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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MLEOMEED_00003	2.34e-92	-	-	-	-	-	-	-	-
MLEOMEED_00004	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MLEOMEED_00005	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00006	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MLEOMEED_00008	5.23e-205	yybS	-	-	S	-	-	-	membrane
MLEOMEED_00009	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MLEOMEED_00010	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MLEOMEED_00011	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLEOMEED_00012	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MLEOMEED_00013	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
MLEOMEED_00015	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MLEOMEED_00016	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MLEOMEED_00017	1.19e-101	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_00018	6.38e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLEOMEED_00023	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_00024	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_00025	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00026	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00027	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLEOMEED_00028	2.42e-281	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLEOMEED_00029	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLEOMEED_00030	1.5e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLEOMEED_00031	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MLEOMEED_00032	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MLEOMEED_00034	3.03e-239	-	-	-	S	-	-	-	aspartate phosphatase
MLEOMEED_00035	3.84e-113	yycN	-	-	K	-	-	-	Acetyltransferase
MLEOMEED_00036	1.68e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLEOMEED_00037	1.77e-281	yycP	-	-	-	-	-	-	-
MLEOMEED_00038	1.7e-45	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MLEOMEED_00040	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLEOMEED_00041	1.25e-93	-	-	-	-	-	-	-	-
MLEOMEED_00043	1.23e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLEOMEED_00044	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MLEOMEED_00045	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MLEOMEED_00047	0.0	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MLEOMEED_00048	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MLEOMEED_00049	1.04e-104	yngA	-	-	S	-	-	-	membrane
MLEOMEED_00050	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MLEOMEED_00051	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
MLEOMEED_00052	4.46e-297	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
MLEOMEED_00053	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLEOMEED_00054	1.48e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MLEOMEED_00055	7.02e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MLEOMEED_00056	1.23e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MLEOMEED_00057	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MLEOMEED_00058	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLEOMEED_00059	1.31e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MLEOMEED_00060	4.3e-41	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
MLEOMEED_00061	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MLEOMEED_00062	2.12e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MLEOMEED_00063	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MLEOMEED_00064	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_00065	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_00066	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_00067	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_00068	3.18e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MLEOMEED_00069	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MLEOMEED_00070	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLEOMEED_00071	7.39e-103	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLEOMEED_00072	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLEOMEED_00073	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLEOMEED_00074	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLEOMEED_00075	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLEOMEED_00076	7.06e-22	-	-	-	-	-	-	-	-
MLEOMEED_00077	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MLEOMEED_00078	1.47e-216	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MLEOMEED_00079	1.57e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MLEOMEED_00080	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_00081	9.13e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MLEOMEED_00082	1.14e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MLEOMEED_00083	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MLEOMEED_00084	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MLEOMEED_00085	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00086	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MLEOMEED_00087	1.96e-245	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MLEOMEED_00089	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MLEOMEED_00090	4.3e-92	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MLEOMEED_00091	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_00092	2.09e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLEOMEED_00093	6.7e-56	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MLEOMEED_00094	1.2e-201	yugF	-	-	I	-	-	-	Hydrolase
MLEOMEED_00095	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00096	6.62e-256	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MLEOMEED_00097	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MLEOMEED_00098	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MLEOMEED_00099	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLEOMEED_00100	5.56e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MLEOMEED_00101	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MLEOMEED_00103	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
MLEOMEED_00104	1.76e-233	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MLEOMEED_00105	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MLEOMEED_00106	1.35e-51	-	-	-	-	-	-	-	-
MLEOMEED_00107	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MLEOMEED_00108	1.07e-301	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MLEOMEED_00109	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MLEOMEED_00110	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MLEOMEED_00111	5e-48	-	-	-	-	-	-	-	-
MLEOMEED_00112	1.06e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MLEOMEED_00113	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_00114	6.34e-300	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_00115	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_00116	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_00117	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MLEOMEED_00118	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MLEOMEED_00119	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MLEOMEED_00120	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MLEOMEED_00121	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MLEOMEED_00122	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MLEOMEED_00123	3.8e-256	yubA	-	-	S	-	-	-	transporter activity
MLEOMEED_00124	6.02e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLEOMEED_00126	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
MLEOMEED_00127	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MLEOMEED_00128	1.08e-195	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLEOMEED_00129	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
MLEOMEED_00130	1.85e-301	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
MLEOMEED_00131	1.83e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MLEOMEED_00132	5.83e-118	yuaB	-	-	-	-	-	-	-
MLEOMEED_00133	3.53e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MLEOMEED_00134	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MLEOMEED_00135	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MLEOMEED_00136	8.58e-139	yuaD	-	-	-	-	-	-	-
MLEOMEED_00137	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
MLEOMEED_00138	4.06e-110	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MLEOMEED_00139	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MLEOMEED_00140	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
MLEOMEED_00141	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MLEOMEED_00142	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
MLEOMEED_00144	7.24e-304	-	-	-	J	-	-	-	4Fe-4S single cluster domain
MLEOMEED_00145	0.0	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
MLEOMEED_00146	8.07e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MLEOMEED_00147	3.99e-313	skfF	-	-	S	-	-	-	ABC transporter
MLEOMEED_00148	3.88e-118	-	-	-	C	-	-	-	HEAT repeats
MLEOMEED_00149	5.88e-103	-	-	-	CO	-	-	-	Thioredoxin-like domain
MLEOMEED_00150	8.07e-233	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLEOMEED_00151	2.93e-159	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MLEOMEED_00152	4.12e-221	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
MLEOMEED_00154	2.49e-181	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MLEOMEED_00155	6.61e-196	ybdN	-	-	-	-	-	-	-
MLEOMEED_00156	1.19e-278	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MLEOMEED_00157	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MLEOMEED_00158	2.76e-65	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MLEOMEED_00159	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLEOMEED_00160	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MLEOMEED_00161	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLEOMEED_00162	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLEOMEED_00163	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MLEOMEED_00164	1.82e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLEOMEED_00165	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLEOMEED_00166	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLEOMEED_00167	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MLEOMEED_00168	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MLEOMEED_00169	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLEOMEED_00170	4.29e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLEOMEED_00171	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MLEOMEED_00172	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MLEOMEED_00173	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLEOMEED_00174	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MLEOMEED_00175	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLEOMEED_00176	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLEOMEED_00177	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLEOMEED_00178	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLEOMEED_00179	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MLEOMEED_00180	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLEOMEED_00181	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLEOMEED_00182	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MLEOMEED_00183	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLEOMEED_00184	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLEOMEED_00185	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLEOMEED_00186	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLEOMEED_00187	8.78e-238	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MLEOMEED_00188	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MLEOMEED_00189	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLEOMEED_00190	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MLEOMEED_00191	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLEOMEED_00192	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLEOMEED_00193	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLEOMEED_00194	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLEOMEED_00195	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLEOMEED_00196	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLEOMEED_00197	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MLEOMEED_00198	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLEOMEED_00199	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLEOMEED_00200	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLEOMEED_00201	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLEOMEED_00202	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLEOMEED_00203	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLEOMEED_00204	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLEOMEED_00205	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLEOMEED_00206	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLEOMEED_00207	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MLEOMEED_00208	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MLEOMEED_00209	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLEOMEED_00210	6.17e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLEOMEED_00211	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MLEOMEED_00212	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLEOMEED_00213	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MLEOMEED_00214	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLEOMEED_00215	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLEOMEED_00216	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLEOMEED_00217	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MLEOMEED_00218	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLEOMEED_00219	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLEOMEED_00220	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLEOMEED_00221	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLEOMEED_00222	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLEOMEED_00223	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MLEOMEED_00224	2.14e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MLEOMEED_00225	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MLEOMEED_00226	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MLEOMEED_00227	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLEOMEED_00228	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
MLEOMEED_00229	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MLEOMEED_00230	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MLEOMEED_00231	1.06e-75	ynfC	-	-	-	-	-	-	-
MLEOMEED_00232	1.82e-18	-	-	-	-	-	-	-	-
MLEOMEED_00233	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLEOMEED_00234	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLEOMEED_00235	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MLEOMEED_00236	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLEOMEED_00237	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MLEOMEED_00238	1.63e-71	yneQ	-	-	-	-	-	-	-
MLEOMEED_00239	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MLEOMEED_00240	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MLEOMEED_00242	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
MLEOMEED_00243	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLEOMEED_00244	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLEOMEED_00245	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MLEOMEED_00246	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MLEOMEED_00247	1.21e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MLEOMEED_00248	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MLEOMEED_00249	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MLEOMEED_00250	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MLEOMEED_00251	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MLEOMEED_00252	9.02e-256	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLEOMEED_00253	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLEOMEED_00254	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MLEOMEED_00255	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MLEOMEED_00256	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MLEOMEED_00257	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MLEOMEED_00258	3.66e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLEOMEED_00259	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MLEOMEED_00260	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MLEOMEED_00261	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MLEOMEED_00262	5.41e-134	yjaV	-	-	-	-	-	-	-
MLEOMEED_00263	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MLEOMEED_00264	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MLEOMEED_00265	2.67e-38	yjzB	-	-	-	-	-	-	-
MLEOMEED_00266	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLEOMEED_00267	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLEOMEED_00268	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MLEOMEED_00269	3.81e-139	yrkC	-	-	G	-	-	-	Cupin domain
MLEOMEED_00270	2.15e-195	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MLEOMEED_00271	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_00272	1.95e-197	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MLEOMEED_00274	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLEOMEED_00275	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
MLEOMEED_00276	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MLEOMEED_00277	4.83e-108	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MLEOMEED_00278	5.52e-133	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MLEOMEED_00279	3.66e-115	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MLEOMEED_00281	3.83e-132	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MLEOMEED_00282	1.16e-209	-	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00283	7.78e-176	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLEOMEED_00284	1.36e-71	-	-	-	S	-	-	-	MORN repeat variant
MLEOMEED_00285	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MLEOMEED_00286	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MLEOMEED_00288	2.52e-197	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MLEOMEED_00289	9.82e-315	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLEOMEED_00290	3.16e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MLEOMEED_00291	4.51e-156	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MLEOMEED_00292	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MLEOMEED_00293	3.6e-25	-	-	-	-	-	-	-	-
MLEOMEED_00294	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MLEOMEED_00295	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLEOMEED_00296	4.53e-203	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MLEOMEED_00297	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MLEOMEED_00298	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MLEOMEED_00299	5.26e-88	ywpG	-	-	-	-	-	-	-
MLEOMEED_00300	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
MLEOMEED_00301	4.63e-68	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MLEOMEED_00302	8.54e-198	ywpD	-	-	T	-	-	-	Histidine kinase
MLEOMEED_00303	1.13e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLEOMEED_00304	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLEOMEED_00305	5.45e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MLEOMEED_00306	4.1e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MLEOMEED_00307	6.18e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MLEOMEED_00308	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MLEOMEED_00309	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MLEOMEED_00310	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
MLEOMEED_00311	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_00312	1.02e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
MLEOMEED_00313	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MLEOMEED_00314	8e-309	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MLEOMEED_00315	2.56e-134	yjgF	-	-	Q	-	-	-	Isochorismatase family
MLEOMEED_00316	4.15e-100	-	-	-	-	-	-	-	-
MLEOMEED_00317	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MLEOMEED_00318	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MLEOMEED_00319	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MLEOMEED_00320	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
MLEOMEED_00321	2.13e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MLEOMEED_00322	1.55e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MLEOMEED_00323	3.28e-22	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MLEOMEED_00324	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MLEOMEED_00325	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLEOMEED_00326	3.41e-184	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MLEOMEED_00327	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MLEOMEED_00328	1.29e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MLEOMEED_00329	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00330	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLEOMEED_00331	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MLEOMEED_00332	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MLEOMEED_00333	1.11e-202	yoaV	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_00334	6.84e-103	yoaW	-	-	-	-	-	-	-
MLEOMEED_00335	3.88e-153	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
MLEOMEED_00336	9.26e-218	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MLEOMEED_00340	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MLEOMEED_00341	1.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MLEOMEED_00342	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MLEOMEED_00343	7.88e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLEOMEED_00344	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
MLEOMEED_00345	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLEOMEED_00346	2.78e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLEOMEED_00347	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLEOMEED_00348	2.27e-216	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MLEOMEED_00349	1.03e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MLEOMEED_00350	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLEOMEED_00351	3.77e-218	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MLEOMEED_00352	6.68e-196	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MLEOMEED_00353	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLEOMEED_00354	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLEOMEED_00355	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLEOMEED_00356	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MLEOMEED_00357	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLEOMEED_00358	1.25e-238	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MLEOMEED_00359	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MLEOMEED_00360	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MLEOMEED_00363	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MLEOMEED_00364	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MLEOMEED_00365	2.21e-139	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MLEOMEED_00366	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MLEOMEED_00367	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLEOMEED_00368	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLEOMEED_00369	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_00370	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MLEOMEED_00371	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLEOMEED_00372	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MLEOMEED_00373	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLEOMEED_00374	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLEOMEED_00375	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLEOMEED_00376	9e-310	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLEOMEED_00377	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLEOMEED_00378	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MLEOMEED_00379	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MLEOMEED_00380	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLEOMEED_00381	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MLEOMEED_00382	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00383	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MLEOMEED_00384	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLEOMEED_00385	1.05e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLEOMEED_00386	1.91e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
MLEOMEED_00387	5.05e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MLEOMEED_00388	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLEOMEED_00389	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MLEOMEED_00390	7.26e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLEOMEED_00391	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MLEOMEED_00392	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MLEOMEED_00393	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MLEOMEED_00394	1.1e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MLEOMEED_00395	2.42e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MLEOMEED_00396	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MLEOMEED_00397	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00398	2.82e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLEOMEED_00399	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MLEOMEED_00400	5.05e-260	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MLEOMEED_00401	3.28e-133	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLEOMEED_00402	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MLEOMEED_00403	3.82e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MLEOMEED_00404	4.37e-206	ykgA	-	-	E	-	-	-	Amidinotransferase
MLEOMEED_00405	9.83e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MLEOMEED_00406	1.77e-238	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00407	2.56e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLEOMEED_00408	1.24e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MLEOMEED_00409	4.26e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MLEOMEED_00411	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MLEOMEED_00412	6.22e-242	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00413	6.35e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00414	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00415	2.42e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MLEOMEED_00416	1.54e-183	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
MLEOMEED_00417	6.72e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLEOMEED_00419	1.34e-230	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MLEOMEED_00420	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLEOMEED_00422	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MLEOMEED_00423	1.55e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MLEOMEED_00424	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MLEOMEED_00425	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MLEOMEED_00426	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MLEOMEED_00427	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLEOMEED_00428	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MLEOMEED_00429	3.28e-151	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00430	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
MLEOMEED_00431	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MLEOMEED_00432	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MLEOMEED_00434	1.15e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLEOMEED_00435	2.96e-151	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
MLEOMEED_00436	6.88e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_00437	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MLEOMEED_00438	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLEOMEED_00439	1.54e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLEOMEED_00440	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MLEOMEED_00441	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MLEOMEED_00442	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00443	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MLEOMEED_00444	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MLEOMEED_00445	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLEOMEED_00446	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLEOMEED_00447	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MLEOMEED_00448	4.63e-255	yutH	-	-	S	-	-	-	Spore coat protein
MLEOMEED_00449	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MLEOMEED_00450	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLEOMEED_00451	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MLEOMEED_00452	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00453	9.45e-145	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLEOMEED_00454	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLEOMEED_00455	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MLEOMEED_00456	4.25e-172	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MLEOMEED_00457	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MLEOMEED_00458	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MLEOMEED_00459	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MLEOMEED_00460	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MLEOMEED_00461	2.72e-82	yunG	-	-	-	-	-	-	-
MLEOMEED_00462	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLEOMEED_00463	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MLEOMEED_00464	1.46e-300	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
MLEOMEED_00465	1.58e-283	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MLEOMEED_00466	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MLEOMEED_00467	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MLEOMEED_00468	2.42e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLEOMEED_00469	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLEOMEED_00470	4.85e-194	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLEOMEED_00471	2.62e-144	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MLEOMEED_00472	5.12e-243	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLEOMEED_00474	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLEOMEED_00475	4.9e-303	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLEOMEED_00476	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
MLEOMEED_00477	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00478	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MLEOMEED_00479	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MLEOMEED_00480	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MLEOMEED_00481	1.24e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_00482	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MLEOMEED_00483	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLEOMEED_00484	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MLEOMEED_00485	1.42e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MLEOMEED_00487	3.35e-56	-	-	-	-	-	-	-	-
MLEOMEED_00488	2.14e-87	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_00489	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MLEOMEED_00490	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MLEOMEED_00491	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLEOMEED_00492	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MLEOMEED_00493	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLEOMEED_00494	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLEOMEED_00495	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MLEOMEED_00496	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MLEOMEED_00497	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLEOMEED_00498	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MLEOMEED_00499	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
MLEOMEED_00500	1.32e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MLEOMEED_00501	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MLEOMEED_00502	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLEOMEED_00503	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MLEOMEED_00504	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MLEOMEED_00505	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MLEOMEED_00506	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MLEOMEED_00507	2.86e-14	-	-	-	S	-	-	-	YuzL-like protein
MLEOMEED_00508	2.09e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MLEOMEED_00509	2.23e-54	-	-	-	-	-	-	-	-
MLEOMEED_00510	2.12e-70	yusN	-	-	M	-	-	-	Coat F domain
MLEOMEED_00511	3.83e-99	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MLEOMEED_00512	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MLEOMEED_00513	1.76e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MLEOMEED_00514	6.81e-82	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_00515	4.48e-67	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_00516	1.52e-206	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MLEOMEED_00517	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MLEOMEED_00518	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MLEOMEED_00519	2.01e-87	-	-	-	S	-	-	-	YusW-like protein
MLEOMEED_00520	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MLEOMEED_00521	1.21e-41	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MLEOMEED_00522	6.65e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_00523	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MLEOMEED_00524	9.63e-306	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLEOMEED_00525	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_00526	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_00527	2.65e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLEOMEED_00528	5.85e-13	-	-	-	-	-	-	-	-
MLEOMEED_00529	4.81e-168	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MLEOMEED_00530	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MLEOMEED_00531	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLEOMEED_00532	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MLEOMEED_00533	2.86e-68	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MLEOMEED_00534	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLEOMEED_00535	3.16e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLEOMEED_00536	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLEOMEED_00537	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MLEOMEED_00538	1.21e-98	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MLEOMEED_00539	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MLEOMEED_00541	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MLEOMEED_00542	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLEOMEED_00543	3.66e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MLEOMEED_00544	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLEOMEED_00545	3.8e-175	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MLEOMEED_00546	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_00547	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MLEOMEED_00548	7.28e-144	ykoF	-	-	S	-	-	-	YKOF-related Family
MLEOMEED_00549	1.28e-160	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_00550	8.05e-312	ykoH	-	-	T	-	-	-	Histidine kinase
MLEOMEED_00551	3.35e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MLEOMEED_00552	2.24e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MLEOMEED_00553	1.45e-08	-	-	-	-	-	-	-	-
MLEOMEED_00555	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MLEOMEED_00556	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
MLEOMEED_00557	1.63e-25	-	-	-	-	-	-	-	-
MLEOMEED_00558	3.04e-36	ykoL	-	-	-	-	-	-	-
MLEOMEED_00559	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MLEOMEED_00560	1.19e-281	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MLEOMEED_00561	2.48e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MLEOMEED_00562	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MLEOMEED_00563	0.0	ykoS	-	-	-	-	-	-	-
MLEOMEED_00564	5.72e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MLEOMEED_00565	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MLEOMEED_00566	7.55e-206	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLEOMEED_00567	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MLEOMEED_00568	4.48e-153	ykoX	-	-	S	-	-	-	membrane-associated protein
MLEOMEED_00569	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLEOMEED_00570	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_00571	9.33e-219	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MLEOMEED_00572	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MLEOMEED_00573	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MLEOMEED_00574	3.4e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MLEOMEED_00575	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MLEOMEED_00577	8.33e-31	ykzE	-	-	-	-	-	-	-
MLEOMEED_00578	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLEOMEED_00579	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_00580	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLEOMEED_00582	1.62e-253	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLEOMEED_00583	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLEOMEED_00584	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLEOMEED_00585	4.81e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MLEOMEED_00586	3.39e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLEOMEED_00587	1.07e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLEOMEED_00588	4.52e-147	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLEOMEED_00589	1.5e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLEOMEED_00590	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MLEOMEED_00592	5.84e-95	eag	-	-	-	-	-	-	-
MLEOMEED_00593	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MLEOMEED_00594	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MLEOMEED_00595	1.09e-94	yxxG	-	-	-	-	-	-	-
MLEOMEED_00596	3.69e-111	-	-	-	-	-	-	-	-
MLEOMEED_00597	1.12e-82	-	-	-	-	-	-	-	-
MLEOMEED_00598	8.76e-99	yxiG	-	-	-	-	-	-	-
MLEOMEED_00599	1.2e-57	-	-	-	-	-	-	-	-
MLEOMEED_00600	6.22e-107	-	-	-	-	-	-	-	-
MLEOMEED_00601	3.79e-125	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
MLEOMEED_00602	5.53e-65	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MLEOMEED_00605	3.28e-279	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MLEOMEED_00606	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLEOMEED_00607	3.97e-294	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MLEOMEED_00608	2.75e-145	-	-	-	-	-	-	-	-
MLEOMEED_00609	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MLEOMEED_00610	2.62e-185	bglS	-	-	M	-	-	-	licheninase activity
MLEOMEED_00611	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MLEOMEED_00612	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MLEOMEED_00613	9.65e-65	yxiS	-	-	-	-	-	-	-
MLEOMEED_00614	2.96e-29	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MLEOMEED_00615	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLEOMEED_00616	4.55e-206	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MLEOMEED_00617	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MLEOMEED_00618	4.65e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLEOMEED_00619	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLEOMEED_00620	5.83e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLEOMEED_00621	9.77e-279	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MLEOMEED_00622	7.74e-280	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MLEOMEED_00623	2.57e-114	yxjI	-	-	S	-	-	-	LURP-one-related
MLEOMEED_00626	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MLEOMEED_00627	5.66e-150	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
MLEOMEED_00628	7.13e-261	-	-	-	T	-	-	-	Signal transduction histidine kinase
MLEOMEED_00629	5.63e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
MLEOMEED_00630	1.53e-213	-	-	-	K	-	-	-	LysR substrate binding domain
MLEOMEED_00631	2.01e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MLEOMEED_00632	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MLEOMEED_00633	1.66e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MLEOMEED_00634	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLEOMEED_00635	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLEOMEED_00636	1.16e-211	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MLEOMEED_00637	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00638	1.58e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MLEOMEED_00640	0.0	-	-	-	O	-	-	-	Peptidase family M48
MLEOMEED_00641	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MLEOMEED_00642	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MLEOMEED_00643	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MLEOMEED_00644	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MLEOMEED_00645	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MLEOMEED_00646	2.01e-206	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLEOMEED_00647	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MLEOMEED_00648	9.06e-125	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_00649	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
MLEOMEED_00650	1.75e-43	-	-	-	-	-	-	-	-
MLEOMEED_00651	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MLEOMEED_00652	2.09e-213	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_00653	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLEOMEED_00654	3.02e-275	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MLEOMEED_00655	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MLEOMEED_00656	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MLEOMEED_00657	8.94e-28	yxzF	-	-	-	-	-	-	-
MLEOMEED_00658	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MLEOMEED_00659	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MLEOMEED_00660	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLEOMEED_00661	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_00662	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLEOMEED_00663	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MLEOMEED_00664	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_00665	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLEOMEED_00666	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_00667	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MLEOMEED_00668	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_00669	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MLEOMEED_00670	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MLEOMEED_00671	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MLEOMEED_00672	2.7e-298	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLEOMEED_00673	2.15e-115	ywaE	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00674	3.96e-164	ywaF	-	-	S	-	-	-	Integral membrane protein
MLEOMEED_00675	6.53e-217	gspA	-	-	M	-	-	-	General stress
MLEOMEED_00676	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MLEOMEED_00677	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_00678	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MLEOMEED_00679	9.36e-317	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLEOMEED_00680	7.78e-165	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MLEOMEED_00681	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MLEOMEED_00682	1.3e-283	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MLEOMEED_00683	1.32e-39	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MLEOMEED_00684	1.29e-280	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
MLEOMEED_00685	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MLEOMEED_00686	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLEOMEED_00687	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00688	3.25e-185	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLEOMEED_00689	7.69e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLEOMEED_00690	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MLEOMEED_00691	6.21e-249	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MLEOMEED_00692	3.23e-310	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MLEOMEED_00693	1.08e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MLEOMEED_00694	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLEOMEED_00695	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MLEOMEED_00697	4.16e-159	ywcC	-	-	K	-	-	-	transcriptional regulator
MLEOMEED_00698	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MLEOMEED_00699	5.56e-291	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLEOMEED_00700	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00701	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00702	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MLEOMEED_00703	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00704	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00705	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MLEOMEED_00706	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MLEOMEED_00707	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MLEOMEED_00708	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00709	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLEOMEED_00710	1.37e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00711	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MLEOMEED_00712	3.98e-248	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
MLEOMEED_00713	2.65e-133	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_00714	3.51e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLEOMEED_00715	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MLEOMEED_00716	6.89e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLEOMEED_00717	1.31e-283	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MLEOMEED_00718	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MLEOMEED_00719	2.68e-28	-	-	-	-	-	-	-	-
MLEOMEED_00721	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MLEOMEED_00722	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MLEOMEED_00723	3.42e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLEOMEED_00724	5.15e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00725	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MLEOMEED_00726	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MLEOMEED_00727	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLEOMEED_00728	9.4e-206	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MLEOMEED_00729	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLEOMEED_00730	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLEOMEED_00731	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLEOMEED_00732	4.01e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MLEOMEED_00733	1.14e-277	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MLEOMEED_00734	4.41e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MLEOMEED_00735	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLEOMEED_00736	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLEOMEED_00737	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MLEOMEED_00738	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MLEOMEED_00739	2.32e-107	yjbX	-	-	S	-	-	-	Spore coat protein
MLEOMEED_00740	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MLEOMEED_00741	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MLEOMEED_00742	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MLEOMEED_00743	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
MLEOMEED_00744	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MLEOMEED_00745	3.03e-76	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MLEOMEED_00748	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MLEOMEED_00749	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MLEOMEED_00750	6.31e-51	-	-	-	-	-	-	-	-
MLEOMEED_00751	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_00752	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MLEOMEED_00753	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MLEOMEED_00754	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MLEOMEED_00755	6.4e-281	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MLEOMEED_00756	2.13e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MLEOMEED_00757	2.58e-274	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
MLEOMEED_00760	3.75e-269	-	-	-	S	-	-	-	Putative amidase domain
MLEOMEED_00761	1.52e-68	yjcN	-	-	-	-	-	-	-
MLEOMEED_00764	2.24e-106	-	-	-	L	-	-	-	Transposase
MLEOMEED_00765	5.68e-100	yjcP	-	-	-	-	-	-	-
MLEOMEED_00766	1.01e-65	-	-	-	S	-	-	-	YjcQ protein
MLEOMEED_00767	3.29e-121	yqaS	-	-	L	-	-	-	DNA packaging
MLEOMEED_00768	3.8e-63	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MLEOMEED_00769	3.42e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_00770	0.000759	-	-	-	-	-	-	-	-
MLEOMEED_00771	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MLEOMEED_00772	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_00773	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MLEOMEED_00774	4.79e-78	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MLEOMEED_00775	1.36e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MLEOMEED_00777	1.01e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLEOMEED_00778	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MLEOMEED_00779	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MLEOMEED_00780	5.31e-224	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLEOMEED_00782	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MLEOMEED_00783	2.22e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
MLEOMEED_00784	5.6e-30	yjfB	-	-	S	-	-	-	Putative motility protein
MLEOMEED_00785	3.24e-219	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MLEOMEED_00786	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MLEOMEED_00787	1.22e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MLEOMEED_00788	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MLEOMEED_00789	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MLEOMEED_00791	1.91e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MLEOMEED_00793	1.48e-289	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MLEOMEED_00794	8.74e-280	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLEOMEED_00795	1.11e-41	-	-	-	-	-	-	-	-
MLEOMEED_00796	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MLEOMEED_00797	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MLEOMEED_00798	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MLEOMEED_00799	1.09e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MLEOMEED_00800	8.91e-121	yjlB	-	-	S	-	-	-	Cupin domain
MLEOMEED_00801	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MLEOMEED_00802	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MLEOMEED_00803	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MLEOMEED_00804	6.34e-316	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MLEOMEED_00805	2.02e-248	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MLEOMEED_00806	1.6e-246	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MLEOMEED_00807	1.66e-274	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MLEOMEED_00808	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_00809	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
MLEOMEED_00810	6.95e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MLEOMEED_00811	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MLEOMEED_00812	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MLEOMEED_00813	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MLEOMEED_00814	4.87e-106	yjoA	-	-	S	-	-	-	DinB family
MLEOMEED_00815	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MLEOMEED_00816	1.6e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MLEOMEED_00818	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
MLEOMEED_00819	1.37e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MLEOMEED_00820	3.31e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
MLEOMEED_00821	1.47e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
MLEOMEED_00822	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MLEOMEED_00823	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MLEOMEED_00824	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MLEOMEED_00826	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MLEOMEED_00827	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MLEOMEED_00831	5.95e-112	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLEOMEED_00832	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MLEOMEED_00833	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MLEOMEED_00834	0.0	yqbA	-	-	S	-	-	-	portal protein
MLEOMEED_00835	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MLEOMEED_00836	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
MLEOMEED_00837	2.06e-85	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MLEOMEED_00838	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MLEOMEED_00839	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MLEOMEED_00840	2.87e-101	xkdJ	-	-	-	-	-	-	-
MLEOMEED_00841	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MLEOMEED_00842	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MLEOMEED_00843	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MLEOMEED_00844	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MLEOMEED_00845	1.77e-158	xkdP	-	-	S	-	-	-	Lysin motif
MLEOMEED_00846	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
MLEOMEED_00847	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MLEOMEED_00848	1.97e-92	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MLEOMEED_00849	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLEOMEED_00850	9.63e-136	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MLEOMEED_00851	4.43e-56	-	-	-	-	-	-	-	-
MLEOMEED_00852	0.0	-	-	-	-	-	-	-	-
MLEOMEED_00853	8.68e-74	xkdW	-	-	S	-	-	-	XkdW protein
MLEOMEED_00854	9.34e-33	xkdX	-	-	-	-	-	-	-
MLEOMEED_00855	1.51e-198	xepA	-	-	-	-	-	-	-
MLEOMEED_00856	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MLEOMEED_00857	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
MLEOMEED_00858	5.76e-212	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MLEOMEED_00859	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MLEOMEED_00860	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MLEOMEED_00861	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MLEOMEED_00862	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLEOMEED_00863	7.7e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MLEOMEED_00865	2.36e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_00866	8.93e-220	ybfA	-	-	K	-	-	-	FR47-like protein
MLEOMEED_00867	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MLEOMEED_00868	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MLEOMEED_00869	7.3e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MLEOMEED_00870	0.0	ybeC	-	-	E	-	-	-	amino acid
MLEOMEED_00871	1.11e-54	ybyB	-	-	-	-	-	-	-
MLEOMEED_00872	9.97e-317	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MLEOMEED_00873	3.86e-195	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MLEOMEED_00874	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
MLEOMEED_00875	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MLEOMEED_00876	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_00877	0.0	-	-	-	J	-	-	-	LlaJI restriction endonuclease
MLEOMEED_00878	3.67e-254	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
MLEOMEED_00880	1.43e-297	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MLEOMEED_00881	0.0	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
MLEOMEED_00882	6.93e-88	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
MLEOMEED_00884	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLEOMEED_00885	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLEOMEED_00886	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MLEOMEED_00887	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MLEOMEED_00888	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLEOMEED_00889	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLEOMEED_00890	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLEOMEED_00891	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLEOMEED_00892	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MLEOMEED_00893	1.63e-241	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLEOMEED_00894	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLEOMEED_00895	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MLEOMEED_00896	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MLEOMEED_00897	3.06e-237	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLEOMEED_00900	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
MLEOMEED_00901	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MLEOMEED_00902	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_00903	2.85e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_00904	2.88e-221	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLEOMEED_00905	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MLEOMEED_00906	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MLEOMEED_00907	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MLEOMEED_00908	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MLEOMEED_00909	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MLEOMEED_00910	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MLEOMEED_00911	1.45e-232	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MLEOMEED_00913	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MLEOMEED_00914	7.21e-194	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MLEOMEED_00915	1.43e-277	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLEOMEED_00916	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MLEOMEED_00917	2.51e-159	yflK	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_00918	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MLEOMEED_00919	6.9e-27	yflI	-	-	-	-	-	-	-
MLEOMEED_00920	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MLEOMEED_00921	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MLEOMEED_00922	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLEOMEED_00923	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MLEOMEED_00924	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MLEOMEED_00925	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MLEOMEED_00926	2.19e-249	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
MLEOMEED_00928	2.28e-271	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
MLEOMEED_00929	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MLEOMEED_00930	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_00931	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MLEOMEED_00932	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MLEOMEED_00933	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
MLEOMEED_00934	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MLEOMEED_00935	8.44e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MLEOMEED_00936	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_00937	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MLEOMEED_00938	2.14e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLEOMEED_00939	2.53e-67	yfkI	-	-	S	-	-	-	gas vesicle protein
MLEOMEED_00940	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MLEOMEED_00941	1.64e-12	-	-	-	-	-	-	-	-
MLEOMEED_00942	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_00943	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MLEOMEED_00944	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
MLEOMEED_00945	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MLEOMEED_00946	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
MLEOMEED_00947	3.26e-36	yfjT	-	-	-	-	-	-	-
MLEOMEED_00948	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MLEOMEED_00949	4.82e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLEOMEED_00950	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MLEOMEED_00951	1.94e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLEOMEED_00952	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLEOMEED_00953	3e-53	-	-	-	S	-	-	-	YfzA-like protein
MLEOMEED_00954	1.21e-243	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLEOMEED_00955	9.55e-111	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MLEOMEED_00957	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLEOMEED_00958	2.75e-244	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLEOMEED_00959	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLEOMEED_00960	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLEOMEED_00961	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MLEOMEED_00962	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MLEOMEED_00963	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
MLEOMEED_00964	1.53e-104	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
MLEOMEED_00965	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
MLEOMEED_00966	2.5e-185	yfjC	-	-	-	-	-	-	-
MLEOMEED_00967	1.94e-270	yfjB	-	-	-	-	-	-	-
MLEOMEED_00968	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
MLEOMEED_00969	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLEOMEED_00970	7.45e-182	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MLEOMEED_00971	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_00972	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MLEOMEED_00973	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MLEOMEED_00974	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
MLEOMEED_00975	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MLEOMEED_00976	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
MLEOMEED_00977	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_00978	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
MLEOMEED_00979	5.17e-295	-	-	-	S	-	-	-	Oxidoreductase
MLEOMEED_00981	7.54e-276	baeS	-	-	T	-	-	-	Histidine kinase
MLEOMEED_00982	1.05e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MLEOMEED_00983	3.35e-218	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_00984	3.66e-274	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MLEOMEED_00985	4.56e-267	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MLEOMEED_00986	1.89e-128	padR	-	-	K	-	-	-	transcriptional
MLEOMEED_00987	1.14e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MLEOMEED_00988	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MLEOMEED_00989	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MLEOMEED_00990	5.59e-64	-	-	-	-	-	-	-	-
MLEOMEED_00991	2.51e-125	ybcF	-	-	P	-	-	-	carbonic anhydrase
MLEOMEED_00992	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
MLEOMEED_00993	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLEOMEED_00994	4.49e-130	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLEOMEED_00995	2.25e-157	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MLEOMEED_00996	3.67e-227	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLEOMEED_00997	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MLEOMEED_00998	2.94e-141	pksA	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_00999	1.38e-127	ymcC	-	-	S	-	-	-	Membrane
MLEOMEED_01001	7.19e-93	-	-	-	S	-	-	-	Regulatory protein YrvL
MLEOMEED_01002	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLEOMEED_01003	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLEOMEED_01004	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MLEOMEED_01005	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MLEOMEED_01006	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLEOMEED_01007	4.15e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLEOMEED_01008	3.02e-255	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLEOMEED_01009	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MLEOMEED_01010	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MLEOMEED_01011	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MLEOMEED_01012	8.43e-282	pbpX	-	-	V	-	-	-	Beta-lactamase
MLEOMEED_01013	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLEOMEED_01014	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MLEOMEED_01015	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLEOMEED_01016	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MLEOMEED_01017	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MLEOMEED_01018	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MLEOMEED_01019	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLEOMEED_01020	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
MLEOMEED_01021	3.45e-301	albE	-	-	S	-	-	-	Peptidase M16
MLEOMEED_01022	2.08e-267	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_01023	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_01024	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MLEOMEED_01025	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
MLEOMEED_01026	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MLEOMEED_01027	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLEOMEED_01028	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLEOMEED_01029	1.2e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MLEOMEED_01030	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLEOMEED_01031	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLEOMEED_01032	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MLEOMEED_01033	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MLEOMEED_01034	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MLEOMEED_01035	1.29e-235	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MLEOMEED_01036	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLEOMEED_01037	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLEOMEED_01038	1.63e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MLEOMEED_01039	5.18e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLEOMEED_01040	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLEOMEED_01041	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MLEOMEED_01042	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLEOMEED_01043	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MLEOMEED_01044	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MLEOMEED_01045	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MLEOMEED_01046	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MLEOMEED_01047	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLEOMEED_01048	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLEOMEED_01049	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MLEOMEED_01050	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLEOMEED_01051	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MLEOMEED_01052	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLEOMEED_01053	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLEOMEED_01054	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MLEOMEED_01055	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLEOMEED_01056	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MLEOMEED_01057	6.91e-101	ylxL	-	-	-	-	-	-	-
MLEOMEED_01058	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_01059	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLEOMEED_01060	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLEOMEED_01061	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MLEOMEED_01062	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MLEOMEED_01063	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLEOMEED_01064	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MLEOMEED_01065	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MLEOMEED_01066	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLEOMEED_01067	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLEOMEED_01068	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MLEOMEED_01069	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MLEOMEED_01070	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MLEOMEED_01071	5.54e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MLEOMEED_01072	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MLEOMEED_01073	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLEOMEED_01074	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLEOMEED_01075	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MLEOMEED_01076	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MLEOMEED_01077	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MLEOMEED_01078	2.31e-314	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MLEOMEED_01079	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MLEOMEED_01080	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MLEOMEED_01081	2.11e-308	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLEOMEED_01082	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MLEOMEED_01083	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLEOMEED_01084	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MLEOMEED_01085	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MLEOMEED_01086	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MLEOMEED_01087	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLEOMEED_01088	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MLEOMEED_01089	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MLEOMEED_01090	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MLEOMEED_01091	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MLEOMEED_01092	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLEOMEED_01093	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_01094	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MLEOMEED_01095	1.57e-296	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLEOMEED_01096	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLEOMEED_01097	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLEOMEED_01098	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLEOMEED_01099	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MLEOMEED_01100	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MLEOMEED_01101	6.35e-201	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MLEOMEED_01102	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MLEOMEED_01103	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MLEOMEED_01104	1.07e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLEOMEED_01105	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MLEOMEED_01106	1.66e-267	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MLEOMEED_01107	5.16e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MLEOMEED_01108	7.2e-201	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MLEOMEED_01109	5.7e-281	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MLEOMEED_01110	3.68e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MLEOMEED_01111	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MLEOMEED_01112	2.26e-37	-	-	-	-	-	-	-	-
MLEOMEED_01113	1.77e-276	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLEOMEED_01115	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLEOMEED_01116	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MLEOMEED_01117	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MLEOMEED_01118	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MLEOMEED_01119	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MLEOMEED_01120	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLEOMEED_01121	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MLEOMEED_01122	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLEOMEED_01123	2.5e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLEOMEED_01124	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLEOMEED_01125	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLEOMEED_01126	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01127	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLEOMEED_01128	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLEOMEED_01129	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MLEOMEED_01130	9.25e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MLEOMEED_01131	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MLEOMEED_01132	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MLEOMEED_01133	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MLEOMEED_01134	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MLEOMEED_01135	6.93e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MLEOMEED_01136	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MLEOMEED_01137	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MLEOMEED_01138	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLEOMEED_01139	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MLEOMEED_01140	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MLEOMEED_01141	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MLEOMEED_01142	4.42e-222	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MLEOMEED_01143	5.18e-81	yqhP	-	-	-	-	-	-	-
MLEOMEED_01144	1.21e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MLEOMEED_01145	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLEOMEED_01146	1.12e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLEOMEED_01147	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MLEOMEED_01148	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLEOMEED_01149	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLEOMEED_01150	5.49e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MLEOMEED_01151	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLEOMEED_01152	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MLEOMEED_01153	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MLEOMEED_01154	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MLEOMEED_01155	1.28e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MLEOMEED_01156	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MLEOMEED_01157	2.29e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
MLEOMEED_01158	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MLEOMEED_01159	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
MLEOMEED_01160	2.55e-55	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MLEOMEED_01161	3.44e-65	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MLEOMEED_01162	4.35e-79	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MLEOMEED_01163	9.7e-94	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
MLEOMEED_01164	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MLEOMEED_01165	1.29e-220	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MLEOMEED_01166	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLEOMEED_01168	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MLEOMEED_01169	8.56e-307	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MLEOMEED_01170	1.06e-193	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLEOMEED_01172	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MLEOMEED_01173	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MLEOMEED_01174	5.52e-158	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MLEOMEED_01175	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MLEOMEED_01176	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MLEOMEED_01177	5.65e-258	yqgU	-	-	-	-	-	-	-
MLEOMEED_01178	1.06e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MLEOMEED_01179	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MLEOMEED_01180	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MLEOMEED_01181	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MLEOMEED_01182	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MLEOMEED_01183	3.38e-14	yqgO	-	-	-	-	-	-	-
MLEOMEED_01184	2.38e-138	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLEOMEED_01185	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MLEOMEED_01186	1.24e-260	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
MLEOMEED_01188	3.42e-68	yqzD	-	-	-	-	-	-	-
MLEOMEED_01189	2.92e-98	yqzC	-	-	S	-	-	-	YceG-like family
MLEOMEED_01190	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLEOMEED_01191	2.4e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLEOMEED_01192	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MLEOMEED_01193	7.43e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MLEOMEED_01194	4.51e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MLEOMEED_01195	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MLEOMEED_01196	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MLEOMEED_01197	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MLEOMEED_01198	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MLEOMEED_01199	9.27e-172	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MLEOMEED_01200	2.05e-99	yqgA	-	-	-	-	-	-	-
MLEOMEED_01201	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MLEOMEED_01202	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLEOMEED_01203	2.04e-81	yqfX	-	-	S	-	-	-	membrane
MLEOMEED_01204	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MLEOMEED_01205	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MLEOMEED_01206	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MLEOMEED_01207	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MLEOMEED_01208	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLEOMEED_01209	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLEOMEED_01210	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MLEOMEED_01211	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLEOMEED_01212	2.27e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLEOMEED_01213	2.41e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MLEOMEED_01214	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MLEOMEED_01215	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLEOMEED_01216	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLEOMEED_01217	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MLEOMEED_01218	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLEOMEED_01219	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
MLEOMEED_01220	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MLEOMEED_01221	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MLEOMEED_01222	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MLEOMEED_01223	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
MLEOMEED_01224	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLEOMEED_01225	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLEOMEED_01226	1.42e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MLEOMEED_01227	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLEOMEED_01228	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MLEOMEED_01230	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MLEOMEED_01231	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MLEOMEED_01232	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MLEOMEED_01233	3.13e-79	yqfB	-	-	-	-	-	-	-
MLEOMEED_01234	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
MLEOMEED_01235	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MLEOMEED_01236	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MLEOMEED_01237	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MLEOMEED_01238	3.45e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MLEOMEED_01239	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MLEOMEED_01240	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLEOMEED_01241	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MLEOMEED_01242	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLEOMEED_01243	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MLEOMEED_01244	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLEOMEED_01245	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLEOMEED_01246	4.3e-278	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MLEOMEED_01247	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLEOMEED_01248	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MLEOMEED_01249	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MLEOMEED_01250	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLEOMEED_01251	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MLEOMEED_01252	2.01e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MLEOMEED_01253	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
MLEOMEED_01254	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MLEOMEED_01255	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MLEOMEED_01256	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MLEOMEED_01257	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLEOMEED_01258	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
MLEOMEED_01259	9.76e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLEOMEED_01260	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MLEOMEED_01261	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLEOMEED_01262	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MLEOMEED_01263	8.44e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLEOMEED_01264	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLEOMEED_01265	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MLEOMEED_01267	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MLEOMEED_01268	7.45e-180	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MLEOMEED_01269	3.97e-136	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MLEOMEED_01270	7.95e-219	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MLEOMEED_01271	9.38e-171	-	-	-	-	-	-	-	-
MLEOMEED_01272	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MLEOMEED_01273	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_01274	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
MLEOMEED_01275	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MLEOMEED_01276	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
MLEOMEED_01277	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_01278	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
MLEOMEED_01279	2.08e-197	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MLEOMEED_01280	8.68e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
MLEOMEED_01283	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MLEOMEED_01284	1.66e-136	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
MLEOMEED_01286	5.4e-80	-	-	-	-	-	-	-	-
MLEOMEED_01288	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MLEOMEED_01289	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
MLEOMEED_01290	2.45e-213	xepA	-	-	-	-	-	-	-
MLEOMEED_01291	9.34e-33	-	-	-	-	-	-	-	-
MLEOMEED_01292	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
MLEOMEED_01293	2.91e-283	-	-	-	-	-	-	-	-
MLEOMEED_01294	3e-54	-	-	-	-	-	-	-	-
MLEOMEED_01295	4.58e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MLEOMEED_01296	1.31e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLEOMEED_01297	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MLEOMEED_01298	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MLEOMEED_01299	1.02e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
MLEOMEED_01300	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
MLEOMEED_01301	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MLEOMEED_01302	9.14e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MLEOMEED_01304	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MLEOMEED_01305	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MLEOMEED_01306	2.52e-36	-	-	-	-	-	-	-	-
MLEOMEED_01307	3.24e-102	yqbJ	-	-	-	-	-	-	-
MLEOMEED_01308	7.59e-123	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MLEOMEED_01309	7.08e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MLEOMEED_01310	7.09e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MLEOMEED_01311	2.47e-68	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
MLEOMEED_01312	9.21e-216	xkdG	-	-	S	-	-	-	Phage capsid family
MLEOMEED_01313	5.46e-186	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
MLEOMEED_01314	2.13e-149	-	-	-	-	-	-	-	-
MLEOMEED_01315	1.73e-217	-	-	-	S	-	-	-	Phage Mu protein F like protein
MLEOMEED_01316	0.0	yqbA	-	-	S	-	-	-	portal protein
MLEOMEED_01317	0.0	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MLEOMEED_01318	2.02e-158	yqaS	-	-	L	-	-	-	DNA packaging
MLEOMEED_01319	2.32e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF2705)
MLEOMEED_01320	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MLEOMEED_01321	1.06e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MLEOMEED_01322	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MLEOMEED_01323	5.39e-224	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MLEOMEED_01324	5.36e-148	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MLEOMEED_01325	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLEOMEED_01326	3.96e-177	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MLEOMEED_01327	1.79e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MLEOMEED_01328	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
MLEOMEED_01329	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_01330	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MLEOMEED_01331	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
MLEOMEED_01332	1.09e-205	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MLEOMEED_01334	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MLEOMEED_01335	4.9e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MLEOMEED_01336	7.65e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MLEOMEED_01337	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MLEOMEED_01338	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_01339	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLEOMEED_01340	1.18e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MLEOMEED_01341	6.74e-287	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLEOMEED_01342	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MLEOMEED_01343	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MLEOMEED_01344	7.14e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_01345	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MLEOMEED_01346	1.2e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MLEOMEED_01347	1.44e-165	yebC	-	-	M	-	-	-	Membrane
MLEOMEED_01349	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MLEOMEED_01350	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
MLEOMEED_01351	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLEOMEED_01352	9.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLEOMEED_01353	2.81e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLEOMEED_01354	1.06e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MLEOMEED_01355	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLEOMEED_01356	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLEOMEED_01357	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLEOMEED_01358	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLEOMEED_01359	1.4e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MLEOMEED_01360	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLEOMEED_01361	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MLEOMEED_01362	2.07e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MLEOMEED_01363	5.26e-96	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MLEOMEED_01364	1.91e-297	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MLEOMEED_01365	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MLEOMEED_01366	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MLEOMEED_01367	7.03e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MLEOMEED_01368	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01369	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MLEOMEED_01371	1.1e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLEOMEED_01372	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MLEOMEED_01373	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLEOMEED_01374	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MLEOMEED_01375	6.28e-253	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MLEOMEED_01376	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MLEOMEED_01377	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLEOMEED_01378	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLEOMEED_01379	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLEOMEED_01380	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLEOMEED_01381	2.93e-201	yerO	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01382	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLEOMEED_01383	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLEOMEED_01384	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLEOMEED_01385	3.63e-127	-	-	-	L	-	-	-	Recombinase
MLEOMEED_01386	5.61e-71	-	-	-	L	-	-	-	Resolvase, N terminal domain
MLEOMEED_01387	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MLEOMEED_01388	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
MLEOMEED_01389	1.13e-270	yeeC	-	-	P	-	-	-	T5orf172
MLEOMEED_01390	7.48e-05	-	-	-	-	-	-	-	-
MLEOMEED_01391	4.15e-42	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
MLEOMEED_01392	2.1e-109	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MLEOMEED_01393	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MLEOMEED_01394	1.73e-246	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
MLEOMEED_01395	1.33e-275	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
MLEOMEED_01397	1.09e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MLEOMEED_01399	1.86e-134	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_01400	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
MLEOMEED_01401	8.81e-206	yesF	-	-	GM	-	-	-	NAD(P)H-binding
MLEOMEED_01402	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MLEOMEED_01403	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MLEOMEED_01404	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MLEOMEED_01405	1.76e-132	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MLEOMEED_01407	3.52e-135	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
MLEOMEED_01408	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_01409	5.07e-260	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MLEOMEED_01410	8.76e-316	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MLEOMEED_01411	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_01412	1.31e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_01413	6.85e-255	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MLEOMEED_01414	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01415	3.56e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MLEOMEED_01416	1.41e-169	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
MLEOMEED_01417	3.44e-146	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MLEOMEED_01418	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MLEOMEED_01419	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MLEOMEED_01420	9.13e-160	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MLEOMEED_01421	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MLEOMEED_01422	0.0	yetA	-	-	-	-	-	-	-
MLEOMEED_01423	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MLEOMEED_01424	1.01e-227	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MLEOMEED_01425	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_01426	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MLEOMEED_01427	3.13e-158	yetF	-	-	S	-	-	-	membrane
MLEOMEED_01428	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MLEOMEED_01429	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_01430	9.79e-45	-	-	-	-	-	-	-	-
MLEOMEED_01431	3.87e-114	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLEOMEED_01432	1.97e-54	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLEOMEED_01433	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MLEOMEED_01434	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MLEOMEED_01435	7.35e-203	-	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_01436	6.74e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_01437	4.77e-270	yetM	-	-	CH	-	-	-	FAD binding domain
MLEOMEED_01438	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MLEOMEED_01439	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MLEOMEED_01440	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MLEOMEED_01441	2.15e-190	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MLEOMEED_01442	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MLEOMEED_01443	9.79e-232	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MLEOMEED_01444	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MLEOMEED_01445	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MLEOMEED_01446	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_01447	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MLEOMEED_01448	4.16e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MLEOMEED_01449	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLEOMEED_01450	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
MLEOMEED_01451	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLEOMEED_01452	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MLEOMEED_01453	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MLEOMEED_01454	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MLEOMEED_01455	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLEOMEED_01456	1.86e-266	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MLEOMEED_01457	1.86e-107	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MLEOMEED_01458	4.21e-242	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MLEOMEED_01459	8.15e-94	lrpA	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
MLEOMEED_01460	1.26e-101	lrpB	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
MLEOMEED_01461	1.62e-128	yddQ	-	-	Q	-	-	-	Isochorismatase family
MLEOMEED_01462	1.34e-184	yddR	-	-	S	-	-	-	Zn-dependent hydrolases of the beta-lactamase fold
MLEOMEED_01463	5.11e-49	ydaS	-	-	S	-	-	-	membrane
MLEOMEED_01464	7.62e-135	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MLEOMEED_01465	1.2e-204	-	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01466	1.53e-219	yrdR	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_01467	7.28e-25	-	-	-	S	-	-	-	YrzO-like protein
MLEOMEED_01468	1.58e-301	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MLEOMEED_01469	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MLEOMEED_01470	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MLEOMEED_01471	3.44e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MLEOMEED_01472	3.05e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLEOMEED_01473	3.64e-313	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_01474	9.1e-148	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MLEOMEED_01475	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MLEOMEED_01476	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MLEOMEED_01477	3.15e-278	xylR	-	-	GK	-	-	-	ROK family
MLEOMEED_01479	3.92e-76	-	-	-	K	-	-	-	Helix-turn-helix
MLEOMEED_01480	6.27e-51	-	-	-	S	-	-	-	TM2 domain
MLEOMEED_01481	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_01482	1.46e-58	yyaL	-	-	O	ko:K06888	-	ko00000	Highly conserved protein containing a thioredoxin domain
MLEOMEED_01483	1.34e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MLEOMEED_01484	1.99e-207	-	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_01485	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MLEOMEED_01486	8.91e-217	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MLEOMEED_01487	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
MLEOMEED_01488	3.26e-130	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MLEOMEED_01489	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_01490	3.03e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01491	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MLEOMEED_01492	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLEOMEED_01493	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLEOMEED_01494	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MLEOMEED_01495	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLEOMEED_01496	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLEOMEED_01497	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01498	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
MLEOMEED_01499	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MLEOMEED_01500	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MLEOMEED_01501	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MLEOMEED_01502	2.27e-98	-	-	-	S	-	-	-	Bacterial PH domain
MLEOMEED_01503	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLEOMEED_01504	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLEOMEED_01505	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLEOMEED_01506	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLEOMEED_01507	1.14e-149	yybJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MLEOMEED_01508	9.33e-226	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MLEOMEED_01509	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01511	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MLEOMEED_01512	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLEOMEED_01513	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MLEOMEED_01514	8.77e-184	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MLEOMEED_01515	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLEOMEED_01516	1.77e-32	yqzJ	-	-	-	-	-	-	-
MLEOMEED_01517	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLEOMEED_01518	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLEOMEED_01519	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLEOMEED_01520	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLEOMEED_01521	3.86e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLEOMEED_01522	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLEOMEED_01523	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MLEOMEED_01524	6.84e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLEOMEED_01525	3.98e-230	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MLEOMEED_01526	3.41e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_01527	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MLEOMEED_01528	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MLEOMEED_01529	1.33e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_01531	1.08e-289	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MLEOMEED_01533	4.03e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLEOMEED_01534	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
MLEOMEED_01535	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MLEOMEED_01536	5.51e-79	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MLEOMEED_01537	2.89e-251	yqkA	-	-	K	-	-	-	GrpB protein
MLEOMEED_01538	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MLEOMEED_01539	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MLEOMEED_01540	4.29e-227	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MLEOMEED_01541	1.78e-29	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MLEOMEED_01542	9.26e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MLEOMEED_01543	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MLEOMEED_01544	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MLEOMEED_01545	2.62e-283	yqxK	-	-	L	-	-	-	DNA helicase
MLEOMEED_01546	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01547	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MLEOMEED_01548	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MLEOMEED_01549	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MLEOMEED_01550	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MLEOMEED_01551	3.73e-44	yqkK	-	-	-	-	-	-	-
MLEOMEED_01552	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLEOMEED_01553	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MLEOMEED_01554	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MLEOMEED_01555	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MLEOMEED_01556	9.66e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLEOMEED_01557	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLEOMEED_01558	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MLEOMEED_01559	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MLEOMEED_01560	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLEOMEED_01561	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_01562	5.72e-144	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MLEOMEED_01563	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MLEOMEED_01564	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MLEOMEED_01565	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MLEOMEED_01566	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MLEOMEED_01567	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MLEOMEED_01568	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MLEOMEED_01569	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLEOMEED_01570	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
MLEOMEED_01571	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLEOMEED_01573	3.82e-09	-	-	-	S	-	-	-	SNARE associated Golgi protein
MLEOMEED_01575	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
MLEOMEED_01576	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MLEOMEED_01577	2.96e-72	ypuD	-	-	-	-	-	-	-
MLEOMEED_01578	1.77e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLEOMEED_01579	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MLEOMEED_01580	3.12e-292	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLEOMEED_01581	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLEOMEED_01582	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_01583	3.18e-123	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MLEOMEED_01584	1.33e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLEOMEED_01585	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLEOMEED_01586	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MLEOMEED_01587	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MLEOMEED_01588	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MLEOMEED_01589	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MLEOMEED_01590	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MLEOMEED_01591	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLEOMEED_01592	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MLEOMEED_01593	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLEOMEED_01594	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_01595	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_01596	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_01597	2.7e-257	rsiX	-	-	-	-	-	-	-
MLEOMEED_01598	2.89e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLEOMEED_01599	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLEOMEED_01600	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLEOMEED_01601	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MLEOMEED_01602	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MLEOMEED_01603	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MLEOMEED_01604	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MLEOMEED_01605	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
MLEOMEED_01606	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MLEOMEED_01607	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MLEOMEED_01608	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLEOMEED_01609	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MLEOMEED_01610	1.62e-227	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MLEOMEED_01611	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MLEOMEED_01612	4.88e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MLEOMEED_01613	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MLEOMEED_01614	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MLEOMEED_01615	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MLEOMEED_01616	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MLEOMEED_01617	9.5e-263	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MLEOMEED_01618	8.41e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLEOMEED_01619	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
MLEOMEED_01620	2.73e-134	yphA	-	-	-	-	-	-	-
MLEOMEED_01621	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
MLEOMEED_01622	8.69e-40	ypzH	-	-	-	-	-	-	-
MLEOMEED_01623	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MLEOMEED_01624	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MLEOMEED_01625	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MLEOMEED_01626	9.07e-178	yphF	-	-	-	-	-	-	-
MLEOMEED_01627	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLEOMEED_01628	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLEOMEED_01629	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MLEOMEED_01630	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLEOMEED_01631	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLEOMEED_01632	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLEOMEED_01633	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MLEOMEED_01634	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLEOMEED_01635	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MLEOMEED_01636	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLEOMEED_01637	8.48e-265	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLEOMEED_01638	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLEOMEED_01639	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLEOMEED_01640	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLEOMEED_01641	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MLEOMEED_01642	2.82e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MLEOMEED_01643	9.33e-295	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLEOMEED_01644	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLEOMEED_01645	4.5e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLEOMEED_01646	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MLEOMEED_01647	9.91e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLEOMEED_01648	5.27e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MLEOMEED_01649	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MLEOMEED_01650	4.75e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MLEOMEED_01651	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MLEOMEED_01652	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MLEOMEED_01653	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MLEOMEED_01654	2.82e-126	ypjA	-	-	S	-	-	-	membrane
MLEOMEED_01655	6.84e-183	ypjB	-	-	S	-	-	-	sporulation protein
MLEOMEED_01656	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MLEOMEED_01657	5.83e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MLEOMEED_01658	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLEOMEED_01659	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MLEOMEED_01660	6.61e-167	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MLEOMEED_01661	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLEOMEED_01662	1.41e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLEOMEED_01663	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLEOMEED_01664	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLEOMEED_01665	1.34e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLEOMEED_01666	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLEOMEED_01667	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MLEOMEED_01668	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MLEOMEED_01669	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01670	1.07e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MLEOMEED_01671	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MLEOMEED_01672	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MLEOMEED_01673	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLEOMEED_01674	1.43e-121	ypoC	-	-	-	-	-	-	-
MLEOMEED_01675	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MLEOMEED_01676	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLEOMEED_01677	4.54e-241	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MLEOMEED_01680	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MLEOMEED_01681	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
MLEOMEED_01682	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
MLEOMEED_01683	4.33e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MLEOMEED_01684	2.34e-113	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MLEOMEED_01685	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLEOMEED_01686	7.21e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MLEOMEED_01687	3.41e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MLEOMEED_01688	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLEOMEED_01689	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MLEOMEED_01691	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MLEOMEED_01692	2.05e-179	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_01693	1.25e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MLEOMEED_01694	1.92e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MLEOMEED_01695	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MLEOMEED_01696	2.53e-133	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MLEOMEED_01697	1e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MLEOMEED_01698	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLEOMEED_01699	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLEOMEED_01700	3.14e-294	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MLEOMEED_01701	4.55e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MLEOMEED_01702	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MLEOMEED_01703	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MLEOMEED_01704	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MLEOMEED_01705	1.08e-11	-	-	-	-	-	-	-	-
MLEOMEED_01706	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
MLEOMEED_01707	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
MLEOMEED_01708	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MLEOMEED_01709	2.4e-138	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLEOMEED_01710	4e-163	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MLEOMEED_01711	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
MLEOMEED_01712	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MLEOMEED_01713	1.17e-22	degR	-	-	-	-	-	-	-
MLEOMEED_01714	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MLEOMEED_01715	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLEOMEED_01716	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLEOMEED_01717	1.89e-115	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MLEOMEED_01718	2.52e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MLEOMEED_01719	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MLEOMEED_01720	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MLEOMEED_01721	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MLEOMEED_01722	6.15e-187	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MLEOMEED_01723	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MLEOMEED_01724	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MLEOMEED_01725	7.27e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLEOMEED_01726	1.21e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLEOMEED_01727	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLEOMEED_01728	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MLEOMEED_01729	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01730	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLEOMEED_01731	1.49e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MLEOMEED_01732	2.77e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLEOMEED_01733	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MLEOMEED_01734	6.8e-129	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01735	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
MLEOMEED_01736	3.49e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
MLEOMEED_01737	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
MLEOMEED_01738	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLEOMEED_01739	3.52e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MLEOMEED_01740	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MLEOMEED_01741	4.17e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MLEOMEED_01742	2.95e-240	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MLEOMEED_01743	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
MLEOMEED_01744	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
MLEOMEED_01745	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MLEOMEED_01746	2.06e-186	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MLEOMEED_01749	0.0	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLEOMEED_01751	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLEOMEED_01752	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MLEOMEED_01753	9.5e-200	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MLEOMEED_01754	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MLEOMEED_01755	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MLEOMEED_01756	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MLEOMEED_01757	3.84e-161	yodN	-	-	-	-	-	-	-
MLEOMEED_01759	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
MLEOMEED_01760	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MLEOMEED_01761	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
MLEOMEED_01762	2.08e-12	-	-	-	-	-	-	-	-
MLEOMEED_01763	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MLEOMEED_01764	1.62e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MLEOMEED_01765	2.93e-42	yodI	-	-	-	-	-	-	-
MLEOMEED_01766	6.38e-168	yodH	-	-	Q	-	-	-	Methyltransferase
MLEOMEED_01767	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MLEOMEED_01768	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLEOMEED_01769	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MLEOMEED_01770	1.18e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MLEOMEED_01771	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MLEOMEED_01772	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
MLEOMEED_01773	1.37e-76	yodB	-	-	K	-	-	-	transcriptional
MLEOMEED_01774	2.05e-86	iolK	-	-	S	-	-	-	tautomerase
MLEOMEED_01775	1.01e-293	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MLEOMEED_01776	1.95e-14	-	-	-	-	-	-	-	-
MLEOMEED_01777	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MLEOMEED_01778	1.21e-209	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MLEOMEED_01779	1.85e-58	-	-	-	-	-	-	-	-
MLEOMEED_01780	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MLEOMEED_01781	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MLEOMEED_01782	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLEOMEED_01783	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MLEOMEED_01785	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLEOMEED_01786	5.62e-294	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MLEOMEED_01787	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MLEOMEED_01788	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLEOMEED_01789	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MLEOMEED_01790	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MLEOMEED_01791	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLEOMEED_01792	3.16e-265	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLEOMEED_01793	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MLEOMEED_01794	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLEOMEED_01795	3.35e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MLEOMEED_01796	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MLEOMEED_01797	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MLEOMEED_01798	1.91e-42	yozC	-	-	-	-	-	-	-
MLEOMEED_01799	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
MLEOMEED_01800	1.83e-49	yocN	-	-	-	-	-	-	-
MLEOMEED_01801	2.94e-55	yozN	-	-	-	-	-	-	-
MLEOMEED_01802	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MLEOMEED_01803	7.29e-46	-	-	-	-	-	-	-	-
MLEOMEED_01804	3.02e-70	yocL	-	-	-	-	-	-	-
MLEOMEED_01805	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
MLEOMEED_01806	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLEOMEED_01807	1.49e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_01808	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MLEOMEED_01809	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLEOMEED_01810	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MLEOMEED_01811	5.43e-52	ykoA	-	-	-	-	-	-	-
MLEOMEED_01812	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLEOMEED_01813	2.99e-217	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLEOMEED_01814	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLEOMEED_01815	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MLEOMEED_01816	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MLEOMEED_01817	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MLEOMEED_01818	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MLEOMEED_01819	9.21e-208	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MLEOMEED_01820	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MLEOMEED_01821	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLEOMEED_01822	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLEOMEED_01823	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MLEOMEED_01824	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MLEOMEED_01825	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLEOMEED_01826	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MLEOMEED_01827	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MLEOMEED_01828	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLEOMEED_01829	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLEOMEED_01830	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLEOMEED_01831	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLEOMEED_01832	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MLEOMEED_01833	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MLEOMEED_01834	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MLEOMEED_01835	1.3e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MLEOMEED_01836	4.48e-35	ykzI	-	-	-	-	-	-	-
MLEOMEED_01837	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MLEOMEED_01838	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MLEOMEED_01839	1.28e-223	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLEOMEED_01840	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MLEOMEED_01841	0.0	ylaA	-	-	-	-	-	-	-
MLEOMEED_01842	1.44e-56	ylaB	-	-	-	-	-	-	-
MLEOMEED_01843	4.51e-118	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_01845	1.74e-57	ylaE	-	-	-	-	-	-	-
MLEOMEED_01846	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MLEOMEED_01847	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MLEOMEED_01848	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
MLEOMEED_01849	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01850	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLEOMEED_01851	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MLEOMEED_01852	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLEOMEED_01853	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MLEOMEED_01854	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MLEOMEED_01855	2.57e-273	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MLEOMEED_01856	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLEOMEED_01857	2.97e-214	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLEOMEED_01858	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLEOMEED_01859	5.85e-253	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLEOMEED_01860	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLEOMEED_01861	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLEOMEED_01862	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLEOMEED_01863	1.04e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MLEOMEED_01864	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
MLEOMEED_01865	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MLEOMEED_01866	4.58e-258	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MLEOMEED_01867	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
MLEOMEED_01868	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MLEOMEED_01869	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MLEOMEED_01870	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
MLEOMEED_01871	2.12e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MLEOMEED_01872	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLEOMEED_01873	2.73e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MLEOMEED_01874	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MLEOMEED_01875	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MLEOMEED_01876	5.94e-301	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MLEOMEED_01878	1.7e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MLEOMEED_01879	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MLEOMEED_01880	5.75e-108	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLEOMEED_01881	3.26e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
MLEOMEED_01882	1.66e-216	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLEOMEED_01883	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLEOMEED_01884	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MLEOMEED_01885	4.97e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLEOMEED_01886	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MLEOMEED_01887	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MLEOMEED_01888	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MLEOMEED_01889	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLEOMEED_01890	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLEOMEED_01891	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLEOMEED_01892	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MLEOMEED_01893	9.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLEOMEED_01894	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MLEOMEED_01895	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLEOMEED_01896	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01897	1.06e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_01898	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
MLEOMEED_01899	3.58e-202	-	-	-	-	-	-	-	-
MLEOMEED_01900	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MLEOMEED_01901	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLEOMEED_01902	4.3e-136	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MLEOMEED_01903	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
MLEOMEED_01904	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MLEOMEED_01905	2.21e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MLEOMEED_01906	5.23e-175	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MLEOMEED_01907	1.29e-183	-	-	-	J	-	-	-	FR47-like protein
MLEOMEED_01908	9.22e-129	yobS	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01909	1.34e-169	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MLEOMEED_01910	1.55e-114	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MLEOMEED_01911	2.05e-229	yobV	-	-	K	-	-	-	WYL domain
MLEOMEED_01912	2.21e-122	yobW	-	-	-	-	-	-	-
MLEOMEED_01913	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MLEOMEED_01914	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLEOMEED_01915	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MLEOMEED_01916	4.49e-186	-	-	-	-	-	-	-	-
MLEOMEED_01917	1.32e-122	yocC	-	-	-	-	-	-	-
MLEOMEED_01918	1.21e-243	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MLEOMEED_01919	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MLEOMEED_01920	1.22e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_01921	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_01922	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MLEOMEED_01923	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MLEOMEED_01924	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLEOMEED_01925	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLEOMEED_01926	6.01e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MLEOMEED_01927	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MLEOMEED_01928	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MLEOMEED_01929	5.12e-112	ytrI	-	-	-	-	-	-	-
MLEOMEED_01930	1.15e-39	-	-	-	-	-	-	-	-
MLEOMEED_01931	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MLEOMEED_01932	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MLEOMEED_01933	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MLEOMEED_01934	2.24e-206	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MLEOMEED_01935	2.09e-306	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MLEOMEED_01936	1.69e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
MLEOMEED_01937	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_01938	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MLEOMEED_01939	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_01940	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MLEOMEED_01941	4.08e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_01942	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MLEOMEED_01943	4.01e-194	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MLEOMEED_01944	3.18e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MLEOMEED_01945	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MLEOMEED_01946	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MLEOMEED_01947	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MLEOMEED_01948	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_01950	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MLEOMEED_01951	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLEOMEED_01952	8.14e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MLEOMEED_01953	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLEOMEED_01954	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MLEOMEED_01955	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLEOMEED_01956	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MLEOMEED_01957	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MLEOMEED_01958	7.05e-113	yteJ	-	-	S	-	-	-	RDD family
MLEOMEED_01959	6.13e-233	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MLEOMEED_01960	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLEOMEED_01961	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MLEOMEED_01962	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLEOMEED_01963	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MLEOMEED_01964	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLEOMEED_01965	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MLEOMEED_01966	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MLEOMEED_01967	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLEOMEED_01968	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLEOMEED_01969	2.94e-142	yttP	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_01970	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MLEOMEED_01971	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MLEOMEED_01972	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLEOMEED_01974	6.47e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLEOMEED_01975	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLEOMEED_01976	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLEOMEED_01977	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MLEOMEED_01978	6.51e-293	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MLEOMEED_01979	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MLEOMEED_01980	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MLEOMEED_01981	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MLEOMEED_01982	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLEOMEED_01983	1.9e-72	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MLEOMEED_01984	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MLEOMEED_01985	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLEOMEED_01986	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MLEOMEED_01987	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MLEOMEED_01988	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLEOMEED_01989	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MLEOMEED_01990	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MLEOMEED_01991	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MLEOMEED_01992	2.24e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MLEOMEED_01993	4.06e-68	ytzB	-	-	S	-	-	-	small secreted protein
MLEOMEED_01994	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MLEOMEED_01995	2.16e-193	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MLEOMEED_01996	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLEOMEED_01997	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
MLEOMEED_01998	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
MLEOMEED_01999	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MLEOMEED_02000	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MLEOMEED_02001	4.92e-212	ytlQ	-	-	-	-	-	-	-
MLEOMEED_02002	7.71e-133	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLEOMEED_02003	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MLEOMEED_02004	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MLEOMEED_02005	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MLEOMEED_02006	8.45e-263	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MLEOMEED_02007	2.4e-169	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MLEOMEED_02008	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MLEOMEED_02009	9.04e-171	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MLEOMEED_02010	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_02011	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MLEOMEED_02012	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MLEOMEED_02013	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MLEOMEED_02014	1.97e-152	yteU	-	-	S	-	-	-	Integral membrane protein
MLEOMEED_02015	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MLEOMEED_02016	5.81e-95	yteS	-	-	G	-	-	-	transport
MLEOMEED_02017	2.23e-286	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MLEOMEED_02018	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MLEOMEED_02019	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02020	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MLEOMEED_02021	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MLEOMEED_02022	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MLEOMEED_02023	2.64e-287	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MLEOMEED_02024	4.57e-244	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLEOMEED_02025	5.04e-164	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLEOMEED_02026	3.73e-284	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLEOMEED_02027	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLEOMEED_02028	4.04e-182	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLEOMEED_02029	1.43e-222	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
MLEOMEED_02030	1.29e-113	yrdC	-	-	Q	-	-	-	Isochorismatase family
MLEOMEED_02034	3.89e-66	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MLEOMEED_02035	0.000611	-	-	-	-	-	-	-	-
MLEOMEED_02036	6.08e-12	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MLEOMEED_02037	4.39e-30	-	-	-	-	-	-	-	-
MLEOMEED_02038	1.63e-212	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
MLEOMEED_02039	1.96e-17	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
MLEOMEED_02040	2.28e-108	-	-	-	L	-	-	-	DnaD domain protein
MLEOMEED_02043	9.02e-105	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
MLEOMEED_02045	1.48e-31	-	-	-	-	-	-	-	-
MLEOMEED_02047	1.14e-33	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MLEOMEED_02048	6.02e-55	-	-	-	E	-	-	-	Zn peptidase
MLEOMEED_02049	4.49e-170	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MLEOMEED_02050	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MLEOMEED_02051	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MLEOMEED_02052	5.82e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLEOMEED_02053	4.47e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLEOMEED_02054	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MLEOMEED_02055	4.93e-151	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MLEOMEED_02056	2.24e-141	-	-	-	-	-	-	-	-
MLEOMEED_02057	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLEOMEED_02058	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLEOMEED_02059	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MLEOMEED_02060	1.2e-30	ymzA	-	-	-	-	-	-	-
MLEOMEED_02061	8.07e-32	-	-	-	-	-	-	-	-
MLEOMEED_02062	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLEOMEED_02063	9.69e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLEOMEED_02064	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
MLEOMEED_02066	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MLEOMEED_02067	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
MLEOMEED_02068	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MLEOMEED_02069	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
MLEOMEED_02070	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MLEOMEED_02071	4.8e-210	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MLEOMEED_02072	2.8e-81	ymzB	-	-	-	-	-	-	-
MLEOMEED_02073	2.49e-297	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MLEOMEED_02074	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MLEOMEED_02075	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MLEOMEED_02076	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MLEOMEED_02077	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MLEOMEED_02078	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MLEOMEED_02079	2.69e-177	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MLEOMEED_02080	2.48e-184	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MLEOMEED_02081	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MLEOMEED_02082	5.31e-304	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLEOMEED_02083	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MLEOMEED_02084	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MLEOMEED_02085	2.08e-239	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MLEOMEED_02086	1.31e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MLEOMEED_02087	7.53e-133	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MLEOMEED_02089	6.17e-158	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLEOMEED_02090	1.52e-79	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLEOMEED_02091	2.05e-51	-	-	-	S	-	-	-	YolD-like protein
MLEOMEED_02092	2.08e-64	-	-	-	-	-	-	-	-
MLEOMEED_02095	1.06e-80	ynaF	-	-	-	-	-	-	-
MLEOMEED_02096	1.65e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MLEOMEED_02097	7.56e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_02098	1.97e-186	ynaC	-	-	-	-	-	-	-
MLEOMEED_02099	5.4e-105	-	-	-	G	-	-	-	regulation of fungal-type cell wall biogenesis
MLEOMEED_02100	7.13e-52	-	-	-	-	-	-	-	-
MLEOMEED_02101	2.61e-40	-	-	-	-	-	-	-	-
MLEOMEED_02102	2.95e-14	-	-	-	-	-	-	-	-
MLEOMEED_02106	3.38e-138	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MLEOMEED_02107	1.45e-243	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MLEOMEED_02108	9.44e-85	-	-	-	S	-	-	-	Immunity protein 70
MLEOMEED_02109	1.07e-160	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MLEOMEED_02110	6.25e-75	-	-	-	S	-	-	-	Bacteriophage holin family
MLEOMEED_02113	3.21e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MLEOMEED_02114	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
MLEOMEED_02115	7.09e-278	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
MLEOMEED_02116	2.06e-143	-	-	-	S	-	-	-	Phage tail protein
MLEOMEED_02117	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
MLEOMEED_02120	5.6e-102	-	-	-	S	-	-	-	Phage tail tube protein
MLEOMEED_02122	3.42e-66	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MLEOMEED_02123	3.02e-51	-	-	-	S	-	-	-	Phage head-tail joining protein
MLEOMEED_02124	9.84e-51	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MLEOMEED_02125	3.8e-34	-	-	-	-	-	-	-	-
MLEOMEED_02126	4.29e-201	-	-	-	S	-	-	-	capsid protein
MLEOMEED_02127	3.75e-102	-	-	-	S	-	-	-	peptidase activity
MLEOMEED_02128	5.52e-220	-	-	-	S	-	-	-	Phage portal protein
MLEOMEED_02129	0.0	-	-	-	S	-	-	-	Terminase
MLEOMEED_02130	2.11e-101	-	-	-	L	-	-	-	phage terminase small subunit
MLEOMEED_02134	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
MLEOMEED_02135	2.25e-131	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MLEOMEED_02136	1.42e-78	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_02137	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLEOMEED_02138	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MLEOMEED_02139	2.58e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLEOMEED_02140	1.03e-146	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MLEOMEED_02141	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MLEOMEED_02142	1.58e-105	yqaQ	-	-	L	-	-	-	Transposase
MLEOMEED_02143	5.43e-05	-	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase-like
MLEOMEED_02144	2.13e-127	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MLEOMEED_02145	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLEOMEED_02146	2.06e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MLEOMEED_02147	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLEOMEED_02148	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
MLEOMEED_02149	3.82e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MLEOMEED_02159	2.43e-241	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_02160	2.93e-212	-	-	-	-	-	-	-	-
MLEOMEED_02162	5.17e-92	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MLEOMEED_02163	1.14e-173	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MLEOMEED_02165	5.21e-123	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLEOMEED_02167	7.03e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLEOMEED_02169	1.55e-172	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MLEOMEED_02172	8.23e-117	ysxD	-	-	-	-	-	-	-
MLEOMEED_02173	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLEOMEED_02174	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MLEOMEED_02175	2.66e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLEOMEED_02176	1.57e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MLEOMEED_02177	6.39e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MLEOMEED_02178	8.99e-315	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MLEOMEED_02179	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MLEOMEED_02180	2.91e-253	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLEOMEED_02181	1.53e-35	-	-	-	-	-	-	-	-
MLEOMEED_02182	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLEOMEED_02183	5.8e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MLEOMEED_02184	3.15e-109	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLEOMEED_02185	4.67e-215	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MLEOMEED_02186	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MLEOMEED_02187	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MLEOMEED_02188	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MLEOMEED_02189	1.91e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MLEOMEED_02190	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MLEOMEED_02191	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLEOMEED_02192	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MLEOMEED_02193	1.83e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MLEOMEED_02194	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MLEOMEED_02195	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MLEOMEED_02196	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MLEOMEED_02197	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MLEOMEED_02198	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MLEOMEED_02199	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLEOMEED_02200	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MLEOMEED_02201	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MLEOMEED_02202	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MLEOMEED_02203	1.27e-294	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MLEOMEED_02204	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MLEOMEED_02205	8.17e-208	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MLEOMEED_02206	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLEOMEED_02207	1.71e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MLEOMEED_02208	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLEOMEED_02209	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MLEOMEED_02210	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MLEOMEED_02211	2.42e-47	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
MLEOMEED_02213	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
MLEOMEED_02214	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MLEOMEED_02215	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
MLEOMEED_02216	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MLEOMEED_02217	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLEOMEED_02218	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLEOMEED_02219	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MLEOMEED_02220	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLEOMEED_02221	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLEOMEED_02222	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MLEOMEED_02223	1.07e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MLEOMEED_02224	6.34e-147	yrbG	-	-	S	-	-	-	membrane
MLEOMEED_02225	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_02226	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MLEOMEED_02227	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLEOMEED_02228	6.51e-114	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MLEOMEED_02229	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MLEOMEED_02230	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MLEOMEED_02231	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLEOMEED_02232	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLEOMEED_02233	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLEOMEED_02234	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MLEOMEED_02236	1.27e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MLEOMEED_02237	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLEOMEED_02238	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLEOMEED_02239	8.5e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLEOMEED_02240	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_02241	2.67e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MLEOMEED_02242	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLEOMEED_02243	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MLEOMEED_02244	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLEOMEED_02245	1.23e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02246	8.4e-42	yrzR	-	-	-	-	-	-	-
MLEOMEED_02247	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MLEOMEED_02248	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_02249	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_02250	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MLEOMEED_02251	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MLEOMEED_02252	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
MLEOMEED_02253	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLEOMEED_02254	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MLEOMEED_02255	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLEOMEED_02256	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MLEOMEED_02257	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLEOMEED_02258	1.7e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MLEOMEED_02259	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MLEOMEED_02260	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MLEOMEED_02261	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MLEOMEED_02262	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLEOMEED_02263	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MLEOMEED_02264	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MLEOMEED_02265	8.52e-37	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MLEOMEED_02266	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLEOMEED_02267	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLEOMEED_02268	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MLEOMEED_02269	4.24e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MLEOMEED_02270	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
MLEOMEED_02271	4.26e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MLEOMEED_02272	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MLEOMEED_02273	1.08e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MLEOMEED_02274	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MLEOMEED_02276	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MLEOMEED_02277	1.1e-126	yrhH	-	-	Q	-	-	-	methyltransferase
MLEOMEED_02278	1.12e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MLEOMEED_02279	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MLEOMEED_02280	2.67e-62	yrhK	-	-	S	-	-	-	YrhK-like protein
MLEOMEED_02281	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MLEOMEED_02282	3.67e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MLEOMEED_02283	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_02284	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
MLEOMEED_02285	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
MLEOMEED_02286	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_02287	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
MLEOMEED_02288	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MLEOMEED_02289	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
MLEOMEED_02290	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MLEOMEED_02291	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MLEOMEED_02292	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MLEOMEED_02293	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MLEOMEED_02294	4.3e-256	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MLEOMEED_02295	3.03e-40	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
MLEOMEED_02296	3.17e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MLEOMEED_02297	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MLEOMEED_02298	1.05e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
MLEOMEED_02299	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLEOMEED_02300	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
MLEOMEED_02301	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
MLEOMEED_02302	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
MLEOMEED_02303	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
MLEOMEED_02304	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
MLEOMEED_02305	4.9e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
MLEOMEED_02306	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_02307	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLEOMEED_02309	7.25e-264	yraM	-	-	S	-	-	-	PrpF protein
MLEOMEED_02310	5.13e-211	yraN	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02311	9.19e-287	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MLEOMEED_02312	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
MLEOMEED_02313	1.1e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_02314	9.28e-170	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MLEOMEED_02316	5.87e-163	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MLEOMEED_02317	8.73e-191	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MLEOMEED_02318	3.79e-249	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLEOMEED_02319	2.66e-215	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MLEOMEED_02320	1.47e-120	yrdA	-	-	S	-	-	-	DinB family
MLEOMEED_02321	2.28e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MLEOMEED_02322	7.37e-133	yrdC	-	-	Q	-	-	-	Isochorismatase family
MLEOMEED_02324	1.75e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MLEOMEED_02325	1.07e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MLEOMEED_02326	1.44e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
MLEOMEED_02327	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
MLEOMEED_02328	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MLEOMEED_02329	7.09e-292	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MLEOMEED_02331	2e-207	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MLEOMEED_02332	1.98e-20	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLEOMEED_02333	5.74e-221	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLEOMEED_02334	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MLEOMEED_02335	2.89e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLEOMEED_02336	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MLEOMEED_02337	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_02338	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
MLEOMEED_02339	1.19e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MLEOMEED_02340	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MLEOMEED_02341	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
MLEOMEED_02342	4.03e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
MLEOMEED_02343	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MLEOMEED_02344	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MLEOMEED_02345	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLEOMEED_02346	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLEOMEED_02348	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_02349	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MLEOMEED_02350	4.28e-72	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MLEOMEED_02351	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MLEOMEED_02352	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MLEOMEED_02353	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLEOMEED_02354	7.89e-254	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MLEOMEED_02355	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MLEOMEED_02356	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
MLEOMEED_02357	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MLEOMEED_02358	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MLEOMEED_02359	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MLEOMEED_02360	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MLEOMEED_02361	3.88e-140	yvgT	-	-	S	-	-	-	membrane
MLEOMEED_02362	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MLEOMEED_02363	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLEOMEED_02364	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLEOMEED_02365	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MLEOMEED_02366	7.97e-113	yvgO	-	-	-	-	-	-	-
MLEOMEED_02367	4.54e-203	yvgN	-	-	S	-	-	-	reductase
MLEOMEED_02368	6.08e-154	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MLEOMEED_02369	6.57e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MLEOMEED_02370	5.58e-218	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MLEOMEED_02371	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MLEOMEED_02372	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MLEOMEED_02373	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MLEOMEED_02374	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MLEOMEED_02376	1.14e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_02377	1.48e-237	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_02378	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_02379	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MLEOMEED_02380	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
MLEOMEED_02381	1.62e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_02382	1.17e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MLEOMEED_02383	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MLEOMEED_02384	1.59e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MLEOMEED_02385	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
MLEOMEED_02386	6.74e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MLEOMEED_02387	5.07e-32	-	-	-	-	-	-	-	-
MLEOMEED_02388	2.08e-169	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_02389	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MLEOMEED_02390	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MLEOMEED_02391	5.21e-182	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_02392	5.15e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MLEOMEED_02393	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_02394	0.0	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLEOMEED_02395	8.21e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MLEOMEED_02396	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_02397	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MLEOMEED_02398	4.22e-144	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLEOMEED_02399	6.57e-178	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MLEOMEED_02400	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MLEOMEED_02401	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_02402	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_02403	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MLEOMEED_02404	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MLEOMEED_02405	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MLEOMEED_02406	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MLEOMEED_02407	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLEOMEED_02408	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02409	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02410	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MLEOMEED_02411	3.39e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MLEOMEED_02412	3.98e-169	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MLEOMEED_02413	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
MLEOMEED_02414	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MLEOMEED_02415	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLEOMEED_02416	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MLEOMEED_02417	3.23e-121	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MLEOMEED_02418	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MLEOMEED_02419	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLEOMEED_02420	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MLEOMEED_02421	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MLEOMEED_02422	1.32e-57	ywjC	-	-	-	-	-	-	-
MLEOMEED_02423	4.88e-236	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLEOMEED_02424	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLEOMEED_02425	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MLEOMEED_02426	2.1e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
MLEOMEED_02427	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLEOMEED_02428	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLEOMEED_02429	3.31e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MLEOMEED_02430	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MLEOMEED_02431	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MLEOMEED_02432	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLEOMEED_02433	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLEOMEED_02434	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MLEOMEED_02435	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLEOMEED_02436	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MLEOMEED_02437	8.53e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MLEOMEED_02438	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MLEOMEED_02439	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MLEOMEED_02440	6.26e-119	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLEOMEED_02441	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLEOMEED_02442	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLEOMEED_02443	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLEOMEED_02445	1.67e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MLEOMEED_02446	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MLEOMEED_02447	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MLEOMEED_02448	4.44e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLEOMEED_02449	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MLEOMEED_02450	5.75e-103	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLEOMEED_02451	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MLEOMEED_02452	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MLEOMEED_02453	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLEOMEED_02454	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLEOMEED_02455	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MLEOMEED_02456	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MLEOMEED_02457	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLEOMEED_02458	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLEOMEED_02459	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLEOMEED_02460	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLEOMEED_02461	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLEOMEED_02462	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLEOMEED_02463	1.04e-76	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MLEOMEED_02464	6.12e-115	ywmA	-	-	-	-	-	-	-
MLEOMEED_02465	4.54e-45	ywzB	-	-	S	-	-	-	membrane
MLEOMEED_02466	2.39e-174	ywmB	-	-	S	-	-	-	TATA-box binding
MLEOMEED_02467	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLEOMEED_02468	3.72e-238	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MLEOMEED_02469	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MLEOMEED_02470	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MLEOMEED_02472	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLEOMEED_02473	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLEOMEED_02474	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MLEOMEED_02475	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
MLEOMEED_02476	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
MLEOMEED_02477	1.15e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MLEOMEED_02478	2.75e-11	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MLEOMEED_02480	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MLEOMEED_02481	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MLEOMEED_02482	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLEOMEED_02483	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLEOMEED_02484	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLEOMEED_02485	1.55e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLEOMEED_02486	1.44e-127	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MLEOMEED_02487	7.7e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MLEOMEED_02488	2.43e-150	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MLEOMEED_02489	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MLEOMEED_02491	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLEOMEED_02492	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLEOMEED_02493	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLEOMEED_02494	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MLEOMEED_02495	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLEOMEED_02496	4.5e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
MLEOMEED_02497	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
MLEOMEED_02498	9.63e-08	-	-	-	-	-	-	-	-
MLEOMEED_02499	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MLEOMEED_02500	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLEOMEED_02501	5.65e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MLEOMEED_02502	1.32e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MLEOMEED_02503	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
MLEOMEED_02504	1.23e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MLEOMEED_02505	4.72e-245	yueF	-	-	S	-	-	-	transporter activity
MLEOMEED_02506	3.97e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
MLEOMEED_02507	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MLEOMEED_02508	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MLEOMEED_02509	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_02510	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MLEOMEED_02511	2.1e-253	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MLEOMEED_02515	3.35e-288	ydeG3	-	-	EGP	-	-	-	Major Facilitator Superfamily
MLEOMEED_02516	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_02517	2.79e-102	ygaO	-	-	-	-	-	-	-
MLEOMEED_02518	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLEOMEED_02520	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MLEOMEED_02521	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLEOMEED_02522	1.78e-219	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MLEOMEED_02523	4.15e-185	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLEOMEED_02524	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MLEOMEED_02526	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MLEOMEED_02527	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLEOMEED_02528	6.95e-173	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MLEOMEED_02529	3.88e-37	-	-	-	-	-	-	-	-
MLEOMEED_02530	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
MLEOMEED_02547	1.17e-216	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_02548	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MLEOMEED_02549	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MLEOMEED_02550	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_02551	1.33e-67	-	-	-	-	-	-	-	-
MLEOMEED_02552	9.25e-103	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
MLEOMEED_02553	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MLEOMEED_02554	2.3e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
MLEOMEED_02555	1.88e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MLEOMEED_02556	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MLEOMEED_02557	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLEOMEED_02558	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MLEOMEED_02559	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLEOMEED_02560	2.44e-303	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MLEOMEED_02561	4.85e-231	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLEOMEED_02562	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MLEOMEED_02563	4.9e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MLEOMEED_02564	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLEOMEED_02565	1.44e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLEOMEED_02566	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLEOMEED_02567	9.11e-198	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
MLEOMEED_02568	4.86e-259	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
MLEOMEED_02569	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MLEOMEED_02570	5.21e-275	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MLEOMEED_02571	1.67e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_02572	1.81e-149	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MLEOMEED_02573	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MLEOMEED_02574	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_02575	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_02577	2.17e-243	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MLEOMEED_02578	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MLEOMEED_02581	7.32e-42	yxeE	-	-	-	-	-	-	-
MLEOMEED_02582	2.66e-28	yxeD	-	-	-	-	-	-	-
MLEOMEED_02583	6.79e-91	-	-	-	-	-	-	-	-
MLEOMEED_02584	9.01e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_02585	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MLEOMEED_02586	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MLEOMEED_02587	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_02588	4e-233	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_02589	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_02590	2.43e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLEOMEED_02591	5.39e-187	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLEOMEED_02592	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MLEOMEED_02593	8.95e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLEOMEED_02594	1.46e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MLEOMEED_02595	4.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLEOMEED_02596	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLEOMEED_02597	2.13e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLEOMEED_02598	1.46e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLEOMEED_02599	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLEOMEED_02600	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MLEOMEED_02601	1.74e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MLEOMEED_02603	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
MLEOMEED_02604	1.77e-314	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_02605	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MLEOMEED_02607	4.33e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_02608	3.66e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MLEOMEED_02609	1.21e-315	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MLEOMEED_02610	6.59e-111	yxbD	3.2.2.20	-	K	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Acetyltransferase (GNAT) domain
MLEOMEED_02611	1.16e-239	-	-	-	S	-	-	-	A domain family that is part of the cupin metalloenzyme superfamily.
MLEOMEED_02612	1.29e-177	yxbB	-	-	Q	-	-	-	Met-10+ like-protein
MLEOMEED_02613	3.65e-59	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
MLEOMEED_02614	8.99e-114	yxnB	-	-	-	-	-	-	-
MLEOMEED_02615	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MLEOMEED_02616	2.1e-270	yxaM	-	-	U	-	-	-	MFS_1 like family
MLEOMEED_02617	2.63e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
MLEOMEED_02618	1.43e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MLEOMEED_02619	2.83e-99	yxaI	-	-	S	-	-	-	membrane protein domain
MLEOMEED_02620	2.88e-290	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MLEOMEED_02621	9.33e-254	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
MLEOMEED_02622	9.61e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MLEOMEED_02623	4.48e-257	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_02624	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_02625	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MLEOMEED_02626	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MLEOMEED_02627	1.79e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MLEOMEED_02628	2.54e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MLEOMEED_02629	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
MLEOMEED_02630	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MLEOMEED_02631	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MLEOMEED_02632	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLEOMEED_02633	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MLEOMEED_02634	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MLEOMEED_02635	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MLEOMEED_02636	6.69e-47	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLEOMEED_02637	6.34e-165	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_02638	1.44e-24	-	-	-	-	-	-	-	-
MLEOMEED_02639	2.65e-54	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MLEOMEED_02640	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLEOMEED_02641	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLEOMEED_02642	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MLEOMEED_02643	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MLEOMEED_02644	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MLEOMEED_02645	8.89e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MLEOMEED_02646	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MLEOMEED_02647	4.19e-239	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_02648	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MLEOMEED_02650	4.49e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MLEOMEED_02651	2.91e-180	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MLEOMEED_02652	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_02653	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MLEOMEED_02654	6.19e-39	ywdA	-	-	-	-	-	-	-
MLEOMEED_02655	5.43e-188	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MLEOMEED_02656	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MLEOMEED_02657	8.74e-146	ywdD	-	-	-	-	-	-	-
MLEOMEED_02659	5.69e-193	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MLEOMEED_02660	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLEOMEED_02661	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MLEOMEED_02662	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MLEOMEED_02663	4.57e-304	ywdJ	-	-	F	-	-	-	Xanthine uracil
MLEOMEED_02664	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
MLEOMEED_02665	7.61e-114	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLEOMEED_02666	4.87e-188	spsA	-	-	M	-	-	-	Spore Coat
MLEOMEED_02667	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MLEOMEED_02668	4.54e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MLEOMEED_02669	1.04e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MLEOMEED_02670	6.8e-272	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MLEOMEED_02671	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MLEOMEED_02672	2.54e-243	spsG	-	-	M	-	-	-	Spore Coat
MLEOMEED_02673	2.6e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLEOMEED_02674	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLEOMEED_02675	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLEOMEED_02676	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MLEOMEED_02677	1.1e-102	-	-	-	-	-	-	-	-
MLEOMEED_02678	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MLEOMEED_02679	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLEOMEED_02680	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MLEOMEED_02681	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MLEOMEED_02682	1.89e-275	ywfA	-	-	EGP	-	-	-	-transporter
MLEOMEED_02683	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLEOMEED_02684	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLEOMEED_02685	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_02686	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLEOMEED_02687	1.36e-268	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MLEOMEED_02688	1.89e-298	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MLEOMEED_02689	3.52e-178	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_02690	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MLEOMEED_02691	7.1e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MLEOMEED_02692	9.56e-212	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_02693	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLEOMEED_02694	1.57e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MLEOMEED_02695	5.65e-147	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MLEOMEED_02696	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MLEOMEED_02697	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MLEOMEED_02698	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MLEOMEED_02699	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02700	2.66e-307	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MLEOMEED_02702	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLEOMEED_02703	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02704	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MLEOMEED_02705	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MLEOMEED_02706	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
MLEOMEED_02707	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MLEOMEED_02708	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLEOMEED_02709	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MLEOMEED_02710	6.61e-110	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MLEOMEED_02712	2.88e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MLEOMEED_02713	2.36e-291	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MLEOMEED_02714	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MLEOMEED_02716	0.0	-	-	-	L	-	-	-	Peptidase, M16
MLEOMEED_02717	7.55e-280	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
MLEOMEED_02718	1.07e-300	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MLEOMEED_02719	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MLEOMEED_02721	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
MLEOMEED_02722	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
MLEOMEED_02723	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
MLEOMEED_02724	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MLEOMEED_02726	1.27e-134	-	-	-	-	-	-	-	-
MLEOMEED_02730	9.38e-229	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MLEOMEED_02731	2.74e-183	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MLEOMEED_02732	2.23e-233	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MLEOMEED_02734	1.38e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MLEOMEED_02735	2.49e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MLEOMEED_02736	1.39e-92	-	-	-	-	-	-	-	-
MLEOMEED_02737	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_02738	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_02740	1.99e-106	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MLEOMEED_02741	1.78e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MLEOMEED_02742	6.61e-278	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLEOMEED_02743	2.77e-219	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLEOMEED_02744	3.26e-50	-	-	-	-	-	-	-	-
MLEOMEED_02745	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MLEOMEED_02746	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MLEOMEED_02747	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLEOMEED_02748	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_02749	8.77e-283	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MLEOMEED_02750	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLEOMEED_02751	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MLEOMEED_02752	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MLEOMEED_02753	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MLEOMEED_02754	3.3e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MLEOMEED_02755	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLEOMEED_02756	3.99e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02757	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MLEOMEED_02758	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLEOMEED_02759	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_02760	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02761	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLEOMEED_02762	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MLEOMEED_02763	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MLEOMEED_02764	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
MLEOMEED_02765	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MLEOMEED_02766	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
MLEOMEED_02767	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MLEOMEED_02768	1.97e-199	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MLEOMEED_02769	4.19e-93	yviE	-	-	-	-	-	-	-
MLEOMEED_02770	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLEOMEED_02771	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLEOMEED_02772	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLEOMEED_02773	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MLEOMEED_02774	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLEOMEED_02775	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MLEOMEED_02776	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MLEOMEED_02777	9.14e-88	-	-	-	-	-	-	-	-
MLEOMEED_02778	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLEOMEED_02779	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLEOMEED_02780	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLEOMEED_02781	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MLEOMEED_02782	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MLEOMEED_02783	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MLEOMEED_02784	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLEOMEED_02785	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MLEOMEED_02786	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MLEOMEED_02787	3.86e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLEOMEED_02788	5.47e-298	yvkA	-	-	P	-	-	-	-transporter
MLEOMEED_02789	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02790	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MLEOMEED_02791	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02792	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLEOMEED_02793	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLEOMEED_02794	2.57e-104	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLEOMEED_02795	2.73e-46	yvkN	-	-	-	-	-	-	-
MLEOMEED_02796	8.09e-65	yvlA	-	-	-	-	-	-	-
MLEOMEED_02797	1.17e-220	yvlB	-	-	S	-	-	-	Putative adhesin
MLEOMEED_02798	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MLEOMEED_02799	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MLEOMEED_02800	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MLEOMEED_02801	6.2e-114	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_02802	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MLEOMEED_02803	1.61e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MLEOMEED_02804	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_02805	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MLEOMEED_02806	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MLEOMEED_02807	1.39e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLEOMEED_02808	2.25e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLEOMEED_02809	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLEOMEED_02810	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLEOMEED_02811	3.19e-212	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MLEOMEED_02812	4.51e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLEOMEED_02813	5.29e-121	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MLEOMEED_02814	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
MLEOMEED_02815	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MLEOMEED_02816	2.07e-282	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLEOMEED_02817	9.09e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLEOMEED_02818	1.19e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLEOMEED_02819	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MLEOMEED_02820	7.21e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLEOMEED_02821	1.44e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLEOMEED_02822	9.74e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLEOMEED_02823	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MLEOMEED_02824	6.36e-172	-	-	-	-	-	-	-	-
MLEOMEED_02825	7.25e-211	-	-	-	-	-	-	-	-
MLEOMEED_02826	2.26e-226	-	-	-	-	-	-	-	-
MLEOMEED_02828	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MLEOMEED_02829	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MLEOMEED_02830	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MLEOMEED_02831	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MLEOMEED_02832	3.23e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MLEOMEED_02833	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MLEOMEED_02834	4.26e-230	ykvI	-	-	S	-	-	-	membrane
MLEOMEED_02835	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLEOMEED_02836	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MLEOMEED_02837	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLEOMEED_02838	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLEOMEED_02839	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02840	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_02841	2.69e-275	-	-	-	M	-	-	-	Glycosyl transferases group 1
MLEOMEED_02842	1.85e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
MLEOMEED_02843	2.5e-169	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MLEOMEED_02844	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MLEOMEED_02845	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02846	2.6e-39	-	-	-	-	-	-	-	-
MLEOMEED_02847	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MLEOMEED_02848	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_02849	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
MLEOMEED_02850	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MLEOMEED_02851	3.99e-09	-	-	-	-	-	-	-	-
MLEOMEED_02852	7.85e-266	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MLEOMEED_02854	3.28e-230	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02856	3.41e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MLEOMEED_02857	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_02858	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MLEOMEED_02859	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLEOMEED_02860	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_02861	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MLEOMEED_02862	5.49e-170	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_02863	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_02864	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLEOMEED_02865	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MLEOMEED_02866	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MLEOMEED_02867	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_02868	5.32e-286	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MLEOMEED_02869	1.05e-22	-	-	-	-	-	-	-	-
MLEOMEED_02870	4.24e-217	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MLEOMEED_02871	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
MLEOMEED_02872	8.89e-306	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_02873	7.1e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02874	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MLEOMEED_02875	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_02876	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
MLEOMEED_02877	1.52e-120	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
MLEOMEED_02879	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MLEOMEED_02880	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_02881	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MLEOMEED_02882	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MLEOMEED_02883	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
MLEOMEED_02884	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02885	7.72e-114	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
MLEOMEED_02886	1.33e-226	ykuO	-	-	-	-	-	-	-
MLEOMEED_02887	1.3e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MLEOMEED_02888	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLEOMEED_02889	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLEOMEED_02890	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MLEOMEED_02891	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MLEOMEED_02892	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MLEOMEED_02893	6.25e-106	ykuV	-	-	CO	-	-	-	thiol-disulfide
MLEOMEED_02894	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
MLEOMEED_02895	1.47e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
MLEOMEED_02896	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLEOMEED_02897	6.5e-246	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLEOMEED_02898	1.05e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MLEOMEED_02899	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MLEOMEED_02900	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MLEOMEED_02901	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLEOMEED_02902	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MLEOMEED_02903	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MLEOMEED_02904	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
MLEOMEED_02905	4.93e-235	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLEOMEED_02906	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_02907	2.1e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MLEOMEED_02908	1.61e-102	yybN	-	-	S	-	-	-	Protein of unknown function (DUF2712)
MLEOMEED_02909	3.44e-22	-	-	-	-	-	-	-	-
MLEOMEED_02910	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MLEOMEED_02911	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MLEOMEED_02912	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MLEOMEED_02913	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLEOMEED_02914	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MLEOMEED_02915	3.97e-145	yneB	-	-	L	-	-	-	resolvase
MLEOMEED_02916	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLEOMEED_02917	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLEOMEED_02919	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLEOMEED_02920	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MLEOMEED_02921	1.68e-177	yndL	-	-	S	-	-	-	Replication protein
MLEOMEED_02923	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MLEOMEED_02924	1.26e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MLEOMEED_02925	9.15e-199	yndG	-	-	S	-	-	-	DoxX-like family
MLEOMEED_02926	9.64e-290	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MLEOMEED_02927	2.38e-251	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
MLEOMEED_02928	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MLEOMEED_02931	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MLEOMEED_02932	8.92e-96	-	-	-	-	-	-	-	-
MLEOMEED_02933	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
MLEOMEED_02934	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLEOMEED_02935	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MLEOMEED_02936	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MLEOMEED_02937	1.05e-222	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MLEOMEED_02938	2.56e-141	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MLEOMEED_02939	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
MLEOMEED_02940	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MLEOMEED_02941	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLEOMEED_02944	5.95e-101	yckC	-	-	S	-	-	-	membrane
MLEOMEED_02945	3.53e-69	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MLEOMEED_02946	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MLEOMEED_02947	7.06e-93	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MLEOMEED_02948	4.78e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MLEOMEED_02949	6.52e-269	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MLEOMEED_02950	1.38e-127	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MLEOMEED_02951	2.39e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MLEOMEED_02952	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
MLEOMEED_02953	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_02954	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_02955	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLEOMEED_02956	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MLEOMEED_02957	1.38e-291	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MLEOMEED_02958	1.61e-126	-	-	-	S	-	-	-	YcxB-like protein
MLEOMEED_02959	1.77e-209	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_02960	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MLEOMEED_02961	1.37e-144	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MLEOMEED_02962	3.04e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MLEOMEED_02963	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MLEOMEED_02964	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MLEOMEED_02965	1.5e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MLEOMEED_02966	9.2e-210	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MLEOMEED_02967	2.33e-142	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLEOMEED_02968	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLEOMEED_02969	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MLEOMEED_02970	3.05e-109	yclD	-	-	-	-	-	-	-
MLEOMEED_02971	5.12e-207	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MLEOMEED_02972	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MLEOMEED_02973	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MLEOMEED_02975	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MLEOMEED_02976	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MLEOMEED_02977	2.29e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MLEOMEED_02978	2.05e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MLEOMEED_02979	5.59e-280	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MLEOMEED_02980	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_02981	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MLEOMEED_02982	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MLEOMEED_02984	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MLEOMEED_02985	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MLEOMEED_02986	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MLEOMEED_02987	5.42e-206	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_02988	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_02989	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_02990	4.98e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MLEOMEED_02991	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MLEOMEED_02992	1.76e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_02993	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MLEOMEED_02994	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MLEOMEED_02995	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MLEOMEED_02996	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_02997	2.4e-313	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLEOMEED_02998	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLEOMEED_02999	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MLEOMEED_03000	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_03001	1.07e-138	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03002	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MLEOMEED_03003	5.18e-139	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MLEOMEED_03004	1.34e-74	-	-	-	-	-	-	-	-
MLEOMEED_03005	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLEOMEED_03006	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLEOMEED_03007	3.77e-269	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLEOMEED_03008	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MLEOMEED_03010	6.21e-97	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MLEOMEED_03011	2.64e-147	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
MLEOMEED_03012	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MLEOMEED_03014	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MLEOMEED_03015	9.39e-182	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MLEOMEED_03016	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLEOMEED_03017	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MLEOMEED_03018	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MLEOMEED_03019	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MLEOMEED_03020	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03021	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MLEOMEED_03023	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
MLEOMEED_03024	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MLEOMEED_03025	3.26e-224	ycsN	-	-	S	-	-	-	Oxidoreductase
MLEOMEED_03026	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MLEOMEED_03027	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MLEOMEED_03028	6.05e-129	ydaC	-	-	Q	-	-	-	Methyltransferase domain
MLEOMEED_03029	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_03030	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MLEOMEED_03031	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLEOMEED_03032	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
MLEOMEED_03033	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLEOMEED_03034	1.88e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MLEOMEED_03035	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MLEOMEED_03036	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLEOMEED_03037	3.08e-267	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLEOMEED_03038	1.14e-195	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MLEOMEED_03039	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MLEOMEED_03040	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MLEOMEED_03041	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MLEOMEED_03042	0.0	ydaO	-	-	E	-	-	-	amino acid
MLEOMEED_03043	3.75e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MLEOMEED_03044	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MLEOMEED_03045	2.14e-53	-	-	-	-	-	-	-	-
MLEOMEED_03046	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MLEOMEED_03047	1.67e-42	ydaS	-	-	S	-	-	-	membrane
MLEOMEED_03048	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MLEOMEED_03049	1.06e-190	ydbA	-	-	P	-	-	-	EcsC protein family
MLEOMEED_03050	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MLEOMEED_03051	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
MLEOMEED_03052	5.41e-84	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MLEOMEED_03053	1.35e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MLEOMEED_03054	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLEOMEED_03055	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MLEOMEED_03056	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MLEOMEED_03057	4.43e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLEOMEED_03058	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
MLEOMEED_03059	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03060	7.34e-160	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLEOMEED_03061	9.32e-70	ydbL	-	-	-	-	-	-	-
MLEOMEED_03062	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MLEOMEED_03063	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
MLEOMEED_03065	1.91e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLEOMEED_03066	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
MLEOMEED_03067	3.07e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MLEOMEED_03068	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLEOMEED_03069	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLEOMEED_03070	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MLEOMEED_03071	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MLEOMEED_03072	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MLEOMEED_03073	1.95e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLEOMEED_03074	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MLEOMEED_03075	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLEOMEED_03076	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLEOMEED_03077	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MLEOMEED_03078	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MLEOMEED_03079	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MLEOMEED_03080	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLEOMEED_03081	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MLEOMEED_03082	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MLEOMEED_03083	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLEOMEED_03084	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_03085	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MLEOMEED_03089	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
MLEOMEED_03090	1.54e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_03091	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MLEOMEED_03092	1.93e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MLEOMEED_03100	4.41e-270	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MLEOMEED_03101	1.41e-119	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MLEOMEED_03102	1.91e-81	-	-	-	K	-	-	-	Transcriptional
MLEOMEED_03103	8.96e-24	-	-	-	-	-	-	-	-
MLEOMEED_03104	9.52e-56	-	-	-	-	-	-	-	-
MLEOMEED_03106	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MLEOMEED_03107	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
MLEOMEED_03108	2.62e-263	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
MLEOMEED_03111	1.38e-43	yddA	-	-	-	-	-	-	-
MLEOMEED_03112	7.65e-232	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
MLEOMEED_03113	3.41e-54	yddC	-	-	-	-	-	-	-
MLEOMEED_03114	7.8e-124	yddD	-	-	S	-	-	-	TcpE family
MLEOMEED_03115	0.0	yddE	-	-	S	-	-	-	AAA-like domain
MLEOMEED_03116	2.81e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
MLEOMEED_03117	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
MLEOMEED_03118	4.74e-243	yddH	-	-	M	-	-	-	Lysozyme-like
MLEOMEED_03119	4.05e-114	yddI	-	-	-	-	-	-	-
MLEOMEED_03120	6.67e-86	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MLEOMEED_03121	3.36e-87	-	-	-	S	-	-	-	TIR domain
MLEOMEED_03122	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLEOMEED_03123	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MLEOMEED_03124	5.68e-83	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLEOMEED_03125	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MLEOMEED_03126	9.38e-95	ytwI	-	-	S	-	-	-	membrane
MLEOMEED_03127	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MLEOMEED_03128	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MLEOMEED_03129	2.55e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MLEOMEED_03130	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_03131	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MLEOMEED_03132	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLEOMEED_03133	7e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLEOMEED_03134	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MLEOMEED_03135	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLEOMEED_03136	4.54e-205	ytbE	-	-	S	-	-	-	reductase
MLEOMEED_03137	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MLEOMEED_03138	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03139	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLEOMEED_03140	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLEOMEED_03141	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLEOMEED_03142	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MLEOMEED_03143	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MLEOMEED_03144	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MLEOMEED_03145	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
MLEOMEED_03146	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLEOMEED_03147	2.07e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MLEOMEED_03148	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_03149	2.9e-168	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MLEOMEED_03150	2.08e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLEOMEED_03151	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLEOMEED_03153	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLEOMEED_03154	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MLEOMEED_03155	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLEOMEED_03156	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
MLEOMEED_03157	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MLEOMEED_03158	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MLEOMEED_03159	4.21e-243	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MLEOMEED_03160	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MLEOMEED_03161	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MLEOMEED_03162	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLEOMEED_03163	1.05e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MLEOMEED_03164	1.47e-288	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLEOMEED_03165	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MLEOMEED_03166	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MLEOMEED_03167	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MLEOMEED_03168	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MLEOMEED_03169	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MLEOMEED_03171	8.17e-52	ysfE	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MLEOMEED_03172	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MLEOMEED_03173	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MLEOMEED_03174	6.71e-265	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MLEOMEED_03175	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MLEOMEED_03176	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLEOMEED_03177	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLEOMEED_03178	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLEOMEED_03179	6.77e-219	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLEOMEED_03180	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLEOMEED_03181	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MLEOMEED_03182	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MLEOMEED_03183	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLEOMEED_03184	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MLEOMEED_03185	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLEOMEED_03186	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03187	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MLEOMEED_03188	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MLEOMEED_03189	1.23e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MLEOMEED_03191	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MLEOMEED_03192	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MLEOMEED_03193	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLEOMEED_03194	4.83e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MLEOMEED_03195	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MLEOMEED_03196	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MLEOMEED_03197	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MLEOMEED_03198	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MLEOMEED_03199	1.79e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MLEOMEED_03200	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03201	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_03202	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MLEOMEED_03203	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MLEOMEED_03204	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLEOMEED_03205	1.06e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLEOMEED_03206	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MLEOMEED_03208	1.01e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03209	3.32e-107	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MLEOMEED_03211	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MLEOMEED_03212	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MLEOMEED_03213	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLEOMEED_03214	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLEOMEED_03215	1.06e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLEOMEED_03216	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLEOMEED_03217	5.35e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLEOMEED_03218	2.73e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MLEOMEED_03219	8.87e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLEOMEED_03220	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLEOMEED_03221	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MLEOMEED_03222	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLEOMEED_03223	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MLEOMEED_03224	3.73e-11	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
MLEOMEED_03225	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MLEOMEED_03226	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLEOMEED_03227	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_03228	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLEOMEED_03229	3.84e-189	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLEOMEED_03230	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MLEOMEED_03231	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
MLEOMEED_03232	5.53e-205	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MLEOMEED_03233	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLEOMEED_03234	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLEOMEED_03235	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MLEOMEED_03236	3.67e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MLEOMEED_03237	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MLEOMEED_03238	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLEOMEED_03239	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MLEOMEED_03240	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLEOMEED_03241	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MLEOMEED_03242	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLEOMEED_03243	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MLEOMEED_03244	4.4e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MLEOMEED_03245	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLEOMEED_03246	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MLEOMEED_03247	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MLEOMEED_03248	3.84e-185	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLEOMEED_03249	1.33e-224	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLEOMEED_03250	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLEOMEED_03251	3.8e-150	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLEOMEED_03253	3.58e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MLEOMEED_03254	7.32e-230	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MLEOMEED_03255	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MLEOMEED_03256	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MLEOMEED_03257	1.24e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MLEOMEED_03258	4.33e-189	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MLEOMEED_03259	2.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MLEOMEED_03260	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MLEOMEED_03261	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MLEOMEED_03262	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
MLEOMEED_03263	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MLEOMEED_03264	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MLEOMEED_03265	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLEOMEED_03266	4.59e-289	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLEOMEED_03267	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLEOMEED_03268	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLEOMEED_03269	2.21e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLEOMEED_03270	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLEOMEED_03271	3.73e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLEOMEED_03272	3.03e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MLEOMEED_03273	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MLEOMEED_03274	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLEOMEED_03275	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MLEOMEED_03276	2.83e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MLEOMEED_03277	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MLEOMEED_03278	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03279	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MLEOMEED_03280	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MLEOMEED_03281	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MLEOMEED_03282	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLEOMEED_03283	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLEOMEED_03284	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLEOMEED_03285	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MLEOMEED_03286	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MLEOMEED_03287	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLEOMEED_03288	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLEOMEED_03289	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MLEOMEED_03290	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLEOMEED_03291	1.67e-114	-	-	-	-	-	-	-	-
MLEOMEED_03292	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLEOMEED_03293	9.7e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLEOMEED_03294	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MLEOMEED_03295	2.95e-50	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MLEOMEED_03296	5.89e-81	ylqD	-	-	S	-	-	-	YlqD protein
MLEOMEED_03297	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLEOMEED_03298	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MLEOMEED_03299	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLEOMEED_03300	1.2e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLEOMEED_03301	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLEOMEED_03302	0.0	ylqG	-	-	-	-	-	-	-
MLEOMEED_03303	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MLEOMEED_03304	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLEOMEED_03305	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLEOMEED_03306	6.53e-218	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MLEOMEED_03307	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLEOMEED_03308	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLEOMEED_03309	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MLEOMEED_03310	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLEOMEED_03311	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLEOMEED_03312	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLEOMEED_03314	1.99e-17	-	-	-	-	-	-	-	-
MLEOMEED_03315	1.43e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_03316	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MLEOMEED_03317	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MLEOMEED_03318	3.83e-229	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MLEOMEED_03319	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLEOMEED_03320	1.42e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MLEOMEED_03321	2.07e-169	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MLEOMEED_03322	4.9e-263	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MLEOMEED_03323	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
MLEOMEED_03324	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MLEOMEED_03325	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MLEOMEED_03326	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MLEOMEED_03327	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLEOMEED_03328	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLEOMEED_03329	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLEOMEED_03330	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MLEOMEED_03331	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLEOMEED_03332	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MLEOMEED_03333	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLEOMEED_03334	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLEOMEED_03335	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLEOMEED_03336	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLEOMEED_03337	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MLEOMEED_03340	1.36e-08	-	-	-	-	-	-	-	-
MLEOMEED_03341	6.85e-229	-	-	-	-	-	-	-	-
MLEOMEED_03342	1.92e-162	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MLEOMEED_03343	1.21e-90	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MLEOMEED_03344	4.35e-194	-	-	-	-	-	-	-	-
MLEOMEED_03345	3.02e-88	-	-	-	S	-	-	-	SnoaL-like domain
MLEOMEED_03346	1.46e-164	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MLEOMEED_03347	3.31e-281	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_03348	1.36e-212	yybE	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03349	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_03350	1.27e-99	yybC	-	-	-	-	-	-	-
MLEOMEED_03351	5.29e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MLEOMEED_03352	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
MLEOMEED_03353	2.45e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_03354	8.73e-132	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MLEOMEED_03355	4.03e-130	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MLEOMEED_03356	1.09e-87	-	-	-	S	-	-	-	YjbR
MLEOMEED_03357	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
MLEOMEED_03358	7.32e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
MLEOMEED_03359	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MLEOMEED_03360	7.53e-283	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MLEOMEED_03361	1.33e-134	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MLEOMEED_03362	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MLEOMEED_03363	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
MLEOMEED_03364	1.21e-170	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MLEOMEED_03365	1.11e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MLEOMEED_03366	2.1e-272	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MLEOMEED_03367	2.04e-129	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MLEOMEED_03368	2.38e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MLEOMEED_03369	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03370	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLEOMEED_03371	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MLEOMEED_03372	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MLEOMEED_03373	8.9e-247	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MLEOMEED_03374	4.74e-209	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MLEOMEED_03375	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
MLEOMEED_03376	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
MLEOMEED_03377	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MLEOMEED_03378	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLEOMEED_03379	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLEOMEED_03380	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MLEOMEED_03381	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MLEOMEED_03382	1.15e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MLEOMEED_03383	2.05e-230	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
MLEOMEED_03384	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MLEOMEED_03385	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLEOMEED_03386	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
MLEOMEED_03387	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLEOMEED_03388	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MLEOMEED_03389	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_03390	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MLEOMEED_03391	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MLEOMEED_03392	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_03393	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MLEOMEED_03394	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MLEOMEED_03395	2.06e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MLEOMEED_03396	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MLEOMEED_03397	1.25e-127	ycgB	-	-	-	-	-	-	-
MLEOMEED_03398	0.0	ycgA	-	-	S	-	-	-	Membrane
MLEOMEED_03399	2.5e-279	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MLEOMEED_03400	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MLEOMEED_03401	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MLEOMEED_03402	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MLEOMEED_03403	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MLEOMEED_03404	1.17e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MLEOMEED_03405	2.32e-279	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MLEOMEED_03406	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
MLEOMEED_03407	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MLEOMEED_03408	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MLEOMEED_03409	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MLEOMEED_03410	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MLEOMEED_03411	2.64e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MLEOMEED_03412	9.18e-242	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_03413	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLEOMEED_03414	1.99e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLEOMEED_03415	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MLEOMEED_03416	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MLEOMEED_03417	5.87e-181	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_03418	1.42e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MLEOMEED_03419	3.91e-125	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MLEOMEED_03420	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_03421	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_03422	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MLEOMEED_03423	5.83e-223	yccK	-	-	C	-	-	-	Aldo keto reductase
MLEOMEED_03424	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MLEOMEED_03425	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MLEOMEED_03426	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MLEOMEED_03427	9.56e-217	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MLEOMEED_03428	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MLEOMEED_03429	4.32e-78	-	-	-	S	-	-	-	RDD family
MLEOMEED_03430	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLEOMEED_03431	8.74e-260	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLEOMEED_03432	6.54e-132	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MLEOMEED_03433	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MLEOMEED_03434	3.48e-268	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MLEOMEED_03435	2.52e-156	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLEOMEED_03436	7.6e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLEOMEED_03437	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLEOMEED_03438	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MLEOMEED_03439	4.66e-175	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
MLEOMEED_03440	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MLEOMEED_03441	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MLEOMEED_03442	4.25e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
MLEOMEED_03443	1.66e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03444	1.66e-218	ycbM	-	-	T	-	-	-	Histidine kinase
MLEOMEED_03445	6.64e-162	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_03446	1.87e-220	eamA1	-	-	EG	-	-	-	spore germination
MLEOMEED_03447	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MLEOMEED_03449	7.17e-147	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MLEOMEED_03450	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MLEOMEED_03451	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MLEOMEED_03452	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MLEOMEED_03453	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_03454	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLEOMEED_03455	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MLEOMEED_03456	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MLEOMEED_03457	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_03458	9.16e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MLEOMEED_03459	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MLEOMEED_03460	2.23e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MLEOMEED_03461	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MLEOMEED_03462	9.84e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MLEOMEED_03464	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MLEOMEED_03465	7.72e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLEOMEED_03466	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_03467	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLEOMEED_03468	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MLEOMEED_03469	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03470	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
MLEOMEED_03471	2.33e-61	ybfN	-	-	-	-	-	-	-
MLEOMEED_03472	4.33e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLEOMEED_03473	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MLEOMEED_03474	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLEOMEED_03475	2.02e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MLEOMEED_03477	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MLEOMEED_03478	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLEOMEED_03479	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MLEOMEED_03480	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_03481	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MLEOMEED_03482	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLEOMEED_03483	2.29e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLEOMEED_03484	4.18e-141	yfiR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03485	4.51e-281	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
MLEOMEED_03486	2.41e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MLEOMEED_03487	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MLEOMEED_03488	5.39e-106	yfiV	-	-	K	-	-	-	transcriptional
MLEOMEED_03489	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLEOMEED_03490	2.81e-233	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MLEOMEED_03491	1.54e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_03492	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_03493	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
MLEOMEED_03494	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
MLEOMEED_03495	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
MLEOMEED_03497	1.13e-221	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MLEOMEED_03498	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MLEOMEED_03499	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MLEOMEED_03501	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
MLEOMEED_03502	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
MLEOMEED_03503	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
MLEOMEED_03504	3.58e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MLEOMEED_03505	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MLEOMEED_03506	3.37e-219	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MLEOMEED_03507	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MLEOMEED_03508	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MLEOMEED_03509	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MLEOMEED_03510	8.47e-268	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MLEOMEED_03511	1.73e-48	yfhS	-	-	-	-	-	-	-
MLEOMEED_03512	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_03513	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MLEOMEED_03514	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MLEOMEED_03515	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MLEOMEED_03516	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MLEOMEED_03517	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
MLEOMEED_03518	1.19e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MLEOMEED_03519	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MLEOMEED_03520	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MLEOMEED_03521	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MLEOMEED_03522	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MLEOMEED_03523	7.21e-30	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MLEOMEED_03524	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MLEOMEED_03525	3.8e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MLEOMEED_03526	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MLEOMEED_03527	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MLEOMEED_03528	3.95e-59	yhcC	-	-	-	-	-	-	-
MLEOMEED_03529	2.92e-69	-	-	-	-	-	-	-	-
MLEOMEED_03530	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03531	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03532	6.47e-213	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03533	3.45e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLEOMEED_03534	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MLEOMEED_03535	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MLEOMEED_03536	2.47e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MLEOMEED_03537	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLEOMEED_03538	3.23e-80	yhcM	-	-	-	-	-	-	-
MLEOMEED_03539	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLEOMEED_03540	3.96e-227	yhcP	-	-	-	-	-	-	-
MLEOMEED_03541	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
MLEOMEED_03542	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MLEOMEED_03543	3.9e-138	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MLEOMEED_03544	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MLEOMEED_03545	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MLEOMEED_03546	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MLEOMEED_03547	3.04e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MLEOMEED_03548	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLEOMEED_03549	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLEOMEED_03550	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLEOMEED_03551	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MLEOMEED_03552	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLEOMEED_03553	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLEOMEED_03554	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MLEOMEED_03555	2.29e-273	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_03556	5.68e-148	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_03557	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MLEOMEED_03558	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MLEOMEED_03559	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MLEOMEED_03560	2.4e-275	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MLEOMEED_03561	1.37e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MLEOMEED_03562	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
MLEOMEED_03563	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MLEOMEED_03564	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MLEOMEED_03565	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MLEOMEED_03566	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03567	5.51e-263	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MLEOMEED_03568	1.41e-208	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_03569	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MLEOMEED_03570	4.29e-310	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLEOMEED_03571	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_03572	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLEOMEED_03573	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MLEOMEED_03574	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MLEOMEED_03575	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_03576	6.74e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
MLEOMEED_03577	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLEOMEED_03578	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MLEOMEED_03579	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MLEOMEED_03580	4.37e-285	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MLEOMEED_03581	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MLEOMEED_03582	2.69e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLEOMEED_03583	1.01e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLEOMEED_03584	5.44e-174	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MLEOMEED_03585	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MLEOMEED_03586	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MLEOMEED_03587	2.93e-180	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLEOMEED_03588	5.7e-200	nodB1	-	-	G	-	-	-	deacetylase
MLEOMEED_03589	2.23e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLEOMEED_03590	3.94e-307	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MLEOMEED_03591	1.86e-109	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
MLEOMEED_03592	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MLEOMEED_03593	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MLEOMEED_03594	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MLEOMEED_03595	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MLEOMEED_03596	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MLEOMEED_03597	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MLEOMEED_03598	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MLEOMEED_03599	1.51e-261	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MLEOMEED_03600	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MLEOMEED_03601	6.69e-264	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MLEOMEED_03602	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MLEOMEED_03603	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MLEOMEED_03604	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MLEOMEED_03605	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MLEOMEED_03607	1.6e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MLEOMEED_03608	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
MLEOMEED_03609	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03610	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MLEOMEED_03611	9.85e-303	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MLEOMEED_03612	0.0	yhaN	-	-	L	-	-	-	AAA domain
MLEOMEED_03613	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MLEOMEED_03614	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MLEOMEED_03615	2.29e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLEOMEED_03616	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MLEOMEED_03617	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MLEOMEED_03618	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MLEOMEED_03619	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MLEOMEED_03620	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MLEOMEED_03621	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLEOMEED_03622	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLEOMEED_03623	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MLEOMEED_03624	3.11e-272	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MLEOMEED_03625	5e-162	ecsC	-	-	S	-	-	-	EcsC protein family
MLEOMEED_03626	4.8e-295	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLEOMEED_03627	8.98e-317	yhfA	-	-	C	-	-	-	membrane
MLEOMEED_03628	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
MLEOMEED_03629	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MLEOMEED_03630	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MLEOMEED_03631	7.78e-261	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLEOMEED_03632	2.06e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MLEOMEED_03633	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLEOMEED_03634	3.49e-133	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03635	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MLEOMEED_03636	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLEOMEED_03637	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
MLEOMEED_03638	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
MLEOMEED_03639	3.75e-94	-	-	-	S	-	-	-	ASCH
MLEOMEED_03640	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLEOMEED_03641	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLEOMEED_03642	1.21e-246	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MLEOMEED_03643	1.82e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
MLEOMEED_03644	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MLEOMEED_03645	2.78e-85	yhfM	-	-	-	-	-	-	-
MLEOMEED_03646	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
MLEOMEED_03647	2.94e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MLEOMEED_03648	2.75e-105	-	-	-	K	-	-	-	acetyltransferase
MLEOMEED_03649	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MLEOMEED_03650	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MLEOMEED_03651	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MLEOMEED_03652	1.19e-256	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MLEOMEED_03653	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MLEOMEED_03654	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MLEOMEED_03655	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MLEOMEED_03656	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MLEOMEED_03657	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLEOMEED_03658	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
MLEOMEED_03659	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MLEOMEED_03660	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MLEOMEED_03661	5e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MLEOMEED_03662	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLEOMEED_03663	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MLEOMEED_03664	2.57e-78	yhjD	-	-	-	-	-	-	-
MLEOMEED_03665	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MLEOMEED_03666	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MLEOMEED_03667	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MLEOMEED_03668	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_03669	3.12e-273	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MLEOMEED_03670	3.98e-257	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MLEOMEED_03671	2.63e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
MLEOMEED_03672	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MLEOMEED_03673	1.07e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03674	2.14e-260	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MLEOMEED_03675	1.27e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MLEOMEED_03676	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MLEOMEED_03677	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
MLEOMEED_03678	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
MLEOMEED_03679	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MLEOMEED_03680	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MLEOMEED_03681	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLEOMEED_03682	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MLEOMEED_03683	1.34e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MLEOMEED_03684	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MLEOMEED_03685	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MLEOMEED_03686	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MLEOMEED_03687	8.23e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MLEOMEED_03688	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MLEOMEED_03689	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MLEOMEED_03690	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MLEOMEED_03691	3.96e-224	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MLEOMEED_03692	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLEOMEED_03693	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
MLEOMEED_03694	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MLEOMEED_03695	7.48e-137	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MLEOMEED_03696	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MLEOMEED_03697	1.85e-115	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MLEOMEED_03698	6.82e-193	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MLEOMEED_03699	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
MLEOMEED_03700	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03701	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MLEOMEED_03702	9.72e-254	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MLEOMEED_03703	7.28e-122	yisT	-	-	S	-	-	-	DinB family
MLEOMEED_03704	5.42e-140	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MLEOMEED_03705	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_03706	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MLEOMEED_03707	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLEOMEED_03708	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MLEOMEED_03709	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MLEOMEED_03710	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MLEOMEED_03711	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
MLEOMEED_03712	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
MLEOMEED_03713	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLEOMEED_03714	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MLEOMEED_03715	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MLEOMEED_03716	7.86e-207	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_03717	3.34e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_03718	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLEOMEED_03719	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MLEOMEED_03720	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MLEOMEED_03721	4.16e-122	-	-	-	-	-	-	-	-
MLEOMEED_03722	1.42e-218	-	-	-	-	-	-	-	-
MLEOMEED_03723	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MLEOMEED_03724	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MLEOMEED_03725	7.76e-123	-	-	-	-	-	-	-	-
MLEOMEED_03726	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MLEOMEED_03727	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MLEOMEED_03728	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03729	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MLEOMEED_03730	1.61e-92	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MLEOMEED_03731	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MLEOMEED_03732	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MLEOMEED_03733	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MLEOMEED_03734	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MLEOMEED_03735	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
MLEOMEED_03736	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MLEOMEED_03737	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MLEOMEED_03738	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLEOMEED_03739	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLEOMEED_03740	5.06e-144	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_03741	1.34e-37	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MLEOMEED_03742	1.12e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MLEOMEED_03743	1.02e-196	cotB	-	-	-	ko:K06325	-	ko00000	-
MLEOMEED_03744	9.09e-164	ywrJ	-	-	-	-	-	-	-
MLEOMEED_03745	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLEOMEED_03746	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
MLEOMEED_03747	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MLEOMEED_03748	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MLEOMEED_03749	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MLEOMEED_03750	9.2e-64	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
MLEOMEED_03751	2.49e-122	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MLEOMEED_03752	1.34e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MLEOMEED_03753	2.87e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MLEOMEED_03754	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLEOMEED_03755	5.6e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLEOMEED_03756	6.44e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLEOMEED_03757	2.3e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MLEOMEED_03758	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLEOMEED_03759	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MLEOMEED_03760	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLEOMEED_03761	2.29e-29	ywtC	-	-	-	-	-	-	-
MLEOMEED_03762	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLEOMEED_03763	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MLEOMEED_03764	1.48e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03765	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_03766	2.29e-275	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MLEOMEED_03767	1.24e-256	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MLEOMEED_03768	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MLEOMEED_03769	1.16e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MLEOMEED_03770	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLEOMEED_03771	0.0	-	-	-	-	-	-	-	-
MLEOMEED_03772	3.8e-273	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLEOMEED_03773	1.9e-185	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLEOMEED_03795	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLEOMEED_03796	2.96e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLEOMEED_03797	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
MLEOMEED_03798	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLEOMEED_03799	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLEOMEED_03800	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MLEOMEED_03801	9.43e-263	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
MLEOMEED_03802	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
MLEOMEED_03803	1.7e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
MLEOMEED_03805	3.7e-300	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
MLEOMEED_03806	7.74e-231	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
MLEOMEED_03807	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLEOMEED_03808	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MLEOMEED_03809	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MLEOMEED_03810	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MLEOMEED_03811	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLEOMEED_03812	1.46e-198	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLEOMEED_03813	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLEOMEED_03814	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLEOMEED_03815	1.22e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLEOMEED_03816	1.13e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MLEOMEED_03817	1.83e-180	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLEOMEED_03818	1.64e-299	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLEOMEED_03819	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MLEOMEED_03820	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MLEOMEED_03821	2.96e-241	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLEOMEED_03822	2.81e-316	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MLEOMEED_03823	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MLEOMEED_03824	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MLEOMEED_03825	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLEOMEED_03826	8.26e-96	ytkA	-	-	S	-	-	-	YtkA-like
MLEOMEED_03828	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MLEOMEED_03829	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MLEOMEED_03830	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MLEOMEED_03831	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLEOMEED_03832	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MLEOMEED_03833	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLEOMEED_03834	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLEOMEED_03835	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MLEOMEED_03836	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLEOMEED_03837	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLEOMEED_03838	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MLEOMEED_03839	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_03840	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLEOMEED_03841	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MLEOMEED_03842	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MLEOMEED_03843	6.76e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MLEOMEED_03844	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MLEOMEED_03845	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MLEOMEED_03847	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MLEOMEED_03848	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03849	3.35e-222	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MLEOMEED_03850	1.07e-189	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MLEOMEED_03851	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03852	5.92e-298	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MLEOMEED_03853	1.77e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_03854	1.58e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MLEOMEED_03855	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03856	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MLEOMEED_03857	2.02e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MLEOMEED_03858	2.98e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MLEOMEED_03859	6.61e-184	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLEOMEED_03860	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MLEOMEED_03861	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MLEOMEED_03862	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MLEOMEED_03863	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MLEOMEED_03864	1.32e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MLEOMEED_03865	2.86e-215	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MLEOMEED_03866	4.68e-315	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MLEOMEED_03867	1.12e-244	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03869	1.95e-296	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MLEOMEED_03871	9.48e-188	yoaP	-	-	K	-	-	-	YoaP-like
MLEOMEED_03872	7.38e-88	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MLEOMEED_03873	2.36e-116	-	-	-	-	-	-	-	-
MLEOMEED_03874	3.63e-218	yoaR	-	-	V	-	-	-	vancomycin resistance protein
MLEOMEED_03875	1.6e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MLEOMEED_03876	7.38e-50	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03877	6.92e-192	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
MLEOMEED_03878	6.67e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
MLEOMEED_03879	3.05e-190	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MLEOMEED_03880	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLEOMEED_03881	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLEOMEED_03882	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MLEOMEED_03883	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MLEOMEED_03884	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MLEOMEED_03885	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MLEOMEED_03886	5.24e-188	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MLEOMEED_03887	1.37e-45	-	-	-	-	-	-	-	-
MLEOMEED_03888	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLEOMEED_03889	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MLEOMEED_03890	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MLEOMEED_03891	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MLEOMEED_03892	1.4e-235	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLEOMEED_03893	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MLEOMEED_03894	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MLEOMEED_03895	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MLEOMEED_03896	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MLEOMEED_03897	2.28e-223	yvdE	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03898	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MLEOMEED_03899	1.03e-302	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MLEOMEED_03900	2.12e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MLEOMEED_03901	1.18e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MLEOMEED_03902	2.42e-203	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MLEOMEED_03903	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MLEOMEED_03904	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MLEOMEED_03905	1.01e-156	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MLEOMEED_03906	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLEOMEED_03908	1.99e-235	-	-	-	S	-	-	-	Patatin-like phospholipase
MLEOMEED_03909	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MLEOMEED_03910	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MLEOMEED_03911	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MLEOMEED_03912	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MLEOMEED_03913	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03914	0.0	ybeC	-	-	E	-	-	-	amino acid
MLEOMEED_03915	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MLEOMEED_03916	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MLEOMEED_03917	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MLEOMEED_03918	1.51e-163	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MLEOMEED_03919	5.1e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MLEOMEED_03920	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MLEOMEED_03922	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MLEOMEED_03923	2.15e-99	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MLEOMEED_03924	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MLEOMEED_03925	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MLEOMEED_03926	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MLEOMEED_03927	2.95e-286	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MLEOMEED_03928	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MLEOMEED_03929	7.49e-280	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MLEOMEED_03930	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MLEOMEED_03931	6.3e-251	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MLEOMEED_03932	5.09e-264	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MLEOMEED_03933	4.44e-251	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MLEOMEED_03934	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLEOMEED_03935	1.65e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLEOMEED_03936	6.53e-81	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MLEOMEED_03937	1.2e-284	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MLEOMEED_03938	1.85e-241	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MLEOMEED_03939	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
MLEOMEED_03940	2.57e-308	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLEOMEED_03941	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MLEOMEED_03942	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MLEOMEED_03943	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_03944	2.05e-295	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MLEOMEED_03945	1.3e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MLEOMEED_03946	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MLEOMEED_03947	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MLEOMEED_03948	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MLEOMEED_03949	1.52e-265	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
MLEOMEED_03950	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
MLEOMEED_03951	1.03e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MLEOMEED_03952	2.48e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MLEOMEED_03953	1.76e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_03954	7.53e-137	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_03955	5.47e-176	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLEOMEED_03956	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLEOMEED_03957	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLEOMEED_03958	2.68e-252	-	-	-	S	-	-	-	Glycosyl hydrolase
MLEOMEED_03959	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_03960	2.37e-199	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_03961	3.45e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_03962	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLEOMEED_03963	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MLEOMEED_03964	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLEOMEED_03965	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLEOMEED_03966	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLEOMEED_03967	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MLEOMEED_03968	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLEOMEED_03969	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MLEOMEED_03970	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLEOMEED_03971	2.4e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MLEOMEED_03972	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MLEOMEED_03973	2.38e-158	yvbI	-	-	M	-	-	-	Membrane
MLEOMEED_03974	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
MLEOMEED_03975	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MLEOMEED_03976	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MLEOMEED_03978	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLEOMEED_03979	4.16e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03980	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLEOMEED_03981	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLEOMEED_03982	1.6e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MLEOMEED_03988	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MLEOMEED_03989	1.55e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
MLEOMEED_03990	4.04e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLEOMEED_03991	3.82e-194	ybbH	-	-	K	-	-	-	transcriptional
MLEOMEED_03992	7.29e-304	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_03993	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MLEOMEED_03994	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MLEOMEED_03995	3.6e-306	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MLEOMEED_03996	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MLEOMEED_03997	9.23e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MLEOMEED_03998	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_03999	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLEOMEED_04000	4.01e-184	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MLEOMEED_04001	3.47e-205	ybaS	-	-	S	-	-	-	Na -dependent transporter
MLEOMEED_04003	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MLEOMEED_04004	5e-253	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
MLEOMEED_04005	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
MLEOMEED_04006	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
MLEOMEED_04007	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MLEOMEED_04008	0.0	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
MLEOMEED_04009	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
MLEOMEED_04010	1.25e-20	-	-	-	-	-	-	-	-
MLEOMEED_04012	2.08e-44	yoaF	-	-	-	-	-	-	-
MLEOMEED_04013	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLEOMEED_04014	3.41e-243	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLEOMEED_04015	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MLEOMEED_04016	1.11e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MLEOMEED_04017	5.91e-125	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLEOMEED_04018	1.34e-185	yoxB	-	-	-	-	-	-	-
MLEOMEED_04019	8.39e-57	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MLEOMEED_04020	7.94e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLEOMEED_04021	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLEOMEED_04022	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLEOMEED_04023	8.13e-263	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLEOMEED_04024	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_04025	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MLEOMEED_04026	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLEOMEED_04027	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLEOMEED_04028	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MLEOMEED_04029	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MLEOMEED_04030	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MLEOMEED_04031	1.14e-124	-	-	-	L	-	-	-	Integrase
MLEOMEED_04033	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MLEOMEED_04034	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
MLEOMEED_04035	7.83e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MLEOMEED_04036	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MLEOMEED_04037	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MLEOMEED_04038	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MLEOMEED_04039	4.08e-110	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MLEOMEED_04040	2.29e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MLEOMEED_04041	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MLEOMEED_04042	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLEOMEED_04043	4.79e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
MLEOMEED_04044	5.09e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLEOMEED_04045	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
MLEOMEED_04048	7.94e-22	ydhU	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
MLEOMEED_04049	1.12e-98	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MLEOMEED_04050	3.49e-273	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MLEOMEED_04051	1.93e-244	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MLEOMEED_04052	9.28e-219	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MLEOMEED_04053	1.9e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MLEOMEED_04054	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MLEOMEED_04055	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLEOMEED_04056	6.09e-70	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_04057	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MLEOMEED_04058	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MLEOMEED_04059	4.01e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MLEOMEED_04060	1.25e-236	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MLEOMEED_04061	1.43e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MLEOMEED_04063	9.93e-91	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MLEOMEED_04064	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MLEOMEED_04065	7.71e-166	-	-	-	-	-	-	-	-
MLEOMEED_04066	9.61e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLEOMEED_04067	8.92e-310	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MLEOMEED_04068	5.24e-158	ydhC	-	-	K	-	-	-	FCD
MLEOMEED_04069	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MLEOMEED_04070	5.97e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MLEOMEED_04071	1.15e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MLEOMEED_04072	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
MLEOMEED_04073	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MLEOMEED_04074	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MLEOMEED_04075	5.09e-119	-	-	-	S	-	-	-	DinB family
MLEOMEED_04076	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MLEOMEED_04077	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MLEOMEED_04078	2.49e-114	yycN	-	-	K	-	-	-	Acetyltransferase
MLEOMEED_04079	3.47e-71	-	-	-	S	-	-	-	DoxX-like family
MLEOMEED_04080	7.86e-132	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MLEOMEED_04081	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MLEOMEED_04082	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MLEOMEED_04083	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MLEOMEED_04084	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MLEOMEED_04085	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MLEOMEED_04087	5.33e-39	-	-	-	-	-	-	-	-
MLEOMEED_04088	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MLEOMEED_04089	9.63e-77	ydfQ	-	-	CO	-	-	-	Thioredoxin
MLEOMEED_04090	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MLEOMEED_04091	9.49e-239	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MLEOMEED_04092	3.45e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MLEOMEED_04093	3.15e-200	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLEOMEED_04094	2.13e-189	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MLEOMEED_04095	6.79e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MLEOMEED_04096	9.73e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MLEOMEED_04097	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MLEOMEED_04098	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLEOMEED_04099	4.11e-253	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MLEOMEED_04101	1.37e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLEOMEED_04102	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MLEOMEED_04103	5.97e-151	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MLEOMEED_04104	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_04105	3.05e-207	-	-	-	EG	-	-	-	EamA-like transporter family
MLEOMEED_04106	8.05e-191	-	-	-	J	-	-	-	GNAT acetyltransferase
MLEOMEED_04107	9.07e-297	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLEOMEED_04108	2.56e-76	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MLEOMEED_04109	3.74e-136	ydeS	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_04110	1.51e-261	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MLEOMEED_04111	2.44e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
MLEOMEED_04112	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
MLEOMEED_04113	1.68e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MLEOMEED_04114	1.33e-77	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MLEOMEED_04115	8.6e-138	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MLEOMEED_04116	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MLEOMEED_04117	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_04118	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
MLEOMEED_04119	6.11e-150	-	-	-	-	-	-	-	-
MLEOMEED_04120	1.26e-138	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MLEOMEED_04121	4.76e-72	ydeH	-	-	-	-	-	-	-
MLEOMEED_04122	1.19e-280	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MLEOMEED_04123	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLEOMEED_04124	2.87e-213	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MLEOMEED_04125	4.99e-224	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLEOMEED_04126	3.23e-215	-	-	-	K	-	-	-	AraC-like ligand binding domain
MLEOMEED_04127	2.47e-47	ydzE	-	-	EG	-	-	-	spore germination
MLEOMEED_04128	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MLEOMEED_04129	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MLEOMEED_04130	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family