830	4.83e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
APCIGHGI_01831	6.58e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
APCIGHGI_01832	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APCIGHGI_01833	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APCIGHGI_01834	3.56e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
APCIGHGI_01835	8.21e-174	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
APCIGHGI_01836	2.7e-185	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APCIGHGI_01837	6.51e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APCIGHGI_01838	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
APCIGHGI_01839	4.14e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APCIGHGI_01840	3.14e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
APCIGHGI_01841	2.67e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
APCIGHGI_01842	6.86e-176	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
APCIGHGI_01843	3.06e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
APCIGHGI_01844	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
APCIGHGI_01845	5.66e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
APCIGHGI_01846	4.36e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APCIGHGI_01847	2.21e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
APCIGHGI_01848	2.76e-155	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
APCIGHGI_01849	1.52e-307	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
APCIGHGI_01850	5.56e-110	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
APCIGHGI_01851	8.63e-18	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
APCIGHGI_01852	1.75e-10	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
APCIGHGI_01853	1.86e-66	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
APCIGHGI_01854	3.02e-35	yitW	-	-	S	-	-	-	DNA methyltransferase
APCIGHGI_01855	8.84e-141	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APCIGHGI_01856	1.15e-82	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
APCIGHGI_01859	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01860	1.34e-218	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01861	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APCIGHGI_01862	9.37e-315	-	-	-	G	-	-	-	Major Facilitator Superfamily
APCIGHGI_01863	1.78e-242	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
APCIGHGI_01865	4.52e-126	-	-	-	-	-	-	-	-
APCIGHGI_01866	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
APCIGHGI_01867	5.69e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
APCIGHGI_01869	8.44e-20	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
APCIGHGI_01872	1.73e-17	-	-	-	S	-	-	-	CHY zinc finger
APCIGHGI_01874	4.76e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01875	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
APCIGHGI_01877	2.73e-244	-	-	-	EGP	-	-	-	Major Facilitator
APCIGHGI_01880	6.48e-54	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01882	6.09e-254	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
APCIGHGI_01883	3.49e-13	-	-	-	K	-	-	-	transcriptional
APCIGHGI_01884	1.75e-46	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
APCIGHGI_01885	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APCIGHGI_01886	8.36e-59	-	-	-	S	-	-	-	Protein conserved in bacteria
APCIGHGI_01887	1.29e-124	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
APCIGHGI_01888	1.78e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01889	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01890	3.71e-194	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
APCIGHGI_01891	1.11e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APCIGHGI_01892	1.64e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
APCIGHGI_01893	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APCIGHGI_01894	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
APCIGHGI_01895	3.71e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
APCIGHGI_01896	7.1e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APCIGHGI_01897	9.56e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APCIGHGI_01898	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APCIGHGI_01899	3.97e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APCIGHGI_01901	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
APCIGHGI_01902	5.34e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
APCIGHGI_01903	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APCIGHGI_01904	1.15e-299	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APCIGHGI_01905	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APCIGHGI_01906	1.15e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
APCIGHGI_01907	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APCIGHGI_01908	2.92e-44	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
APCIGHGI_01909	4.92e-288	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
APCIGHGI_01910	3.57e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
APCIGHGI_01911	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APCIGHGI_01912	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
APCIGHGI_01913	4.68e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
APCIGHGI_01914	1.87e-250	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APCIGHGI_01915	2.83e-219	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APCIGHGI_01916	8.47e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
APCIGHGI_01919	1.83e-192	-	-	-	L	-	-	-	DNA replication protein
APCIGHGI_01920	7.49e-119	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
APCIGHGI_01926	5.57e-114	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01927	2.08e-104	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
APCIGHGI_01928	1.37e-290	-	-	-	L	-	-	-	MULE transposase domain
APCIGHGI_01929	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
APCIGHGI_01930	1.65e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01931	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
APCIGHGI_01932	2.03e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APCIGHGI_01933	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
APCIGHGI_01934	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
APCIGHGI_01935	9.91e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
APCIGHGI_01936	1.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
APCIGHGI_01937	2.51e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APCIGHGI_01938	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
APCIGHGI_01939	7.57e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
APCIGHGI_01940	1.76e-278	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
APCIGHGI_01941	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
APCIGHGI_01942	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
APCIGHGI_01943	5.95e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
APCIGHGI_01944	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APCIGHGI_01945	6.12e-98	-	-	-	-	-	-	-	-
APCIGHGI_01946	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
APCIGHGI_01947	2.53e-240	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
APCIGHGI_01948	2.39e-98	-	-	-	P	-	-	-	ArsC family
APCIGHGI_01949	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APCIGHGI_01950	1.91e-250	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APCIGHGI_01951	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APCIGHGI_01952	3.14e-157	-	-	-	S	-	-	-	repeat protein
APCIGHGI_01953	3.17e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
APCIGHGI_01954	1.08e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APCIGHGI_01955	0.0	-	-	-	S	-	-	-	amidohydrolase
APCIGHGI_01956	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APCIGHGI_01957	2.25e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
APCIGHGI_01958	3.96e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APCIGHGI_01959	2.68e-08	-	-	-	-	-	-	-	-
APCIGHGI_01960	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
APCIGHGI_01961	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APCIGHGI_01962	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APCIGHGI_01964	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
APCIGHGI_01965	1.24e-186	ylmH	-	-	S	-	-	-	S4 domain protein
APCIGHGI_01966	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
APCIGHGI_01967	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APCIGHGI_01968	9.01e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APCIGHGI_01969	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APCIGHGI_01970	5.43e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APCIGHGI_01971	3.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APCIGHGI_01972	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APCIGHGI_01973	4.46e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APCIGHGI_01974	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APCIGHGI_01975	3.49e-29	ftsL	-	-	D	-	-	-	Cell division protein FtsL
APCIGHGI_01976	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APCIGHGI_01977	8.95e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
APCIGHGI_01978	6.91e-76	-	-	-	-	-	-	-	-
APCIGHGI_01979	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
APCIGHGI_01980	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
APCIGHGI_01981	3.59e-26	-	-	-	-	-	-	-	-
APCIGHGI_01982	1.89e-65	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
APCIGHGI_01983	6.71e-06	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01984	8e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
APCIGHGI_01986	3.16e-82	-	-	-	S	-	-	-	Initiator Replication protein
APCIGHGI_01987	3.56e-219	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APCIGHGI_01989	1.56e-275	-	-	-	M	-	-	-	Glycosyl transferase family group 2
APCIGHGI_01992	1.11e-69	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_01993	4.46e-41	-	2.7.1.200	-	H	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APCIGHGI_01994	1.27e-249	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, galactitol-specific IIC component
APCIGHGI_01995	6.55e-39	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APCIGHGI_01996	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
APCIGHGI_01997	6.87e-05	-	-	-	M	ko:K07011	-	ko00000	extracellular polysaccharide biosynthetic process
APCIGHGI_01999	6.11e-37	-	-	-	L	-	-	-	integrase family
APCIGHGI_02000	1.95e-195	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
APCIGHGI_02001	7.53e-55	-	-	-	-	-	-	-	-
APCIGHGI_02002	1.16e-128	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
APCIGHGI_02003	7.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
APCIGHGI_02004	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
APCIGHGI_02005	1.82e-51	-	-	-	L	-	-	-	MULE transposase domain
APCIGHGI_02006	2.52e-203	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APCIGHGI_02007	2.06e-161	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain