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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MECOMPHF_00001	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MECOMPHF_00002	1.43e-134	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MECOMPHF_00003	2.85e-265	pbpX1	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_00004	5.21e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MECOMPHF_00005	1.24e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MECOMPHF_00006	5.66e-184	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MECOMPHF_00007	6.58e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MECOMPHF_00008	4.87e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MECOMPHF_00009	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MECOMPHF_00010	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MECOMPHF_00011	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MECOMPHF_00012	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MECOMPHF_00013	6.81e-194	potE	-	-	E	-	-	-	Amino Acid
MECOMPHF_00014	1.08e-54	potE	-	-	E	-	-	-	Amino Acid
MECOMPHF_00015	7.88e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MECOMPHF_00016	1.71e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MECOMPHF_00017	2.78e-279	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MECOMPHF_00018	2.35e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MECOMPHF_00019	1.19e-194	-	-	-	-	-	-	-	-
MECOMPHF_00020	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MECOMPHF_00021	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MECOMPHF_00022	4.42e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MECOMPHF_00023	2.46e-224	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MECOMPHF_00024	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MECOMPHF_00025	1.15e-128	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MECOMPHF_00026	6.48e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MECOMPHF_00027	3.35e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MECOMPHF_00028	6.08e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MECOMPHF_00029	7e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MECOMPHF_00030	4.04e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MECOMPHF_00031	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MECOMPHF_00032	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MECOMPHF_00033	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MECOMPHF_00034	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MECOMPHF_00035	1.83e-37	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MECOMPHF_00037	4.67e-105	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MECOMPHF_00038	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MECOMPHF_00039	1.1e-145	-	-	-	S	-	-	-	repeat protein
MECOMPHF_00040	5.5e-162	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MECOMPHF_00041	1.14e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MECOMPHF_00042	2.01e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MECOMPHF_00043	5.65e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MECOMPHF_00044	6.87e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MECOMPHF_00045	2.59e-56	-	-	-	-	-	-	-	-
MECOMPHF_00046	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MECOMPHF_00047	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MECOMPHF_00048	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MECOMPHF_00049	1.44e-164	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MECOMPHF_00050	1.34e-190	ylmH	-	-	S	-	-	-	S4 domain protein
MECOMPHF_00051	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MECOMPHF_00052	5.81e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MECOMPHF_00053	6.3e-267	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MECOMPHF_00054	1.39e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MECOMPHF_00055	1.28e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MECOMPHF_00056	1.72e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MECOMPHF_00057	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MECOMPHF_00058	3.96e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MECOMPHF_00059	4.54e-57	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MECOMPHF_00060	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MECOMPHF_00061	3.79e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MECOMPHF_00062	1.15e-234	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MECOMPHF_00063	9.52e-44	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MECOMPHF_00064	4.37e-27	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MECOMPHF_00065	4.46e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MECOMPHF_00066	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MECOMPHF_00067	2.4e-125	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MECOMPHF_00068	8.63e-191	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MECOMPHF_00069	1.22e-227	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MECOMPHF_00070	3.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MECOMPHF_00071	1.76e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MECOMPHF_00072	2.64e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MECOMPHF_00073	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MECOMPHF_00074	1.36e-103	-	-	-	G	-	-	-	Major Facilitator Superfamily
MECOMPHF_00075	1.38e-176	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MECOMPHF_00076	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MECOMPHF_00077	4.1e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MECOMPHF_00078	1.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MECOMPHF_00079	2.92e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MECOMPHF_00080	1.01e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MECOMPHF_00081	4.51e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MECOMPHF_00082	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MECOMPHF_00083	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MECOMPHF_00084	8.32e-254	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MECOMPHF_00085	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MECOMPHF_00086	2.66e-310	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MECOMPHF_00087	9.87e-158	-	-	-	K	-	-	-	SIS domain
MECOMPHF_00088	3.73e-214	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00089	7.76e-84	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00090	4.36e-159	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00091	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MECOMPHF_00092	1.9e-224	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MECOMPHF_00093	4.27e-16	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MECOMPHF_00094	5.09e-91	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MECOMPHF_00095	6.08e-103	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MECOMPHF_00096	1.34e-278	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MECOMPHF_00097	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MECOMPHF_00098	1.62e-170	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00099	1.05e-76	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00100	1.13e-123	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MECOMPHF_00101	9.39e-134	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MECOMPHF_00104	1.15e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MECOMPHF_00105	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MECOMPHF_00106	2.55e-248	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MECOMPHF_00107	1.93e-43	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MECOMPHF_00108	2.93e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MECOMPHF_00109	2.08e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MECOMPHF_00110	9.88e-39	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MECOMPHF_00111	7.84e-58	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MECOMPHF_00112	9.31e-130	-	-	-	E	-	-	-	Amino acid permease
MECOMPHF_00113	1.87e-203	-	-	-	E	-	-	-	Amino acid permease
MECOMPHF_00114	6.99e-207	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MECOMPHF_00117	1.31e-148	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MECOMPHF_00118	1.91e-281	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MECOMPHF_00119	3.71e-154	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MECOMPHF_00120	2.72e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MECOMPHF_00121	2.77e-209	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MECOMPHF_00122	6.65e-80	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MECOMPHF_00123	2.42e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MECOMPHF_00125	1.57e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MECOMPHF_00126	6.38e-102	-	-	-	H	-	-	-	ThiF family
MECOMPHF_00128	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MECOMPHF_00129	8.65e-162	-	-	-	F	-	-	-	NUDIX domain
MECOMPHF_00130	1.71e-62	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MECOMPHF_00131	1.47e-104	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_00132	1.27e-36	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_00133	8.72e-174	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MECOMPHF_00134	3.4e-75	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MECOMPHF_00135	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MECOMPHF_00136	7.86e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
MECOMPHF_00137	9.05e-222	-	-	-	V	-	-	-	ABC transporter transmembrane region
MECOMPHF_00141	4.13e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MECOMPHF_00142	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MECOMPHF_00146	3.51e-309	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MECOMPHF_00147	1.7e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MECOMPHF_00148	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MECOMPHF_00149	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00150	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00151	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MECOMPHF_00152	4.43e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MECOMPHF_00153	2.26e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MECOMPHF_00154	2.69e-256	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MECOMPHF_00155	2.69e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MECOMPHF_00156	1.84e-237	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MECOMPHF_00157	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MECOMPHF_00158	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MECOMPHF_00159	1.91e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MECOMPHF_00160	1.62e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MECOMPHF_00161	3.68e-253	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MECOMPHF_00162	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MECOMPHF_00163	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MECOMPHF_00164	1.18e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MECOMPHF_00165	2.18e-269	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MECOMPHF_00166	2.64e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MECOMPHF_00167	1.32e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MECOMPHF_00168	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MECOMPHF_00169	1.37e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MECOMPHF_00170	9.96e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MECOMPHF_00171	2.23e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MECOMPHF_00172	1.06e-32	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MECOMPHF_00173	2.5e-202	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MECOMPHF_00174	3.8e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MECOMPHF_00175	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MECOMPHF_00176	1.54e-269	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MECOMPHF_00177	1.76e-109	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
MECOMPHF_00178	1.96e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MECOMPHF_00179	2.69e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MECOMPHF_00180	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MECOMPHF_00182	3.34e-197	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MECOMPHF_00183	3.2e-160	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MECOMPHF_00184	6.37e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MECOMPHF_00185	2e-277	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MECOMPHF_00186	5.65e-125	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MECOMPHF_00187	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MECOMPHF_00188	3.19e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
MECOMPHF_00189	5.95e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MECOMPHF_00190	3.86e-192	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MECOMPHF_00191	6.64e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MECOMPHF_00192	6.78e-246	-	-	-	L	-	-	-	Probable transposase
MECOMPHF_00193	1.19e-44	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MECOMPHF_00194	2.91e-08	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MECOMPHF_00195	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MECOMPHF_00196	1.04e-223	-	-	-	H	-	-	-	ThiF family
MECOMPHF_00197	8.09e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MECOMPHF_00198	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MECOMPHF_00199	3.46e-55	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MECOMPHF_00201	5.06e-197	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
MECOMPHF_00202	9.8e-265	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
MECOMPHF_00203	3.78e-169	-	-	-	-	-	-	-	-
MECOMPHF_00204	1.57e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MECOMPHF_00205	2.01e-141	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MECOMPHF_00206	4.62e-131	-	-	-	G	-	-	-	Aldose 1-epimerase
MECOMPHF_00207	1.01e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MECOMPHF_00208	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MECOMPHF_00209	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MECOMPHF_00210	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MECOMPHF_00211	2.19e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MECOMPHF_00212	2.3e-71	-	-	-	-	-	-	-	-
MECOMPHF_00214	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MECOMPHF_00215	2.51e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MECOMPHF_00216	1.03e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MECOMPHF_00217	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MECOMPHF_00218	6.32e-76	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MECOMPHF_00219	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MECOMPHF_00220	6.33e-148	-	-	-	-	-	-	-	-
MECOMPHF_00222	2.55e-148	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MECOMPHF_00223	2.86e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MECOMPHF_00224	1.09e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MECOMPHF_00225	9.59e-140	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MECOMPHF_00226	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MECOMPHF_00227	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MECOMPHF_00228	9.48e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MECOMPHF_00229	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MECOMPHF_00230	8.47e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MECOMPHF_00231	2.02e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MECOMPHF_00232	8.69e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MECOMPHF_00233	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MECOMPHF_00234	1.19e-117	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00235	6.86e-98	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00236	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MECOMPHF_00237	1.68e-51	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MECOMPHF_00238	3.1e-110	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MECOMPHF_00239	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MECOMPHF_00240	2.05e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MECOMPHF_00241	8.1e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
MECOMPHF_00242	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MECOMPHF_00243	1.85e-149	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MECOMPHF_00244	6.89e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MECOMPHF_00245	4.15e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MECOMPHF_00246	1.34e-151	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MECOMPHF_00247	8.07e-164	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MECOMPHF_00248	4.33e-103	-	-	-	-	-	-	-	-
MECOMPHF_00249	7.18e-182	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
MECOMPHF_00250	3.9e-79	-	-	-	-	-	-	-	-
MECOMPHF_00251	2.57e-20	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MECOMPHF_00253	1.06e-17	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MECOMPHF_00256	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MECOMPHF_00257	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MECOMPHF_00258	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MECOMPHF_00259	1.3e-104	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MECOMPHF_00262	1.45e-39	-	-	-	-	-	-	-	-
MECOMPHF_00264	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MECOMPHF_00265	8.27e-250	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MECOMPHF_00266	7.27e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MECOMPHF_00267	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MECOMPHF_00268	2.55e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MECOMPHF_00269	4.62e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MECOMPHF_00270	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MECOMPHF_00271	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
MECOMPHF_00272	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MECOMPHF_00273	4.45e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MECOMPHF_00274	2.81e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MECOMPHF_00275	3.54e-166	-	-	-	S	-	-	-	(CBS) domain
MECOMPHF_00276	9.33e-119	-	-	-	K	-	-	-	transcriptional regulator
MECOMPHF_00277	1.33e-275	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MECOMPHF_00278	7.73e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MECOMPHF_00279	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MECOMPHF_00280	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MECOMPHF_00281	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MECOMPHF_00282	8.01e-57	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MECOMPHF_00283	3.28e-130	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MECOMPHF_00284	5.69e-182	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MECOMPHF_00285	8.34e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MECOMPHF_00286	3.48e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MECOMPHF_00287	1.74e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MECOMPHF_00288	4.99e-74	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MECOMPHF_00289	1.11e-85	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MECOMPHF_00290	1.49e-32	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MECOMPHF_00291	4.44e-64	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MECOMPHF_00292	2.34e-57	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MECOMPHF_00293	4.36e-56	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MECOMPHF_00294	2.72e-101	-	-	-	-	-	-	-	-
MECOMPHF_00295	4.91e-62	-	-	-	-	-	-	-	-
MECOMPHF_00296	1.84e-63	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MECOMPHF_00297	7.22e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MECOMPHF_00298	1.07e-137	-	-	-	L	-	-	-	Resolvase, N terminal domain
MECOMPHF_00299	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MECOMPHF_00300	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MECOMPHF_00301	3.08e-43	-	-	-	-	-	-	-	-
MECOMPHF_00302	1.07e-204	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MECOMPHF_00303	4.71e-168	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MECOMPHF_00304	4.85e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MECOMPHF_00305	1.53e-145	-	-	-	-	-	-	-	-
MECOMPHF_00306	1.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MECOMPHF_00307	6.74e-285	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MECOMPHF_00308	5.22e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00309	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MECOMPHF_00310	3.41e-172	-	-	-	-	-	-	-	-
MECOMPHF_00311	4.46e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_00312	1.97e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MECOMPHF_00313	1.17e-85	-	-	-	-	-	-	-	-
MECOMPHF_00314	1.2e-148	-	-	-	GM	-	-	-	NmrA-like family
MECOMPHF_00315	2.62e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MECOMPHF_00316	5.32e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MECOMPHF_00317	4.22e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MECOMPHF_00318	5.07e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MECOMPHF_00319	1.97e-229	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MECOMPHF_00320	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MECOMPHF_00321	7.7e-110	-	-	-	-	-	-	-	-
MECOMPHF_00322	1.69e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MECOMPHF_00323	1.07e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MECOMPHF_00324	3.66e-161	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MECOMPHF_00325	1.67e-83	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MECOMPHF_00326	3.6e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MECOMPHF_00327	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00328	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00329	6.98e-206	-	-	-	L	-	-	-	HNH nucleases
MECOMPHF_00330	6.43e-159	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MECOMPHF_00332	1.38e-23	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MECOMPHF_00333	6.61e-83	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MECOMPHF_00334	2.82e-26	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MECOMPHF_00335	6.61e-261	-	-	-	L	-	-	-	Probable transposase
MECOMPHF_00336	3.71e-242	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MECOMPHF_00337	2.61e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MECOMPHF_00350	2.95e-143	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MECOMPHF_00351	5.87e-119	-	-	-	-	-	-	-	-
MECOMPHF_00352	3.14e-73	qacA	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_00357	7.28e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MECOMPHF_00358	3.71e-169	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
MECOMPHF_00359	6.12e-149	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MECOMPHF_00360	9.77e-48	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MECOMPHF_00361	1.29e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MECOMPHF_00362	2.27e-291	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MECOMPHF_00363	1.63e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MECOMPHF_00364	1.54e-141	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MECOMPHF_00365	9.96e-51	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MECOMPHF_00366	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MECOMPHF_00367	5.45e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MECOMPHF_00368	2.75e-72	-	-	-	-	-	-	-	-
MECOMPHF_00369	6.01e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MECOMPHF_00370	1.12e-146	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MECOMPHF_00371	3.23e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MECOMPHF_00372	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MECOMPHF_00373	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MECOMPHF_00374	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MECOMPHF_00375	7.94e-271	camS	-	-	S	-	-	-	sex pheromone
MECOMPHF_00376	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MECOMPHF_00377	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MECOMPHF_00378	1.19e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MECOMPHF_00380	7.75e-113	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MECOMPHF_00381	4.18e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MECOMPHF_00382	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MECOMPHF_00383	2.57e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MECOMPHF_00384	1.04e-202	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MECOMPHF_00385	3.35e-250	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MECOMPHF_00386	1.74e-68	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MECOMPHF_00387	7.5e-116	-	-	-	L	-	-	-	Probable transposase
MECOMPHF_00388	1.22e-49	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_00389	2.68e-52	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_00390	3.74e-34	-	-	-	-	-	-	-	-
MECOMPHF_00391	6.8e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MECOMPHF_00392	8.38e-37	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MECOMPHF_00393	2.11e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_00396	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MECOMPHF_00397	1.21e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MECOMPHF_00398	5.18e-234	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MECOMPHF_00399	1.25e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MECOMPHF_00400	6.48e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MECOMPHF_00401	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MECOMPHF_00402	1.18e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MECOMPHF_00403	2.16e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MECOMPHF_00404	2.63e-90	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MECOMPHF_00405	4.8e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MECOMPHF_00406	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MECOMPHF_00407	6.03e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MECOMPHF_00408	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MECOMPHF_00409	2.98e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MECOMPHF_00410	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MECOMPHF_00411	1.75e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MECOMPHF_00412	1.12e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MECOMPHF_00413	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MECOMPHF_00414	8.71e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MECOMPHF_00415	1.34e-103	uspA	-	-	T	-	-	-	universal stress protein
MECOMPHF_00416	9.14e-55	-	-	-	-	-	-	-	-
MECOMPHF_00417	6.82e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MECOMPHF_00418	1.83e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MECOMPHF_00419	1.52e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MECOMPHF_00420	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MECOMPHF_00421	5.46e-280	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MECOMPHF_00422	1.13e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MECOMPHF_00423	1.19e-17	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_00424	5.64e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
MECOMPHF_00425	2.5e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MECOMPHF_00426	6.37e-143	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MECOMPHF_00427	1.9e-190	-	-	-	-	-	-	-	-
MECOMPHF_00428	3.13e-35	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MECOMPHF_00429	4.14e-81	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MECOMPHF_00430	3.75e-98	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MECOMPHF_00431	2.87e-30	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MECOMPHF_00432	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MECOMPHF_00433	7e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MECOMPHF_00434	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MECOMPHF_00435	8.08e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MECOMPHF_00436	3.53e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MECOMPHF_00437	1.07e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MECOMPHF_00438	2.69e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MECOMPHF_00439	4.71e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MECOMPHF_00441	1.43e-71	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00442	5.11e-37	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00443	2.41e-144	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_00444	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MECOMPHF_00445	1.65e-291	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MECOMPHF_00446	1.8e-51	-	-	-	O	-	-	-	Matrixin
MECOMPHF_00447	2e-42	-	-	-	-	-	-	-	-
MECOMPHF_00448	7.59e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
MECOMPHF_00449	5.51e-78	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MECOMPHF_00450	2.27e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MECOMPHF_00451	4.37e-206	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00452	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00453	9.35e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MECOMPHF_00454	4.13e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MECOMPHF_00455	5.7e-44	-	-	-	-	-	-	-	-
MECOMPHF_00456	2.05e-68	-	-	-	-	-	-	-	-
MECOMPHF_00457	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00459	1.38e-121	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00460	6.53e-62	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00461	1.22e-18	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00462	2.44e-25	-	-	-	-	-	-	-	-
MECOMPHF_00463	1.27e-262	-	-	-	G	-	-	-	Major Facilitator Superfamily
MECOMPHF_00464	2.36e-52	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MECOMPHF_00465	1.71e-61	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_00469	8.09e-235	-	-	-	S	-	-	-	AAA domain
MECOMPHF_00470	2.41e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MECOMPHF_00471	1.16e-31	-	-	-	-	-	-	-	-
MECOMPHF_00472	7.22e-207	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MECOMPHF_00473	8.07e-163	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MECOMPHF_00474	7.06e-170	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MECOMPHF_00475	2.01e-18	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MECOMPHF_00476	2.2e-79	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MECOMPHF_00477	1.22e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MECOMPHF_00478	5.31e-90	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MECOMPHF_00479	1.01e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MECOMPHF_00480	3.77e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MECOMPHF_00481	3.86e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MECOMPHF_00482	3.84e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MECOMPHF_00483	1.58e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MECOMPHF_00484	1.19e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MECOMPHF_00485	3.16e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MECOMPHF_00486	4.41e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MECOMPHF_00487	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MECOMPHF_00488	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MECOMPHF_00489	3.15e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MECOMPHF_00490	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MECOMPHF_00491	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MECOMPHF_00492	5.1e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MECOMPHF_00493	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MECOMPHF_00494	9.04e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MECOMPHF_00495	7.53e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MECOMPHF_00496	1.28e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MECOMPHF_00497	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MECOMPHF_00498	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MECOMPHF_00499	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MECOMPHF_00500	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MECOMPHF_00501	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MECOMPHF_00502	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MECOMPHF_00503	6.37e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MECOMPHF_00504	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MECOMPHF_00505	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MECOMPHF_00506	7.45e-158	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MECOMPHF_00507	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MECOMPHF_00508	4.33e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MECOMPHF_00509	5.7e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MECOMPHF_00510	4.67e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MECOMPHF_00511	3.85e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MECOMPHF_00512	3.29e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MECOMPHF_00513	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MECOMPHF_00514	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MECOMPHF_00515	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MECOMPHF_00516	1.21e-90	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MECOMPHF_00517	2.06e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MECOMPHF_00518	1.11e-239	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MECOMPHF_00519	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MECOMPHF_00520	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MECOMPHF_00521	1.91e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MECOMPHF_00522	4.35e-125	-	-	-	-	-	-	-	-
MECOMPHF_00523	6.18e-205	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MECOMPHF_00524	2.33e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MECOMPHF_00525	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MECOMPHF_00526	1.87e-118	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MECOMPHF_00527	7.47e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MECOMPHF_00528	8.49e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MECOMPHF_00529	4.51e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MECOMPHF_00530	6.45e-175	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00531	1.86e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00532	6.98e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00533	5.03e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MECOMPHF_00534	5.29e-218	ybbR	-	-	S	-	-	-	YbbR-like protein
MECOMPHF_00535	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MECOMPHF_00536	1.76e-193	-	-	-	S	-	-	-	hydrolase
MECOMPHF_00537	6.89e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MECOMPHF_00538	1.86e-153	-	-	-	-	-	-	-	-
MECOMPHF_00539	8.4e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MECOMPHF_00540	4.12e-274	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MECOMPHF_00541	2.67e-72	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MECOMPHF_00542	7.38e-81	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MECOMPHF_00543	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_00544	8.68e-28	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_00545	1.85e-160	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_00546	3.98e-148	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_00547	1.03e-236	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MECOMPHF_00548	1.18e-19	-	-	-	E	-	-	-	Amino acid permease
MECOMPHF_00549	0.0	-	-	-	E	-	-	-	Amino acid permease
MECOMPHF_00550	1.21e-50	-	-	-	-	-	-	-	-
MECOMPHF_00552	4.46e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MECOMPHF_00553	1.9e-65	-	-	-	-	-	-	-	-
MECOMPHF_00554	3.4e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MECOMPHF_00555	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MECOMPHF_00556	7.06e-30	-	-	-	-	-	-	-	-
MECOMPHF_00557	6.33e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MECOMPHF_00558	1.01e-226	lipA	-	-	I	-	-	-	Carboxylesterase family
MECOMPHF_00560	2.49e-277	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_00561	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MECOMPHF_00562	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MECOMPHF_00563	2.83e-167	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MECOMPHF_00564	1.97e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MECOMPHF_00565	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MECOMPHF_00566	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MECOMPHF_00567	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MECOMPHF_00568	2.83e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MECOMPHF_00569	1.04e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MECOMPHF_00570	6.6e-91	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MECOMPHF_00571	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MECOMPHF_00572	1.34e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MECOMPHF_00573	5.59e-251	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MECOMPHF_00574	7.59e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MECOMPHF_00575	6.71e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MECOMPHF_00576	8.78e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MECOMPHF_00577	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MECOMPHF_00578	3.93e-28	-	-	-	S	-	-	-	ASCH
MECOMPHF_00579	6.84e-57	-	-	-	S	-	-	-	ASCH
MECOMPHF_00580	7.26e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MECOMPHF_00581	4.78e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MECOMPHF_00582	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MECOMPHF_00583	1.87e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MECOMPHF_00584	4.49e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MECOMPHF_00585	8.11e-190	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MECOMPHF_00586	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MECOMPHF_00587	2.26e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MECOMPHF_00588	2.51e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MECOMPHF_00589	8.07e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MECOMPHF_00590	4.3e-68	-	-	-	-	-	-	-	-
MECOMPHF_00591	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MECOMPHF_00592	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MECOMPHF_00593	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MECOMPHF_00594	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MECOMPHF_00595	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MECOMPHF_00596	5.34e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MECOMPHF_00597	6.3e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MECOMPHF_00598	3.56e-233	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MECOMPHF_00599	7.39e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00600	3.53e-203	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MECOMPHF_00601	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00602	4.99e-29	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00603	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00604	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MECOMPHF_00605	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MECOMPHF_00606	4.9e-234	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MECOMPHF_00607	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_00608	7.95e-59	-	-	-	-	-	-	-	-
MECOMPHF_00609	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MECOMPHF_00610	2.6e-175	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MECOMPHF_00611	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MECOMPHF_00612	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MECOMPHF_00613	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MECOMPHF_00614	4.2e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MECOMPHF_00615	2.41e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MECOMPHF_00616	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MECOMPHF_00617	2.11e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MECOMPHF_00618	4.12e-47	-	-	-	-	-	-	-	-
MECOMPHF_00619	2.87e-101	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MECOMPHF_00620	2.08e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
MECOMPHF_00621	2.33e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
MECOMPHF_00622	2.57e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
MECOMPHF_00623	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MECOMPHF_00624	1.33e-45	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MECOMPHF_00625	4.46e-93	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MECOMPHF_00626	9.63e-84	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MECOMPHF_00627	5.32e-26	-	-	-	-	-	-	-	-
MECOMPHF_00628	1.36e-268	-	-	-	-	-	-	-	-
MECOMPHF_00629	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MECOMPHF_00630	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MECOMPHF_00631	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MECOMPHF_00632	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MECOMPHF_00633	2.65e-189	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MECOMPHF_00634	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MECOMPHF_00635	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MECOMPHF_00636	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MECOMPHF_00637	4.3e-256	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MECOMPHF_00638	2.87e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MECOMPHF_00639	1.79e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MECOMPHF_00640	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MECOMPHF_00641	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MECOMPHF_00642	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MECOMPHF_00643	2.06e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MECOMPHF_00644	5.05e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MECOMPHF_00645	1e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MECOMPHF_00646	4.45e-83	-	-	-	-	-	-	-	-
MECOMPHF_00647	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MECOMPHF_00648	1.51e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MECOMPHF_00649	1.31e-86	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
MECOMPHF_00651	6.41e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MECOMPHF_00652	1.1e-73	-	-	-	-	-	-	-	-
MECOMPHF_00653	1.19e-169	-	-	-	-	-	-	-	-
MECOMPHF_00654	3.12e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MECOMPHF_00655	2.91e-33	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MECOMPHF_00656	1.57e-123	-	-	-	-	-	-	-	-
MECOMPHF_00657	1.41e-148	-	-	-	S	-	-	-	Fic/DOC family
MECOMPHF_00658	6.71e-90	-	-	-	-	-	-	-	-
MECOMPHF_00659	3.22e-116	-	-	-	-	-	-	-	-
MECOMPHF_00660	4.01e-80	-	-	-	-	-	-	-	-
MECOMPHF_00661	3.36e-46	-	-	-	-	-	-	-	-
MECOMPHF_00662	0.0	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MECOMPHF_00663	1.55e-206	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MECOMPHF_00664	4.38e-60	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MECOMPHF_00665	1.01e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MECOMPHF_00666	8.01e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MECOMPHF_00667	4.33e-195	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MECOMPHF_00668	1.3e-265	-	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_00669	1.46e-145	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MECOMPHF_00670	3.85e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
MECOMPHF_00671	2.35e-106	-	-	-	C	-	-	-	Flavodoxin
MECOMPHF_00672	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MECOMPHF_00673	6.54e-37	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MECOMPHF_00674	1.27e-313	ynbB	-	-	P	-	-	-	aluminum resistance
MECOMPHF_00675	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MECOMPHF_00676	9.79e-86	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MECOMPHF_00677	2.79e-61	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MECOMPHF_00678	1.06e-21	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MECOMPHF_00679	9.45e-82	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MECOMPHF_00680	1.49e-122	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_00681	6.39e-120	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_00682	8.81e-108	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_00683	3.88e-49	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MECOMPHF_00684	2.33e-188	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MECOMPHF_00685	2.93e-32	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MECOMPHF_00686	3.73e-239	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MECOMPHF_00687	1.04e-180	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MECOMPHF_00688	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MECOMPHF_00689	7.91e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MECOMPHF_00690	3.61e-81	-	-	-	K	-	-	-	Transcriptional regulator
MECOMPHF_00691	1.56e-86	-	-	-	K	-	-	-	Transcriptional regulator
MECOMPHF_00692	6.26e-14	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MECOMPHF_00693	4.8e-80	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MECOMPHF_00694	6.56e-308	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MECOMPHF_00695	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MECOMPHF_00696	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MECOMPHF_00697	7.04e-63	-	-	-	-	-	-	-	-
MECOMPHF_00698	4.57e-49	-	-	-	E	-	-	-	amino acid
MECOMPHF_00699	3.67e-74	-	-	-	E	-	-	-	amino acid
MECOMPHF_00700	3.17e-94	-	-	-	-	-	-	-	-
MECOMPHF_00701	3.2e-125	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MECOMPHF_00702	2.73e-156	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MECOMPHF_00703	3.29e-82	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MECOMPHF_00704	2.05e-42	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MECOMPHF_00705	5.59e-76	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MECOMPHF_00706	7.56e-48	-	-	-	-	-	-	-	-
MECOMPHF_00707	7.52e-95	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MECOMPHF_00708	1.37e-116	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MECOMPHF_00709	6.1e-191	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MECOMPHF_00710	1.85e-35	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MECOMPHF_00711	8.83e-204	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MECOMPHF_00712	9.23e-219	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MECOMPHF_00713	2.53e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MECOMPHF_00714	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_00715	1.15e-257	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MECOMPHF_00716	1.4e-203	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MECOMPHF_00717	3.25e-186	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MECOMPHF_00718	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MECOMPHF_00719	1.74e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MECOMPHF_00720	2.87e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MECOMPHF_00721	6.51e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MECOMPHF_00722	2.86e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_00723	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MECOMPHF_00724	7.68e-204	-	-	-	-	-	-	-	-
MECOMPHF_00725	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MECOMPHF_00726	1.16e-162	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MECOMPHF_00727	5.96e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MECOMPHF_00728	4.91e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MECOMPHF_00729	1.38e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MECOMPHF_00730	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MECOMPHF_00731	4.87e-183	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MECOMPHF_00732	1.08e-52	-	-	-	L	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR associated protein Cas6
MECOMPHF_00733	1.67e-127	-	-	-	S	ko:K19088	-	ko00000,ko02048	CRISPR-associated protein (Cas_CXXC_CXXC)
MECOMPHF_00734	1.12e-131	-	-	-	L	ko:K19075	-	ko00000,ko02048	CRISPR-associated negative auto-regulator DevR/Csa2
MECOMPHF_00735	7e-83	-	-	-	L	ko:K19090	-	ko00000,ko02048	CRISPR-associated protein Cas5
MECOMPHF_00736	1.67e-218	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MECOMPHF_00737	1.46e-63	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
MECOMPHF_00738	1.79e-155	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MECOMPHF_00739	9.43e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MECOMPHF_00740	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MECOMPHF_00741	6.45e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MECOMPHF_00742	1.52e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MECOMPHF_00743	5.46e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MECOMPHF_00744	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MECOMPHF_00745	1.08e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MECOMPHF_00746	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MECOMPHF_00747	8.11e-121	-	-	-	-	-	-	-	-
MECOMPHF_00748	5.27e-123	-	-	-	-	-	-	-	-
MECOMPHF_00749	1.1e-120	-	-	-	-	-	-	-	-
MECOMPHF_00751	0.0	-	-	-	S	-	-	-	PglZ domain
MECOMPHF_00752	6.54e-61	-	-	-	LO	-	-	-	Psort location Cytoplasmic, score 8.87
MECOMPHF_00753	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
MECOMPHF_00754	1.62e-250	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MECOMPHF_00755	8.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
MECOMPHF_00756	1.92e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
MECOMPHF_00757	1.38e-293	-	-	-	S	-	-	-	Protein of unknown function DUF262
MECOMPHF_00758	4.93e-70	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MECOMPHF_00759	3.48e-86	-	-	-	S	-	-	-	ASCH domain
MECOMPHF_00760	4.27e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MECOMPHF_00761	7.07e-106	-	-	-	-	-	-	-	-
MECOMPHF_00762	0.0	-	-	-	-	-	-	-	-
MECOMPHF_00763	2.14e-44	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_00764	1.66e-73	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MECOMPHF_00765	1.79e-214	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MECOMPHF_00766	2.74e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MECOMPHF_00767	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MECOMPHF_00768	7.75e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MECOMPHF_00769	2.06e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MECOMPHF_00770	2.58e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MECOMPHF_00771	1.13e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MECOMPHF_00772	9.58e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MECOMPHF_00773	5.59e-109	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MECOMPHF_00774	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MECOMPHF_00775	2.12e-164	csrR	-	-	K	-	-	-	response regulator
MECOMPHF_00776	2.03e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MECOMPHF_00777	3.81e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MECOMPHF_00778	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MECOMPHF_00779	2.26e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MECOMPHF_00780	5.48e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MECOMPHF_00781	4.97e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MECOMPHF_00782	2.51e-120	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MECOMPHF_00783	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MECOMPHF_00784	4.77e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MECOMPHF_00785	1.44e-74	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MECOMPHF_00786	4.66e-289	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MECOMPHF_00787	2.61e-36	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MECOMPHF_00788	1.85e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MECOMPHF_00789	2.18e-85	-	-	-	-	-	-	-	-
MECOMPHF_00790	1.07e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MECOMPHF_00791	5.68e-67	-	-	-	S	-	-	-	Peptidase family M23
MECOMPHF_00792	2.32e-197	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MECOMPHF_00793	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MECOMPHF_00794	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MECOMPHF_00795	2.03e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MECOMPHF_00796	1.25e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MECOMPHF_00797	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MECOMPHF_00798	2.68e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MECOMPHF_00799	2.22e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MECOMPHF_00800	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MECOMPHF_00801	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MECOMPHF_00802	8.62e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MECOMPHF_00803	2.42e-160	-	-	-	S	-	-	-	Peptidase family M23
MECOMPHF_00804	2.69e-40	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MECOMPHF_00805	1.82e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MECOMPHF_00806	6.68e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MECOMPHF_00807	8.53e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MECOMPHF_00808	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MECOMPHF_00809	6.31e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MECOMPHF_00810	1.57e-176	-	-	-	-	-	-	-	-
MECOMPHF_00811	4.92e-183	-	-	-	-	-	-	-	-
MECOMPHF_00812	9.96e-46	-	-	-	-	-	-	-	-
MECOMPHF_00813	2.84e-44	-	-	-	-	-	-	-	-
MECOMPHF_00814	5.48e-118	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MECOMPHF_00815	3.38e-274	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MECOMPHF_00816	7.18e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MECOMPHF_00817	2.49e-190	yycI	-	-	S	-	-	-	YycH protein
MECOMPHF_00818	2.31e-313	yycH	-	-	S	-	-	-	YycH protein
MECOMPHF_00819	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MECOMPHF_00820	2.8e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MECOMPHF_00822	3.67e-45	-	-	-	-	-	-	-	-
MECOMPHF_00825	1.16e-211	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00826	3.02e-172	-	-	-	-	-	-	-	-
MECOMPHF_00827	8.98e-203	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00828	2.05e-34	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_00829	1.25e-188	-	-	-	I	-	-	-	Acyl-transferase
MECOMPHF_00830	7.13e-87	-	-	-	-	-	-	-	-
MECOMPHF_00831	8.43e-19	-	-	-	-	-	-	-	-
MECOMPHF_00832	2.05e-112	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_00833	1.46e-53	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_00834	4.36e-202	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MECOMPHF_00835	6.18e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
MECOMPHF_00836	1.29e-13	-	-	-	M	-	-	-	Glycosyl transferase family 8
MECOMPHF_00837	4.31e-189	-	-	-	M	-	-	-	Glycosyl transferase family 8
MECOMPHF_00838	1.31e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MECOMPHF_00839	2.92e-46	-	-	-	S	-	-	-	Cytochrome b5
MECOMPHF_00840	4.64e-143	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MECOMPHF_00841	1.01e-09	-	-	-	K	-	-	-	LysR substrate binding domain
MECOMPHF_00842	3.06e-80	-	-	-	K	-	-	-	LysR substrate binding domain
MECOMPHF_00843	1.05e-48	-	-	-	K	-	-	-	LysR substrate binding domain
MECOMPHF_00844	2.52e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MECOMPHF_00845	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00846	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_00847	5.69e-195	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_00848	5.64e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00849	6.25e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MECOMPHF_00850	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MECOMPHF_00851	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00852	1.07e-104	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MECOMPHF_00853	7.14e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MECOMPHF_00854	7.51e-166	-	-	-	F	-	-	-	glutamine amidotransferase
MECOMPHF_00855	5.29e-160	-	-	-	-	-	-	-	-
MECOMPHF_00856	1.03e-09	-	-	-	-	-	-	-	-
MECOMPHF_00857	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MECOMPHF_00858	1.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MECOMPHF_00859	1.53e-268	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MECOMPHF_00860	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_00861	1.62e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MECOMPHF_00862	2.27e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MECOMPHF_00863	4.12e-49	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MECOMPHF_00864	1.07e-53	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MECOMPHF_00866	1.47e-32	-	-	-	L	-	-	-	Transposase
MECOMPHF_00867	1.02e-116	-	-	-	L	-	-	-	Transposase
MECOMPHF_00868	3.44e-287	ycaM	-	-	E	-	-	-	amino acid
MECOMPHF_00869	5.27e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MECOMPHF_00870	0.0	-	-	-	S	-	-	-	SH3-like domain
MECOMPHF_00871	4.72e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MECOMPHF_00872	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MECOMPHF_00873	1.09e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MECOMPHF_00874	2.97e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MECOMPHF_00875	4.38e-108	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MECOMPHF_00876	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MECOMPHF_00877	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MECOMPHF_00878	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MECOMPHF_00879	7.7e-80	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MECOMPHF_00880	1.41e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MECOMPHF_00881	1.11e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MECOMPHF_00882	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MECOMPHF_00883	5.88e-44	-	-	-	-	-	-	-	-
MECOMPHF_00884	3.57e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MECOMPHF_00885	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MECOMPHF_00886	5.41e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MECOMPHF_00887	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MECOMPHF_00888	9.01e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MECOMPHF_00889	2.4e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MECOMPHF_00890	2.26e-267	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MECOMPHF_00891	1.01e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MECOMPHF_00892	2.66e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MECOMPHF_00893	6.05e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MECOMPHF_00894	3.54e-187	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MECOMPHF_00895	2.8e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MECOMPHF_00896	2.62e-301	ymfH	-	-	S	-	-	-	Peptidase M16
MECOMPHF_00897	8.89e-290	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MECOMPHF_00898	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MECOMPHF_00899	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MECOMPHF_00900	1.49e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MECOMPHF_00901	8.55e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MECOMPHF_00902	1.12e-30	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MECOMPHF_00903	4.91e-37	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MECOMPHF_00904	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MECOMPHF_00905	7.43e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MECOMPHF_00906	2.1e-151	-	-	-	S	-	-	-	SNARE associated Golgi protein
MECOMPHF_00907	3.24e-41	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MECOMPHF_00908	6.33e-316	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MECOMPHF_00909	8.64e-40	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MECOMPHF_00910	4.97e-218	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MECOMPHF_00911	1.25e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MECOMPHF_00912	4.88e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MECOMPHF_00913	7.26e-146	-	-	-	S	-	-	-	CYTH
MECOMPHF_00914	3.88e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
MECOMPHF_00915	7.91e-206	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MECOMPHF_00916	4.31e-177	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MECOMPHF_00917	1.54e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MECOMPHF_00918	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MECOMPHF_00919	1.83e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MECOMPHF_00920	5.25e-37	-	-	-	-	-	-	-	-
MECOMPHF_00921	2.23e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MECOMPHF_00922	1.65e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MECOMPHF_00923	9.02e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MECOMPHF_00924	1.5e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MECOMPHF_00925	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MECOMPHF_00926	6.81e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MECOMPHF_00927	1.88e-34	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MECOMPHF_00928	1.67e-71	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MECOMPHF_00929	3.18e-31	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MECOMPHF_00930	2.26e-65	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MECOMPHF_00931	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MECOMPHF_00932	6.55e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MECOMPHF_00933	4.28e-111	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MECOMPHF_00934	1.64e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MECOMPHF_00935	1.08e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MECOMPHF_00936	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MECOMPHF_00937	6.03e-57	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MECOMPHF_00938	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MECOMPHF_00939	3.33e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MECOMPHF_00940	8.42e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MECOMPHF_00941	1.52e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MECOMPHF_00942	4.16e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MECOMPHF_00943	1.99e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MECOMPHF_00944	2.32e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MECOMPHF_00945	5.69e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MECOMPHF_00946	2.14e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MECOMPHF_00947	2.8e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MECOMPHF_00948	1.26e-121	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MECOMPHF_00949	2.12e-254	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MECOMPHF_00950	1.47e-06	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MECOMPHF_00952	2.41e-37	-	-	-	-	-	-	-	-
MECOMPHF_00953	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MECOMPHF_00954	3.7e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_00955	1.75e-276	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MECOMPHF_00956	1.22e-218	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MECOMPHF_00957	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MECOMPHF_00958	3.58e-155	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MECOMPHF_00959	4.37e-165	-	-	-	-	-	-	-	-
MECOMPHF_00960	1.95e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MECOMPHF_00961	2.5e-312	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MECOMPHF_00962	2.2e-118	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MECOMPHF_00963	9.17e-29	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MECOMPHF_00964	5.78e-305	-	-	-	E	-	-	-	amino acid
MECOMPHF_00965	3.11e-38	-	-	-	-	-	-	-	-
MECOMPHF_00966	2.52e-154	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MECOMPHF_00967	4.65e-168	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
MECOMPHF_00968	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MECOMPHF_00969	3.09e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MECOMPHF_00970	2.27e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MECOMPHF_00971	3.37e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MECOMPHF_00972	2.53e-198	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MECOMPHF_00973	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MECOMPHF_00974	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MECOMPHF_00975	2.46e-85	-	-	-	-	-	-	-	-
MECOMPHF_00976	1.7e-51	-	-	-	-	-	-	-	-
MECOMPHF_00977	2.21e-84	-	-	-	M	-	-	-	Rib/alpha-like repeat
MECOMPHF_00978	9.94e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MECOMPHF_00980	2.93e-25	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_00982	1.32e-54	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_00983	3.43e-203	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MECOMPHF_00984	3.37e-82	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MECOMPHF_00985	1.24e-79	-	-	-	L	-	-	-	Resolvase, N terminal domain
MECOMPHF_00986	4.53e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MECOMPHF_00987	4.73e-120	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MECOMPHF_00988	1.01e-102	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MECOMPHF_00989	5.77e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MECOMPHF_00990	1.02e-103	-	-	-	K	-	-	-	Transcriptional regulator
MECOMPHF_00991	3.15e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MECOMPHF_00992	6.25e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MECOMPHF_00993	8.57e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MECOMPHF_00994	1.09e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MECOMPHF_00995	2.2e-293	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MECOMPHF_00996	5.23e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MECOMPHF_00997	6.93e-96	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MECOMPHF_00998	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MECOMPHF_00999	1.78e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MECOMPHF_01000	2.6e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MECOMPHF_01001	2.68e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MECOMPHF_01002	1.3e-240	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MECOMPHF_01003	4.63e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MECOMPHF_01004	0.0	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01005	2.61e-12	-	-	-	-	-	-	-	-
MECOMPHF_01006	3.19e-43	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MECOMPHF_01007	5.35e-69	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MECOMPHF_01008	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MECOMPHF_01009	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MECOMPHF_01010	1.12e-296	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MECOMPHF_01011	5.33e-119	-	-	-	-	-	-	-	-
MECOMPHF_01012	4.77e-48	-	-	-	-	-	-	-	-
MECOMPHF_01014	4.56e-135	-	-	-	-	-	-	-	-
MECOMPHF_01015	7.64e-161	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
MECOMPHF_01016	2.64e-94	-	-	-	O	-	-	-	OsmC-like protein
MECOMPHF_01017	9.57e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MECOMPHF_01018	5.97e-149	sptS	-	-	T	-	-	-	Histidine kinase
MECOMPHF_01019	1.22e-36	sptS	-	-	T	-	-	-	Histidine kinase
MECOMPHF_01020	4.29e-47	dltr	-	-	K	-	-	-	response regulator
MECOMPHF_01021	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
MECOMPHF_01022	9.26e-175	-	-	-	EG	-	-	-	EamA-like transporter family
MECOMPHF_01023	1.44e-141	-	-	-	-	-	-	-	-
MECOMPHF_01024	1.35e-102	-	-	-	-	-	-	-	-
MECOMPHF_01025	8.64e-225	-	-	-	S	-	-	-	DUF218 domain
MECOMPHF_01026	1.58e-88	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MECOMPHF_01027	2.07e-93	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MECOMPHF_01028	1.18e-113	-	-	-	-	-	-	-	-
MECOMPHF_01029	7.09e-76	-	-	-	-	-	-	-	-
MECOMPHF_01030	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MECOMPHF_01031	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MECOMPHF_01032	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MECOMPHF_01035	9.06e-259	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MECOMPHF_01036	3.5e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MECOMPHF_01037	6.01e-247	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MECOMPHF_01038	1.64e-237	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MECOMPHF_01039	8.74e-195	-	-	-	C	-	-	-	Nitroreductase
MECOMPHF_01041	1.24e-196	-	-	-	-	-	-	-	-
MECOMPHF_01042	3.02e-67	-	-	-	-	-	-	-	-
MECOMPHF_01043	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MECOMPHF_01044	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MECOMPHF_01045	7.82e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MECOMPHF_01046	2.66e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MECOMPHF_01047	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01048	4.8e-72	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
MECOMPHF_01049	1.33e-46	-	-	-	S	-	-	-	Plasmid maintenance system killer
MECOMPHF_01050	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MECOMPHF_01051	6.03e-57	-	-	-	-	-	-	-	-
MECOMPHF_01052	1.27e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MECOMPHF_01053	1.83e-101	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MECOMPHF_01054	2.85e-242	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MECOMPHF_01055	0.0	yhaN	-	-	L	-	-	-	AAA domain
MECOMPHF_01056	1.01e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MECOMPHF_01057	2.07e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MECOMPHF_01058	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MECOMPHF_01059	7.28e-209	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MECOMPHF_01060	3e-28	-	-	-	K	-	-	-	rpiR family
MECOMPHF_01061	1.9e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MECOMPHF_01062	7.57e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
MECOMPHF_01063	4.93e-123	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MECOMPHF_01064	1.24e-21	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01065	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01066	4e-16	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01067	8.9e-249	-	-	-	S	-	-	-	DUF218 domain
MECOMPHF_01068	2.61e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MECOMPHF_01069	1.83e-63	-	-	-	-	-	-	-	-
MECOMPHF_01070	3.33e-202	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MECOMPHF_01071	3.77e-114	-	-	-	S	-	-	-	Putative adhesin
MECOMPHF_01072	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MECOMPHF_01073	3.93e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MECOMPHF_01074	1.82e-65	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MECOMPHF_01075	3.69e-259	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MECOMPHF_01076	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MECOMPHF_01077	6.45e-301	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MECOMPHF_01078	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MECOMPHF_01079	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MECOMPHF_01080	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MECOMPHF_01081	1.55e-173	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
MECOMPHF_01083	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MECOMPHF_01084	1.53e-38	-	-	-	-	-	-	-	-
MECOMPHF_01085	2.42e-49	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_01086	3.73e-76	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_01087	1.42e-107	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MECOMPHF_01088	2.01e-179	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MECOMPHF_01089	7.39e-314	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
MECOMPHF_01090	2.02e-108	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01091	1.55e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MECOMPHF_01092	2.48e-69	-	-	-	GK	-	-	-	ROK family
MECOMPHF_01093	4.7e-87	-	-	-	GK	-	-	-	ROK family
MECOMPHF_01094	1.12e-54	-	-	-	-	-	-	-	-
MECOMPHF_01095	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MECOMPHF_01096	2.02e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MECOMPHF_01097	1.25e-114	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MECOMPHF_01098	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MECOMPHF_01099	1.28e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MECOMPHF_01100	9.13e-43	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MECOMPHF_01101	2.55e-64	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MECOMPHF_01102	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_01103	3.33e-204	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MECOMPHF_01104	9.26e-289	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MECOMPHF_01105	3.5e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MECOMPHF_01106	3.01e-136	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
MECOMPHF_01107	3.74e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MECOMPHF_01108	2.47e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MECOMPHF_01109	1.55e-79	-	-	-	-	-	-	-	-
MECOMPHF_01110	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MECOMPHF_01111	7.07e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MECOMPHF_01112	3.01e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MECOMPHF_01113	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MECOMPHF_01114	1.65e-285	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MECOMPHF_01115	8.71e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MECOMPHF_01116	9.85e-199	-	-	-	S	-	-	-	reductase
MECOMPHF_01117	6.4e-110	yxeH	-	-	S	-	-	-	hydrolase
MECOMPHF_01118	2.07e-58	yxeH	-	-	S	-	-	-	hydrolase
MECOMPHF_01119	2.84e-21	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01120	5.1e-57	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01121	5.75e-32	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01122	5.5e-54	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01123	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MECOMPHF_01124	1.73e-40	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MECOMPHF_01125	2.26e-70	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MECOMPHF_01126	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MECOMPHF_01127	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MECOMPHF_01128	2.3e-306	oatA	-	-	I	-	-	-	Acyltransferase
MECOMPHF_01129	2.76e-101	oatA	-	-	I	-	-	-	Acyltransferase
MECOMPHF_01130	1.05e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MECOMPHF_01131	9.72e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MECOMPHF_01132	6.62e-48	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MECOMPHF_01133	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MECOMPHF_01134	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MECOMPHF_01135	9.47e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MECOMPHF_01136	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MECOMPHF_01137	9.45e-234	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MECOMPHF_01138	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MECOMPHF_01139	4.41e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MECOMPHF_01140	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MECOMPHF_01141	1.62e-80	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MECOMPHF_01142	2.03e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MECOMPHF_01143	1.16e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MECOMPHF_01144	1.1e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MECOMPHF_01145	1.79e-147	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MECOMPHF_01146	5.14e-58	-	-	-	M	-	-	-	Lysin motif
MECOMPHF_01147	1.81e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MECOMPHF_01148	1.81e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MECOMPHF_01149	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MECOMPHF_01150	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MECOMPHF_01151	3.15e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MECOMPHF_01152	3.57e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MECOMPHF_01153	1.26e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MECOMPHF_01154	9.98e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MECOMPHF_01155	2.03e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MECOMPHF_01156	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MECOMPHF_01157	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MECOMPHF_01158	6.7e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MECOMPHF_01159	3e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MECOMPHF_01161	2.73e-78	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_01162	1.83e-176	-	-	-	S	-	-	-	YSIRK type signal peptide
MECOMPHF_01163	4.72e-16	-	-	-	M	-	-	-	domain protein
MECOMPHF_01165	4.04e-70	-	-	-	M	-	-	-	domain protein
MECOMPHF_01167	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MECOMPHF_01168	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MECOMPHF_01169	4.08e-47	-	-	-	-	-	-	-	-
MECOMPHF_01170	6.02e-83	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MECOMPHF_01171	1.22e-133	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MECOMPHF_01172	4.88e-131	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MECOMPHF_01173	2.52e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MECOMPHF_01174	5.32e-207	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MECOMPHF_01175	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MECOMPHF_01176	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MECOMPHF_01177	9.37e-169	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MECOMPHF_01178	3.87e-80	-	-	-	S	-	-	-	SdpI/YhfL protein family
MECOMPHF_01179	5.35e-220	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MECOMPHF_01180	6.69e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MECOMPHF_01181	2.87e-47	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MECOMPHF_01182	2.64e-50	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MECOMPHF_01184	2.34e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MECOMPHF_01185	2.53e-240	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MECOMPHF_01186	2.17e-108	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MECOMPHF_01187	1.18e-55	-	-	-	-	-	-	-	-
MECOMPHF_01188	5.84e-95	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MECOMPHF_01189	6.15e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MECOMPHF_01190	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MECOMPHF_01191	8.35e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MECOMPHF_01192	3.81e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MECOMPHF_01193	5.73e-120	-	-	-	S	-	-	-	VanZ like family
MECOMPHF_01194	5.04e-71	-	-	-	-	-	-	-	-
MECOMPHF_01195	7.71e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MECOMPHF_01196	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MECOMPHF_01197	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MECOMPHF_01198	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MECOMPHF_01199	1.21e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MECOMPHF_01200	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MECOMPHF_01201	8.62e-120	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MECOMPHF_01202	2.41e-45	-	-	-	-	-	-	-	-
MECOMPHF_01203	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MECOMPHF_01204	2.26e-108	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MECOMPHF_01205	1.44e-138	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MECOMPHF_01206	2.32e-124	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MECOMPHF_01207	8.53e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MECOMPHF_01208	5.2e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MECOMPHF_01209	7.71e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MECOMPHF_01210	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MECOMPHF_01211	1.37e-306	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MECOMPHF_01212	2.72e-190	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MECOMPHF_01213	2.2e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
MECOMPHF_01214	9.05e-114	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
MECOMPHF_01215	6.85e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MECOMPHF_01216	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
MECOMPHF_01217	2.96e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
MECOMPHF_01218	4.78e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MECOMPHF_01219	4.09e-23	-	-	-	-	-	-	-	-
MECOMPHF_01220	5.9e-69	-	-	-	-	-	-	-	-
MECOMPHF_01221	2.58e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01222	1.94e-167	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MECOMPHF_01223	5.19e-227	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MECOMPHF_01224	8.76e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MECOMPHF_01225	3.01e-42	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01226	2.1e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
MECOMPHF_01227	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MECOMPHF_01228	4.07e-16	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MECOMPHF_01229	8.23e-168	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MECOMPHF_01230	2.64e-244	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01231	3.92e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MECOMPHF_01232	1.25e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MECOMPHF_01233	1.62e-57	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MECOMPHF_01234	2.43e-34	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MECOMPHF_01235	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MECOMPHF_01236	5.59e-250	pbpX1	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_01237	7.23e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MECOMPHF_01238	1.2e-44	-	-	-	-	-	-	-	-
MECOMPHF_01239	1.78e-62	-	-	-	C	-	-	-	nitroreductase
MECOMPHF_01240	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MECOMPHF_01241	6.05e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MECOMPHF_01242	1.58e-262	-	-	-	E	ko:K03294	-	ko00000	amino acid
MECOMPHF_01243	1.33e-165	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_01244	4.72e-268	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MECOMPHF_01245	2.82e-315	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MECOMPHF_01247	2.14e-35	-	-	-	-	-	-	-	-
MECOMPHF_01248	7.71e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MECOMPHF_01249	2.9e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MECOMPHF_01250	3.48e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MECOMPHF_01251	1.72e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MECOMPHF_01252	2.77e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MECOMPHF_01253	1.16e-84	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_01254	2e-49	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_01255	4.74e-45	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MECOMPHF_01256	4.17e-77	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
MECOMPHF_01257	2.51e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
MECOMPHF_01258	5.39e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MECOMPHF_01259	9.16e-29	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MECOMPHF_01260	2.38e-59	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MECOMPHF_01261	5.82e-36	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MECOMPHF_01262	4.72e-121	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MECOMPHF_01263	1.65e-81	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MECOMPHF_01264	3.87e-50	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MECOMPHF_01265	7.13e-63	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MECOMPHF_01267	1.22e-308	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MECOMPHF_01268	1.83e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MECOMPHF_01269	9.06e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MECOMPHF_01270	5.75e-261	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
MECOMPHF_01272	2.51e-08	-	-	-	-	-	-	-	-
MECOMPHF_01274	8.1e-104	-	-	-	GM	-	-	-	NAD(P)H-binding
MECOMPHF_01275	1.34e-153	-	-	-	C	-	-	-	Aldo keto reductase
MECOMPHF_01276	3.92e-172	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MECOMPHF_01277	3.7e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MECOMPHF_01279	6.61e-55	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_01280	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MECOMPHF_01281	1.32e-186	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_01282	1.63e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MECOMPHF_01283	1.47e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MECOMPHF_01284	3.78e-56	-	-	-	-	-	-	-	-
MECOMPHF_01285	7.99e-225	degV1	-	-	S	-	-	-	DegV family
MECOMPHF_01286	2.02e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MECOMPHF_01287	0.000255	-	-	-	S	-	-	-	CsbD-like
MECOMPHF_01288	1.31e-35	-	-	-	S	-	-	-	Transglycosylase associated protein
MECOMPHF_01289	6.41e-302	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MECOMPHF_01290	9.29e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MECOMPHF_01292	8.7e-44	-	-	-	-	-	-	-	-
MECOMPHF_01294	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MECOMPHF_01295	1.98e-147	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01296	2.87e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MECOMPHF_01297	1.13e-191	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MECOMPHF_01298	1.37e-28	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MECOMPHF_01299	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_01300	0.0	-	-	-	V	-	-	-	Restriction endonuclease
MECOMPHF_01301	5.94e-46	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_01302	3.17e-37	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_01303	7.87e-194	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_01304	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MECOMPHF_01305	6.36e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MECOMPHF_01306	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MECOMPHF_01307	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MECOMPHF_01308	1.23e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01309	6.26e-307	-	-	-	S	-	-	-	response to antibiotic
MECOMPHF_01310	8.74e-161	-	-	-	-	-	-	-	-
MECOMPHF_01311	7.24e-22	-	-	-	-	-	-	-	-
MECOMPHF_01312	2.34e-241	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MECOMPHF_01313	2.64e-51	-	-	-	-	-	-	-	-
MECOMPHF_01314	6.74e-55	-	-	-	-	-	-	-	-
MECOMPHF_01315	3.03e-13	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MECOMPHF_01316	1.19e-40	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MECOMPHF_01317	4.97e-78	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MECOMPHF_01318	7.83e-38	-	-	-	-	-	-	-	-
MECOMPHF_01319	1.04e-133	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
MECOMPHF_01320	1.83e-180	-	-	-	-	-	-	-	-
MECOMPHF_01321	3.53e-228	-	-	-	-	-	-	-	-
MECOMPHF_01322	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MECOMPHF_01323	1.52e-239	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MECOMPHF_01324	1.15e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MECOMPHF_01325	1.06e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MECOMPHF_01326	6.51e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MECOMPHF_01327	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MECOMPHF_01328	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MECOMPHF_01329	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MECOMPHF_01330	2.46e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MECOMPHF_01331	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MECOMPHF_01332	5.68e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MECOMPHF_01333	1.46e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MECOMPHF_01334	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MECOMPHF_01335	9.14e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MECOMPHF_01336	3.95e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MECOMPHF_01337	1.29e-91	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MECOMPHF_01338	4.31e-280	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MECOMPHF_01339	5.39e-14	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MECOMPHF_01340	2.99e-107	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MECOMPHF_01341	2.8e-67	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MECOMPHF_01342	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MECOMPHF_01343	2.68e-88	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MECOMPHF_01344	8.92e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MECOMPHF_01345	5.87e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MECOMPHF_01346	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MECOMPHF_01347	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MECOMPHF_01348	2.32e-85	-	-	-	-	-	-	-	-
MECOMPHF_01349	1.52e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
MECOMPHF_01350	4.69e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MECOMPHF_01351	2.61e-95	-	-	-	-	-	-	-	-
MECOMPHF_01352	8.57e-61	flaR	-	-	F	-	-	-	topology modulation protein
MECOMPHF_01353	1.35e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MECOMPHF_01354	6.54e-53	-	-	-	-	-	-	-	-
MECOMPHF_01355	2.43e-56	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_01356	3.84e-58	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_01357	2.25e-31	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MECOMPHF_01358	1.45e-43	-	-	-	S	-	-	-	Transglycosylase associated protein
MECOMPHF_01359	1.32e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MECOMPHF_01360	3.95e-170	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MECOMPHF_01361	1.13e-201	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_01362	2.09e-102	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MECOMPHF_01363	8.6e-37	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MECOMPHF_01364	3.03e-19	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MECOMPHF_01365	2.21e-13	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MECOMPHF_01366	2.37e-110	yfhC	-	-	C	-	-	-	nitroreductase
MECOMPHF_01367	3.78e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MECOMPHF_01368	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MECOMPHF_01369	4.14e-08	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MECOMPHF_01370	6.34e-12	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MECOMPHF_01371	1.01e-115	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MECOMPHF_01372	1.08e-127	-	-	-	I	-	-	-	PAP2 superfamily
MECOMPHF_01373	1.07e-145	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MECOMPHF_01375	5.75e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MECOMPHF_01376	3.32e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MECOMPHF_01377	7.3e-22	ps301	-	-	K	-	-	-	sequence-specific DNA binding
MECOMPHF_01378	3.89e-195	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MECOMPHF_01379	5.67e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MECOMPHF_01380	7.12e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MECOMPHF_01381	5.05e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MECOMPHF_01382	5.15e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MECOMPHF_01383	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MECOMPHF_01384	2.42e-74	-	-	-	-	-	-	-	-
MECOMPHF_01385	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MECOMPHF_01386	1.01e-230	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MECOMPHF_01387	2.89e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MECOMPHF_01388	1.63e-62	-	-	-	-	-	-	-	-
MECOMPHF_01389	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MECOMPHF_01390	1.98e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MECOMPHF_01391	7.61e-43	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MECOMPHF_01392	3.32e-28	-	-	-	-	-	-	-	-
MECOMPHF_01393	1.14e-07	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
MECOMPHF_01394	4.94e-130	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MECOMPHF_01395	1.03e-101	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
MECOMPHF_01396	8.19e-107	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
MECOMPHF_01397	2.26e-156	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MECOMPHF_01398	3.84e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MECOMPHF_01399	1.94e-154	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MECOMPHF_01400	1.99e-186	epsB	-	-	M	-	-	-	biosynthesis protein
MECOMPHF_01401	7.05e-248	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MECOMPHF_01402	1.11e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MECOMPHF_01403	4.28e-99	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MECOMPHF_01404	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MECOMPHF_01405	2.4e-76	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MECOMPHF_01406	3.8e-84	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MECOMPHF_01407	1.24e-51	-	-	-	G	-	-	-	MFS/sugar transport protein
MECOMPHF_01408	2.23e-27	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MECOMPHF_01409	1.99e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MECOMPHF_01410	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MECOMPHF_01411	4.53e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MECOMPHF_01412	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MECOMPHF_01413	1.8e-143	-	-	-	-	-	-	-	-
MECOMPHF_01414	9.69e-25	-	-	-	-	-	-	-	-
MECOMPHF_01415	5.56e-21	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MECOMPHF_01416	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MECOMPHF_01417	3.36e-249	ysdE	-	-	P	-	-	-	Citrate transporter
MECOMPHF_01418	2.03e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MECOMPHF_01419	6.68e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MECOMPHF_01420	6.02e-85	-	-	-	L	-	-	-	Helix-turn-helix domain
MECOMPHF_01421	2.95e-24	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MECOMPHF_01422	1.25e-10	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MECOMPHF_01423	4.39e-75	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MECOMPHF_01424	1.22e-221	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MECOMPHF_01425	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01426	1.49e-124	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MECOMPHF_01427	1.75e-225	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MECOMPHF_01428	8.95e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MECOMPHF_01429	3.96e-178	-	-	-	S	-	-	-	Putative threonine/serine exporter
MECOMPHF_01430	0.0	-	-	-	S	-	-	-	ABC transporter
MECOMPHF_01431	9.54e-74	-	-	-	-	-	-	-	-
MECOMPHF_01432	4.37e-111	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MECOMPHF_01433	1.31e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MECOMPHF_01434	9.25e-288	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MECOMPHF_01435	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MECOMPHF_01436	4.43e-56	-	-	-	S	-	-	-	Enterocin A Immunity
MECOMPHF_01437	1.31e-59	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MECOMPHF_01438	1.72e-111	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MECOMPHF_01439	1e-28	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MECOMPHF_01440	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MECOMPHF_01441	4.17e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MECOMPHF_01442	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MECOMPHF_01443	1.03e-206	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MECOMPHF_01444	2.6e-96	-	-	-	-	-	-	-	-
MECOMPHF_01445	1.05e-112	-	-	-	-	-	-	-	-
MECOMPHF_01446	2.69e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MECOMPHF_01447	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MECOMPHF_01448	4.76e-117	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MECOMPHF_01449	5.65e-38	-	-	-	-	-	-	-	-
MECOMPHF_01450	2.39e-164	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MECOMPHF_01451	1.38e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_01452	9.71e-317	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MECOMPHF_01453	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MECOMPHF_01454	4.08e-311	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MECOMPHF_01455	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MECOMPHF_01456	6.46e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MECOMPHF_01457	9.91e-68	-	-	-	-	-	-	-	-
MECOMPHF_01458	3.27e-277	-	-	-	S	-	-	-	Membrane
MECOMPHF_01459	4.13e-35	ykuL	-	-	S	-	-	-	IMP dehydrogenase activity
MECOMPHF_01466	1.19e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MECOMPHF_01467	5.23e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MECOMPHF_01468	1.87e-225	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MECOMPHF_01469	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MECOMPHF_01470	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MECOMPHF_01471	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MECOMPHF_01472	4.52e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MECOMPHF_01473	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MECOMPHF_01474	1.99e-201	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MECOMPHF_01475	1.32e-33	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MECOMPHF_01476	1.79e-66	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MECOMPHF_01477	4.04e-112	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MECOMPHF_01478	4.02e-17	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MECOMPHF_01479	9.1e-93	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MECOMPHF_01480	2.85e-86	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MECOMPHF_01481	1.33e-66	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MECOMPHF_01482	2.22e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MECOMPHF_01483	2.6e-279	-	-	-	S	-	-	-	Sterol carrier protein domain
MECOMPHF_01484	7.88e-27	-	-	-	-	-	-	-	-
MECOMPHF_01485	1.64e-136	-	-	-	K	-	-	-	LysR substrate binding domain
MECOMPHF_01486	1.91e-30	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MECOMPHF_01487	4.86e-233	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MECOMPHF_01488	5.83e-161	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MECOMPHF_01489	1.55e-19	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
MECOMPHF_01490	5.01e-299	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MECOMPHF_01491	5.17e-102	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MECOMPHF_01492	1.14e-91	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MECOMPHF_01493	6.05e-35	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MECOMPHF_01494	7.38e-47	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MECOMPHF_01495	4.85e-270	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MECOMPHF_01496	1.78e-17	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MECOMPHF_01497	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MECOMPHF_01498	4.32e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MECOMPHF_01499	1.11e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MECOMPHF_01500	2.53e-161	-	-	-	S	-	-	-	membrane
MECOMPHF_01501	2.49e-118	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MECOMPHF_01502	3.2e-94	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MECOMPHF_01503	1.38e-129	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_01504	3.09e-66	-	-	-	-	-	-	-	-
MECOMPHF_01505	5.85e-115	-	-	-	-	-	-	-	-
MECOMPHF_01506	3.48e-16	-	-	-	-	-	-	-	-
MECOMPHF_01508	3.63e-46	-	-	-	-	-	-	-	-
MECOMPHF_01512	1.46e-37	-	-	-	-	-	-	-	-
MECOMPHF_01513	2.71e-24	-	-	-	K	-	-	-	transcriptional
MECOMPHF_01514	3.26e-202	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MECOMPHF_01515	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MECOMPHF_01516	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MECOMPHF_01517	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MECOMPHF_01518	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MECOMPHF_01519	8.83e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MECOMPHF_01520	5.3e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MECOMPHF_01521	1.32e-81	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MECOMPHF_01522	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MECOMPHF_01523	2.47e-274	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MECOMPHF_01524	6.64e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MECOMPHF_01525	1.65e-315	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MECOMPHF_01526	7.47e-58	-	-	-	-	-	-	-	-
MECOMPHF_01527	6.49e-53	-	-	-	-	-	-	-	-
MECOMPHF_01528	2.21e-39	-	-	-	-	-	-	-	-
MECOMPHF_01529	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MECOMPHF_01530	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MECOMPHF_01531	2.69e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MECOMPHF_01532	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MECOMPHF_01533	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MECOMPHF_01534	1.08e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MECOMPHF_01535	2.07e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MECOMPHF_01536	9.26e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MECOMPHF_01537	1.26e-91	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MECOMPHF_01538	7.03e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MECOMPHF_01539	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MECOMPHF_01540	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MECOMPHF_01541	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MECOMPHF_01542	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MECOMPHF_01543	0.0	-	-	-	S	-	-	-	membrane
MECOMPHF_01544	1.22e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MECOMPHF_01545	5.84e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MECOMPHF_01546	1.17e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MECOMPHF_01547	5.59e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MECOMPHF_01548	1.14e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MECOMPHF_01549	1.81e-88	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MECOMPHF_01551	2.65e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MECOMPHF_01552	1.46e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MECOMPHF_01553	2.91e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MECOMPHF_01554	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MECOMPHF_01555	2.19e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
MECOMPHF_01556	8.94e-233	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
MECOMPHF_01557	2.95e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MECOMPHF_01558	2.06e-158	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MECOMPHF_01559	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MECOMPHF_01560	7.16e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MECOMPHF_01561	4.46e-226	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MECOMPHF_01562	2.22e-311	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MECOMPHF_01563	5.68e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MECOMPHF_01564	9.64e-218	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MECOMPHF_01565	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MECOMPHF_01566	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MECOMPHF_01567	8.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MECOMPHF_01568	0.000234	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
MECOMPHF_01569	1.42e-78	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MECOMPHF_01570	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MECOMPHF_01571	3.38e-225	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01572	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
MECOMPHF_01573	2.65e-247	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MECOMPHF_01574	1.25e-20	-	-	-	-	-	-	-	-
MECOMPHF_01575	1.87e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MECOMPHF_01576	9.65e-193	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MECOMPHF_01577	6.63e-88	-	-	-	C	-	-	-	Flavodoxin
MECOMPHF_01578	1.97e-21	-	-	-	C	-	-	-	Flavodoxin
MECOMPHF_01579	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MECOMPHF_01580	3.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
MECOMPHF_01581	1.66e-82	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MECOMPHF_01582	1.28e-34	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MECOMPHF_01583	1.23e-120	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MECOMPHF_01584	8.5e-27	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MECOMPHF_01585	1.03e-113	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MECOMPHF_01586	6.01e-54	-	-	-	S	-	-	-	PAS domain
MECOMPHF_01587	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MECOMPHF_01588	2.03e-261	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MECOMPHF_01589	8.55e-47	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
MECOMPHF_01590	2.29e-310	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_01591	5.59e-220	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
MECOMPHF_01592	4.87e-87	-	-	-	S	-	-	-	GtrA-like protein
MECOMPHF_01593	3.23e-175	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MECOMPHF_01594	3.78e-67	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MECOMPHF_01595	3.07e-32	-	-	-	-	-	-	-	-
MECOMPHF_01596	4.26e-132	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MECOMPHF_01597	9.23e-48	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MECOMPHF_01598	2.21e-83	-	-	-	-	-	-	-	-
MECOMPHF_01599	1.2e-20	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_01600	1.28e-164	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MECOMPHF_01601	3.56e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MECOMPHF_01602	1.01e-24	-	-	-	-	-	-	-	-
MECOMPHF_01603	3.5e-166	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MECOMPHF_01604	7.06e-127	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01605	3.45e-79	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01606	1.23e-113	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MECOMPHF_01607	6.67e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MECOMPHF_01608	3.15e-22	-	-	-	-	-	-	-	-
MECOMPHF_01609	1.97e-229	citR	-	-	K	-	-	-	Putative sugar-binding domain
MECOMPHF_01610	5.43e-224	-	-	-	S	-	-	-	Putative threonine/serine exporter
MECOMPHF_01611	6.61e-75	-	-	-	S	-	-	-	Putative threonine/serine exporter
MECOMPHF_01612	1.04e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MECOMPHF_01613	2.45e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MECOMPHF_01614	2.4e-278	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MECOMPHF_01615	2.99e-122	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
MECOMPHF_01616	1.53e-18	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MECOMPHF_01617	2.56e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MECOMPHF_01618	4.67e-95	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MECOMPHF_01619	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MECOMPHF_01623	8.3e-152	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MECOMPHF_01624	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MECOMPHF_01628	5.46e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
MECOMPHF_01629	2.19e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MECOMPHF_01630	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MECOMPHF_01631	1.47e-218	-	-	-	K	-	-	-	Transcriptional regulator
MECOMPHF_01632	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MECOMPHF_01633	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MECOMPHF_01634	2.5e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MECOMPHF_01635	7.31e-115	snf	-	-	KL	-	-	-	domain protein
MECOMPHF_01636	6.61e-64	snf	-	-	KL	-	-	-	domain protein
MECOMPHF_01637	1.7e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MECOMPHF_01638	1.3e-121	-	-	-	K	-	-	-	acetyltransferase
MECOMPHF_01639	1.48e-213	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MECOMPHF_01640	3.81e-121	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MECOMPHF_01641	1.12e-136	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MECOMPHF_01642	3.41e-38	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_01643	5.87e-60	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_01644	3.41e-57	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
MECOMPHF_01645	6.64e-184	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MECOMPHF_01646	3.33e-49	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MECOMPHF_01647	7.24e-65	-	-	-	S	-	-	-	Alpha beta hydrolase
MECOMPHF_01648	2.62e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MECOMPHF_01649	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
MECOMPHF_01651	1.36e-151	-	-	-	L	-	-	-	Integrase
MECOMPHF_01653	7.84e-114	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
MECOMPHF_01654	2.08e-49	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MECOMPHF_01655	5.33e-183	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MECOMPHF_01656	9.08e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
MECOMPHF_01657	3.07e-206	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MECOMPHF_01658	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01659	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MECOMPHF_01660	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MECOMPHF_01661	1.79e-92	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MECOMPHF_01662	1.01e-14	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
MECOMPHF_01663	2.55e-63	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
MECOMPHF_01664	1.9e-126	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
MECOMPHF_01665	7.12e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MECOMPHF_01666	6.54e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MECOMPHF_01667	4.15e-258	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MECOMPHF_01668	8.76e-75	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MECOMPHF_01669	3.18e-160	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
MECOMPHF_01670	9.46e-39	-	-	-	-	-	-	-	-
MECOMPHF_01671	7.65e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MECOMPHF_01672	7.5e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MECOMPHF_01673	2.76e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MECOMPHF_01674	4.33e-173	-	-	-	-	-	-	-	-
MECOMPHF_01675	6.28e-59	-	-	-	-	-	-	-	-
MECOMPHF_01676	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MECOMPHF_01677	2.59e-241	flp	-	-	V	-	-	-	Beta-lactamase
MECOMPHF_01678	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MECOMPHF_01679	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MECOMPHF_01680	4.27e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MECOMPHF_01681	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MECOMPHF_01682	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MECOMPHF_01683	2.75e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MECOMPHF_01684	2.62e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MECOMPHF_01685	3.6e-131	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MECOMPHF_01686	9.52e-27	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MECOMPHF_01687	1.31e-29	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
MECOMPHF_01688	2.65e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MECOMPHF_01689	4.96e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MECOMPHF_01690	1.26e-246	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MECOMPHF_01691	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MECOMPHF_01692	3.22e-213	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
MECOMPHF_01693	4.09e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MECOMPHF_01694	1.26e-42	-	-	-	-	-	-	-	-
MECOMPHF_01695	4.63e-88	-	-	-	-	-	-	-	-
MECOMPHF_01696	2.73e-36	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MECOMPHF_01697	1.01e-62	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MECOMPHF_01698	5.1e-33	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MECOMPHF_01699	5.26e-19	-	-	-	-	-	-	-	-
MECOMPHF_01700	1.03e-131	-	-	-	M	-	-	-	LysM domain protein
MECOMPHF_01701	3.94e-249	-	-	-	D	-	-	-	nuclear chromosome segregation
MECOMPHF_01702	1.54e-141	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MECOMPHF_01703	1.54e-291	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MECOMPHF_01704	1.99e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MECOMPHF_01705	9.54e-152	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MECOMPHF_01706	3.68e-184	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MECOMPHF_01707	2.9e-127	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MECOMPHF_01708	5.39e-175	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
MECOMPHF_01709	3.59e-154	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
MECOMPHF_01710	1.53e-81	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MECOMPHF_01711	2.06e-262	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MECOMPHF_01712	3.69e-187	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MECOMPHF_01713	1.21e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MECOMPHF_01714	7.78e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MECOMPHF_01715	3.71e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MECOMPHF_01716	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MECOMPHF_01717	8.76e-73	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MECOMPHF_01718	6.04e-82	-	-	-	S	-	-	-	Enterocin A Immunity
MECOMPHF_01719	1.42e-170	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MECOMPHF_01720	2.54e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MECOMPHF_01721	4.22e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MECOMPHF_01722	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MECOMPHF_01723	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MECOMPHF_01724	7.09e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MECOMPHF_01725	1.91e-27	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MECOMPHF_01726	2.79e-97	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MECOMPHF_01727	1.43e-303	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MECOMPHF_01728	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MECOMPHF_01729	1.57e-215	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MECOMPHF_01730	9.85e-154	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MECOMPHF_01731	4.55e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MECOMPHF_01732	6.92e-304	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MECOMPHF_01733	6.68e-45	-	-	-	-	-	-	-	-
MECOMPHF_01734	1.1e-62	-	-	-	-	-	-	-	-
MECOMPHF_01735	3.55e-154	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MECOMPHF_01736	6.04e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MECOMPHF_01737	2.23e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MECOMPHF_01738	1.66e-15	-	-	-	M	-	-	-	NlpC/P60 family
MECOMPHF_01739	6.9e-27	-	-	-	M	-	-	-	NlpC/P60 family
MECOMPHF_01740	3.45e-118	-	-	-	M	-	-	-	NlpC/P60 family
MECOMPHF_01741	4e-192	-	-	-	G	-	-	-	Peptidase_C39 like family
MECOMPHF_01743	1.65e-39	-	-	-	-	-	-	-	-
MECOMPHF_01744	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MECOMPHF_01745	1.32e-34	-	-	-	-	-	-	-	-
MECOMPHF_01746	2.98e-185	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MECOMPHF_01747	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MECOMPHF_01748	6.9e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MECOMPHF_01749	4.64e-218	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_01751	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MECOMPHF_01753	4.4e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MECOMPHF_01754	1.15e-178	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MECOMPHF_01757	5.7e-36	-	-	-	-	-	-	-	-
MECOMPHF_01758	1.75e-43	-	-	-	-	-	-	-	-
MECOMPHF_01759	4.23e-45	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MECOMPHF_01760	2.01e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MECOMPHF_01761	7.92e-22	-	-	-	S	-	-	-	Enterocin A Immunity
MECOMPHF_01762	5.21e-145	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MECOMPHF_01763	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MECOMPHF_01764	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MECOMPHF_01765	7.29e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MECOMPHF_01766	1.68e-156	vanR	-	-	K	-	-	-	response regulator
MECOMPHF_01767	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MECOMPHF_01768	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01769	9.24e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MECOMPHF_01770	4.85e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MECOMPHF_01771	6.38e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MECOMPHF_01772	9.33e-196	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MECOMPHF_01773	1.43e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MECOMPHF_01774	3.28e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MECOMPHF_01775	9.37e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MECOMPHF_01776	1.28e-115	cvpA	-	-	S	-	-	-	Colicin V production protein
MECOMPHF_01777	3.16e-231	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MECOMPHF_01778	7.79e-193	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MECOMPHF_01779	4.46e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MECOMPHF_01780	8.37e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MECOMPHF_01781	3.66e-144	-	-	-	K	-	-	-	WHG domain
MECOMPHF_01782	1.16e-51	-	-	-	-	-	-	-	-
MECOMPHF_01783	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MECOMPHF_01784	3.4e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MECOMPHF_01785	7.9e-229	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MECOMPHF_01786	8.42e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MECOMPHF_01787	1.21e-144	-	-	-	G	-	-	-	phosphoglycerate mutase
MECOMPHF_01788	2.4e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MECOMPHF_01789	4.33e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MECOMPHF_01790	2.33e-156	-	-	-	-	-	-	-	-
MECOMPHF_01791	1.09e-119	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MECOMPHF_01792	1.19e-34	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MECOMPHF_01793	9.35e-119	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MECOMPHF_01794	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MECOMPHF_01795	4.12e-79	lysM	-	-	M	-	-	-	LysM domain
MECOMPHF_01796	3e-224	-	-	-	-	-	-	-	-
MECOMPHF_01797	8.98e-283	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MECOMPHF_01798	3.47e-108	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MECOMPHF_01800	5.17e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
MECOMPHF_01801	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MECOMPHF_01802	5.75e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MECOMPHF_01803	4.39e-61	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MECOMPHF_01804	4.59e-40	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MECOMPHF_01806	8.79e-103	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MECOMPHF_01807	1.69e-106	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MECOMPHF_01808	2.66e-59	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
MECOMPHF_01809	1.83e-279	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MECOMPHF_01810	2.5e-263	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MECOMPHF_01811	2.84e-150	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MECOMPHF_01812	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MECOMPHF_01813	4.52e-140	vanZ	-	-	V	-	-	-	VanZ like family
MECOMPHF_01814	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MECOMPHF_01815	6.96e-150	-	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_01816	1.02e-17	-	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_01817	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MECOMPHF_01818	1.32e-55	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
MECOMPHF_01819	2.77e-24	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
MECOMPHF_01820	1.84e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MECOMPHF_01821	5.25e-236	-	-	-	U	-	-	-	FFAT motif binding
MECOMPHF_01822	0.0	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
MECOMPHF_01823	2.67e-84	-	-	-	-	-	-	-	-
MECOMPHF_01825	2.67e-17	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MECOMPHF_01826	2.44e-142	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MECOMPHF_01827	7.09e-15	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MECOMPHF_01828	7.41e-274	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MECOMPHF_01829	3.51e-30	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
MECOMPHF_01830	3.87e-12	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MECOMPHF_01831	4.79e-173	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MECOMPHF_01832	3.69e-180	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MECOMPHF_01833	7.15e-73	-	-	-	-	-	-	-	-
MECOMPHF_01834	7.76e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MECOMPHF_01837	1.3e-199	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MECOMPHF_01838	2.11e-108	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MECOMPHF_01840	4.66e-62	-	-	-	-	-	-	-	-
MECOMPHF_01841	5.43e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MECOMPHF_01842	2.8e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MECOMPHF_01843	6.11e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MECOMPHF_01844	3.46e-275	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MECOMPHF_01845	1.4e-126	-	-	-	-	-	-	-	-
MECOMPHF_01846	8.17e-209	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MECOMPHF_01847	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MECOMPHF_01848	0.0	-	-	-	E	-	-	-	Amino acid permease
MECOMPHF_01849	3.8e-71	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
MECOMPHF_01850	1.42e-166	-	-	-	U	-	-	-	FFAT motif binding
MECOMPHF_01851	1.18e-160	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
MECOMPHF_01852	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MECOMPHF_01853	8e-199	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
MECOMPHF_01855	1.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MECOMPHF_01856	6.8e-115	usp5	-	-	T	-	-	-	universal stress protein
MECOMPHF_01857	1.6e-200	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MECOMPHF_01858	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MECOMPHF_01859	1.91e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MECOMPHF_01860	2.22e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MECOMPHF_01861	3.65e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MECOMPHF_01862	1.05e-108	-	-	-	-	-	-	-	-
MECOMPHF_01863	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MECOMPHF_01864	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MECOMPHF_01865	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MECOMPHF_01867	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MECOMPHF_01868	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MECOMPHF_01869	5.57e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MECOMPHF_01870	6.06e-294	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MECOMPHF_01871	7.66e-292	yttB	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_01872	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MECOMPHF_01873	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MECOMPHF_01874	1.13e-97	-	-	-	-	-	-	-	-
MECOMPHF_01875	1.23e-16	-	-	-	-	-	-	-	-
MECOMPHF_01876	2.09e-41	-	-	-	-	-	-	-	-
MECOMPHF_01877	6.25e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MECOMPHF_01878	8.5e-213	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01880	3.12e-12	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MECOMPHF_01881	9.39e-35	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MECOMPHF_01882	1.14e-128	-	-	-	-	-	-	-	-
MECOMPHF_01883	3.58e-282	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MECOMPHF_01884	1.36e-266	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MECOMPHF_01885	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MECOMPHF_01886	7.07e-170	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
MECOMPHF_01887	1.14e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MECOMPHF_01888	1.82e-154	-	-	-	-	-	-	-	-
MECOMPHF_01889	1.31e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MECOMPHF_01890	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MECOMPHF_01891	1.4e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MECOMPHF_01892	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MECOMPHF_01893	1.54e-84	-	-	-	S	-	-	-	SLAP domain
MECOMPHF_01894	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MECOMPHF_01895	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MECOMPHF_01896	1.24e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MECOMPHF_01897	3.81e-54	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MECOMPHF_01898	4.41e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MECOMPHF_01899	4.98e-273	-	-	-	-	-	-	-	-
MECOMPHF_01902	2.46e-120	-	-	-	-	-	-	-	-
MECOMPHF_01903	1.86e-130	slpX	-	-	S	-	-	-	SLAP domain
MECOMPHF_01904	1.13e-106	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MECOMPHF_01905	4.12e-24	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MECOMPHF_01907	8.57e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MECOMPHF_01908	1.18e-72	-	-	-	-	-	-	-	-
MECOMPHF_01909	3.87e-114	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MECOMPHF_01910	2.19e-69	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MECOMPHF_01911	8.9e-51	-	-	-	-	-	-	-	-
MECOMPHF_01912	1.89e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MECOMPHF_01913	4.25e-28	-	-	-	-	-	-	-	-
MECOMPHF_01914	3.84e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MECOMPHF_01916	1.5e-42	-	-	-	-	-	-	-	-
MECOMPHF_01917	3.27e-53	-	-	-	-	-	-	-	-
MECOMPHF_01918	4.18e-118	-	-	-	L	-	-	-	NUDIX domain
MECOMPHF_01919	5.16e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MECOMPHF_01920	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MECOMPHF_01922	4.93e-142	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MECOMPHF_01923	1.19e-205	-	-	-	-	-	-	-	-
MECOMPHF_01924	1.12e-181	-	-	-	-	-	-	-	-
MECOMPHF_01925	4.25e-173	-	-	-	-	-	-	-	-
MECOMPHF_01926	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MECOMPHF_01927	4.6e-78	ynbB	-	-	P	-	-	-	aluminum resistance
MECOMPHF_01928	2.5e-26	ynbB	-	-	P	-	-	-	aluminum resistance
MECOMPHF_01929	1.63e-32	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MECOMPHF_01930	2.71e-205	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MECOMPHF_01931	5.13e-70	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MECOMPHF_01932	1.21e-122	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MECOMPHF_01933	3.6e-50	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MECOMPHF_01934	3.2e-242	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MECOMPHF_01935	6.31e-295	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
MECOMPHF_01937	1.44e-226	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MECOMPHF_01940	1.06e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MECOMPHF_01941	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MECOMPHF_01942	8.99e-87	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MECOMPHF_01943	1.86e-132	-	-	-	-	-	-	-	-
MECOMPHF_01944	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MECOMPHF_01945	1.07e-49	-	-	-	-	-	-	-	-
MECOMPHF_01946	2.68e-123	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MECOMPHF_01947	1.37e-117	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MECOMPHF_01948	2.54e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MECOMPHF_01949	2.35e-91	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MECOMPHF_01950	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MECOMPHF_01951	6.37e-23	-	-	-	K	-	-	-	Penicillinase repressor
MECOMPHF_01952	1.56e-30	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family