ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IHONEDMF_00001 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHONEDMF_00004 0.0 - - - L - - - PIF1-like helicase
IHONEDMF_00005 2e-205 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IHONEDMF_00006 1.91e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
IHONEDMF_00008 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
IHONEDMF_00009 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IHONEDMF_00010 5.03e-259 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
IHONEDMF_00011 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
IHONEDMF_00012 1.11e-79 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
IHONEDMF_00013 9.44e-234 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHONEDMF_00014 1.17e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHONEDMF_00015 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IHONEDMF_00017 3.38e-252 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
IHONEDMF_00018 2.74e-209 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
IHONEDMF_00019 9.51e-240 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IHONEDMF_00020 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
IHONEDMF_00021 1.52e-145 - - - - - - - -
IHONEDMF_00022 1.6e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
IHONEDMF_00023 1.68e-190 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IHONEDMF_00024 0.0 - - - JKL - - - helicase superfamily c-terminal domain
IHONEDMF_00025 1.23e-210 - - - EG - - - EamA-like transporter family
IHONEDMF_00026 2.85e-05 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00027 1.87e-182 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IHONEDMF_00028 2.76e-189 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
IHONEDMF_00030 1.3e-36 - - - L - - - Transposase
IHONEDMF_00031 1.8e-271 - - - S - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00032 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
IHONEDMF_00033 7.9e-48 - - - C - - - Aldo/keto reductase family
IHONEDMF_00034 1.17e-95 - - - EGP - - - Major facilitator superfamily
IHONEDMF_00036 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IHONEDMF_00037 0.0 - - - S - - - ATPases associated with a variety of cellular activities
IHONEDMF_00038 6.7e-74 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
IHONEDMF_00039 2.95e-201 - - - I - - - alpha/beta hydrolase fold
IHONEDMF_00040 1.2e-141 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
IHONEDMF_00042 7.1e-70 - - - S - - - DUF218 domain
IHONEDMF_00043 9.06e-23 - - - S - - - Protein of unknown function (DUF979)
IHONEDMF_00044 3.55e-147 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHONEDMF_00046 1.72e-76 - - - - - - - -
IHONEDMF_00047 4.18e-45 - - - - - - - -
IHONEDMF_00048 1.9e-73 - - - M - - - domain, Protein
IHONEDMF_00049 1.42e-18 - - - M - - - domain, Protein
IHONEDMF_00050 3.61e-50 - - - S - - - Protein of unknown function (DUF3791)
IHONEDMF_00051 3.98e-116 - - - S - - - Protein of unknown function (DUF3990)
IHONEDMF_00053 1.51e-87 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
IHONEDMF_00054 8.06e-34 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
IHONEDMF_00056 3.67e-126 - - - S - - - Domain of unknown function (DUF4825)
IHONEDMF_00057 2.83e-58 - - - K - - - response regulator
IHONEDMF_00058 8.74e-62 - - - T - - - response regulator
IHONEDMF_00059 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
IHONEDMF_00060 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
IHONEDMF_00061 2.66e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
IHONEDMF_00062 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
IHONEDMF_00063 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHONEDMF_00064 3.21e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHONEDMF_00065 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IHONEDMF_00066 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHONEDMF_00067 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
IHONEDMF_00068 5.78e-268 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHONEDMF_00069 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
IHONEDMF_00070 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
IHONEDMF_00071 2.26e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_00072 3.97e-295 - - - M - - - Glycosyl transferase family 21
IHONEDMF_00073 0.0 - - - S - - - AI-2E family transporter
IHONEDMF_00074 5.42e-227 - - - M - - - Glycosyltransferase like family 2
IHONEDMF_00075 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
IHONEDMF_00078 2.03e-110 - - - S - - - Domain of unknown function (DUF4190)
IHONEDMF_00079 1.14e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IHONEDMF_00080 2.9e-224 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHONEDMF_00082 7.77e-24 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
IHONEDMF_00083 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
IHONEDMF_00084 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
IHONEDMF_00085 8.2e-118 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
IHONEDMF_00086 1.65e-232 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
IHONEDMF_00087 2.44e-302 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IHONEDMF_00088 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
IHONEDMF_00089 3.34e-131 - - - - - - - -
IHONEDMF_00090 7.07e-231 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
IHONEDMF_00091 1.93e-139 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_00092 4.81e-236 - - - - - - - -
IHONEDMF_00093 2e-09 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
IHONEDMF_00094 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
IHONEDMF_00095 1.94e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
IHONEDMF_00096 5.06e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00097 1.86e-31 - - - E - - - Branched-chain amino acid transport protein (AzlD)
IHONEDMF_00098 4.43e-250 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
IHONEDMF_00099 5.73e-125 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
IHONEDMF_00100 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
IHONEDMF_00101 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHONEDMF_00102 8.79e-94 - - - O - - - OsmC-like protein
IHONEDMF_00103 1.08e-243 - - - T - - - Universal stress protein family
IHONEDMF_00104 5.95e-147 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
IHONEDMF_00105 9.66e-228 - - - S - - - CHAP domain
IHONEDMF_00106 1.28e-275 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHONEDMF_00107 4.6e-53 - - - - - - - -
IHONEDMF_00108 9.24e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
IHONEDMF_00109 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
IHONEDMF_00110 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHONEDMF_00111 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IHONEDMF_00112 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IHONEDMF_00114 7.45e-278 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
IHONEDMF_00115 0.0 - - - S - - - Domain of unknown function (DUF4037)
IHONEDMF_00116 3.89e-145 - - - S - - - Protein of unknown function (DUF4125)
IHONEDMF_00117 1.3e-195 - - - - - - - -
IHONEDMF_00118 0.0 pspC - - KT - - - PspC domain
IHONEDMF_00119 0.0 tcsS3 - - KT - - - PspC domain
IHONEDMF_00120 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_00121 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHONEDMF_00123 1.43e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IHONEDMF_00124 1.07e-239 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
IHONEDMF_00125 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHONEDMF_00126 1.06e-121 - - - - - - - -
IHONEDMF_00128 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
IHONEDMF_00130 2.7e-301 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHONEDMF_00131 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
IHONEDMF_00132 1.12e-270 - - - I - - - Diacylglycerol kinase catalytic domain
IHONEDMF_00133 5.06e-198 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
IHONEDMF_00134 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
IHONEDMF_00135 4.73e-05 - - - O ko:K18546 - ko00000,ko01000,ko01002 Peptidase s1 and s6 chymotrypsin hap
IHONEDMF_00136 4.43e-57 - - - M - - - Spy0128-like isopeptide containing domain
IHONEDMF_00137 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IHONEDMF_00138 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHONEDMF_00139 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
IHONEDMF_00140 4.34e-261 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHONEDMF_00141 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHONEDMF_00142 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
IHONEDMF_00143 6.9e-142 - - - - - - - -
IHONEDMF_00144 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHONEDMF_00145 1.78e-304 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
IHONEDMF_00146 2.85e-302 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHONEDMF_00147 8.76e-124 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHONEDMF_00148 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHONEDMF_00149 1.16e-241 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IHONEDMF_00150 4.44e-225 - - - - - - - -
IHONEDMF_00151 4.97e-186 tnp3503b - - L - - - Transposase and inactivated derivatives
IHONEDMF_00153 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
IHONEDMF_00154 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
IHONEDMF_00155 3.35e-220 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHONEDMF_00156 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
IHONEDMF_00157 2.18e-94 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IHONEDMF_00158 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHONEDMF_00159 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHONEDMF_00160 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHONEDMF_00161 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IHONEDMF_00162 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHONEDMF_00163 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHONEDMF_00164 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHONEDMF_00165 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IHONEDMF_00166 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
IHONEDMF_00167 2.04e-149 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHONEDMF_00168 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHONEDMF_00169 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHONEDMF_00170 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHONEDMF_00171 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHONEDMF_00172 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHONEDMF_00173 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHONEDMF_00174 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHONEDMF_00175 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHONEDMF_00176 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IHONEDMF_00177 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHONEDMF_00178 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHONEDMF_00179 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHONEDMF_00180 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHONEDMF_00181 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHONEDMF_00182 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHONEDMF_00183 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IHONEDMF_00184 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHONEDMF_00185 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IHONEDMF_00186 1.34e-74 - - - S - - - YwiC-like protein
IHONEDMF_00187 3.29e-114 - - - S - - - YwiC-like protein
IHONEDMF_00188 9.78e-202 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IHONEDMF_00189 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
IHONEDMF_00190 2.39e-295 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IHONEDMF_00191 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
IHONEDMF_00192 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IHONEDMF_00193 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHONEDMF_00194 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
IHONEDMF_00195 4.17e-152 - - - - - - - -
IHONEDMF_00196 5.69e-147 yigZ - - S - - - Uncharacterized protein family UPF0029
IHONEDMF_00197 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
IHONEDMF_00199 1.87e-307 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHONEDMF_00200 3.46e-286 dapC - - E - - - Aminotransferase class I and II
IHONEDMF_00201 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
IHONEDMF_00202 1.91e-280 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
IHONEDMF_00203 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
IHONEDMF_00207 1.01e-75 - - - KLT - - - Associated with various cellular activities
IHONEDMF_00208 3.21e-166 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IHONEDMF_00209 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHONEDMF_00210 2.25e-266 - - - - - - - -
IHONEDMF_00211 1.2e-191 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IHONEDMF_00212 5.69e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
IHONEDMF_00213 1.88e-51 - - - S - - - Putative regulatory protein
IHONEDMF_00214 2.46e-140 - - - NO - - - SAF
IHONEDMF_00215 2.87e-56 - - - - - - - -
IHONEDMF_00216 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
IHONEDMF_00217 0.0 - - - T - - - Forkhead associated domain
IHONEDMF_00219 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHONEDMF_00220 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHONEDMF_00221 2.82e-232 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
IHONEDMF_00222 0.0 - - - G - - - BNR repeat-like domain
IHONEDMF_00224 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
IHONEDMF_00226 7.39e-219 - - - S - - - Protein conserved in bacteria
IHONEDMF_00227 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHONEDMF_00228 6.61e-234 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IHONEDMF_00229 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IHONEDMF_00230 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
IHONEDMF_00231 1.82e-163 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IHONEDMF_00232 2.71e-313 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
IHONEDMF_00233 2.2e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHONEDMF_00234 3.6e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHONEDMF_00235 2.63e-142 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IHONEDMF_00236 1.75e-309 - - - EGP - - - Major Facilitator Superfamily
IHONEDMF_00237 1.38e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHONEDMF_00238 6.38e-235 - - - L - - - Excalibur calcium-binding domain
IHONEDMF_00239 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IHONEDMF_00240 1.52e-123 - - - D - - - nuclear chromosome segregation
IHONEDMF_00241 2.23e-164 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHONEDMF_00242 1.28e-185 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IHONEDMF_00243 5.08e-237 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
IHONEDMF_00244 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
IHONEDMF_00245 6.99e-122 - - - L - - - Transposase and inactivated derivatives IS30 family
IHONEDMF_00246 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
IHONEDMF_00247 7.29e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
IHONEDMF_00248 2.85e-127 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IHONEDMF_00249 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHONEDMF_00250 8.5e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHONEDMF_00251 6.87e-92 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
IHONEDMF_00252 0.0 - - - S - - - Predicted membrane protein (DUF2207)
IHONEDMF_00253 1.52e-122 lemA - - S ko:K03744 - ko00000 LemA family
IHONEDMF_00254 2.56e-55 - - - K - - - purine nucleotide biosynthetic process
IHONEDMF_00255 3.32e-194 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
IHONEDMF_00256 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IHONEDMF_00257 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHONEDMF_00258 6.34e-155 - - - - - - - -
IHONEDMF_00259 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
IHONEDMF_00261 4.39e-209 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
IHONEDMF_00262 6.53e-127 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHONEDMF_00263 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
IHONEDMF_00264 0.0 pccB - - I - - - Carboxyl transferase domain
IHONEDMF_00265 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IHONEDMF_00266 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IHONEDMF_00267 4.75e-196 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
IHONEDMF_00268 0.0 - - - - - - - -
IHONEDMF_00269 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
IHONEDMF_00270 3.84e-169 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IHONEDMF_00271 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IHONEDMF_00272 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHONEDMF_00273 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHONEDMF_00274 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHONEDMF_00275 1.14e-191 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHONEDMF_00276 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHONEDMF_00277 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHONEDMF_00279 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IHONEDMF_00280 1.2e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IHONEDMF_00282 1.11e-59 - - - - - - - -
IHONEDMF_00283 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
IHONEDMF_00284 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IHONEDMF_00285 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IHONEDMF_00287 2.85e-134 mntP - - P - - - Probably functions as a manganese efflux pump
IHONEDMF_00288 5.6e-170 - - - - - - - -
IHONEDMF_00289 4.39e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
IHONEDMF_00290 8.16e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHONEDMF_00291 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
IHONEDMF_00292 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHONEDMF_00293 0.0 - - - S - - - domain protein
IHONEDMF_00294 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
IHONEDMF_00295 3.12e-117 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
IHONEDMF_00296 8.68e-299 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
IHONEDMF_00297 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IHONEDMF_00298 0.0 - - - H - - - Flavin containing amine oxidoreductase
IHONEDMF_00299 1.32e-68 - - - S - - - Protein of unknown function (DUF2469)
IHONEDMF_00300 1.38e-251 - - - J - - - Acetyltransferase (GNAT) domain
IHONEDMF_00301 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHONEDMF_00302 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHONEDMF_00303 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHONEDMF_00304 3.36e-108 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_00305 3.77e-81 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_00306 6.49e-212 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
IHONEDMF_00307 1.41e-62 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHONEDMF_00308 1.78e-64 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHONEDMF_00309 1.45e-297 rmuC - - S ko:K09760 - ko00000 RmuC family
IHONEDMF_00310 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
IHONEDMF_00311 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
IHONEDMF_00312 0.0 - - - S ko:K03688 - ko00000 ABC1 family
IHONEDMF_00313 3.15e-44 - - - S - - - granule-associated protein
IHONEDMF_00314 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
IHONEDMF_00315 0.0 murE - - M - - - Domain of unknown function (DUF1727)
IHONEDMF_00316 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IHONEDMF_00317 0.0 dinF - - V - - - MatE
IHONEDMF_00319 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
IHONEDMF_00320 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
IHONEDMF_00321 3.48e-304 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
IHONEDMF_00322 2.48e-276 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHONEDMF_00324 1.17e-172 icaR - - K - - - Bacterial regulatory proteins, tetR family
IHONEDMF_00325 1.96e-254 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
IHONEDMF_00326 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
IHONEDMF_00327 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
IHONEDMF_00329 8.22e-25 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IHONEDMF_00330 2.43e-90 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IHONEDMF_00331 2.01e-107 - - - - - - - -
IHONEDMF_00332 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
IHONEDMF_00333 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00334 2.29e-106 - - - K - - - Winged helix DNA-binding domain
IHONEDMF_00335 0.0 - - - M - - - LPXTG cell wall anchor motif
IHONEDMF_00336 0.0 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
IHONEDMF_00337 4.25e-229 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IHONEDMF_00339 3.47e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IHONEDMF_00340 2.27e-307 - - - S - - - Putative ABC-transporter type IV
IHONEDMF_00341 2.24e-103 - - - - - - - -
IHONEDMF_00342 5.23e-45 - - - Q - - - phosphatase activity
IHONEDMF_00343 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
IHONEDMF_00344 6.37e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
IHONEDMF_00345 1.2e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IHONEDMF_00346 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHONEDMF_00347 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
IHONEDMF_00348 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
IHONEDMF_00349 8.08e-103 - - - S - - - FMN_bind
IHONEDMF_00350 2.6e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00351 8.23e-275 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IHONEDMF_00352 3.23e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
IHONEDMF_00353 5.03e-295 - - - S - - - Predicted membrane protein (DUF2318)
IHONEDMF_00354 3.94e-149 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
IHONEDMF_00355 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
IHONEDMF_00356 8.59e-26 - - - G - - - MFS/sugar transport protein
IHONEDMF_00357 2.9e-256 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHONEDMF_00358 9.2e-70 - - - S - - - Fic/DOC family
IHONEDMF_00359 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHONEDMF_00360 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
IHONEDMF_00361 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_00362 3.65e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IHONEDMF_00363 2.08e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHONEDMF_00364 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHONEDMF_00365 3.03e-243 - - - I - - - PAP2 superfamily
IHONEDMF_00366 0.0 - - - M - - - PA domain
IHONEDMF_00367 2.69e-174 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
IHONEDMF_00368 1.48e-294 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
IHONEDMF_00369 0.0 pbp5 - - M - - - Transglycosylase
IHONEDMF_00370 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHONEDMF_00371 0.0 - - - S - - - Calcineurin-like phosphoesterase
IHONEDMF_00372 9.58e-18 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
IHONEDMF_00373 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
IHONEDMF_00374 1.77e-148 - - - - - - - -
IHONEDMF_00375 7.59e-269 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHONEDMF_00377 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
IHONEDMF_00378 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
IHONEDMF_00379 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHONEDMF_00380 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
IHONEDMF_00381 1.88e-273 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
IHONEDMF_00382 2.09e-72 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
IHONEDMF_00383 3.96e-55 - - - S - - - Protein of unknown function (DUF4244)
IHONEDMF_00384 1.3e-20 - - - NU - - - Type II secretion system (T2SS), protein F
IHONEDMF_00386 8.75e-156 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
IHONEDMF_00387 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
IHONEDMF_00388 5.47e-196 - - - D - - - bacterial-type flagellum organization
IHONEDMF_00390 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IHONEDMF_00391 7.44e-281 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
IHONEDMF_00392 3.53e-128 - - - - - - - -
IHONEDMF_00393 3.15e-75 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IHONEDMF_00394 9.53e-267 - - - S - - - Glycosyltransferase, group 2 family protein
IHONEDMF_00395 0.0 - - - - - - - -
IHONEDMF_00396 0.000146 - - - - - - - -
IHONEDMF_00397 2.41e-37 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
IHONEDMF_00398 1.93e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IHONEDMF_00399 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00400 0.0 - - - H - - - Protein of unknown function (DUF4012)
IHONEDMF_00401 0.0 - - - V - - - ABC transporter permease
IHONEDMF_00402 2.81e-270 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_00403 4.97e-177 - - - T ko:K06950 - ko00000 HD domain
IHONEDMF_00404 2.98e-214 - - - S - - - Glutamine amidotransferase domain
IHONEDMF_00405 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
IHONEDMF_00406 1.57e-236 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
IHONEDMF_00407 0.0 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
IHONEDMF_00409 7.84e-113 - - - K - - - Transcriptional regulator
IHONEDMF_00410 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHONEDMF_00411 7.68e-170 - - - - - - - -
IHONEDMF_00412 1.6e-83 - - - - - - - -
IHONEDMF_00413 2.05e-224 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHONEDMF_00414 1.54e-162 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
IHONEDMF_00416 1.42e-172 - - - S - - - HAD hydrolase, family IA, variant 3
IHONEDMF_00417 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
IHONEDMF_00418 2.15e-300 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
IHONEDMF_00419 5.58e-231 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
IHONEDMF_00420 7.5e-111 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
IHONEDMF_00421 2.23e-235 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
IHONEDMF_00423 3.14e-90 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHONEDMF_00424 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IHONEDMF_00425 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
IHONEDMF_00426 9.58e-244 - - - K - - - Psort location Cytoplasmic, score
IHONEDMF_00429 1.84e-180 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
IHONEDMF_00430 8.75e-90 - - - S - - - Protein of unknown function (DUF4235)
IHONEDMF_00431 1.28e-180 nfrA - - C - - - Nitroreductase family
IHONEDMF_00432 2.45e-61 - - - - - - - -
IHONEDMF_00433 3.82e-230 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
IHONEDMF_00434 4.48e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IHONEDMF_00435 1.28e-277 - - - GK - - - ROK family
IHONEDMF_00436 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
IHONEDMF_00437 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IHONEDMF_00438 3.95e-252 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IHONEDMF_00439 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
IHONEDMF_00440 2.4e-180 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IHONEDMF_00441 5.05e-314 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IHONEDMF_00442 3.2e-47 - - - K - - - Transcriptional regulatory protein, C terminal
IHONEDMF_00443 2.62e-54 - - - K - - - Transcriptional regulatory protein, C terminal
IHONEDMF_00444 8.98e-38 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
IHONEDMF_00445 3.92e-118 - - - - - - - -
IHONEDMF_00446 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IHONEDMF_00447 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHONEDMF_00448 3.85e-233 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
IHONEDMF_00449 3.02e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IHONEDMF_00450 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IHONEDMF_00451 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
IHONEDMF_00452 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHONEDMF_00453 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
IHONEDMF_00454 1.75e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
IHONEDMF_00455 2.44e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IHONEDMF_00456 3.01e-308 - - - V - - - MatE
IHONEDMF_00458 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IHONEDMF_00459 1.88e-183 - - - S - - - Protein of unknown function (DUF1275)
IHONEDMF_00460 1.83e-257 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IHONEDMF_00461 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
IHONEDMF_00462 1.07e-284 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHONEDMF_00463 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHONEDMF_00464 8.17e-204 - - - G - - - Fructosamine kinase
IHONEDMF_00465 8.18e-216 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHONEDMF_00466 2.89e-199 - - - S - - - PAC2 family
IHONEDMF_00470 0.0 - - - - - - - -
IHONEDMF_00473 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHONEDMF_00474 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHONEDMF_00475 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
IHONEDMF_00476 2.79e-176 yebC - - K - - - transcriptional regulatory protein
IHONEDMF_00477 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IHONEDMF_00478 1.83e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHONEDMF_00479 6.91e-259 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHONEDMF_00480 3.73e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
IHONEDMF_00481 4.56e-130 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHONEDMF_00482 2.85e-285 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IHONEDMF_00483 4.72e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IHONEDMF_00484 5.24e-312 - - - - - - - -
IHONEDMF_00485 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IHONEDMF_00486 5.17e-56 - - - - - - - -
IHONEDMF_00487 9.88e-167 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IHONEDMF_00488 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IHONEDMF_00489 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IHONEDMF_00490 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IHONEDMF_00491 2.26e-210 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IHONEDMF_00492 4.57e-246 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHONEDMF_00493 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
IHONEDMF_00494 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
IHONEDMF_00495 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
IHONEDMF_00496 1.1e-151 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHONEDMF_00497 4.59e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
IHONEDMF_00498 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
IHONEDMF_00499 3.22e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
IHONEDMF_00500 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
IHONEDMF_00501 1.19e-154 merR2 - - K - - - helix_turn_helix, mercury resistance
IHONEDMF_00502 8.13e-82 - - - - - - - -
IHONEDMF_00504 3.7e-125 - - - L - - - DNA integration
IHONEDMF_00505 3.58e-161 - - - S - - - GyrI-like small molecule binding domain
IHONEDMF_00506 3.3e-45 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
IHONEDMF_00507 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IHONEDMF_00508 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
IHONEDMF_00509 3.05e-69 - - - - - - - -
IHONEDMF_00510 0.0 - - - K - - - WYL domain
IHONEDMF_00511 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IHONEDMF_00513 1.39e-112 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
IHONEDMF_00514 1.62e-180 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IHONEDMF_00515 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHONEDMF_00516 4.73e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IHONEDMF_00517 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
IHONEDMF_00518 5.57e-120 - - - T - - - Domain of unknown function (DUF4234)
IHONEDMF_00519 1.94e-130 - - - K - - - Bacterial regulatory proteins, tetR family
IHONEDMF_00520 3.56e-24 - - - - - - - -
IHONEDMF_00521 1.02e-64 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
IHONEDMF_00522 9.61e-54 - - - K - - - Helix-turn-helix
IHONEDMF_00523 8.45e-286 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
IHONEDMF_00524 6.79e-85 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
IHONEDMF_00525 6.55e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
IHONEDMF_00526 1.77e-120 - - - K - - - Transcriptional regulator PadR-like family
IHONEDMF_00527 2.69e-172 - - - L ko:K07457 - ko00000 endonuclease III
IHONEDMF_00528 8.04e-168 - - - S - - - Enoyl-(Acyl carrier protein) reductase
IHONEDMF_00529 4.85e-312 - - - V - - - MatE
IHONEDMF_00530 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHONEDMF_00531 1.36e-19 - - - KLT - - - Protein tyrosine kinase
IHONEDMF_00533 3.51e-219 - - - - - - - -
IHONEDMF_00534 1.88e-249 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
IHONEDMF_00535 2.41e-23 - - - K - - - MerR family regulatory protein
IHONEDMF_00536 5.01e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHONEDMF_00537 1.18e-228 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHONEDMF_00538 3.07e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IHONEDMF_00539 2.31e-230 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
IHONEDMF_00540 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHONEDMF_00541 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IHONEDMF_00542 7.76e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IHONEDMF_00543 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IHONEDMF_00545 3.2e-206 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
IHONEDMF_00546 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHONEDMF_00550 1.67e-169 - - - M - - - NLP P60 protein
IHONEDMF_00551 3.67e-88 - - - S - - - SPP1 phage holin
IHONEDMF_00552 2.44e-90 - - - - - - - -
IHONEDMF_00553 2.74e-66 - - - MU - - - outer membrane autotransporter barrel domain protein
IHONEDMF_00554 1.13e-302 - - - - - - - -
IHONEDMF_00555 1.72e-84 - - - - - - - -
IHONEDMF_00556 0.0 - - - S - - - Prophage endopeptidase tail
IHONEDMF_00557 9.1e-190 - - - S - - - phage tail
IHONEDMF_00558 0.0 - - - S - - - Phage-related minor tail protein
IHONEDMF_00559 1.77e-70 - - - - - - - -
IHONEDMF_00560 4.54e-108 - - - - - - - -
IHONEDMF_00561 7.13e-123 - - - - - - - -
IHONEDMF_00562 1.65e-93 - - - - - - - -
IHONEDMF_00563 2.21e-94 - - - - - - - -
IHONEDMF_00564 3.65e-103 - - - - - - - -
IHONEDMF_00565 8.56e-119 - - - - - - - -
IHONEDMF_00566 3.74e-85 - - - - - - - -
IHONEDMF_00567 7.08e-225 - - - S - - - Phage capsid family
IHONEDMF_00568 1.44e-102 - - - - - - - -
IHONEDMF_00570 2.73e-58 - - - - - - - -
IHONEDMF_00571 1.41e-307 - - - - - - - -
IHONEDMF_00572 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
IHONEDMF_00573 0.0 - - - S - - - Terminase
IHONEDMF_00574 1.89e-91 - - - - - - - -
IHONEDMF_00575 6.53e-149 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
IHONEDMF_00576 1.14e-86 - - - - ko:K07451 - ko00000,ko01000,ko02048 -
IHONEDMF_00579 5.69e-44 - - - K - - - Transcriptional regulator
IHONEDMF_00581 4.2e-96 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
IHONEDMF_00582 1.27e-46 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
IHONEDMF_00583 6.15e-183 - - - - - - - -
IHONEDMF_00585 2.92e-66 - - - - - - - -
IHONEDMF_00587 5.6e-142 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
IHONEDMF_00588 5.31e-107 - - - V - - - HNH endonuclease
IHONEDMF_00589 1.58e-37 - - - - - - - -
IHONEDMF_00590 1.85e-205 - - - K - - - Transcriptional regulator
IHONEDMF_00591 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
IHONEDMF_00592 1.19e-119 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
IHONEDMF_00594 8.23e-49 - - - - - - - -
IHONEDMF_00596 6.36e-50 - - - - - - - -
IHONEDMF_00598 2.18e-211 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
IHONEDMF_00599 1.34e-85 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
IHONEDMF_00600 2.02e-26 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
IHONEDMF_00601 2.41e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
IHONEDMF_00604 9.54e-153 - - - S - - - CYTH
IHONEDMF_00605 7.23e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
IHONEDMF_00606 8.35e-232 - - - - - - - -
IHONEDMF_00607 2.08e-242 - - - - - - - -
IHONEDMF_00608 9.94e-220 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
IHONEDMF_00609 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHONEDMF_00610 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHONEDMF_00611 3.24e-186 - - - - - - - -
IHONEDMF_00612 9.78e-169 - - - K - - - Bacterial regulatory proteins, tetR family
IHONEDMF_00613 7.08e-70 - - - G - - - Transmembrane secretion effector
IHONEDMF_00614 1.26e-199 - - - G - - - Transmembrane secretion effector
IHONEDMF_00615 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHONEDMF_00616 8.72e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
IHONEDMF_00617 1.37e-248 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IHONEDMF_00619 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00620 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHONEDMF_00621 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHONEDMF_00622 6.48e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
IHONEDMF_00623 9.69e-317 - - - S - - - Calcineurin-like phosphoesterase
IHONEDMF_00626 3.37e-88 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
IHONEDMF_00627 5.02e-134 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
IHONEDMF_00628 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHONEDMF_00630 2.96e-160 - - - S - - - HAD hydrolase, family IA, variant 3
IHONEDMF_00631 5.05e-258 - - - P - - - NMT1/THI5 like
IHONEDMF_00632 4.1e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
IHONEDMF_00633 9.25e-198 - - - - - - - -
IHONEDMF_00634 9.49e-163 - - - G - - - Phosphoglycerate mutase family
IHONEDMF_00635 0.0 - - - EGP - - - Major Facilitator Superfamily
IHONEDMF_00636 6.15e-127 - - - S - - - GtrA-like protein
IHONEDMF_00637 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
IHONEDMF_00638 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
IHONEDMF_00639 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
IHONEDMF_00640 4.65e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
IHONEDMF_00641 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
IHONEDMF_00642 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
IHONEDMF_00643 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00644 7.47e-123 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IHONEDMF_00645 2.2e-244 - - - C - - - Aldo/keto reductase family
IHONEDMF_00647 1.36e-132 - - - M - - - Belongs to the glycosyl hydrolase 30 family
IHONEDMF_00648 4.45e-21 - - - - - - - -
IHONEDMF_00650 0.0 intA - - L - - - Phage integrase, N-terminal SAM-like domain
IHONEDMF_00653 6.29e-135 - - - - - - - -
IHONEDMF_00654 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
IHONEDMF_00655 4.68e-78 - - - S - - - Bacterial mobilisation protein (MobC)
IHONEDMF_00656 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
IHONEDMF_00657 2.4e-230 - - - V - - - Abi-like protein
IHONEDMF_00658 2.3e-293 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
IHONEDMF_00660 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
IHONEDMF_00661 0.0 - - - - - - - -
IHONEDMF_00662 2.72e-20 - - - - - - - -
IHONEDMF_00663 2.79e-118 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
IHONEDMF_00664 1.11e-148 - - - K - - - WHG domain
IHONEDMF_00665 6.01e-50 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
IHONEDMF_00666 5.46e-172 - - - L ko:K07483 - ko00000 Integrase core domain
IHONEDMF_00667 1.57e-54 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
IHONEDMF_00668 0.0 - - - EGP - - - Major Facilitator Superfamily
IHONEDMF_00669 4.12e-184 - - - - - - - -
IHONEDMF_00670 3.25e-307 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
IHONEDMF_00671 2.86e-72 - - - L ko:K07454 - ko00000 HNH endonuclease
IHONEDMF_00672 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
IHONEDMF_00673 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IHONEDMF_00674 3.79e-136 - - - L ko:K07485 - ko00000 Transposase
IHONEDMF_00675 8.66e-57 - - - O - - - Glutaredoxin
IHONEDMF_00676 3.37e-193 - - - S ko:K07058 - ko00000 Virulence factor BrkB
IHONEDMF_00677 8.29e-129 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
IHONEDMF_00678 9.3e-53 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IHONEDMF_00679 3.17e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHONEDMF_00680 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHONEDMF_00681 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IHONEDMF_00682 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_00683 2.46e-132 - - - K - - - Transcriptional regulator C-terminal region
IHONEDMF_00684 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
IHONEDMF_00685 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
IHONEDMF_00687 1.15e-234 - - - S - - - Protein of unknown function (DUF559)
IHONEDMF_00688 2.47e-142 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHONEDMF_00689 1.78e-240 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHONEDMF_00690 1.5e-197 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_00691 7.99e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
IHONEDMF_00692 3.38e-206 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_00693 4.04e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_00694 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
IHONEDMF_00695 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IHONEDMF_00696 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IHONEDMF_00697 2.14e-87 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
IHONEDMF_00698 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
IHONEDMF_00699 2.44e-159 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
IHONEDMF_00700 2.17e-243 - - - K - - - Periplasmic binding protein domain
IHONEDMF_00701 7.12e-25 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IHONEDMF_00702 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
IHONEDMF_00703 5.41e-30 - - - L - - - Helix-turn-helix domain
IHONEDMF_00704 7.33e-12 - - - S - - - Protein of unknown function (DUF2442)
IHONEDMF_00705 8.59e-23 - - - K - - - Helix-turn-helix domain
IHONEDMF_00706 5.98e-134 - - - L - - - Belongs to the 'phage' integrase family
IHONEDMF_00707 2.37e-69 - - - V - - - Type I restriction modification DNA specificity domain
IHONEDMF_00708 2.23e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
IHONEDMF_00709 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
IHONEDMF_00710 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHONEDMF_00711 2.38e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
IHONEDMF_00712 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
IHONEDMF_00713 3.06e-179 hflK - - O - - - prohibitin homologues
IHONEDMF_00714 1.49e-309 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
IHONEDMF_00715 6.1e-296 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
IHONEDMF_00716 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
IHONEDMF_00717 2.86e-287 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IHONEDMF_00718 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_00719 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
IHONEDMF_00720 2.11e-119 - - - K - - - acetyltransferase
IHONEDMF_00721 2.16e-103 - - - EGP - - - Major Facilitator Superfamily
IHONEDMF_00722 1.73e-248 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
IHONEDMF_00723 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
IHONEDMF_00724 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
IHONEDMF_00725 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IHONEDMF_00726 8.1e-189 - - - S - - - Short repeat of unknown function (DUF308)
IHONEDMF_00727 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
IHONEDMF_00728 4.08e-127 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
IHONEDMF_00729 5.42e-219 - - - - - - - -
IHONEDMF_00730 2e-41 - - - - - - - -
IHONEDMF_00731 2.48e-196 - - - S - - - Domain of unknown function (DUF4357)
IHONEDMF_00732 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
IHONEDMF_00733 1.12e-140 - - - - - - - -
IHONEDMF_00735 7.24e-52 - 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K03427 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
IHONEDMF_00736 8.68e-229 - - - L - - - Phage integrase family
IHONEDMF_00737 8.29e-106 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHONEDMF_00741 1.03e-141 - - - - - - - -
IHONEDMF_00742 1.83e-244 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
IHONEDMF_00743 1.4e-282 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
IHONEDMF_00744 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
IHONEDMF_00745 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHONEDMF_00747 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHONEDMF_00748 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
IHONEDMF_00749 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHONEDMF_00750 2.92e-312 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
IHONEDMF_00751 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHONEDMF_00752 3.88e-206 - - - K - - - Helix-turn-helix domain, rpiR family
IHONEDMF_00753 4.27e-293 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
IHONEDMF_00754 2.12e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
IHONEDMF_00756 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHONEDMF_00757 8.31e-228 yogA - - C - - - Zinc-binding dehydrogenase
IHONEDMF_00758 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHONEDMF_00759 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHONEDMF_00760 4.79e-95 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IHONEDMF_00761 3.79e-61 - - - - - - - -
IHONEDMF_00762 1.3e-197 - - - S - - - TIGRFAM TIGR03943 family protein
IHONEDMF_00763 2.5e-258 - - - S ko:K07089 - ko00000 Predicted permease
IHONEDMF_00764 5.23e-32 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
IHONEDMF_00765 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
IHONEDMF_00766 4.38e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IHONEDMF_00767 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHONEDMF_00768 2.64e-63 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
IHONEDMF_00769 3.14e-179 - - - S - - - cobalamin synthesis protein
IHONEDMF_00770 7.81e-208 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
IHONEDMF_00771 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
IHONEDMF_00772 0.0 - - - S - - - Putative esterase
IHONEDMF_00773 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
IHONEDMF_00774 5.13e-305 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IHONEDMF_00775 2.1e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IHONEDMF_00776 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHONEDMF_00777 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
IHONEDMF_00778 9.82e-45 - - - - - - - -
IHONEDMF_00779 4.02e-91 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHONEDMF_00780 4.51e-44 - - - K - - - DNA-binding transcription factor activity
IHONEDMF_00781 2.92e-193 nnrE - - L - - - Uracil DNA glycosylase superfamily
IHONEDMF_00782 5.79e-136 - - - S - - - Protein of unknown function (DUF4230)
IHONEDMF_00783 2.72e-141 - - - - - - - -
IHONEDMF_00784 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
IHONEDMF_00785 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IHONEDMF_00786 4.7e-299 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHONEDMF_00787 0.0 - - - M - - - Parallel beta-helix repeats
IHONEDMF_00788 2.1e-289 - - - M - - - Glycosyl transferase 4-like domain
IHONEDMF_00789 5.42e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
IHONEDMF_00791 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHONEDMF_00792 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHONEDMF_00793 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHONEDMF_00794 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHONEDMF_00795 0.0 - - - S - - - Esterase-like activity of phytase
IHONEDMF_00796 1.52e-252 - - - EGP - - - Transmembrane secretion effector
IHONEDMF_00798 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHONEDMF_00799 1.61e-147 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHONEDMF_00800 5.95e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
IHONEDMF_00801 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IHONEDMF_00802 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IHONEDMF_00803 0.0 - - - S - - - Protein of unknown function DUF262
IHONEDMF_00804 1.44e-150 - - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_00805 0.0 - - - T - - - Histidine kinase
IHONEDMF_00806 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
IHONEDMF_00807 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
IHONEDMF_00808 8.12e-221 - - - EG - - - EamA-like transporter family
IHONEDMF_00809 6.07e-94 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
IHONEDMF_00810 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IHONEDMF_00811 3.58e-162 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHONEDMF_00812 1.89e-176 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
IHONEDMF_00813 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
IHONEDMF_00814 2.19e-156 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHONEDMF_00815 9.36e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IHONEDMF_00816 2.53e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
IHONEDMF_00817 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
IHONEDMF_00818 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHONEDMF_00819 1.2e-113 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IHONEDMF_00821 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHONEDMF_00822 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHONEDMF_00824 3.22e-246 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHONEDMF_00825 4.56e-142 - - - - - - - -
IHONEDMF_00826 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
IHONEDMF_00827 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
IHONEDMF_00828 7.75e-258 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IHONEDMF_00829 2.41e-158 - - - - - - - -
IHONEDMF_00830 1.04e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHONEDMF_00831 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
IHONEDMF_00832 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
IHONEDMF_00833 1.68e-65 - - - S - - - Protein of unknown function (DUF2975)
IHONEDMF_00834 1.65e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IHONEDMF_00835 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
IHONEDMF_00836 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
IHONEDMF_00837 3.3e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
IHONEDMF_00838 1.16e-241 - - - S - - - Protein of unknown function (DUF3071)
IHONEDMF_00839 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
IHONEDMF_00840 1.42e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IHONEDMF_00841 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHONEDMF_00842 2.33e-39 - - - - - - - -
IHONEDMF_00844 3.6e-266 - - - E - - - Belongs to the peptidase S1B family
IHONEDMF_00845 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
IHONEDMF_00846 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
IHONEDMF_00847 3.42e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHONEDMF_00848 6.49e-211 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IHONEDMF_00849 7.91e-117 - - - P - - - ABC-type metal ion transport system permease component
IHONEDMF_00850 6.96e-286 - - - S - - - Peptidase dimerisation domain
IHONEDMF_00851 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IHONEDMF_00852 2.33e-53 - - - - - - - -
IHONEDMF_00853 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
IHONEDMF_00854 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHONEDMF_00855 1.94e-146 - - - S - - - Protein of unknown function (DUF3000)
IHONEDMF_00856 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
IHONEDMF_00857 9.36e-310 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHONEDMF_00858 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
IHONEDMF_00859 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHONEDMF_00860 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHONEDMF_00861 1.44e-310 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHONEDMF_00866 1.28e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
IHONEDMF_00867 2.77e-289 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IHONEDMF_00868 4.26e-222 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IHONEDMF_00869 3.52e-151 safC - - S - - - O-methyltransferase
IHONEDMF_00870 2.81e-232 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
IHONEDMF_00871 1.29e-92 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
IHONEDMF_00872 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
IHONEDMF_00873 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
IHONEDMF_00874 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
IHONEDMF_00875 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
IHONEDMF_00876 9.86e-202 - - - S - - - Putative ABC-transporter type IV
IHONEDMF_00877 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
IHONEDMF_00879 1.53e-215 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_00880 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
IHONEDMF_00881 0.0 - - - I - - - PAP2 superfamily
IHONEDMF_00882 1.33e-167 - - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_00883 0.0 - - - T - - - Histidine kinase
IHONEDMF_00884 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
IHONEDMF_00885 2.47e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHONEDMF_00886 1.71e-212 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
IHONEDMF_00887 6.33e-188 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
IHONEDMF_00888 4.46e-238 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
IHONEDMF_00889 1.1e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
IHONEDMF_00890 2.72e-261 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHONEDMF_00891 9.77e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_00892 7.35e-292 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IHONEDMF_00893 7.17e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHONEDMF_00894 3.83e-312 - - - K - - - Fic/DOC family
IHONEDMF_00895 6.71e-163 - - - E - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00896 5.59e-78 yccF - - S - - - Inner membrane component domain
IHONEDMF_00897 6.35e-201 - - - J - - - Methyltransferase domain
IHONEDMF_00898 6.01e-101 - - - S - - - Cupin 2, conserved barrel domain protein
IHONEDMF_00899 0.0 - - - KLT - - - Protein tyrosine kinase
IHONEDMF_00900 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
IHONEDMF_00902 1.1e-30 - - - - - - - -
IHONEDMF_00903 1.9e-264 - - - S - - - Short C-terminal domain
IHONEDMF_00904 1.1e-112 - - - S - - - Helix-turn-helix
IHONEDMF_00905 4.07e-85 - - - S - - - Zincin-like metallopeptidase
IHONEDMF_00906 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IHONEDMF_00907 6.57e-66 - - - - - - - -
IHONEDMF_00908 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHONEDMF_00909 3.7e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
IHONEDMF_00910 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
IHONEDMF_00912 0.0 - - - M - - - Glycosyltransferase like family 2
IHONEDMF_00913 3.18e-153 - - - E - - - haloacid dehalogenase-like hydrolase
IHONEDMF_00914 5.43e-188 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
IHONEDMF_00915 2.75e-239 - - - S - - - Conserved hypothetical protein 698
IHONEDMF_00916 2.87e-71 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
IHONEDMF_00917 1.72e-204 - - - G - - - Phosphoglycerate mutase family
IHONEDMF_00918 2.75e-304 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
IHONEDMF_00919 3.06e-108 - - - K - - - AraC-like ligand binding domain
IHONEDMF_00921 1.03e-70 - - - IQ - - - oxidoreductase activity
IHONEDMF_00922 9.25e-176 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
IHONEDMF_00923 8.29e-174 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_00924 3.88e-206 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHONEDMF_00925 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHONEDMF_00926 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
IHONEDMF_00927 1.23e-133 - - - - - - - -
IHONEDMF_00928 2.61e-260 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHONEDMF_00929 1.82e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IHONEDMF_00930 8.32e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IHONEDMF_00931 1.69e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
IHONEDMF_00932 1.69e-232 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHONEDMF_00933 3.7e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IHONEDMF_00934 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHONEDMF_00935 7.1e-131 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
IHONEDMF_00936 0.0 - - - K - - - Putative DNA-binding domain
IHONEDMF_00937 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
IHONEDMF_00938 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IHONEDMF_00939 9.62e-142 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IHONEDMF_00940 1.44e-184 - - - S - - - Putative ABC-transporter type IV
IHONEDMF_00941 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHONEDMF_00942 7.8e-285 - - - L - - - Tetratricopeptide repeat
IHONEDMF_00943 2.08e-240 - - - G - - - Haloacid dehalogenase-like hydrolase
IHONEDMF_00945 3.26e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
IHONEDMF_00946 1.63e-136 - - - - - - - -
IHONEDMF_00947 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
IHONEDMF_00948 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
IHONEDMF_00949 2.59e-234 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHONEDMF_00950 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IHONEDMF_00951 8.76e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
IHONEDMF_00952 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IHONEDMF_00953 1.56e-227 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_00954 1.77e-162 - - - S - - - ABC-2 family transporter protein
IHONEDMF_00955 2.66e-157 - - - S - - - ABC-2 family transporter protein
IHONEDMF_00956 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
IHONEDMF_00957 3.57e-300 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHONEDMF_00958 2.56e-120 - - - - - - - -
IHONEDMF_00959 1.7e-186 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHONEDMF_00960 6.24e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHONEDMF_00962 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHONEDMF_00963 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHONEDMF_00964 1.35e-176 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
IHONEDMF_00965 1.08e-101 - - - S - - - Bacterial PH domain
IHONEDMF_00966 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
IHONEDMF_00968 5.47e-161 - - - - - - - -
IHONEDMF_00969 6.92e-171 - - - C - - - Putative TM nitroreductase
IHONEDMF_00970 4.38e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
IHONEDMF_00971 9.59e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
IHONEDMF_00972 9.17e-69 - - - KT - - - RESPONSE REGULATOR receiver
IHONEDMF_00973 9.24e-246 - - - V - - - VanZ like family
IHONEDMF_00974 7e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IHONEDMF_00975 5.4e-124 - - - S - - - Putative ABC-transporter type IV
IHONEDMF_00976 2.81e-13 - - - CE ko:K03294 - ko00000 Amino acid permease
IHONEDMF_00977 1.6e-193 - - - - - - - -
IHONEDMF_00979 5.77e-129 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
IHONEDMF_00980 3.19e-38 - - - EGP ko:K03446,ko:K03466,ko:K03762,ko:K08217 - br01600,ko00000,ko00002,ko01504,ko02000,ko03036 Major facilitator Superfamily
IHONEDMF_00981 3.96e-226 - - - M - - - heme binding
IHONEDMF_00982 1.31e-103 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHONEDMF_00983 1.9e-164 - - - - - - - -
IHONEDMF_00984 8.42e-172 - - - S - - - SOS response associated peptidase (SRAP)
IHONEDMF_00985 2.57e-99 qseC 2.7.13.3 - T ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Histidine kinase
IHONEDMF_00986 4.18e-237 - - - S - - - Acetyltransferase (GNAT) domain
IHONEDMF_00988 9.65e-50 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
IHONEDMF_00989 1.08e-73 - - - K - - - Transcriptional regulator
IHONEDMF_00990 2.65e-114 - - - K - - - FR47-like protein
IHONEDMF_00991 1.54e-147 - - - J - - - Acetyltransferase (GNAT) domain
IHONEDMF_00992 3.22e-82 - - - K - - - Protein of unknown function, DUF488
IHONEDMF_00993 4.04e-205 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IHONEDMF_00994 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00995 4.77e-178 - - - S - - - Domain of unknown function (DUF4194)
IHONEDMF_00996 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_00997 0.0 - - - E - - - Serine carboxypeptidase
IHONEDMF_00998 1.72e-208 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
IHONEDMF_00999 1.72e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
IHONEDMF_01000 1.12e-215 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IHONEDMF_01001 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IHONEDMF_01002 1.08e-160 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
IHONEDMF_01003 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
IHONEDMF_01004 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IHONEDMF_01005 6.31e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
IHONEDMF_01006 5.71e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
IHONEDMF_01007 4.23e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
IHONEDMF_01008 2.66e-249 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHONEDMF_01010 2.77e-216 - - - M - - - Peptidase family M23
IHONEDMF_01011 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
IHONEDMF_01012 0.0 - - - G - - - ABC transporter substrate-binding protein
IHONEDMF_01013 1.11e-305 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
IHONEDMF_01014 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
IHONEDMF_01015 5.1e-118 - - - - - - - -
IHONEDMF_01016 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
IHONEDMF_01017 1.05e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHONEDMF_01018 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IHONEDMF_01019 1.37e-187 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHONEDMF_01020 3.84e-165 - - - S - - - alpha beta
IHONEDMF_01021 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IHONEDMF_01022 7.62e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHONEDMF_01023 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
IHONEDMF_01024 1.42e-287 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IHONEDMF_01025 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IHONEDMF_01026 4.17e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHONEDMF_01027 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHONEDMF_01028 1.96e-264 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IHONEDMF_01029 3.78e-24 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IHONEDMF_01030 5.59e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01031 4.73e-216 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
IHONEDMF_01032 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHONEDMF_01033 7.02e-94 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
IHONEDMF_01034 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
IHONEDMF_01035 1.26e-125 - - - - - - - -
IHONEDMF_01037 2.52e-68 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
IHONEDMF_01038 9.78e-152 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
IHONEDMF_01039 1.79e-137 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
IHONEDMF_01040 1.03e-131 - - - D - - - Septum formation initiator
IHONEDMF_01041 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHONEDMF_01042 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
IHONEDMF_01043 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
IHONEDMF_01044 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHONEDMF_01045 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHONEDMF_01046 1.06e-125 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
IHONEDMF_01047 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IHONEDMF_01048 3.43e-194 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IHONEDMF_01049 1.21e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
IHONEDMF_01050 1.43e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IHONEDMF_01053 5.66e-278 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
IHONEDMF_01054 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IHONEDMF_01055 1.96e-261 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IHONEDMF_01056 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
IHONEDMF_01057 1.7e-298 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
IHONEDMF_01058 1.88e-251 - - - - - - - -
IHONEDMF_01059 1.63e-192 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01060 1.07e-244 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
IHONEDMF_01061 0.0 argE - - E - - - Peptidase dimerisation domain
IHONEDMF_01062 2.07e-134 - - - S - - - Protein of unknown function (DUF3043)
IHONEDMF_01063 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHONEDMF_01064 5.21e-183 - - - S - - - Domain of unknown function (DUF4191)
IHONEDMF_01065 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IHONEDMF_01066 1.22e-25 - - - - - - - -
IHONEDMF_01068 5.76e-20 - - - - - - - -
IHONEDMF_01071 2.36e-202 - - - S - - - Protein conserved in bacteria
IHONEDMF_01072 2.75e-268 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IHONEDMF_01073 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHONEDMF_01074 0.0 - - - S - - - Tetratricopeptide repeat
IHONEDMF_01075 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IHONEDMF_01076 6.02e-87 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
IHONEDMF_01077 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01078 3.37e-270 - - - E - - - Aminotransferase class I and II
IHONEDMF_01079 5.64e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IHONEDMF_01081 2.4e-136 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHONEDMF_01082 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_01083 0.0 - - - EGP - - - Major Facilitator Superfamily
IHONEDMF_01085 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
IHONEDMF_01086 0.0 - - - L - - - DEAD DEAH box helicase
IHONEDMF_01087 2.49e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
IHONEDMF_01088 7.35e-250 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01089 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01090 4.85e-195 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IHONEDMF_01091 5.87e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
IHONEDMF_01092 5.55e-121 - - - S - - - Aminoacyl-tRNA editing domain
IHONEDMF_01093 7.55e-84 - - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_01094 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IHONEDMF_01095 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
IHONEDMF_01096 2.4e-212 - - - S - - - Domain of Unknown Function (DUF349)
IHONEDMF_01097 1.34e-40 - - - S - - - Domain of Unknown Function (DUF349)
IHONEDMF_01101 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
IHONEDMF_01102 2.42e-237 uspA - - T - - - Belongs to the universal stress protein A family
IHONEDMF_01103 4.27e-251 - - - S - - - Protein of unknown function (DUF3027)
IHONEDMF_01104 7.13e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IHONEDMF_01105 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
IHONEDMF_01106 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
IHONEDMF_01107 4e-231 - - - - - - - -
IHONEDMF_01108 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
IHONEDMF_01109 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHONEDMF_01110 1.49e-58 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IHONEDMF_01111 7.36e-106 - - - S - - - LytR cell envelope-related transcriptional attenuator
IHONEDMF_01112 5.79e-183 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHONEDMF_01113 1.43e-250 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
IHONEDMF_01114 7.12e-229 - - - S - - - Protein of unknown function DUF58
IHONEDMF_01115 1.78e-121 - - - - - - - -
IHONEDMF_01116 3.22e-246 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
IHONEDMF_01117 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
IHONEDMF_01118 9.23e-117 - - - - - - - -
IHONEDMF_01120 0.0 - - - S - - - PGAP1-like protein
IHONEDMF_01121 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
IHONEDMF_01122 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
IHONEDMF_01123 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
IHONEDMF_01124 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IHONEDMF_01125 1.05e-28 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IHONEDMF_01126 1.98e-203 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
IHONEDMF_01127 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
IHONEDMF_01128 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
IHONEDMF_01129 2.58e-176 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
IHONEDMF_01130 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHONEDMF_01131 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IHONEDMF_01132 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHONEDMF_01133 3.73e-283 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHONEDMF_01134 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IHONEDMF_01135 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
IHONEDMF_01136 1.13e-223 - - - S - - - Protein conserved in bacteria
IHONEDMF_01138 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHONEDMF_01139 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
IHONEDMF_01140 2.33e-142 - - - - - - - -
IHONEDMF_01141 1.9e-315 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHONEDMF_01142 5.36e-172 - - - S - - - Protein of unknown function (DUF3159)
IHONEDMF_01143 2.19e-195 - - - S - - - Protein of unknown function (DUF3710)
IHONEDMF_01144 2.87e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
IHONEDMF_01145 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IHONEDMF_01146 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
IHONEDMF_01147 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IHONEDMF_01148 1.07e-211 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
IHONEDMF_01149 3.38e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01150 1.73e-238 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
IHONEDMF_01151 2.67e-56 - - - - - - - -
IHONEDMF_01152 7.31e-246 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
IHONEDMF_01153 1.18e-252 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IHONEDMF_01154 1.64e-120 - - - - - - - -
IHONEDMF_01155 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
IHONEDMF_01156 4.53e-301 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
IHONEDMF_01157 3.33e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
IHONEDMF_01158 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IHONEDMF_01159 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IHONEDMF_01160 2.1e-191 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
IHONEDMF_01161 1.17e-126 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHONEDMF_01162 2.29e-191 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHONEDMF_01163 1.86e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
IHONEDMF_01164 5.87e-229 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
IHONEDMF_01165 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHONEDMF_01166 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
IHONEDMF_01167 3.07e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHONEDMF_01168 2.74e-90 - - - S - - - Spermine/spermidine synthase domain
IHONEDMF_01169 4.14e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
IHONEDMF_01170 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHONEDMF_01171 6.06e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHONEDMF_01173 1.13e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IHONEDMF_01174 6.49e-249 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IHONEDMF_01175 3.35e-84 - - - - - - - -
IHONEDMF_01176 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IHONEDMF_01177 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHONEDMF_01178 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
IHONEDMF_01179 2.28e-291 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
IHONEDMF_01180 4.4e-310 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
IHONEDMF_01181 1.2e-164 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IHONEDMF_01182 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IHONEDMF_01183 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
IHONEDMF_01185 7.52e-126 - - - F - - - NUDIX domain
IHONEDMF_01186 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
IHONEDMF_01187 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IHONEDMF_01188 2.16e-248 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01189 5.3e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01190 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
IHONEDMF_01191 6.82e-270 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
IHONEDMF_01192 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHONEDMF_01193 1.44e-276 - - - GK - - - ROK family
IHONEDMF_01194 1.39e-168 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
IHONEDMF_01195 4.19e-283 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IHONEDMF_01196 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IHONEDMF_01197 6.45e-302 - - - G - - - Major Facilitator Superfamily
IHONEDMF_01198 1.18e-108 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHONEDMF_01201 7.49e-235 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
IHONEDMF_01202 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IHONEDMF_01203 1.1e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHONEDMF_01204 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
IHONEDMF_01205 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHONEDMF_01206 1.24e-260 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHONEDMF_01207 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHONEDMF_01208 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHONEDMF_01209 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
IHONEDMF_01210 2.29e-96 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IHONEDMF_01211 3.42e-259 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHONEDMF_01212 2.09e-116 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IHONEDMF_01213 0.0 - - - L - - - DNA helicase
IHONEDMF_01214 3.23e-290 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IHONEDMF_01215 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHONEDMF_01216 3.69e-59 - - - M - - - Lysin motif
IHONEDMF_01217 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHONEDMF_01218 4.73e-214 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHONEDMF_01219 1.96e-226 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IHONEDMF_01220 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHONEDMF_01221 4.62e-224 - - - - - - - -
IHONEDMF_01222 5.07e-157 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
IHONEDMF_01223 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
IHONEDMF_01224 1.03e-242 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IHONEDMF_01225 2e-75 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator Superfamily
IHONEDMF_01226 0.0 - - - S - - - Domain of unknown function (DUF5067)
IHONEDMF_01227 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IHONEDMF_01228 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
IHONEDMF_01229 8.32e-168 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
IHONEDMF_01230 3.31e-157 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHONEDMF_01231 1.84e-151 - - - - - - - -
IHONEDMF_01232 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
IHONEDMF_01233 5.31e-285 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHONEDMF_01234 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHONEDMF_01235 2.68e-232 - - - S - - - Protein conserved in bacteria
IHONEDMF_01238 1.5e-100 - - - S - - - Domain of unknown function (DUF4186)
IHONEDMF_01239 2.11e-221 dkgV - - C - - - Aldo/keto reductase family
IHONEDMF_01240 5.5e-199 - - - S - - - Aldo/keto reductase family
IHONEDMF_01241 2.5e-258 - - - K - - - WYL domain
IHONEDMF_01243 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
IHONEDMF_01244 1.34e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
IHONEDMF_01245 1.07e-163 - - - S - - - zinc-ribbon domain
IHONEDMF_01246 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
IHONEDMF_01247 1.11e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IHONEDMF_01248 8.35e-19 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IHONEDMF_01249 1.12e-243 - - - S - - - Domain of unknown function (DUF1963)
IHONEDMF_01250 1.03e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHONEDMF_01251 1.96e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IHONEDMF_01252 0.0 - - - I - - - acetylesterase activity
IHONEDMF_01253 4.85e-299 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IHONEDMF_01254 4.35e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IHONEDMF_01255 2.35e-305 - - - NU - - - Tfp pilus assembly protein FimV
IHONEDMF_01257 1.35e-105 - - - - - - - -
IHONEDMF_01258 1.06e-185 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
IHONEDMF_01259 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHONEDMF_01260 2.15e-284 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
IHONEDMF_01261 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
IHONEDMF_01262 3.39e-298 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
IHONEDMF_01263 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHONEDMF_01264 3.72e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IHONEDMF_01265 1.25e-82 - - - - - - - -
IHONEDMF_01267 1.62e-226 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IHONEDMF_01268 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHONEDMF_01269 1.65e-191 - - - V - - - DivIVA protein
IHONEDMF_01270 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
IHONEDMF_01271 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IHONEDMF_01272 8.03e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHONEDMF_01273 4.69e-314 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHONEDMF_01274 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
IHONEDMF_01275 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
IHONEDMF_01276 1.68e-200 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IHONEDMF_01277 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IHONEDMF_01278 1.62e-110 - - - - - - - -
IHONEDMF_01279 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
IHONEDMF_01280 3.45e-209 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IHONEDMF_01281 1.52e-81 - - - S - - - Thiamine-binding protein
IHONEDMF_01282 3.24e-247 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_01283 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
IHONEDMF_01284 3.54e-194 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IHONEDMF_01285 0.0 - - - S - - - Zincin-like metallopeptidase
IHONEDMF_01286 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IHONEDMF_01287 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
IHONEDMF_01288 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
IHONEDMF_01289 2.09e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
IHONEDMF_01290 4.82e-147 - - - S - - - Vitamin K epoxide reductase
IHONEDMF_01291 1.04e-215 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IHONEDMF_01292 3.31e-197 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IHONEDMF_01293 9.2e-220 - - - S - - - Patatin-like phospholipase
IHONEDMF_01294 1.85e-99 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
IHONEDMF_01295 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
IHONEDMF_01296 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_01297 3.51e-115 - - - K - - - MarR family
IHONEDMF_01298 1.62e-66 - - - M - - - Parallel beta-helix repeats
IHONEDMF_01299 4.46e-192 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
IHONEDMF_01300 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
IHONEDMF_01301 8.27e-232 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
IHONEDMF_01302 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IHONEDMF_01303 1.85e-137 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHONEDMF_01304 1.39e-236 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHONEDMF_01305 1.23e-52 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHONEDMF_01306 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IHONEDMF_01307 1.54e-305 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
IHONEDMF_01308 5.51e-239 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHONEDMF_01309 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
IHONEDMF_01310 8.1e-87 - - - - - - - -
IHONEDMF_01311 2.71e-74 - - - - - - - -
IHONEDMF_01312 2.26e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01313 0.0 - - - V - - - Efflux ABC transporter, permease protein
IHONEDMF_01314 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
IHONEDMF_01315 1.41e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
IHONEDMF_01316 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
IHONEDMF_01317 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IHONEDMF_01318 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
IHONEDMF_01319 1.55e-274 - - - K - - - Psort location Cytoplasmic, score
IHONEDMF_01320 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHONEDMF_01321 2.13e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHONEDMF_01322 7.11e-295 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
IHONEDMF_01324 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IHONEDMF_01325 5.02e-161 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IHONEDMF_01326 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
IHONEDMF_01327 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IHONEDMF_01328 1.42e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IHONEDMF_01329 1.28e-254 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
IHONEDMF_01330 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
IHONEDMF_01331 5.34e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHONEDMF_01332 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHONEDMF_01333 5.79e-167 - - - - - - - -
IHONEDMF_01334 4.08e-243 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
IHONEDMF_01335 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IHONEDMF_01336 2.38e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IHONEDMF_01337 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHONEDMF_01338 2.34e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
IHONEDMF_01341 9.21e-52 - - - S - - - Parallel beta-helix repeats
IHONEDMF_01342 5.3e-97 - - - E - - - Domain of unknown function (DUF5011)
IHONEDMF_01344 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IHONEDMF_01345 3.2e-176 - - - M - - - Protein of unknown function (DUF3152)
IHONEDMF_01346 5.99e-237 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IHONEDMF_01347 7.41e-190 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHONEDMF_01348 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
IHONEDMF_01349 0.0 - - - M - - - domain protein
IHONEDMF_01350 0.0 - - - M - - - LPXTG cell wall anchor motif
IHONEDMF_01351 3.23e-271 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IHONEDMF_01352 1.58e-186 - - - S - - - Domain of unknown function (DUF4854)
IHONEDMF_01353 8.13e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
IHONEDMF_01355 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IHONEDMF_01356 1.04e-169 - - - M - - - Mechanosensitive ion channel
IHONEDMF_01357 1.76e-152 - - - K - - - Bacterial regulatory proteins, tetR family
IHONEDMF_01358 3.21e-305 - - - S - - - Psort location Cytoplasmic, score 8.87
IHONEDMF_01359 1.67e-295 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
IHONEDMF_01360 7.4e-109 - - - M - - - Belongs to the glycosyl hydrolase 28 family
IHONEDMF_01363 2.36e-56 - - - K - - - Transcriptional regulator
IHONEDMF_01364 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
IHONEDMF_01365 0.00013 - - - TV ko:K05792 - ko00000 HNH endonuclease
IHONEDMF_01366 3.17e-38 - - - - - - - -
IHONEDMF_01371 1.8e-161 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
IHONEDMF_01372 8.43e-301 - - - K - - - Helix-turn-helix XRE-family like proteins
IHONEDMF_01373 1.77e-72 - - - L - - - RelB antitoxin
IHONEDMF_01375 8.3e-171 - - - K - - - helix_turn_helix, mercury resistance
IHONEDMF_01376 6.07e-309 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
IHONEDMF_01378 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
IHONEDMF_01379 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
IHONEDMF_01380 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
IHONEDMF_01381 3.02e-279 steT - - E ko:K03294 - ko00000 amino acid
IHONEDMF_01384 0.0 - - - - - - - -
IHONEDMF_01385 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
IHONEDMF_01386 3.78e-156 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
IHONEDMF_01387 7.85e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
IHONEDMF_01388 9.18e-109 - - - O - - - Hsp20/alpha crystallin family
IHONEDMF_01389 4.27e-227 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IHONEDMF_01390 3.22e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHONEDMF_01391 4.16e-46 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IHONEDMF_01392 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IHONEDMF_01393 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
IHONEDMF_01394 4.74e-132 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
IHONEDMF_01395 9.1e-281 - - - S - - - Endonuclease/Exonuclease/phosphatase family
IHONEDMF_01396 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHONEDMF_01397 4.14e-212 - - - P - - - Cation efflux family
IHONEDMF_01398 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IHONEDMF_01399 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
IHONEDMF_01400 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
IHONEDMF_01401 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
IHONEDMF_01402 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHONEDMF_01403 3.01e-184 - - - - - - - -
IHONEDMF_01404 3.08e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
IHONEDMF_01405 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IHONEDMF_01406 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHONEDMF_01407 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
IHONEDMF_01408 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
IHONEDMF_01410 1.65e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHONEDMF_01411 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IHONEDMF_01412 9.76e-153 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHONEDMF_01413 3.96e-228 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
IHONEDMF_01416 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IHONEDMF_01417 2.09e-272 - - - - - - - -
IHONEDMF_01419 6.19e-263 - - - - - - - -
IHONEDMF_01421 3.05e-107 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
IHONEDMF_01422 1.13e-36 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
IHONEDMF_01423 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
IHONEDMF_01424 1.56e-39 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
IHONEDMF_01425 1.13e-29 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
IHONEDMF_01426 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01427 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IHONEDMF_01429 8.57e-222 - - - K - - - Putative sugar-binding domain
IHONEDMF_01430 1.7e-282 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IHONEDMF_01431 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IHONEDMF_01432 3.12e-220 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
IHONEDMF_01433 8.39e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
IHONEDMF_01434 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHONEDMF_01435 2.08e-201 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IHONEDMF_01436 1.9e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHONEDMF_01437 3.6e-266 - - - K - - - helix_turn _helix lactose operon repressor
IHONEDMF_01438 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
IHONEDMF_01439 2.37e-198 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IHONEDMF_01440 1.91e-142 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IHONEDMF_01443 3.09e-216 - - - G - - - Glycosyl hydrolases family 43
IHONEDMF_01444 6.4e-133 - - - G - - - Glycosyl hydrolases family 43
IHONEDMF_01445 7.96e-259 - - - K - - - helix_turn _helix lactose operon repressor
IHONEDMF_01446 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
IHONEDMF_01447 8.53e-158 - - - L - - - Protein of unknown function (DUF1524)
IHONEDMF_01448 1.97e-295 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IHONEDMF_01449 1.63e-314 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
IHONEDMF_01450 1.3e-215 - - - L - - - Transposase and inactivated derivatives IS30 family
IHONEDMF_01451 4.31e-129 - - - K - - - cell envelope-related transcriptional attenuator
IHONEDMF_01452 1.11e-305 - - - - - - - -
IHONEDMF_01453 2.49e-230 - - - S ko:K21688 - ko00000 G5
IHONEDMF_01454 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
IHONEDMF_01455 8.16e-154 - - - F - - - Domain of unknown function (DUF4916)
IHONEDMF_01456 1.46e-205 - - - I - - - Alpha/beta hydrolase family
IHONEDMF_01458 0.0 - - - S - - - L,D-transpeptidase catalytic domain
IHONEDMF_01459 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IHONEDMF_01460 1.82e-269 - - - S - - - Uncharacterized conserved protein (DUF2183)
IHONEDMF_01461 4.66e-33 - - - S - - - Uncharacterized conserved protein (DUF2183)
IHONEDMF_01462 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
IHONEDMF_01463 1.72e-243 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IHONEDMF_01464 8.97e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
IHONEDMF_01465 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
IHONEDMF_01466 0.0 pon1 - - M - - - Transglycosylase
IHONEDMF_01467 2.04e-275 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
IHONEDMF_01468 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IHONEDMF_01469 1.2e-179 - - - K - - - DeoR C terminal sensor domain
IHONEDMF_01470 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
IHONEDMF_01471 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
IHONEDMF_01472 1.32e-308 - - - EGP - - - Sugar (and other) transporter
IHONEDMF_01473 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
IHONEDMF_01474 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
IHONEDMF_01475 1.62e-93 - - - - - - - -
IHONEDMF_01477 9.1e-157 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHONEDMF_01478 1.63e-77 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
IHONEDMF_01479 6.01e-235 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
IHONEDMF_01480 3.75e-142 - - - - - - - -
IHONEDMF_01481 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHONEDMF_01482 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHONEDMF_01483 2.55e-122 - - - T - - - Forkhead associated domain
IHONEDMF_01484 1.47e-101 - - - B - - - Belongs to the OprB family
IHONEDMF_01485 5.53e-210 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
IHONEDMF_01486 0.0 - - - E - - - Transglutaminase-like superfamily
IHONEDMF_01487 4.93e-303 - - - S - - - Protein of unknown function DUF58
IHONEDMF_01488 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
IHONEDMF_01489 0.0 - - - S - - - Fibronectin type 3 domain
IHONEDMF_01490 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IHONEDMF_01491 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
IHONEDMF_01492 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
IHONEDMF_01493 1.38e-194 - - - K - - - -acetyltransferase
IHONEDMF_01494 0.0 - - - G - - - Major Facilitator Superfamily
IHONEDMF_01495 1.03e-55 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
IHONEDMF_01496 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
IHONEDMF_01497 3e-47 - - - L - - - Transposase
IHONEDMF_01498 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHONEDMF_01499 5.92e-58 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHONEDMF_01500 5.07e-131 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHONEDMF_01501 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHONEDMF_01502 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
IHONEDMF_01503 0.0 vpr - - O - - - Subtilase family
IHONEDMF_01504 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHONEDMF_01505 3.18e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHONEDMF_01506 0.0 - - - S - - - zinc finger
IHONEDMF_01507 1.09e-138 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IHONEDMF_01508 7.65e-293 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
IHONEDMF_01509 9.17e-201 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
IHONEDMF_01510 2.78e-170 tmp1 - - S - - - Domain of unknown function (DUF4391)
IHONEDMF_01511 1.24e-192 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
IHONEDMF_01512 0.0 - - - OP - - - Sulfurtransferase TusA
IHONEDMF_01513 3.88e-233 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
IHONEDMF_01514 0.000209 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IHONEDMF_01516 3.7e-259 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
IHONEDMF_01517 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHONEDMF_01518 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHONEDMF_01519 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
IHONEDMF_01520 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHONEDMF_01522 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
IHONEDMF_01523 3.9e-213 - - - - - - - -
IHONEDMF_01524 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
IHONEDMF_01526 2.41e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
IHONEDMF_01527 2.67e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
IHONEDMF_01528 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHONEDMF_01529 3.99e-186 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
IHONEDMF_01530 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
IHONEDMF_01531 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
IHONEDMF_01532 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
IHONEDMF_01533 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
IHONEDMF_01535 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHONEDMF_01536 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
IHONEDMF_01537 4.31e-197 - - - - - - - -
IHONEDMF_01538 9.04e-231 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IHONEDMF_01539 1.49e-316 - - - M - - - LPXTG-motif cell wall anchor domain protein
IHONEDMF_01540 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
IHONEDMF_01541 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
IHONEDMF_01542 1.82e-131 - - - L - - - Helix-turn-helix domain
IHONEDMF_01543 8.89e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IHONEDMF_01544 3.79e-221 - - - K - - - Psort location Cytoplasmic, score
IHONEDMF_01545 0.0 - - - KLT - - - Protein tyrosine kinase
IHONEDMF_01546 6.08e-200 - - - O - - - Thioredoxin
IHONEDMF_01548 3.53e-279 rpfB - - S ko:K21688 - ko00000 G5
IHONEDMF_01549 6.28e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHONEDMF_01550 5.38e-213 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHONEDMF_01551 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
IHONEDMF_01552 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
IHONEDMF_01553 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
IHONEDMF_01554 0.0 - - - M - - - Conserved repeat domain
IHONEDMF_01555 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
IHONEDMF_01556 9.66e-259 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHONEDMF_01557 2.69e-310 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IHONEDMF_01558 1.05e-229 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
IHONEDMF_01559 2.59e-162 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
IHONEDMF_01560 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
IHONEDMF_01561 2.11e-227 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
IHONEDMF_01562 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
IHONEDMF_01563 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHONEDMF_01564 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHONEDMF_01565 5.36e-306 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHONEDMF_01566 1.85e-123 - - - S - - - Protein of unknown function (DUF721)
IHONEDMF_01567 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHONEDMF_01568 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHONEDMF_01569 4.11e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
IHONEDMF_01572 1.3e-238 - - - G - - - Glycosyl hydrolases family 43
IHONEDMF_01573 9.32e-240 - - - K - - - Periplasmic binding protein domain
IHONEDMF_01574 2.17e-289 - - - I - - - Serine aminopeptidase, S33
IHONEDMF_01575 1.56e-11 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_01578 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IHONEDMF_01579 8e-163 gntR - - K - - - FCD
IHONEDMF_01580 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHONEDMF_01581 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
IHONEDMF_01584 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
IHONEDMF_01585 4.39e-245 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_01586 5.12e-101 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IHONEDMF_01587 1.22e-53 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IHONEDMF_01588 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IHONEDMF_01589 5.97e-175 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
IHONEDMF_01590 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IHONEDMF_01591 2.83e-240 - - - EG - - - EamA-like transporter family
IHONEDMF_01592 1.37e-305 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
IHONEDMF_01593 1.14e-122 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_01594 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IHONEDMF_01595 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
IHONEDMF_01596 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
IHONEDMF_01597 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
IHONEDMF_01598 9.66e-309 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
IHONEDMF_01599 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHONEDMF_01600 0.0 - - - S - - - Threonine/Serine exporter, ThrE
IHONEDMF_01601 1.72e-224 - - - S - - - Amidohydrolase family
IHONEDMF_01602 4.09e-249 - - - S - - - Protein conserved in bacteria
IHONEDMF_01603 6.93e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IHONEDMF_01604 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
IHONEDMF_01605 2.26e-143 - - - T - - - protein histidine kinase activity
IHONEDMF_01606 5.04e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHONEDMF_01607 1.44e-33 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
IHONEDMF_01608 0.0 - - - M - - - Glycosyl hydrolases family 25
IHONEDMF_01609 1.17e-201 - - - M - - - Glycosyl transferase family 2
IHONEDMF_01610 4.11e-90 - - - L ko:K07485 - ko00000 Transposase
IHONEDMF_01611 4.91e-264 - - - S - - - Acyltransferase family
IHONEDMF_01612 0.0 - - - - - - - -
IHONEDMF_01613 0.0 - - - M - - - Glycosyl transferase family 8
IHONEDMF_01614 8.3e-223 - - - M - - - Glycosyl transferase, family 2
IHONEDMF_01615 0.0 - - - M - - - Belongs to the glycosyl hydrolase 43 family
IHONEDMF_01616 1.7e-162 - - - L - - - IstB-like ATP binding protein
IHONEDMF_01617 0.0 - - - L - - - Transposase
IHONEDMF_01618 1.38e-195 - - - M - - - Putative cell wall binding repeat 2
IHONEDMF_01619 6.7e-158 - - - L - - - Protein of unknown function (DUF1524)
IHONEDMF_01620 0.0 - - - M - - - hydrolase, family 25
IHONEDMF_01621 7.98e-310 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IHONEDMF_01622 4.9e-179 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
IHONEDMF_01623 0.0 - - - M - - - Glycosyl transferase family 8
IHONEDMF_01624 2.46e-272 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
IHONEDMF_01625 1.1e-19 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
IHONEDMF_01626 4.14e-193 - - - K - - - Transposase IS116 IS110 IS902
IHONEDMF_01627 4.53e-150 tnp3521a2 - - L - - - Integrase core domain
IHONEDMF_01628 2.86e-58 - - - L ko:K07483 - ko00000 Transposase
IHONEDMF_01629 3.43e-13 - - - - - - - -
IHONEDMF_01631 1.79e-58 - - - L - - - Transposase DDE domain
IHONEDMF_01632 5.42e-191 bglA 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
IHONEDMF_01633 4.67e-248 - - - L - - - Transposase, Mutator family
IHONEDMF_01634 7.28e-288 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
IHONEDMF_01635 1.76e-41 - - - L - - - NUDIX domain
IHONEDMF_01636 4.47e-121 - - - - - - - -
IHONEDMF_01637 1.97e-257 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHONEDMF_01638 1.21e-272 - - - G - - - Transmembrane secretion effector
IHONEDMF_01639 3.34e-151 - - - K - - - Bacterial regulatory proteins, tetR family
IHONEDMF_01640 1.9e-17 - - - - - - - -
IHONEDMF_01641 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
IHONEDMF_01642 4.95e-57 - - - L - - - Integrase core domain
IHONEDMF_01643 1.6e-69 istB - - L - - - IstB-like ATP binding protein
IHONEDMF_01644 2.19e-60 - - - L ko:K07485 - ko00000 Transposase
IHONEDMF_01645 5.53e-96 - - - I - - - Sterol carrier protein
IHONEDMF_01646 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IHONEDMF_01647 7.68e-47 - - - - - - - -
IHONEDMF_01648 4.85e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
IHONEDMF_01649 1.47e-155 - - - L - - - HTH-like domain
IHONEDMF_01650 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
IHONEDMF_01651 3.28e-99 crgA - - D - - - Involved in cell division
IHONEDMF_01652 1.18e-182 - - - S - - - Bacterial protein of unknown function (DUF881)
IHONEDMF_01653 3.81e-294 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IHONEDMF_01654 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
IHONEDMF_01655 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IHONEDMF_01656 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IHONEDMF_01657 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IHONEDMF_01658 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IHONEDMF_01659 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
IHONEDMF_01660 1.44e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
IHONEDMF_01661 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
IHONEDMF_01662 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
IHONEDMF_01663 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
IHONEDMF_01664 5.86e-263 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
IHONEDMF_01665 5.97e-207 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
IHONEDMF_01666 1.76e-260 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
IHONEDMF_01667 9.28e-216 - - - EG - - - EamA-like transporter family
IHONEDMF_01668 1.35e-146 - - - - - - - -
IHONEDMF_01670 4.98e-252 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHONEDMF_01672 0.0 - - - KL - - - Domain of unknown function (DUF3427)
IHONEDMF_01673 3.19e-117 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
IHONEDMF_01674 9.18e-60 - - - D - - - DivIVA domain protein
IHONEDMF_01675 3.02e-70 - - - S - - - Putative heavy-metal-binding
IHONEDMF_01676 6.18e-199 - - - I - - - Serine aminopeptidase, S33
IHONEDMF_01677 2.72e-111 - - - Q - - - Acetyltransferase (GNAT) domain
IHONEDMF_01678 4.38e-43 - - - L ko:K07483 - ko00000 transposase activity
IHONEDMF_01679 9.61e-69 tnp3521a2 - - L - - - Integrase core domain
IHONEDMF_01680 4.61e-54 tnp3521a2 - - L - - - Integrase core domain
IHONEDMF_01684 9.1e-97 - - - L - - - HindVP restriction endonuclease
IHONEDMF_01685 1.62e-143 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IHONEDMF_01686 3.09e-44 - - - - - - - -
IHONEDMF_01687 2.12e-48 - - - M - - - LysM domain
IHONEDMF_01688 1.35e-71 - - - M - - - Glycosyl hydrolases family 25
IHONEDMF_01689 1.99e-20 - - - L - - - Transposase, Mutator family
IHONEDMF_01691 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IHONEDMF_01692 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
IHONEDMF_01693 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
IHONEDMF_01694 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
IHONEDMF_01695 1.18e-223 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IHONEDMF_01697 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
IHONEDMF_01698 1.23e-55 - - - S - - - Bacterial mobilisation protein (MobC)
IHONEDMF_01699 3.76e-163 - - - S - - - Domain of unknown function (DUF4417)
IHONEDMF_01701 4.37e-80 - - - - - - - -
IHONEDMF_01702 4.81e-84 - - - - - - - -
IHONEDMF_01703 7.82e-65 - - - E - - - IrrE N-terminal-like domain
IHONEDMF_01705 1.42e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
IHONEDMF_01706 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IHONEDMF_01707 1.25e-252 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
IHONEDMF_01708 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHONEDMF_01709 5.91e-209 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHONEDMF_01710 3.1e-80 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHONEDMF_01711 2.8e-256 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IHONEDMF_01712 1.38e-102 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
IHONEDMF_01713 0.0 scrT - - G - - - Transporter major facilitator family protein
IHONEDMF_01714 0.0 - - - EGP - - - Sugar (and other) transporter
IHONEDMF_01715 7.92e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
IHONEDMF_01716 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
IHONEDMF_01717 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IHONEDMF_01718 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
IHONEDMF_01719 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
IHONEDMF_01720 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IHONEDMF_01721 0.0 - - - S - - - Glycosyl transferase, family 2
IHONEDMF_01722 0.0 - - - - - - - -
IHONEDMF_01723 1.05e-85 - - - S - - - Zincin-like metallopeptidase
IHONEDMF_01724 2.72e-199 - - - T - - - Eukaryotic phosphomannomutase
IHONEDMF_01725 3.04e-167 pyrE_1 - - S - - - Phosphoribosyl transferase domain
IHONEDMF_01726 1.85e-92 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
IHONEDMF_01727 5.91e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
IHONEDMF_01728 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
IHONEDMF_01729 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IHONEDMF_01730 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
IHONEDMF_01731 2.56e-108 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IHONEDMF_01732 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
IHONEDMF_01733 1.15e-209 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01734 3.14e-232 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
IHONEDMF_01735 7e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHONEDMF_01736 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IHONEDMF_01737 4.53e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHONEDMF_01738 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHONEDMF_01739 1.15e-130 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
IHONEDMF_01740 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
IHONEDMF_01741 3.31e-140 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
IHONEDMF_01743 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
IHONEDMF_01744 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHONEDMF_01745 1.32e-221 - - - L - - - NIF3 (NGG1p interacting factor 3)
IHONEDMF_01746 5.63e-155 - - - L - - - NUDIX domain
IHONEDMF_01747 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
IHONEDMF_01748 6.61e-277 - - - - - - - -
IHONEDMF_01750 2.38e-20 - - - - - - - -
IHONEDMF_01751 1.3e-58 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IHONEDMF_01752 5.61e-23 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IHONEDMF_01753 4.21e-21 - - - U - - - Major Facilitator Superfamily
IHONEDMF_01754 3.5e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IHONEDMF_01755 1.6e-94 - - - K - - - helix_turn_helix, mercury resistance
IHONEDMF_01756 7.87e-209 - - - S - - - Aldo/keto reductase family
IHONEDMF_01757 9.75e-131 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IHONEDMF_01758 1.95e-164 - - - - - - - -
IHONEDMF_01760 9.85e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
IHONEDMF_01761 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHONEDMF_01762 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHONEDMF_01763 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
IHONEDMF_01764 7.56e-93 - - - S - - - Domain of unknown function (DUF1846)
IHONEDMF_01765 2.71e-101 - - - - - - - -
IHONEDMF_01767 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IHONEDMF_01768 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IHONEDMF_01769 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
IHONEDMF_01770 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
IHONEDMF_01771 1.54e-153 - - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_01772 9.81e-297 - - - T - - - Histidine kinase
IHONEDMF_01773 2.51e-56 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
IHONEDMF_01774 5.01e-228 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01775 7.94e-290 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IHONEDMF_01776 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IHONEDMF_01777 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
IHONEDMF_01778 3.71e-262 - - - L - - - Transposase and inactivated derivatives IS30 family
IHONEDMF_01780 8.14e-117 - - - - - - - -
IHONEDMF_01781 7.23e-85 - - - D - - - MobA/MobL family
IHONEDMF_01782 9e-64 - - - L ko:K07483 - ko00000 Transposase
IHONEDMF_01783 2.92e-232 tnp3521a2 - - L - - - Integrase core domain
IHONEDMF_01784 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
IHONEDMF_01785 9.3e-53 - - - - - - - -
IHONEDMF_01786 1.71e-144 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
IHONEDMF_01788 2.27e-56 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHONEDMF_01790 1.13e-305 pbuX - - F ko:K03458 - ko00000 Permease family
IHONEDMF_01791 1.54e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHONEDMF_01792 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
IHONEDMF_01793 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IHONEDMF_01794 2.46e-84 - - - S - - - Domain of unknown function (DUF4418)
IHONEDMF_01795 2.18e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IHONEDMF_01796 2.83e-174 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IHONEDMF_01797 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHONEDMF_01798 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
IHONEDMF_01799 7.56e-174 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
IHONEDMF_01800 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
IHONEDMF_01801 7.33e-50 - - - - - - - -
IHONEDMF_01802 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHONEDMF_01803 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHONEDMF_01804 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHONEDMF_01805 4.35e-68 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
IHONEDMF_01806 1.57e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHONEDMF_01807 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHONEDMF_01808 2.27e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
IHONEDMF_01809 4.78e-138 - - - - - - - -
IHONEDMF_01810 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
IHONEDMF_01811 1.31e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
IHONEDMF_01812 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHONEDMF_01813 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
IHONEDMF_01814 2.5e-299 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
IHONEDMF_01815 6.12e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
IHONEDMF_01816 3.62e-306 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHONEDMF_01817 1.19e-131 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
IHONEDMF_01818 2.56e-141 - - - S - - - Iron-sulfur cluster assembly protein
IHONEDMF_01819 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHONEDMF_01820 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
IHONEDMF_01822 2.03e-108 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHONEDMF_01823 2.09e-44 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHONEDMF_01824 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
IHONEDMF_01825 1.49e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
IHONEDMF_01826 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHONEDMF_01827 0.0 corC - - S - - - CBS domain
IHONEDMF_01828 1.96e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHONEDMF_01829 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
IHONEDMF_01830 6.9e-259 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
IHONEDMF_01831 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
IHONEDMF_01832 2.44e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IHONEDMF_01833 8.5e-242 - - - S ko:K06889 - ko00000 alpha beta
IHONEDMF_01834 1.17e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IHONEDMF_01835 1.58e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
IHONEDMF_01836 2.34e-61 - - - S - - - phosphoesterase or phosphohydrolase
IHONEDMF_01837 9.66e-126 - - - T - - - RNA ligase
IHONEDMF_01838 1.61e-175 - - - S - - - UPF0126 domain
IHONEDMF_01839 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IHONEDMF_01840 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHONEDMF_01841 1.63e-312 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IHONEDMF_01842 1.49e-16 - - - S ko:K07149 - ko00000 Membrane
IHONEDMF_01843 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
IHONEDMF_01844 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
IHONEDMF_01845 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
IHONEDMF_01846 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IHONEDMF_01847 5.23e-107 - - - - - - - -
IHONEDMF_01848 1.67e-312 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
IHONEDMF_01849 1.99e-232 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IHONEDMF_01850 4.59e-202 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
IHONEDMF_01851 6.05e-146 - - - S ko:K07126 - ko00000 Sel1-like repeats.
IHONEDMF_01852 1.3e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IHONEDMF_01853 1.37e-78 - - - S - - - Short C-terminal domain
IHONEDMF_01854 1.11e-226 - - - L ko:K07485 - ko00000 Transposase
IHONEDMF_01855 1.35e-38 - - - - ko:K07485 - ko00000 -
IHONEDMF_01856 3.82e-39 - - - - - - - -
IHONEDMF_01857 8.33e-30 - - - - - - - -
IHONEDMF_01858 0.0 - - - KL - - - Type III restriction enzyme res subunit
IHONEDMF_01859 3.18e-49 - - - L - - - Eco57I restriction-modification methylase
IHONEDMF_01860 1.65e-70 - - - L - - - Eco57I restriction-modification methylase
IHONEDMF_01861 6.12e-233 - - - V - - - Type III restriction enzyme res subunit
IHONEDMF_01862 1.99e-68 - - - S - - - SIR2-like domain
IHONEDMF_01863 9.57e-110 - - - S ko:K06915 - ko00000 AAA-like domain
IHONEDMF_01864 5.07e-160 - - - S ko:K06915 - ko00000 AAA-like domain
IHONEDMF_01865 0.0 - - - S - - - Protein of unknown function DUF262
IHONEDMF_01866 3.25e-40 - - - - - - - -
IHONEDMF_01867 1.94e-98 - - - E - - - Rard protein
IHONEDMF_01868 1.18e-30 rarD - - S ko:K05786 - ko00000,ko02000 EamA-like transporter family
IHONEDMF_01869 5.65e-228 - - - I - - - alpha/beta hydrolase fold
IHONEDMF_01870 4.92e-266 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IHONEDMF_01871 4.11e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
IHONEDMF_01872 4.22e-310 - - - L - - - Phage integrase, N-terminal SAM-like domain
IHONEDMF_01873 7.54e-58 - - - E - - - IrrE N-terminal-like domain
IHONEDMF_01874 6.55e-22 - - - - - - - -
IHONEDMF_01875 8.97e-65 - - - - - - - -
IHONEDMF_01876 7.91e-132 - - - S - - - Virulence protein RhuM family
IHONEDMF_01877 2.07e-72 - - - - - - - -
IHONEDMF_01878 3.33e-47 - - - - - - - -
IHONEDMF_01879 2.65e-69 - - - - - - - -
IHONEDMF_01880 2.72e-20 - - - - - - - -
IHONEDMF_01881 1.12e-156 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)