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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MKEKHDDM_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKEKHDDM_00002	3.45e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKEKHDDM_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MKEKHDDM_00004	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKEKHDDM_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MKEKHDDM_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKEKHDDM_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKEKHDDM_00008	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00011	8.24e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
MKEKHDDM_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKEKHDDM_00013	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKEKHDDM_00014	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKEKHDDM_00015	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKEKHDDM_00016	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKEKHDDM_00017	2.41e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MKEKHDDM_00019	7.51e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MKEKHDDM_00020	4.04e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MKEKHDDM_00021	1.75e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MKEKHDDM_00022	5.85e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MKEKHDDM_00023	2.89e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKEKHDDM_00024	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKEKHDDM_00025	2.41e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKEKHDDM_00026	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKEKHDDM_00027	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MKEKHDDM_00028	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MKEKHDDM_00029	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00032	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MKEKHDDM_00033	5.91e-136	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKEKHDDM_00034	8.84e-247	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MKEKHDDM_00035	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MKEKHDDM_00036	7.75e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKEKHDDM_00037	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00038	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MKEKHDDM_00039	1.1e-232	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MKEKHDDM_00040	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MKEKHDDM_00041	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MKEKHDDM_00042	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MKEKHDDM_00043	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MKEKHDDM_00044	1.58e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKEKHDDM_00045	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MKEKHDDM_00046	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKEKHDDM_00047	6.12e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MKEKHDDM_00048	2.49e-310	yabE	-	-	T	-	-	-	protein conserved in bacteria
MKEKHDDM_00049	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKEKHDDM_00050	8.41e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKEKHDDM_00051	1.41e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MKEKHDDM_00052	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00053	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MKEKHDDM_00054	5.51e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKEKHDDM_00055	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MKEKHDDM_00056	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MKEKHDDM_00057	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MKEKHDDM_00058	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKEKHDDM_00059	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKEKHDDM_00060	2.52e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKEKHDDM_00061	1.74e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKEKHDDM_00062	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MKEKHDDM_00063	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKEKHDDM_00064	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MKEKHDDM_00065	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_00066	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MKEKHDDM_00067	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MKEKHDDM_00068	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MKEKHDDM_00069	4.79e-134	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MKEKHDDM_00070	1.2e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MKEKHDDM_00071	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKEKHDDM_00074	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MKEKHDDM_00075	3.79e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKEKHDDM_00076	1.57e-234	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKEKHDDM_00077	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKEKHDDM_00078	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MKEKHDDM_00079	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKEKHDDM_00080	8.14e-178	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKEKHDDM_00081	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKEKHDDM_00082	1.04e-196	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MKEKHDDM_00083	2.55e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKEKHDDM_00084	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKEKHDDM_00085	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MKEKHDDM_00086	3.45e-207	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MKEKHDDM_00087	2.24e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKEKHDDM_00088	4.62e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKEKHDDM_00089	8.2e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKEKHDDM_00090	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
MKEKHDDM_00091	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKEKHDDM_00092	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MKEKHDDM_00093	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00103	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00104	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MKEKHDDM_00105	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MKEKHDDM_00106	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MKEKHDDM_00107	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MKEKHDDM_00108	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKEKHDDM_00109	1.8e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKEKHDDM_00110	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MKEKHDDM_00111	1.23e-160	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKEKHDDM_00112	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKEKHDDM_00113	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKEKHDDM_00114	3.16e-151	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MKEKHDDM_00115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKEKHDDM_00116	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKEKHDDM_00117	2.04e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKEKHDDM_00118	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MKEKHDDM_00119	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MKEKHDDM_00120	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKEKHDDM_00121	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MKEKHDDM_00122	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKEKHDDM_00123	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKEKHDDM_00124	2.33e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKEKHDDM_00125	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKEKHDDM_00126	7.25e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MKEKHDDM_00127	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKEKHDDM_00128	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKEKHDDM_00129	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MKEKHDDM_00130	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKEKHDDM_00131	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKEKHDDM_00132	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKEKHDDM_00133	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKEKHDDM_00134	8.14e-240	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MKEKHDDM_00135	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MKEKHDDM_00136	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKEKHDDM_00137	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MKEKHDDM_00138	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKEKHDDM_00139	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKEKHDDM_00140	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKEKHDDM_00141	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKEKHDDM_00142	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKEKHDDM_00143	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKEKHDDM_00144	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MKEKHDDM_00145	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKEKHDDM_00146	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKEKHDDM_00147	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKEKHDDM_00148	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKEKHDDM_00149	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKEKHDDM_00150	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKEKHDDM_00151	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKEKHDDM_00152	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKEKHDDM_00153	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKEKHDDM_00154	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MKEKHDDM_00155	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKEKHDDM_00156	7.75e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKEKHDDM_00157	1.46e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKEKHDDM_00158	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKEKHDDM_00159	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKEKHDDM_00160	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MKEKHDDM_00161	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKEKHDDM_00162	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKEKHDDM_00163	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKEKHDDM_00164	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MKEKHDDM_00165	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKEKHDDM_00166	4.91e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKEKHDDM_00167	1.13e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKEKHDDM_00168	8.74e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKEKHDDM_00169	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKEKHDDM_00170	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MKEKHDDM_00171	1.76e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MKEKHDDM_00172	3.03e-106	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MKEKHDDM_00173	1.31e-102	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MKEKHDDM_00174	1.98e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKEKHDDM_00175	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKEKHDDM_00176	6.81e-103	gerD	-	-	-	ko:K06294	-	ko00000	-
MKEKHDDM_00177	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MKEKHDDM_00178	9.06e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MKEKHDDM_00179	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00185	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00186	2.45e-271	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MKEKHDDM_00187	3.65e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKEKHDDM_00188	1.1e-230	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MKEKHDDM_00189	9.77e-257	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MKEKHDDM_00190	4.74e-289	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MKEKHDDM_00191	1.54e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
MKEKHDDM_00192	1.26e-148	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MKEKHDDM_00193	5.83e-229	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_00194	8.92e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_00195	2.1e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MKEKHDDM_00196	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MKEKHDDM_00197	3.7e-299	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00198	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MKEKHDDM_00199	3.25e-311	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MKEKHDDM_00200	7.14e-311	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_00201	9.86e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKEKHDDM_00202	1.82e-112	ybbJ	-	-	J	-	-	-	acetyltransferase
MKEKHDDM_00203	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MKEKHDDM_00209	1.87e-126	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00210	1.11e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MKEKHDDM_00211	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKEKHDDM_00212	2.59e-300	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00213	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKEKHDDM_00214	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKEKHDDM_00215	2.49e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKEKHDDM_00216	2.02e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKEKHDDM_00217	1.07e-124	ybdN	-	-	-	-	-	-	-
MKEKHDDM_00218	2.61e-166	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MKEKHDDM_00219	7.27e-207	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MKEKHDDM_00220	4.26e-135	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MKEKHDDM_00221	1.41e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MKEKHDDM_00222	9.32e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_00223	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_00224	7.81e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKEKHDDM_00225	1.01e-131	-	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_00226	1.24e-104	-	-	-	KT	-	-	-	helix_turn_helix, Lux Regulon
MKEKHDDM_00227	9.14e-172	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00228	6.11e-184	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_00229	1.89e-154	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_00230	1.62e-19	-	-	-	-	-	-	-	-
MKEKHDDM_00231	2.79e-73	-	-	-	Q	-	-	-	Thioesterase domain
MKEKHDDM_00232	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
MKEKHDDM_00233	0.0	nrsB	-	-	Q	ko:K15654,ko:K16094,ko:K16095	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Non-ribosomal peptide synthetase modules and related proteins
MKEKHDDM_00234	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
MKEKHDDM_00235	3.86e-150	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	PFAM Acyl transferase
MKEKHDDM_00236	0.0	-	-	-	Q	-	-	-	Beta-ketoacyl synthase
MKEKHDDM_00237	0.0	-	-	-	Q	-	-	-	Polyketide synthase modules and related proteins
MKEKHDDM_00238	9.09e-122	-	-	-	Q	-	-	-	Flavin containing amine oxidoreductase
MKEKHDDM_00239	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
MKEKHDDM_00240	8.47e-51	-	-	-	Q	-	-	-	Dimerisation domain
MKEKHDDM_00241	1.55e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
MKEKHDDM_00242	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MKEKHDDM_00243	5.07e-144	yqeB	-	-	-	-	-	-	-
MKEKHDDM_00244	7.84e-55	ybyB	-	-	-	-	-	-	-
MKEKHDDM_00245	0.0	ybeC	-	-	E	-	-	-	amino acid
MKEKHDDM_00246	9.18e-64	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKEKHDDM_00248	2.09e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MKEKHDDM_00249	1.04e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MKEKHDDM_00250	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MKEKHDDM_00251	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MKEKHDDM_00252	3.34e-266	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MKEKHDDM_00254	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MKEKHDDM_00255	4e-44	-	-	-	-	-	-	-	-
MKEKHDDM_00256	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKEKHDDM_00257	1.23e-254	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MKEKHDDM_00258	6.53e-271	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKEKHDDM_00259	3.15e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKEKHDDM_00260	8.6e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MKEKHDDM_00261	3.05e-194	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MKEKHDDM_00262	2.13e-55	ybfN	-	-	-	-	-	-	-
MKEKHDDM_00263	5.76e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MKEKHDDM_00264	8.22e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKEKHDDM_00265	2.05e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MKEKHDDM_00266	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKEKHDDM_00267	1.51e-232	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MKEKHDDM_00268	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MKEKHDDM_00269	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MKEKHDDM_00270	5.12e-278	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_00271	3.36e-220	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MKEKHDDM_00272	2.88e-44	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MKEKHDDM_00273	6.9e-35	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MKEKHDDM_00274	3.02e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKEKHDDM_00275	1.15e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MKEKHDDM_00276	1.24e-234	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKEKHDDM_00277	9.37e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MKEKHDDM_00278	1.54e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
MKEKHDDM_00279	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKEKHDDM_00280	1.05e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MKEKHDDM_00281	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MKEKHDDM_00282	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKEKHDDM_00283	2.86e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKEKHDDM_00284	4.88e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKEKHDDM_00285	1.41e-265	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MKEKHDDM_00286	1.61e-309	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MKEKHDDM_00287	2.19e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MKEKHDDM_00288	3.55e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MKEKHDDM_00289	5.23e-144	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKEKHDDM_00290	1.68e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MKEKHDDM_00291	1.54e-218	yccK	-	-	C	-	-	-	Aldo keto reductase
MKEKHDDM_00292	1.13e-226	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MKEKHDDM_00293	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00294	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00295	6.25e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKEKHDDM_00296	2.86e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_00297	1.05e-179	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MKEKHDDM_00298	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKEKHDDM_00299	1.22e-212	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MKEKHDDM_00300	1.4e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKEKHDDM_00301	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKEKHDDM_00302	1.2e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_00303	1.16e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MKEKHDDM_00304	3.63e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MKEKHDDM_00305	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MKEKHDDM_00306	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MKEKHDDM_00307	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MKEKHDDM_00308	1.17e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
MKEKHDDM_00309	5.22e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MKEKHDDM_00310	1.28e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MKEKHDDM_00311	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKEKHDDM_00312	9.95e-211	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKEKHDDM_00313	1.37e-271	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MKEKHDDM_00314	8.03e-294	ycgA	-	-	S	-	-	-	Membrane
MKEKHDDM_00315	4.41e-106	ycgB	-	-	-	-	-	-	-
MKEKHDDM_00316	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MKEKHDDM_00317	9.37e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MKEKHDDM_00318	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MKEKHDDM_00319	6.92e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_00320	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MKEKHDDM_00321	6.95e-191	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MKEKHDDM_00322	3.84e-313	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_00323	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MKEKHDDM_00324	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKEKHDDM_00325	6.96e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MKEKHDDM_00326	3.74e-138	tmrB	-	-	S	-	-	-	AAA domain
MKEKHDDM_00327	7.76e-188	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MKEKHDDM_00328	3.9e-303	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_00329	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKEKHDDM_00330	2.41e-235	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MKEKHDDM_00331	4.33e-189	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MKEKHDDM_00332	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKEKHDDM_00333	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKEKHDDM_00334	1.28e-310	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKEKHDDM_00335	1.43e-290	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MKEKHDDM_00336	4.73e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MKEKHDDM_00337	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKEKHDDM_00338	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MKEKHDDM_00339	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKEKHDDM_00340	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKEKHDDM_00341	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MKEKHDDM_00342	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKEKHDDM_00343	3.74e-285	yciC	-	-	S	-	-	-	GTPases (G3E family)
MKEKHDDM_00344	2.06e-280	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKEKHDDM_00345	3.65e-94	yckC	-	-	S	-	-	-	membrane
MKEKHDDM_00346	3.31e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MKEKHDDM_00347	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKEKHDDM_00348	1.87e-88	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MKEKHDDM_00349	2.19e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MKEKHDDM_00350	1.04e-122	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MKEKHDDM_00351	3.14e-139	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MKEKHDDM_00352	1.38e-82	hxlR	-	-	K	-	-	-	transcriptional
MKEKHDDM_00353	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_00354	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_00355	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MKEKHDDM_00356	3.56e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MKEKHDDM_00357	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
MKEKHDDM_00358	3.86e-84	-	-	-	S	-	-	-	YcxB-like protein
MKEKHDDM_00359	4.54e-216	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MKEKHDDM_00360	3.41e-313	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MKEKHDDM_00361	5.28e-167	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MKEKHDDM_00362	7.33e-143	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MKEKHDDM_00363	7.96e-169	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKEKHDDM_00364	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKEKHDDM_00365	1.14e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MKEKHDDM_00366	3.45e-205	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MKEKHDDM_00367	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKEKHDDM_00368	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MKEKHDDM_00369	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MKEKHDDM_00370	8.28e-101	yclD	-	-	-	-	-	-	-
MKEKHDDM_00371	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MKEKHDDM_00372	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MKEKHDDM_00374	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MKEKHDDM_00375	5.93e-302	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MKEKHDDM_00376	9.23e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MKEKHDDM_00377	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_00378	3.64e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKEKHDDM_00379	7.09e-180	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKEKHDDM_00380	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKEKHDDM_00381	5.6e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00382	5.04e-279	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MKEKHDDM_00383	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MKEKHDDM_00384	4.28e-154	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKEKHDDM_00385	1.49e-310	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MKEKHDDM_00386	9.08e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_00387	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MKEKHDDM_00388	5.98e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKEKHDDM_00390	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKEKHDDM_00391	7.78e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_00392	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_00393	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00394	6.82e-224	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MKEKHDDM_00395	2.1e-315	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MKEKHDDM_00396	1.05e-195	ycnC	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00397	1.38e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MKEKHDDM_00398	1.97e-59	ycnE	-	-	S	-	-	-	Monooxygenase
MKEKHDDM_00399	1.37e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKEKHDDM_00400	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKEKHDDM_00401	7.59e-288	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKEKHDDM_00402	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKEKHDDM_00403	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MKEKHDDM_00404	2.4e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_00405	2.05e-131	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00406	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MKEKHDDM_00407	4.26e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKEKHDDM_00408	9.6e-73	-	-	-	-	-	-	-	-
MKEKHDDM_00409	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MKEKHDDM_00410	1.38e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MKEKHDDM_00411	1.92e-262	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MKEKHDDM_00412	8.28e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MKEKHDDM_00414	4.66e-178	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MKEKHDDM_00415	6.12e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MKEKHDDM_00416	2.18e-270	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MKEKHDDM_00417	2.07e-193	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MKEKHDDM_00418	1.98e-176	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MKEKHDDM_00419	2.43e-240	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MKEKHDDM_00420	9.38e-167	kipR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00421	9.09e-149	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MKEKHDDM_00423	9.52e-72	yczJ	-	-	S	-	-	-	biosynthesis
MKEKHDDM_00424	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MKEKHDDM_00425	1.05e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
MKEKHDDM_00426	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MKEKHDDM_00427	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MKEKHDDM_00428	3.82e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_00429	6.76e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MKEKHDDM_00430	3.88e-147	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKEKHDDM_00431	1.83e-101	ydaG	-	-	S	-	-	-	general stress protein
MKEKHDDM_00432	4.39e-177	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MKEKHDDM_00433	5.59e-64	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MKEKHDDM_00434	1.61e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MKEKHDDM_00435	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKEKHDDM_00436	1.7e-259	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKEKHDDM_00437	5.39e-189	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MKEKHDDM_00438	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MKEKHDDM_00439	4.54e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MKEKHDDM_00440	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MKEKHDDM_00441	0.0	ydaO	-	-	E	-	-	-	amino acid
MKEKHDDM_00442	1.08e-97	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MKEKHDDM_00443	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MKEKHDDM_00444	8.7e-34	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MKEKHDDM_00445	6.19e-110	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKEKHDDM_00446	2.07e-83	-	-	-	-	-	-	-	-
MKEKHDDM_00447	1.42e-268	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MKEKHDDM_00449	1.81e-17	-	-	-	-	-	-	-	-
MKEKHDDM_00451	2.17e-115	-	-	-	-	-	-	-	-
MKEKHDDM_00452	7.01e-129	-	-	-	-	-	-	-	-
MKEKHDDM_00453	6.14e-53	-	-	-	-	-	-	-	-
MKEKHDDM_00454	1.87e-288	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MKEKHDDM_00456	1.13e-44	ydaT	-	-	-	-	-	-	-
MKEKHDDM_00457	3.75e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MKEKHDDM_00458	4.77e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MKEKHDDM_00459	2.56e-180	ydbA	-	-	P	-	-	-	EcsC protein family
MKEKHDDM_00460	6.55e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MKEKHDDM_00461	9.34e-85	ydbB	-	-	G	-	-	-	Cupin domain
MKEKHDDM_00462	5.01e-80	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MKEKHDDM_00463	1.35e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MKEKHDDM_00464	9e-254	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKEKHDDM_00465	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKEKHDDM_00466	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKEKHDDM_00467	3.91e-287	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKEKHDDM_00468	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
MKEKHDDM_00469	4.79e-221	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00470	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKEKHDDM_00471	2.29e-70	ydbL	-	-	-	-	-	-	-
MKEKHDDM_00472	7.51e-262	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MKEKHDDM_00473	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
MKEKHDDM_00474	1.33e-13	-	-	-	S	-	-	-	Fur-regulated basic protein A
MKEKHDDM_00475	2e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKEKHDDM_00476	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
MKEKHDDM_00477	2.16e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MKEKHDDM_00478	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKEKHDDM_00479	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKEKHDDM_00480	2.18e-96	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MKEKHDDM_00481	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MKEKHDDM_00482	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MKEKHDDM_00483	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKEKHDDM_00484	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MKEKHDDM_00485	1.39e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKEKHDDM_00486	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MKEKHDDM_00487	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MKEKHDDM_00488	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MKEKHDDM_00489	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MKEKHDDM_00490	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MKEKHDDM_00491	8.83e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MKEKHDDM_00492	8.04e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MKEKHDDM_00493	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MKEKHDDM_00494	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_00495	3.33e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MKEKHDDM_00496	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MKEKHDDM_00497	1.78e-21	-	-	-	-	-	-	-	-
MKEKHDDM_00498	1.74e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MKEKHDDM_00506	7.51e-186	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKEKHDDM_00507	2.86e-72	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MKEKHDDM_00508	6.44e-58	-	-	-	K	-	-	-	Transcriptional
MKEKHDDM_00509	2.84e-19	-	-	-	-	-	-	-	-
MKEKHDDM_00511	1.87e-50	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MKEKHDDM_00512	4.94e-306	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
MKEKHDDM_00513	4.62e-232	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
MKEKHDDM_00516	7.07e-53	yddA	-	-	-	-	-	-	-
MKEKHDDM_00518	1.82e-165	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
MKEKHDDM_00519	2.72e-33	yddC	-	-	-	-	-	-	-
MKEKHDDM_00520	3.73e-97	yddD	-	-	S	-	-	-	TcpE family
MKEKHDDM_00521	0.0	yddE	-	-	S	-	-	-	AAA-like domain
MKEKHDDM_00522	5.83e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
MKEKHDDM_00523	4.48e-253	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
MKEKHDDM_00524	5.09e-201	yddH	-	-	M	-	-	-	Lysozyme-like
MKEKHDDM_00525	7.7e-73	yddI	-	-	-	-	-	-	-
MKEKHDDM_00526	3.56e-47	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MKEKHDDM_00529	3.9e-86	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_00531	5.45e-80	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
MKEKHDDM_00532	1.35e-124	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MKEKHDDM_00533	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
MKEKHDDM_00534	1.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00535	8.64e-112	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MKEKHDDM_00536	3.54e-95	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MKEKHDDM_00537	1.16e-82	-	-	-	S	-	-	-	YjbR
MKEKHDDM_00538	2.35e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00539	6.64e-146	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MKEKHDDM_00540	8.94e-250	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MKEKHDDM_00541	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MKEKHDDM_00542	2.07e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MKEKHDDM_00543	4.82e-155	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MKEKHDDM_00544	3.77e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MKEKHDDM_00545	8.2e-68	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKEKHDDM_00546	7.19e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
MKEKHDDM_00547	2.03e-100	-	-	-	S	-	-	-	DinB superfamily
MKEKHDDM_00548	1.49e-84	-	-	-	G	-	-	-	Cupin domain
MKEKHDDM_00551	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MKEKHDDM_00552	2.63e-41	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_00553	5.97e-197	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MKEKHDDM_00554	6.82e-251	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MKEKHDDM_00556	1.15e-190	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKEKHDDM_00558	3.53e-255	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MKEKHDDM_00559	2.05e-69	ydeH	-	-	-	-	-	-	-
MKEKHDDM_00560	2.02e-203	-	-	-	S	-	-	-	Sodium Bile acid symporter family
MKEKHDDM_00561	5.46e-259	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MKEKHDDM_00562	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MKEKHDDM_00563	1.59e-287	nhaC_1	-	-	C	-	-	-	antiporter
MKEKHDDM_00564	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKEKHDDM_00565	1.2e-145	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_00567	1.52e-250	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MKEKHDDM_00568	1.2e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00569	8.71e-201	ydeK	-	-	EG	-	-	-	-transporter
MKEKHDDM_00570	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKEKHDDM_00571	5.09e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MKEKHDDM_00572	3.42e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
MKEKHDDM_00573	1.24e-281	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKEKHDDM_00574	2.76e-83	yraF	-	-	M	-	-	-	Spore coat protein
MKEKHDDM_00575	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
MKEKHDDM_00576	4.58e-264	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_00577	6.89e-143	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_00578	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MKEKHDDM_00579	1.97e-170	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MKEKHDDM_00580	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MKEKHDDM_00581	1.91e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_00582	3.51e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_00583	4.41e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MKEKHDDM_00584	8.22e-270	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MKEKHDDM_00585	3.76e-286	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKEKHDDM_00586	2.24e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKEKHDDM_00587	5.2e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKEKHDDM_00588	1.99e-104	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MKEKHDDM_00589	4.83e-15	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKEKHDDM_00590	2.73e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MKEKHDDM_00591	6.64e-188	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKEKHDDM_00592	6.25e-107	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MKEKHDDM_00595	3.43e-62	-	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MKEKHDDM_00596	1.09e-152	ydhC	-	-	K	-	-	-	FCD
MKEKHDDM_00597	5.57e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKEKHDDM_00600	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MKEKHDDM_00602	4.3e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MKEKHDDM_00603	3.18e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKEKHDDM_00604	7.17e-172	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MKEKHDDM_00605	1.88e-153	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MKEKHDDM_00606	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MKEKHDDM_00607	1.48e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MKEKHDDM_00608	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKEKHDDM_00609	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00610	0.0	ybeC	-	-	E	-	-	-	amino acid
MKEKHDDM_00611	4.41e-214	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MKEKHDDM_00612	2.06e-112	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MKEKHDDM_00613	8.11e-237	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MKEKHDDM_00614	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKEKHDDM_00617	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00620	1.45e-235	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKEKHDDM_00621	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MKEKHDDM_00622	3.41e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MKEKHDDM_00623	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKEKHDDM_00624	9.22e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKEKHDDM_00625	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MKEKHDDM_00626	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MKEKHDDM_00627	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKEKHDDM_00628	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKEKHDDM_00629	1.65e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKEKHDDM_00630	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MKEKHDDM_00631	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MKEKHDDM_00632	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKEKHDDM_00633	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKEKHDDM_00634	7.07e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
MKEKHDDM_00635	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MKEKHDDM_00636	1.51e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MKEKHDDM_00637	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MKEKHDDM_00638	1.73e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MKEKHDDM_00639	5.98e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MKEKHDDM_00640	1.36e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MKEKHDDM_00641	1.55e-229	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKEKHDDM_00642	2.24e-162	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MKEKHDDM_00643	6.64e-216	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MKEKHDDM_00644	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MKEKHDDM_00645	1.32e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MKEKHDDM_00646	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00647	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MKEKHDDM_00648	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
MKEKHDDM_00649	4.98e-195	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MKEKHDDM_00651	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MKEKHDDM_00652	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MKEKHDDM_00653	1.77e-314	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_00654	7.15e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKEKHDDM_00655	5.62e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MKEKHDDM_00656	2.69e-275	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MKEKHDDM_00657	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MKEKHDDM_00658	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MKEKHDDM_00659	4.04e-166	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_00660	2.31e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00661	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MKEKHDDM_00662	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKEKHDDM_00663	2.02e-173	yebC	-	-	M	-	-	-	Membrane
MKEKHDDM_00665	4.41e-119	yebE	-	-	S	-	-	-	UPF0316 protein
MKEKHDDM_00666	6.56e-40	yebG	-	-	S	-	-	-	NETI protein
MKEKHDDM_00667	1.13e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKEKHDDM_00668	1.31e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKEKHDDM_00669	6.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKEKHDDM_00670	5.86e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MKEKHDDM_00671	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKEKHDDM_00672	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKEKHDDM_00673	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKEKHDDM_00674	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKEKHDDM_00675	5.33e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MKEKHDDM_00676	7.3e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKEKHDDM_00677	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MKEKHDDM_00678	3.29e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MKEKHDDM_00679	8.43e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MKEKHDDM_00680	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MKEKHDDM_00681	4.95e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MKEKHDDM_00682	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00683	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MKEKHDDM_00684	1.76e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKEKHDDM_00685	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MKEKHDDM_00686	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKEKHDDM_00687	4.36e-283	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MKEKHDDM_00688	1.48e-247	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MKEKHDDM_00689	1.68e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MKEKHDDM_00690	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKEKHDDM_00691	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKEKHDDM_00692	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKEKHDDM_00693	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKEKHDDM_00694	2.23e-197	yerO	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00695	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKEKHDDM_00696	4.95e-216	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKEKHDDM_00697	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKEKHDDM_00699	9.62e-203	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MKEKHDDM_00700	6.78e-176	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_00701	5.79e-107	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MKEKHDDM_00702	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MKEKHDDM_00703	1.05e-24	-	-	-	-	-	-	-	-
MKEKHDDM_00704	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MKEKHDDM_00706	4.61e-61	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MKEKHDDM_00707	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MKEKHDDM_00708	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MKEKHDDM_00709	4.33e-127	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKEKHDDM_00710	4.2e-05	-	-	-	-	-	-	-	-
MKEKHDDM_00711	3.01e-155	yetF	-	-	S	-	-	-	membrane
MKEKHDDM_00712	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MKEKHDDM_00713	7.63e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_00714	4.42e-197	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKEKHDDM_00715	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MKEKHDDM_00716	1.06e-72	-	-	-	H	-	-	-	riboflavin kinase activity
MKEKHDDM_00717	2.19e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MKEKHDDM_00719	2.08e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_00720	9.54e-262	yetM	-	-	CH	-	-	-	FAD binding domain
MKEKHDDM_00721	1.38e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MKEKHDDM_00722	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MKEKHDDM_00724	3.38e-66	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MKEKHDDM_00725	6.49e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKEKHDDM_00726	5.34e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_00727	2.05e-07	-	-	-	S	-	-	-	protein homooligomerization
MKEKHDDM_00729	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKEKHDDM_00730	1.2e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MKEKHDDM_00731	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MKEKHDDM_00732	4.47e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MKEKHDDM_00733	1.46e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MKEKHDDM_00734	1.2e-239	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MKEKHDDM_00735	2.7e-278	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_00736	8.39e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MKEKHDDM_00737	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKEKHDDM_00738	5.49e-167	yfmS	-	-	NT	-	-	-	chemotaxis protein
MKEKHDDM_00739	8.54e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKEKHDDM_00740	9.89e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKEKHDDM_00741	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKEKHDDM_00742	8.7e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MKEKHDDM_00743	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MKEKHDDM_00744	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKEKHDDM_00745	1.53e-265	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MKEKHDDM_00746	4e-84	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MKEKHDDM_00747	4.91e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MKEKHDDM_00748	1.1e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MKEKHDDM_00749	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MKEKHDDM_00750	9.25e-308	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MKEKHDDM_00751	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MKEKHDDM_00753	2.07e-93	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
MKEKHDDM_00754	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKEKHDDM_00755	5.4e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MKEKHDDM_00756	1.13e-225	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKEKHDDM_00757	1.36e-285	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MKEKHDDM_00758	8.08e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKEKHDDM_00759	6.08e-279	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKEKHDDM_00760	3.93e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MKEKHDDM_00761	2.51e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_00762	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MKEKHDDM_00763	1.98e-26	yflI	-	-	-	-	-	-	-
MKEKHDDM_00764	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MKEKHDDM_00765	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKEKHDDM_00766	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKEKHDDM_00767	4.75e-96	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MKEKHDDM_00768	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKEKHDDM_00769	4.9e-83	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MKEKHDDM_00770	8.64e-106	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKEKHDDM_00771	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MKEKHDDM_00772	7.28e-51	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MKEKHDDM_00773	5.23e-312	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_00774	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKEKHDDM_00775	9.69e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MKEKHDDM_00776	1.45e-158	frp	-	-	C	-	-	-	nitroreductase
MKEKHDDM_00777	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
MKEKHDDM_00778	2.21e-255	yibE	-	-	S	-	-	-	YibE/F-like protein
MKEKHDDM_00779	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MKEKHDDM_00780	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MKEKHDDM_00781	5.28e-238	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKEKHDDM_00782	3.54e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKEKHDDM_00783	1.18e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKEKHDDM_00784	6.67e-250	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_00785	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MKEKHDDM_00786	2.8e-111	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKEKHDDM_00787	1.76e-68	yfkI	-	-	S	-	-	-	gas vesicle protein
MKEKHDDM_00788	1.37e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MKEKHDDM_00789	6.71e-12	-	-	-	-	-	-	-	-
MKEKHDDM_00790	1.45e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_00791	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MKEKHDDM_00792	5.66e-186	yfkD	-	-	S	-	-	-	YfkD-like protein
MKEKHDDM_00793	5.2e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MKEKHDDM_00794	5.66e-280	yfkA	-	-	S	-	-	-	YfkB-like domain
MKEKHDDM_00795	7.99e-37	yfjT	-	-	-	-	-	-	-
MKEKHDDM_00796	4.36e-199	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MKEKHDDM_00797	2.39e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MKEKHDDM_00799	2.24e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MKEKHDDM_00800	2.85e-207	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKEKHDDM_00801	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKEKHDDM_00802	2.15e-67	-	-	-	S	-	-	-	YfzA-like protein
MKEKHDDM_00804	2.97e-245	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKEKHDDM_00805	1.11e-115	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MKEKHDDM_00806	5.55e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKEKHDDM_00807	3.08e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKEKHDDM_00808	1.09e-271	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKEKHDDM_00809	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKEKHDDM_00810	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MKEKHDDM_00811	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MKEKHDDM_00812	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKEKHDDM_00813	1.28e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MKEKHDDM_00814	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_00815	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKEKHDDM_00816	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKEKHDDM_00817	1.36e-82	yfiD3	-	-	S	-	-	-	DoxX
MKEKHDDM_00818	4.72e-205	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MKEKHDDM_00819	2.08e-214	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKEKHDDM_00820	5.62e-126	padR	-	-	K	-	-	-	transcriptional
MKEKHDDM_00821	4.22e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MKEKHDDM_00822	5.66e-238	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MKEKHDDM_00823	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MKEKHDDM_00824	1.17e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MKEKHDDM_00825	1.14e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MKEKHDDM_00826	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MKEKHDDM_00827	1.38e-108	yfiV	-	-	K	-	-	-	transcriptional
MKEKHDDM_00828	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKEKHDDM_00829	7.89e-213	yfhB	-	-	S	-	-	-	PhzF family
MKEKHDDM_00830	1.17e-137	yfhC	-	-	C	-	-	-	nitroreductase
MKEKHDDM_00831	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
MKEKHDDM_00833	4.94e-214	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MKEKHDDM_00834	3.14e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MKEKHDDM_00835	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MKEKHDDM_00836	4.06e-268	yfhI	-	-	EGP	-	-	-	-transporter
MKEKHDDM_00838	2.45e-216	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MKEKHDDM_00839	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
MKEKHDDM_00840	9.84e-123	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MKEKHDDM_00841	1.48e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MKEKHDDM_00842	9.66e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKEKHDDM_00843	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKEKHDDM_00844	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MKEKHDDM_00845	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MKEKHDDM_00846	4.55e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MKEKHDDM_00847	2.54e-50	yfhS	-	-	-	-	-	-	-
MKEKHDDM_00848	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_00849	4.77e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MKEKHDDM_00850	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MKEKHDDM_00851	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MKEKHDDM_00852	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MKEKHDDM_00853	5.48e-239	ygaE	-	-	S	-	-	-	Membrane
MKEKHDDM_00854	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKEKHDDM_00855	1.39e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MKEKHDDM_00856	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MKEKHDDM_00857	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MKEKHDDM_00858	4.57e-212	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MKEKHDDM_00859	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_00875	3.51e-294	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
MKEKHDDM_00876	9.41e-75	-	-	-	L	-	-	-	Eco47II restriction endonuclease
MKEKHDDM_00877	3.52e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MKEKHDDM_00879	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
MKEKHDDM_00880	4.02e-171	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MKEKHDDM_00881	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKEKHDDM_00882	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MKEKHDDM_00884	2.1e-289	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
MKEKHDDM_00885	1.42e-179	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKEKHDDM_00886	4.37e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_00887	7.73e-170	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_00888	6.64e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_00889	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKEKHDDM_00890	5.69e-235	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MKEKHDDM_00891	4.5e-180	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKEKHDDM_00892	1.23e-229	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MKEKHDDM_00893	8.27e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKEKHDDM_00894	8.61e-273	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MKEKHDDM_00895	1.38e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKEKHDDM_00896	5.25e-106	ygaO	-	-	-	-	-	-	-
MKEKHDDM_00898	1.3e-145	yhzB	-	-	S	-	-	-	B3/4 domain
MKEKHDDM_00899	2.08e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKEKHDDM_00900	6.09e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
MKEKHDDM_00901	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKEKHDDM_00902	1.39e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MKEKHDDM_00903	3.45e-86	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MKEKHDDM_00904	2.02e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MKEKHDDM_00905	1.23e-07	-	-	-	-	-	-	-	-
MKEKHDDM_00906	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MKEKHDDM_00907	1.77e-280	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MKEKHDDM_00908	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MKEKHDDM_00909	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MKEKHDDM_00910	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MKEKHDDM_00911	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MKEKHDDM_00912	1.41e-72	yhcC	-	-	-	-	-	-	-
MKEKHDDM_00913	1.16e-66	-	-	-	-	-	-	-	-
MKEKHDDM_00914	4.71e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_00915	1.78e-162	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00916	1.93e-214	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00917	1.29e-208	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKEKHDDM_00918	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MKEKHDDM_00919	1.44e-190	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MKEKHDDM_00920	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MKEKHDDM_00921	1.29e-293	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKEKHDDM_00922	1.66e-81	yhcM	-	-	-	-	-	-	-
MKEKHDDM_00923	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKEKHDDM_00924	3.2e-205	yhcP	-	-	-	-	-	-	-
MKEKHDDM_00925	1.81e-150	yhcQ	-	-	M	-	-	-	Spore coat protein
MKEKHDDM_00926	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKEKHDDM_00927	2.63e-136	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MKEKHDDM_00928	9.64e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MKEKHDDM_00929	6.3e-91	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MKEKHDDM_00930	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MKEKHDDM_00931	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MKEKHDDM_00932	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKEKHDDM_00933	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKEKHDDM_00934	5.16e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKEKHDDM_00935	9.46e-198	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MKEKHDDM_00936	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKEKHDDM_00937	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKEKHDDM_00938	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MKEKHDDM_00939	3.84e-28	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_00940	7.46e-141	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_00941	1.02e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MKEKHDDM_00942	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
MKEKHDDM_00943	6.94e-70	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MKEKHDDM_00944	1.41e-295	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKEKHDDM_00945	1.32e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MKEKHDDM_00946	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
MKEKHDDM_00947	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MKEKHDDM_00948	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MKEKHDDM_00949	2.8e-171	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKEKHDDM_00950	2.01e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_00951	6.67e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKEKHDDM_00952	4.53e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_00953	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MKEKHDDM_00954	2.07e-267	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKEKHDDM_00955	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MKEKHDDM_00956	5.66e-256	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MKEKHDDM_00957	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_00958	3.75e-141	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKEKHDDM_00959	3.94e-307	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKEKHDDM_00960	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MKEKHDDM_00961	7e-287	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MKEKHDDM_00962	1.35e-301	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKEKHDDM_00963	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKEKHDDM_00964	2.12e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKEKHDDM_00965	9.63e-77	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKEKHDDM_00966	1.28e-165	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKEKHDDM_00967	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MKEKHDDM_00968	6.68e-262	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MKEKHDDM_00969	9.8e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKEKHDDM_00970	1.7e-201	nodB1	-	-	G	-	-	-	deacetylase
MKEKHDDM_00971	9.8e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MKEKHDDM_00972	1.22e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_00973	2.67e-124	ymcC	-	-	S	-	-	-	Membrane
MKEKHDDM_00974	7.15e-110	-	-	-	T	-	-	-	universal stress protein
MKEKHDDM_00976	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKEKHDDM_00977	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKEKHDDM_00978	1.57e-141	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MKEKHDDM_00980	9.47e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MKEKHDDM_00981	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MKEKHDDM_00982	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MKEKHDDM_00983	5.37e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MKEKHDDM_00984	3.88e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MKEKHDDM_00985	9.47e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MKEKHDDM_00986	7.1e-258	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MKEKHDDM_00987	2.95e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MKEKHDDM_00988	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MKEKHDDM_00989	5.77e-316	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MKEKHDDM_00990	6.67e-265	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MKEKHDDM_00991	1.87e-113	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MKEKHDDM_00993	4.11e-175	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MKEKHDDM_00994	7.01e-20	-	-	-	S	-	-	-	YhzD-like protein
MKEKHDDM_00995	1.12e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_00996	1.13e-275	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MKEKHDDM_00997	1.24e-298	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MKEKHDDM_00998	0.0	yhaN	-	-	L	-	-	-	AAA domain
MKEKHDDM_00999	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MKEKHDDM_01000	2.02e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MKEKHDDM_01001	1.93e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKEKHDDM_01002	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MKEKHDDM_01003	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MKEKHDDM_01004	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MKEKHDDM_01005	2.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MKEKHDDM_01006	2.55e-24	-	-	-	-	-	-	-	-
MKEKHDDM_01007	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MKEKHDDM_01008	5.91e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKEKHDDM_01009	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MKEKHDDM_01010	5.22e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MKEKHDDM_01011	6.41e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MKEKHDDM_01012	3.02e-162	ecsC	-	-	S	-	-	-	EcsC protein family
MKEKHDDM_01013	9.88e-283	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKEKHDDM_01014	2.68e-309	yhfA	-	-	C	-	-	-	membrane
MKEKHDDM_01015	3.1e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MKEKHDDM_01016	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKEKHDDM_01017	8.58e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKEKHDDM_01018	4.49e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MKEKHDDM_01019	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKEKHDDM_01020	4.41e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01021	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MKEKHDDM_01022	5.68e-233	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKEKHDDM_01024	6.05e-250	yhfE	-	-	G	-	-	-	peptidase M42
MKEKHDDM_01025	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKEKHDDM_01027	6.93e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MKEKHDDM_01028	6.47e-242	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MKEKHDDM_01029	2.21e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
MKEKHDDM_01030	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MKEKHDDM_01031	2.38e-86	yhfM	-	-	-	-	-	-	-
MKEKHDDM_01032	1.11e-301	yhfN	-	-	O	-	-	-	Peptidase M48
MKEKHDDM_01033	3.46e-265	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKEKHDDM_01034	1.51e-200	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MKEKHDDM_01035	6.03e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MKEKHDDM_01036	3.68e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MKEKHDDM_01037	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MKEKHDDM_01038	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MKEKHDDM_01039	1.08e-274	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MKEKHDDM_01040	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MKEKHDDM_01041	5.51e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_01042	5.7e-44	yhzC	-	-	S	-	-	-	IDEAL
MKEKHDDM_01043	8.93e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MKEKHDDM_01044	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MKEKHDDM_01045	9.56e-89	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MKEKHDDM_01046	1.41e-119	-	-	-	S	-	-	-	MepB protein
MKEKHDDM_01047	3.65e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MKEKHDDM_01048	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MKEKHDDM_01049	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
MKEKHDDM_01050	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKEKHDDM_01051	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MKEKHDDM_01052	2.39e-78	yhjD	-	-	-	-	-	-	-
MKEKHDDM_01053	1.91e-143	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MKEKHDDM_01054	9.51e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKEKHDDM_01055	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MKEKHDDM_01056	1.7e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_01057	1.7e-262	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MKEKHDDM_01058	9.23e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_01059	2.72e-142	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MKEKHDDM_01060	5.98e-121	yhjR	-	-	S	-	-	-	Rubrerythrin
MKEKHDDM_01061	3.25e-105	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKEKHDDM_01062	1.03e-38	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKEKHDDM_01063	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MKEKHDDM_01064	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MKEKHDDM_01065	1.35e-282	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKEKHDDM_01066	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MKEKHDDM_01067	1.53e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MKEKHDDM_01068	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MKEKHDDM_01069	1.61e-84	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MKEKHDDM_01070	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MKEKHDDM_01071	3.46e-108	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MKEKHDDM_01072	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MKEKHDDM_01073	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MKEKHDDM_01074	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MKEKHDDM_01075	1.54e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MKEKHDDM_01076	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
MKEKHDDM_01077	1.59e-125	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MKEKHDDM_01078	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKEKHDDM_01079	6.59e-172	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MKEKHDDM_01080	1.84e-311	yisQ	-	-	V	-	-	-	Mate efflux family protein
MKEKHDDM_01081	9.14e-204	yisR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_01082	3.11e-116	yisT	-	-	S	-	-	-	DinB family
MKEKHDDM_01083	1.2e-95	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MKEKHDDM_01084	1.45e-240	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKEKHDDM_01085	6.14e-108	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MKEKHDDM_01086	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_01087	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKEKHDDM_01088	6.39e-79	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MKEKHDDM_01089	2.25e-206	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MKEKHDDM_01090	1.26e-220	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
MKEKHDDM_01091	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MKEKHDDM_01092	5.74e-304	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MKEKHDDM_01094	5.28e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01095	1.61e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_01096	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MKEKHDDM_01097	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MKEKHDDM_01098	1.49e-11	-	-	-	-	-	-	-	-
MKEKHDDM_01099	2.16e-198	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MKEKHDDM_01100	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKEKHDDM_01101	1.33e-67	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MKEKHDDM_01102	9.25e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MKEKHDDM_01103	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MKEKHDDM_01104	5.08e-83	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MKEKHDDM_01105	1.01e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKEKHDDM_01106	5.39e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKEKHDDM_01107	8.95e-176	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MKEKHDDM_01108	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MKEKHDDM_01109	2.41e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKEKHDDM_01110	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MKEKHDDM_01111	2.89e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKEKHDDM_01112	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MKEKHDDM_01113	1.06e-32	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MKEKHDDM_01114	8.36e-174	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MKEKHDDM_01115	9.68e-134	yjaV	-	-	-	-	-	-	-
MKEKHDDM_01116	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MKEKHDDM_01117	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MKEKHDDM_01118	2.82e-44	yjzB	-	-	-	-	-	-	-
MKEKHDDM_01119	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKEKHDDM_01120	5.48e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKEKHDDM_01121	1.84e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MKEKHDDM_01122	4.15e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01123	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01124	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKEKHDDM_01125	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01126	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01127	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MKEKHDDM_01128	1.45e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MKEKHDDM_01129	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKEKHDDM_01130	2.53e-213	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01131	7.23e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01132	8.69e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01133	2.19e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01134	3e-296	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MKEKHDDM_01135	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKEKHDDM_01136	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKEKHDDM_01137	2.77e-141	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MKEKHDDM_01138	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKEKHDDM_01139	4.01e-282	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MKEKHDDM_01140	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MKEKHDDM_01141	3.14e-27	-	-	-	-	-	-	-	-
MKEKHDDM_01142	2.46e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKEKHDDM_01143	7.06e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MKEKHDDM_01144	7.66e-153	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKEKHDDM_01145	2.86e-127	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01146	1e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MKEKHDDM_01147	9.01e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MKEKHDDM_01148	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKEKHDDM_01149	1.65e-211	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MKEKHDDM_01150	6.41e-185	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MKEKHDDM_01151	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKEKHDDM_01152	8.1e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKEKHDDM_01153	2.32e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MKEKHDDM_01154	8.47e-264	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MKEKHDDM_01155	4.53e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
MKEKHDDM_01156	7.36e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKEKHDDM_01157	6.18e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKEKHDDM_01158	6.11e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKEKHDDM_01159	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MKEKHDDM_01160	1.95e-124	yjbX	-	-	S	-	-	-	Spore coat protein
MKEKHDDM_01161	1.12e-103	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MKEKHDDM_01162	1.61e-116	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MKEKHDDM_01163	1.11e-101	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MKEKHDDM_01164	8.38e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
MKEKHDDM_01165	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MKEKHDDM_01166	2.05e-73	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MKEKHDDM_01169	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKEKHDDM_01170	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MKEKHDDM_01171	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKEKHDDM_01172	6.07e-49	-	-	-	-	-	-	-	-
MKEKHDDM_01173	2.99e-162	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MKEKHDDM_01174	1.53e-158	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_01175	2.48e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MKEKHDDM_01176	1.76e-47	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MKEKHDDM_01178	1.05e-97	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKEKHDDM_01179	2e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MKEKHDDM_01180	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MKEKHDDM_01181	1.41e-266	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKEKHDDM_01182	1.34e-278	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKEKHDDM_01184	2.49e-218	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MKEKHDDM_01187	5.77e-47	-	-	-	-	-	-	-	-
MKEKHDDM_01188	3.4e-49	-	-	-	-	-	-	-	-
MKEKHDDM_01191	1.66e-39	-	-	-	S	-	-	-	BhlA holin family
MKEKHDDM_01192	8.2e-185	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKEKHDDM_01193	7.35e-46	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
MKEKHDDM_01195	3.11e-46	-	-	-	-	-	-	-	-
MKEKHDDM_01196	2.38e-05	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MKEKHDDM_01197	2.03e-73	-	-	-	-	-	-	-	-
MKEKHDDM_01198	0.0	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MKEKHDDM_01199	1.32e-119	-	-	-	-	-	-	-	-
MKEKHDDM_01202	8.05e-166	-	-	-	-	-	-	-	-
MKEKHDDM_01204	2.12e-104	-	-	-	S	-	-	-	Alpha beta hydrolase
MKEKHDDM_01205	7.44e-66	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MKEKHDDM_01206	8.95e-94	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
MKEKHDDM_01208	8.5e-213	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MKEKHDDM_01209	2.2e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MKEKHDDM_01210	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MKEKHDDM_01211	3.68e-107	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_01212	1.14e-282	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MKEKHDDM_01213	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MKEKHDDM_01214	1.21e-241	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKEKHDDM_01215	4.47e-276	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKEKHDDM_01216	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKEKHDDM_01217	2.56e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_01218	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKEKHDDM_01219	5.89e-179	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKEKHDDM_01220	3.55e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MKEKHDDM_01222	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MKEKHDDM_01224	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
MKEKHDDM_01225	6.26e-92	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MKEKHDDM_01226	3.5e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MKEKHDDM_01227	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MKEKHDDM_01228	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKEKHDDM_01229	1.09e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKEKHDDM_01230	4.38e-286	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKEKHDDM_01231	1.73e-40	-	-	-	-	-	-	-	-
MKEKHDDM_01232	7.93e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKEKHDDM_01233	2.42e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MKEKHDDM_01234	1.08e-166	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01235	5.01e-228	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MKEKHDDM_01236	2.1e-119	yjlB	-	-	S	-	-	-	Cupin domain
MKEKHDDM_01237	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKEKHDDM_01238	6.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKEKHDDM_01239	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MKEKHDDM_01240	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MKEKHDDM_01241	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MKEKHDDM_01242	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MKEKHDDM_01243	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MKEKHDDM_01244	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKEKHDDM_01245	1.02e-103	yjoA	-	-	S	-	-	-	DinB family
MKEKHDDM_01246	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_01248	2.37e-221	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKEKHDDM_01249	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
MKEKHDDM_01250	8.47e-141	yjqB	-	-	S	-	-	-	phage-related replication protein
MKEKHDDM_01251	9.32e-188	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MKEKHDDM_01252	6.51e-145	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MKEKHDDM_01253	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKEKHDDM_01255	7.52e-197	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MKEKHDDM_01259	1.07e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKEKHDDM_01260	4.8e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MKEKHDDM_01261	2.75e-262	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MKEKHDDM_01262	7.34e-304	xkdE3	-	-	S	-	-	-	portal protein
MKEKHDDM_01263	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MKEKHDDM_01264	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
MKEKHDDM_01265	1.78e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MKEKHDDM_01266	5.78e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MKEKHDDM_01267	2.07e-78	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MKEKHDDM_01268	4.28e-74	xkdJ	-	-	-	-	-	-	-
MKEKHDDM_01269	1.57e-20	-	-	-	-	-	-	-	-
MKEKHDDM_01270	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MKEKHDDM_01271	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MKEKHDDM_01272	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MKEKHDDM_01273	4.33e-27	-	-	-	-	-	-	-	-
MKEKHDDM_01274	1.4e-275	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MKEKHDDM_01275	1.88e-144	xkdP	-	-	S	-	-	-	Lysin motif
MKEKHDDM_01276	1.87e-206	xkdQ	-	-	G	-	-	-	NLP P60 protein
MKEKHDDM_01277	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MKEKHDDM_01278	2.86e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MKEKHDDM_01279	7.58e-213	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKEKHDDM_01280	2.48e-113	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MKEKHDDM_01281	3.63e-37	-	-	-	-	-	-	-	-
MKEKHDDM_01282	1.19e-84	-	-	-	-	-	-	-	-
MKEKHDDM_01284	5.6e-41	xkdX	-	-	-	-	-	-	-
MKEKHDDM_01285	4.28e-176	xepA	-	-	-	-	-	-	-
MKEKHDDM_01286	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MKEKHDDM_01287	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MKEKHDDM_01288	5.16e-217	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MKEKHDDM_01289	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MKEKHDDM_01290	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MKEKHDDM_01291	7.07e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MKEKHDDM_01292	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MKEKHDDM_01293	2.3e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MKEKHDDM_01294	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKEKHDDM_01295	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKEKHDDM_01296	1.56e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKEKHDDM_01298	1.85e-276	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKEKHDDM_01299	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MKEKHDDM_01301	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MKEKHDDM_01302	1.39e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01303	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKEKHDDM_01304	2.26e-243	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01305	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKEKHDDM_01306	1.14e-225	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MKEKHDDM_01307	1.06e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKEKHDDM_01308	1.6e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKEKHDDM_01309	2.31e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_01310	5.93e-263	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MKEKHDDM_01311	1.99e-202	ykgA	-	-	E	-	-	-	Amidinotransferase
MKEKHDDM_01312	8.79e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MKEKHDDM_01313	1.82e-130	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKEKHDDM_01314	4.09e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKEKHDDM_01315	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKEKHDDM_01316	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MKEKHDDM_01317	1.07e-262	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKEKHDDM_01318	1.87e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKEKHDDM_01319	3.98e-92	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MKEKHDDM_01320	1.2e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MKEKHDDM_01321	5.52e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MKEKHDDM_01322	3.86e-81	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MKEKHDDM_01324	2.48e-275	-	-	-	M	-	-	-	Glycosyl transferase family 2
MKEKHDDM_01325	1.35e-185	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
MKEKHDDM_01326	3.41e-278	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_01327	7.47e-154	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MKEKHDDM_01328	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKEKHDDM_01329	1.74e-224	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKEKHDDM_01330	4.46e-190	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKEKHDDM_01331	1.32e-170	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MKEKHDDM_01332	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_01333	2.31e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MKEKHDDM_01334	3.11e-310	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MKEKHDDM_01336	8.66e-310	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MKEKHDDM_01337	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
MKEKHDDM_01338	1.11e-23	-	-	-	-	-	-	-	-
MKEKHDDM_01339	5.25e-37	ykoL	-	-	-	-	-	-	-
MKEKHDDM_01340	5.46e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MKEKHDDM_01341	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MKEKHDDM_01342	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MKEKHDDM_01343	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKEKHDDM_01344	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
MKEKHDDM_01345	9.72e-172	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKEKHDDM_01346	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_01347	2.53e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MKEKHDDM_01348	2.33e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MKEKHDDM_01349	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MKEKHDDM_01350	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MKEKHDDM_01351	1.8e-306	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MKEKHDDM_01352	1.73e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKEKHDDM_01353	3.07e-32	ykzE	-	-	-	-	-	-	-
MKEKHDDM_01354	1.36e-243	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MKEKHDDM_01355	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_01356	1.53e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKEKHDDM_01358	4.44e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MKEKHDDM_01359	1.65e-285	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MKEKHDDM_01360	6.67e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKEKHDDM_01361	4.42e-292	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MKEKHDDM_01362	2.73e-289	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MKEKHDDM_01363	3.86e-174	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MKEKHDDM_01364	6.42e-147	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MKEKHDDM_01365	2.6e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MKEKHDDM_01367	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKEKHDDM_01368	1.36e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MKEKHDDM_01369	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MKEKHDDM_01370	2.96e-176	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MKEKHDDM_01371	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MKEKHDDM_01372	2.69e-232	ykvI	-	-	S	-	-	-	membrane
MKEKHDDM_01373	1.38e-255	-	-	-	-	-	-	-	-
MKEKHDDM_01374	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKEKHDDM_01375	8.23e-106	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MKEKHDDM_01376	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MKEKHDDM_01377	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKEKHDDM_01378	1e-79	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKEKHDDM_01379	1.05e-169	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKEKHDDM_01380	5.71e-42	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKEKHDDM_01381	2.88e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKEKHDDM_01382	1.47e-45	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
MKEKHDDM_01383	1.44e-203	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MKEKHDDM_01385	1.17e-56	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MKEKHDDM_01386	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01387	4.16e-38	-	-	-	-	-	-	-	-
MKEKHDDM_01388	5.92e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MKEKHDDM_01389	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_01390	2.1e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
MKEKHDDM_01391	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKEKHDDM_01392	4.04e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKEKHDDM_01394	1.01e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_01395	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MKEKHDDM_01396	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_01397	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MKEKHDDM_01398	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKEKHDDM_01399	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01400	1.68e-254	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MKEKHDDM_01401	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKEKHDDM_01402	3.3e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKEKHDDM_01403	2.78e-160	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MKEKHDDM_01404	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MKEKHDDM_01405	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_01406	1.62e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MKEKHDDM_01407	6.38e-15	-	-	-	-	-	-	-	-
MKEKHDDM_01408	1.93e-213	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MKEKHDDM_01409	6.09e-70	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
MKEKHDDM_01410	1.16e-62	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
MKEKHDDM_01411	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
MKEKHDDM_01412	7.96e-309	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_01413	8.88e-117	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01414	6.6e-200	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MKEKHDDM_01415	2.13e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_01417	3.14e-296	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MKEKHDDM_01418	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01419	4.35e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MKEKHDDM_01420	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MKEKHDDM_01421	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
MKEKHDDM_01422	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_01423	3.15e-117	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MKEKHDDM_01424	1.42e-212	ykuO	-	-	-	-	-	-	-
MKEKHDDM_01425	5.1e-102	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MKEKHDDM_01426	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKEKHDDM_01427	2.39e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKEKHDDM_01428	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MKEKHDDM_01429	2.1e-179	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MKEKHDDM_01430	4.7e-103	ykuV	-	-	CO	-	-	-	thiol-disulfide
MKEKHDDM_01431	7.46e-127	rok	-	-	K	-	-	-	Repressor of ComK
MKEKHDDM_01432	2.53e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
MKEKHDDM_01433	9.94e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MKEKHDDM_01434	1.71e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKEKHDDM_01435	5.6e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MKEKHDDM_01436	2.64e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MKEKHDDM_01437	2.92e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MKEKHDDM_01438	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKEKHDDM_01439	4.64e-140	yknW	-	-	S	-	-	-	Yip1 domain
MKEKHDDM_01440	2e-246	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKEKHDDM_01441	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_01442	7.01e-268	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MKEKHDDM_01443	6.81e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01444	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MKEKHDDM_01445	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKEKHDDM_01446	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKEKHDDM_01447	3.68e-50	ykoA	-	-	-	-	-	-	-
MKEKHDDM_01448	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKEKHDDM_01449	1.71e-211	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKEKHDDM_01450	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MKEKHDDM_01451	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MKEKHDDM_01452	3.72e-235	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MKEKHDDM_01453	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MKEKHDDM_01454	5.87e-313	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKEKHDDM_01455	5.27e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MKEKHDDM_01456	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKEKHDDM_01457	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKEKHDDM_01458	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKEKHDDM_01459	1.28e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MKEKHDDM_01460	2.61e-188	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKEKHDDM_01461	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKEKHDDM_01462	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKEKHDDM_01463	5.6e-134	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MKEKHDDM_01464	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_01465	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01466	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MKEKHDDM_01467	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01468	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01469	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01470	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01471	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01472	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MKEKHDDM_01473	3.48e-269	-	-	-	V	-	-	-	Beta-lactamase
MKEKHDDM_01474	7.79e-261	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKEKHDDM_01475	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKEKHDDM_01476	8.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKEKHDDM_01477	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKEKHDDM_01478	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MKEKHDDM_01479	1.63e-191	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKEKHDDM_01480	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MKEKHDDM_01481	1.9e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MKEKHDDM_01482	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MKEKHDDM_01483	7.89e-32	ykzI	-	-	-	-	-	-	-
MKEKHDDM_01484	8.12e-196	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MKEKHDDM_01485	1.3e-108	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MKEKHDDM_01486	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MKEKHDDM_01487	4.16e-236	ylaA	-	-	-	-	-	-	-
MKEKHDDM_01488	7.37e-59	ylaB	-	-	-	-	-	-	-
MKEKHDDM_01489	1.81e-72	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_01491	6.54e-61	ylaE	-	-	-	-	-	-	-
MKEKHDDM_01492	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MKEKHDDM_01493	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MKEKHDDM_01494	2.85e-64	-	-	-	S	-	-	-	YlaH-like protein
MKEKHDDM_01495	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01496	3.84e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKEKHDDM_01497	9.42e-314	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MKEKHDDM_01498	4.13e-109	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKEKHDDM_01499	6.57e-224	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MKEKHDDM_01500	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MKEKHDDM_01501	3.49e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKEKHDDM_01502	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKEKHDDM_01503	1.16e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MKEKHDDM_01504	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKEKHDDM_01505	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MKEKHDDM_01506	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKEKHDDM_01507	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MKEKHDDM_01508	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MKEKHDDM_01509	2.53e-212	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MKEKHDDM_01510	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
MKEKHDDM_01511	3.91e-95	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MKEKHDDM_01512	2.8e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MKEKHDDM_01513	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
MKEKHDDM_01514	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MKEKHDDM_01515	9.54e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MKEKHDDM_01516	2.78e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
MKEKHDDM_01517	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MKEKHDDM_01518	1.01e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKEKHDDM_01519	2.91e-277	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MKEKHDDM_01520	1.23e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKEKHDDM_01521	3.07e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MKEKHDDM_01522	2.13e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MKEKHDDM_01523	4.88e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MKEKHDDM_01524	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MKEKHDDM_01525	3.13e-111	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MKEKHDDM_01526	3.26e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
MKEKHDDM_01527	8.18e-210	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKEKHDDM_01528	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKEKHDDM_01529	1.78e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MKEKHDDM_01530	4.08e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKEKHDDM_01531	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MKEKHDDM_01532	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MKEKHDDM_01533	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MKEKHDDM_01534	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKEKHDDM_01535	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKEKHDDM_01536	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKEKHDDM_01537	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKEKHDDM_01538	1.15e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKEKHDDM_01539	9.58e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MKEKHDDM_01540	2.2e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKEKHDDM_01541	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKEKHDDM_01542	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKEKHDDM_01543	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MKEKHDDM_01544	1.94e-216	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MKEKHDDM_01545	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_01546	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_01547	1.33e-185	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MKEKHDDM_01548	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MKEKHDDM_01549	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
MKEKHDDM_01550	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MKEKHDDM_01551	1.5e-160	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKEKHDDM_01552	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKEKHDDM_01553	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MKEKHDDM_01554	3.54e-181	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MKEKHDDM_01555	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MKEKHDDM_01556	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKEKHDDM_01557	8.52e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MKEKHDDM_01558	1.24e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKEKHDDM_01559	1.26e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MKEKHDDM_01560	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKEKHDDM_01561	1.39e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MKEKHDDM_01562	1.47e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MKEKHDDM_01563	7.77e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKEKHDDM_01564	3.09e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKEKHDDM_01565	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MKEKHDDM_01566	1.01e-180	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MKEKHDDM_01567	7.36e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKEKHDDM_01568	5.2e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKEKHDDM_01569	4.44e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKEKHDDM_01571	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MKEKHDDM_01572	8.54e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MKEKHDDM_01573	3.72e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MKEKHDDM_01574	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MKEKHDDM_01575	6.89e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKEKHDDM_01576	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MKEKHDDM_01577	6.27e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MKEKHDDM_01578	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MKEKHDDM_01579	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MKEKHDDM_01580	1.51e-198	yloC	-	-	S	-	-	-	stress-induced protein
MKEKHDDM_01581	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MKEKHDDM_01582	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MKEKHDDM_01583	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKEKHDDM_01584	2.18e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKEKHDDM_01585	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKEKHDDM_01586	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKEKHDDM_01587	7.57e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKEKHDDM_01588	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKEKHDDM_01589	8.79e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKEKHDDM_01590	2.88e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MKEKHDDM_01591	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKEKHDDM_01592	1.78e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKEKHDDM_01593	3.42e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MKEKHDDM_01594	2.61e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MKEKHDDM_01595	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MKEKHDDM_01596	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_01597	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MKEKHDDM_01598	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKEKHDDM_01599	4.14e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKEKHDDM_01600	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKEKHDDM_01601	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MKEKHDDM_01602	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKEKHDDM_01603	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_01604	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MKEKHDDM_01605	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKEKHDDM_01606	6.09e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKEKHDDM_01607	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MKEKHDDM_01608	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKEKHDDM_01609	3.54e-181	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MKEKHDDM_01610	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKEKHDDM_01611	3.46e-302	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKEKHDDM_01612	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MKEKHDDM_01613	1.41e-48	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MKEKHDDM_01614	5.66e-79	ylqD	-	-	S	-	-	-	YlqD protein
MKEKHDDM_01615	1.45e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKEKHDDM_01616	9.8e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MKEKHDDM_01617	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKEKHDDM_01618	7.24e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKEKHDDM_01619	3.94e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKEKHDDM_01620	0.0	ylqG	-	-	-	-	-	-	-
MKEKHDDM_01621	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MKEKHDDM_01622	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKEKHDDM_01623	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKEKHDDM_01624	3.11e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MKEKHDDM_01625	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKEKHDDM_01626	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKEKHDDM_01627	3.64e-219	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MKEKHDDM_01628	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKEKHDDM_01629	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKEKHDDM_01630	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKEKHDDM_01631	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MKEKHDDM_01632	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MKEKHDDM_01633	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MKEKHDDM_01634	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MKEKHDDM_01635	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKEKHDDM_01636	1.32e-120	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MKEKHDDM_01637	1.74e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MKEKHDDM_01638	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MKEKHDDM_01639	1.98e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MKEKHDDM_01640	2.86e-258	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MKEKHDDM_01641	2.55e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MKEKHDDM_01642	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MKEKHDDM_01643	7.7e-80	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MKEKHDDM_01644	8.99e-229	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKEKHDDM_01645	1.21e-247	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKEKHDDM_01646	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MKEKHDDM_01647	2.2e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MKEKHDDM_01648	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MKEKHDDM_01649	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MKEKHDDM_01650	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MKEKHDDM_01651	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKEKHDDM_01652	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKEKHDDM_01653	2.65e-248	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MKEKHDDM_01654	1.49e-198	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MKEKHDDM_01655	2.02e-248	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MKEKHDDM_01656	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MKEKHDDM_01657	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MKEKHDDM_01658	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MKEKHDDM_01659	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MKEKHDDM_01660	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_01661	1.44e-94	ylxL	-	-	-	-	-	-	-
MKEKHDDM_01662	2.47e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MKEKHDDM_01663	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKEKHDDM_01664	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MKEKHDDM_01665	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKEKHDDM_01666	7.76e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKEKHDDM_01667	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MKEKHDDM_01668	2.2e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKEKHDDM_01669	1.15e-296	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MKEKHDDM_01670	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKEKHDDM_01671	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKEKHDDM_01672	5.66e-106	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MKEKHDDM_01673	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MKEKHDDM_01674	4.58e-54	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MKEKHDDM_01675	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MKEKHDDM_01676	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKEKHDDM_01677	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MKEKHDDM_01678	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKEKHDDM_01679	2.11e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKEKHDDM_01680	2.6e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MKEKHDDM_01681	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKEKHDDM_01682	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKEKHDDM_01683	1.02e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MKEKHDDM_01684	2.51e-300	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MKEKHDDM_01685	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MKEKHDDM_01686	8.13e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MKEKHDDM_01687	4.75e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MKEKHDDM_01688	4.97e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKEKHDDM_01689	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKEKHDDM_01690	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKEKHDDM_01691	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKEKHDDM_01692	1.31e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MKEKHDDM_01693	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
MKEKHDDM_01694	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKEKHDDM_01695	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01696	3.16e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_01697	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_01698	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MKEKHDDM_01699	3.22e-306	albE	-	-	S	-	-	-	Peptidase M16
MKEKHDDM_01700	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
MKEKHDDM_01701	1.43e-164	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MKEKHDDM_01702	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MKEKHDDM_01703	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MKEKHDDM_01704	1.17e-178	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MKEKHDDM_01705	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKEKHDDM_01706	3.27e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MKEKHDDM_01707	3.42e-236	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKEKHDDM_01708	5.46e-279	pbpX	-	-	V	-	-	-	Beta-lactamase
MKEKHDDM_01709	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MKEKHDDM_01710	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MKEKHDDM_01711	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MKEKHDDM_01712	6.82e-250	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MKEKHDDM_01713	4.29e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKEKHDDM_01714	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKEKHDDM_01715	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MKEKHDDM_01716	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MKEKHDDM_01717	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKEKHDDM_01718	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKEKHDDM_01719	2.34e-88	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKEKHDDM_01720	3.97e-49	-	-	-	-	-	-	-	-
MKEKHDDM_01723	4.05e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MKEKHDDM_01724	4.05e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_01725	4.5e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MKEKHDDM_01726	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_01727	2.51e-47	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MKEKHDDM_01728	3.63e-309	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MKEKHDDM_01729	4.33e-187	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MKEKHDDM_01730	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MKEKHDDM_01731	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MKEKHDDM_01732	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01733	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_01734	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MKEKHDDM_01735	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MKEKHDDM_01736	1.13e-292	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKEKHDDM_01737	1.81e-103	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MKEKHDDM_01738	1.28e-152	yoaK	-	-	S	-	-	-	Membrane
MKEKHDDM_01739	2.78e-82	ymzB	-	-	-	-	-	-	-
MKEKHDDM_01740	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MKEKHDDM_01741	3.03e-06	-	-	-	-	-	-	-	-
MKEKHDDM_01742	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
MKEKHDDM_01743	1.41e-103	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MKEKHDDM_01744	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKEKHDDM_01745	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKEKHDDM_01747	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
MKEKHDDM_01748	7.63e-221	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKEKHDDM_01749	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MKEKHDDM_01750	9.98e-58	-	-	-	-	-	-	-	-
MKEKHDDM_01751	9.42e-29	ymzA	-	-	-	-	-	-	-
MKEKHDDM_01752	9.34e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MKEKHDDM_01753	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_01754	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_01755	3.18e-141	ymaB	-	-	S	-	-	-	MutT family
MKEKHDDM_01756	1.07e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKEKHDDM_01757	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MKEKHDDM_01758	5.44e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKEKHDDM_01759	4.1e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MKEKHDDM_01760	5.34e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MKEKHDDM_01761	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MKEKHDDM_01763	8.75e-42	-	-	-	-	-	-	-	-
MKEKHDDM_01764	5.15e-117	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MKEKHDDM_01765	1.55e-282	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MKEKHDDM_01766	6.11e-65	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MKEKHDDM_01767	2.28e-85	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MKEKHDDM_01768	1.31e-269	mrjp	-	-	G	-	-	-	Major royal jelly protein
MKEKHDDM_01769	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MKEKHDDM_01770	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKEKHDDM_01771	7.75e-279	xylR	-	-	GK	-	-	-	ROK family
MKEKHDDM_01772	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MKEKHDDM_01773	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MKEKHDDM_01774	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MKEKHDDM_01777	2.21e-27	-	-	-	-	-	-	-	-
MKEKHDDM_01778	1.2e-72	dinB	-	-	S	-	-	-	DinB family
MKEKHDDM_01779	5.08e-238	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MKEKHDDM_01780	1.14e-10	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MKEKHDDM_01781	6.73e-23	-	-	-	-	-	-	-	-
MKEKHDDM_01782	2.86e-26	yoaW	-	-	-	-	-	-	-
MKEKHDDM_01783	4.33e-05	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MKEKHDDM_01784	6.56e-181	yoaP	-	-	K	-	-	-	YoaP-like
MKEKHDDM_01785	3.94e-103	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_01786	2.01e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MKEKHDDM_01787	4.85e-257	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_01788	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
MKEKHDDM_01789	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKEKHDDM_01790	7.48e-85	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKEKHDDM_01791	4.49e-125	yvgO	-	-	-	-	-	-	-
MKEKHDDM_01793	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MKEKHDDM_01794	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MKEKHDDM_01795	1.67e-183	yndL	-	-	S	-	-	-	Replication protein
MKEKHDDM_01796	1.74e-11	-	-	-	-	-	-	-	-
MKEKHDDM_01797	6.29e-185	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MKEKHDDM_01798	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKEKHDDM_01800	3.18e-141	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKEKHDDM_01801	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MKEKHDDM_01802	5.22e-145	yneB	-	-	L	-	-	-	resolvase
MKEKHDDM_01803	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MKEKHDDM_01804	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKEKHDDM_01805	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MKEKHDDM_01806	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MKEKHDDM_01807	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MKEKHDDM_01808	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MKEKHDDM_01809	7.09e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MKEKHDDM_01810	2.27e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MKEKHDDM_01811	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MKEKHDDM_01812	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MKEKHDDM_01813	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MKEKHDDM_01814	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MKEKHDDM_01815	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKEKHDDM_01816	3.46e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKEKHDDM_01818	1e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MKEKHDDM_01819	1.7e-96	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MKEKHDDM_01820	7.79e-70	yneQ	-	-	-	-	-	-	-
MKEKHDDM_01821	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MKEKHDDM_01822	9.09e-121	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKEKHDDM_01823	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MKEKHDDM_01824	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKEKHDDM_01825	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKEKHDDM_01826	3.14e-19	-	-	-	-	-	-	-	-
MKEKHDDM_01827	1.82e-63	ynfC	-	-	-	-	-	-	-
MKEKHDDM_01828	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MKEKHDDM_01829	2.13e-229	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MKEKHDDM_01830	4.91e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MKEKHDDM_01831	1.84e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MKEKHDDM_01832	7.99e-271	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MKEKHDDM_01833	7.45e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_01834	2.14e-232	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MKEKHDDM_01835	1.31e-285	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
MKEKHDDM_01836	5.72e-199	yndG	-	-	S	-	-	-	DoxX-like family
MKEKHDDM_01837	2.86e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MKEKHDDM_01838	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MKEKHDDM_01840	2.99e-34	-	-	-	-	-	-	-	-
MKEKHDDM_01842	1.3e-173	-	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKEKHDDM_01847	4.17e-89	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	Protein of unknown function (DUF1430)
MKEKHDDM_01848	4.96e-83	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKEKHDDM_01851	1.42e-114	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
MKEKHDDM_01852	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MKEKHDDM_01853	1.48e-69	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
MKEKHDDM_01854	9.79e-312	-	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_01855	1.32e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MKEKHDDM_01856	4.91e-316	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MKEKHDDM_01857	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKEKHDDM_01858	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01859	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01860	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01861	6.93e-281	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_01862	1.6e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKEKHDDM_01863	4.5e-157	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKEKHDDM_01864	8.91e-162	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKEKHDDM_01865	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MKEKHDDM_01866	1.52e-283	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKEKHDDM_01867	1.12e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MKEKHDDM_01868	2.6e-167	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKEKHDDM_01869	4.12e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKEKHDDM_01870	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MKEKHDDM_01871	8.08e-187	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MKEKHDDM_01872	2.26e-95	yngA	-	-	S	-	-	-	membrane
MKEKHDDM_01873	8.78e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKEKHDDM_01874	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MKEKHDDM_01875	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKEKHDDM_01876	4.99e-178	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MKEKHDDM_01877	1.48e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MKEKHDDM_01878	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MKEKHDDM_01879	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MKEKHDDM_01880	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKEKHDDM_01881	5.98e-265	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKEKHDDM_01882	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MKEKHDDM_01883	1.67e-85	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MKEKHDDM_01884	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
MKEKHDDM_01885	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01886	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01887	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01888	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01889	7.57e-179	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01890	4.81e-170	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01891	3.5e-59	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01892	5.72e-76	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01893	3.3e-132	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01894	3.33e-139	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01895	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01896	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_01897	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKEKHDDM_01898	1.93e-239	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MKEKHDDM_01899	3.69e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
MKEKHDDM_01900	4.47e-126	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MKEKHDDM_01902	3.97e-125	-	-	-	L	-	-	-	Integrase
MKEKHDDM_01903	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MKEKHDDM_01904	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MKEKHDDM_01905	1.6e-254	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
MKEKHDDM_01906	3.29e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MKEKHDDM_01907	3.78e-16	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKEKHDDM_01908	4.32e-200	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01909	3.07e-240	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MKEKHDDM_01910	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKEKHDDM_01911	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MKEKHDDM_01912	3.04e-204	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01913	3.29e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKEKHDDM_01914	2.93e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKEKHDDM_01915	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MKEKHDDM_01916	3.49e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_01917	6.9e-56	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKEKHDDM_01918	9.01e-178	yoxB	-	-	-	-	-	-	-
MKEKHDDM_01919	7.72e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MKEKHDDM_01920	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MKEKHDDM_01921	2.19e-248	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKEKHDDM_01922	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKEKHDDM_01924	4e-129	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_01925	1.15e-57	-	-	-	-	-	-	-	-
MKEKHDDM_01926	1.15e-113	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MKEKHDDM_01927	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MKEKHDDM_01928	2.12e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MKEKHDDM_01929	3.17e-174	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKEKHDDM_01930	1.86e-122	yobS	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_01931	1.1e-171	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKEKHDDM_01932	2.72e-119	yobW	-	-	-	-	-	-	-
MKEKHDDM_01933	7.69e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MKEKHDDM_01934	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKEKHDDM_01935	1.33e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MKEKHDDM_01936	2.04e-180	-	-	-	J	-	-	-	Protein required for attachment to host cells
MKEKHDDM_01937	1.87e-122	yocC	-	-	-	-	-	-	-
MKEKHDDM_01938	1.11e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MKEKHDDM_01940	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MKEKHDDM_01941	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKEKHDDM_01942	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKEKHDDM_01944	3.69e-78	yocK	-	-	T	-	-	-	general stress protein
MKEKHDDM_01945	1.69e-14	yocL	-	-	-	-	-	-	-
MKEKHDDM_01946	3.51e-13	yocN	-	-	-	-	-	-	-
MKEKHDDM_01947	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKEKHDDM_01948	9.63e-60	yozN	-	-	-	-	-	-	-
MKEKHDDM_01949	6.36e-50	yocN	-	-	-	-	-	-	-
MKEKHDDM_01950	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
MKEKHDDM_01952	4.69e-43	yozC	-	-	-	-	-	-	-
MKEKHDDM_01953	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKEKHDDM_01954	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MKEKHDDM_01955	4.76e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MKEKHDDM_01956	1.45e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKEKHDDM_01957	9.85e-215	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MKEKHDDM_01958	5.46e-181	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKEKHDDM_01959	2.47e-261	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MKEKHDDM_01960	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MKEKHDDM_01961	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MKEKHDDM_01962	3.45e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MKEKHDDM_01963	2.65e-144	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKEKHDDM_01964	6.08e-293	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKEKHDDM_01965	2.01e-286	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MKEKHDDM_01966	9.47e-144	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKEKHDDM_01968	4.62e-308	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MKEKHDDM_01969	1.44e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKEKHDDM_01970	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MKEKHDDM_01971	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MKEKHDDM_01972	1.05e-30	-	-	-	-	-	-	-	-
MKEKHDDM_01973	8.49e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MKEKHDDM_01974	1.15e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MKEKHDDM_01976	2.59e-89	iolK	-	-	S	-	-	-	tautomerase
MKEKHDDM_01977	1.08e-89	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MKEKHDDM_01978	2e-73	yodB	-	-	K	-	-	-	transcriptional
MKEKHDDM_01979	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
MKEKHDDM_01980	4.37e-143	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MKEKHDDM_01981	8.57e-219	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKEKHDDM_01982	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MKEKHDDM_01983	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKEKHDDM_01984	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MKEKHDDM_01985	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKEKHDDM_01986	1.23e-169	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_01987	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MKEKHDDM_01988	1.76e-165	yodH	-	-	Q	-	-	-	Methyltransferase
MKEKHDDM_01989	6.87e-50	yodI	-	-	-	-	-	-	-
MKEKHDDM_01990	4.49e-192	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MKEKHDDM_01991	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MKEKHDDM_01993	3.88e-71	yodL	-	-	S	-	-	-	YodL-like
MKEKHDDM_01994	1.83e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MKEKHDDM_01995	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
MKEKHDDM_01997	7.75e-161	yodN	-	-	-	-	-	-	-
MKEKHDDM_01998	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MKEKHDDM_01999	1.4e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MKEKHDDM_02000	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MKEKHDDM_02001	2.95e-205	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MKEKHDDM_02002	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MKEKHDDM_02003	1.55e-158	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKEKHDDM_02004	6.87e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKEKHDDM_02005	1.69e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKEKHDDM_02006	8e-82	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MKEKHDDM_02008	1.34e-183	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MKEKHDDM_02009	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MKEKHDDM_02010	3.32e-62	cgeC	-	-	-	ko:K06321	-	ko00000	-
MKEKHDDM_02011	1.55e-90	cgeA	-	-	-	ko:K06319	-	ko00000	-
MKEKHDDM_02012	1.29e-230	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MKEKHDDM_02013	1.11e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MKEKHDDM_02014	3.54e-95	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKEKHDDM_02020	1.32e-101	-	-	-	-	-	-	-	-
MKEKHDDM_02024	7.84e-101	yoqH	-	-	M	-	-	-	LysM domain
MKEKHDDM_02025	2.56e-250	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKEKHDDM_02027	1.19e-51	-	-	-	H	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_02028	2.89e-109	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MKEKHDDM_02029	2.42e-280	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MKEKHDDM_02030	1.73e-108	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MKEKHDDM_02031	2.08e-108	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MKEKHDDM_02032	0.0	yokA	-	-	L	-	-	-	Recombinase
MKEKHDDM_02033	1.02e-135	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKEKHDDM_02034	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MKEKHDDM_02035	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKEKHDDM_02036	8.22e-90	ypoP	-	-	K	-	-	-	transcriptional
MKEKHDDM_02037	3.78e-124	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02038	1.61e-172	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKEKHDDM_02039	5.51e-147	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MKEKHDDM_02040	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MKEKHDDM_02041	4.25e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKEKHDDM_02042	4.45e-228	yplP	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02043	7.44e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MKEKHDDM_02044	7.27e-252	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKEKHDDM_02045	1.16e-148	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKEKHDDM_02046	3.01e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKEKHDDM_02047	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKEKHDDM_02048	6.48e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MKEKHDDM_02049	1e-171	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MKEKHDDM_02050	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MKEKHDDM_02051	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MKEKHDDM_02052	9.43e-203	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKEKHDDM_02053	8.18e-78	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKEKHDDM_02054	2.76e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MKEKHDDM_02055	1.89e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKEKHDDM_02056	5.21e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MKEKHDDM_02057	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MKEKHDDM_02058	1.27e-17	degR	-	-	-	-	-	-	-
MKEKHDDM_02059	1.13e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MKEKHDDM_02060	3.82e-39	ypeQ	-	-	S	-	-	-	Zinc-finger
MKEKHDDM_02061	5.91e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MKEKHDDM_02062	9.33e-153	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKEKHDDM_02063	2.11e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MKEKHDDM_02065	1.11e-208	ypcP	-	-	L	-	-	-	5'3' exonuclease
MKEKHDDM_02066	2.44e-10	-	-	-	-	-	-	-	-
MKEKHDDM_02067	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MKEKHDDM_02068	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MKEKHDDM_02069	2.96e-116	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MKEKHDDM_02070	1.79e-268	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MKEKHDDM_02071	5.29e-138	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_02072	2.21e-66	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
MKEKHDDM_02073	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MKEKHDDM_02074	1.13e-23	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKEKHDDM_02075	3.64e-129	yrdC	-	-	Q	-	-	-	Isochorismatase family
MKEKHDDM_02076	3.16e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MKEKHDDM_02077	5.09e-202	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MKEKHDDM_02079	3.45e-114	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKEKHDDM_02089	1.1e-189	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MKEKHDDM_02098	1.83e-36	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKEKHDDM_02099	4.65e-193	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKEKHDDM_02103	1.8e-72	ymaB	-	-	S	-	-	-	MutT family
MKEKHDDM_02106	2.78e-37	-	-	-	O	-	-	-	Glutaredoxin
MKEKHDDM_02107	3.89e-212	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_02109	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_02110	1.31e-74	-	-	-	S	-	-	-	NrdI Flavodoxin like
MKEKHDDM_02118	3.06e-26	-	-	-	-	-	-	-	-
MKEKHDDM_02120	4.98e-17	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MKEKHDDM_02126	8.5e-210	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
MKEKHDDM_02129	2.83e-116	yorS	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MKEKHDDM_02130	5.04e-91	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
MKEKHDDM_02133	3.5e-30	-	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02134	0.0	-	-	-	S	-	-	-	Bacterial DNA polymerase III alpha subunit
MKEKHDDM_02135	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MKEKHDDM_02136	6.96e-263	-	-	-	L	-	-	-	DNA primase activity
MKEKHDDM_02137	0.0	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
MKEKHDDM_02138	3.83e-104	-	-	-	-	-	-	-	-
MKEKHDDM_02139	1.71e-217	-	-	-	L	-	-	-	AAA domain
MKEKHDDM_02140	9.76e-203	-	-	-	-	-	-	-	-
MKEKHDDM_02144	1.04e-277	-	-	-	M	-	-	-	Parallel beta-helix repeats
MKEKHDDM_02145	8.37e-108	-	-	-	S	-	-	-	Pfam:DUF867
MKEKHDDM_02147	2.56e-28	-	-	-	S	-	-	-	YopX protein
MKEKHDDM_02149	5.68e-202	-	-	-	-	-	-	-	-
MKEKHDDM_02151	1.57e-159	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MKEKHDDM_02152	1.12e-175	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
MKEKHDDM_02154	2.09e-35	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
MKEKHDDM_02156	4.58e-95	-	-	-	-	-	-	-	-
MKEKHDDM_02167	5.8e-31	-	-	-	-	-	-	-	-
MKEKHDDM_02170	1.62e-08	-	-	-	S	-	-	-	YopX protein
MKEKHDDM_02174	9.24e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_02176	1.47e-235	-	-	-	-	-	-	-	-
MKEKHDDM_02183	7.58e-80	-	-	-	-	-	-	-	-
MKEKHDDM_02186	2.58e-254	-	-	-	-	-	-	-	-
MKEKHDDM_02187	5.59e-08	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
MKEKHDDM_02191	1.66e-33	-	-	-	-	-	-	-	-
MKEKHDDM_02194	1.31e-134	-	-	-	S	-	-	-	KAP family P-loop domain
MKEKHDDM_02198	6.23e-13	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MKEKHDDM_02199	5.36e-92	yoaW	-	-	-	-	-	-	-
MKEKHDDM_02201	0.000613	-	-	-	I	-	-	-	Acyltransferase family
MKEKHDDM_02207	9.78e-251	-	-	-	L	-	-	-	Domain of unknown function (DUF4942)
MKEKHDDM_02208	3.18e-05	-	-	-	L	-	-	-	SNF2 family N-terminal domain
MKEKHDDM_02209	3.94e-202	-	-	-	-	-	-	-	-
MKEKHDDM_02212	6.78e-71	-	-	-	D	-	-	-	Tubulin/FtsZ family, GTPase domain
MKEKHDDM_02216	0.0	-	-	-	-	-	-	-	-
MKEKHDDM_02217	8.24e-48	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKEKHDDM_02222	3.48e-288	-	-	-	S	-	-	-	hydrolase activity
MKEKHDDM_02224	1.85e-98	-	-	-	-	-	-	-	-
MKEKHDDM_02225	3.85e-246	-	-	-	-	-	-	-	-
MKEKHDDM_02226	2.59e-84	-	-	-	-	-	-	-	-
MKEKHDDM_02227	3.2e-57	-	-	-	-	-	-	-	-
MKEKHDDM_02229	3.41e-232	-	-	-	-	-	-	-	-
MKEKHDDM_02230	1.27e-110	-	-	-	-	-	-	-	-
MKEKHDDM_02233	1.61e-151	-	-	-	-	-	-	-	-
MKEKHDDM_02234	3.62e-112	-	-	-	-	-	-	-	-
MKEKHDDM_02235	1.63e-149	-	-	-	-	-	-	-	-
MKEKHDDM_02236	2.52e-77	-	-	-	-	-	-	-	-
MKEKHDDM_02238	3.02e-65	-	-	-	-	-	-	-	-
MKEKHDDM_02239	1.11e-94	-	-	-	-	-	-	-	-
MKEKHDDM_02241	2.95e-75	-	-	-	-	-	-	-	-
MKEKHDDM_02242	1.74e-62	-	-	-	-	-	-	-	-
MKEKHDDM_02243	4.99e-82	-	-	-	S	-	-	-	DNA integration
MKEKHDDM_02244	1.83e-26	-	-	-	-	-	-	-	-
MKEKHDDM_02247	1.36e-74	-	-	-	-	-	-	-	-
MKEKHDDM_02248	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
MKEKHDDM_02249	5.95e-162	-	-	-	S	-	-	-	Phage tail protein
MKEKHDDM_02250	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
MKEKHDDM_02251	7.35e-132	-	-	-	-	-	-	-	-
MKEKHDDM_02252	1.52e-291	-	-	-	M	-	-	-	Pectate lyase superfamily protein
MKEKHDDM_02253	1.13e-99	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKEKHDDM_02255	7.46e-45	-	-	-	S	-	-	-	Bacteriophage holin
MKEKHDDM_02257	1.44e-06	-	-	-	-	-	-	-	-
MKEKHDDM_02258	1.18e-118	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_02260	1.25e-282	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKEKHDDM_02261	3.11e-54	-	-	-	S	-	-	-	YolD-like protein
MKEKHDDM_02262	5.12e-162	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MKEKHDDM_02264	1.52e-74	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MKEKHDDM_02265	3.75e-80	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MKEKHDDM_02266	1.25e-108	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
MKEKHDDM_02267	0.0	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MKEKHDDM_02268	1.27e-109	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MKEKHDDM_02269	6.97e-47	-	-	-	L	-	-	-	Recombinase
MKEKHDDM_02270	1.01e-79	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MKEKHDDM_02271	1.16e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKEKHDDM_02272	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKEKHDDM_02273	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MKEKHDDM_02275	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
MKEKHDDM_02276	4.68e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MKEKHDDM_02277	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKEKHDDM_02278	2.69e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MKEKHDDM_02279	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MKEKHDDM_02280	3.17e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MKEKHDDM_02281	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MKEKHDDM_02282	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MKEKHDDM_02283	5.09e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKEKHDDM_02284	1.72e-83	yppG	-	-	S	-	-	-	YppG-like protein
MKEKHDDM_02288	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
MKEKHDDM_02289	3.32e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MKEKHDDM_02290	1.47e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKEKHDDM_02291	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKEKHDDM_02292	7.07e-117	ypoC	-	-	-	-	-	-	-
MKEKHDDM_02293	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKEKHDDM_02294	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MKEKHDDM_02295	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MKEKHDDM_02296	4.01e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MKEKHDDM_02297	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02298	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MKEKHDDM_02299	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MKEKHDDM_02300	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKEKHDDM_02301	5.71e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKEKHDDM_02302	9.39e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MKEKHDDM_02303	9.42e-232	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKEKHDDM_02304	1.98e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKEKHDDM_02305	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MKEKHDDM_02306	1.23e-167	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MKEKHDDM_02307	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MKEKHDDM_02308	1.39e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKEKHDDM_02309	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MKEKHDDM_02310	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_02311	4.06e-289	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MKEKHDDM_02312	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
MKEKHDDM_02313	9.19e-137	ypjA	-	-	S	-	-	-	membrane
MKEKHDDM_02314	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MKEKHDDM_02315	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MKEKHDDM_02316	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MKEKHDDM_02317	9.97e-103	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MKEKHDDM_02318	1.06e-128	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MKEKHDDM_02319	7.49e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKEKHDDM_02320	4.03e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKEKHDDM_02321	2.93e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MKEKHDDM_02322	2.14e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKEKHDDM_02323	1.62e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKEKHDDM_02324	1.73e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKEKHDDM_02325	9.06e-151	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MKEKHDDM_02326	4.97e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MKEKHDDM_02327	5.82e-212	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKEKHDDM_02328	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKEKHDDM_02329	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MKEKHDDM_02330	7.79e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKEKHDDM_02331	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKEKHDDM_02332	3.54e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MKEKHDDM_02333	2.35e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MKEKHDDM_02334	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKEKHDDM_02335	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKEKHDDM_02336	3.96e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MKEKHDDM_02337	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MKEKHDDM_02338	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MKEKHDDM_02339	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKEKHDDM_02340	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKEKHDDM_02341	5.64e-172	yphF	-	-	-	-	-	-	-
MKEKHDDM_02342	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MKEKHDDM_02343	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MKEKHDDM_02344	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MKEKHDDM_02345	3.58e-135	yphA	-	-	-	-	-	-	-
MKEKHDDM_02346	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
MKEKHDDM_02347	1.02e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKEKHDDM_02348	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MKEKHDDM_02349	2.02e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MKEKHDDM_02350	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MKEKHDDM_02351	4.07e-78	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MKEKHDDM_02352	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MKEKHDDM_02353	2.54e-211	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MKEKHDDM_02354	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MKEKHDDM_02355	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MKEKHDDM_02356	7.37e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKEKHDDM_02357	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKEKHDDM_02358	4.68e-189	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MKEKHDDM_02359	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MKEKHDDM_02360	2.5e-133	ypbE	-	-	M	-	-	-	Lysin motif
MKEKHDDM_02361	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MKEKHDDM_02362	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKEKHDDM_02363	3.02e-253	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MKEKHDDM_02364	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MKEKHDDM_02365	6.2e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKEKHDDM_02366	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKEKHDDM_02367	2.02e-249	rsiX	-	-	-	-	-	-	-
MKEKHDDM_02368	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKEKHDDM_02369	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_02370	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_02371	4.39e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MKEKHDDM_02372	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MKEKHDDM_02373	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MKEKHDDM_02374	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKEKHDDM_02375	3.66e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MKEKHDDM_02376	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MKEKHDDM_02377	2.57e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKEKHDDM_02378	6.14e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MKEKHDDM_02379	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKEKHDDM_02380	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKEKHDDM_02382	2.33e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MKEKHDDM_02383	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKEKHDDM_02384	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKEKHDDM_02385	7.34e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKEKHDDM_02386	6.59e-143	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MKEKHDDM_02387	1.53e-267	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKEKHDDM_02388	4.92e-71	ypuD	-	-	-	-	-	-	-
MKEKHDDM_02389	3.8e-130	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKEKHDDM_02390	1.36e-105	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
MKEKHDDM_02391	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKEKHDDM_02392	6.31e-199	ypuA	-	-	S	-	-	-	Secreted protein
MKEKHDDM_02393	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKEKHDDM_02394	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MKEKHDDM_02395	1.31e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MKEKHDDM_02396	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MKEKHDDM_02397	8.19e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MKEKHDDM_02398	9.92e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MKEKHDDM_02399	1.43e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MKEKHDDM_02400	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MKEKHDDM_02401	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_02402	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MKEKHDDM_02403	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MKEKHDDM_02404	4.99e-273	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKEKHDDM_02405	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKEKHDDM_02406	4.97e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKEKHDDM_02407	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MKEKHDDM_02408	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MKEKHDDM_02409	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MKEKHDDM_02410	8.31e-141	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MKEKHDDM_02411	4.38e-47	yqkK	-	-	-	-	-	-	-
MKEKHDDM_02412	6.84e-31	-	-	-	-	-	-	-	-
MKEKHDDM_02413	8.31e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MKEKHDDM_02414	2.15e-314	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKEKHDDM_02415	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MKEKHDDM_02416	5.31e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MKEKHDDM_02417	1.15e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02418	5.91e-280	yqxK	-	-	L	-	-	-	DNA helicase
MKEKHDDM_02419	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MKEKHDDM_02420	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MKEKHDDM_02421	1.47e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MKEKHDDM_02422	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MKEKHDDM_02423	6.77e-225	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKEKHDDM_02424	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MKEKHDDM_02425	5.4e-80	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MKEKHDDM_02426	1.44e-223	yqkA	-	-	K	-	-	-	GrpB protein
MKEKHDDM_02427	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MKEKHDDM_02428	2.81e-115	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MKEKHDDM_02429	5.69e-300	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKEKHDDM_02430	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
MKEKHDDM_02432	6.44e-243	yueF	-	-	S	-	-	-	transporter activity
MKEKHDDM_02434	2.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_02435	4.46e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MKEKHDDM_02436	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MKEKHDDM_02437	3.39e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_02438	6.83e-224	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKEKHDDM_02439	2.76e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKEKHDDM_02440	1.68e-175	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MKEKHDDM_02441	7.87e-306	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MKEKHDDM_02442	4e-281	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKEKHDDM_02443	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MKEKHDDM_02444	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02445	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02446	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02447	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02448	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02449	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKEKHDDM_02450	2.78e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MKEKHDDM_02451	5.63e-316	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKEKHDDM_02454	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKEKHDDM_02455	5.26e-123	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MKEKHDDM_02456	1.73e-42	-	-	-	S	-	-	-	GlpM protein
MKEKHDDM_02457	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKEKHDDM_02458	1.11e-189	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKEKHDDM_02459	4.79e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKEKHDDM_02460	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKEKHDDM_02461	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKEKHDDM_02462	1.16e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKEKHDDM_02463	1.3e-34	yqzJ	-	-	-	-	-	-	-
MKEKHDDM_02464	2.05e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKEKHDDM_02465	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MKEKHDDM_02466	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKEKHDDM_02467	2.3e-96	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MKEKHDDM_02469	9.08e-124	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02470	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MKEKHDDM_02471	2.58e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKEKHDDM_02472	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKEKHDDM_02473	2.38e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKEKHDDM_02474	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MKEKHDDM_02475	2.46e-218	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKEKHDDM_02476	7.25e-284	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKEKHDDM_02477	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKEKHDDM_02478	2.75e-222	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKEKHDDM_02479	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKEKHDDM_02480	6.96e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MKEKHDDM_02481	1.58e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKEKHDDM_02482	1.67e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MKEKHDDM_02483	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MKEKHDDM_02484	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MKEKHDDM_02485	4e-205	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKEKHDDM_02486	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MKEKHDDM_02487	4.18e-262	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKEKHDDM_02488	1.51e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MKEKHDDM_02489	4.86e-197	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MKEKHDDM_02490	1.95e-272	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MKEKHDDM_02491	3.83e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKEKHDDM_02492	1.97e-136	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MKEKHDDM_02494	7.97e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKEKHDDM_02495	6.93e-147	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
MKEKHDDM_02497	2.77e-273	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MKEKHDDM_02500	5.23e-277	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKEKHDDM_02501	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MKEKHDDM_02502	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MKEKHDDM_02503	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MKEKHDDM_02504	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MKEKHDDM_02505	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MKEKHDDM_02506	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKEKHDDM_02507	9.49e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKEKHDDM_02508	5.39e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKEKHDDM_02509	5.6e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKEKHDDM_02510	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKEKHDDM_02511	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKEKHDDM_02512	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02513	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MKEKHDDM_02514	2.32e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKEKHDDM_02515	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MKEKHDDM_02516	1.16e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MKEKHDDM_02517	2.12e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MKEKHDDM_02518	6.09e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MKEKHDDM_02519	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MKEKHDDM_02520	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MKEKHDDM_02521	1.4e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MKEKHDDM_02522	1.04e-219	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MKEKHDDM_02523	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MKEKHDDM_02524	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKEKHDDM_02525	6.04e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKEKHDDM_02526	3.99e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MKEKHDDM_02527	2.1e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MKEKHDDM_02528	1.54e-82	yqhP	-	-	-	-	-	-	-
MKEKHDDM_02529	2.34e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKEKHDDM_02530	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MKEKHDDM_02531	1.12e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MKEKHDDM_02532	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MKEKHDDM_02533	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKEKHDDM_02534	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKEKHDDM_02535	9.52e-264	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MKEKHDDM_02536	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKEKHDDM_02537	3.06e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MKEKHDDM_02538	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MKEKHDDM_02539	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MKEKHDDM_02540	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MKEKHDDM_02541	1.89e-102	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MKEKHDDM_02542	8.05e-157	yqxM	-	-	-	ko:K19433	-	ko00000	-
MKEKHDDM_02543	5.66e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MKEKHDDM_02544	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
MKEKHDDM_02545	4.9e-83	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MKEKHDDM_02546	6.35e-85	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MKEKHDDM_02547	6.31e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MKEKHDDM_02548	3.93e-94	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
MKEKHDDM_02549	1.82e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MKEKHDDM_02550	1.89e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MKEKHDDM_02551	3.84e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKEKHDDM_02552	6.43e-239	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MKEKHDDM_02553	6.5e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKEKHDDM_02554	2.05e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKEKHDDM_02556	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MKEKHDDM_02557	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MKEKHDDM_02558	3.45e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MKEKHDDM_02559	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MKEKHDDM_02560	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
MKEKHDDM_02561	6.3e-255	yqgU	-	-	-	-	-	-	-
MKEKHDDM_02562	1.24e-284	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MKEKHDDM_02563	7.14e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MKEKHDDM_02564	1.4e-273	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKEKHDDM_02565	5.38e-11	yqgO	-	-	-	-	-	-	-
MKEKHDDM_02566	8.62e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKEKHDDM_02567	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MKEKHDDM_02568	3.42e-68	yqzD	-	-	-	-	-	-	-
MKEKHDDM_02569	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKEKHDDM_02570	2.32e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKEKHDDM_02571	7.14e-187	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKEKHDDM_02572	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MKEKHDDM_02573	2.48e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MKEKHDDM_02574	2.24e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MKEKHDDM_02575	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MKEKHDDM_02576	2.37e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MKEKHDDM_02577	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MKEKHDDM_02578	4.77e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MKEKHDDM_02579	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MKEKHDDM_02580	1.84e-64	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MKEKHDDM_02581	2.3e-255	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKEKHDDM_02582	3.34e-80	yqfX	-	-	S	-	-	-	membrane
MKEKHDDM_02583	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MKEKHDDM_02584	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MKEKHDDM_02585	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_02586	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MKEKHDDM_02587	2.86e-212	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKEKHDDM_02588	6.06e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKEKHDDM_02589	3.93e-87	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MKEKHDDM_02590	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKEKHDDM_02591	2.18e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKEKHDDM_02592	1.16e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MKEKHDDM_02593	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MKEKHDDM_02594	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKEKHDDM_02595	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKEKHDDM_02596	1.36e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MKEKHDDM_02597	2.22e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKEKHDDM_02598	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
MKEKHDDM_02599	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MKEKHDDM_02600	1.49e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MKEKHDDM_02601	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MKEKHDDM_02602	6e-24	-	-	-	S	-	-	-	YqzL-like protein
MKEKHDDM_02603	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKEKHDDM_02604	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKEKHDDM_02605	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MKEKHDDM_02606	1.44e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKEKHDDM_02607	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MKEKHDDM_02608	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MKEKHDDM_02609	3.72e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MKEKHDDM_02610	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MKEKHDDM_02611	8.89e-86	yqfB	-	-	-	-	-	-	-
MKEKHDDM_02612	4.48e-189	yqfA	-	-	S	-	-	-	UPF0365 protein
MKEKHDDM_02613	1.34e-295	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MKEKHDDM_02614	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MKEKHDDM_02615	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MKEKHDDM_02616	1.37e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MKEKHDDM_02617	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MKEKHDDM_02618	2.91e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKEKHDDM_02619	6.58e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MKEKHDDM_02620	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKEKHDDM_02621	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MKEKHDDM_02622	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKEKHDDM_02623	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKEKHDDM_02624	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MKEKHDDM_02625	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKEKHDDM_02626	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MKEKHDDM_02627	9.09e-280	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MKEKHDDM_02628	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKEKHDDM_02629	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MKEKHDDM_02630	3.68e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MKEKHDDM_02631	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MKEKHDDM_02632	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MKEKHDDM_02633	2.06e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MKEKHDDM_02634	8.04e-191	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKEKHDDM_02635	8.39e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
MKEKHDDM_02636	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKEKHDDM_02637	2.38e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MKEKHDDM_02638	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKEKHDDM_02639	3.12e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MKEKHDDM_02640	2.32e-198	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKEKHDDM_02641	7.93e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MKEKHDDM_02642	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MKEKHDDM_02644	3.07e-179	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKEKHDDM_02645	8.09e-181	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKEKHDDM_02646	2.92e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MKEKHDDM_02647	4.51e-47	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MKEKHDDM_02648	1.82e-276	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MKEKHDDM_02649	5.58e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKEKHDDM_02650	2.74e-33	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MKEKHDDM_02651	4.64e-140	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MKEKHDDM_02652	3.94e-27	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MKEKHDDM_02654	2.03e-173	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Reductase
MKEKHDDM_02655	2.72e-91	-	-	-	K	-	-	-	MerR family transcriptional regulator
MKEKHDDM_02656	2.4e-20	xkdG	-	-	S	-	-	-	Phage capsid family
MKEKHDDM_02657	3.89e-206	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MKEKHDDM_02658	5.25e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKEKHDDM_02659	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Belongs to the PsiE family
MKEKHDDM_02660	2.67e-308	yrkQ	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_02661	7.69e-159	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MKEKHDDM_02662	2.2e-273	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKEKHDDM_02663	1.28e-129	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKEKHDDM_02664	2.23e-129	yqaC	-	-	F	-	-	-	adenylate kinase activity
MKEKHDDM_02665	5.25e-41	-	-	-	K	-	-	-	acetyltransferase
MKEKHDDM_02666	7.59e-280	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_02667	2.48e-104	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MKEKHDDM_02668	6.77e-121	-	-	-	S	-	-	-	DinB family
MKEKHDDM_02669	3.98e-188	supH	-	-	S	-	-	-	hydrolase
MKEKHDDM_02670	1.23e-173	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MKEKHDDM_02671	4.12e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MKEKHDDM_02672	1.78e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKEKHDDM_02673	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_02674	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MKEKHDDM_02675	4.86e-233	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MKEKHDDM_02676	7.97e-108	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKEKHDDM_02677	1.53e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02678	3.77e-270	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_02679	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MKEKHDDM_02680	3.36e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MKEKHDDM_02681	5.22e-120	yrhH	-	-	Q	-	-	-	methyltransferase
MKEKHDDM_02682	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MKEKHDDM_02683	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MKEKHDDM_02684	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MKEKHDDM_02685	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MKEKHDDM_02686	4.76e-106	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKEKHDDM_02687	3.31e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
MKEKHDDM_02688	4.39e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKEKHDDM_02689	2.28e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MKEKHDDM_02690	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKEKHDDM_02691	8.44e-154	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MKEKHDDM_02692	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MKEKHDDM_02693	3.56e-124	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MKEKHDDM_02694	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MKEKHDDM_02695	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKEKHDDM_02696	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MKEKHDDM_02697	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MKEKHDDM_02698	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MKEKHDDM_02699	2.22e-151	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MKEKHDDM_02700	1.63e-258	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKEKHDDM_02701	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MKEKHDDM_02702	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKEKHDDM_02703	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MKEKHDDM_02704	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKEKHDDM_02705	4.67e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
MKEKHDDM_02706	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKEKHDDM_02707	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKEKHDDM_02708	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKEKHDDM_02709	1.87e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKEKHDDM_02710	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MKEKHDDM_02711	8.4e-42	yrzR	-	-	-	-	-	-	-
MKEKHDDM_02712	2.92e-106	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_02713	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKEKHDDM_02714	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKEKHDDM_02715	5.88e-281	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKEKHDDM_02716	2.1e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKEKHDDM_02717	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_02718	3.74e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MKEKHDDM_02719	2.39e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MKEKHDDM_02720	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKEKHDDM_02721	6.05e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MKEKHDDM_02724	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MKEKHDDM_02725	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKEKHDDM_02726	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKEKHDDM_02727	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKEKHDDM_02728	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MKEKHDDM_02729	7.78e-63	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MKEKHDDM_02730	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MKEKHDDM_02731	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKEKHDDM_02732	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MKEKHDDM_02733	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_02734	2.89e-143	yrbG	-	-	S	-	-	-	membrane
MKEKHDDM_02735	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MKEKHDDM_02736	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MKEKHDDM_02737	6.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKEKHDDM_02738	5.79e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKEKHDDM_02739	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MKEKHDDM_02740	6.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKEKHDDM_02741	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKEKHDDM_02742	4.21e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MKEKHDDM_02744	8.92e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKEKHDDM_02745	8.47e-257	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MKEKHDDM_02746	1.04e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKEKHDDM_02747	3.69e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MKEKHDDM_02748	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKEKHDDM_02749	5.48e-283	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKEKHDDM_02750	3.02e-124	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MKEKHDDM_02751	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MKEKHDDM_02752	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MKEKHDDM_02753	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKEKHDDM_02754	1.48e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MKEKHDDM_02755	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MKEKHDDM_02756	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MKEKHDDM_02757	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MKEKHDDM_02758	1.71e-204	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MKEKHDDM_02759	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKEKHDDM_02760	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MKEKHDDM_02761	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKEKHDDM_02762	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MKEKHDDM_02763	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MKEKHDDM_02764	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MKEKHDDM_02765	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MKEKHDDM_02766	2.36e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MKEKHDDM_02767	1.27e-208	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MKEKHDDM_02768	1.49e-170	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MKEKHDDM_02769	2.66e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MKEKHDDM_02770	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKEKHDDM_02771	1.53e-35	-	-	-	-	-	-	-	-
MKEKHDDM_02772	1.55e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKEKHDDM_02773	6.1e-295	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MKEKHDDM_02774	1.62e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKEKHDDM_02775	1.4e-235	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MKEKHDDM_02776	1.62e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKEKHDDM_02777	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MKEKHDDM_02778	1.88e-186	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MKEKHDDM_02779	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKEKHDDM_02780	3.78e-112	ysxD	-	-	-	-	-	-	-
MKEKHDDM_02781	1.79e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MKEKHDDM_02782	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKEKHDDM_02783	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MKEKHDDM_02784	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKEKHDDM_02785	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKEKHDDM_02786	9.54e-241	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MKEKHDDM_02787	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKEKHDDM_02788	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKEKHDDM_02789	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKEKHDDM_02790	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKEKHDDM_02791	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKEKHDDM_02792	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKEKHDDM_02793	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKEKHDDM_02796	1.12e-241	-	-	-	-	-	-	-	-
MKEKHDDM_02798	2.93e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MKEKHDDM_02799	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MKEKHDDM_02800	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MKEKHDDM_02804	1.16e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MKEKHDDM_02805	3.2e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKEKHDDM_02806	1.44e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKEKHDDM_02807	2.58e-254	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MKEKHDDM_02808	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MKEKHDDM_02809	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKEKHDDM_02810	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_02811	2.67e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MKEKHDDM_02812	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKEKHDDM_02813	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKEKHDDM_02814	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MKEKHDDM_02815	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MKEKHDDM_02816	8.64e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKEKHDDM_02817	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKEKHDDM_02818	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MKEKHDDM_02819	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MKEKHDDM_02820	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MKEKHDDM_02821	1.74e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MKEKHDDM_02822	2.48e-178	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MKEKHDDM_02823	1.26e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_02824	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKEKHDDM_02825	1.57e-159	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MKEKHDDM_02826	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MKEKHDDM_02827	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKEKHDDM_02828	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MKEKHDDM_02829	3.5e-108	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MKEKHDDM_02830	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKEKHDDM_02831	1.03e-213	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKEKHDDM_02832	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKEKHDDM_02833	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKEKHDDM_02834	3.65e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKEKHDDM_02835	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MKEKHDDM_02836	1.02e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MKEKHDDM_02837	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
MKEKHDDM_02838	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MKEKHDDM_02839	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MKEKHDDM_02840	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MKEKHDDM_02841	6.84e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MKEKHDDM_02842	6.22e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKEKHDDM_02843	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MKEKHDDM_02844	1.65e-285	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MKEKHDDM_02845	2.29e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MKEKHDDM_02846	3.21e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MKEKHDDM_02847	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MKEKHDDM_02848	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MKEKHDDM_02849	4.91e-241	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MKEKHDDM_02850	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MKEKHDDM_02851	9.71e-90	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MKEKHDDM_02852	7.74e-56	ysdA	-	-	S	-	-	-	Membrane
MKEKHDDM_02853	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKEKHDDM_02854	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MKEKHDDM_02855	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKEKHDDM_02856	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKEKHDDM_02857	1.12e-68	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
MKEKHDDM_02858	3e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MKEKHDDM_02859	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_02860	7.21e-194	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MKEKHDDM_02861	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKEKHDDM_02862	1.91e-195	ytxC	-	-	S	-	-	-	YtxC-like family
MKEKHDDM_02863	5.42e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MKEKHDDM_02864	1.42e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MKEKHDDM_02865	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MKEKHDDM_02866	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKEKHDDM_02867	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKEKHDDM_02868	2.19e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKEKHDDM_02869	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02870	1.97e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MKEKHDDM_02871	5.53e-206	ytbE	-	-	S	-	-	-	reductase
MKEKHDDM_02872	9.83e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKEKHDDM_02873	2e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKEKHDDM_02874	1.03e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKEKHDDM_02875	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKEKHDDM_02876	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MKEKHDDM_02877	1.38e-165	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_02878	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MKEKHDDM_02879	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MKEKHDDM_02880	2.02e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKEKHDDM_02881	1.58e-82	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MKEKHDDM_02882	2.3e-95	ytwI	-	-	S	-	-	-	membrane
MKEKHDDM_02883	4.05e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MKEKHDDM_02884	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MKEKHDDM_02885	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MKEKHDDM_02886	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKEKHDDM_02887	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MKEKHDDM_02888	3.59e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKEKHDDM_02889	4.93e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKEKHDDM_02890	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MKEKHDDM_02891	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MKEKHDDM_02892	2.64e-114	ytrI	-	-	-	-	-	-	-
MKEKHDDM_02893	1e-31	-	-	-	-	-	-	-	-
MKEKHDDM_02894	3.04e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MKEKHDDM_02895	3.05e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MKEKHDDM_02896	6.77e-305	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MKEKHDDM_02897	4.86e-165	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MKEKHDDM_02898	8.38e-184	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_02900	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MKEKHDDM_02901	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKEKHDDM_02902	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MKEKHDDM_02903	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKEKHDDM_02904	3.18e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MKEKHDDM_02905	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKEKHDDM_02906	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MKEKHDDM_02907	3.66e-156	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MKEKHDDM_02908	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
MKEKHDDM_02909	1.06e-233	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MKEKHDDM_02910	1.91e-195	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKEKHDDM_02911	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MKEKHDDM_02912	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKEKHDDM_02913	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MKEKHDDM_02914	2.09e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKEKHDDM_02915	3.9e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKEKHDDM_02916	1.96e-308	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MKEKHDDM_02917	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKEKHDDM_02918	1.46e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MKEKHDDM_02919	2.41e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02920	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MKEKHDDM_02921	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MKEKHDDM_02922	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKEKHDDM_02923	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKEKHDDM_02924	7.39e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MKEKHDDM_02925	7.52e-283	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKEKHDDM_02927	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MKEKHDDM_02929	2.14e-179	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MKEKHDDM_02930	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKEKHDDM_02931	2.22e-190	-	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_02932	5.77e-160	ygaZ	-	-	E	-	-	-	AzlC protein
MKEKHDDM_02933	2.07e-62	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MKEKHDDM_02934	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKEKHDDM_02935	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKEKHDDM_02936	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MKEKHDDM_02937	4.16e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MKEKHDDM_02938	1.42e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MKEKHDDM_02939	3.01e-155	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MKEKHDDM_02940	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MKEKHDDM_02941	5.91e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MKEKHDDM_02942	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MKEKHDDM_02943	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MKEKHDDM_02944	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MKEKHDDM_02945	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKEKHDDM_02946	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MKEKHDDM_02947	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKEKHDDM_02948	2.84e-137	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKEKHDDM_02949	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MKEKHDDM_02950	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
MKEKHDDM_02951	1.42e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MKEKHDDM_02952	4.33e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MKEKHDDM_02953	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
MKEKHDDM_02954	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKEKHDDM_02955	5.56e-211	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKEKHDDM_02956	6.43e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKEKHDDM_02957	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
MKEKHDDM_02958	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
MKEKHDDM_02959	8.33e-227	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MKEKHDDM_02960	2.85e-214	ytlQ	-	-	-	-	-	-	-
MKEKHDDM_02961	1.1e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKEKHDDM_02962	4.79e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKEKHDDM_02963	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MKEKHDDM_02964	2.99e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKEKHDDM_02965	3.53e-276	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MKEKHDDM_02966	6.35e-164	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKEKHDDM_02967	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MKEKHDDM_02968	8.68e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKEKHDDM_02969	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_02970	3.73e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MKEKHDDM_02971	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MKEKHDDM_02972	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MKEKHDDM_02973	7.81e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_02974	6.55e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKEKHDDM_02975	6.24e-215	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKEKHDDM_02976	1.17e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKEKHDDM_02977	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKEKHDDM_02978	1.69e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_02979	6.05e-69	ytwF	-	-	P	-	-	-	Sulfurtransferase
MKEKHDDM_02980	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MKEKHDDM_02981	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MKEKHDDM_02982	6.17e-177	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MKEKHDDM_02983	2.46e-271	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MKEKHDDM_02984	1.08e-159	ywaF	-	-	S	-	-	-	Integral membrane protein
MKEKHDDM_02985	7.27e-252	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKEKHDDM_02986	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MKEKHDDM_02987	6.58e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_02988	2.14e-222	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MKEKHDDM_02989	2.6e-166	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_02990	2.75e-287	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MKEKHDDM_02991	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_02992	5.2e-209	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MKEKHDDM_02993	2.8e-230	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKEKHDDM_02994	1.66e-222	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKEKHDDM_02995	1.46e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_02996	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MKEKHDDM_02997	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MKEKHDDM_02998	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MKEKHDDM_02999	3.1e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MKEKHDDM_03001	6.33e-186	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
MKEKHDDM_03002	1.86e-269	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MKEKHDDM_03003	5.71e-193	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKEKHDDM_03004	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKEKHDDM_03005	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_03006	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKEKHDDM_03007	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKEKHDDM_03008	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKEKHDDM_03009	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MKEKHDDM_03010	7.79e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MKEKHDDM_03011	9.14e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKEKHDDM_03012	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKEKHDDM_03013	2.16e-173	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKEKHDDM_03014	4.13e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MKEKHDDM_03015	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MKEKHDDM_03016	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MKEKHDDM_03018	1.04e-99	ytkA	-	-	S	-	-	-	YtkA-like
MKEKHDDM_03019	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKEKHDDM_03020	6.93e-53	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MKEKHDDM_03021	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKEKHDDM_03022	8.35e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MKEKHDDM_03023	1.82e-312	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MKEKHDDM_03024	2.88e-231	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MKEKHDDM_03025	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MKEKHDDM_03026	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MKEKHDDM_03027	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MKEKHDDM_03028	2.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKEKHDDM_03029	7.22e-199	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MKEKHDDM_03030	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MKEKHDDM_03031	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MKEKHDDM_03032	7.43e-170	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MKEKHDDM_03033	1.05e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MKEKHDDM_03055	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKEKHDDM_03056	5.96e-126	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MKEKHDDM_03057	2.65e-278	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MKEKHDDM_03058	1.96e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MKEKHDDM_03059	8.91e-106	yuaE	-	-	S	-	-	-	DinB superfamily
MKEKHDDM_03060	6.79e-141	-	-	-	S	-	-	-	MOSC domain
MKEKHDDM_03061	1.74e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MKEKHDDM_03062	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKEKHDDM_03063	1.18e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MKEKHDDM_03064	2.03e-122	yuaB	-	-	-	-	-	-	-
MKEKHDDM_03065	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKEKHDDM_03066	1.23e-189	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKEKHDDM_03067	1.9e-278	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKEKHDDM_03068	3.19e-158	-	-	-	G	-	-	-	Cupin
MKEKHDDM_03069	1.11e-70	yjcN	-	-	-	-	-	-	-
MKEKHDDM_03071	3.79e-186	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKEKHDDM_03072	9.96e-251	yubA	-	-	S	-	-	-	transporter activity
MKEKHDDM_03073	1.35e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKEKHDDM_03074	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MKEKHDDM_03075	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKEKHDDM_03076	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKEKHDDM_03077	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKEKHDDM_03078	1.89e-315	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKEKHDDM_03079	9.03e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MKEKHDDM_03080	3.26e-55	-	-	-	-	-	-	-	-
MKEKHDDM_03081	8.52e-244	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MKEKHDDM_03082	2.69e-98	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MKEKHDDM_03083	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKEKHDDM_03084	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKEKHDDM_03085	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MKEKHDDM_03086	1.24e-22	-	-	-	-	-	-	-	-
MKEKHDDM_03087	2.44e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MKEKHDDM_03088	5.65e-230	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MKEKHDDM_03089	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
MKEKHDDM_03091	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MKEKHDDM_03092	1.95e-133	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MKEKHDDM_03093	4.34e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
MKEKHDDM_03094	7.9e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MKEKHDDM_03095	1.65e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MKEKHDDM_03096	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MKEKHDDM_03097	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKEKHDDM_03098	1.38e-265	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MKEKHDDM_03099	7.56e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03100	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
MKEKHDDM_03101	3.5e-54	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MKEKHDDM_03102	1.92e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MKEKHDDM_03103	4.27e-291	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03104	2.4e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MKEKHDDM_03105	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MKEKHDDM_03106	2.25e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MKEKHDDM_03107	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MKEKHDDM_03108	2.16e-94	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03109	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MKEKHDDM_03110	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKEKHDDM_03111	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKEKHDDM_03112	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MKEKHDDM_03113	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_03114	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKEKHDDM_03115	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKEKHDDM_03117	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKEKHDDM_03118	5.39e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKEKHDDM_03119	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKEKHDDM_03120	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKEKHDDM_03121	5.83e-100	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKEKHDDM_03122	1.1e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKEKHDDM_03123	4.2e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MKEKHDDM_03124	4e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MKEKHDDM_03125	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_03126	7.87e-308	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03128	3.59e-82	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MKEKHDDM_03129	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
MKEKHDDM_03130	1.04e-67	yuzC	-	-	-	-	-	-	-
MKEKHDDM_03131	6.86e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MKEKHDDM_03132	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKEKHDDM_03133	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MKEKHDDM_03134	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MKEKHDDM_03135	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
MKEKHDDM_03136	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MKEKHDDM_03137	1.88e-238	yueF	-	-	S	-	-	-	transporter activity
MKEKHDDM_03138	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MKEKHDDM_03139	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKEKHDDM_03140	4.81e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_03141	8.01e-102	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MKEKHDDM_03142	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MKEKHDDM_03143	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKEKHDDM_03144	7.95e-276	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MKEKHDDM_03145	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MKEKHDDM_03146	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MKEKHDDM_03147	4.26e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
MKEKHDDM_03148	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MKEKHDDM_03149	3.58e-170	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MKEKHDDM_03150	1.91e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MKEKHDDM_03151	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_03152	4.79e-221	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MKEKHDDM_03153	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MKEKHDDM_03154	3.9e-286	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MKEKHDDM_03155	1.43e-170	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_03156	5.13e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MKEKHDDM_03157	2.18e-153	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MKEKHDDM_03158	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MKEKHDDM_03159	1.16e-275	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MKEKHDDM_03160	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKEKHDDM_03161	2.03e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MKEKHDDM_03162	7.98e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03163	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
MKEKHDDM_03164	1.39e-299	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKEKHDDM_03165	1.03e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MKEKHDDM_03167	1.15e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKEKHDDM_03168	5.68e-40	-	-	-	-	-	-	-	-
MKEKHDDM_03169	6.16e-93	-	-	-	CP	-	-	-	Membrane
MKEKHDDM_03170	1.18e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKEKHDDM_03172	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
MKEKHDDM_03174	1.48e-114	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MKEKHDDM_03175	9.01e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_03177	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MKEKHDDM_03178	5.54e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKEKHDDM_03179	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKEKHDDM_03180	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MKEKHDDM_03181	8.47e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKEKHDDM_03182	2.81e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03183	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKEKHDDM_03184	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MKEKHDDM_03185	2.26e-215	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKEKHDDM_03186	2.3e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKEKHDDM_03187	4.1e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MKEKHDDM_03188	3.12e-250	yutH	-	-	S	-	-	-	Spore coat protein
MKEKHDDM_03189	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MKEKHDDM_03190	8.34e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKEKHDDM_03191	2.67e-96	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MKEKHDDM_03192	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03193	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKEKHDDM_03194	8.24e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MKEKHDDM_03195	4.76e-168	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MKEKHDDM_03196	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKEKHDDM_03197	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKEKHDDM_03198	8.57e-216	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MKEKHDDM_03199	6.14e-80	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MKEKHDDM_03200	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MKEKHDDM_03201	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MKEKHDDM_03203	5.21e-275	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_03204	9.87e-301	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MKEKHDDM_03205	5.08e-301	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKEKHDDM_03206	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
MKEKHDDM_03207	5.52e-264	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_03208	3.41e-172	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MKEKHDDM_03209	6.2e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MKEKHDDM_03210	3.6e-209	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKEKHDDM_03211	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKEKHDDM_03212	7.41e-313	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MKEKHDDM_03213	3.87e-237	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MKEKHDDM_03214	4.05e-213	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKEKHDDM_03216	5.4e-95	-	-	-	-	-	-	-	-
MKEKHDDM_03217	9.84e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MKEKHDDM_03219	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MKEKHDDM_03220	4.51e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MKEKHDDM_03221	3.73e-157	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKEKHDDM_03222	1.51e-104	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MKEKHDDM_03223	3.58e-201	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MKEKHDDM_03224	2.14e-155	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
MKEKHDDM_03225	6.09e-70	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
MKEKHDDM_03226	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MKEKHDDM_03227	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MKEKHDDM_03228	4.66e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKEKHDDM_03229	2.48e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MKEKHDDM_03230	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MKEKHDDM_03231	8.85e-85	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKEKHDDM_03232	4.46e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MKEKHDDM_03233	2.08e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKEKHDDM_03234	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKEKHDDM_03235	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MKEKHDDM_03236	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
MKEKHDDM_03237	8.85e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MKEKHDDM_03238	4.25e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MKEKHDDM_03239	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MKEKHDDM_03240	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MKEKHDDM_03241	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKEKHDDM_03242	9.03e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MKEKHDDM_03243	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MKEKHDDM_03244	3.09e-214	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKEKHDDM_03245	2.44e-262	yusP	-	-	P	-	-	-	Major facilitator superfamily
MKEKHDDM_03246	3.2e-58	-	-	-	-	-	-	-	-
MKEKHDDM_03247	5.21e-71	yusN	-	-	M	-	-	-	Coat F domain
MKEKHDDM_03248	9.65e-92	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MKEKHDDM_03249	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MKEKHDDM_03250	1.52e-206	-	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03251	1.02e-176	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MKEKHDDM_03252	8.11e-239	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKEKHDDM_03253	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MKEKHDDM_03254	5.24e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKEKHDDM_03255	9.29e-61	-	-	-	S	-	-	-	YusW-like protein
MKEKHDDM_03256	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MKEKHDDM_03257	1.15e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_03258	8.32e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MKEKHDDM_03259	9.68e-308	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKEKHDDM_03260	3.17e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03261	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03262	4.63e-33	-	-	-	-	-	-	-	-
MKEKHDDM_03263	3.42e-201	yuxN	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03264	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKEKHDDM_03265	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MKEKHDDM_03266	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MKEKHDDM_03267	1.98e-240	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKEKHDDM_03268	1.02e-258	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKEKHDDM_03269	3.4e-138	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_03270	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03271	6.28e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MKEKHDDM_03272	5.58e-190	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MKEKHDDM_03273	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MKEKHDDM_03274	2.3e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MKEKHDDM_03275	3.37e-290	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_03276	5.36e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MKEKHDDM_03277	5.14e-287	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MKEKHDDM_03278	1.43e-228	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_03279	1.36e-214	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKEKHDDM_03280	1.23e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_03281	1.09e-218	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MKEKHDDM_03282	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_03283	7.74e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03284	1.67e-50	-	-	-	-	-	-	-	-
MKEKHDDM_03285	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MKEKHDDM_03286	3.78e-21	-	-	-	S	-	-	-	YvrJ protein family
MKEKHDDM_03287	1.08e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MKEKHDDM_03288	2.3e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MKEKHDDM_03289	1.97e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKEKHDDM_03290	2.76e-225	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_03291	1.56e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_03292	7.41e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKEKHDDM_03293	3.57e-159	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKEKHDDM_03294	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MKEKHDDM_03295	1.29e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MKEKHDDM_03296	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MKEKHDDM_03297	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MKEKHDDM_03298	4.72e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MKEKHDDM_03299	4.78e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MKEKHDDM_03300	1.57e-122	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MKEKHDDM_03301	2.05e-146	yfiK	-	-	K	-	-	-	Regulator
MKEKHDDM_03302	7.08e-252	-	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_03303	6.76e-218	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKEKHDDM_03304	2.46e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKEKHDDM_03305	3.99e-259	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKEKHDDM_03306	1.77e-200	yvgN	-	-	S	-	-	-	reductase
MKEKHDDM_03307	1.38e-113	yvgO	-	-	-	-	-	-	-
MKEKHDDM_03308	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MKEKHDDM_03309	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MKEKHDDM_03310	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKEKHDDM_03311	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKEKHDDM_03312	6.36e-130	yvgT	-	-	S	-	-	-	membrane
MKEKHDDM_03313	3.84e-190	-	-	-	S	-	-	-	Metallo-peptidase family M12
MKEKHDDM_03314	3.56e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MKEKHDDM_03315	3.33e-140	bdbD	-	-	O	-	-	-	Thioredoxin
MKEKHDDM_03316	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKEKHDDM_03317	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MKEKHDDM_03318	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MKEKHDDM_03319	9.42e-63	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MKEKHDDM_03320	8.25e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKEKHDDM_03321	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKEKHDDM_03322	4.39e-209	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKEKHDDM_03323	6.18e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKEKHDDM_03324	9.11e-92	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MKEKHDDM_03325	1.19e-186	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MKEKHDDM_03326	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_03327	1.01e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MKEKHDDM_03328	2.05e-231	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_03329	1.74e-178	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKEKHDDM_03330	5.8e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKEKHDDM_03331	1.79e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKEKHDDM_03332	3.69e-190	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKEKHDDM_03333	3.41e-167	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKEKHDDM_03334	3.1e-43	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MKEKHDDM_03335	1.87e-38	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MKEKHDDM_03336	3.82e-204	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MKEKHDDM_03337	3.94e-180	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKEKHDDM_03338	1.39e-64	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MKEKHDDM_03339	3.13e-51	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MKEKHDDM_03341	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKEKHDDM_03342	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKEKHDDM_03343	8.09e-182	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MKEKHDDM_03344	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MKEKHDDM_03345	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
MKEKHDDM_03346	9.53e-93	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MKEKHDDM_03347	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MKEKHDDM_03348	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
MKEKHDDM_03349	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MKEKHDDM_03350	4.69e-159	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MKEKHDDM_03351	1.09e-175	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKEKHDDM_03352	1.2e-157	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKEKHDDM_03353	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_03354	1.72e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKEKHDDM_03355	4.61e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKEKHDDM_03356	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKEKHDDM_03357	5.78e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKEKHDDM_03358	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKEKHDDM_03359	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKEKHDDM_03360	3.25e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKEKHDDM_03361	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKEKHDDM_03362	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKEKHDDM_03363	4.11e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKEKHDDM_03364	2.2e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MKEKHDDM_03365	1.32e-157	yvbI	-	-	M	-	-	-	Membrane
MKEKHDDM_03366	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MKEKHDDM_03367	1.11e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MKEKHDDM_03368	6.58e-271	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MKEKHDDM_03369	2.4e-229	-	-	-	-	-	-	-	-
MKEKHDDM_03370	7.75e-163	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MKEKHDDM_03371	2.89e-185	-	-	-	C	-	-	-	WbqC-like protein family
MKEKHDDM_03372	3.92e-192	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
MKEKHDDM_03373	1.69e-297	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKEKHDDM_03374	3.49e-219	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
MKEKHDDM_03375	4.83e-278	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MKEKHDDM_03376	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKEKHDDM_03377	2.94e-304	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MKEKHDDM_03378	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKEKHDDM_03379	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MKEKHDDM_03380	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKEKHDDM_03381	3.98e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MKEKHDDM_03382	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKEKHDDM_03383	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKEKHDDM_03385	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKEKHDDM_03386	9.49e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MKEKHDDM_03388	1.71e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_03389	5.29e-161	yvbU	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03390	5.22e-203	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MKEKHDDM_03391	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_03392	0.0	-	-	-	-	-	-	-	-
MKEKHDDM_03393	3.55e-231	yhjM	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03394	5.19e-148	-	-	-	S	ko:K07149	-	ko00000	Membrane
MKEKHDDM_03395	2.09e-213	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKEKHDDM_03396	1.56e-194	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
MKEKHDDM_03397	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MKEKHDDM_03398	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKEKHDDM_03399	2.91e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKEKHDDM_03400	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MKEKHDDM_03401	2.14e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKEKHDDM_03402	2.25e-284	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKEKHDDM_03403	3.1e-156	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MKEKHDDM_03404	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MKEKHDDM_03405	6.55e-309	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MKEKHDDM_03406	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
MKEKHDDM_03407	8.14e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MKEKHDDM_03408	3.31e-283	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MKEKHDDM_03409	5.73e-79	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MKEKHDDM_03410	1.92e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKEKHDDM_03411	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_03412	6.3e-251	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKEKHDDM_03413	1.57e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MKEKHDDM_03414	1.61e-249	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKEKHDDM_03415	1.71e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MKEKHDDM_03416	3.51e-272	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MKEKHDDM_03417	3.89e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKEKHDDM_03418	2.39e-275	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MKEKHDDM_03419	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKEKHDDM_03420	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MKEKHDDM_03421	4.08e-156	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MKEKHDDM_03422	6.96e-100	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MKEKHDDM_03423	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MKEKHDDM_03424	6.65e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MKEKHDDM_03425	1.45e-143	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MKEKHDDM_03426	2.22e-118	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKEKHDDM_03427	1.67e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MKEKHDDM_03428	2.86e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MKEKHDDM_03429	3.36e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MKEKHDDM_03430	1.54e-50	-	-	-	IU	-	-	-	Lipase (class 3)
MKEKHDDM_03431	1.43e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MKEKHDDM_03432	3.67e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MKEKHDDM_03433	5.51e-304	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MKEKHDDM_03434	1.86e-45	-	-	-	-	-	-	-	-
MKEKHDDM_03436	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKEKHDDM_03437	1.92e-283	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MKEKHDDM_03438	1.57e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MKEKHDDM_03439	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKEKHDDM_03440	2.26e-208	yraN	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03441	1.27e-273	yraM	-	-	S	-	-	-	PrpF protein
MKEKHDDM_03442	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MKEKHDDM_03444	3.78e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MKEKHDDM_03445	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MKEKHDDM_03446	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MKEKHDDM_03447	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKEKHDDM_03448	1.02e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKEKHDDM_03449	9.2e-104	-	-	-	M	-	-	-	Ribonuclease
MKEKHDDM_03450	6.92e-184	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MKEKHDDM_03451	2.76e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MKEKHDDM_03452	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MKEKHDDM_03453	8.99e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MKEKHDDM_03454	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MKEKHDDM_03455	5.15e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKEKHDDM_03456	8.99e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKEKHDDM_03457	7.1e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MKEKHDDM_03458	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKEKHDDM_03459	5.55e-245	sasA	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_03460	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03461	5.51e-73	-	-	-	-	-	-	-	-
MKEKHDDM_03462	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MKEKHDDM_03463	4.7e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MKEKHDDM_03464	3.4e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKEKHDDM_03465	9.3e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKEKHDDM_03466	4.87e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKEKHDDM_03467	1.17e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MKEKHDDM_03468	4.51e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKEKHDDM_03469	1.83e-148	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKEKHDDM_03470	6.03e-270	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKEKHDDM_03471	1.19e-176	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MKEKHDDM_03472	4.65e-95	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MKEKHDDM_03473	8.12e-158	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MKEKHDDM_03474	1.19e-191	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKEKHDDM_03475	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKEKHDDM_03476	3.19e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKEKHDDM_03477	9.04e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKEKHDDM_03478	1.75e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MKEKHDDM_03479	1.27e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MKEKHDDM_03480	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MKEKHDDM_03481	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MKEKHDDM_03482	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MKEKHDDM_03483	3.2e-218	yvlB	-	-	S	-	-	-	Putative adhesin
MKEKHDDM_03484	4.87e-66	yvlA	-	-	-	-	-	-	-
MKEKHDDM_03485	1.78e-51	yvkN	-	-	-	-	-	-	-
MKEKHDDM_03486	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKEKHDDM_03487	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKEKHDDM_03488	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03489	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MKEKHDDM_03490	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03491	1.45e-298	yvkA	-	-	P	-	-	-	-transporter
MKEKHDDM_03492	8.84e-62	-	-	-	Q	-	-	-	Thioesterase domain
MKEKHDDM_03493	2.72e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MKEKHDDM_03494	1.72e-58	-	-	-	E	-	-	-	Saccharopine dehydrogenase
MKEKHDDM_03495	7.41e-117	-	-	-	V	-	-	-	ABC transporter transmembrane region
MKEKHDDM_03496	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
MKEKHDDM_03497	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
MKEKHDDM_03499	8.77e-282	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKEKHDDM_03500	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MKEKHDDM_03501	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MKEKHDDM_03502	4.92e-304	ywoF	-	-	P	-	-	-	Right handed beta helix region
MKEKHDDM_03503	7.34e-197	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MKEKHDDM_03504	5.86e-157	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MKEKHDDM_03505	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MKEKHDDM_03506	4.82e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_03507	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKEKHDDM_03508	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKEKHDDM_03509	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKEKHDDM_03510	1.35e-89	-	-	-	-	-	-	-	-
MKEKHDDM_03511	5.61e-10	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MKEKHDDM_03512	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MKEKHDDM_03513	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKEKHDDM_03514	1.97e-139	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKEKHDDM_03515	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKEKHDDM_03516	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKEKHDDM_03517	2.8e-108	yviE	-	-	-	-	-	-	-
MKEKHDDM_03518	5.69e-207	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MKEKHDDM_03519	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MKEKHDDM_03520	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
MKEKHDDM_03521	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MKEKHDDM_03522	5.47e-98	yvyF	-	-	S	-	-	-	flagellar protein
MKEKHDDM_03523	2.89e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MKEKHDDM_03524	3.56e-57	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MKEKHDDM_03525	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKEKHDDM_03526	8.45e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03527	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_03528	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKEKHDDM_03529	3.43e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MKEKHDDM_03530	3.83e-230	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03531	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MKEKHDDM_03532	7.75e-302	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MKEKHDDM_03533	6.92e-186	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKEKHDDM_03534	2.99e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MKEKHDDM_03535	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MKEKHDDM_03536	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKEKHDDM_03537	3.34e-287	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MKEKHDDM_03538	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKEKHDDM_03539	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKEKHDDM_03540	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKEKHDDM_03541	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MKEKHDDM_03542	3.22e-65	-	-	-	-	-	-	-	-
MKEKHDDM_03543	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKEKHDDM_03544	7.33e-270	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKEKHDDM_03545	2.64e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKEKHDDM_03546	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKEKHDDM_03547	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MKEKHDDM_03548	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKEKHDDM_03549	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKEKHDDM_03550	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MKEKHDDM_03551	3.69e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKEKHDDM_03552	2.49e-277	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKEKHDDM_03553	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKEKHDDM_03554	2.84e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKEKHDDM_03555	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MKEKHDDM_03556	4.46e-254	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKEKHDDM_03557	1.49e-272	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MKEKHDDM_03558	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
MKEKHDDM_03559	3.45e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKEKHDDM_03560	2.3e-229	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03561	5.28e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKEKHDDM_03562	4.5e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MKEKHDDM_03563	6.71e-305	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKEKHDDM_03564	4.04e-29	ywtC	-	-	-	-	-	-	-
MKEKHDDM_03565	4e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MKEKHDDM_03566	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MKEKHDDM_03567	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MKEKHDDM_03568	6.26e-242	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MKEKHDDM_03569	4.4e-247	-	-	-	E	-	-	-	Spore germination protein
MKEKHDDM_03570	2.62e-262	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MKEKHDDM_03571	4.28e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MKEKHDDM_03572	6.91e-202	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKEKHDDM_03573	5.6e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKEKHDDM_03574	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKEKHDDM_03575	6.25e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKEKHDDM_03576	6.93e-208	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MKEKHDDM_03577	1.01e-116	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MKEKHDDM_03578	4.3e-124	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MKEKHDDM_03579	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MKEKHDDM_03580	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MKEKHDDM_03581	1.26e-213	alsR	-	-	K	-	-	-	LysR substrate binding domain
MKEKHDDM_03583	1.04e-306	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKEKHDDM_03584	3.43e-163	ywrJ	-	-	-	-	-	-	-
MKEKHDDM_03585	1.29e-185	cotB	-	-	-	ko:K06325	-	ko00000	-
MKEKHDDM_03586	2.76e-271	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MKEKHDDM_03587	9.51e-25	-	-	-	-	-	-	-	-
MKEKHDDM_03588	6.96e-145	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKEKHDDM_03589	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MKEKHDDM_03590	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MKEKHDDM_03591	4.2e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MKEKHDDM_03592	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MKEKHDDM_03593	1.06e-173	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MKEKHDDM_03594	1.31e-123	-	-	-	-	-	-	-	-
MKEKHDDM_03595	7.27e-60	-	-	-	-	-	-	-	-
MKEKHDDM_03596	8.74e-80	-	-	-	T	-	-	-	Rhs element vgr protein
MKEKHDDM_03597	2.05e-66	-	-	-	-	-	-	-	-
MKEKHDDM_03598	1.45e-47	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MKEKHDDM_03599	2.52e-128	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MKEKHDDM_03600	4.9e-118	-	-	-	-	-	-	-	-
MKEKHDDM_03601	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MKEKHDDM_03602	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKEKHDDM_03605	2.94e-192	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MKEKHDDM_03606	1.44e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKEKHDDM_03607	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MKEKHDDM_03608	2.69e-158	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MKEKHDDM_03609	1.01e-151	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MKEKHDDM_03610	1.74e-21	-	-	-	-	-	-	-	-
MKEKHDDM_03611	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MKEKHDDM_03612	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKEKHDDM_03613	1.84e-202	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKEKHDDM_03614	1.61e-179	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MKEKHDDM_03615	2.97e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MKEKHDDM_03616	4.49e-82	ywpG	-	-	-	-	-	-	-
MKEKHDDM_03617	9.16e-91	ywpF	-	-	S	-	-	-	YwpF-like protein
MKEKHDDM_03618	7.6e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKEKHDDM_03619	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKEKHDDM_03620	9.03e-256	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MKEKHDDM_03621	3.27e-188	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKEKHDDM_03622	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKEKHDDM_03623	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MKEKHDDM_03624	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MKEKHDDM_03625	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
MKEKHDDM_03626	2.89e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKEKHDDM_03627	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MKEKHDDM_03628	8.05e-312	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MKEKHDDM_03629	7.64e-131	yjgF	-	-	Q	-	-	-	Isochorismatase family
MKEKHDDM_03630	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MKEKHDDM_03631	1.29e-76	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MKEKHDDM_03632	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKEKHDDM_03633	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MKEKHDDM_03634	1.56e-93	ywnJ	-	-	S	-	-	-	VanZ like family
MKEKHDDM_03635	1.31e-188	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKEKHDDM_03636	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MKEKHDDM_03638	1.48e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MKEKHDDM_03639	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKEKHDDM_03640	8.03e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MKEKHDDM_03641	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MKEKHDDM_03642	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03643	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MKEKHDDM_03644	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MKEKHDDM_03645	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MKEKHDDM_03646	2.94e-17	csbD	-	-	K	-	-	-	CsbD-like
MKEKHDDM_03647	1.82e-106	ywmF	-	-	S	-	-	-	Peptidase M50
MKEKHDDM_03648	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_03649	4.4e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKEKHDDM_03650	2.13e-185	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKEKHDDM_03652	5.03e-157	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKEKHDDM_03653	1.42e-148	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKEKHDDM_03654	1.16e-241	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MKEKHDDM_03655	2.87e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKEKHDDM_03656	5.64e-173	ywmB	-	-	S	-	-	-	TATA-box binding
MKEKHDDM_03657	2.25e-45	ywzB	-	-	S	-	-	-	membrane
MKEKHDDM_03658	1.76e-118	ywmA	-	-	-	-	-	-	-
MKEKHDDM_03659	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MKEKHDDM_03660	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKEKHDDM_03661	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKEKHDDM_03662	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKEKHDDM_03663	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKEKHDDM_03664	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKEKHDDM_03665	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKEKHDDM_03666	1.05e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MKEKHDDM_03667	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MKEKHDDM_03668	3.18e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKEKHDDM_03669	1.7e-300	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKEKHDDM_03670	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MKEKHDDM_03671	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MKEKHDDM_03672	2.08e-101	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKEKHDDM_03673	3.35e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKEKHDDM_03674	7.58e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKEKHDDM_03675	4.23e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MKEKHDDM_03676	6.57e-153	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MKEKHDDM_03677	2.08e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MKEKHDDM_03679	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKEKHDDM_03680	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKEKHDDM_03681	9.07e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_03682	1.48e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MKEKHDDM_03683	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MKEKHDDM_03684	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MKEKHDDM_03685	2.26e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MKEKHDDM_03686	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MKEKHDDM_03687	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKEKHDDM_03688	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MKEKHDDM_03689	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKEKHDDM_03690	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKEKHDDM_03691	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MKEKHDDM_03692	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MKEKHDDM_03693	8.11e-121	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MKEKHDDM_03694	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKEKHDDM_03695	1.39e-74	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKEKHDDM_03696	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MKEKHDDM_03697	1.41e-284	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MKEKHDDM_03698	6.93e-236	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MKEKHDDM_03699	6.53e-58	ywjC	-	-	-	-	-	-	-
MKEKHDDM_03700	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKEKHDDM_03701	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKEKHDDM_03702	2.04e-134	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKEKHDDM_03703	1.45e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MKEKHDDM_03704	8.93e-124	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MKEKHDDM_03705	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MKEKHDDM_03706	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKEKHDDM_03707	1.44e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MKEKHDDM_03708	1.45e-176	ywiC	-	-	S	-	-	-	YwiC-like protein
MKEKHDDM_03709	7.71e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MKEKHDDM_03710	1.05e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKEKHDDM_03711	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MKEKHDDM_03712	1.14e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03713	1.52e-302	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MKEKHDDM_03714	7.41e-272	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MKEKHDDM_03715	5.77e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKEKHDDM_03717	9.15e-41	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
MKEKHDDM_03718	2.41e-45	-	-	-	-	-	-	-	-
MKEKHDDM_03719	1.18e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MKEKHDDM_03721	5.95e-101	-	-	-	CP	-	-	-	Membrane
MKEKHDDM_03724	9.99e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MKEKHDDM_03725	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKEKHDDM_03726	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKEKHDDM_03727	1.05e-106	-	-	-	-	-	-	-	-
MKEKHDDM_03728	3.32e-124	ywhD	-	-	S	-	-	-	YwhD family
MKEKHDDM_03729	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
MKEKHDDM_03730	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MKEKHDDM_03731	3.42e-92	ywhA	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03732	5.69e-315	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
MKEKHDDM_03733	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MKEKHDDM_03734	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MKEKHDDM_03735	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MKEKHDDM_03736	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MKEKHDDM_03737	5.36e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MKEKHDDM_03738	4.59e-121	-	-	-	S	-	-	-	membrane
MKEKHDDM_03739	8.51e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_03740	1.03e-215	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MKEKHDDM_03743	2.33e-238	-	-	-	-	-	-	-	-
MKEKHDDM_03745	3.72e-203	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MKEKHDDM_03746	2.25e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MKEKHDDM_03747	8.77e-216	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MKEKHDDM_03748	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MKEKHDDM_03749	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MKEKHDDM_03750	2.94e-181	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MKEKHDDM_03751	2.58e-296	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MKEKHDDM_03752	8.14e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MKEKHDDM_03753	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MKEKHDDM_03754	8.05e-181	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKEKHDDM_03755	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MKEKHDDM_03756	5.69e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MKEKHDDM_03757	2.25e-283	ywfA	-	-	EGP	-	-	-	-transporter
MKEKHDDM_03758	8.47e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MKEKHDDM_03759	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKEKHDDM_03760	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MKEKHDDM_03761	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKEKHDDM_03762	3.15e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKEKHDDM_03763	6.37e-77	-	-	-	-	-	-	-	-
MKEKHDDM_03764	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MKEKHDDM_03765	1.16e-208	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKEKHDDM_03766	3.7e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKEKHDDM_03767	6.9e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKEKHDDM_03768	1.7e-234	spsG	-	-	M	-	-	-	Spore Coat
MKEKHDDM_03769	1.01e-171	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MKEKHDDM_03770	1.01e-273	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MKEKHDDM_03771	1.92e-205	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MKEKHDDM_03772	4.35e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MKEKHDDM_03773	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MKEKHDDM_03774	9.06e-184	spsA	-	-	M	-	-	-	Spore Coat
MKEKHDDM_03775	6.51e-88	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MKEKHDDM_03776	1.41e-72	ywdK	-	-	S	-	-	-	small membrane protein
MKEKHDDM_03777	3.96e-293	ywdJ	-	-	F	-	-	-	Xanthine uracil
MKEKHDDM_03778	1.57e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MKEKHDDM_03779	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKEKHDDM_03780	1.34e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MKEKHDDM_03782	2e-115	ywdD	-	-	-	-	-	-	-
MKEKHDDM_03783	1.6e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MKEKHDDM_03784	1.68e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKEKHDDM_03785	3.52e-26	ywdA	-	-	-	-	-	-	-
MKEKHDDM_03786	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKEKHDDM_03787	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_03788	1.57e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKEKHDDM_03790	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKEKHDDM_03791	1.64e-236	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKEKHDDM_03792	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MKEKHDDM_03793	3.11e-270	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MKEKHDDM_03794	1.71e-105	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MKEKHDDM_03795	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MKEKHDDM_03796	8.22e-85	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKEKHDDM_03797	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKEKHDDM_03798	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKEKHDDM_03799	3.67e-227	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MKEKHDDM_03800	5.74e-48	ydaS	-	-	S	-	-	-	membrane
MKEKHDDM_03801	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MKEKHDDM_03802	6.91e-273	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKEKHDDM_03803	1.71e-81	gtcA	-	-	S	-	-	-	GtrA-like protein
MKEKHDDM_03804	6.43e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKEKHDDM_03806	7.5e-168	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MKEKHDDM_03807	4.9e-172	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
MKEKHDDM_03808	5.99e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKEKHDDM_03809	2.19e-309	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MKEKHDDM_03810	2.76e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKEKHDDM_03811	2.62e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKEKHDDM_03812	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_03813	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MKEKHDDM_03814	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MKEKHDDM_03815	2.61e-37	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MKEKHDDM_03816	4.47e-178	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MKEKHDDM_03817	2.54e-212	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MKEKHDDM_03818	3.08e-286	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MKEKHDDM_03819	1.76e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MKEKHDDM_03820	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKEKHDDM_03821	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKEKHDDM_03822	2.56e-208	gspA	-	-	M	-	-	-	General stress
MKEKHDDM_03823	4.35e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MKEKHDDM_03824	1.07e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MKEKHDDM_03825	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MKEKHDDM_03826	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_03827	1.04e-292	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MKEKHDDM_03828	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKEKHDDM_03829	3.76e-290	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKEKHDDM_03830	1.35e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MKEKHDDM_03831	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKEKHDDM_03832	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_03833	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKEKHDDM_03834	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MKEKHDDM_03835	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MKEKHDDM_03836	5.36e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MKEKHDDM_03837	7.77e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_03838	9.74e-231	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKEKHDDM_03839	9.23e-214	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKEKHDDM_03840	1.91e-78	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MKEKHDDM_03841	6.03e-289	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKEKHDDM_03842	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_03843	7.89e-66	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_03844	7.31e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKEKHDDM_03845	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKEKHDDM_03846	9.95e-211	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MKEKHDDM_03847	2.15e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKEKHDDM_03848	8.82e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MKEKHDDM_03849	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKEKHDDM_03850	7.89e-246	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MKEKHDDM_03851	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MKEKHDDM_03852	1.46e-199	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKEKHDDM_03853	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MKEKHDDM_03854	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MKEKHDDM_03855	3.07e-239	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MKEKHDDM_03856	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MKEKHDDM_03857	1.58e-287	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MKEKHDDM_03858	1.2e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MKEKHDDM_03859	2.51e-259	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKEKHDDM_03860	6.26e-216	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MKEKHDDM_03861	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKEKHDDM_03862	8.94e-119	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MKEKHDDM_03863	6.54e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKEKHDDM_03864	2.82e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MKEKHDDM_03867	6.11e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MKEKHDDM_03868	2.8e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MKEKHDDM_03869	3.73e-206	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MKEKHDDM_03870	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKEKHDDM_03871	3.75e-126	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MKEKHDDM_03872	2.68e-67	yxiS	-	-	-	-	-	-	-
MKEKHDDM_03873	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKEKHDDM_03874	2.33e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MKEKHDDM_03875	3.44e-186	bglS	-	-	M	-	-	-	licheninase activity
MKEKHDDM_03876	3.41e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKEKHDDM_03877	8.61e-281	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MKEKHDDM_03878	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MKEKHDDM_03880	9.29e-28	-	-	-	-	-	-	-	-
MKEKHDDM_03881	1.28e-11	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MKEKHDDM_03882	3.1e-131	-	-	-	-	-	-	-	-
MKEKHDDM_03883	3.33e-101	-	-	-	-	-	-	-	-
MKEKHDDM_03887	7.82e-82	yxiG	-	-	-	-	-	-	-
MKEKHDDM_03889	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MKEKHDDM_03890	3.83e-257	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MKEKHDDM_03891	8.44e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MKEKHDDM_03892	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MKEKHDDM_03893	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKEKHDDM_03894	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKEKHDDM_03895	6.01e-124	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
MKEKHDDM_03896	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MKEKHDDM_03897	9.97e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MKEKHDDM_03898	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MKEKHDDM_03899	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKEKHDDM_03900	1.29e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MKEKHDDM_03901	2.04e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MKEKHDDM_03902	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKEKHDDM_03903	1.57e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MKEKHDDM_03904	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKEKHDDM_03905	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKEKHDDM_03906	1.66e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKEKHDDM_03907	6.65e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKEKHDDM_03910	2.06e-42	yxeE	-	-	-	-	-	-	-
MKEKHDDM_03911	5.09e-35	yxeD	-	-	-	-	-	-	-
MKEKHDDM_03912	8.01e-46	-	-	-	-	-	-	-	-
MKEKHDDM_03913	2.39e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKEKHDDM_03914	4.03e-75	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MKEKHDDM_03915	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKEKHDDM_03916	3.28e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_03917	6.53e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03918	4.84e-161	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03919	0.0	-	-	-	T	-	-	-	Histidine kinase
MKEKHDDM_03920	5.25e-175	yvrH	-	-	T	-	-	-	Transcriptional regulator
MKEKHDDM_03921	6.2e-210	-	-	-	V	ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKEKHDDM_03922	1.36e-167	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
MKEKHDDM_03923	1.89e-170	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKEKHDDM_03924	3.3e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MKEKHDDM_03925	5.94e-201	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MKEKHDDM_03926	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MKEKHDDM_03927	5.4e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MKEKHDDM_03928	1.82e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MKEKHDDM_03929	3.96e-224	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MKEKHDDM_03930	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MKEKHDDM_03931	6.88e-232	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MKEKHDDM_03932	1.78e-202	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MKEKHDDM_03933	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKEKHDDM_03934	7.11e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKEKHDDM_03935	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MKEKHDDM_03936	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKEKHDDM_03937	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MKEKHDDM_03939	3.98e-191	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKEKHDDM_03940	1.07e-131	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKEKHDDM_03941	2.38e-254	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03942	1.29e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MKEKHDDM_03943	2.3e-276	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKEKHDDM_03944	9.34e-317	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKEKHDDM_03945	2.25e-187	yxaL	-	-	S	-	-	-	PQQ-like domain
MKEKHDDM_03946	1.19e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MKEKHDDM_03947	7.01e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKEKHDDM_03948	9.77e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKEKHDDM_03949	9.49e-98	yxaI	-	-	S	-	-	-	membrane protein domain
MKEKHDDM_03950	5.68e-164	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
MKEKHDDM_03951	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MKEKHDDM_03952	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MKEKHDDM_03953	4.61e-291	-	-	-	S	-	-	-	Fic/DOC family
MKEKHDDM_03954	5.26e-314	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MKEKHDDM_03955	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MKEKHDDM_03956	9.14e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MKEKHDDM_03957	2.23e-196	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MKEKHDDM_03958	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MKEKHDDM_03959	1.16e-122	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MKEKHDDM_03960	4.54e-241	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKEKHDDM_03961	1.99e-237	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MKEKHDDM_03962	2.61e-26	-	-	-	-	-	-	-	-
MKEKHDDM_03963	1.48e-157	-	-	-	S	-	-	-	AIPR protein
MKEKHDDM_03964	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKEKHDDM_03968	3.99e-273	yycP	-	-	-	-	-	-	-
MKEKHDDM_03969	7.96e-170	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKEKHDDM_03970	1.11e-235	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MKEKHDDM_03971	1.02e-113	yycN	-	-	K	-	-	-	Acetyltransferase
MKEKHDDM_03973	6.13e-258	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MKEKHDDM_03974	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MKEKHDDM_03975	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKEKHDDM_03976	6.81e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MKEKHDDM_03977	3.8e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MKEKHDDM_03978	2.69e-57	sdpR	-	-	K	-	-	-	transcriptional
MKEKHDDM_03979	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MKEKHDDM_03980	2.62e-188	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
MKEKHDDM_03981	0.0	-	-	-	S	-	-	-	ABC transporter
MKEKHDDM_03982	6.06e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
MKEKHDDM_03983	0.0	-	-	-	-	-	-	-	-
MKEKHDDM_03984	2.12e-239	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MKEKHDDM_03985	1.42e-307	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKEKHDDM_03986	1.97e-12	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03987	1.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKEKHDDM_03988	1.98e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MKEKHDDM_03989	1.98e-194	yycI	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03990	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_03991	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKEKHDDM_03992	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKEKHDDM_03997	1.55e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKEKHDDM_03998	2.51e-91	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_03999	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MKEKHDDM_04000	2.21e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MKEKHDDM_04002	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
MKEKHDDM_04003	1.26e-305	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MKEKHDDM_04004	3.69e-258	-	-	-	S	-	-	-	Ecdysteroid kinase
MKEKHDDM_04005	3.12e-295	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
MKEKHDDM_04006	2e-300	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MKEKHDDM_04007	1.25e-156	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MKEKHDDM_04008	4.67e-155	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
MKEKHDDM_04009	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKEKHDDM_04010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKEKHDDM_04011	2.48e-204	yybS	-	-	S	-	-	-	membrane
MKEKHDDM_04013	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MKEKHDDM_04014	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_04015	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MKEKHDDM_04016	4.13e-197	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKEKHDDM_04017	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MKEKHDDM_04018	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MKEKHDDM_04019	1.33e-149	-	-	-	K	-	-	-	FCD domain
MKEKHDDM_04020	2.25e-116	-	-	-	S	-	-	-	PFAM DinB family protein
MKEKHDDM_04021	1.41e-205	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKEKHDDM_04022	2.06e-202	-	-	-	K	-	-	-	LysR substrate binding domain
MKEKHDDM_04023	1.13e-129	-	-	-	E	-	-	-	LysE type translocator
MKEKHDDM_04024	1.94e-74	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MKEKHDDM_04025	1.7e-148	ydgI	-	-	C	-	-	-	nitroreductase
MKEKHDDM_04026	9.65e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MKEKHDDM_04027	1.38e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKEKHDDM_04028	7.54e-99	yybA	-	-	K	-	-	-	transcriptional
MKEKHDDM_04029	4.11e-95	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKEKHDDM_04030	6.47e-209	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
MKEKHDDM_04031	2.02e-88	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MKEKHDDM_04032	4.21e-212	-	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_04033	1.32e-182	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKEKHDDM_04034	4.3e-312	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKEKHDDM_04035	1.1e-163	-	-	-	EG	-	-	-	EamA-like transporter family
MKEKHDDM_04036	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MKEKHDDM_04037	3.6e-211	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MKEKHDDM_04038	1.88e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MKEKHDDM_04039	8.1e-87	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKEKHDDM_04040	6.9e-232	ccpB	-	-	K	-	-	-	Transcriptional regulator
MKEKHDDM_04041	1.98e-185	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MKEKHDDM_04042	5.84e-129	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKEKHDDM_04043	4.41e-137	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MKEKHDDM_04044	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKEKHDDM_04045	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKEKHDDM_04046	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MKEKHDDM_04047	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKEKHDDM_04048	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKEKHDDM_04049	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_04050	1.67e-225	yyaD	-	-	S	-	-	-	Membrane
MKEKHDDM_04051	8.15e-109	yhhY	-	-	K	-	-	-	FR47-like protein
MKEKHDDM_04052	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MKEKHDDM_04053	1.43e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MKEKHDDM_04054	1.18e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MKEKHDDM_04055	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MKEKHDDM_04056	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MKEKHDDM_04057	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKEKHDDM_04058	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKEKHDDM_04059	6.6e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MKEKHDDM_04060	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKEKHDDM_04061	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKEKHDDM_04062	7.83e-05	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MKEKHDDM_04065	7.34e-12	-	-	-	-	-	-	-	-
MKEKHDDM_04067	4.58e-12	-	-	-	S	-	-	-	YvrJ protein family
MKEKHDDM_04068	1.35e-48	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	COG1191 DNA-directed RNA polymerase specialized sigma subunit
MKEKHDDM_04069	1.88e-15	-	-	-	-	-	-	-	-
MKEKHDDM_04074	3.76e-56	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MKEKHDDM_04076	3.33e-126	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
MKEKHDDM_04078	6.8e-28	-	-	-	S	ko:K06419,ko:K06420	-	ko00000	spore protein
MKEKHDDM_04082	8.38e-65	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKEKHDDM_04092	4.17e-05	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	thymidylate kinase
MKEKHDDM_04093	4.63e-62	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MKEKHDDM_04099	2.76e-05	-	-	-	K	-	-	-	Belongs to the ParB family
MKEKHDDM_04104	1.11e-22	-	-	-	S	-	-	-	protein conserved in bacteria
MKEKHDDM_04110	1.06e-64	-	-	-	U	-	-	-	Protein of unknown function DUF262
MKEKHDDM_04122	2e-50	-	-	-	S	-	-	-	Macro domain
MKEKHDDM_04127	3.2e-75	-	-	-	-	-	-	-	-
MKEKHDDM_04128	4.72e-139	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKEKHDDM_04130	9.71e-71	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKEKHDDM_04131	1.66e-178	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
MKEKHDDM_04150	4.1e-151	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKEKHDDM_04155	4.06e-23	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MKEKHDDM_04157	3.21e-59	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MKEKHDDM_04175	4.27e-11	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MKEKHDDM_04196	1.41e-27	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKEKHDDM_04207	4.98e-23	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
MKEKHDDM_04212	5.12e-26	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKEKHDDM_04214	2.67e-40	ymaB	-	-	S	-	-	-	DNA mismatch repair protein MutT
MKEKHDDM_04215	1.75e-31	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_04216	1.1e-169	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKEKHDDM_04217	2.69e-06	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MKEKHDDM_04219	2.28e-60	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	type II secretion system protein E
MKEKHDDM_04223	2.15e-32	-	-	-	N	-	-	-	domain, Protein
MKEKHDDM_04226	9.11e-28	-	-	-	-	-	-	-	-
MKEKHDDM_04231	1.23e-172	-	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	COG4962 Flp pilus assembly protein, ATPase CpaF
MKEKHDDM_04232	3.21e-106	-	-	-	D	-	-	-	bacterial-type flagellum organization
MKEKHDDM_04235	4.28e-213	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKEKHDDM_04237	1.96e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF1273)
MKEKHDDM_04238	4.45e-07	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MKEKHDDM_04249	2.48e-34	acmA	3.2.1.17, 3.2.1.96	-	MNU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Lysozyme subfamily 2
MKEKHDDM_04250	1.12e-115	-	-	-	S	-	-	-	Predicted nucleotidyltransferase
MKEKHDDM_04251	1.39e-89	-	-	-	F	-	-	-	protein conserved in bacteria
MKEKHDDM_04255	3.88e-17	-	-	-	H	-	-	-	ThiF family
MKEKHDDM_04273	0.000328	-	-	-	S	-	-	-	YopX protein
MKEKHDDM_04285	2.32e-275	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKEKHDDM_04304	1.5e-57	-	-	-	L	-	-	-	UvrD-like helicase C-terminal domain
MKEKHDDM_04313	1.21e-41	-	-	-	L	-	-	-	DNA methylase
MKEKHDDM_04329	5.97e-61	-	-	-	-	-	-	-	-
MKEKHDDM_04342	7.31e-81	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MKEKHDDM_04347	7.6e-104	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MKEKHDDM_04352	5.46e-05	-	-	-	-	-	-	-	-
MKEKHDDM_04360	6.72e-46	pilT-1	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MKEKHDDM_04366	5.8e-111	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
MKEKHDDM_04368	4.46e-90	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MKEKHDDM_04374	8.04e-14	rok	-	-	S	-	-	-	Repressor of ComK
MKEKHDDM_04375	5.07e-65	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKEKHDDM_04377	9.21e-53	-	-	-	L	-	-	-	Site-specific recombinase, phage integrase family
MKEKHDDM_04383	2.95e-148	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
MKEKHDDM_04387	1.13e-45	nucH	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	Staphylococcal nuclease homologues
MKEKHDDM_04390	9.26e-111	-	-	-	L	-	-	-	Domain of unknown function (DUF1738)
MKEKHDDM_04403	3.12e-195	-	-	-	S	-	-	-	damaged DNA binding
MKEKHDDM_04404	1.03e-39	-	-	-	-	-	-	-	-
MKEKHDDM_04410	3.79e-192	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
MKEKHDDM_04411	4.04e-53	-	-	-	K	-	-	-	COG0457 FOG TPR repeat
MKEKHDDM_04413	1.91e-07	-	-	-	K	ko:K22299	-	ko00000,ko03000	Helix-turn-helix domain
MKEKHDDM_04417	2.47e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MKEKHDDM_04420	1.32e-264	-	-	-	M	-	-	-	domain protein
MKEKHDDM_04424	1.73e-132	-	-	-	NU	ko:K02283	-	ko00000,ko02035,ko02044	Secretion system protein
MKEKHDDM_04425	1.61e-99	-	-	-	-	-	-	-	-
MKEKHDDM_04426	1.87e-69	-	-	-	-	-	-	-	-
MKEKHDDM_04427	1.24e-37	-	-	-	-	-	-	-	-
MKEKHDDM_04436	2.96e-209	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MKEKHDDM_04437	1.22e-89	-	-	-	S	-	-	-	domain, Protein
MKEKHDDM_04439	7.29e-40	-	-	-	-	-	-	-	-
MKEKHDDM_04440	2.44e-212	-	-	-	S	-	-	-	AAA-like domain
MKEKHDDM_04442	1.04e-67	yddH	-	-	M	-	-	-	Lysozyme-like