ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HPKECMKP_00018 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HPKECMKP_00019 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
HPKECMKP_00020 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPKECMKP_00021 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPKECMKP_00022 7.84e-265 coiA - - S ko:K06198 - ko00000 Competence protein
HPKECMKP_00023 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HPKECMKP_00024 2.24e-148 yjbH - - Q - - - Thioredoxin
HPKECMKP_00025 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HPKECMKP_00026 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPKECMKP_00027 2.57e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKECMKP_00028 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HPKECMKP_00029 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HPKECMKP_00030 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HPKECMKP_00031 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HPKECMKP_00032 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPKECMKP_00033 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HPKECMKP_00035 1.25e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HPKECMKP_00036 7.16e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HPKECMKP_00037 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPKECMKP_00038 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HPKECMKP_00039 1.43e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HPKECMKP_00040 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
HPKECMKP_00041 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HPKECMKP_00042 2.12e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPKECMKP_00043 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HPKECMKP_00044 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HPKECMKP_00045 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPKECMKP_00046 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPKECMKP_00047 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPKECMKP_00048 4.73e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPKECMKP_00049 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPKECMKP_00050 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPKECMKP_00051 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPKECMKP_00052 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HPKECMKP_00053 2.06e-187 ylmH - - S - - - S4 domain protein
HPKECMKP_00054 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HPKECMKP_00055 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPKECMKP_00056 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPKECMKP_00057 1.18e-123 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HPKECMKP_00058 7.74e-47 - - - - - - - -
HPKECMKP_00059 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPKECMKP_00060 1.5e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HPKECMKP_00061 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HPKECMKP_00062 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPKECMKP_00063 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HPKECMKP_00064 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HPKECMKP_00065 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
HPKECMKP_00066 7.05e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
HPKECMKP_00067 0.0 - - - N - - - domain, Protein
HPKECMKP_00068 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HPKECMKP_00069 1.02e-155 - - - S - - - repeat protein
HPKECMKP_00070 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPKECMKP_00071 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPKECMKP_00072 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HPKECMKP_00073 2.16e-39 - - - - - - - -
HPKECMKP_00074 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HPKECMKP_00075 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPKECMKP_00076 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HPKECMKP_00077 6.45e-111 - - - - - - - -
HPKECMKP_00078 3.25e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPKECMKP_00079 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HPKECMKP_00080 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HPKECMKP_00081 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPKECMKP_00082 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HPKECMKP_00083 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HPKECMKP_00084 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HPKECMKP_00085 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HPKECMKP_00086 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HPKECMKP_00087 1.1e-257 - - - - - - - -
HPKECMKP_00091 1.89e-32 - - - N - - - Cell shape-determining protein MreB
HPKECMKP_00092 7.91e-113 - - - S - - - Pfam Methyltransferase
HPKECMKP_00093 1.16e-127 - - - S - - - Pfam Methyltransferase
HPKECMKP_00094 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKECMKP_00095 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKECMKP_00096 9.32e-40 - - - - - - - -
HPKECMKP_00097 2.14e-122 mraW1 - - J - - - Putative rRNA methylase
HPKECMKP_00098 1.39e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HPKECMKP_00099 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKECMKP_00100 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HPKECMKP_00101 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HPKECMKP_00102 3.03e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPKECMKP_00103 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HPKECMKP_00104 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
HPKECMKP_00105 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HPKECMKP_00106 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_00107 6.16e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_00108 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HPKECMKP_00109 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HPKECMKP_00110 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HPKECMKP_00111 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPKECMKP_00112 1.53e-166 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HPKECMKP_00113 1.53e-164 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HPKECMKP_00115 6.73e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HPKECMKP_00116 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_00117 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HPKECMKP_00119 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPKECMKP_00120 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HPKECMKP_00121 1.64e-151 - - - GM - - - NAD(P)H-binding
HPKECMKP_00122 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPKECMKP_00123 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKECMKP_00124 7.83e-140 - - - - - - - -
HPKECMKP_00125 1.03e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HPKECMKP_00126 5.21e-178 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HPKECMKP_00127 5.37e-74 - - - - - - - -
HPKECMKP_00128 4.56e-78 - - - - - - - -
HPKECMKP_00129 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_00130 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_00131 8.82e-119 - - - - - - - -
HPKECMKP_00132 7.12e-62 - - - - - - - -
HPKECMKP_00133 0.0 uvrA2 - - L - - - ABC transporter
HPKECMKP_00136 4.29e-87 - - - - - - - -
HPKECMKP_00137 9.03e-16 - - - - - - - -
HPKECMKP_00138 1.58e-236 - - - - - - - -
HPKECMKP_00139 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HPKECMKP_00140 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HPKECMKP_00141 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HPKECMKP_00142 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPKECMKP_00143 0.0 - - - S - - - Protein conserved in bacteria
HPKECMKP_00144 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HPKECMKP_00145 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HPKECMKP_00146 2.44e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HPKECMKP_00147 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HPKECMKP_00148 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HPKECMKP_00149 8.41e-314 dinF - - V - - - MatE
HPKECMKP_00150 1.79e-42 - - - - - - - -
HPKECMKP_00153 8.2e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HPKECMKP_00154 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HPKECMKP_00155 4.64e-106 - - - - - - - -
HPKECMKP_00156 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HPKECMKP_00157 6.25e-138 - - - - - - - -
HPKECMKP_00158 1.49e-272 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HPKECMKP_00159 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HPKECMKP_00160 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPKECMKP_00161 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HPKECMKP_00162 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HPKECMKP_00163 9.65e-272 arcT - - E - - - Aminotransferase
HPKECMKP_00164 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HPKECMKP_00165 2.43e-18 - - - - - - - -
HPKECMKP_00166 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HPKECMKP_00167 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
HPKECMKP_00168 4.28e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HPKECMKP_00169 0.0 yhaN - - L - - - AAA domain
HPKECMKP_00170 3.45e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKECMKP_00171 2.73e-278 - - - - - - - -
HPKECMKP_00172 1.45e-234 - - - M - - - Peptidase family S41
HPKECMKP_00173 6.59e-227 - - - K - - - LysR substrate binding domain
HPKECMKP_00174 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HPKECMKP_00175 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKECMKP_00176 4.43e-129 - - - - - - - -
HPKECMKP_00177 4.77e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HPKECMKP_00178 4.68e-235 ykoT - - M - - - Glycosyl transferase family 2
HPKECMKP_00179 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPKECMKP_00180 4.29e-26 - - - S - - - NUDIX domain
HPKECMKP_00181 0.0 - - - S - - - membrane
HPKECMKP_00182 1.73e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPKECMKP_00183 2.05e-109 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HPKECMKP_00184 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPKECMKP_00185 2.04e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPKECMKP_00186 1.31e-78 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HPKECMKP_00187 5.62e-137 - - - - - - - -
HPKECMKP_00188 1.61e-116 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HPKECMKP_00189 9.86e-146 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_00190 2.11e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HPKECMKP_00191 0.0 - - - - - - - -
HPKECMKP_00192 3.57e-76 - - - - - - - -
HPKECMKP_00193 3.36e-248 - - - S - - - Fn3-like domain
HPKECMKP_00194 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_00195 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_00196 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPKECMKP_00197 4.76e-73 - - - - - - - -
HPKECMKP_00198 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HPKECMKP_00199 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00200 2.73e-283 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_00201 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
HPKECMKP_00202 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPKECMKP_00203 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HPKECMKP_00204 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPKECMKP_00205 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HPKECMKP_00206 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HPKECMKP_00207 3.04e-29 - - - S - - - Virus attachment protein p12 family
HPKECMKP_00208 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HPKECMKP_00209 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HPKECMKP_00210 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HPKECMKP_00211 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HPKECMKP_00212 1.57e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPKECMKP_00213 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HPKECMKP_00214 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HPKECMKP_00215 4.52e-241 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HPKECMKP_00216 3.26e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HPKECMKP_00217 2.29e-211 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPKECMKP_00218 6.7e-107 - - - C - - - Flavodoxin
HPKECMKP_00219 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HPKECMKP_00220 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HPKECMKP_00221 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPKECMKP_00222 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HPKECMKP_00223 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
HPKECMKP_00224 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HPKECMKP_00225 9.83e-205 - - - H - - - geranyltranstransferase activity
HPKECMKP_00226 4.32e-233 - - - - - - - -
HPKECMKP_00227 3.67e-65 - - - - - - - -
HPKECMKP_00228 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HPKECMKP_00229 1.04e-244 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HPKECMKP_00230 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
HPKECMKP_00231 8.84e-52 - - - - - - - -
HPKECMKP_00232 2.33e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HPKECMKP_00233 7.33e-110 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HPKECMKP_00234 1.66e-116 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HPKECMKP_00235 1.55e-295 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HPKECMKP_00236 1.34e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HPKECMKP_00237 1.27e-250 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HPKECMKP_00238 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HPKECMKP_00239 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HPKECMKP_00240 5.77e-127 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HPKECMKP_00241 1.89e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HPKECMKP_00242 8.63e-226 - - - - - - - -
HPKECMKP_00243 1.8e-96 - - - - - - - -
HPKECMKP_00244 4.4e-126 - - - S - - - Protein of unknown function (DUF2975)
HPKECMKP_00245 3.86e-38 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_00246 6.99e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HPKECMKP_00247 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPKECMKP_00248 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPKECMKP_00249 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPKECMKP_00250 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPKECMKP_00251 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HPKECMKP_00252 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HPKECMKP_00253 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPKECMKP_00254 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPKECMKP_00255 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HPKECMKP_00256 1.39e-72 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPKECMKP_00257 2.76e-74 - - - - - - - -
HPKECMKP_00258 1.42e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HPKECMKP_00259 7.09e-252 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPKECMKP_00260 1.35e-82 ydeP - - K - - - Transcriptional regulator, HxlR family
HPKECMKP_00261 1.97e-174 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HPKECMKP_00262 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HPKECMKP_00263 1.32e-106 - - - - - - - -
HPKECMKP_00264 1.09e-57 - - - S - - - AAA ATPase domain
HPKECMKP_00269 2.64e-202 - - - J - - - Domain of unknown function (DUF4041)
HPKECMKP_00270 2.73e-97 - - - E - - - IrrE N-terminal-like domain
HPKECMKP_00271 1.38e-82 - - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00272 2.57e-07 - - - K - - - Transcriptional
HPKECMKP_00274 3.41e-41 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HPKECMKP_00278 1.82e-69 - - - - - - - -
HPKECMKP_00279 1.56e-103 - - - - - - - -
HPKECMKP_00282 2.8e-70 - - - S - - - Bacteriophage Mu Gam like protein
HPKECMKP_00283 1.57e-80 - - - - - - - -
HPKECMKP_00284 4.41e-218 - - - L - - - Domain of unknown function (DUF4373)
HPKECMKP_00285 2.2e-65 - - - - - - - -
HPKECMKP_00286 8.72e-111 - - - - - - - -
HPKECMKP_00287 7.47e-88 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HPKECMKP_00289 1.26e-19 - - - S - - - YjzC-like protein
HPKECMKP_00290 9.86e-39 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPKECMKP_00291 6.5e-26 - - - - - - - -
HPKECMKP_00292 3.86e-107 arpU - - S - - - Transcriptional regulator, ArpU family
HPKECMKP_00297 9.25e-20 - - - V - - - HNH nucleases
HPKECMKP_00299 4.48e-85 - - - L ko:K07474 - ko00000 Terminase small subunit
HPKECMKP_00300 0.0 - - - S - - - Phage terminase large subunit
HPKECMKP_00301 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HPKECMKP_00302 9.01e-209 - - - S - - - Phage minor capsid protein 2
HPKECMKP_00304 9.2e-108 - - - S - - - Phage minor structural protein GP20
HPKECMKP_00305 3.36e-237 - - - S - - - viral capsid
HPKECMKP_00306 5.08e-09 - - - - - - - -
HPKECMKP_00307 7.17e-70 - - - S - - - Minor capsid protein
HPKECMKP_00308 1.18e-60 - - - S - - - Minor capsid protein
HPKECMKP_00309 4.06e-84 - - - S - - - Minor capsid protein from bacteriophage
HPKECMKP_00310 4.83e-100 - - - - - - - -
HPKECMKP_00312 2.99e-133 - - - S - - - Bacteriophage Gp15 protein
HPKECMKP_00313 0.0 - - - S - - - peptidoglycan catabolic process
HPKECMKP_00314 5.75e-155 - - - S - - - Phage tail protein
HPKECMKP_00315 2.86e-202 - - - S - - - Prophage endopeptidase tail
HPKECMKP_00317 3.13e-42 - - - E ko:K20306 - ko00000,ko04131 lipolytic protein G-D-S-L family
HPKECMKP_00319 1.73e-47 - - - - - - - -
HPKECMKP_00321 2.66e-07 xhlB - - S - - - SPP1 phage holin
HPKECMKP_00322 4.84e-245 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HPKECMKP_00323 7.86e-65 - - - - - - - -
HPKECMKP_00324 1.18e-66 - - - S - - - Bacteriophage holin
HPKECMKP_00325 2.93e-73 - - - V - - - Abortive infection bacteriophage resistance protein
HPKECMKP_00327 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
HPKECMKP_00328 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
HPKECMKP_00329 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00330 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HPKECMKP_00331 5.37e-182 - - - - - - - -
HPKECMKP_00332 1.33e-77 - - - - - - - -
HPKECMKP_00333 7.74e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HPKECMKP_00334 2.1e-41 - - - - - - - -
HPKECMKP_00335 7.59e-245 ampC - - V - - - Beta-lactamase
HPKECMKP_00336 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HPKECMKP_00337 2.5e-173 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HPKECMKP_00338 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HPKECMKP_00339 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HPKECMKP_00340 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPKECMKP_00341 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPKECMKP_00342 1.03e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPKECMKP_00343 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPKECMKP_00344 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPKECMKP_00345 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HPKECMKP_00346 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HPKECMKP_00347 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPKECMKP_00348 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPKECMKP_00349 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPKECMKP_00350 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPKECMKP_00351 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPKECMKP_00352 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPKECMKP_00353 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HPKECMKP_00354 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPKECMKP_00355 5.63e-131 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPKECMKP_00356 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HPKECMKP_00357 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HPKECMKP_00358 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
HPKECMKP_00359 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HPKECMKP_00360 7.22e-60 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HPKECMKP_00361 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPKECMKP_00362 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_00363 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HPKECMKP_00364 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKECMKP_00365 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
HPKECMKP_00366 3.59e-240 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPKECMKP_00367 3.78e-272 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HPKECMKP_00368 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HPKECMKP_00369 1.57e-205 - - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00370 3.3e-260 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HPKECMKP_00371 2.37e-107 uspA - - T - - - universal stress protein
HPKECMKP_00372 1.34e-52 - - - - - - - -
HPKECMKP_00373 2.08e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HPKECMKP_00374 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HPKECMKP_00375 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_00376 1.83e-141 - - - S - - - Protein of unknown function (DUF1648)
HPKECMKP_00377 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HPKECMKP_00378 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
HPKECMKP_00379 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPKECMKP_00380 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HPKECMKP_00381 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPKECMKP_00382 8.66e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HPKECMKP_00383 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPKECMKP_00384 2.6e-298 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HPKECMKP_00385 5.06e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPKECMKP_00386 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPKECMKP_00387 3.28e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HPKECMKP_00388 3.18e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
HPKECMKP_00389 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HPKECMKP_00390 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HPKECMKP_00391 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HPKECMKP_00392 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HPKECMKP_00393 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HPKECMKP_00394 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HPKECMKP_00395 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00396 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HPKECMKP_00397 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HPKECMKP_00398 8.72e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
HPKECMKP_00399 0.0 ymfH - - S - - - Peptidase M16
HPKECMKP_00400 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HPKECMKP_00401 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPKECMKP_00402 3.83e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HPKECMKP_00403 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPKECMKP_00404 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HPKECMKP_00405 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HPKECMKP_00406 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPKECMKP_00407 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPKECMKP_00408 1.35e-93 - - - - - - - -
HPKECMKP_00409 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HPKECMKP_00410 9.86e-117 - - - - - - - -
HPKECMKP_00411 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPKECMKP_00412 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPKECMKP_00413 4.82e-255 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPKECMKP_00414 2.84e-288 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPKECMKP_00415 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HPKECMKP_00416 5.01e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPKECMKP_00417 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HPKECMKP_00418 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPKECMKP_00419 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPKECMKP_00420 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HPKECMKP_00421 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPKECMKP_00422 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HPKECMKP_00423 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPKECMKP_00424 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPKECMKP_00425 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HPKECMKP_00426 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
HPKECMKP_00427 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HPKECMKP_00428 8.15e-142 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPKECMKP_00429 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HPKECMKP_00430 7.94e-114 ykuL - - S - - - (CBS) domain
HPKECMKP_00431 1.61e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPKECMKP_00432 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPKECMKP_00433 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HPKECMKP_00434 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPKECMKP_00435 1.47e-92 - - - - - - - -
HPKECMKP_00436 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
HPKECMKP_00437 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HPKECMKP_00438 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HPKECMKP_00439 6.48e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
HPKECMKP_00440 6.99e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HPKECMKP_00441 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HPKECMKP_00442 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPKECMKP_00443 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HPKECMKP_00444 5.09e-241 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HPKECMKP_00445 5.66e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HPKECMKP_00446 4.29e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HPKECMKP_00447 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HPKECMKP_00448 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
HPKECMKP_00450 2.22e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HPKECMKP_00451 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPKECMKP_00452 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKECMKP_00453 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
HPKECMKP_00454 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HPKECMKP_00455 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
HPKECMKP_00456 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPKECMKP_00457 3.3e-151 - - - S - - - Protein of unknown function (DUF1461)
HPKECMKP_00458 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HPKECMKP_00459 1.22e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPKECMKP_00460 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HPKECMKP_00461 6.86e-42 - - - - - - - -
HPKECMKP_00462 1.52e-130 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HPKECMKP_00463 9.9e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HPKECMKP_00464 1.31e-132 - - - M - - - Protein of unknown function (DUF3737)
HPKECMKP_00465 3.35e-245 - - - C - - - Aldo/keto reductase family
HPKECMKP_00467 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00468 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00469 6.27e-316 - - - EGP - - - Major Facilitator
HPKECMKP_00473 1.24e-229 yhgE - - V ko:K01421 - ko00000 domain protein
HPKECMKP_00474 1.79e-140 - - - K - - - Transcriptional regulator (TetR family)
HPKECMKP_00475 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_00476 4.17e-195 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HPKECMKP_00477 2.31e-133 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HPKECMKP_00478 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPKECMKP_00479 6.26e-289 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_00480 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HPKECMKP_00481 5.69e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HPKECMKP_00482 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HPKECMKP_00483 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HPKECMKP_00484 1.27e-34 - - - M - - - Host cell surface-exposed lipoprotein
HPKECMKP_00485 2.84e-266 - - - EGP - - - Major facilitator Superfamily
HPKECMKP_00486 4.94e-78 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00487 4.03e-124 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00488 1.44e-226 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HPKECMKP_00489 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
HPKECMKP_00490 2.83e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HPKECMKP_00491 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HPKECMKP_00492 2.85e-206 - - - I - - - alpha/beta hydrolase fold
HPKECMKP_00493 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HPKECMKP_00494 0.0 - - - - - - - -
HPKECMKP_00495 2e-52 - - - S - - - Cytochrome B5
HPKECMKP_00496 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPKECMKP_00497 5.88e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
HPKECMKP_00498 8.07e-163 - - - T - - - Putative diguanylate phosphodiesterase
HPKECMKP_00499 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPKECMKP_00500 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HPKECMKP_00501 6.36e-108 - - - - - - - -
HPKECMKP_00502 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPKECMKP_00503 6.48e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPKECMKP_00504 7.3e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPKECMKP_00505 3.7e-30 - - - - - - - -
HPKECMKP_00506 9.73e-132 - - - - - - - -
HPKECMKP_00507 3.46e-210 - - - K - - - LysR substrate binding domain
HPKECMKP_00508 1.98e-109 - - - P - - - Sodium:sulfate symporter transmembrane region
HPKECMKP_00509 1.77e-187 - - - P - - - Sodium:sulfate symporter transmembrane region
HPKECMKP_00510 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPKECMKP_00511 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HPKECMKP_00512 7.99e-184 - - - S - - - zinc-ribbon domain
HPKECMKP_00514 4.29e-50 - - - - - - - -
HPKECMKP_00515 5.17e-172 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HPKECMKP_00516 4.74e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HPKECMKP_00517 0.0 - - - I - - - acetylesterase activity
HPKECMKP_00518 1.01e-297 - - - M - - - Collagen binding domain
HPKECMKP_00519 3.43e-206 yicL - - EG - - - EamA-like transporter family
HPKECMKP_00520 2.91e-164 - - - E - - - lipolytic protein G-D-S-L family
HPKECMKP_00521 3.53e-227 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HPKECMKP_00522 6.64e-141 - - - K - - - Transcriptional regulator C-terminal region
HPKECMKP_00523 2.23e-60 - - - K - - - HxlR-like helix-turn-helix
HPKECMKP_00524 1.7e-203 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HPKECMKP_00525 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HPKECMKP_00526 1.56e-125 - - - K - - - Transcriptional regulator, MarR family
HPKECMKP_00527 8.08e-154 ydgI3 - - C - - - Nitroreductase family
HPKECMKP_00528 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HPKECMKP_00529 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_00530 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HPKECMKP_00531 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_00532 0.0 - - - - - - - -
HPKECMKP_00533 6.69e-81 - - - - - - - -
HPKECMKP_00534 3.73e-240 - - - S - - - Cell surface protein
HPKECMKP_00535 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_00536 6.39e-123 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HPKECMKP_00537 7.96e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00538 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HPKECMKP_00539 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HPKECMKP_00540 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HPKECMKP_00541 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HPKECMKP_00543 1.15e-43 - - - - - - - -
HPKECMKP_00544 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
HPKECMKP_00545 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HPKECMKP_00546 5.67e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00547 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HPKECMKP_00548 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
HPKECMKP_00549 7.03e-62 - - - - - - - -
HPKECMKP_00550 1.81e-150 - - - S - - - SNARE associated Golgi protein
HPKECMKP_00551 1e-63 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HPKECMKP_00552 2.26e-123 - - - P - - - Cadmium resistance transporter
HPKECMKP_00553 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00554 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HPKECMKP_00555 2.03e-84 - - - - - - - -
HPKECMKP_00556 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HPKECMKP_00557 1.21e-73 - - - - - - - -
HPKECMKP_00558 7.18e-194 - - - K - - - Helix-turn-helix domain
HPKECMKP_00559 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPKECMKP_00560 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPKECMKP_00561 1.5e-303 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_00562 1.33e-18 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_00563 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_00564 1.76e-234 - - - GM - - - Male sterility protein
HPKECMKP_00565 1.21e-98 - - - K - - - helix_turn_helix, mercury resistance
HPKECMKP_00566 2.18e-99 - - - M - - - LysM domain
HPKECMKP_00567 3.03e-130 - - - M - - - Lysin motif
HPKECMKP_00568 1.99e-138 - - - S - - - SdpI/YhfL protein family
HPKECMKP_00569 1.58e-72 nudA - - S - - - ASCH
HPKECMKP_00570 6.73e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HPKECMKP_00571 3.57e-120 - - - - - - - -
HPKECMKP_00572 1.92e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HPKECMKP_00573 5.05e-281 - - - T - - - diguanylate cyclase
HPKECMKP_00574 1.9e-95 - - - S - - - Psort location Cytoplasmic, score
HPKECMKP_00575 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HPKECMKP_00576 2.31e-277 - - - - - - - -
HPKECMKP_00577 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00578 2.85e-26 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00579 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00581 2.65e-289 amd - - E - - - Peptidase family M20/M25/M40
HPKECMKP_00582 2.43e-208 yhxD - - IQ - - - KR domain
HPKECMKP_00584 1.14e-91 - - - - - - - -
HPKECMKP_00585 2.88e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
HPKECMKP_00586 0.0 - - - E - - - Amino Acid
HPKECMKP_00587 1.67e-86 lysM - - M - - - LysM domain
HPKECMKP_00588 1.71e-285 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HPKECMKP_00589 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HPKECMKP_00590 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HPKECMKP_00591 2.04e-56 - - - S - - - Cupredoxin-like domain
HPKECMKP_00592 7.85e-84 - - - S - - - Cupredoxin-like domain
HPKECMKP_00593 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPKECMKP_00594 2.81e-181 - - - K - - - Helix-turn-helix domain
HPKECMKP_00595 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HPKECMKP_00596 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HPKECMKP_00597 0.0 - - - - - - - -
HPKECMKP_00598 2.69e-99 - - - - - - - -
HPKECMKP_00599 7.81e-241 - - - S - - - Cell surface protein
HPKECMKP_00600 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_00601 6.57e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
HPKECMKP_00602 5.83e-87 - - - S - - - Iron-sulphur cluster biosynthesis
HPKECMKP_00603 6.19e-145 - - - S - - - GyrI-like small molecule binding domain
HPKECMKP_00604 4.55e-243 ynjC - - S - - - Cell surface protein
HPKECMKP_00605 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_00606 1.47e-83 - - - - - - - -
HPKECMKP_00607 1.53e-305 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HPKECMKP_00608 4.77e-155 - - - - - - - -
HPKECMKP_00609 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
HPKECMKP_00610 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HPKECMKP_00611 3.64e-272 - - - EGP - - - Major Facilitator
HPKECMKP_00612 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HPKECMKP_00613 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HPKECMKP_00614 6.08e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HPKECMKP_00615 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_00616 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HPKECMKP_00617 4.55e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPKECMKP_00618 1.75e-276 pbpX - - V - - - Beta-lactamase
HPKECMKP_00619 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HPKECMKP_00620 2.9e-139 - - - - - - - -
HPKECMKP_00621 7.62e-97 - - - - - - - -
HPKECMKP_00623 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_00624 6.35e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_00625 3.93e-99 - - - T - - - Universal stress protein family
HPKECMKP_00627 9.46e-315 yfmL - - L - - - DEAD DEAH box helicase
HPKECMKP_00628 1.59e-244 mocA - - S - - - Oxidoreductase
HPKECMKP_00629 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HPKECMKP_00630 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
HPKECMKP_00631 1.83e-184 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HPKECMKP_00632 1.88e-194 gntR - - K - - - rpiR family
HPKECMKP_00633 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_00634 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_00635 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HPKECMKP_00636 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_00637 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPKECMKP_00638 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HPKECMKP_00639 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPKECMKP_00640 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPKECMKP_00641 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPKECMKP_00642 9.48e-263 camS - - S - - - sex pheromone
HPKECMKP_00643 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPKECMKP_00644 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HPKECMKP_00645 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPKECMKP_00646 1.61e-120 yebE - - S - - - UPF0316 protein
HPKECMKP_00647 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPKECMKP_00648 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HPKECMKP_00649 7.78e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HPKECMKP_00650 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HPKECMKP_00651 2.53e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPKECMKP_00652 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
HPKECMKP_00653 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPKECMKP_00654 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPKECMKP_00655 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HPKECMKP_00656 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HPKECMKP_00657 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HPKECMKP_00658 6.07e-33 - - - - - - - -
HPKECMKP_00659 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HPKECMKP_00660 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HPKECMKP_00661 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HPKECMKP_00662 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HPKECMKP_00663 6.5e-215 mleR - - K - - - LysR family
HPKECMKP_00664 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
HPKECMKP_00665 8.08e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HPKECMKP_00666 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKECMKP_00667 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPKECMKP_00668 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HPKECMKP_00669 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HPKECMKP_00670 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HPKECMKP_00671 1.77e-240 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPKECMKP_00672 1.11e-263 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HPKECMKP_00673 8.69e-230 citR - - K - - - sugar-binding domain protein
HPKECMKP_00674 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HPKECMKP_00675 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HPKECMKP_00676 1.18e-66 - - - - - - - -
HPKECMKP_00677 4.26e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HPKECMKP_00678 1.76e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HPKECMKP_00679 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HPKECMKP_00680 3.16e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPKECMKP_00681 5.2e-253 - - - K - - - Helix-turn-helix domain
HPKECMKP_00682 1.49e-225 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HPKECMKP_00683 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HPKECMKP_00684 1.24e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
HPKECMKP_00685 4.43e-278 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HPKECMKP_00686 2.88e-250 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPKECMKP_00687 4.68e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HPKECMKP_00688 4.06e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPKECMKP_00689 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPKECMKP_00690 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HPKECMKP_00691 1.17e-233 - - - S - - - Membrane
HPKECMKP_00692 7e-209 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HPKECMKP_00693 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HPKECMKP_00694 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPKECMKP_00695 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPKECMKP_00696 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKECMKP_00697 2.85e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKECMKP_00698 2.31e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKECMKP_00699 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPKECMKP_00700 3.19e-194 - - - S - - - FMN_bind
HPKECMKP_00701 1.51e-86 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HPKECMKP_00702 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HPKECMKP_00703 5.37e-112 - - - S - - - NusG domain II
HPKECMKP_00704 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HPKECMKP_00705 2.4e-232 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPKECMKP_00706 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HPKECMKP_00707 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKECMKP_00708 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPKECMKP_00709 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPKECMKP_00710 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPKECMKP_00711 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPKECMKP_00712 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPKECMKP_00713 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HPKECMKP_00714 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HPKECMKP_00715 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPKECMKP_00716 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPKECMKP_00717 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPKECMKP_00718 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPKECMKP_00719 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPKECMKP_00720 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPKECMKP_00721 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPKECMKP_00722 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPKECMKP_00723 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HPKECMKP_00724 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPKECMKP_00725 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPKECMKP_00726 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPKECMKP_00727 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPKECMKP_00728 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPKECMKP_00729 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPKECMKP_00730 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HPKECMKP_00731 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPKECMKP_00732 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HPKECMKP_00733 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPKECMKP_00734 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPKECMKP_00735 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPKECMKP_00736 2.57e-150 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HPKECMKP_00737 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKECMKP_00738 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKECMKP_00739 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_00740 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPKECMKP_00741 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HPKECMKP_00751 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPKECMKP_00752 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HPKECMKP_00753 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HPKECMKP_00754 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HPKECMKP_00755 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HPKECMKP_00756 1.7e-118 - - - K - - - Transcriptional regulator
HPKECMKP_00757 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPKECMKP_00758 3.88e-198 - - - I - - - alpha/beta hydrolase fold
HPKECMKP_00759 4.15e-153 - - - I - - - phosphatase
HPKECMKP_00760 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HPKECMKP_00762 1.3e-209 - - - K - - - Transcriptional regulator
HPKECMKP_00763 1.86e-214 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKECMKP_00764 1.2e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HPKECMKP_00765 2.35e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HPKECMKP_00766 2.45e-101 - - - K - - - Winged helix DNA-binding domain
HPKECMKP_00767 0.0 ycaM - - E - - - amino acid
HPKECMKP_00768 6.01e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HPKECMKP_00769 4.3e-44 - - - - - - - -
HPKECMKP_00770 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HPKECMKP_00771 5.44e-198 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HPKECMKP_00772 0.0 - - - M - - - Domain of unknown function (DUF5011)
HPKECMKP_00773 0.0 - - - M - - - Domain of unknown function (DUF5011)
HPKECMKP_00774 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HPKECMKP_00775 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HPKECMKP_00776 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HPKECMKP_00777 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPKECMKP_00778 1.14e-203 - - - EG - - - EamA-like transporter family
HPKECMKP_00779 7.17e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPKECMKP_00780 5.06e-196 - - - S - - - hydrolase
HPKECMKP_00781 7.63e-107 - - - - - - - -
HPKECMKP_00782 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HPKECMKP_00783 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HPKECMKP_00784 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HPKECMKP_00785 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPKECMKP_00786 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HPKECMKP_00787 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_00788 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_00789 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HPKECMKP_00790 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HPKECMKP_00791 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_00792 2.13e-152 - - - K - - - Transcriptional regulator
HPKECMKP_00793 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPKECMKP_00794 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HPKECMKP_00795 2.56e-293 - - - S - - - Sterol carrier protein domain
HPKECMKP_00796 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HPKECMKP_00797 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HPKECMKP_00798 6.58e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HPKECMKP_00799 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HPKECMKP_00800 1.13e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HPKECMKP_00801 2.05e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HPKECMKP_00802 4.72e-40 - - - S - - - Pentapeptide repeats (8 copies)
HPKECMKP_00803 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKECMKP_00804 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HPKECMKP_00805 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HPKECMKP_00807 1.21e-69 - - - - - - - -
HPKECMKP_00808 1.52e-151 - - - - - - - -
HPKECMKP_00809 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HPKECMKP_00810 5.02e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HPKECMKP_00811 4.79e-13 - - - - - - - -
HPKECMKP_00812 1.02e-67 - - - - - - - -
HPKECMKP_00813 1.76e-114 - - - - - - - -
HPKECMKP_00814 5.7e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HPKECMKP_00815 1.08e-47 - - - - - - - -
HPKECMKP_00816 1.1e-103 usp5 - - T - - - universal stress protein
HPKECMKP_00817 3.41e-190 - - - - - - - -
HPKECMKP_00818 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00819 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HPKECMKP_00820 4.76e-56 - - - - - - - -
HPKECMKP_00821 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HPKECMKP_00822 9.74e-177 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00823 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HPKECMKP_00824 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_00825 2.42e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HPKECMKP_00826 1.18e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HPKECMKP_00827 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HPKECMKP_00828 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HPKECMKP_00829 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HPKECMKP_00830 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPKECMKP_00831 1.17e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPKECMKP_00832 9.7e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HPKECMKP_00833 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKECMKP_00834 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKECMKP_00835 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKECMKP_00836 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPKECMKP_00837 2.97e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HPKECMKP_00838 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPKECMKP_00839 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HPKECMKP_00840 2.23e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HPKECMKP_00841 4.17e-163 - - - E - - - Methionine synthase
HPKECMKP_00842 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HPKECMKP_00843 2.62e-121 - - - - - - - -
HPKECMKP_00844 1.46e-198 - - - T - - - EAL domain
HPKECMKP_00845 3.87e-207 - - - GM - - - NmrA-like family
HPKECMKP_00846 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HPKECMKP_00847 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HPKECMKP_00848 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HPKECMKP_00849 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPKECMKP_00850 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HPKECMKP_00851 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPKECMKP_00852 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HPKECMKP_00853 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKECMKP_00854 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPKECMKP_00855 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPKECMKP_00856 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPKECMKP_00857 1.56e-217 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HPKECMKP_00858 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPKECMKP_00859 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HPKECMKP_00860 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
HPKECMKP_00861 1.29e-148 - - - GM - - - NAD(P)H-binding
HPKECMKP_00862 6.68e-207 mleR - - K - - - LysR family
HPKECMKP_00863 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HPKECMKP_00864 3.59e-26 - - - - - - - -
HPKECMKP_00865 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPKECMKP_00866 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKECMKP_00867 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HPKECMKP_00868 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPKECMKP_00869 4.71e-74 - - - S - - - SdpI/YhfL protein family
HPKECMKP_00870 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
HPKECMKP_00871 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
HPKECMKP_00872 1.17e-270 yttB - - EGP - - - Major Facilitator
HPKECMKP_00873 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKECMKP_00874 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HPKECMKP_00875 0.0 yhdP - - S - - - Transporter associated domain
HPKECMKP_00876 2.97e-76 - - - - - - - -
HPKECMKP_00877 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HPKECMKP_00878 1.55e-79 - - - - - - - -
HPKECMKP_00879 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
HPKECMKP_00880 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HPKECMKP_00881 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKECMKP_00882 1.01e-177 - - - - - - - -
HPKECMKP_00883 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPKECMKP_00884 3.53e-169 - - - K - - - Transcriptional regulator
HPKECMKP_00885 3.45e-182 - - - S - - - Putative esterase
HPKECMKP_00886 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HPKECMKP_00887 3.07e-284 - - - M - - - Glycosyl transferases group 1
HPKECMKP_00888 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HPKECMKP_00889 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPKECMKP_00890 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HPKECMKP_00891 1.09e-55 - - - S - - - zinc-ribbon domain
HPKECMKP_00892 3.77e-24 - - - - - - - -
HPKECMKP_00893 1.02e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HPKECMKP_00894 7.2e-103 uspA3 - - T - - - universal stress protein
HPKECMKP_00895 7.98e-65 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPKECMKP_00896 2.52e-179 - - - S - - - Putative threonine/serine exporter
HPKECMKP_00897 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HPKECMKP_00898 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HPKECMKP_00899 1.65e-106 - - - S - - - ASCH
HPKECMKP_00900 1.77e-164 - - - F - - - glutamine amidotransferase
HPKECMKP_00901 3.78e-33 - - - K - - - WYL domain
HPKECMKP_00902 1.47e-72 - - - K - - - WYL domain
HPKECMKP_00903 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPKECMKP_00904 0.0 fusA1 - - J - - - elongation factor G
HPKECMKP_00905 8.07e-164 - - - S - - - Protein of unknown function
HPKECMKP_00906 2.12e-195 - - - EG - - - EamA-like transporter family
HPKECMKP_00907 7.65e-121 yfbM - - K - - - FR47-like protein
HPKECMKP_00908 1.15e-161 - - - S - - - DJ-1/PfpI family
HPKECMKP_00909 1.98e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HPKECMKP_00910 7.81e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_00911 2.23e-297 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HPKECMKP_00912 1.73e-217 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HPKECMKP_00913 5.24e-179 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HPKECMKP_00914 2.38e-99 - - - - - - - -
HPKECMKP_00915 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HPKECMKP_00916 5.67e-179 - - - - - - - -
HPKECMKP_00917 4.07e-05 - - - - - - - -
HPKECMKP_00918 7.41e-182 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HPKECMKP_00919 1.67e-54 - - - - - - - -
HPKECMKP_00920 3.02e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_00921 6.89e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HPKECMKP_00922 1.29e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HPKECMKP_00923 1.45e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
HPKECMKP_00924 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HPKECMKP_00925 1.86e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
HPKECMKP_00926 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPKECMKP_00927 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
HPKECMKP_00928 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_00929 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
HPKECMKP_00930 3.94e-224 - - - C - - - Zinc-binding dehydrogenase
HPKECMKP_00931 1.79e-173 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPKECMKP_00932 4.13e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HPKECMKP_00933 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPKECMKP_00934 1.69e-260 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HPKECMKP_00935 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HPKECMKP_00936 0.0 - - - L - - - HIRAN domain
HPKECMKP_00937 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HPKECMKP_00938 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HPKECMKP_00939 3.13e-160 - - - - - - - -
HPKECMKP_00940 5.08e-192 - - - I - - - Alpha/beta hydrolase family
HPKECMKP_00941 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HPKECMKP_00942 8.08e-185 - - - F - - - Phosphorylase superfamily
HPKECMKP_00943 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HPKECMKP_00944 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HPKECMKP_00945 1.27e-98 - - - K - - - Transcriptional regulator
HPKECMKP_00946 3.28e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HPKECMKP_00947 2.19e-289 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HPKECMKP_00948 2.21e-65 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_00949 9.31e-273 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HPKECMKP_00951 3.07e-204 morA - - S - - - reductase
HPKECMKP_00952 3.34e-212 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HPKECMKP_00953 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HPKECMKP_00954 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HPKECMKP_00955 5.05e-114 - - - - - - - -
HPKECMKP_00956 0.0 - - - - - - - -
HPKECMKP_00957 2.17e-266 - - - C - - - Oxidoreductase
HPKECMKP_00958 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HPKECMKP_00959 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_00960 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HPKECMKP_00962 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HPKECMKP_00963 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
HPKECMKP_00964 3.01e-180 - - - - - - - -
HPKECMKP_00965 1.1e-191 - - - - - - - -
HPKECMKP_00966 3.37e-115 - - - - - - - -
HPKECMKP_00967 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HPKECMKP_00968 6.03e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_00969 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HPKECMKP_00970 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_00971 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HPKECMKP_00972 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
HPKECMKP_00974 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_00975 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HPKECMKP_00976 2.24e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HPKECMKP_00977 3.9e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HPKECMKP_00978 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HPKECMKP_00979 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_00980 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKECMKP_00981 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HPKECMKP_00982 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HPKECMKP_00983 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HPKECMKP_00984 1.52e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_00985 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_00986 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
HPKECMKP_00987 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HPKECMKP_00988 5.75e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPKECMKP_00989 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HPKECMKP_00990 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HPKECMKP_00991 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HPKECMKP_00992 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HPKECMKP_00993 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HPKECMKP_00994 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_00995 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HPKECMKP_00996 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKECMKP_00997 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HPKECMKP_00998 1.16e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HPKECMKP_00999 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HPKECMKP_01000 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HPKECMKP_01001 1.72e-212 mleR - - K - - - LysR substrate binding domain
HPKECMKP_01003 2.91e-55 - - - M - - - domain protein
HPKECMKP_01005 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HPKECMKP_01006 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HPKECMKP_01007 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HPKECMKP_01008 5.35e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HPKECMKP_01009 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKECMKP_01010 7.18e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPKECMKP_01011 9.51e-148 pgm1 - - G - - - phosphoglycerate mutase
HPKECMKP_01012 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HPKECMKP_01013 6.33e-46 - - - - - - - -
HPKECMKP_01014 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
HPKECMKP_01015 1.46e-206 fbpA - - K - - - Domain of unknown function (DUF814)
HPKECMKP_01016 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPKECMKP_01017 3.81e-18 - - - - - - - -
HPKECMKP_01018 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPKECMKP_01019 2.31e-73 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPKECMKP_01020 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_01021 4.83e-64 - - - - - - - -
HPKECMKP_01022 1.28e-77 - - - - - - - -
HPKECMKP_01023 1.86e-210 - - - - - - - -
HPKECMKP_01024 1.4e-95 - - - K - - - Transcriptional regulator
HPKECMKP_01025 0.0 pepF2 - - E - - - Oligopeptidase F
HPKECMKP_01026 6.56e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
HPKECMKP_01027 7.2e-61 - - - S - - - Enterocin A Immunity
HPKECMKP_01028 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HPKECMKP_01029 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_01030 2.66e-172 - - - - - - - -
HPKECMKP_01031 9.38e-139 pncA - - Q - - - Isochorismatase family
HPKECMKP_01032 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPKECMKP_01033 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKECMKP_01034 8.97e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HPKECMKP_01035 2.48e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HPKECMKP_01036 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
HPKECMKP_01037 1.48e-201 ccpB - - K - - - lacI family
HPKECMKP_01038 1.27e-156 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKECMKP_01039 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPKECMKP_01040 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HPKECMKP_01041 4.26e-127 - - - C - - - Nitroreductase family
HPKECMKP_01042 4.08e-215 - - - S - - - Polyphosphate kinase 2 (PPK2)
HPKECMKP_01043 4.16e-216 - - - S - - - domain, Protein
HPKECMKP_01044 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_01045 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HPKECMKP_01046 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HPKECMKP_01047 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPKECMKP_01048 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
HPKECMKP_01049 0.0 - - - M - - - domain protein
HPKECMKP_01050 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HPKECMKP_01051 5.14e-143 - - - S - - - Protein of unknown function (DUF1211)
HPKECMKP_01052 4.15e-46 - - - - - - - -
HPKECMKP_01053 9.88e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPKECMKP_01054 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPKECMKP_01055 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
HPKECMKP_01056 2.83e-66 - - - S - - - Domain of unknown function (DU1801)
HPKECMKP_01057 1.47e-212 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HPKECMKP_01058 3.05e-282 ysaA - - V - - - RDD family
HPKECMKP_01059 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HPKECMKP_01060 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPKECMKP_01061 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPKECMKP_01062 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPKECMKP_01063 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HPKECMKP_01064 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPKECMKP_01065 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPKECMKP_01066 5.18e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPKECMKP_01067 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPKECMKP_01068 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HPKECMKP_01069 4.3e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPKECMKP_01070 7.09e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HPKECMKP_01071 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
HPKECMKP_01072 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HPKECMKP_01073 4.54e-54 - - - - - - - -
HPKECMKP_01075 8.83e-317 - - - EGP - - - Major Facilitator
HPKECMKP_01076 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HPKECMKP_01077 4.26e-109 cvpA - - S - - - Colicin V production protein
HPKECMKP_01078 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPKECMKP_01079 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPKECMKP_01080 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HPKECMKP_01081 1.83e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HPKECMKP_01082 1.93e-132 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HPKECMKP_01083 1.37e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HPKECMKP_01084 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HPKECMKP_01085 8.03e-28 - - - - - - - -
HPKECMKP_01086 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HPKECMKP_01087 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_01088 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HPKECMKP_01089 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HPKECMKP_01090 3.85e-76 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HPKECMKP_01091 9.71e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HPKECMKP_01092 5.14e-227 ydbI - - K - - - AI-2E family transporter
HPKECMKP_01093 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPKECMKP_01094 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HPKECMKP_01096 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HPKECMKP_01097 7.66e-106 - - - - - - - -
HPKECMKP_01098 2.74e-77 - - - S - - - Protein of unknown function (DUF1211)
HPKECMKP_01099 7.91e-187 - - - S ko:K01421 - ko00000 ABC-2 family transporter protein
HPKECMKP_01100 1.18e-82 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_01102 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPKECMKP_01103 2.5e-188 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HPKECMKP_01104 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPKECMKP_01105 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPKECMKP_01106 1.75e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPKECMKP_01107 2.49e-73 - - - S - - - Enterocin A Immunity
HPKECMKP_01108 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HPKECMKP_01109 7.91e-249 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HPKECMKP_01110 3.04e-231 - - - D ko:K06889 - ko00000 Alpha beta
HPKECMKP_01111 8.78e-205 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HPKECMKP_01112 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HPKECMKP_01113 1.21e-151 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HPKECMKP_01114 1.03e-34 - - - - - - - -
HPKECMKP_01115 4.48e-185 WQ51_01275 - - S - - - EDD domain protein, DegV family
HPKECMKP_01116 4.78e-163 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HPKECMKP_01117 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HPKECMKP_01118 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HPKECMKP_01119 1.54e-214 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HPKECMKP_01120 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
HPKECMKP_01121 1.74e-53 - - - S - - - Enterocin A Immunity
HPKECMKP_01122 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HPKECMKP_01123 3.32e-135 - - - - - - - -
HPKECMKP_01124 4.88e-303 - - - S - - - module of peptide synthetase
HPKECMKP_01125 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
HPKECMKP_01127 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HPKECMKP_01128 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_01129 1.25e-198 - - - GM - - - NmrA-like family
HPKECMKP_01130 1.08e-102 - - - K - - - MerR family regulatory protein
HPKECMKP_01131 1.44e-189 - - - S - - - haloacid dehalogenase-like hydrolase
HPKECMKP_01132 2.31e-195 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HPKECMKP_01133 6.26e-101 - - - - - - - -
HPKECMKP_01134 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPKECMKP_01135 2.51e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_01136 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HPKECMKP_01137 3.73e-263 - - - S - - - DUF218 domain
HPKECMKP_01138 2.6e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HPKECMKP_01139 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HPKECMKP_01140 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_01141 3.77e-199 - - - S - - - Putative adhesin
HPKECMKP_01142 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
HPKECMKP_01143 1.72e-69 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_01144 7.25e-126 - - - KT - - - response to antibiotic
HPKECMKP_01145 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HPKECMKP_01146 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01147 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_01148 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HPKECMKP_01149 5.93e-302 - - - EK - - - Aminotransferase, class I
HPKECMKP_01150 3.36e-216 - - - K - - - LysR substrate binding domain
HPKECMKP_01151 5.43e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_01152 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HPKECMKP_01153 6.06e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HPKECMKP_01154 3.36e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HPKECMKP_01155 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HPKECMKP_01156 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HPKECMKP_01157 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HPKECMKP_01158 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPKECMKP_01159 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HPKECMKP_01160 2.02e-269 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPKECMKP_01161 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPKECMKP_01162 2.3e-159 - - - S - - - Protein of unknown function (DUF1275)
HPKECMKP_01163 1.14e-159 vanR - - K - - - response regulator
HPKECMKP_01164 6.55e-272 hpk31 - - T - - - Histidine kinase
HPKECMKP_01165 2.18e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HPKECMKP_01166 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HPKECMKP_01167 2.05e-167 - - - E - - - branched-chain amino acid
HPKECMKP_01168 5.93e-73 - - - S - - - branched-chain amino acid
HPKECMKP_01169 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
HPKECMKP_01170 2.12e-72 - - - - - - - -
HPKECMKP_01171 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
HPKECMKP_01172 7.09e-125 - - - S - - - Domain of unknown function (DUF4352)
HPKECMKP_01173 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
HPKECMKP_01174 2.36e-259 pkn2 - - KLT - - - Protein tyrosine kinase
HPKECMKP_01175 8.15e-211 - - - - - - - -
HPKECMKP_01176 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HPKECMKP_01177 2.54e-55 - - - - - - - -
HPKECMKP_01178 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HPKECMKP_01179 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPKECMKP_01180 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPKECMKP_01181 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPKECMKP_01182 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HPKECMKP_01183 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPKECMKP_01184 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HPKECMKP_01185 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HPKECMKP_01187 7.72e-57 yabO - - J - - - S4 domain protein
HPKECMKP_01188 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HPKECMKP_01189 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPKECMKP_01190 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPKECMKP_01191 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HPKECMKP_01192 0.0 - - - S - - - Putative peptidoglycan binding domain
HPKECMKP_01193 4.87e-148 - - - S - - - (CBS) domain
HPKECMKP_01194 1.3e-110 queT - - S - - - QueT transporter
HPKECMKP_01195 1.07e-240 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPKECMKP_01196 1.9e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HPKECMKP_01197 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HPKECMKP_01198 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPKECMKP_01199 2.09e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPKECMKP_01200 3.55e-258 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HPKECMKP_01201 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKECMKP_01202 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HPKECMKP_01203 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HPKECMKP_01204 1.31e-86 - - - L - - - Transposase DDE domain
HPKECMKP_01205 4.39e-85 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HPKECMKP_01206 8.29e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPKECMKP_01207 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPKECMKP_01208 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPKECMKP_01209 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPKECMKP_01210 1.84e-189 - - - - - - - -
HPKECMKP_01211 4.58e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HPKECMKP_01212 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
HPKECMKP_01213 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HPKECMKP_01214 5.19e-274 - - - J - - - translation release factor activity
HPKECMKP_01215 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HPKECMKP_01216 1.26e-305 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPKECMKP_01217 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPKECMKP_01218 1.15e-35 - - - - - - - -
HPKECMKP_01219 6.59e-170 - - - S - - - YheO-like PAS domain
HPKECMKP_01220 1.14e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPKECMKP_01221 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HPKECMKP_01222 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HPKECMKP_01223 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPKECMKP_01224 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPKECMKP_01225 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPKECMKP_01226 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HPKECMKP_01227 2.46e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HPKECMKP_01228 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HPKECMKP_01229 1.45e-191 yxeH - - S - - - hydrolase
HPKECMKP_01230 3.53e-178 - - - - - - - -
HPKECMKP_01231 1.82e-232 - - - S - - - DUF218 domain
HPKECMKP_01232 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPKECMKP_01233 2.82e-196 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HPKECMKP_01234 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPKECMKP_01235 3.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HPKECMKP_01236 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HPKECMKP_01237 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HPKECMKP_01238 1.1e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HPKECMKP_01239 1.07e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPKECMKP_01240 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HPKECMKP_01241 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPKECMKP_01242 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPKECMKP_01243 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HPKECMKP_01244 1.49e-272 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HPKECMKP_01245 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPKECMKP_01246 5.43e-91 - - - F - - - DNA mismatch repair protein MutT
HPKECMKP_01247 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HPKECMKP_01248 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HPKECMKP_01249 4.65e-229 - - - - - - - -
HPKECMKP_01250 1.32e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HPKECMKP_01251 2.35e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKECMKP_01252 5.93e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPKECMKP_01253 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
HPKECMKP_01254 2e-208 - - - GK - - - ROK family
HPKECMKP_01255 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_01256 1.84e-316 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_01257 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
HPKECMKP_01258 9.68e-34 - - - - - - - -
HPKECMKP_01259 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_01260 1.56e-165 - - - K - - - UbiC transcription regulator-associated domain protein
HPKECMKP_01261 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKECMKP_01262 2.05e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HPKECMKP_01263 0.0 - - - L - - - DNA helicase
HPKECMKP_01264 9.15e-41 - - - - - - - -
HPKECMKP_01265 3.08e-265 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HPKECMKP_01266 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HPKECMKP_01267 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HPKECMKP_01268 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPKECMKP_01269 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPKECMKP_01270 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPKECMKP_01271 3.55e-08 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HPKECMKP_01272 6.2e-09 - - - - - - - -
HPKECMKP_01273 6.69e-26 - - - - - - - -
HPKECMKP_01274 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HPKECMKP_01275 2.51e-103 - - - T - - - Universal stress protein family
HPKECMKP_01276 5.03e-128 padR - - K - - - Virulence activator alpha C-term
HPKECMKP_01277 3.7e-133 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HPKECMKP_01278 1.32e-181 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HPKECMKP_01279 2.04e-110 - - - K - - - Acetyltransferase (GNAT) domain
HPKECMKP_01280 6.39e-200 degV1 - - S - - - DegV family
HPKECMKP_01281 1.21e-72 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HPKECMKP_01282 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HPKECMKP_01284 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HPKECMKP_01285 0.0 - - - - - - - -
HPKECMKP_01287 9.06e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
HPKECMKP_01288 1.31e-143 - - - S - - - Cell surface protein
HPKECMKP_01289 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPKECMKP_01290 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPKECMKP_01291 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
HPKECMKP_01292 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPKECMKP_01293 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPKECMKP_01294 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPKECMKP_01295 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPKECMKP_01296 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HPKECMKP_01297 1.03e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPKECMKP_01298 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPKECMKP_01299 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPKECMKP_01300 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HPKECMKP_01301 4.91e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPKECMKP_01302 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPKECMKP_01303 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HPKECMKP_01304 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HPKECMKP_01305 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HPKECMKP_01306 4.96e-289 yttB - - EGP - - - Major Facilitator
HPKECMKP_01307 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPKECMKP_01308 7.65e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPKECMKP_01310 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HPKECMKP_01311 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPKECMKP_01312 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPKECMKP_01313 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HPKECMKP_01314 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HPKECMKP_01315 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPKECMKP_01316 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HPKECMKP_01318 2.4e-183 - - - S - - - haloacid dehalogenase-like hydrolase
HPKECMKP_01319 2.22e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HPKECMKP_01320 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HPKECMKP_01321 2.54e-43 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HPKECMKP_01322 5.31e-28 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HPKECMKP_01323 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
HPKECMKP_01324 2.54e-50 - - - - - - - -
HPKECMKP_01326 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HPKECMKP_01327 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKECMKP_01328 1.44e-312 yycH - - S - - - YycH protein
HPKECMKP_01329 3.79e-190 yycI - - S - - - YycH protein
HPKECMKP_01330 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HPKECMKP_01331 3.02e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HPKECMKP_01332 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPKECMKP_01333 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_01334 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
HPKECMKP_01335 1.2e-214 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HPKECMKP_01336 4.91e-156 ung2 - - L - - - Uracil-DNA glycosylase
HPKECMKP_01337 6.59e-17 pnb - - C - - - nitroreductase
HPKECMKP_01338 6.55e-85 pnb - - C - - - nitroreductase
HPKECMKP_01339 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HPKECMKP_01340 1.83e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
HPKECMKP_01341 0.0 - - - C - - - FMN_bind
HPKECMKP_01342 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HPKECMKP_01343 1.7e-203 - - - K - - - LysR family
HPKECMKP_01344 5.88e-94 - - - C - - - FMN binding
HPKECMKP_01345 1.02e-94 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPKECMKP_01346 1.17e-210 - - - S - - - KR domain
HPKECMKP_01347 2.73e-202 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HPKECMKP_01348 1.46e-156 ydgI - - C - - - Nitroreductase family
HPKECMKP_01349 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HPKECMKP_01350 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HPKECMKP_01351 1.48e-149 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPKECMKP_01352 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HPKECMKP_01353 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
HPKECMKP_01354 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HPKECMKP_01355 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HPKECMKP_01356 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HPKECMKP_01357 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HPKECMKP_01358 7.17e-85 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HPKECMKP_01359 1.05e-94 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HPKECMKP_01360 1.36e-209 yvgN - - C - - - Aldo keto reductase
HPKECMKP_01361 2.57e-171 - - - S - - - Putative threonine/serine exporter
HPKECMKP_01362 2.93e-102 - - - S - - - Threonine/Serine exporter, ThrE
HPKECMKP_01363 3.68e-57 - - - S - - - Protein of unknown function (DUF1093)
HPKECMKP_01364 5.43e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPKECMKP_01365 4.88e-117 ymdB - - S - - - Macro domain protein
HPKECMKP_01366 5.31e-123 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HPKECMKP_01367 1.58e-66 - - - - - - - -
HPKECMKP_01368 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
HPKECMKP_01369 0.0 - - - - - - - -
HPKECMKP_01370 7.89e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
HPKECMKP_01371 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_01372 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPKECMKP_01373 1.31e-114 - - - K - - - Winged helix DNA-binding domain
HPKECMKP_01374 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_01375 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HPKECMKP_01376 4.45e-38 - - - - - - - -
HPKECMKP_01377 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HPKECMKP_01378 1.88e-96 - - - M - - - PFAM NLP P60 protein
HPKECMKP_01379 6.18e-71 - - - - - - - -
HPKECMKP_01380 1.93e-79 - - - - - - - -
HPKECMKP_01383 5.89e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HPKECMKP_01384 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPKECMKP_01385 2.05e-163 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HPKECMKP_01386 2.41e-233 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HPKECMKP_01387 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HPKECMKP_01388 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_01389 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HPKECMKP_01390 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
HPKECMKP_01392 8.33e-66 - - - F - - - NUDIX domain
HPKECMKP_01393 1.01e-26 - - - - - - - -
HPKECMKP_01394 4.27e-126 dpsB - - P - - - Belongs to the Dps family
HPKECMKP_01395 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HPKECMKP_01396 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HPKECMKP_01397 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HPKECMKP_01398 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPKECMKP_01399 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HPKECMKP_01400 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HPKECMKP_01401 1.83e-235 - - - S - - - Cell surface protein
HPKECMKP_01402 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_01403 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HPKECMKP_01404 7.83e-60 - - - - - - - -
HPKECMKP_01405 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HPKECMKP_01406 1.03e-65 - - - - - - - -
HPKECMKP_01407 9.34e-317 - - - S - - - Putative metallopeptidase domain
HPKECMKP_01408 1.64e-282 - - - S - - - associated with various cellular activities
HPKECMKP_01409 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_01410 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HPKECMKP_01411 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HPKECMKP_01412 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HPKECMKP_01413 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HPKECMKP_01414 2.84e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_01415 2.31e-95 - - - M - - - LysM domain protein
HPKECMKP_01416 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HPKECMKP_01417 4.29e-227 - - - - - - - -
HPKECMKP_01418 2.8e-169 - - - - - - - -
HPKECMKP_01419 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HPKECMKP_01420 2.04e-73 - - - - - - - -
HPKECMKP_01421 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPKECMKP_01422 1.08e-101 - - - S ko:K02348 - ko00000 GNAT family
HPKECMKP_01423 1.24e-99 - - - K - - - Transcriptional regulator
HPKECMKP_01424 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HPKECMKP_01425 2.18e-53 - - - - - - - -
HPKECMKP_01426 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_01427 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_01428 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_01429 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPKECMKP_01430 4.3e-124 - - - K - - - Cupin domain
HPKECMKP_01431 1.15e-109 - - - S - - - ASCH
HPKECMKP_01432 1.88e-111 - - - K - - - GNAT family
HPKECMKP_01433 2.92e-115 - - - K - - - acetyltransferase
HPKECMKP_01434 2.06e-30 - - - - - - - -
HPKECMKP_01435 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HPKECMKP_01436 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_01437 1.08e-243 - - - - - - - -
HPKECMKP_01438 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HPKECMKP_01439 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HPKECMKP_01441 1.12e-303 xylP1 - - G - - - MFS/sugar transport protein
HPKECMKP_01442 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HPKECMKP_01443 2.97e-41 - - - - - - - -
HPKECMKP_01444 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKECMKP_01445 6.4e-54 - - - - - - - -
HPKECMKP_01446 3.62e-122 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HPKECMKP_01447 4.28e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPKECMKP_01448 1.45e-79 - - - S - - - CHY zinc finger
HPKECMKP_01449 8.69e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
HPKECMKP_01450 1.13e-157 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPKECMKP_01451 4.45e-116 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_01452 1.14e-186 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPKECMKP_01453 3.43e-281 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKECMKP_01454 1.57e-280 - - - - - - - -
HPKECMKP_01455 4.7e-198 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HPKECMKP_01456 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPKECMKP_01457 3.93e-59 - - - - - - - -
HPKECMKP_01458 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
HPKECMKP_01459 0.0 - - - P - - - Major Facilitator Superfamily
HPKECMKP_01460 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HPKECMKP_01461 9e-227 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKECMKP_01462 8.95e-60 - - - - - - - -
HPKECMKP_01463 6.06e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
HPKECMKP_01464 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPKECMKP_01465 0.0 sufI - - Q - - - Multicopper oxidase
HPKECMKP_01466 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HPKECMKP_01467 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HPKECMKP_01468 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HPKECMKP_01469 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HPKECMKP_01470 1.52e-103 - - - - - - - -
HPKECMKP_01471 1.46e-100 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPKECMKP_01472 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HPKECMKP_01473 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKECMKP_01474 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HPKECMKP_01475 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPKECMKP_01476 1.1e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01477 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HPKECMKP_01478 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPKECMKP_01479 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HPKECMKP_01480 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HPKECMKP_01481 0.0 - - - M - - - domain protein
HPKECMKP_01482 6e-54 - - - - - - - -
HPKECMKP_01483 2.92e-161 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HPKECMKP_01484 7e-123 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HPKECMKP_01485 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
HPKECMKP_01486 1.28e-45 - - - - - - - -
HPKECMKP_01487 2.78e-192 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HPKECMKP_01488 5.8e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HPKECMKP_01489 1.07e-135 - - - GM - - - NAD(P)H-binding
HPKECMKP_01490 6.67e-204 - - - K - - - LysR substrate binding domain
HPKECMKP_01491 1.75e-82 - - - S - - - Domain of unknown function (DUF4440)
HPKECMKP_01492 1.56e-144 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HPKECMKP_01493 2.81e-64 - - - - - - - -
HPKECMKP_01494 9.76e-50 - - - - - - - -
HPKECMKP_01495 1.08e-112 yvbK - - K - - - GNAT family
HPKECMKP_01496 9.82e-111 - - - - - - - -
HPKECMKP_01497 9.14e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HPKECMKP_01498 2e-148 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HPKECMKP_01499 5.27e-140 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HPKECMKP_01500 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPKECMKP_01502 1.17e-154 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01503 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HPKECMKP_01504 4.35e-301 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HPKECMKP_01505 1.27e-103 - - - K - - - transcriptional regulator, MerR family
HPKECMKP_01506 4.77e-100 yphH - - S - - - Cupin domain
HPKECMKP_01507 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HPKECMKP_01508 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKECMKP_01509 5.31e-267 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HPKECMKP_01510 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01511 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HPKECMKP_01512 4.13e-62 - - - M - - - LysM domain
HPKECMKP_01514 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKECMKP_01515 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HPKECMKP_01516 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_01517 4.38e-222 - - - S - - - Conserved hypothetical protein 698
HPKECMKP_01518 6.08e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPKECMKP_01519 2.43e-105 - - - S - - - Domain of unknown function (DUF4811)
HPKECMKP_01520 3.65e-46 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKECMKP_01521 4.95e-271 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKECMKP_01522 5.94e-162 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HPKECMKP_01523 1.41e-250 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_01524 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HPKECMKP_01525 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HPKECMKP_01526 9.01e-155 - - - S - - - Membrane
HPKECMKP_01527 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPKECMKP_01528 2.92e-126 ywjB - - H - - - RibD C-terminal domain
HPKECMKP_01529 4.9e-239 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HPKECMKP_01530 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HPKECMKP_01531 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01532 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HPKECMKP_01533 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HPKECMKP_01534 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPKECMKP_01535 3.82e-188 - - - KT - - - helix_turn_helix, mercury resistance
HPKECMKP_01536 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HPKECMKP_01537 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HPKECMKP_01538 2.22e-184 - - - S - - - Peptidase_C39 like family
HPKECMKP_01539 5.37e-230 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HPKECMKP_01540 1.27e-143 - - - - - - - -
HPKECMKP_01541 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPKECMKP_01542 1.97e-110 - - - S - - - Pfam:DUF3816
HPKECMKP_01543 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HPKECMKP_01544 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01545 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HPKECMKP_01546 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_01547 4.4e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HPKECMKP_01548 2.48e-311 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HPKECMKP_01549 1.66e-61 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HPKECMKP_01550 4.97e-213 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HPKECMKP_01551 5.97e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
HPKECMKP_01552 2.53e-240 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPKECMKP_01553 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HPKECMKP_01554 2.64e-61 - - - - - - - -
HPKECMKP_01555 2.35e-106 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPKECMKP_01556 2.36e-191 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HPKECMKP_01557 3.88e-207 yjdB - - S - - - Domain of unknown function (DUF4767)
HPKECMKP_01558 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HPKECMKP_01559 2.19e-131 - - - G - - - Glycogen debranching enzyme
HPKECMKP_01560 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HPKECMKP_01561 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HPKECMKP_01562 3.37e-60 - - - S - - - MazG-like family
HPKECMKP_01563 3.83e-116 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HPKECMKP_01564 0.0 - - - M - - - MucBP domain
HPKECMKP_01565 1.42e-08 - - - - - - - -
HPKECMKP_01566 3.49e-113 - - - S - - - AAA domain
HPKECMKP_01567 2.14e-179 - - - K - - - sequence-specific DNA binding
HPKECMKP_01568 4.44e-123 - - - K - - - Helix-turn-helix domain
HPKECMKP_01569 5.36e-218 - - - K - - - Transcriptional regulator
HPKECMKP_01570 0.0 - - - C - - - FMN_bind
HPKECMKP_01572 2.39e-103 - - - K - - - Transcriptional regulator
HPKECMKP_01573 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPKECMKP_01574 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HPKECMKP_01575 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HPKECMKP_01576 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKECMKP_01577 4.42e-289 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HPKECMKP_01578 9.05e-55 - - - - - - - -
HPKECMKP_01579 1.53e-42 - - - L - - - leucine-zipper of insertion element IS481
HPKECMKP_01580 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HPKECMKP_01581 9.54e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKECMKP_01582 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HPKECMKP_01583 3.4e-178 - - - S - - - NADPH-dependent FMN reductase
HPKECMKP_01584 5.55e-244 - - - - - - - -
HPKECMKP_01585 3.28e-278 yibE - - S - - - overlaps another CDS with the same product name
HPKECMKP_01586 4.18e-163 yibF - - S - - - overlaps another CDS with the same product name
HPKECMKP_01587 3.36e-132 - - - K - - - FR47-like protein
HPKECMKP_01588 1.24e-155 gpm5 - - G - - - Phosphoglycerate mutase family
HPKECMKP_01589 1.36e-63 - - - - - - - -
HPKECMKP_01590 1.72e-245 - - - I - - - alpha/beta hydrolase fold
HPKECMKP_01591 0.0 xylP2 - - G - - - symporter
HPKECMKP_01592 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPKECMKP_01593 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HPKECMKP_01594 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HPKECMKP_01595 3.43e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HPKECMKP_01596 1.66e-154 azlC - - E - - - branched-chain amino acid
HPKECMKP_01597 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HPKECMKP_01598 1.46e-170 - - - - - - - -
HPKECMKP_01599 3.87e-152 - - - S - - - Domain of unknown function (DUF4811)
HPKECMKP_01600 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKECMKP_01601 7.79e-112 - - - K - - - MerR HTH family regulatory protein
HPKECMKP_01602 1.36e-77 - - - - - - - -
HPKECMKP_01603 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HPKECMKP_01604 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HPKECMKP_01605 4.6e-169 - - - S - - - Putative threonine/serine exporter
HPKECMKP_01606 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HPKECMKP_01607 1.55e-55 - - - - - - - -
HPKECMKP_01608 2.92e-57 - - - - - - - -
HPKECMKP_01609 1.15e-152 - - - - - - - -
HPKECMKP_01610 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HPKECMKP_01611 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_01612 8.9e-96 ywnA - - K - - - Transcriptional regulator
HPKECMKP_01613 1.16e-29 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HPKECMKP_01614 9.12e-31 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HPKECMKP_01616 1.11e-91 - - - - - - - -
HPKECMKP_01617 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HPKECMKP_01618 1.3e-203 - - - S - - - Psort location CytoplasmicMembrane, score
HPKECMKP_01619 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPKECMKP_01620 4.5e-303 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
HPKECMKP_01621 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
HPKECMKP_01622 2.6e-185 - - - - - - - -
HPKECMKP_01623 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HPKECMKP_01624 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_01625 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HPKECMKP_01626 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HPKECMKP_01627 2.21e-56 - - - - - - - -
HPKECMKP_01628 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
HPKECMKP_01629 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HPKECMKP_01630 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HPKECMKP_01631 1.78e-209 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HPKECMKP_01632 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HPKECMKP_01633 7.42e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HPKECMKP_01634 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HPKECMKP_01635 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HPKECMKP_01636 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HPKECMKP_01637 2.98e-90 - - - - - - - -
HPKECMKP_01638 4.99e-125 - - - - - - - -
HPKECMKP_01639 4.17e-67 - - - - - - - -
HPKECMKP_01640 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HPKECMKP_01641 1.21e-111 - - - - - - - -
HPKECMKP_01642 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HPKECMKP_01643 2.17e-102 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_01644 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HPKECMKP_01645 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPKECMKP_01646 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKECMKP_01648 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPKECMKP_01649 2.69e-226 - - - L ko:K07482 - ko00000 Integrase core domain
HPKECMKP_01650 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
HPKECMKP_01651 1.2e-91 - - - - - - - -
HPKECMKP_01652 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPKECMKP_01653 5.3e-202 dkgB - - S - - - reductase
HPKECMKP_01654 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HPKECMKP_01655 2.02e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HPKECMKP_01656 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HPKECMKP_01657 1.5e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HPKECMKP_01660 1.03e-156 - - - S ko:K06919 - ko00000 Virulence-associated protein E
HPKECMKP_01666 5.15e-218 - - - EG - - - EamA-like transporter family
HPKECMKP_01667 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HPKECMKP_01668 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HPKECMKP_01669 5.89e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HPKECMKP_01670 0.0 yclK - - T - - - Histidine kinase
HPKECMKP_01671 1.75e-275 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HPKECMKP_01672 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HPKECMKP_01673 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HPKECMKP_01674 2.1e-33 - - - - - - - -
HPKECMKP_01675 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01676 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKECMKP_01677 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HPKECMKP_01678 4.63e-24 - - - - - - - -
HPKECMKP_01679 2.16e-26 - - - - - - - -
HPKECMKP_01680 9.35e-24 - - - - - - - -
HPKECMKP_01681 9.35e-24 - - - - - - - -
HPKECMKP_01682 5.43e-23 - - - - - - - -
HPKECMKP_01683 8.82e-26 - - - - - - - -
HPKECMKP_01684 1.56e-22 - - - - - - - -
HPKECMKP_01685 3.26e-24 - - - - - - - -
HPKECMKP_01686 6.58e-24 - - - - - - - -
HPKECMKP_01687 0.0 inlJ - - M - - - MucBP domain
HPKECMKP_01688 0.0 - - - D - - - nuclear chromosome segregation
HPKECMKP_01689 1.27e-109 - - - K - - - MarR family
HPKECMKP_01690 9.28e-58 - - - - - - - -
HPKECMKP_01691 1.28e-51 - - - - - - - -
HPKECMKP_01692 2.54e-289 - - - L - - - Belongs to the 'phage' integrase family
HPKECMKP_01693 1.1e-06 - - - K ko:K07727 - ko00000,ko03000 transcriptional regulator
HPKECMKP_01695 3.96e-13 - - - - - - - -
HPKECMKP_01697 3.18e-41 - - - - - - - -
HPKECMKP_01698 9.72e-184 - - - L - - - DNA replication protein
HPKECMKP_01699 0.0 - - - S - - - Virulence-associated protein E
HPKECMKP_01700 3.36e-96 - - - - - - - -
HPKECMKP_01702 7.63e-65 - - - S - - - Head-tail joining protein
HPKECMKP_01703 2.59e-89 - - - L - - - HNH endonuclease
HPKECMKP_01704 4.3e-106 - - - L - - - overlaps another CDS with the same product name
HPKECMKP_01705 0.0 terL - - S - - - overlaps another CDS with the same product name
HPKECMKP_01706 0.000495 - - - - - - - -
HPKECMKP_01707 3.18e-262 - - - S - - - Phage portal protein
HPKECMKP_01708 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HPKECMKP_01709 8.32e-56 - - - S - - - Phage gp6-like head-tail connector protein
HPKECMKP_01710 4.88e-79 - - - - - - - -
HPKECMKP_01713 1.98e-40 - - - - - - - -
HPKECMKP_01715 2.12e-275 int3 - - L - - - Belongs to the 'phage' integrase family
HPKECMKP_01716 1.58e-98 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 DNA mismatch endonuclease Vsr
HPKECMKP_01717 7.39e-15 - - - S - - - AAA ATPase domain
HPKECMKP_01718 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HPKECMKP_01719 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
HPKECMKP_01720 2.55e-65 - - - - - - - -
HPKECMKP_01721 7.21e-35 - - - - - - - -
HPKECMKP_01722 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HPKECMKP_01723 8.43e-97 - - - S - - - COG NOG18757 non supervised orthologous group
HPKECMKP_01724 2.47e-53 - - - - - - - -
HPKECMKP_01725 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HPKECMKP_01726 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HPKECMKP_01727 2.53e-242 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HPKECMKP_01728 1.47e-144 - - - S - - - VIT family
HPKECMKP_01729 2.66e-155 - - - S - - - membrane
HPKECMKP_01730 1.63e-203 - - - EG - - - EamA-like transporter family
HPKECMKP_01731 7.23e-107 - - - S ko:K02348 - ko00000 GNAT family
HPKECMKP_01732 3.57e-150 - - - GM - - - NmrA-like family
HPKECMKP_01733 4.79e-21 - - - - - - - -
HPKECMKP_01734 4.59e-74 - - - - - - - -
HPKECMKP_01735 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HPKECMKP_01736 9.16e-111 - - - - - - - -
HPKECMKP_01737 2.11e-82 - - - - - - - -
HPKECMKP_01738 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HPKECMKP_01739 1.7e-70 - - - - - - - -
HPKECMKP_01740 9.91e-87 yeaO - - S - - - Protein of unknown function, DUF488
HPKECMKP_01741 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HPKECMKP_01742 2.71e-89 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HPKECMKP_01743 1.93e-209 - - - GM - - - NmrA-like family
HPKECMKP_01744 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HPKECMKP_01745 7.59e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_01746 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKECMKP_01747 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HPKECMKP_01748 2.7e-30 - - - S - - - Belongs to the LOG family
HPKECMKP_01749 1.01e-255 glmS2 - - M - - - SIS domain
HPKECMKP_01750 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPKECMKP_01751 2.24e-283 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HPKECMKP_01752 2.54e-159 - - - S - - - YjbR
HPKECMKP_01754 0.0 cadA - - P - - - P-type ATPase
HPKECMKP_01755 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HPKECMKP_01756 1.52e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HPKECMKP_01757 4.29e-101 - - - - - - - -
HPKECMKP_01758 8.46e-50 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HPKECMKP_01759 3.44e-127 - - - FG - - - HIT domain
HPKECMKP_01760 4.27e-223 ydhF - - S - - - Aldo keto reductase
HPKECMKP_01761 8.93e-71 - - - S - - - Pfam:DUF59
HPKECMKP_01762 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPKECMKP_01763 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HPKECMKP_01764 1.87e-249 - - - V - - - Beta-lactamase
HPKECMKP_01765 1.07e-124 - - - V - - - VanZ like family
HPKECMKP_01766 9.02e-70 - - - - - - - -
HPKECMKP_01767 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
HPKECMKP_01768 1.95e-41 - - - - - - - -
HPKECMKP_01769 1.35e-34 - - - - - - - -
HPKECMKP_01770 6.87e-131 - - - K - - - DNA-templated transcription, initiation
HPKECMKP_01771 1.9e-168 - - - - - - - -
HPKECMKP_01772 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HPKECMKP_01773 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HPKECMKP_01774 1.94e-170 lytE - - M - - - NlpC/P60 family
HPKECMKP_01775 8.01e-64 - - - K - - - sequence-specific DNA binding
HPKECMKP_01776 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HPKECMKP_01777 1.72e-214 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKECMKP_01778 1.13e-257 yueF - - S - - - AI-2E family transporter
HPKECMKP_01779 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HPKECMKP_01780 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HPKECMKP_01781 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HPKECMKP_01782 1e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HPKECMKP_01783 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HPKECMKP_01784 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPKECMKP_01785 0.0 - - - - - - - -
HPKECMKP_01786 2.12e-252 - - - M - - - MucBP domain
HPKECMKP_01787 7.84e-208 lysR5 - - K - - - LysR substrate binding domain
HPKECMKP_01788 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HPKECMKP_01789 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HPKECMKP_01790 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HPKECMKP_01791 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPKECMKP_01792 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPKECMKP_01793 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPKECMKP_01794 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HPKECMKP_01795 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HPKECMKP_01796 2.5e-132 - - - L - - - Integrase
HPKECMKP_01797 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HPKECMKP_01798 5.6e-41 - - - - - - - -
HPKECMKP_01799 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HPKECMKP_01800 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPKECMKP_01801 3.32e-284 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HPKECMKP_01802 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HPKECMKP_01803 1.03e-239 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPKECMKP_01804 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HPKECMKP_01805 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKECMKP_01806 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HPKECMKP_01807 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPKECMKP_01808 5.48e-90 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HPKECMKP_01809 3.98e-151 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_01810 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPKECMKP_01811 1.97e-111 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKECMKP_01812 2.88e-237 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKECMKP_01813 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HPKECMKP_01814 1.29e-206 - - - K - - - LysR substrate binding domain
HPKECMKP_01815 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKECMKP_01816 0.0 - - - S - - - MucBP domain
HPKECMKP_01818 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HPKECMKP_01819 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
HPKECMKP_01820 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_01821 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_01822 5.97e-85 - - - - - - - -
HPKECMKP_01823 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HPKECMKP_01824 7.06e-31 - - - K - - - Transcriptional regulator
HPKECMKP_01825 2.08e-85 - - - S - - - Protein of unknown function (DUF1093)
HPKECMKP_01826 3.05e-281 - - - S - - - Membrane
HPKECMKP_01827 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
HPKECMKP_01828 1.31e-139 yoaZ - - S - - - intracellular protease amidase
HPKECMKP_01829 1.4e-57 - - - K - - - HxlR-like helix-turn-helix
HPKECMKP_01830 8.95e-53 - - - C - - - Alcohol dehydrogenase GroES-like domain
HPKECMKP_01831 1.68e-121 - - - C - - - Alcohol dehydrogenase GroES-like domain
HPKECMKP_01832 1.83e-259 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HPKECMKP_01833 6.27e-104 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPKECMKP_01834 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPKECMKP_01835 7.75e-153 yciB - - M - - - ErfK YbiS YcfS YnhG
HPKECMKP_01837 8.91e-51 - - - - - - - -
HPKECMKP_01838 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPKECMKP_01839 9.26e-233 ydbI - - K - - - AI-2E family transporter
HPKECMKP_01840 1.54e-269 xylR - - GK - - - ROK family
HPKECMKP_01841 1.28e-56 - - - - - - - -
HPKECMKP_01842 9.51e-135 - - - - - - - -
HPKECMKP_01843 3.1e-214 icaA - - M - - - Glycosyl transferase family group 2
HPKECMKP_01844 4.61e-87 icaA - - M - - - Glycosyl transferase family group 2
HPKECMKP_01845 0.0 - - - - - - - -
HPKECMKP_01846 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HPKECMKP_01847 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HPKECMKP_01848 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HPKECMKP_01849 9.66e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HPKECMKP_01850 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPKECMKP_01851 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HPKECMKP_01852 5.47e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HPKECMKP_01853 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HPKECMKP_01854 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HPKECMKP_01855 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HPKECMKP_01856 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HPKECMKP_01857 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPKECMKP_01858 8.25e-113 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_01859 3.12e-131 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_01860 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPKECMKP_01861 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPKECMKP_01862 2.2e-199 - - - S - - - Tetratricopeptide repeat
HPKECMKP_01863 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPKECMKP_01864 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPKECMKP_01865 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPKECMKP_01866 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HPKECMKP_01867 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HPKECMKP_01868 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HPKECMKP_01869 5.12e-31 - - - - - - - -
HPKECMKP_01870 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HPKECMKP_01871 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01872 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPKECMKP_01873 8.45e-162 epsB - - M - - - biosynthesis protein
HPKECMKP_01874 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
HPKECMKP_01875 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HPKECMKP_01876 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HPKECMKP_01877 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
HPKECMKP_01878 1.15e-258 cps4F - - M - - - Glycosyl transferases group 1
HPKECMKP_01879 1.94e-244 cps4G - - M - - - Glycosyltransferase Family 4
HPKECMKP_01880 1.91e-297 - - - - - - - -
HPKECMKP_01881 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
HPKECMKP_01882 0.0 cps4J - - S - - - MatE
HPKECMKP_01883 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HPKECMKP_01884 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HPKECMKP_01885 8.57e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPKECMKP_01886 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HPKECMKP_01887 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPKECMKP_01888 6.62e-62 - - - - - - - -
HPKECMKP_01889 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPKECMKP_01890 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKECMKP_01891 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HPKECMKP_01892 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HPKECMKP_01893 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPKECMKP_01894 1.25e-129 - - - K - - - Helix-turn-helix domain
HPKECMKP_01895 1.3e-266 - - - EGP - - - Major facilitator Superfamily
HPKECMKP_01896 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HPKECMKP_01897 1.02e-183 - - - Q - - - Methyltransferase
HPKECMKP_01898 1.75e-43 - - - - - - - -
HPKECMKP_01900 2.78e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HPKECMKP_01901 1.46e-135 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_01902 1.19e-270 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_01903 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_01904 4.46e-281 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HPKECMKP_01905 6.27e-131 - - - L - - - Helix-turn-helix domain
HPKECMKP_01906 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HPKECMKP_01907 3.81e-87 - - - - - - - -
HPKECMKP_01908 1.01e-100 - - - - - - - -
HPKECMKP_01909 5.44e-277 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HPKECMKP_01910 3.7e-121 - - - - - - - -
HPKECMKP_01911 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPKECMKP_01912 7.68e-48 ynzC - - S - - - UPF0291 protein
HPKECMKP_01913 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HPKECMKP_01914 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HPKECMKP_01915 2.11e-171 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HPKECMKP_01916 5.67e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HPKECMKP_01917 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKECMKP_01918 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HPKECMKP_01919 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HPKECMKP_01920 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPKECMKP_01921 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HPKECMKP_01922 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPKECMKP_01923 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPKECMKP_01924 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HPKECMKP_01925 1.89e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HPKECMKP_01926 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPKECMKP_01927 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPKECMKP_01928 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HPKECMKP_01929 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HPKECMKP_01930 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HPKECMKP_01931 3.28e-63 ylxQ - - J - - - ribosomal protein
HPKECMKP_01932 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPKECMKP_01933 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPKECMKP_01934 0.0 - - - G - - - Major Facilitator
HPKECMKP_01935 3.52e-273 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPKECMKP_01936 1.63e-121 - - - - - - - -
HPKECMKP_01937 8.18e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPKECMKP_01938 2.84e-244 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HPKECMKP_01939 2.31e-111 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPKECMKP_01940 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPKECMKP_01941 9.2e-243 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HPKECMKP_01942 2.06e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HPKECMKP_01943 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPKECMKP_01944 4.72e-113 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPKECMKP_01945 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HPKECMKP_01946 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPKECMKP_01947 1.26e-267 pbpX2 - - V - - - Beta-lactamase
HPKECMKP_01948 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HPKECMKP_01949 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPKECMKP_01950 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HPKECMKP_01951 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPKECMKP_01952 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPKECMKP_01953 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPKECMKP_01954 3.51e-19 - - - M - - - Host cell surface-exposed lipoprotein
HPKECMKP_01955 2.02e-66 - - - - - - - -
HPKECMKP_01956 4.78e-65 - - - - - - - -
HPKECMKP_01957 1.35e-148 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HPKECMKP_01958 1.38e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HPKECMKP_01959 7.36e-171 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPKECMKP_01960 1.49e-75 - - - - - - - -
HPKECMKP_01961 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPKECMKP_01962 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPKECMKP_01963 6.97e-150 yjcF - - J - - - HAD-hyrolase-like
HPKECMKP_01964 4.4e-212 - - - G - - - Fructosamine kinase
HPKECMKP_01965 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HPKECMKP_01966 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HPKECMKP_01967 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPKECMKP_01968 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPKECMKP_01969 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPKECMKP_01970 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPKECMKP_01971 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPKECMKP_01972 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HPKECMKP_01973 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPKECMKP_01974 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HPKECMKP_01975 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HPKECMKP_01976 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HPKECMKP_01977 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPKECMKP_01978 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HPKECMKP_01979 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPKECMKP_01980 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HPKECMKP_01981 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HPKECMKP_01982 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HPKECMKP_01983 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPKECMKP_01984 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPKECMKP_01985 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HPKECMKP_01986 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01987 1.44e-253 - - - - - - - -
HPKECMKP_01988 6.08e-253 - - - - - - - -
HPKECMKP_01989 4.08e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HPKECMKP_01990 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_01991 0.000238 - - - S - - - Protein of unknown function (DUF2992)
HPKECMKP_01992 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
HPKECMKP_01993 5.9e-103 - - - K - - - MarR family
HPKECMKP_01994 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HPKECMKP_01996 1.63e-201 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_01997 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HPKECMKP_01998 3.86e-261 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKECMKP_01999 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HPKECMKP_02000 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPKECMKP_02002 4.61e-222 cryZ - - C - - - nadph quinone reductase
HPKECMKP_02003 2.33e-206 - - - K - - - Transcriptional regulator
HPKECMKP_02004 8.62e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HPKECMKP_02005 4.15e-145 - - - GM - - - NmrA-like family
HPKECMKP_02006 2.63e-206 - - - S - - - Alpha beta hydrolase
HPKECMKP_02007 2.13e-168 - - - K - - - Helix-turn-helix domain, rpiR family
HPKECMKP_02008 4.67e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HPKECMKP_02009 3.72e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HPKECMKP_02010 6.03e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_02011 3.42e-12 - - - S - - - protein with an alpha beta hydrolase fold
HPKECMKP_02012 1.93e-35 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_02013 1.55e-07 - - - K - - - transcriptional regulator
HPKECMKP_02014 1.12e-273 - - - S - - - membrane
HPKECMKP_02015 3.54e-104 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_02016 0.0 - - - S - - - Zinc finger, swim domain protein
HPKECMKP_02017 4.88e-147 - - - GM - - - epimerase
HPKECMKP_02018 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
HPKECMKP_02019 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
HPKECMKP_02020 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HPKECMKP_02021 4.83e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HPKECMKP_02022 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPKECMKP_02023 6.03e-270 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HPKECMKP_02024 4.38e-102 - - - K - - - Transcriptional regulator
HPKECMKP_02025 6.53e-307 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HPKECMKP_02026 7.36e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPKECMKP_02027 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HPKECMKP_02028 3.55e-231 - - - C - - - Zinc-binding dehydrogenase
HPKECMKP_02029 1.49e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HPKECMKP_02030 2.02e-268 - - - - - - - -
HPKECMKP_02031 4.3e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_02032 2.48e-51 - - - P - - - Rhodanese Homology Domain
HPKECMKP_02033 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HPKECMKP_02034 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_02035 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_02036 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HPKECMKP_02037 5.84e-294 - - - M - - - O-Antigen ligase
HPKECMKP_02038 6.85e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HPKECMKP_02039 6.55e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPKECMKP_02040 2.6e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HPKECMKP_02041 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPKECMKP_02043 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
HPKECMKP_02044 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HPKECMKP_02045 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPKECMKP_02046 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HPKECMKP_02047 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HPKECMKP_02048 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_02049 5.16e-248 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HPKECMKP_02050 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
HPKECMKP_02051 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKECMKP_02052 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPKECMKP_02053 2.2e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HPKECMKP_02054 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPKECMKP_02055 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
HPKECMKP_02056 1.15e-281 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_02057 1.02e-203 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPKECMKP_02058 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPKECMKP_02059 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HPKECMKP_02060 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
HPKECMKP_02061 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
HPKECMKP_02062 6.17e-260 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_02063 4.22e-83 - - - - - - - -
HPKECMKP_02064 7.54e-200 estA - - S - - - Putative esterase
HPKECMKP_02065 5.44e-174 - - - K - - - UTRA domain
HPKECMKP_02066 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_02067 3.98e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPKECMKP_02068 1.69e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HPKECMKP_02069 2.64e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HPKECMKP_02070 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_02071 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_02072 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HPKECMKP_02073 1.09e-232 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPKECMKP_02074 7.04e-144 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPKECMKP_02075 1.84e-283 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HPKECMKP_02076 7.66e-137 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPKECMKP_02077 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HPKECMKP_02078 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HPKECMKP_02079 5.74e-32 - - - - - - - -
HPKECMKP_02080 1.95e-116 - - - - - - - -
HPKECMKP_02081 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HPKECMKP_02082 0.0 XK27_09800 - - I - - - Acyltransferase family
HPKECMKP_02083 2.09e-60 - - - S - - - MORN repeat
HPKECMKP_02084 6.35e-69 - - - - - - - -
HPKECMKP_02085 5.53e-205 - - - S - - - Domain of unknown function (DUF4767)
HPKECMKP_02086 1.43e-66 - - - - - - - -
HPKECMKP_02087 9.62e-12 - - - - - - - -
HPKECMKP_02088 2.36e-121 - - - D - - - nuclear chromosome segregation
HPKECMKP_02089 1.59e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPKECMKP_02090 9.71e-231 - - - S - - - Cysteine-rich secretory protein family
HPKECMKP_02091 6e-39 - - - S - - - Cysteine-rich secretory protein family
HPKECMKP_02092 8.2e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_02093 0.0 - - - L - - - AAA domain
HPKECMKP_02094 1.37e-83 - - - K - - - Helix-turn-helix domain
HPKECMKP_02095 3.03e-190 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HPKECMKP_02096 2.97e-69 - - - - - - - -
HPKECMKP_02097 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HPKECMKP_02098 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HPKECMKP_02099 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HPKECMKP_02100 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HPKECMKP_02101 1.05e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HPKECMKP_02102 7.98e-80 - - - M - - - Lysin motif
HPKECMKP_02103 2.75e-156 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_02104 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_02105 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPKECMKP_02106 7.93e-290 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HPKECMKP_02107 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HPKECMKP_02108 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HPKECMKP_02109 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HPKECMKP_02110 1.17e-135 - - - K - - - transcriptional regulator
HPKECMKP_02111 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HPKECMKP_02112 1.49e-63 - - - - - - - -
HPKECMKP_02113 2.26e-179 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HPKECMKP_02114 4.16e-108 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HPKECMKP_02115 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HPKECMKP_02116 2.87e-56 - - - - - - - -
HPKECMKP_02117 3.35e-75 - - - - - - - -
HPKECMKP_02118 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKECMKP_02119 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
HPKECMKP_02120 2.42e-65 - - - - - - - -
HPKECMKP_02121 1.33e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HPKECMKP_02122 1.39e-194 hpk2 - - T - - - Histidine kinase
HPKECMKP_02123 6.56e-90 hpk2 - - T - - - Histidine kinase
HPKECMKP_02124 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
HPKECMKP_02125 2.94e-297 ydiC - - EGP - - - Major Facilitator
HPKECMKP_02126 2.15e-206 - - - K ko:K02538 - ko00000,ko03000 PRD domain
HPKECMKP_02127 1.32e-240 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HPKECMKP_02128 1.69e-295 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HPKECMKP_02129 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HPKECMKP_02130 3.53e-100 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPKECMKP_02131 6.69e-149 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HPKECMKP_02132 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HPKECMKP_02133 1.85e-61 icaB - - G ko:K21478 - ko00000,ko01000 Polysaccharide deacetylase
HPKECMKP_02135 2.69e-163 icaA - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyltransferases, probably involved in cell wall biogenesis
HPKECMKP_02136 8.94e-152 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPKECMKP_02137 4.6e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HPKECMKP_02138 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HPKECMKP_02139 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
HPKECMKP_02140 1.06e-16 - - - - - - - -
HPKECMKP_02141 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HPKECMKP_02142 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HPKECMKP_02143 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HPKECMKP_02144 8.66e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HPKECMKP_02145 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HPKECMKP_02146 9.62e-19 - - - - - - - -
HPKECMKP_02147 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HPKECMKP_02148 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HPKECMKP_02149 0.0 mdr - - EGP - - - Major Facilitator
HPKECMKP_02150 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPKECMKP_02151 1.93e-156 - - - - - - - -
HPKECMKP_02152 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKECMKP_02153 3.91e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HPKECMKP_02154 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HPKECMKP_02155 1.52e-241 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HPKECMKP_02156 1.61e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HPKECMKP_02157 2.2e-141 - - - GK - - - ROK family
HPKECMKP_02158 5.91e-208 - - - P - - - Major Facilitator Superfamily
HPKECMKP_02159 6.6e-183 lipA - - I - - - Carboxylesterase family
HPKECMKP_02160 8.71e-145 - - - K - - - helix_turn_helix, arabinose operon control protein
HPKECMKP_02161 1.03e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HPKECMKP_02162 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HPKECMKP_02163 2.07e-123 - - - - - - - -
HPKECMKP_02164 7.75e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HPKECMKP_02165 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HPKECMKP_02176 5.16e-208 - - - K - - - helix_turn_helix, arabinose operon control protein
HPKECMKP_02177 6.22e-140 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HPKECMKP_02178 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HPKECMKP_02179 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HPKECMKP_02180 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HPKECMKP_02181 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HPKECMKP_02182 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPKECMKP_02183 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HPKECMKP_02184 9.11e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HPKECMKP_02185 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HPKECMKP_02186 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HPKECMKP_02187 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HPKECMKP_02188 4.09e-89 - - - - - - - -
HPKECMKP_02189 2.4e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HPKECMKP_02190 9.89e-74 ytpP - - CO - - - Thioredoxin
HPKECMKP_02191 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPKECMKP_02192 3.89e-62 - - - - - - - -
HPKECMKP_02193 1.47e-69 - - - - - - - -
HPKECMKP_02194 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
HPKECMKP_02195 4.05e-98 - - - - - - - -
HPKECMKP_02196 4.15e-78 - - - - - - - -
HPKECMKP_02197 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HPKECMKP_02198 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HPKECMKP_02200 7.38e-78 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HPKECMKP_02202 6.73e-133 - - - L - - - Phage integrase, N-terminal SAM-like domain
HPKECMKP_02203 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
HPKECMKP_02204 1.31e-64 - - - - - - - -
HPKECMKP_02205 9.26e-226 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HPKECMKP_02206 8.05e-178 - - - F - - - NUDIX domain
HPKECMKP_02207 2.68e-32 - - - - - - - -
HPKECMKP_02209 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_02210 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HPKECMKP_02211 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HPKECMKP_02212 2.29e-48 - - - - - - - -
HPKECMKP_02213 1.11e-45 - - - - - - - -
HPKECMKP_02214 2.81e-278 - - - T - - - diguanylate cyclase
HPKECMKP_02215 1.69e-102 - - - L - - - Integrase
HPKECMKP_02216 3.75e-279 - - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
HPKECMKP_02217 6.58e-160 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HPKECMKP_02218 2.05e-37 - - - - - - - -
HPKECMKP_02219 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HPKECMKP_02220 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
HPKECMKP_02221 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HPKECMKP_02222 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPKECMKP_02223 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPKECMKP_02224 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPKECMKP_02225 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HPKECMKP_02226 7.01e-30 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPKECMKP_02227 1.51e-78 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPKECMKP_02228 5.61e-251 - - - S - - - Helix-turn-helix domain
HPKECMKP_02229 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HPKECMKP_02230 1.25e-39 - - - M - - - Lysin motif
HPKECMKP_02231 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HPKECMKP_02232 3.28e-280 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HPKECMKP_02233 1.69e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HPKECMKP_02234 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPKECMKP_02235 2.08e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HPKECMKP_02236 9.1e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HPKECMKP_02237 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPKECMKP_02238 5.18e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPKECMKP_02239 6.46e-109 - - - - - - - -
HPKECMKP_02240 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_02241 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPKECMKP_02242 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPKECMKP_02243 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HPKECMKP_02244 1.14e-206 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HPKECMKP_02245 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HPKECMKP_02246 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HPKECMKP_02247 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HPKECMKP_02248 0.0 qacA - - EGP - - - Major Facilitator
HPKECMKP_02249 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
HPKECMKP_02250 2.38e-158 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HPKECMKP_02251 6.08e-91 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HPKECMKP_02252 3.49e-219 cpsY - - K - - - Transcriptional regulator, LysR family
HPKECMKP_02253 5.13e-292 XK27_05470 - - E - - - Methionine synthase
HPKECMKP_02254 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPKECMKP_02255 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPKECMKP_02256 1.1e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HPKECMKP_02257 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPKECMKP_02258 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPKECMKP_02259 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HPKECMKP_02260 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPKECMKP_02261 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPKECMKP_02262 1.04e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HPKECMKP_02263 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPKECMKP_02264 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPKECMKP_02265 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPKECMKP_02266 2.21e-227 - - - K - - - Transcriptional regulator
HPKECMKP_02267 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HPKECMKP_02268 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HPKECMKP_02269 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPKECMKP_02270 1.07e-43 - - - S - - - YozE SAM-like fold
HPKECMKP_02271 2.2e-223 - - - L - - - Initiator Replication protein
HPKECMKP_02272 1.02e-109 - - - - - - - -
HPKECMKP_02273 2.17e-15 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HPKECMKP_02274 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HPKECMKP_02275 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HPKECMKP_02276 1.16e-79 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HPKECMKP_02277 4.9e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPKECMKP_02278 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
HPKECMKP_02279 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HPKECMKP_02280 3.62e-137 - - - L - - - Integrase
HPKECMKP_02281 8.03e-34 - - - - - - - -
HPKECMKP_02282 9.8e-200 - - - L - - - Initiator Replication protein
HPKECMKP_02283 2.9e-73 - - - - - - - -
HPKECMKP_02284 9.18e-12 ysnF - - S - - - Heat induced stress protein YflT
HPKECMKP_02285 1.72e-18 - - - S - - - Class II bacteriocin
HPKECMKP_02287 3.21e-50 - - - - - - - -
HPKECMKP_02288 2.11e-144 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPKECMKP_02289 3.39e-26 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPKECMKP_02290 6.25e-181 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPKECMKP_02291 9.49e-42 - - - L - - - Initiator Replication protein
HPKECMKP_02292 1.1e-51 - - - L - - - Initiator Replication protein
HPKECMKP_02293 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPKECMKP_02294 2.13e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HPKECMKP_02295 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPKECMKP_02296 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HPKECMKP_02297 4.19e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
HPKECMKP_02298 4.49e-315 - - - M - - - Glycosyl transferase family group 2
HPKECMKP_02299 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPKECMKP_02300 2.99e-129 - - - S - - - Plasmid replication protein
HPKECMKP_02304 0.0 - - - S - - - ABC transporter, ATP-binding protein
HPKECMKP_02305 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HPKECMKP_02307 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPKECMKP_02308 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HPKECMKP_02310 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HPKECMKP_02311 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKECMKP_02312 1.07e-203 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HPKECMKP_02313 1.19e-226 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HPKECMKP_02314 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HPKECMKP_02315 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
HPKECMKP_02316 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
HPKECMKP_02317 1.61e-36 - - - - - - - -
HPKECMKP_02318 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HPKECMKP_02319 4.6e-102 rppH3 - - F - - - NUDIX domain
HPKECMKP_02320 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPKECMKP_02321 2.11e-127 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_02322 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HPKECMKP_02323 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
HPKECMKP_02324 1.03e-91 - - - K - - - MarR family
HPKECMKP_02325 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
HPKECMKP_02326 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_02327 1.5e-315 steT - - E ko:K03294 - ko00000 amino acid
HPKECMKP_02328 1.57e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HPKECMKP_02329 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HPKECMKP_02330 1.34e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HPKECMKP_02331 2.99e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPKECMKP_02332 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_02333 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_02334 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HPKECMKP_02335 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_02337 1.28e-54 - - - - - - - -
HPKECMKP_02338 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKECMKP_02339 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKECMKP_02340 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HPKECMKP_02341 1.01e-188 - - - - - - - -
HPKECMKP_02342 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HPKECMKP_02343 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HPKECMKP_02344 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HPKECMKP_02345 1.48e-27 - - - - - - - -
HPKECMKP_02346 7.48e-96 - - - F - - - Nudix hydrolase
HPKECMKP_02347 3.03e-190 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HPKECMKP_02348 6.12e-115 - - - - - - - -
HPKECMKP_02349 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HPKECMKP_02350 1.09e-60 - - - - - - - -
HPKECMKP_02351 1.89e-90 - - - O - - - OsmC-like protein
HPKECMKP_02352 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPKECMKP_02353 0.0 oatA - - I - - - Acyltransferase
HPKECMKP_02354 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPKECMKP_02355 7.44e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HPKECMKP_02356 8.95e-96 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HPKECMKP_02357 1.11e-290 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HPKECMKP_02358 2.71e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HPKECMKP_02359 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HPKECMKP_02360 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HPKECMKP_02361 1.36e-27 - - - - - - - -
HPKECMKP_02362 6.16e-107 - - - K - - - Transcriptional regulator
HPKECMKP_02363 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HPKECMKP_02364 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKECMKP_02365 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPKECMKP_02366 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKECMKP_02367 1.06e-314 - - - EGP - - - Major Facilitator
HPKECMKP_02368 2.08e-117 - - - V - - - VanZ like family
HPKECMKP_02369 3.88e-46 - - - - - - - -
HPKECMKP_02370 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HPKECMKP_02372 6.37e-186 - - - - - - - -
HPKECMKP_02373 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPKECMKP_02374 3.51e-197 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HPKECMKP_02375 1.17e-167 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HPKECMKP_02376 2.49e-95 - - - - - - - -
HPKECMKP_02377 3.38e-70 - - - - - - - -
HPKECMKP_02378 3.43e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HPKECMKP_02379 4.22e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HPKECMKP_02380 3.14e-187 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HPKECMKP_02381 5.44e-159 - - - T - - - EAL domain
HPKECMKP_02382 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPKECMKP_02383 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPKECMKP_02384 2.18e-182 ybbR - - S - - - YbbR-like protein
HPKECMKP_02385 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPKECMKP_02386 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
HPKECMKP_02387 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_02388 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKECMKP_02389 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HPKECMKP_02390 8.14e-209 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HPKECMKP_02391 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HPKECMKP_02392 1.98e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HPKECMKP_02393 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HPKECMKP_02394 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HPKECMKP_02395 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HPKECMKP_02396 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPKECMKP_02397 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKECMKP_02398 5.62e-137 - - - - - - - -
HPKECMKP_02399 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_02400 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKECMKP_02401 0.0 - - - M - - - Domain of unknown function (DUF5011)
HPKECMKP_02402 1.05e-254 - - - M - - - Domain of unknown function (DUF5011)
HPKECMKP_02403 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPKECMKP_02404 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPKECMKP_02405 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HPKECMKP_02406 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HPKECMKP_02407 0.0 eriC - - P ko:K03281 - ko00000 chloride
HPKECMKP_02408 2.42e-169 - - - - - - - -
HPKECMKP_02409 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPKECMKP_02410 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPKECMKP_02411 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HPKECMKP_02412 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPKECMKP_02413 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HPKECMKP_02414 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HPKECMKP_02416 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPKECMKP_02417 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKECMKP_02418 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HPKECMKP_02419 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HPKECMKP_02420 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HPKECMKP_02421 2.83e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HPKECMKP_02422 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
HPKECMKP_02423 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HPKECMKP_02424 7.49e-300 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPKECMKP_02425 2.59e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPKECMKP_02426 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPKECMKP_02427 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPKECMKP_02428 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HPKECMKP_02429 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HPKECMKP_02430 7.69e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPKECMKP_02431 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPKECMKP_02432 2.4e-169 - - - T - - - Putative diguanylate phosphodiesterase
HPKECMKP_02433 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPKECMKP_02434 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HPKECMKP_02435 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HPKECMKP_02436 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPKECMKP_02437 0.0 nox - - C - - - NADH oxidase
HPKECMKP_02438 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
HPKECMKP_02439 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HPKECMKP_02440 1.98e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HPKECMKP_02441 6.26e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPKECMKP_02442 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPKECMKP_02443 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HPKECMKP_02444 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HPKECMKP_02445 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HPKECMKP_02446 2.69e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPKECMKP_02447 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPKECMKP_02448 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HPKECMKP_02449 4.48e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HPKECMKP_02450 5.67e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HPKECMKP_02451 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKECMKP_02452 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HPKECMKP_02453 4.29e-275 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HPKECMKP_02454 3.41e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPKECMKP_02455 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPKECMKP_02456 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPKECMKP_02457 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HPKECMKP_02458 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HPKECMKP_02459 2.14e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HPKECMKP_02460 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HPKECMKP_02461 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HPKECMKP_02462 0.0 ydaO - - E - - - amino acid
HPKECMKP_02463 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPKECMKP_02464 5.69e-54 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPKECMKP_02465 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKECMKP_02466 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPKECMKP_02467 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HPKECMKP_02468 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPKECMKP_02469 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPKECMKP_02470 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HPKECMKP_02471 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HPKECMKP_02472 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HPKECMKP_02473 2.68e-176 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPKECMKP_02474 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HPKECMKP_02475 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_02476 2.8e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HPKECMKP_02477 5.35e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HPKECMKP_02478 4.06e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HPKECMKP_02479 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HPKECMKP_02480 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPKECMKP_02481 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HPKECMKP_02482 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HPKECMKP_02483 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HPKECMKP_02484 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPKECMKP_02485 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HPKECMKP_02486 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPKECMKP_02487 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPKECMKP_02488 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPKECMKP_02489 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPKECMKP_02490 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HPKECMKP_02491 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HPKECMKP_02492 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPKECMKP_02493 1.43e-252 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPKECMKP_02494 2.77e-139 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HPKECMKP_02495 5.03e-50 - - - K - - - Helix-turn-helix domain
HPKECMKP_02496 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPKECMKP_02497 2.26e-84 - - - L - - - nuclease
HPKECMKP_02498 2.38e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HPKECMKP_02499 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPKECMKP_02500 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPKECMKP_02501 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPKECMKP_02502 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPKECMKP_02503 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKECMKP_02504 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HPKECMKP_02505 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPKECMKP_02506 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HPKECMKP_02507 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HPKECMKP_02508 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HPKECMKP_02509 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPKECMKP_02510 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPKECMKP_02511 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKECMKP_02512 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPKECMKP_02513 4.91e-265 yacL - - S - - - domain protein
HPKECMKP_02514 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPKECMKP_02515 1.6e-163 - - - L - - - Replication protein
HPKECMKP_02517 1.59e-225 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKECMKP_02518 4.05e-211 - - - L - - - PFAM Integrase catalytic region
HPKECMKP_02519 1.95e-114 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HPKECMKP_02520 8.3e-87 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HPKECMKP_02521 2.45e-177 - - - L - - - PFAM Integrase catalytic region
HPKECMKP_02522 2.37e-250 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKECMKP_02523 1.2e-200 is18 - - L - - - Integrase core domain
HPKECMKP_02524 2.39e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKECMKP_02525 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HPKECMKP_02526 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HPKECMKP_02527 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPKECMKP_02528 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HPKECMKP_02529 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
HPKECMKP_02530 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPKECMKP_02531 7.04e-226 - - - EG - - - EamA-like transporter family
HPKECMKP_02532 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HPKECMKP_02533 1.88e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HPKECMKP_02534 1.18e-175 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HPKECMKP_02535 1.49e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPKECMKP_02536 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HPKECMKP_02537 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HPKECMKP_02538 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPKECMKP_02539 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HPKECMKP_02540 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HPKECMKP_02541 0.0 levR - - K - - - Sigma-54 interaction domain
HPKECMKP_02542 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
HPKECMKP_02543 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HPKECMKP_02544 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HPKECMKP_02545 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HPKECMKP_02546 1e-200 - - - G - - - Peptidase_C39 like family
HPKECMKP_02548 1.19e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPKECMKP_02549 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HPKECMKP_02550 3.76e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HPKECMKP_02551 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HPKECMKP_02552 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HPKECMKP_02553 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HPKECMKP_02554 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPKECMKP_02555 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPKECMKP_02556 1.14e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPKECMKP_02557 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HPKECMKP_02558 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPKECMKP_02559 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPKECMKP_02560 4.33e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HPKECMKP_02561 5.32e-246 ysdE - - P - - - Citrate transporter
HPKECMKP_02562 5.35e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HPKECMKP_02563 1.38e-71 - - - S - - - Cupin domain
HPKECMKP_02564 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
HPKECMKP_02568 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
HPKECMKP_02569 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HPKECMKP_02571 3.54e-59 - - - - - - - -
HPKECMKP_02572 7.55e-136 - - - S - - - Psort location Cytoplasmic, score 8.96
HPKECMKP_02573 1.05e-118 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKECMKP_02575 3.3e-126 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HPKECMKP_02576 3.13e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HPKECMKP_02577 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HPKECMKP_02578 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPKECMKP_02579 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HPKECMKP_02580 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPKECMKP_02581 6.65e-180 yqeM - - Q - - - Methyltransferase
HPKECMKP_02582 3.04e-280 ylbM - - S - - - Belongs to the UPF0348 family
HPKECMKP_02583 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HPKECMKP_02584 1.77e-123 - - - S - - - Peptidase propeptide and YPEB domain
HPKECMKP_02585 1.13e-225 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPKECMKP_02586 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPKECMKP_02587 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HPKECMKP_02588 1.38e-155 csrR - - K - - - response regulator
HPKECMKP_02589 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKECMKP_02590 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HPKECMKP_02591 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HPKECMKP_02592 9.59e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPKECMKP_02593 5.08e-122 - - - S - - - SdpI/YhfL protein family
HPKECMKP_02594 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPKECMKP_02595 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HPKECMKP_02596 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPKECMKP_02597 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKECMKP_02598 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
HPKECMKP_02599 1.62e-255 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPKECMKP_02600 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPKECMKP_02601 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPKECMKP_02602 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HPKECMKP_02603 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPKECMKP_02604 1.32e-143 - - - S - - - membrane
HPKECMKP_02605 5.72e-99 - - - K - - - LytTr DNA-binding domain
HPKECMKP_02606 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
HPKECMKP_02607 0.0 - - - S - - - membrane
HPKECMKP_02608 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HPKECMKP_02609 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HPKECMKP_02610 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPKECMKP_02611 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HPKECMKP_02612 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HPKECMKP_02613 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HPKECMKP_02614 9.39e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HPKECMKP_02615 6.68e-89 yqhL - - P - - - Rhodanese-like protein
HPKECMKP_02616 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HPKECMKP_02617 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HPKECMKP_02618 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPKECMKP_02619 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HPKECMKP_02620 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HPKECMKP_02621 1.77e-205 - - - - - - - -
HPKECMKP_02622 1.34e-232 - - - - - - - -
HPKECMKP_02623 2.92e-126 - - - S - - - Protein conserved in bacteria
HPKECMKP_02624 3.11e-73 - - - - - - - -
HPKECMKP_02625 2.97e-41 - - - - - - - -
HPKECMKP_02628 9.81e-27 - - - - - - - -
HPKECMKP_02629 8.15e-125 - - - K - - - Transcriptional regulator
HPKECMKP_02630 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HPKECMKP_02631 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HPKECMKP_02632 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HPKECMKP_02633 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HPKECMKP_02634 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPKECMKP_02635 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HPKECMKP_02636 9.43e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPKECMKP_02637 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPKECMKP_02638 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPKECMKP_02639 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPKECMKP_02640 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPKECMKP_02641 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HPKECMKP_02642 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HPKECMKP_02643 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HPKECMKP_02644 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_02645 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_02646 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPKECMKP_02647 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_02648 8.28e-73 - - - - - - - -
HPKECMKP_02649 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HPKECMKP_02650 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPKECMKP_02651 2.05e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPKECMKP_02652 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPKECMKP_02653 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPKECMKP_02654 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPKECMKP_02655 9.35e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HPKECMKP_02656 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HPKECMKP_02657 3.45e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPKECMKP_02658 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HPKECMKP_02659 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HPKECMKP_02660 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HPKECMKP_02661 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HPKECMKP_02662 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HPKECMKP_02663 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPKECMKP_02664 3.6e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPKECMKP_02665 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPKECMKP_02666 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPKECMKP_02667 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HPKECMKP_02668 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPKECMKP_02669 1.41e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPKECMKP_02670 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPKECMKP_02671 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HPKECMKP_02672 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HPKECMKP_02673 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPKECMKP_02674 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HPKECMKP_02675 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPKECMKP_02676 8.49e-66 - - - - - - - -
HPKECMKP_02677 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HPKECMKP_02678 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HPKECMKP_02679 9.06e-112 - - - - - - - -
HPKECMKP_02680 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HPKECMKP_02681 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HPKECMKP_02683 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HPKECMKP_02684 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HPKECMKP_02685 6.03e-226 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPKECMKP_02686 5.93e-166 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HPKECMKP_02687 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HPKECMKP_02688 1.54e-206 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPKECMKP_02689 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPKECMKP_02690 5.89e-126 entB - - Q - - - Isochorismatase family
HPKECMKP_02691 2.04e-226 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HPKECMKP_02692 7.94e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
HPKECMKP_02693 1.01e-155 - - - E - - - glutamate:sodium symporter activity
HPKECMKP_02694 1.51e-106 - - - E - - - glutamate:sodium symporter activity
HPKECMKP_02695 3.38e-274 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HPKECMKP_02696 1.89e-252 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HPKECMKP_02697 5.19e-78 - - - S - - - Protein of unknown function (DUF1648)
HPKECMKP_02699 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKECMKP_02700 1.62e-229 yneE - - K - - - Transcriptional regulator
HPKECMKP_02701 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPKECMKP_02702 4.64e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPKECMKP_02703 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPKECMKP_02704 5.75e-214 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HPKECMKP_02705 5.14e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HPKECMKP_02706 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPKECMKP_02707 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPKECMKP_02708 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HPKECMKP_02709 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HPKECMKP_02710 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPKECMKP_02711 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HPKECMKP_02712 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HPKECMKP_02713 8.32e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HPKECMKP_02714 1.22e-160 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HPKECMKP_02715 3.06e-206 - - - K - - - LysR substrate binding domain
HPKECMKP_02716 2.01e-113 ykhA - - I - - - Thioesterase superfamily
HPKECMKP_02717 3.61e-245 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPKECMKP_02718 1.22e-120 - - - K - - - transcriptional regulator
HPKECMKP_02719 0.0 - - - EGP - - - Major Facilitator
HPKECMKP_02720 1.14e-193 - - - O - - - Band 7 protein
HPKECMKP_02721 8.58e-71 - - - - - - - -
HPKECMKP_02722 4.04e-33 - - - - - - - -
HPKECMKP_02723 9.75e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HPKECMKP_02724 5.76e-146 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HPKECMKP_02725 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HPKECMKP_02726 2.05e-55 - - - - - - - -
HPKECMKP_02727 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HPKECMKP_02728 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
HPKECMKP_02729 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
HPKECMKP_02730 2.96e-210 - - - I - - - Diacylglycerol kinase catalytic domain
HPKECMKP_02731 7.21e-47 - - - - - - - -
HPKECMKP_02732 5.79e-21 - - - - - - - -
HPKECMKP_02733 2.22e-55 - - - S - - - transglycosylase associated protein
HPKECMKP_02734 4e-40 - - - S - - - CsbD-like
HPKECMKP_02735 1.06e-53 - - - - - - - -
HPKECMKP_02736 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKECMKP_02737 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HPKECMKP_02738 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPKECMKP_02739 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HPKECMKP_02740 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HPKECMKP_02741 1.52e-67 - - - - - - - -
HPKECMKP_02742 3.23e-58 - - - - - - - -
HPKECMKP_02743 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPKECMKP_02744 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HPKECMKP_02745 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HPKECMKP_02746 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HPKECMKP_02747 6.56e-148 - - - S - - - Domain of unknown function (DUF4767)
HPKECMKP_02748 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HPKECMKP_02749 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HPKECMKP_02750 5.76e-148 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HPKECMKP_02751 2.09e-66 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HPKECMKP_02752 3.51e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPKECMKP_02753 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HPKECMKP_02754 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HPKECMKP_02755 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HPKECMKP_02756 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HPKECMKP_02757 4.2e-106 ypmB - - S - - - protein conserved in bacteria
HPKECMKP_02758 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HPKECMKP_02759 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HPKECMKP_02760 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HPKECMKP_02761 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPKECMKP_02762 1.41e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKECMKP_02763 3.19e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HPKECMKP_02764 1.31e-109 - - - T - - - Universal stress protein family
HPKECMKP_02765 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKECMKP_02766 1.98e-234 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HPKECMKP_02767 2.21e-226 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_02768 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HPKECMKP_02769 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPKECMKP_02770 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HPKECMKP_02771 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPKECMKP_02773 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HPKECMKP_02774 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HPKECMKP_02775 7.86e-96 - - - S - - - SnoaL-like domain
HPKECMKP_02776 1.67e-307 - - - M - - - Glycosyltransferase, group 2 family protein
HPKECMKP_02777 4.92e-267 mccF - - V - - - LD-carboxypeptidase
HPKECMKP_02778 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
HPKECMKP_02779 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
HPKECMKP_02780 1.38e-232 - - - V - - - LD-carboxypeptidase
HPKECMKP_02781 4.35e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HPKECMKP_02782 2.69e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HPKECMKP_02783 6.5e-247 - - - - - - - -
HPKECMKP_02784 7.14e-185 - - - S - - - hydrolase activity, acting on ester bonds
HPKECMKP_02785 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HPKECMKP_02786 4.66e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HPKECMKP_02787 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
HPKECMKP_02788 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HPKECMKP_02789 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPKECMKP_02790 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKECMKP_02791 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPKECMKP_02792 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HPKECMKP_02793 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKECMKP_02794 9.58e-144 - - - G - - - Phosphoglycerate mutase family
HPKECMKP_02795 8.72e-90 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HPKECMKP_02797 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HPKECMKP_02798 4.92e-91 - - - S - - - LuxR family transcriptional regulator
HPKECMKP_02799 5.68e-175 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HPKECMKP_02801 4.59e-118 - - - F - - - NUDIX domain
HPKECMKP_02802 1.77e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKECMKP_02803 1.6e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HPKECMKP_02804 0.0 FbpA - - K - - - Fibronectin-binding protein
HPKECMKP_02805 1.97e-87 - - - K - - - Transcriptional regulator
HPKECMKP_02806 1.11e-205 - - - S - - - EDD domain protein, DegV family
HPKECMKP_02807 3.65e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HPKECMKP_02808 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
HPKECMKP_02809 2.15e-33 - - - - - - - -
HPKECMKP_02810 2.37e-65 - - - - - - - -
HPKECMKP_02811 4.17e-192 - - - C - - - Domain of unknown function (DUF4931)
HPKECMKP_02812 2.44e-267 pmrB - - EGP - - - Major Facilitator Superfamily
HPKECMKP_02814 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HPKECMKP_02815 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HPKECMKP_02816 1.05e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HPKECMKP_02817 7.45e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKECMKP_02818 1.09e-178 - - - - - - - -
HPKECMKP_02819 1.84e-76 - - - - - - - -
HPKECMKP_02820 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HPKECMKP_02821 3.71e-286 - - - - - - - -
HPKECMKP_02822 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HPKECMKP_02823 6.51e-247 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HPKECMKP_02824 4.99e-274 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPKECMKP_02825 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPKECMKP_02826 1.4e-122 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HPKECMKP_02827 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKECMKP_02828 5.7e-220 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)