ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MLKANEBP_00005 5.35e-289 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLKANEBP_00006 0.0 mdr - - EGP - - - Major Facilitator
MLKANEBP_00007 3.06e-21 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MLKANEBP_00008 1.29e-150 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLKANEBP_00009 7.6e-118 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLKANEBP_00010 7.75e-153 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MLKANEBP_00011 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MLKANEBP_00012 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLKANEBP_00014 3.3e-94 - - - K - - - transcriptional regulator
MLKANEBP_00015 1.39e-22 - - - K - - - transcriptional regulator
MLKANEBP_00016 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
MLKANEBP_00017 6.41e-105 - - - S - - - Cupin domain
MLKANEBP_00018 7.05e-89 - - - S - - - domain, Protein
MLKANEBP_00019 0.0 - - - S - - - domain, Protein
MLKANEBP_00020 4.95e-53 - - - S - - - Enterocin A Immunity
MLKANEBP_00021 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MLKANEBP_00022 3.16e-72 - - - - - - - -
MLKANEBP_00023 4.1e-251 flp - - V - - - Beta-lactamase
MLKANEBP_00024 1.19e-71 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MLKANEBP_00026 7.98e-310 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLKANEBP_00027 1.29e-196 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLKANEBP_00028 1.06e-164 - - - M - - - ErfK YbiS YcfS YnhG
MLKANEBP_00029 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MLKANEBP_00030 8.56e-217 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MLKANEBP_00031 2.45e-246 - - - C - - - FMN-dependent dehydrogenase
MLKANEBP_00032 2.79e-154 - - - - - - - -
MLKANEBP_00033 1.34e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLKANEBP_00034 3.09e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLKANEBP_00035 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLKANEBP_00036 6.93e-72 yheA - - S - - - Belongs to the UPF0342 family
MLKANEBP_00037 8.31e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MLKANEBP_00038 0.0 yhaN - - L - - - AAA domain
MLKANEBP_00039 3.19e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLKANEBP_00040 3.26e-199 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLKANEBP_00041 3.51e-74 - - - - - - - -
MLKANEBP_00042 1.38e-102 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MLKANEBP_00043 3.15e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00044 3.37e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLKANEBP_00045 9.15e-165 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLKANEBP_00046 5.52e-71 ytpP - - CO - - - Thioredoxin
MLKANEBP_00047 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLKANEBP_00048 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MLKANEBP_00049 0.0 - - - - - - - -
MLKANEBP_00050 2.69e-191 - - - K - - - Helix-turn-helix domain, rpiR family
MLKANEBP_00051 2.24e-41 - 2.7.1.208, 2.7.1.211 - G ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLKANEBP_00052 0.0 - - - G ko:K02755,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_00053 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_00054 1.09e-135 - - - S - - - Membrane
MLKANEBP_00055 2.45e-214 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
MLKANEBP_00056 6.25e-304 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MLKANEBP_00057 2.2e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLKANEBP_00058 4.56e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLKANEBP_00059 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
MLKANEBP_00060 1.69e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLKANEBP_00061 1.85e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
MLKANEBP_00062 5.91e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLKANEBP_00063 2.65e-80 yabA - - L - - - Involved in initiation control of chromosome replication
MLKANEBP_00064 1.66e-104 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLKANEBP_00065 2.09e-63 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLKANEBP_00066 1.29e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MLKANEBP_00067 6.76e-114 - - - S - - - ECF transporter, substrate-specific component
MLKANEBP_00068 8.02e-172 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MLKANEBP_00069 1.49e-138 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MLKANEBP_00070 5.62e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLKANEBP_00071 9.05e-170 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLKANEBP_00072 7.2e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLKANEBP_00073 4.46e-165 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MLKANEBP_00074 1.38e-298 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MLKANEBP_00075 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MLKANEBP_00076 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLKANEBP_00077 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MLKANEBP_00078 1.24e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLKANEBP_00079 6.41e-236 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLKANEBP_00080 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLKANEBP_00081 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_00082 4.92e-107 - - - - - - - -
MLKANEBP_00083 1.33e-100 - - - K - - - LytTr DNA-binding domain
MLKANEBP_00084 2.29e-175 - - - S - - - membrane
MLKANEBP_00085 2.22e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLKANEBP_00086 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLKANEBP_00087 2.17e-46 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLKANEBP_00088 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLKANEBP_00089 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLKANEBP_00090 2.35e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLKANEBP_00091 1.61e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLKANEBP_00092 2.41e-83 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLKANEBP_00093 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLKANEBP_00094 1.32e-255 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLKANEBP_00095 9.43e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MLKANEBP_00096 8.26e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLKANEBP_00097 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLKANEBP_00098 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
MLKANEBP_00099 3.27e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLKANEBP_00100 2.03e-67 yrzB - - S - - - Belongs to the UPF0473 family
MLKANEBP_00101 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLKANEBP_00102 1.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLKANEBP_00103 5.94e-70 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLKANEBP_00104 2.57e-91 yslB - - S - - - Protein of unknown function (DUF2507)
MLKANEBP_00105 1.33e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MLKANEBP_00106 1.42e-143 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLKANEBP_00107 3.18e-165 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MLKANEBP_00108 2.09e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLKANEBP_00109 1.37e-74 - - - - - - - -
MLKANEBP_00110 4.1e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLKANEBP_00111 4.5e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MLKANEBP_00112 9.27e-104 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLKANEBP_00113 1.62e-211 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLKANEBP_00114 2.5e-74 - - - - - - - -
MLKANEBP_00115 1.38e-199 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLKANEBP_00116 1.91e-135 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLKANEBP_00117 6.99e-134 yutD - - S - - - Protein of unknown function (DUF1027)
MLKANEBP_00118 1.9e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLKANEBP_00119 3.19e-139 - - - S - - - Protein of unknown function (DUF1461)
MLKANEBP_00120 1.45e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MLKANEBP_00121 4.65e-193 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MLKANEBP_00122 1.33e-75 - - - - - - - -
MLKANEBP_00123 1.02e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_00124 1.07e-163 - - - S - - - Alpha/beta hydrolase family
MLKANEBP_00125 2.63e-204 - - - M - - - Glycosyltransferase like family 2
MLKANEBP_00126 5.06e-182 - - - S - - - Protein of unknown function (DUF1002)
MLKANEBP_00127 1.58e-172 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLKANEBP_00128 1.45e-231 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLKANEBP_00129 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLKANEBP_00130 9.36e-111 - - - - - - - -
MLKANEBP_00131 2.57e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MLKANEBP_00132 2.69e-72 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
MLKANEBP_00133 9.33e-180 terC - - P - - - Integral membrane protein TerC family
MLKANEBP_00134 2.29e-85 yeaO - - S - - - Protein of unknown function, DUF488
MLKANEBP_00135 3.08e-159 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MLKANEBP_00136 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_00137 2.21e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00138 1.63e-233 yhaH - - S - - - Protein of unknown function (DUF805)
MLKANEBP_00139 2.73e-206 - - - L - - - HNH nucleases
MLKANEBP_00140 1.07e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MLKANEBP_00141 2.11e-271 - - - G - - - Glycosyl hydrolases family 8
MLKANEBP_00142 1.08e-288 ydaM - - M - - - Glycosyl transferase family group 2
MLKANEBP_00144 4.99e-47 - - - - - - - -
MLKANEBP_00145 6.75e-127 - - - - - - - -
MLKANEBP_00146 9.69e-25 - - - - - - - -
MLKANEBP_00147 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MLKANEBP_00148 7.83e-91 - - - S - - - Iron-sulphur cluster biosynthesis
MLKANEBP_00149 3.96e-05 ysdE - - P - - - Citrate transporter
MLKANEBP_00150 4.01e-218 ysdE - - P - - - Citrate transporter
MLKANEBP_00151 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
MLKANEBP_00152 9.9e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MLKANEBP_00153 2.11e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
MLKANEBP_00154 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00155 6.92e-130 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MLKANEBP_00156 8e-226 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLKANEBP_00157 1.09e-157 - - - - - - - -
MLKANEBP_00158 1.98e-26 - - - - - - - -
MLKANEBP_00159 0.0 - - - S - - - CAAX protease self-immunity
MLKANEBP_00161 4.72e-152 - - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_00162 2.48e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLKANEBP_00163 2.7e-257 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MLKANEBP_00164 9.1e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MLKANEBP_00165 3.54e-190 yycI - - S - - - YycH protein
MLKANEBP_00166 0.0 yycH - - S - - - YycH protein
MLKANEBP_00167 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLKANEBP_00168 9.77e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLKANEBP_00170 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_00171 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MLKANEBP_00172 8.36e-102 - - - - - - - -
MLKANEBP_00173 1.11e-191 - - - I - - - Acyl-transferase
MLKANEBP_00174 6.45e-204 arbx - - M - - - Glycosyl transferase family 8
MLKANEBP_00175 1.07e-238 - - - M - - - Glycosyl transferase family 8
MLKANEBP_00176 1.34e-235 - - - M - - - Glycosyl transferase family 8
MLKANEBP_00177 2.27e-214 arbZ - - I - - - Phosphate acyltransferases
MLKANEBP_00178 2.5e-51 - - - S - - - Cytochrome B5
MLKANEBP_00179 3.17e-149 - - - K - - - Transcriptional regulator, LysR family
MLKANEBP_00180 1.87e-292 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLKANEBP_00181 4.38e-74 - - - S - - - FMN_bind
MLKANEBP_00182 3.73e-65 - - - K - - - LysR substrate binding domain
MLKANEBP_00184 2.83e-62 - - - - - - - -
MLKANEBP_00185 1.3e-99 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MLKANEBP_00186 1.51e-234 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLKANEBP_00187 1.97e-159 - - - K - - - Bacterial regulatory proteins, tetR family
MLKANEBP_00188 2.93e-173 - - - - - - - -
MLKANEBP_00189 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLKANEBP_00190 7.42e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00191 1.96e-293 - - - S - - - Cysteine-rich secretory protein family
MLKANEBP_00192 7.25e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MLKANEBP_00193 1.49e-136 - - - - - - - -
MLKANEBP_00194 1.62e-256 yibE - - S - - - overlaps another CDS with the same product name
MLKANEBP_00195 1.71e-170 yibF - - S - - - overlaps another CDS with the same product name
MLKANEBP_00196 7.56e-205 - - - I - - - alpha/beta hydrolase fold
MLKANEBP_00197 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MLKANEBP_00198 8.53e-292 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLKANEBP_00199 2.9e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MLKANEBP_00200 1.74e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MLKANEBP_00201 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLKANEBP_00202 5.61e-113 usp5 - - T - - - universal stress protein
MLKANEBP_00203 7.56e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MLKANEBP_00204 4.46e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MLKANEBP_00205 2.84e-171 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_00206 6.38e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_00207 7.66e-141 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MLKANEBP_00208 3.65e-109 - - - - - - - -
MLKANEBP_00209 0.0 - - - S - - - Calcineurin-like phosphoesterase
MLKANEBP_00210 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLKANEBP_00211 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MLKANEBP_00212 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MLKANEBP_00213 1.29e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLKANEBP_00214 1.6e-127 yitW - - S - - - Iron-sulfur cluster assembly protein
MLKANEBP_00215 4.3e-297 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MLKANEBP_00216 1.88e-292 yttB - - EGP - - - Major Facilitator
MLKANEBP_00217 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MLKANEBP_00218 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MLKANEBP_00219 6.3e-91 - - - - - - - -
MLKANEBP_00220 2.15e-21 - - - - - - - -
MLKANEBP_00227 1.98e-96 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MLKANEBP_00228 0.0 - - - L - - - Helicase C-terminal domain protein
MLKANEBP_00229 3.83e-61 - - - L - - - Helicase C-terminal domain protein
MLKANEBP_00241 2.24e-284 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MLKANEBP_00242 1.5e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MLKANEBP_00243 5.18e-228 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLKANEBP_00244 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLKANEBP_00245 5.29e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLKANEBP_00246 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLKANEBP_00247 1.99e-99 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MLKANEBP_00248 0.0 - - - G - - - isomerase
MLKANEBP_00249 1.11e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLKANEBP_00250 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLKANEBP_00251 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLKANEBP_00252 2.7e-10 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLKANEBP_00253 8.27e-190 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLKANEBP_00254 1.05e-225 - - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
MLKANEBP_00255 0.0 - - - G - - - Protein of unknown function (DUF4038)
MLKANEBP_00256 5.47e-199 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLKANEBP_00257 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_00258 4.63e-225 - - - I - - - alpha/beta hydrolase fold
MLKANEBP_00259 9.97e-103 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MLKANEBP_00260 3.89e-77 - - - G - - - polysaccharide catabolic process
MLKANEBP_00261 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
MLKANEBP_00262 2.88e-223 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLKANEBP_00263 1.05e-274 - - - EGP - - - Transporter, major facilitator family protein
MLKANEBP_00264 0.0 - - - S - - - Domain of unknown function (DUF5060)
MLKANEBP_00265 1.79e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLKANEBP_00266 8.15e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MLKANEBP_00267 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MLKANEBP_00268 1.46e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLKANEBP_00269 2.47e-221 - - - - - - - -
MLKANEBP_00270 0.0 icaA - - M - - - Glycosyl transferase family group 2
MLKANEBP_00271 4.97e-81 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MLKANEBP_00284 4.05e-112 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLKANEBP_00285 4.67e-116 gtcA1 - - S - - - Teichoic acid glycosylation protein
MLKANEBP_00286 8.53e-104 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MLKANEBP_00287 7.02e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MLKANEBP_00288 1.14e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MLKANEBP_00289 6.78e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLKANEBP_00290 3.81e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLKANEBP_00291 1.39e-277 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MLKANEBP_00292 3.82e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MLKANEBP_00293 2.95e-61 - - - - - - - -
MLKANEBP_00294 2.13e-227 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLKANEBP_00295 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLKANEBP_00296 4.13e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MLKANEBP_00297 7.42e-112 - - - - - - - -
MLKANEBP_00298 1.02e-93 - - - - - - - -
MLKANEBP_00299 1.25e-62 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MLKANEBP_00300 1.48e-127 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MLKANEBP_00301 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MLKANEBP_00302 3.43e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MLKANEBP_00303 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MLKANEBP_00304 9.05e-55 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MLKANEBP_00305 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLKANEBP_00306 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLKANEBP_00307 2.91e-175 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MLKANEBP_00308 2.56e-209 coiA - - S ko:K06198 - ko00000 Competence protein
MLKANEBP_00309 7.54e-149 yjbH - - Q - - - Thioredoxin
MLKANEBP_00310 1.46e-145 - - - S - - - CYTH
MLKANEBP_00311 1.15e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MLKANEBP_00312 5.49e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLKANEBP_00313 1.81e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLKANEBP_00314 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MLKANEBP_00315 8.93e-153 - - - S - - - SNARE associated Golgi protein
MLKANEBP_00316 1.06e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MLKANEBP_00317 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MLKANEBP_00318 8.1e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MLKANEBP_00319 8.9e-270 XK27_05220 - - S - - - AI-2E family transporter
MLKANEBP_00320 1.75e-134 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLKANEBP_00321 1.28e-89 - - - S - - - Protein of unknown function (DUF1149)
MLKANEBP_00322 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLKANEBP_00323 4.09e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
MLKANEBP_00324 2.26e-306 ymfH - - S - - - Peptidase M16
MLKANEBP_00325 8.02e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MLKANEBP_00326 1.43e-160 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MLKANEBP_00327 1.73e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLKANEBP_00328 6.24e-247 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLKANEBP_00329 2.13e-292 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MLKANEBP_00330 3.37e-271 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MLKANEBP_00331 2.05e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MLKANEBP_00332 8.33e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MLKANEBP_00333 2.26e-137 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MLKANEBP_00334 1.75e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLKANEBP_00335 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLKANEBP_00336 6.43e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLKANEBP_00337 1.88e-21 - - - - - - - -
MLKANEBP_00338 6.85e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLKANEBP_00339 4.36e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLKANEBP_00340 1.71e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MLKANEBP_00341 9.38e-228 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLKANEBP_00342 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLKANEBP_00343 4.02e-284 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLKANEBP_00344 5.82e-272 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MLKANEBP_00345 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLKANEBP_00346 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLKANEBP_00347 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MLKANEBP_00348 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MLKANEBP_00349 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLKANEBP_00350 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLKANEBP_00351 3.8e-118 - - - S - - - Short repeat of unknown function (DUF308)
MLKANEBP_00352 2.44e-116 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLKANEBP_00353 5.03e-81 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLKANEBP_00354 2.69e-51 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLKANEBP_00355 1.86e-164 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLKANEBP_00356 1.17e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MLKANEBP_00357 2.16e-129 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLKANEBP_00358 0.0 - - - S - - - SH3-like domain
MLKANEBP_00359 0.0 ycaM - - E - - - amino acid
MLKANEBP_00361 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MLKANEBP_00362 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLKANEBP_00363 9.96e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MLKANEBP_00364 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLKANEBP_00365 1.07e-125 - - - - - - - -
MLKANEBP_00366 1.02e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLKANEBP_00367 1.15e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLKANEBP_00368 3.95e-174 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MLKANEBP_00369 5.09e-26 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MLKANEBP_00370 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MLKANEBP_00371 5.26e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLKANEBP_00372 7.27e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MLKANEBP_00373 2.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MLKANEBP_00374 1.04e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_00375 2.65e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_00376 9.5e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_00377 1.06e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLKANEBP_00378 3.38e-221 ybbR - - S - - - YbbR-like protein
MLKANEBP_00379 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLKANEBP_00380 4.85e-191 - - - S - - - hydrolase
MLKANEBP_00381 1.45e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLKANEBP_00382 7.3e-156 - - - - - - - -
MLKANEBP_00383 2.73e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLKANEBP_00384 1.37e-269 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MLKANEBP_00385 4.66e-196 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLKANEBP_00386 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_00387 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_00388 6.14e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLKANEBP_00389 0.0 - - - E - - - Amino acid permease
MLKANEBP_00391 1.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLKANEBP_00392 2.34e-119 - - - S - - - VanZ like family
MLKANEBP_00393 1.97e-171 yebC - - K - - - Transcriptional regulatory protein
MLKANEBP_00394 7.38e-29 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MLKANEBP_00395 9.02e-183 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MLKANEBP_00396 5.57e-224 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MLKANEBP_00397 1.55e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MLKANEBP_00398 9e-94 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MLKANEBP_00399 1.33e-25 - - - - - - - -
MLKANEBP_00400 2.61e-120 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MLKANEBP_00401 4.19e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MLKANEBP_00402 1.35e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLKANEBP_00404 1.05e-170 - - - M - - - Protein of unknown function (DUF3737)
MLKANEBP_00405 3.52e-224 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MLKANEBP_00406 4.53e-41 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MLKANEBP_00407 1.86e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLKANEBP_00408 1.68e-81 - - - S - - - SdpI/YhfL protein family
MLKANEBP_00409 1.84e-123 - - - K - - - Transcriptional regulatory protein, C terminal
MLKANEBP_00410 0.0 yclK - - T - - - Histidine kinase
MLKANEBP_00411 4.37e-81 XK27_00915 - - C - - - Luciferase-like monooxygenase
MLKANEBP_00412 1.53e-159 XK27_00915 - - C - - - Luciferase-like monooxygenase
MLKANEBP_00413 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLKANEBP_00414 1.93e-139 vanZ - - V - - - VanZ like family
MLKANEBP_00415 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MLKANEBP_00416 5.4e-316 - - - EGP - - - Major Facilitator
MLKANEBP_00417 7.36e-251 ampC - - V - - - Beta-lactamase
MLKANEBP_00420 2.17e-85 - - - - - - - -
MLKANEBP_00421 0.0 - - - S ko:K06919 - ko00000 DNA primase
MLKANEBP_00422 1.18e-47 - - - - - - - -
MLKANEBP_00423 6.8e-46 - - - - - - - -
MLKANEBP_00424 3.84e-90 - - - - - - - -
MLKANEBP_00425 2.58e-49 - - - - - - - -
MLKANEBP_00427 3.5e-75 - - - K - - - Transcriptional
MLKANEBP_00428 1.58e-266 - - - L - - - Belongs to the 'phage' integrase family
MLKANEBP_00429 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MLKANEBP_00430 4.64e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MLKANEBP_00431 1.01e-235 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLKANEBP_00432 2.52e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLKANEBP_00433 4.93e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLKANEBP_00434 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLKANEBP_00435 4.13e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MLKANEBP_00436 4.36e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLKANEBP_00437 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLKANEBP_00438 6.82e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLKANEBP_00439 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLKANEBP_00440 1.22e-220 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLKANEBP_00441 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLKANEBP_00442 7.03e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MLKANEBP_00443 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
MLKANEBP_00444 2.04e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MLKANEBP_00445 7.58e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MLKANEBP_00446 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
MLKANEBP_00447 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MLKANEBP_00448 6.39e-102 uspA - - T - - - universal stress protein
MLKANEBP_00449 1.41e-49 - - - - - - - -
MLKANEBP_00450 1.18e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MLKANEBP_00451 9.44e-109 - - - S - - - Protein of unknown function (DUF1694)
MLKANEBP_00452 1.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLKANEBP_00453 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLKANEBP_00454 1.29e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLKANEBP_00455 4.62e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLKANEBP_00456 1.56e-165 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLKANEBP_00457 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLKANEBP_00458 3.52e-261 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLKANEBP_00459 1.83e-163 - - - S - - - Haloacid dehalogenase-like hydrolase
MLKANEBP_00460 2.34e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
MLKANEBP_00461 2.03e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MLKANEBP_00462 1.82e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MLKANEBP_00463 6.61e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
MLKANEBP_00464 1.45e-14 - - - S - - - Protein of unknown function (DUF4044)
MLKANEBP_00465 4.84e-71 - - - S - - - Protein of unknown function (DUF3397)
MLKANEBP_00466 3.95e-93 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MLKANEBP_00467 5.41e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLKANEBP_00468 1.32e-71 ftsL - - D - - - Cell division protein FtsL
MLKANEBP_00469 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLKANEBP_00470 8e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLKANEBP_00471 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLKANEBP_00472 4.93e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLKANEBP_00473 1.71e-182 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLKANEBP_00474 1.02e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLKANEBP_00475 5.9e-313 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLKANEBP_00476 4.09e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLKANEBP_00477 1.36e-39 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
MLKANEBP_00478 4.87e-193 ylmH - - S - - - S4 domain protein
MLKANEBP_00479 1.18e-141 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MLKANEBP_00480 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLKANEBP_00481 8.09e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MLKANEBP_00482 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MLKANEBP_00483 1.02e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLKANEBP_00484 1.47e-76 XK27_04120 - - S - - - Putative amino acid metabolism
MLKANEBP_00485 1.62e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLKANEBP_00486 1.58e-161 pgm - - G - - - Phosphoglycerate mutase family
MLKANEBP_00487 1.88e-134 - - - S - - - repeat protein
MLKANEBP_00488 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLKANEBP_00489 0.0 - - - L - - - Nuclease-related domain
MLKANEBP_00490 1.29e-233 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MLKANEBP_00491 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLKANEBP_00492 3.13e-46 ykzG - - S - - - Belongs to the UPF0356 family
MLKANEBP_00493 2.52e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLKANEBP_00494 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MLKANEBP_00495 2.75e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLKANEBP_00496 4.73e-69 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MLKANEBP_00497 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MLKANEBP_00498 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLKANEBP_00499 1.37e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MLKANEBP_00500 2.19e-131 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MLKANEBP_00501 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MLKANEBP_00502 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MLKANEBP_00503 3.78e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MLKANEBP_00504 4.08e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLKANEBP_00505 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLKANEBP_00506 1.45e-195 - - - - - - - -
MLKANEBP_00507 8.19e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLKANEBP_00508 3.02e-294 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLKANEBP_00509 8.42e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLKANEBP_00510 1.17e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MLKANEBP_00511 7.3e-245 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLKANEBP_00512 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLKANEBP_00513 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLKANEBP_00514 1.39e-106 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLKANEBP_00515 5.48e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLKANEBP_00516 1.14e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLKANEBP_00517 1.23e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLKANEBP_00518 2.42e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLKANEBP_00519 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLKANEBP_00520 8.12e-262 pbpX1 - - V - - - Beta-lactamase
MLKANEBP_00521 5.27e-57 - - - I - - - Protein of unknown function (DUF2974)
MLKANEBP_00522 2.95e-307 - - - I - - - Protein of unknown function (DUF2974)
MLKANEBP_00523 1.18e-55 - - - C - - - FMN_bind
MLKANEBP_00524 1.01e-104 - - - - - - - -
MLKANEBP_00525 0.0 - - - - - - - -
MLKANEBP_00526 4.65e-228 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MLKANEBP_00527 5.52e-24 adhC 1.1.1.90 - C ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 S-(hydroxymethyl)glutathione dehydrogenase activity
MLKANEBP_00528 8.04e-188 - - - - - - - -
MLKANEBP_00532 1.93e-25 alkD - - L - - - DNA alkylation repair enzyme
MLKANEBP_00533 7.14e-91 alkD - - L - - - DNA alkylation repair enzyme
MLKANEBP_00534 3.08e-52 - - - S - - - Transglycosylase associated protein
MLKANEBP_00535 6.28e-10 - - - S - - - CsbD-like
MLKANEBP_00536 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_00537 1.62e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
MLKANEBP_00538 4.98e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MLKANEBP_00539 4.75e-80 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MLKANEBP_00540 4.68e-104 - - - - - - - -
MLKANEBP_00541 1.68e-179 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_00542 2.84e-94 - - - S - - - Domain of unknown function (DUF3284)
MLKANEBP_00543 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_00544 3.63e-56 - - - K ko:K03492 - ko00000,ko03000 UTRA
MLKANEBP_00545 1.91e-55 - - - - - - - -
MLKANEBP_00546 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_00547 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_00548 3.69e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MLKANEBP_00549 1.01e-111 yfhC - - C - - - Nitroreductase family
MLKANEBP_00550 4.93e-141 - - - S - - - Domain of unknown function (DUF4767)
MLKANEBP_00551 2.12e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLKANEBP_00552 1.19e-194 - - - S - - - Uncharacterised protein, DegV family COG1307
MLKANEBP_00553 2.64e-128 - - - I - - - PAP2 superfamily
MLKANEBP_00554 5.99e-244 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MLKANEBP_00556 2.59e-229 int3 - - L - - - Belongs to the 'phage' integrase family
MLKANEBP_00557 1.09e-34 - - - - - - - -
MLKANEBP_00558 4.66e-128 - - - - - - - -
MLKANEBP_00559 0.000281 - - - - - - - -
MLKANEBP_00560 9.27e-75 - - - K - - - Cro/C1-type HTH DNA-binding domain
MLKANEBP_00561 2.16e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_00562 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MLKANEBP_00563 6.63e-222 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLKANEBP_00564 1.53e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLKANEBP_00565 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MLKANEBP_00566 1.03e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLKANEBP_00567 1.74e-199 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLKANEBP_00568 4.45e-127 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_00569 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLKANEBP_00570 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLKANEBP_00571 0.0 - - - M - - - domain protein
MLKANEBP_00572 5.14e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLKANEBP_00573 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MLKANEBP_00574 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLKANEBP_00575 7.54e-200 - - - I - - - Alpha/beta hydrolase family
MLKANEBP_00576 7.35e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MLKANEBP_00577 2.76e-60 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MLKANEBP_00578 6.24e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MLKANEBP_00579 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MLKANEBP_00580 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
MLKANEBP_00581 6.03e-19 - - - - - - - -
MLKANEBP_00582 7.06e-166 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MLKANEBP_00583 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00584 4.42e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MLKANEBP_00585 2.09e-83 - - - S - - - Domain of unknown function DUF1828
MLKANEBP_00586 5.21e-71 - - - - - - - -
MLKANEBP_00587 1.56e-228 citR - - K - - - Putative sugar-binding domain
MLKANEBP_00588 3.82e-312 - - - S - - - Putative threonine/serine exporter
MLKANEBP_00589 1.88e-111 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLKANEBP_00590 1.54e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MLKANEBP_00591 1.17e-65 - - - - - - - -
MLKANEBP_00592 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLKANEBP_00593 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLKANEBP_00594 1.74e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MLKANEBP_00595 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MLKANEBP_00596 9.94e-287 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLKANEBP_00597 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLKANEBP_00598 2.72e-197 - - - S - - - reductase
MLKANEBP_00599 3.29e-193 yxeH - - S - - - hydrolase
MLKANEBP_00600 2.31e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLKANEBP_00601 5.04e-298 yhdG - - E ko:K03294 - ko00000 Amino Acid
MLKANEBP_00602 4.52e-140 yngC - - S - - - SNARE associated Golgi protein
MLKANEBP_00603 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLKANEBP_00604 3.01e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLKANEBP_00605 9.21e-273 oatA - - I - - - Acyltransferase
MLKANEBP_00606 6.51e-113 oatA - - I - - - Acyltransferase
MLKANEBP_00607 6.35e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLKANEBP_00608 1.5e-186 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLKANEBP_00609 2.25e-45 - - - S - - - Lipopolysaccharide assembly protein A domain
MLKANEBP_00610 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MLKANEBP_00611 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLKANEBP_00612 3.9e-33 - - - S - - - Protein of unknown function (DUF2929)
MLKANEBP_00613 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MLKANEBP_00614 7.76e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLKANEBP_00615 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MLKANEBP_00616 1e-216 yitL - - S ko:K00243 - ko00000 S1 domain
MLKANEBP_00617 2.19e-218 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MLKANEBP_00618 6.56e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLKANEBP_00619 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLKANEBP_00620 5.75e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLKANEBP_00621 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLKANEBP_00622 2.1e-18 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLKANEBP_00623 1.25e-105 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLKANEBP_00624 7.33e-71 - - - M - - - Lysin motif
MLKANEBP_00625 1.28e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MLKANEBP_00626 4.07e-270 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MLKANEBP_00627 3.15e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MLKANEBP_00628 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLKANEBP_00629 2.22e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MLKANEBP_00630 1.3e-207 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLKANEBP_00631 8.15e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLKANEBP_00632 4.94e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MLKANEBP_00633 1.31e-96 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MLKANEBP_00634 1.34e-77 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MLKANEBP_00635 1.64e-47 yozE - - S - - - Belongs to the UPF0346 family
MLKANEBP_00636 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLKANEBP_00637 8.81e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLKANEBP_00638 8.96e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLKANEBP_00639 1.07e-201 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MLKANEBP_00640 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLKANEBP_00641 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLKANEBP_00642 2.27e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MLKANEBP_00643 3.29e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLKANEBP_00644 4.61e-308 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLKANEBP_00645 3.4e-230 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MLKANEBP_00646 1.72e-85 - - - - - - - -
MLKANEBP_00647 4.82e-296 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_00648 1.25e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLKANEBP_00649 2.82e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
MLKANEBP_00650 7.42e-89 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLKANEBP_00651 9.18e-83 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLKANEBP_00652 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MLKANEBP_00653 0.0 - - - E - - - Amino acid permease
MLKANEBP_00654 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MLKANEBP_00655 1.13e-312 ynbB - - P - - - aluminum resistance
MLKANEBP_00656 6.35e-154 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MLKANEBP_00657 7.3e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MLKANEBP_00658 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MLKANEBP_00659 1.47e-105 - - - C - - - Flavodoxin
MLKANEBP_00660 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MLKANEBP_00661 4.33e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MLKANEBP_00662 8.43e-148 - - - I - - - Acid phosphatase homologues
MLKANEBP_00663 5.22e-89 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLKANEBP_00664 1.71e-265 - - - V - - - Beta-lactamase
MLKANEBP_00665 2.42e-201 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MLKANEBP_00666 2.46e-121 - - - S - - - ECF-type riboflavin transporter, S component
MLKANEBP_00667 1.84e-281 - - - S - - - Putative peptidoglycan binding domain
MLKANEBP_00668 1.37e-93 - - - - - - - -
MLKANEBP_00669 9.84e-146 - - - - - - - -
MLKANEBP_00670 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_00671 2.78e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MLKANEBP_00672 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLKANEBP_00673 5.68e-165 - - - M - - - Glycosyl transferases group 1
MLKANEBP_00674 5.84e-129 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLKANEBP_00675 7.57e-211 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLKANEBP_00676 2.61e-19 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLKANEBP_00677 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLKANEBP_00678 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLKANEBP_00679 9.5e-39 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MLKANEBP_00680 1.72e-208 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
MLKANEBP_00681 5.93e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
MLKANEBP_00682 5.96e-205 - - - K - - - Transcriptional regulator
MLKANEBP_00683 2.55e-214 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MLKANEBP_00684 1.08e-212 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MLKANEBP_00685 1.31e-211 yvgN - - C - - - Aldo keto reductase
MLKANEBP_00686 5.42e-275 - - - S - - - SLAP domain
MLKANEBP_00687 1.7e-133 - - - K - - - Acetyltransferase (GNAT) domain
MLKANEBP_00690 2.77e-134 - - - - - - - -
MLKANEBP_00691 1.09e-79 - - - K - - - Transcriptional regulator
MLKANEBP_00692 8.07e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLKANEBP_00693 3.34e-211 - - - S - - - reductase
MLKANEBP_00694 1.13e-219 - - - - - - - -
MLKANEBP_00695 4.2e-42 lysR - - K - - - Transcriptional regulator
MLKANEBP_00696 3.25e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MLKANEBP_00697 2.48e-131 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MLKANEBP_00698 6.13e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_00699 3.59e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_00700 2.66e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLKANEBP_00701 1.72e-142 - - - G - - - Phosphoglycerate mutase family
MLKANEBP_00702 1.81e-223 - - - S ko:K07045 - ko00000 Amidohydrolase
MLKANEBP_00703 5.1e-43 - - - - - - - -
MLKANEBP_00704 1.41e-141 - - - - - - - -
MLKANEBP_00705 3.18e-140 - - - - - - - -
MLKANEBP_00706 3.18e-167 - - - F - - - glutamine amidotransferase
MLKANEBP_00707 9.73e-275 - - - EGP - - - Major Facilitator Superfamily
MLKANEBP_00708 1.7e-199 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MLKANEBP_00709 2.53e-152 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MLKANEBP_00710 2.43e-100 - - - - - - - -
MLKANEBP_00711 1.24e-113 - - - FG - - - HIT domain
MLKANEBP_00712 5.21e-82 - - - - - - - -
MLKANEBP_00713 4.91e-121 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLKANEBP_00714 1.62e-135 - - - S - - - Alpha/beta hydrolase family
MLKANEBP_00715 6.2e-131 - - - - - - - -
MLKANEBP_00716 1.22e-103 - - - - - - - -
MLKANEBP_00717 2.72e-188 - - - F - - - Phosphorylase superfamily
MLKANEBP_00718 3.34e-139 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MLKANEBP_00719 2.07e-189 - - - F - - - Phosphorylase superfamily
MLKANEBP_00720 5.98e-108 - - - F - - - Phosphorylase superfamily
MLKANEBP_00721 2.55e-64 - - - F - - - Phosphorylase superfamily
MLKANEBP_00722 1.79e-144 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MLKANEBP_00723 1.24e-47 - - - - - - - -
MLKANEBP_00724 2.58e-67 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MLKANEBP_00725 9.6e-137 - - - - - - - -
MLKANEBP_00726 8.78e-52 - - - - - - - -
MLKANEBP_00727 3.77e-216 mleR - - K - - - LysR family
MLKANEBP_00728 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MLKANEBP_00729 3.74e-130 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MLKANEBP_00730 2.2e-310 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MLKANEBP_00731 2.27e-248 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MLKANEBP_00732 5.33e-147 - - - S - - - L,D-transpeptidase catalytic domain
MLKANEBP_00733 1.23e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MLKANEBP_00734 3.03e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLKANEBP_00735 2.55e-118 - - - L - - - nuclease
MLKANEBP_00736 2.51e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MLKANEBP_00737 2.81e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MLKANEBP_00738 4.76e-306 steT - - E ko:K03294 - ko00000 amino acid
MLKANEBP_00739 4.4e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLKANEBP_00740 6.01e-54 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLKANEBP_00741 3.16e-190 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLKANEBP_00742 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate carboxylase activity
MLKANEBP_00743 0.0 - - - - - - - -
MLKANEBP_00744 0.0 - - - - - - - -
MLKANEBP_00745 0.0 - - - - - - - -
MLKANEBP_00746 2.29e-224 yobV3 - - K - - - WYL domain
MLKANEBP_00747 4.35e-108 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MLKANEBP_00748 1.57e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MLKANEBP_00749 3.78e-72 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MLKANEBP_00750 1.16e-148 - - - C - - - Aldo/keto reductase family
MLKANEBP_00751 7.12e-80 - - - C - - - aldo keto reductase
MLKANEBP_00752 1.54e-187 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
MLKANEBP_00753 1.51e-24 - - - C - - - Flavodoxin
MLKANEBP_00755 9.87e-139 - - - C - - - Flavodoxin
MLKANEBP_00756 2.88e-130 - - - P - - - esterase
MLKANEBP_00757 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MLKANEBP_00758 3.77e-32 - - - - - - - -
MLKANEBP_00759 1.29e-182 - - - C - - - Flavodoxin
MLKANEBP_00760 7.38e-127 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MLKANEBP_00761 3.1e-30 - - - C - - - Flavodoxin
MLKANEBP_00762 1.39e-190 - - - P - - - FAD-binding domain
MLKANEBP_00763 2.54e-101 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLKANEBP_00765 0.0 yagE - - E - - - amino acid
MLKANEBP_00766 1.37e-15 - - - S - - - Alpha beta hydrolase
MLKANEBP_00767 6e-59 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLKANEBP_00768 4.13e-18 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLKANEBP_00769 1.43e-24 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MLKANEBP_00770 8.53e-215 - - - S - - - Conserved hypothetical protein 698
MLKANEBP_00771 1.17e-130 - - - - - - - -
MLKANEBP_00772 1.9e-140 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLKANEBP_00773 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLKANEBP_00774 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLKANEBP_00775 9.2e-39 - - - K - - - Transcriptional regulator
MLKANEBP_00776 1.96e-184 - - - K - - - Transcriptional regulator
MLKANEBP_00777 3.65e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MLKANEBP_00778 7.02e-146 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLKANEBP_00779 9.73e-55 - - - K - - - Helix-turn-helix domain
MLKANEBP_00780 4.78e-165 - - - S - - - Protein of unknown function (DUF1275)
MLKANEBP_00781 3.46e-87 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MLKANEBP_00783 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_00784 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_00785 1.74e-272 - - - EGP - - - Transmembrane secretion effector
MLKANEBP_00786 1.06e-110 rmaD - - K - - - transcriptional
MLKANEBP_00787 3.92e-76 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLKANEBP_00788 3.43e-07 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLKANEBP_00789 1.1e-255 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLKANEBP_00790 2.62e-138 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
MLKANEBP_00791 1.27e-119 flaR - - F - - - topology modulation protein
MLKANEBP_00792 1.03e-100 - - - - - - - -
MLKANEBP_00793 5.95e-250 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MLKANEBP_00794 7.16e-71 - - - S - - - EDD domain protein, DegV family
MLKANEBP_00795 7.03e-104 - - - S - - - EDD domain protein, DegV family
MLKANEBP_00796 2.95e-87 - - - - - - - -
MLKANEBP_00797 0.0 FbpA - - K - - - Fibronectin-binding protein
MLKANEBP_00798 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLKANEBP_00799 2.05e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLKANEBP_00800 2.88e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLKANEBP_00801 6.23e-113 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLKANEBP_00802 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MLKANEBP_00803 2.01e-310 cpdA - - S - - - Calcineurin-like phosphoesterase
MLKANEBP_00804 2.39e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MLKANEBP_00805 2.83e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLKANEBP_00806 1.61e-136 ypsA - - S - - - Belongs to the UPF0398 family
MLKANEBP_00807 1.99e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLKANEBP_00808 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MLKANEBP_00809 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLKANEBP_00810 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MLKANEBP_00811 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MLKANEBP_00812 8.23e-117 ypmB - - S - - - Protein conserved in bacteria
MLKANEBP_00813 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MLKANEBP_00814 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MLKANEBP_00815 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MLKANEBP_00816 6.78e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MLKANEBP_00817 3.39e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MLKANEBP_00818 1.64e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MLKANEBP_00819 2.09e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLKANEBP_00820 1.01e-187 - - - K - - - SIS domain
MLKANEBP_00821 1.18e-140 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLKANEBP_00822 2.04e-73 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLKANEBP_00823 1.14e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLKANEBP_00824 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MLKANEBP_00825 1.05e-228 - - - - - - - -
MLKANEBP_00826 1.57e-181 - - - - - - - -
MLKANEBP_00827 1.72e-123 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLKANEBP_00828 1.04e-37 - - - - - - - -
MLKANEBP_00829 3.64e-175 - - - - - - - -
MLKANEBP_00830 2.03e-186 - - - - - - - -
MLKANEBP_00831 1.51e-174 - - - - - - - -
MLKANEBP_00832 1.09e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLKANEBP_00833 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MLKANEBP_00834 7.64e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLKANEBP_00835 3.45e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLKANEBP_00836 4.48e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MLKANEBP_00837 1.87e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MLKANEBP_00838 2.24e-162 - - - S - - - Peptidase family M23
MLKANEBP_00839 3.01e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLKANEBP_00840 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLKANEBP_00841 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MLKANEBP_00842 1.05e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MLKANEBP_00843 5.41e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MLKANEBP_00844 6.28e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLKANEBP_00845 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLKANEBP_00846 1.82e-226 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MLKANEBP_00847 4.38e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MLKANEBP_00848 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MLKANEBP_00849 2.71e-196 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLKANEBP_00850 3.22e-133 - - - S - - - Peptidase family M23
MLKANEBP_00851 6.31e-144 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLKANEBP_00852 2.17e-209 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLKANEBP_00853 1.4e-157 - - - - - - - -
MLKANEBP_00854 4.04e-207 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLKANEBP_00855 1.58e-282 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MLKANEBP_00856 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MLKANEBP_00857 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLKANEBP_00858 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLKANEBP_00859 3.65e-28 - - - S - - - Bacterial protein of unknown function (DUF898)
MLKANEBP_00860 1.92e-141 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MLKANEBP_00861 0.0 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
MLKANEBP_00862 2.86e-05 - - - M - - - Leucine-rich repeat (LRR) protein
MLKANEBP_00863 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MLKANEBP_00864 5.4e-282 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLKANEBP_00865 0.0 - - - - - - - -
MLKANEBP_00866 3.69e-157 - - - G - - - Antibiotic biosynthesis monooxygenase
MLKANEBP_00867 8.29e-129 - - - - - - - -
MLKANEBP_00868 1.82e-139 - - - K - - - LysR substrate binding domain
MLKANEBP_00869 8.62e-22 - - - - - - - -
MLKANEBP_00870 3.35e-291 - - - S - - - Sterol carrier protein domain
MLKANEBP_00871 3.83e-127 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MLKANEBP_00872 4.54e-95 lysR5 - - K - - - LysR substrate binding domain
MLKANEBP_00873 1.32e-90 lysR5 - - K - - - LysR substrate binding domain
MLKANEBP_00874 2.3e-100 - - - P - - - Cation transporter/ATPase, N-terminus
MLKANEBP_00875 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MLKANEBP_00876 1.19e-113 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
MLKANEBP_00877 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLKANEBP_00878 4.53e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MLKANEBP_00879 1.73e-219 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLKANEBP_00880 1.72e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MLKANEBP_00881 6.15e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MLKANEBP_00883 7.02e-103 - - - K - - - Acetyltransferase (GNAT) domain
MLKANEBP_00884 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLKANEBP_00885 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MLKANEBP_00886 6.07e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MLKANEBP_00887 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLKANEBP_00888 5.85e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLKANEBP_00889 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MLKANEBP_00890 7.55e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLKANEBP_00891 2.1e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLKANEBP_00892 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MLKANEBP_00893 2.49e-228 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLKANEBP_00894 8.54e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLKANEBP_00895 9.65e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLKANEBP_00896 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLKANEBP_00897 3.95e-65 ylxQ - - J - - - ribosomal protein
MLKANEBP_00898 6.47e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MLKANEBP_00899 3.76e-268 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MLKANEBP_00900 2.39e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MLKANEBP_00901 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLKANEBP_00902 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLKANEBP_00903 1.35e-255 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MLKANEBP_00904 1.89e-188 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MLKANEBP_00905 2.23e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLKANEBP_00906 2.53e-114 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLKANEBP_00907 7.13e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MLKANEBP_00908 1.45e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLKANEBP_00909 2.05e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MLKANEBP_00910 6.34e-255 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MLKANEBP_00911 1.59e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MLKANEBP_00912 2.67e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MLKANEBP_00913 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MLKANEBP_00914 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_00915 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_00916 3.18e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MLKANEBP_00917 2.97e-50 ynzC - - S - - - UPF0291 protein
MLKANEBP_00918 2.83e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLKANEBP_00919 1.4e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MLKANEBP_00920 1.19e-156 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MLKANEBP_00921 2.58e-226 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MLKANEBP_00922 0.0 - - - S - - - Bacterial membrane protein, YfhO
MLKANEBP_00923 2.48e-91 - - - S - - - GtrA-like protein
MLKANEBP_00924 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLKANEBP_00925 5.01e-164 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MLKANEBP_00926 1.07e-124 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLKANEBP_00927 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MLKANEBP_00928 1.9e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLKANEBP_00929 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLKANEBP_00930 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MLKANEBP_00931 1.16e-88 - - - - - - - -
MLKANEBP_00932 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLKANEBP_00933 1.12e-228 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLKANEBP_00934 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MLKANEBP_00935 4.48e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLKANEBP_00936 1.32e-123 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MLKANEBP_00937 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLKANEBP_00938 1.31e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLKANEBP_00939 4.9e-33 - - - - - - - -
MLKANEBP_00940 1.25e-147 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MLKANEBP_00941 3.83e-167 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MLKANEBP_00942 9.31e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLKANEBP_00943 2.15e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLKANEBP_00944 1.86e-38 - - - - - - - -
MLKANEBP_00945 3.62e-268 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MLKANEBP_00946 1.74e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MLKANEBP_00947 1.33e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLKANEBP_00948 4.47e-186 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLKANEBP_00949 4.47e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MLKANEBP_00950 1.8e-223 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MLKANEBP_00951 2.83e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLKANEBP_00952 1.5e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLKANEBP_00953 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLKANEBP_00954 3.66e-132 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLKANEBP_00955 1.72e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLKANEBP_00956 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLKANEBP_00957 1.22e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
MLKANEBP_00958 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLKANEBP_00959 6.48e-148 - - - - - - - -
MLKANEBP_00960 2.41e-45 - - - - - - - -
MLKANEBP_00961 2.91e-121 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MLKANEBP_00962 8.7e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLKANEBP_00963 6.01e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLKANEBP_00964 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLKANEBP_00965 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLKANEBP_00966 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLKANEBP_00967 1.82e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MLKANEBP_00968 9.95e-70 - - - - - - - -
MLKANEBP_00969 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MLKANEBP_00970 9.84e-236 - - - S - - - AAA domain
MLKANEBP_00971 1.27e-104 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLKANEBP_00972 1.14e-27 - - - - - - - -
MLKANEBP_00973 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MLKANEBP_00974 6.91e-164 - - - G - - - Belongs to the phosphoglycerate mutase family
MLKANEBP_00975 8.09e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
MLKANEBP_00976 4.67e-154 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLKANEBP_00977 3.63e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MLKANEBP_00978 5.27e-16 - - - - - - - -
MLKANEBP_00979 8.28e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MLKANEBP_00980 1.6e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLKANEBP_00981 4.17e-192 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLKANEBP_00982 1.74e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLKANEBP_00983 4.04e-206 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLKANEBP_00984 4.16e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLKANEBP_00985 1.57e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MLKANEBP_00986 2.55e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLKANEBP_00987 3.95e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLKANEBP_00988 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLKANEBP_00989 4.63e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MLKANEBP_00990 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLKANEBP_00991 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLKANEBP_00992 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLKANEBP_00993 2.45e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLKANEBP_00994 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MLKANEBP_00995 5.3e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLKANEBP_00996 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLKANEBP_00997 2.5e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLKANEBP_00998 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLKANEBP_00999 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLKANEBP_01000 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLKANEBP_01001 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLKANEBP_01002 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLKANEBP_01003 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLKANEBP_01004 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MLKANEBP_01005 9.64e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLKANEBP_01006 7.15e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLKANEBP_01007 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLKANEBP_01008 1.34e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLKANEBP_01009 9.85e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLKANEBP_01010 7.21e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLKANEBP_01011 1.91e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MLKANEBP_01012 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLKANEBP_01013 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MLKANEBP_01014 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLKANEBP_01015 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLKANEBP_01016 2.09e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLKANEBP_01017 6.6e-159 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MLKANEBP_01018 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLKANEBP_01019 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLKANEBP_01020 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MLKANEBP_01021 1.16e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MLKANEBP_01025 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MLKANEBP_01026 3.5e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLKANEBP_01027 6.77e-215 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLKANEBP_01028 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLKANEBP_01029 5.11e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLKANEBP_01030 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MLKANEBP_01031 1.03e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MLKANEBP_01032 1.79e-46 yabO - - J - - - S4 domain protein
MLKANEBP_01033 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLKANEBP_01034 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLKANEBP_01035 6.58e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLKANEBP_01036 1.98e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLKANEBP_01037 1.44e-165 - - - S - - - (CBS) domain
MLKANEBP_01038 2.68e-275 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLKANEBP_01039 3.27e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLKANEBP_01040 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLKANEBP_01041 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLKANEBP_01042 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MLKANEBP_01043 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MLKANEBP_01044 9.8e-204 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLKANEBP_01045 0.0 - - - E - - - amino acid
MLKANEBP_01046 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLKANEBP_01047 4.88e-59 - - - - - - - -
MLKANEBP_01048 8.2e-68 - - - - - - - -
MLKANEBP_01049 7.47e-126 - - - - - - - -
MLKANEBP_01050 4.62e-13 - - - P - - - Voltage gated chloride channel
MLKANEBP_01051 6.74e-39 - - - K ko:K12410 - ko00000,ko01000 NAD+ binding
MLKANEBP_01052 3.18e-106 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLKANEBP_01053 5.49e-42 - - - - - - - -
MLKANEBP_01054 2.89e-44 - - - P - - - Belongs to the major facilitator superfamily
MLKANEBP_01055 2.07e-117 - - - P - - - Belongs to the major facilitator superfamily
MLKANEBP_01056 9.09e-173 XK27_07210 - - S - - - B3 4 domain
MLKANEBP_01057 7.88e-116 - - - K - - - Acetyltransferase (GNAT) domain
MLKANEBP_01058 1.16e-63 - - - S - - - Protein of unknown function (DUF3021)
MLKANEBP_01059 2.08e-96 - - - K - - - LytTr DNA-binding domain
MLKANEBP_01060 3.12e-191 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MLKANEBP_01061 7.77e-199 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_01062 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MLKANEBP_01063 3.77e-220 - - - K - - - Helix-turn-helix
MLKANEBP_01064 1.04e-173 - - - K - - - DNA-binding helix-turn-helix protein
MLKANEBP_01065 5.8e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLKANEBP_01066 2.84e-284 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MLKANEBP_01067 8.61e-139 ybbB - - S - - - Protein of unknown function (DUF1211)
MLKANEBP_01068 7.87e-207 msmR - - K - - - AraC-like ligand binding domain
MLKANEBP_01069 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLKANEBP_01070 6.32e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLKANEBP_01071 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLKANEBP_01072 1.11e-96 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLKANEBP_01073 4.39e-88 - - - S - - - Domain of unknown function (DUF1934)
MLKANEBP_01074 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLKANEBP_01075 4.88e-59 - - - - - - - -
MLKANEBP_01076 4.58e-216 - - - GK - - - ROK family
MLKANEBP_01077 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_01078 3.82e-167 yecA - - K - - - Helix-turn-helix domain, rpiR family
MLKANEBP_01079 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_01080 2.68e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLKANEBP_01081 0.0 - - - S - - - SLAP domain
MLKANEBP_01082 1.48e-114 - - - - - - - -
MLKANEBP_01083 4.55e-117 - - - S - - - SLAP domain
MLKANEBP_01084 1.4e-116 - - - S - - - SLAP domain
MLKANEBP_01085 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLKANEBP_01086 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MLKANEBP_01087 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
MLKANEBP_01088 4.9e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLKANEBP_01089 1.63e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLKANEBP_01090 2.33e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MLKANEBP_01091 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLKANEBP_01092 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MLKANEBP_01093 1.25e-142 - - - S ko:K06872 - ko00000 TPM domain
MLKANEBP_01094 2.69e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MLKANEBP_01095 2.35e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLKANEBP_01096 1.21e-146 - - - E - - - Belongs to the SOS response-associated peptidase family
MLKANEBP_01098 1.09e-148 - - - - - - - -
MLKANEBP_01099 6.92e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLKANEBP_01100 1.5e-96 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLKANEBP_01101 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MLKANEBP_01102 1.87e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01103 1.9e-256 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01104 1.92e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLKANEBP_01105 5.46e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLKANEBP_01106 8.86e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLKANEBP_01107 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLKANEBP_01108 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLKANEBP_01109 1.16e-162 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLKANEBP_01110 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MLKANEBP_01112 1.02e-74 - - - - - - - -
MLKANEBP_01113 6.28e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLKANEBP_01114 0.0 - - - S - - - Fibronectin type III domain
MLKANEBP_01115 0.0 XK27_08315 - - M - - - Sulfatase
MLKANEBP_01116 2.73e-146 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLKANEBP_01117 1.34e-259 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLKANEBP_01118 1.96e-132 - - - G - - - Aldose 1-epimerase
MLKANEBP_01119 8.51e-143 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLKANEBP_01120 1.84e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLKANEBP_01121 2.12e-176 - - - - - - - -
MLKANEBP_01122 4.62e-181 - - - - - - - -
MLKANEBP_01123 6.61e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MLKANEBP_01124 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MLKANEBP_01125 7.59e-269 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MLKANEBP_01126 2.53e-283 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLKANEBP_01128 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MLKANEBP_01129 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MLKANEBP_01130 1.51e-145 - - - - - - - -
MLKANEBP_01131 9.91e-241 - - - M - - - domain protein
MLKANEBP_01132 1.45e-280 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLKANEBP_01133 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLKANEBP_01134 5.56e-246 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MLKANEBP_01135 1.42e-215 - - - S - - - SLAP domain
MLKANEBP_01136 3.46e-53 - - - C - - - FMN binding
MLKANEBP_01138 1.53e-61 - - - - - - - -
MLKANEBP_01139 9.46e-67 - - - S - - - Domain of unknown function (DUF4160)
MLKANEBP_01140 4.02e-124 - - - S - - - Domain of unknown function (DUF4811)
MLKANEBP_01141 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MLKANEBP_01142 2.78e-98 - - - K - - - MerR HTH family regulatory protein
MLKANEBP_01143 2.43e-204 lacR - - K - - - helix_turn_helix, arabinose operon control protein
MLKANEBP_01144 6.26e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLKANEBP_01145 1.98e-200 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01146 7.19e-196 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01147 3.33e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01148 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MLKANEBP_01149 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MLKANEBP_01150 1.63e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLKANEBP_01151 8.2e-81 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MLKANEBP_01152 1.31e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MLKANEBP_01153 7.55e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MLKANEBP_01154 4.2e-147 - - - T - - - Region found in RelA / SpoT proteins
MLKANEBP_01155 1.28e-152 dltr - - K - - - response regulator
MLKANEBP_01156 5.46e-297 sptS - - T - - - Histidine kinase
MLKANEBP_01157 3.65e-272 - - - EGP - - - Major Facilitator Superfamily
MLKANEBP_01158 8.84e-93 - - - O - - - OsmC-like protein
MLKANEBP_01159 5.44e-163 - - - S - - - L-ascorbic acid biosynthetic process
MLKANEBP_01160 1.31e-165 - - - - - - - -
MLKANEBP_01162 2.05e-163 - - - S - - - Alpha beta hydrolase
MLKANEBP_01163 0.0 potE - - E - - - Amino Acid
MLKANEBP_01164 2.86e-19 - - - - - - - -
MLKANEBP_01165 4.83e-141 pncA - - Q - - - Isochorismatase family
MLKANEBP_01166 4.27e-37 - - - C - - - pentaerythritol trinitrate reductase activity
MLKANEBP_01167 4.69e-271 - - - L ko:K07496 - ko00000 TIGRFAM transposase, IS605 OrfB family
MLKANEBP_01169 9.37e-227 - - - C - - - Oxidoreductase
MLKANEBP_01170 3.07e-119 - - - - - - - -
MLKANEBP_01171 4.05e-233 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLKANEBP_01172 3.81e-58 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLKANEBP_01173 8.74e-192 - - - T - - - EAL domain
MLKANEBP_01174 1.63e-169 - - - T - - - Putative diguanylate phosphodiesterase
MLKANEBP_01175 2.26e-267 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
MLKANEBP_01178 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
MLKANEBP_01179 5.31e-206 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MLKANEBP_01181 6.71e-153 - - - S - - - GyrI-like small molecule binding domain
MLKANEBP_01182 8.85e-85 - - - S - - - ASCH domain
MLKANEBP_01183 2.97e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MLKANEBP_01184 1.77e-150 ylbE - - GM - - - NAD(P)H-binding
MLKANEBP_01185 3.88e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MLKANEBP_01186 7.81e-82 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MLKANEBP_01187 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MLKANEBP_01189 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_01190 2.66e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
MLKANEBP_01191 1.15e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MLKANEBP_01192 7.22e-161 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MLKANEBP_01193 2.87e-62 - - - - - - - -
MLKANEBP_01194 2.34e-204 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLKANEBP_01195 1.65e-66 - - - - - - - -
MLKANEBP_01196 3.89e-122 - - - K - - - acetyltransferase
MLKANEBP_01197 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLKANEBP_01198 1.86e-141 - - - O - - - Matrixin
MLKANEBP_01199 9.28e-317 eriC - - P ko:K03281 - ko00000 chloride
MLKANEBP_01200 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLKANEBP_01201 3.3e-152 - - - GM - - - NmrA-like family
MLKANEBP_01202 9.13e-153 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLKANEBP_01203 7.44e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLKANEBP_01204 2.33e-164 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLKANEBP_01205 1.71e-33 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLKANEBP_01206 1.75e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLKANEBP_01207 3.43e-235 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MLKANEBP_01208 8.15e-69 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLKANEBP_01209 1.47e-191 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLKANEBP_01210 2.85e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLKANEBP_01211 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLKANEBP_01212 2.73e-07 - - - D - - - Domain of Unknown Function (DUF1542)
MLKANEBP_01213 0.0 - - - - - - - -
MLKANEBP_01214 1.74e-192 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MLKANEBP_01215 2.43e-62 - - - - - - - -
MLKANEBP_01216 1.67e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MLKANEBP_01217 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MLKANEBP_01218 2.45e-63 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
MLKANEBP_01219 1.02e-85 - - - K - - - sequence-specific DNA binding
MLKANEBP_01220 3.5e-22 - - - - - - - -
MLKANEBP_01221 9.35e-128 - - - S - - - Bacterial PH domain
MLKANEBP_01222 4.89e-301 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_01223 3.58e-262 xylR - - GK - - - ROK family
MLKANEBP_01224 7.89e-213 - 2.7.1.85 - GK ko:K18673 - ko00000,ko01000 ROK family
MLKANEBP_01225 0.0 - 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_01226 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MLKANEBP_01227 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MLKANEBP_01228 0.0 - - - - - - - -
MLKANEBP_01229 1.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
MLKANEBP_01230 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_01231 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_01232 4.8e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MLKANEBP_01233 1.75e-227 lipA - - I - - - Carboxylesterase family
MLKANEBP_01234 4.22e-211 - - - S - - - Membrane
MLKANEBP_01236 1.52e-243 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLKANEBP_01237 3.04e-198 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MLKANEBP_01238 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MLKANEBP_01239 3.88e-196 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
MLKANEBP_01240 7.38e-127 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_01241 9.58e-80 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_01242 7.45e-09 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_01243 9.64e-141 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MLKANEBP_01244 4.41e-137 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MLKANEBP_01245 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MLKANEBP_01246 3.98e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLKANEBP_01247 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MLKANEBP_01248 3.54e-192 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLKANEBP_01249 4.8e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MLKANEBP_01250 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MLKANEBP_01251 3.69e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLKANEBP_01252 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLKANEBP_01253 2.57e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MLKANEBP_01254 1.28e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLKANEBP_01255 5.91e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLKANEBP_01256 5.86e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLKANEBP_01257 3.76e-48 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLKANEBP_01258 1.84e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLKANEBP_01259 1.52e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MLKANEBP_01260 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MLKANEBP_01261 2.88e-105 - - - S - - - ASCH
MLKANEBP_01262 2.53e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MLKANEBP_01263 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLKANEBP_01264 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLKANEBP_01265 1.08e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLKANEBP_01266 4.61e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLKANEBP_01267 9.79e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MLKANEBP_01268 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLKANEBP_01269 1.37e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLKANEBP_01270 5.27e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MLKANEBP_01271 1.42e-104 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MLKANEBP_01272 1.5e-68 - - - - - - - -
MLKANEBP_01273 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MLKANEBP_01274 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
MLKANEBP_01275 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MLKANEBP_01276 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLKANEBP_01277 3.16e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLKANEBP_01278 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLKANEBP_01279 1.43e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01280 8.73e-234 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01281 1.49e-225 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_01282 5.84e-202 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01283 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_01284 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_01286 1.36e-241 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MLKANEBP_01287 1.67e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MLKANEBP_01288 1.18e-225 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MLKANEBP_01289 2.86e-85 - - - S - - - Domain of unknown function (DUF956)
MLKANEBP_01290 7.93e-206 - - - K - - - Transcriptional regulator
MLKANEBP_01291 3.62e-89 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MLKANEBP_01292 2.27e-315 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLKANEBP_01293 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MLKANEBP_01294 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLKANEBP_01295 1.47e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLKANEBP_01296 1.63e-175 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MLKANEBP_01297 8.15e-94 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MLKANEBP_01298 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MLKANEBP_01299 0.0 - - - S - - - TerB-C domain
MLKANEBP_01300 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
MLKANEBP_01301 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MLKANEBP_01302 4.47e-81 - - - - - - - -
MLKANEBP_01303 1.14e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MLKANEBP_01304 8.42e-187 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MLKANEBP_01306 0.0 - - - L - - - Type III restriction enzyme, res subunit
MLKANEBP_01307 0.0 - - - S - - - AAA ATPase domain
MLKANEBP_01308 4.51e-59 - - - S - - - AAA ATPase domain
MLKANEBP_01309 1.46e-191 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
MLKANEBP_01310 8.37e-161 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MLKANEBP_01312 8.66e-76 - - - - - - - -
MLKANEBP_01313 2.66e-270 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLKANEBP_01315 3.69e-244 - - - EP - - - Plasmid replication protein
MLKANEBP_01316 6.89e-06 - - - - - - - -
MLKANEBP_01317 1.14e-295 - - - L - - - Belongs to the 'phage' integrase family
MLKANEBP_01318 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MLKANEBP_01319 3.99e-45 - - - - - - - -
MLKANEBP_01320 3.99e-88 - - - - - - - -
MLKANEBP_01321 1.48e-219 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MLKANEBP_01322 2.6e-19 - - - - - - - -
MLKANEBP_01323 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_01324 4.35e-207 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MLKANEBP_01325 2.62e-111 - - - M - - - LysM domain protein
MLKANEBP_01326 3.81e-253 - - - D - - - nuclear chromosome segregation
MLKANEBP_01327 1e-142 - - - G - - - Phosphoglycerate mutase family
MLKANEBP_01328 2.57e-139 - - - G - - - Histidine phosphatase superfamily (branch 1)
MLKANEBP_01329 9.82e-156 - - - G - - - Antibiotic biosynthesis monooxygenase
MLKANEBP_01330 9.11e-69 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLKANEBP_01331 7.11e-236 lacI - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLKANEBP_01332 0.0 - - - G ko:K02027,ko:K10120 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLKANEBP_01333 1.78e-209 - - - P ko:K10121 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MLKANEBP_01334 2.93e-199 msmG - - G ko:K02026,ko:K10122 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01335 4.18e-292 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
MLKANEBP_01336 2.07e-234 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01337 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MLKANEBP_01338 3.18e-92 - - - EGP - - - Major Facilitator
MLKANEBP_01340 3.91e-226 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MLKANEBP_01341 0.0 slpX - - S - - - SLAP domain
MLKANEBP_01344 5.81e-272 - - - - - - - -
MLKANEBP_01345 1.33e-160 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MLKANEBP_01346 2.13e-92 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MLKANEBP_01347 1.39e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLKANEBP_01348 1.85e-264 - - - M - - - Glycosyl transferases group 1
MLKANEBP_01349 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLKANEBP_01350 5.7e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLKANEBP_01351 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLKANEBP_01352 3.89e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLKANEBP_01353 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLKANEBP_01354 8.44e-177 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MLKANEBP_01355 6.32e-83 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MLKANEBP_01357 1.02e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MLKANEBP_01358 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MLKANEBP_01359 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLKANEBP_01360 7.29e-267 camS - - S - - - sex pheromone
MLKANEBP_01361 4.46e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLKANEBP_01362 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLKANEBP_01363 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLKANEBP_01364 2.37e-220 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MLKANEBP_01365 2.4e-143 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLKANEBP_01366 4.94e-75 - - - - - - - -
MLKANEBP_01367 1.28e-310 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MLKANEBP_01368 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLKANEBP_01369 4.2e-30 - - - - - - - -
MLKANEBP_01370 1.48e-82 - - - - - - - -
MLKANEBP_01371 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MLKANEBP_01372 5.51e-46 - - - C - - - Heavy-metal-associated domain
MLKANEBP_01373 1.05e-124 dpsB - - P - - - Belongs to the Dps family
MLKANEBP_01374 9.1e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MLKANEBP_01375 5.16e-146 ung2 - - L - - - Uracil-DNA glycosylase
MLKANEBP_01376 3.15e-62 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
MLKANEBP_01377 2.43e-76 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
MLKANEBP_01378 2.98e-246 - - - L ko:K06400 - ko00000 Recombinase
MLKANEBP_01379 3.28e-122 - - - L - - - Resolvase, N terminal domain
MLKANEBP_01380 9.05e-231 - - - L - - - Recombinase zinc beta ribbon domain
MLKANEBP_01381 3.49e-123 - - - K - - - Acetyltransferase (GNAT) domain
MLKANEBP_01386 0.0 qacA - - EGP - - - Major Facilitator
MLKANEBP_01387 1.88e-174 - - - S - - - CAAX protease self-immunity
MLKANEBP_01388 1.25e-118 - - - K - - - Bacterial regulatory proteins, tetR family
MLKANEBP_01389 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MLKANEBP_01390 3.79e-101 - - - K - - - acetyltransferase
MLKANEBP_01391 1.36e-205 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MLKANEBP_01392 5.13e-141 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MLKANEBP_01393 5.81e-165 XK27_08575 - - V ko:K06148 - ko00000,ko02000 cysteine transport
MLKANEBP_01394 5.36e-305 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MLKANEBP_01395 1.39e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLKANEBP_01396 3.27e-110 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLKANEBP_01397 2.03e-67 - 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MLKANEBP_01398 0.0 qacA - - EGP - - - Major Facilitator
MLKANEBP_01399 3.81e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MLKANEBP_01400 1.11e-212 - - - S ko:K07088 - ko00000 Membrane transport protein
MLKANEBP_01401 7.56e-267 pepA - - E - - - M42 glutamyl aminopeptidase
MLKANEBP_01402 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MLKANEBP_01403 1.4e-188 - - - - - - - -
MLKANEBP_01404 2.22e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLKANEBP_01405 6.57e-102 - - - K - - - Transcriptional regulator, MarR family
MLKANEBP_01406 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01407 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MLKANEBP_01408 8.88e-132 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MLKANEBP_01409 1.92e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MLKANEBP_01410 2.39e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01411 4.3e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_01412 1.43e-136 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_01413 8.28e-143 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_01414 3.66e-224 - - - S - - - Protein of unknown function (DUF2974)
MLKANEBP_01415 2.75e-95 - - - - - - - -
MLKANEBP_01416 5.02e-313 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLKANEBP_01417 5.34e-211 - - - C - - - Domain of unknown function (DUF4931)
MLKANEBP_01418 9.2e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLKANEBP_01419 1.56e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MLKANEBP_01420 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MLKANEBP_01421 3.51e-223 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MLKANEBP_01422 1.98e-175 gntR - - K - - - UbiC transcription regulator-associated domain protein
MLKANEBP_01423 1.81e-28 - - - - - - - -
MLKANEBP_01424 5.7e-146 - - - - - - - -
MLKANEBP_01425 0.0 - - - V - - - ABC transporter transmembrane region
MLKANEBP_01426 2.07e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLKANEBP_01427 1.21e-93 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MLKANEBP_01428 3.85e-143 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MLKANEBP_01429 8.25e-221 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MLKANEBP_01430 7.73e-79 - - - S - - - Enterocin A Immunity
MLKANEBP_01431 3.4e-178 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MLKANEBP_01432 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MLKANEBP_01433 2.25e-206 - - - S - - - Phospholipase, patatin family
MLKANEBP_01434 7.37e-293 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLKANEBP_01435 8.04e-187 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MLKANEBP_01436 5.93e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLKANEBP_01437 1.35e-196 - - - S - - - hydrolase
MLKANEBP_01438 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MLKANEBP_01439 3.69e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MLKANEBP_01440 2.25e-105 - - - - - - - -
MLKANEBP_01441 5.61e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MLKANEBP_01442 1.51e-53 - - - - - - - -
MLKANEBP_01443 4.33e-154 - - - C - - - nitroreductase
MLKANEBP_01444 0.0 yhdP - - S - - - Transporter associated domain
MLKANEBP_01445 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLKANEBP_01446 3.27e-294 - - - E ko:K03294 - ko00000 amino acid
MLKANEBP_01447 9.79e-168 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLKANEBP_01448 2.35e-269 yfmL - - L - - - DEAD DEAH box helicase
MLKANEBP_01449 6.86e-311 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_01452 6.71e-121 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLKANEBP_01453 2.52e-84 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MLKANEBP_01454 1.63e-175 - - - L ko:K07483 - ko00000 transposase activity
MLKANEBP_01455 1.34e-298 - - - L - - - COG3547 Transposase and inactivated derivatives
MLKANEBP_01456 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MLKANEBP_01457 1.23e-255 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MLKANEBP_01458 1.86e-287 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
MLKANEBP_01459 7.58e-244 XK27_01805 - - M - - - Glycosyltransferase like family 2
MLKANEBP_01460 2.89e-150 - - - M - - - transferase activity, transferring glycosyl groups
MLKANEBP_01461 2.65e-215 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MLKANEBP_01462 4.02e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
MLKANEBP_01463 1.77e-159 epsE2 - - M - - - Bacterial sugar transferase
MLKANEBP_01464 7.21e-190 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MLKANEBP_01465 4.87e-165 ywqD - - D - - - Capsular exopolysaccharide family
MLKANEBP_01466 1.01e-193 epsB - - M - - - biosynthesis protein
MLKANEBP_01467 5.44e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLKANEBP_01468 1.42e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLKANEBP_01469 5.52e-241 - - - S - - - Cysteine-rich secretory protein family
MLKANEBP_01470 0.0 - - - M - - - Mycoplasma protein of unknown function, DUF285
MLKANEBP_01471 1.4e-204 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MLKANEBP_01472 2.99e-176 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MLKANEBP_01473 7.09e-125 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MLKANEBP_01474 6.94e-110 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
MLKANEBP_01475 2.96e-56 - - - - - - - -
MLKANEBP_01476 0.0 - - - S - - - O-antigen ligase like membrane protein
MLKANEBP_01477 4.7e-143 - - - - - - - -
MLKANEBP_01478 7.02e-103 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MLKANEBP_01479 2.71e-233 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLKANEBP_01480 1.36e-105 - - - - - - - -
MLKANEBP_01481 3.7e-175 - - - S - - - Peptidase_C39 like family
MLKANEBP_01482 1.47e-70 yitW - - S - - - Iron-sulfur cluster assembly protein
MLKANEBP_01483 1.08e-62 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MLKANEBP_01484 1.64e-47 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MLKANEBP_01485 4.44e-110 - - - S - - - Threonine/Serine exporter, ThrE
MLKANEBP_01486 3.12e-175 - - - S - - - Putative threonine/serine exporter
MLKANEBP_01487 0.0 - - - S - - - ABC transporter
MLKANEBP_01488 3.08e-81 - - - - - - - -
MLKANEBP_01489 2.7e-59 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLKANEBP_01490 5.01e-293 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLKANEBP_01491 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MLKANEBP_01492 9.86e-59 - - - P ko:K03449 - ko00000,ko02000 transmembrane transport
MLKANEBP_01493 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MLKANEBP_01494 1.04e-82 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MLKANEBP_01495 6.99e-174 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MLKANEBP_01496 6.65e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLKANEBP_01497 1.79e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLKANEBP_01498 7.83e-60 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MLKANEBP_01499 3e-98 - - - K - - - LytTr DNA-binding domain
MLKANEBP_01500 4.7e-64 - - - S - - - Protein of unknown function (DUF3021)
MLKANEBP_01501 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MLKANEBP_01502 1.31e-216 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MLKANEBP_01503 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MLKANEBP_01504 6.57e-252 - - - S - - - Fic/DOC family
MLKANEBP_01505 1.22e-274 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MLKANEBP_01506 1.6e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01507 2.89e-12 - - - - - - - -
MLKANEBP_01508 4.14e-89 - - - - - - - -
MLKANEBP_01509 6.68e-35 - - - - - - - -
MLKANEBP_01510 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MLKANEBP_01511 9.7e-116 - - - - - - - -
MLKANEBP_01512 2.26e-29 - - - - - - - -
MLKANEBP_01517 1.21e-275 blpT - - - - - - -
MLKANEBP_01518 3.21e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MLKANEBP_01519 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MLKANEBP_01522 7.63e-190 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MLKANEBP_01523 4.67e-297 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLKANEBP_01524 2e-06 - - - - - - - -
MLKANEBP_01527 2.6e-141 - - - - - - - -
MLKANEBP_01529 2.71e-136 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLKANEBP_01530 5.21e-275 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLKANEBP_01531 2.62e-50 - - - S - - - Enterocin A Immunity
MLKANEBP_01532 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MLKANEBP_01533 9.17e-37 - - - - - - - -
MLKANEBP_01534 1.47e-45 - - - - - - - -
MLKANEBP_01535 1.4e-69 - - - S - - - Enterocin A Immunity
MLKANEBP_01536 5.63e-64 - - - S - - - Enterocin A Immunity
MLKANEBP_01537 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLKANEBP_01538 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLKANEBP_01539 9.58e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
MLKANEBP_01540 1.44e-157 vanR - - K - - - response regulator
MLKANEBP_01541 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLKANEBP_01542 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01543 1.55e-177 - - - S - - - Protein of unknown function (DUF1129)
MLKANEBP_01544 1.39e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLKANEBP_01545 2.22e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MLKANEBP_01546 2.05e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLKANEBP_01547 4.1e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MLKANEBP_01548 2.79e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLKANEBP_01549 3.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MLKANEBP_01550 8.5e-105 cvpA - - S - - - Colicin V production protein
MLKANEBP_01551 6.64e-233 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLKANEBP_01552 9.1e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLKANEBP_01553 6.34e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLKANEBP_01554 4.14e-126 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLKANEBP_01555 2.15e-144 - - - K - - - WHG domain
MLKANEBP_01556 1.59e-49 - - - - - - - -
MLKANEBP_01557 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLKANEBP_01558 3.26e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01559 1.43e-231 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MLKANEBP_01560 1.45e-124 - - - K - - - Bacterial regulatory proteins, tetR family
MLKANEBP_01561 9.98e-146 - - - G - - - phosphoglycerate mutase
MLKANEBP_01562 1.19e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MLKANEBP_01563 4.33e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MLKANEBP_01564 3.44e-153 - - - - - - - -
MLKANEBP_01565 3.08e-204 - - - C - - - Domain of unknown function (DUF4931)
MLKANEBP_01566 1.71e-282 - - - S - - - Putative peptidoglycan binding domain
MLKANEBP_01567 2.13e-36 - - - - - - - -
MLKANEBP_01568 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MLKANEBP_01569 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MLKANEBP_01570 7.67e-80 lysM - - M - - - LysM domain
MLKANEBP_01571 9.68e-226 - - - - - - - -
MLKANEBP_01572 3e-133 - - - EGP - - - Major Facilitator Superfamily
MLKANEBP_01573 8.59e-148 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MLKANEBP_01575 1.97e-280 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MLKANEBP_01576 1.53e-118 ymdB - - S - - - Macro domain protein
MLKANEBP_01577 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
MLKANEBP_01580 2.49e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_01581 2.56e-110 - - - - - - - -
MLKANEBP_01582 8.05e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLKANEBP_01583 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01584 1.35e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLKANEBP_01585 6e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLKANEBP_01586 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLKANEBP_01587 1.28e-131 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLKANEBP_01588 1.47e-144 - - - S - - - SNARE associated Golgi protein
MLKANEBP_01589 1.84e-196 - - - I - - - alpha/beta hydrolase fold
MLKANEBP_01590 4.92e-207 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MLKANEBP_01591 3.62e-121 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MLKANEBP_01592 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLKANEBP_01593 0.0 - - - M - - - Rib/alpha-like repeat
MLKANEBP_01594 0.0 - - - M - - - Rib/alpha-like repeat
MLKANEBP_01595 6.9e-220 - - - - - - - -
MLKANEBP_01596 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MLKANEBP_01597 1.8e-124 yobS - - K - - - Bacterial regulatory proteins, tetR family
MLKANEBP_01598 2.62e-198 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MLKANEBP_01599 7.19e-202 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLKANEBP_01600 2.47e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLKANEBP_01601 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
MLKANEBP_01602 1.68e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLKANEBP_01603 1.24e-197 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MLKANEBP_01604 9.81e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLKANEBP_01605 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLKANEBP_01606 4.53e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MLKANEBP_01607 4e-234 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MLKANEBP_01608 4.72e-200 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MLKANEBP_01609 7.21e-150 yviA - - S - - - Protein of unknown function (DUF421)
MLKANEBP_01610 9.54e-97 - - - S - - - Protein of unknown function (DUF3290)
MLKANEBP_01611 0.0 - - - M - - - domain protein
MLKANEBP_01612 3.05e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MLKANEBP_01613 0.0 - - - - - - - -
MLKANEBP_01614 7.95e-64 - - - - - - - -
MLKANEBP_01615 9.1e-184 - - - S - - - PAS domain
MLKANEBP_01616 3.75e-111 - - - V - - - ABC transporter transmembrane region
MLKANEBP_01617 1.85e-246 - - - V - - - ABC transporter transmembrane region
MLKANEBP_01618 5.44e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLKANEBP_01619 2.91e-164 - - - T - - - Transcriptional regulatory protein, C terminal
MLKANEBP_01620 1.47e-310 - - - T - - - GHKL domain
MLKANEBP_01621 2.36e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MLKANEBP_01622 1.34e-131 - - - S - - - Peptidase propeptide and YPEB domain
MLKANEBP_01623 4.9e-100 yybA - - K - - - Transcriptional regulator
MLKANEBP_01624 3.59e-123 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLKANEBP_01625 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLKANEBP_01626 2.28e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MLKANEBP_01627 9.2e-130 - - - S - - - Peptidase propeptide and YPEB domain
MLKANEBP_01628 8.57e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLKANEBP_01629 3.51e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MLKANEBP_01630 1.68e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
MLKANEBP_01631 1.25e-106 yjcF - - S - - - Acetyltransferase (GNAT) domain
MLKANEBP_01632 2.71e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MLKANEBP_01633 1.29e-140 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MLKANEBP_01634 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLKANEBP_01635 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLKANEBP_01636 1.69e-160 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MLKANEBP_01637 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
MLKANEBP_01638 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MLKANEBP_01639 3.02e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01640 7.62e-308 - - - S - - - response to antibiotic
MLKANEBP_01641 8.94e-26 - - - - - - - -
MLKANEBP_01642 2.15e-50 - - - - - - - -
MLKANEBP_01643 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLKANEBP_01644 3.66e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MLKANEBP_01645 3.45e-64 - - - - - - - -
MLKANEBP_01646 1.25e-22 - - - - - - - -
MLKANEBP_01647 1.35e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MLKANEBP_01648 7.07e-178 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MLKANEBP_01649 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MLKANEBP_01650 8.44e-201 - - - - - - - -
MLKANEBP_01651 1.6e-119 - - - - - - - -
MLKANEBP_01652 3.39e-138 - - - K ko:K06977 - ko00000 acetyltransferase
MLKANEBP_01655 0.0 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
MLKANEBP_01656 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
MLKANEBP_01657 5.59e-250 - - - S - - - Domain of unknown function (DUF4767)
MLKANEBP_01658 1.56e-256 - - - S - - - Membrane
MLKANEBP_01659 1.71e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLKANEBP_01660 7.86e-240 - - - K - - - helix_turn_helix, arabinose operon control protein
MLKANEBP_01661 3.86e-239 - - - K - - - helix_turn_helix, arabinose operon control protein
MLKANEBP_01662 1.96e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
MLKANEBP_01663 1.61e-134 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MLKANEBP_01664 2.88e-107 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MLKANEBP_01665 1.24e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLKANEBP_01666 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_01667 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLKANEBP_01668 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLKANEBP_01669 4.37e-205 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MLKANEBP_01670 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
MLKANEBP_01671 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MLKANEBP_01672 4.05e-119 - - - - - - - -
MLKANEBP_01673 6.91e-235 - - - - - - - -
MLKANEBP_01674 1.16e-175 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
MLKANEBP_01675 7.66e-181 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
MLKANEBP_01682 1.31e-211 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLKANEBP_01683 3.53e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLKANEBP_01684 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
MLKANEBP_01685 6.91e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MLKANEBP_01686 1.63e-152 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MLKANEBP_01687 1.19e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLKANEBP_01688 1.25e-204 - - - S - - - Aldo/keto reductase family
MLKANEBP_01689 4.74e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLKANEBP_01690 9.19e-266 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLKANEBP_01691 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MLKANEBP_01692 9.41e-257 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MLKANEBP_01693 1.21e-236 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MLKANEBP_01694 2.61e-133 - - - S - - - ECF transporter, substrate-specific component
MLKANEBP_01695 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01696 3.39e-253 - - - S - - - DUF218 domain
MLKANEBP_01697 2.41e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLKANEBP_01698 1.4e-88 - - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_01699 5.7e-125 - - - M - - - CHAP domain
MLKANEBP_01700 1.57e-197 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MLKANEBP_01701 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MLKANEBP_01702 2.82e-105 - - - S - - - Putative adhesin
MLKANEBP_01703 4.69e-262 napA - - P - - - Sodium/hydrogen exchanger family
MLKANEBP_01704 0.0 cadA - - P - - - P-type ATPase
MLKANEBP_01705 1.97e-107 ykuL - - S - - - (CBS) domain
MLKANEBP_01706 8.03e-278 - - - S - - - Membrane
MLKANEBP_01707 2.18e-53 - - - - - - - -
MLKANEBP_01708 2.17e-25 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MLKANEBP_01709 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLKANEBP_01710 3.35e-310 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MLKANEBP_01711 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLKANEBP_01712 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLKANEBP_01713 3.4e-228 pbpX2 - - V - - - Beta-lactamase
MLKANEBP_01714 2.86e-81 - - - - - - - -
MLKANEBP_01715 9.09e-164 - - - S - - - Protein of unknown function (DUF975)
MLKANEBP_01716 9.26e-222 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MLKANEBP_01717 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLKANEBP_01718 5.63e-49 - - - - - - - -
MLKANEBP_01719 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MLKANEBP_01720 8.01e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01721 1e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLKANEBP_01722 4.24e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLKANEBP_01723 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
MLKANEBP_01724 1.07e-150 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLKANEBP_01725 0.0 - - - L - - - Transposase
MLKANEBP_01726 8.71e-157 - - - - - - - -
MLKANEBP_01727 4.27e-293 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLKANEBP_01728 1.84e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
MLKANEBP_01729 1.4e-180 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MLKANEBP_01730 1e-305 - - - E - - - amino acid
MLKANEBP_01731 1.27e-70 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
MLKANEBP_01732 1.75e-10 - - - - - - - -
MLKANEBP_01733 6.09e-152 - - - K - - - Rhodanese Homology Domain
MLKANEBP_01734 1.23e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLKANEBP_01735 6.65e-153 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MLKANEBP_01736 4.88e-225 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MLKANEBP_01737 1.69e-259 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MLKANEBP_01740 2.84e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLKANEBP_01741 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLKANEBP_01742 1.14e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLKANEBP_01743 6.33e-74 - - - - - - - -
MLKANEBP_01744 7.08e-137 - - - - - - - -
MLKANEBP_01745 1.41e-209 yicL - - EG - - - EamA-like transporter family
MLKANEBP_01746 1.03e-211 - - - EG - - - EamA-like transporter family
MLKANEBP_01747 8.16e-212 - - - EG - - - EamA-like transporter family
MLKANEBP_01748 1.96e-108 - - - M - - - NlpC/P60 family
MLKANEBP_01749 1.91e-171 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MLKANEBP_01750 9.67e-220 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MLKANEBP_01751 1.23e-83 - - - S - - - Protein conserved in bacteria
MLKANEBP_01752 6.65e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLKANEBP_01753 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLKANEBP_01754 1.06e-20 - - - - - - - -
MLKANEBP_01755 4.8e-99 - - - - - - - -
MLKANEBP_01756 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MLKANEBP_01757 7.79e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLKANEBP_01758 7.43e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
MLKANEBP_01759 1.82e-276 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLKANEBP_01760 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MLKANEBP_01761 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MLKANEBP_01762 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MLKANEBP_01763 1.23e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MLKANEBP_01764 9.9e-240 purR13 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
MLKANEBP_01765 5.73e-202 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
MLKANEBP_01766 2.68e-225 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MLKANEBP_01767 2.22e-09 glpK3 2.7.1.30 - G ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 FGGY family of carbohydrate kinases, C-terminal domain
MLKANEBP_01768 1.71e-226 glpK3 2.7.1.30 - G ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 FGGY family of carbohydrate kinases, C-terminal domain
MLKANEBP_01769 1.86e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLKANEBP_01770 8.07e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MLKANEBP_01773 2.37e-210 - - - - - - - -
MLKANEBP_01774 5.77e-214 - - - - - - - -
MLKANEBP_01775 7.72e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01776 7.05e-171 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MLKANEBP_01777 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MLKANEBP_01778 1.71e-301 ynbB - - P - - - aluminum resistance
MLKANEBP_01779 8.27e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLKANEBP_01780 1.48e-90 yqhL - - P - - - Rhodanese-like protein
MLKANEBP_01781 4.01e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MLKANEBP_01782 4.62e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MLKANEBP_01783 3.23e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLKANEBP_01784 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLKANEBP_01785 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLKANEBP_01786 0.0 - - - S - - - membrane
MLKANEBP_01787 2.46e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MLKANEBP_01788 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLKANEBP_01789 1.06e-69 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MLKANEBP_01790 3.51e-17 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MLKANEBP_01791 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLKANEBP_01792 1.6e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MLKANEBP_01793 3.63e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLKANEBP_01794 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLKANEBP_01795 2.59e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLKANEBP_01796 1.24e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MLKANEBP_01797 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLKANEBP_01798 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MLKANEBP_01799 1.89e-209 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLKANEBP_01800 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLKANEBP_01801 6.08e-164 csrR - - K - - - response regulator
MLKANEBP_01802 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MLKANEBP_01803 9.35e-275 ylbM - - S - - - Belongs to the UPF0348 family
MLKANEBP_01804 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLKANEBP_01805 4.06e-145 yqeK - - H - - - Hydrolase, HD family
MLKANEBP_01806 8.11e-159 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLKANEBP_01807 4.26e-273 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MLKANEBP_01808 1.66e-120 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MLKANEBP_01809 4.78e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MLKANEBP_01810 8.82e-241 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MLKANEBP_01811 4.31e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLKANEBP_01812 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MLKANEBP_01813 9.48e-95 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLKANEBP_01814 1.92e-118 - - - - - - - -
MLKANEBP_01815 1.39e-92 - - - S - - - Protein of unknown function (DUF3021)
MLKANEBP_01816 2.67e-96 - - - K - - - LytTr DNA-binding domain
MLKANEBP_01817 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLKANEBP_01818 5.35e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MLKANEBP_01819 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MLKANEBP_01820 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLKANEBP_01821 5.52e-139 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLKANEBP_01822 6.72e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLKANEBP_01823 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLKANEBP_01824 0.0 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MLKANEBP_01825 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MLKANEBP_01826 3.61e-144 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLKANEBP_01827 3.52e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MLKANEBP_01828 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLKANEBP_01829 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLKANEBP_01830 1.15e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLKANEBP_01831 1.88e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLKANEBP_01832 1.24e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MLKANEBP_01833 1.85e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLKANEBP_01834 7.36e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLKANEBP_01835 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MLKANEBP_01836 1.9e-160 - - - C - - - Flavodoxin
MLKANEBP_01837 5.58e-192 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MLKANEBP_01838 2.68e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MLKANEBP_01839 2.76e-249 - - - S - - - Bacteriocin helveticin-J
MLKANEBP_01840 0.0 - - - M - - - Peptidase family M1 domain
MLKANEBP_01841 2.45e-227 - - - S - - - SLAP domain
MLKANEBP_01842 4.2e-75 - - - K - - - helix_turn_helix, mercury resistance
MLKANEBP_01843 1.37e-58 - - - K - - - helix_turn_helix, mercury resistance
MLKANEBP_01844 4.08e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLKANEBP_01845 3.14e-226 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLKANEBP_01846 8.04e-168 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLKANEBP_01847 3.51e-209 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MLKANEBP_01848 8.03e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLKANEBP_01849 2.47e-32 - - - - - - - -
MLKANEBP_01850 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MLKANEBP_01851 9.55e-83 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MLKANEBP_01852 1.77e-85 - - - S - - - Cupredoxin-like domain
MLKANEBP_01853 1.09e-65 - - - S - - - Cupredoxin-like domain
MLKANEBP_01854 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLKANEBP_01855 2.91e-234 - - - S - - - DUF218 domain
MLKANEBP_01856 6.11e-168 - - - S - - - Mitochondrial biogenesis AIM24
MLKANEBP_01857 6.65e-153 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MLKANEBP_01858 1.78e-26 - - - - - - - -
MLKANEBP_01859 5.17e-273 - - - - - - - -
MLKANEBP_01860 0.0 eriC - - P ko:K03281 - ko00000 chloride
MLKANEBP_01861 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLKANEBP_01862 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLKANEBP_01863 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLKANEBP_01864 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLKANEBP_01865 2.31e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLKANEBP_01866 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLKANEBP_01867 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MLKANEBP_01868 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLKANEBP_01869 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLKANEBP_01870 6.15e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MLKANEBP_01871 3.1e-269 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLKANEBP_01872 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLKANEBP_01873 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLKANEBP_01874 9.55e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MLKANEBP_01875 8.43e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLKANEBP_01876 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLKANEBP_01877 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MLKANEBP_01878 6.96e-100 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLKANEBP_01879 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MLKANEBP_01880 1e-220 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
MLKANEBP_01881 1.96e-225 degV1 - - S - - - DegV family
MLKANEBP_01882 1.09e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MLKANEBP_01883 1.38e-33 - - - S - - - CsbD-like
MLKANEBP_01884 1.47e-41 - - - S - - - Transglycosylase associated protein
MLKANEBP_01885 3.58e-303 - - - I - - - Protein of unknown function (DUF2974)
MLKANEBP_01887 7.47e-133 cadD - - P - - - Cadmium resistance transporter
MLKANEBP_01888 2.41e-77 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MLKANEBP_01889 2.93e-235 - - - - - - - -
MLKANEBP_01890 1.08e-71 - - - - - - - -
MLKANEBP_01891 7.23e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLKANEBP_01892 4.15e-120 - - - - - - - -
MLKANEBP_01893 1.16e-234 - - - EP - - - Plasmid replication protein
MLKANEBP_01894 1.45e-42 - - - - - - - -
MLKANEBP_01895 4.19e-182 - - - L - - - Belongs to the 'phage' integrase family
MLKANEBP_01896 3.32e-98 - - - L - - - Belongs to the 'phage' integrase family
MLKANEBP_01897 4.37e-43 - - - - - - - -
MLKANEBP_01898 4.41e-92 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
MLKANEBP_01899 1.63e-27 - - - S - - - Protein of unknown function (DUF3923)
MLKANEBP_01902 2.01e-205 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
MLKANEBP_01903 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLKANEBP_01904 5.78e-208 - - - S - - - LPXTG cell wall anchor motif
MLKANEBP_01905 4.34e-45 - - - S - - - LPXTG cell wall anchor motif
MLKANEBP_01906 1.4e-196 - - - S - - - Putative ABC-transporter type IV
MLKANEBP_01907 4.62e-122 - - - S - - - Cob(I)alamin adenosyltransferase
MLKANEBP_01908 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MLKANEBP_01909 9.95e-75 - - - S - - - Domain of unknown function (DUF4430)
MLKANEBP_01910 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MLKANEBP_01911 2e-223 ydbI - - K - - - AI-2E family transporter
MLKANEBP_01912 2.37e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
MLKANEBP_01913 9.67e-22 - - - - - - - -
MLKANEBP_01914 2.79e-313 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MLKANEBP_01915 6.35e-69 - - - - - - - -
MLKANEBP_01916 8.29e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLKANEBP_01917 3.51e-170 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLKANEBP_01918 3.82e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MLKANEBP_01919 1.29e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLKANEBP_01920 0.0 fusA1 - - J - - - elongation factor G
MLKANEBP_01921 1.15e-194 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLKANEBP_01922 9.66e-41 - - - S - - - endonuclease exonuclease phosphatase family protein
MLKANEBP_01923 1.63e-172 - - - S - - - endonuclease exonuclease phosphatase family protein
MLKANEBP_01924 8.28e-15 - - - S - - - interspecies interaction between organisms
MLKANEBP_01925 5.27e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLKANEBP_01926 3.08e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLKANEBP_01927 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MLKANEBP_01928 0.0 - - - L - - - Helicase C-terminal domain protein
MLKANEBP_01929 3.12e-273 pbpX1 - - V - - - Beta-lactamase
MLKANEBP_01930 6.19e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)