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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IPCAFADI_00001	8.39e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPCAFADI_00002	2.43e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPCAFADI_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IPCAFADI_00004	1.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPCAFADI_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IPCAFADI_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPCAFADI_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPCAFADI_00008	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00011	4.9e-226	yaaC	-	-	S	-	-	-	YaaC-like Protein
IPCAFADI_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IPCAFADI_00013	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPCAFADI_00014	4.32e-201	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IPCAFADI_00015	2.35e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IPCAFADI_00016	2.51e-282	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPCAFADI_00017	1.94e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IPCAFADI_00019	3.43e-155	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IPCAFADI_00020	3.32e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IPCAFADI_00021	6.93e-269	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IPCAFADI_00022	2.67e-124	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IPCAFADI_00023	2.29e-107	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPCAFADI_00024	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPCAFADI_00025	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPCAFADI_00026	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPCAFADI_00027	3.13e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IPCAFADI_00028	7.53e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IPCAFADI_00029	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00032	1.5e-40	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IPCAFADI_00033	1.05e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IPCAFADI_00034	1.89e-227	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IPCAFADI_00035	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IPCAFADI_00036	7.14e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPCAFADI_00037	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00038	2.45e-93	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IPCAFADI_00039	1.65e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IPCAFADI_00040	5.2e-188	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IPCAFADI_00041	2.53e-55	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IPCAFADI_00042	9.4e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IPCAFADI_00043	8.14e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IPCAFADI_00044	6.62e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPCAFADI_00045	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IPCAFADI_00046	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPCAFADI_00047	2.05e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IPCAFADI_00048	4.81e-286	yabE	-	-	T	-	-	-	protein conserved in bacteria
IPCAFADI_00049	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPCAFADI_00050	6.91e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPCAFADI_00051	2.08e-186	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IPCAFADI_00052	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00053	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
IPCAFADI_00054	2.25e-205	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPCAFADI_00055	5.43e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IPCAFADI_00056	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IPCAFADI_00057	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IPCAFADI_00058	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPCAFADI_00059	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPCAFADI_00060	1.4e-133	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPCAFADI_00061	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPCAFADI_00062	5.24e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IPCAFADI_00063	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPCAFADI_00064	7.7e-117	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IPCAFADI_00065	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_00066	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IPCAFADI_00067	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IPCAFADI_00068	1.57e-65	yabP	-	-	S	-	-	-	Sporulation protein YabP
IPCAFADI_00069	1.79e-129	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IPCAFADI_00070	1.99e-73	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IPCAFADI_00071	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IPCAFADI_00074	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IPCAFADI_00075	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPCAFADI_00076	1.68e-229	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IPCAFADI_00077	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPCAFADI_00078	1.23e-118	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IPCAFADI_00079	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPCAFADI_00080	3.87e-176	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IPCAFADI_00081	1.52e-204	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPCAFADI_00082	8.56e-193	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IPCAFADI_00083	8.52e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IPCAFADI_00084	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPCAFADI_00085	6e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IPCAFADI_00086	9.5e-193	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IPCAFADI_00087	2.31e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IPCAFADI_00088	1.88e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPCAFADI_00089	5.12e-112	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPCAFADI_00090	9.99e-39	yazB	-	-	K	-	-	-	transcriptional
IPCAFADI_00091	8.33e-230	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPCAFADI_00092	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IPCAFADI_00093	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00103	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00104	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IPCAFADI_00105	8.58e-79	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IPCAFADI_00106	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IPCAFADI_00107	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IPCAFADI_00108	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPCAFADI_00109	3.64e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IPCAFADI_00110	1.85e-245	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IPCAFADI_00111	7.64e-155	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IPCAFADI_00112	1.23e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IPCAFADI_00113	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPCAFADI_00114	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IPCAFADI_00115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IPCAFADI_00116	1.61e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPCAFADI_00117	8.3e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPCAFADI_00118	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IPCAFADI_00119	4.65e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IPCAFADI_00120	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPCAFADI_00121	1.49e-123	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IPCAFADI_00122	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPCAFADI_00123	5.01e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPCAFADI_00124	2.72e-102	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPCAFADI_00125	8.15e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPCAFADI_00126	3.59e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IPCAFADI_00127	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCAFADI_00128	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCAFADI_00129	9.87e-45	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IPCAFADI_00130	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPCAFADI_00131	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPCAFADI_00132	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPCAFADI_00133	9.55e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPCAFADI_00134	1.41e-217	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IPCAFADI_00135	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IPCAFADI_00136	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPCAFADI_00137	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IPCAFADI_00138	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPCAFADI_00139	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPCAFADI_00140	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPCAFADI_00141	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPCAFADI_00142	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPCAFADI_00143	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPCAFADI_00144	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IPCAFADI_00145	1.35e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPCAFADI_00146	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPCAFADI_00147	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPCAFADI_00148	2.58e-120	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPCAFADI_00149	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPCAFADI_00150	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPCAFADI_00151	1.05e-119	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPCAFADI_00152	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPCAFADI_00153	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPCAFADI_00154	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IPCAFADI_00155	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IPCAFADI_00156	1.82e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPCAFADI_00157	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPCAFADI_00158	5.46e-181	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IPCAFADI_00159	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPCAFADI_00160	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IPCAFADI_00161	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPCAFADI_00162	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPCAFADI_00163	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCAFADI_00164	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IPCAFADI_00165	6.9e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCAFADI_00166	2.6e-185	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCAFADI_00167	2.18e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCAFADI_00168	3.42e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPCAFADI_00169	3.79e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPCAFADI_00170	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IPCAFADI_00171	1.82e-178	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IPCAFADI_00173	2.28e-99	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IPCAFADI_00174	2.13e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_00175	1.6e-247	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IPCAFADI_00176	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
IPCAFADI_00177	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IPCAFADI_00178	1.88e-175	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IPCAFADI_00179	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00185	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00186	4.21e-268	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IPCAFADI_00187	7.06e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCAFADI_00188	5.85e-226	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
IPCAFADI_00189	6.59e-255	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IPCAFADI_00190	7.5e-286	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IPCAFADI_00191	1.35e-216	ybaS	-	-	S	-	-	-	Na -dependent transporter
IPCAFADI_00192	1.27e-132	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IPCAFADI_00193	1.21e-223	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_00194	5.16e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_00195	6.45e-215	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IPCAFADI_00196	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IPCAFADI_00197	3.8e-292	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00198	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IPCAFADI_00199	5.08e-299	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IPCAFADI_00200	2.44e-302	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_00201	5.23e-205	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPCAFADI_00202	1.38e-107	ybbJ	-	-	J	-	-	-	acetyltransferase
IPCAFADI_00203	4.36e-98	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IPCAFADI_00209	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00210	1.7e-146	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IPCAFADI_00211	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPCAFADI_00212	1.03e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00213	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPCAFADI_00214	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPCAFADI_00215	1.42e-188	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IPCAFADI_00216	1.34e-127	-	-	-	S	-	-	-	ABC-2 family transporter protein
IPCAFADI_00217	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
IPCAFADI_00219	2.51e-118	-	-	-	H	-	-	-	Tellurite resistance protein TehB
IPCAFADI_00220	6.42e-201	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
IPCAFADI_00221	2.46e-134	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IPCAFADI_00222	2.32e-66	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IPCAFADI_00223	6.3e-90	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_00224	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_00225	1.22e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IPCAFADI_00226	2.22e-127	-	-	-	T	-	-	-	Histidine kinase
IPCAFADI_00227	9.15e-107	-	-	-	KT	-	-	-	helix_turn_helix, Lux Regulon
IPCAFADI_00228	4.75e-174	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00229	3.32e-181	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IPCAFADI_00230	2.32e-155	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IPCAFADI_00231	1.62e-19	-	-	-	-	-	-	-	-
IPCAFADI_00232	9.04e-73	-	-	-	Q	-	-	-	Thioesterase domain
IPCAFADI_00233	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
IPCAFADI_00234	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
IPCAFADI_00235	2.21e-149	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	PFAM Acyl transferase
IPCAFADI_00236	0.0	-	-	-	Q	-	-	-	Beta-ketoacyl synthase
IPCAFADI_00237	0.0	-	-	-	Q	-	-	-	Polyketide synthase modules and related proteins
IPCAFADI_00238	3.93e-115	-	-	-	Q	-	-	-	Flavin containing amine oxidoreductase
IPCAFADI_00239	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
IPCAFADI_00240	8.09e-50	-	-	-	Q	-	-	-	o-methyltransferase
IPCAFADI_00241	8.63e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
IPCAFADI_00242	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IPCAFADI_00243	2.01e-134	yqeB	-	-	-	-	-	-	-
IPCAFADI_00244	2.17e-52	ybyB	-	-	-	-	-	-	-
IPCAFADI_00245	0.0	ybeC	-	-	E	-	-	-	amino acid
IPCAFADI_00246	7.3e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IPCAFADI_00247	1.25e-207	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IPCAFADI_00248	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IPCAFADI_00249	2.47e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IPCAFADI_00250	5.33e-262	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IPCAFADI_00252	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IPCAFADI_00254	1.97e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPCAFADI_00255	3.06e-241	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
IPCAFADI_00256	7.3e-268	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPCAFADI_00257	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPCAFADI_00258	3.37e-110	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_00259	2.8e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IPCAFADI_00260	9.76e-52	ybfN	-	-	-	-	-	-	-
IPCAFADI_00261	1.2e-237	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IPCAFADI_00262	1.84e-266	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCAFADI_00263	2.56e-249	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IPCAFADI_00264	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPCAFADI_00265	1.09e-225	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IPCAFADI_00266	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IPCAFADI_00267	3.73e-239	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IPCAFADI_00268	2.93e-261	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_00269	2.43e-197	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IPCAFADI_00270	2.68e-157	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IPCAFADI_00271	2.32e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IPCAFADI_00272	1.43e-196	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCAFADI_00273	2.33e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IPCAFADI_00274	8.05e-231	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPCAFADI_00275	1.1e-81	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IPCAFADI_00276	3.92e-76	ydfQ	-	-	CO	-	-	-	Thioredoxin
IPCAFADI_00277	4.68e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IPCAFADI_00278	3.02e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IPCAFADI_00279	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IPCAFADI_00280	2.4e-33	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPCAFADI_00281	1.36e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPCAFADI_00282	1.4e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IPCAFADI_00283	2.25e-246	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IPCAFADI_00284	1.79e-306	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IPCAFADI_00285	3.35e-125	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IPCAFADI_00286	5.61e-139	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IPCAFADI_00287	6.43e-241	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IPCAFADI_00288	5.06e-208	yccK	-	-	C	-	-	-	Aldo keto reductase
IPCAFADI_00289	6.55e-210	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IPCAFADI_00290	2.75e-293	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00291	4.57e-316	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00292	2.64e-114	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IPCAFADI_00293	1.07e-243	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IPCAFADI_00294	1.67e-176	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IPCAFADI_00295	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPCAFADI_00296	1.06e-209	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IPCAFADI_00297	1.15e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IPCAFADI_00298	1.38e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IPCAFADI_00299	1.06e-231	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_00300	3.34e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IPCAFADI_00301	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IPCAFADI_00302	3.36e-136	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IPCAFADI_00303	4.28e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IPCAFADI_00304	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IPCAFADI_00305	3.9e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IPCAFADI_00306	1.08e-268	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IPCAFADI_00308	2.12e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IPCAFADI_00309	3.48e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IPCAFADI_00310	1.85e-206	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IPCAFADI_00311	3.32e-263	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IPCAFADI_00312	8.54e-289	ycgA	-	-	S	-	-	-	Membrane
IPCAFADI_00313	1.04e-53	ycgB	-	-	-	-	-	-	-
IPCAFADI_00314	6.6e-16	-	-	-	S	-	-	-	RDD family
IPCAFADI_00315	2.96e-06	yxaI1	-	-	S	-	-	-	RDD family
IPCAFADI_00316	5.2e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IPCAFADI_00317	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
IPCAFADI_00318	3.16e-97	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_00319	3.18e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
IPCAFADI_00320	9.48e-187	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IPCAFADI_00321	2.89e-308	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_00322	6.25e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IPCAFADI_00323	3.54e-189	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPCAFADI_00324	3.99e-165	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
IPCAFADI_00325	5.54e-287	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_00326	2.04e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPCAFADI_00327	5.23e-230	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IPCAFADI_00328	1.67e-177	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IPCAFADI_00329	2.64e-214	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IPCAFADI_00330	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPCAFADI_00331	8.6e-309	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCAFADI_00332	1.86e-286	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IPCAFADI_00333	2.81e-234	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IPCAFADI_00334	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IPCAFADI_00335	8.14e-73	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IPCAFADI_00336	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPCAFADI_00337	1.03e-282	yciC	-	-	S	-	-	-	GTPases (G3E family)
IPCAFADI_00338	9.13e-279	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPCAFADI_00339	3.65e-94	yckC	-	-	S	-	-	-	membrane
IPCAFADI_00340	2.16e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IPCAFADI_00341	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPCAFADI_00342	4.25e-85	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IPCAFADI_00343	7.65e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPCAFADI_00344	2.36e-119	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IPCAFADI_00345	5.83e-135	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IPCAFADI_00346	2.89e-84	hxlR	-	-	K	-	-	-	transcriptional
IPCAFADI_00347	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_00348	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_00349	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IPCAFADI_00350	4.66e-175	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IPCAFADI_00351	4.84e-313	-	-	-	E	-	-	-	Aminotransferase class I and II
IPCAFADI_00352	7.15e-156	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IPCAFADI_00353	1.59e-137	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IPCAFADI_00354	1.61e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPCAFADI_00355	5.85e-152	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPCAFADI_00356	1.28e-183	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IPCAFADI_00357	6.13e-199	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IPCAFADI_00358	1.99e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IPCAFADI_00359	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IPCAFADI_00360	6.46e-49	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IPCAFADI_00361	5.17e-95	yclD	-	-	-	-	-	-	-
IPCAFADI_00362	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IPCAFADI_00363	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IPCAFADI_00365	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
IPCAFADI_00366	3.1e-288	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IPCAFADI_00367	5.7e-243	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IPCAFADI_00368	4e-314	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_00369	2.47e-117	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCAFADI_00370	3.94e-179	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPCAFADI_00371	8.59e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPCAFADI_00372	6.27e-167	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00373	1.89e-274	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IPCAFADI_00374	4.93e-303	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IPCAFADI_00375	4.99e-153	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IPCAFADI_00376	5.38e-297	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IPCAFADI_00377	2.5e-162	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_00378	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
IPCAFADI_00379	9.92e-96	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPCAFADI_00381	0.000153	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPCAFADI_00382	1.83e-316	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPCAFADI_00383	1.06e-208	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_00384	1.99e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_00385	1.81e-172	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00386	3.24e-222	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IPCAFADI_00387	1.98e-313	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IPCAFADI_00388	1.37e-191	ycnC	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00389	8.01e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
IPCAFADI_00390	2.79e-59	ycnE	-	-	S	-	-	-	Monooxygenase
IPCAFADI_00391	1.08e-67	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPCAFADI_00392	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_00393	4.02e-283	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCAFADI_00394	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCAFADI_00395	3.93e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IPCAFADI_00396	1.28e-181	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_00397	6.58e-128	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00398	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IPCAFADI_00399	2.37e-135	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPCAFADI_00400	1.53e-69	-	-	-	-	-	-	-	-
IPCAFADI_00401	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IPCAFADI_00402	1.96e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IPCAFADI_00403	1.97e-255	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IPCAFADI_00404	2.03e-78	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IPCAFADI_00406	2.59e-175	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IPCAFADI_00407	1.22e-171	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IPCAFADI_00408	4.91e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IPCAFADI_00409	1.5e-186	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IPCAFADI_00410	3.02e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IPCAFADI_00411	8.93e-227	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IPCAFADI_00412	1.16e-162	kipR	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00413	4.84e-144	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IPCAFADI_00415	2.34e-72	yczJ	-	-	S	-	-	-	biosynthesis
IPCAFADI_00416	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IPCAFADI_00417	7.28e-212	ycsN	-	-	S	-	-	-	Oxidoreductase
IPCAFADI_00418	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IPCAFADI_00419	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IPCAFADI_00420	5.81e-200	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_00421	4.4e-122	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IPCAFADI_00422	2.59e-136	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPCAFADI_00423	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
IPCAFADI_00424	5.97e-175	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IPCAFADI_00425	2.67e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IPCAFADI_00426	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IPCAFADI_00427	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPCAFADI_00428	4.49e-239	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IPCAFADI_00429	2.74e-182	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IPCAFADI_00430	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
IPCAFADI_00431	4.35e-301	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IPCAFADI_00432	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IPCAFADI_00433	0.0	ydaO	-	-	E	-	-	-	amino acid
IPCAFADI_00434	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IPCAFADI_00437	1.06e-53	-	-	-	-	-	-	-	-
IPCAFADI_00438	1.03e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IPCAFADI_00440	9.31e-44	ydaT	-	-	-	-	-	-	-
IPCAFADI_00441	1.22e-172	ydbA	-	-	P	-	-	-	EcsC protein family
IPCAFADI_00442	1.5e-07	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IPCAFADI_00444	7.49e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IPCAFADI_00445	6.51e-247	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IPCAFADI_00446	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPCAFADI_00447	2.19e-145	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IPCAFADI_00448	3.75e-285	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCAFADI_00449	1.12e-226	ydbI	-	-	S	-	-	-	AI-2E family transporter
IPCAFADI_00450	2.18e-217	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00451	1.58e-163	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPCAFADI_00452	2.67e-69	ydbL	-	-	-	-	-	-	-
IPCAFADI_00453	7.84e-256	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IPCAFADI_00454	2.36e-17	-	-	-	S	-	-	-	Fur-regulated basic protein B
IPCAFADI_00455	6.11e-15	-	-	-	S	-	-	-	Fur-regulated basic protein A
IPCAFADI_00456	8.13e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCAFADI_00457	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
IPCAFADI_00458	7.23e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IPCAFADI_00459	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPCAFADI_00460	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPCAFADI_00461	2.24e-91	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IPCAFADI_00462	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IPCAFADI_00463	8.15e-136	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IPCAFADI_00464	1.17e-70	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPCAFADI_00465	4.13e-231	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IPCAFADI_00466	1.74e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPCAFADI_00467	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IPCAFADI_00468	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IPCAFADI_00469	1.71e-176	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IPCAFADI_00470	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IPCAFADI_00471	2.36e-87	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IPCAFADI_00472	4.02e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IPCAFADI_00473	3.28e-69	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IPCAFADI_00474	5.84e-110	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IPCAFADI_00475	2.67e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_00476	1.52e-136	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IPCAFADI_00477	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IPCAFADI_00478	1.78e-21	-	-	-	-	-	-	-	-
IPCAFADI_00479	2.33e-104	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IPCAFADI_00487	1.88e-69	-	-	-	-	-	-	-	-
IPCAFADI_00489	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
IPCAFADI_00490	4.15e-99	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IPCAFADI_00493	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IPCAFADI_00494	1.03e-94	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IPCAFADI_00495	2.03e-118	yrkC	-	-	G	-	-	-	Cupin domain
IPCAFADI_00496	2.49e-101	-	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00497	6.31e-126	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCAFADI_00498	3.05e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IPCAFADI_00499	1.89e-258	-	-	-	Q	-	-	-	imidazolonepropionase
IPCAFADI_00500	3.74e-75	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family transcriptional regulator
IPCAFADI_00501	2.53e-115	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IPCAFADI_00502	1.65e-210	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_00503	1.69e-239	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IPCAFADI_00504	1.66e-218	-	-	-	S	-	-	-	Patatin-like phospholipase
IPCAFADI_00506	4e-92	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_00507	6.42e-196	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IPCAFADI_00509	3.26e-204	-	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_00510	9.87e-204	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
IPCAFADI_00511	4.47e-109	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IPCAFADI_00512	1.33e-190	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IPCAFADI_00513	9.11e-168	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IPCAFADI_00515	1.25e-239	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IPCAFADI_00516	8.59e-205	-	-	-	S	-	-	-	Sodium Bile acid symporter family
IPCAFADI_00517	3.25e-251	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IPCAFADI_00518	1.3e-80	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IPCAFADI_00519	1.28e-277	nhaC_1	-	-	C	-	-	-	antiporter
IPCAFADI_00520	1.15e-314	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IPCAFADI_00521	5.82e-128	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_00523	8.8e-186	ydeK	-	-	EG	-	-	-	-transporter
IPCAFADI_00524	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_00525	1.41e-63	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IPCAFADI_00526	1.45e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
IPCAFADI_00527	1.62e-277	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPCAFADI_00528	2.27e-82	yraF	-	-	M	-	-	-	Spore coat protein
IPCAFADI_00529	2.74e-46	yraG	-	-	-	ko:K06440	-	ko00000	-
IPCAFADI_00530	4.1e-163	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
IPCAFADI_00531	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IPCAFADI_00532	1.69e-114	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IPCAFADI_00533	2.47e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_00534	8.95e-247	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
IPCAFADI_00535	1.02e-263	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IPCAFADI_00536	1.63e-280	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCAFADI_00537	1.19e-195	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPCAFADI_00538	3.01e-156	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPCAFADI_00539	7.81e-102	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IPCAFADI_00540	2.65e-180	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IPCAFADI_00541	1.07e-183	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPCAFADI_00542	1.4e-139	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IPCAFADI_00543	7.44e-135	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
IPCAFADI_00544	1.11e-211	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IPCAFADI_00545	1.03e-143	ydhC	-	-	K	-	-	-	FCD
IPCAFADI_00546	5.25e-279	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPCAFADI_00548	1.39e-311	pbpE	-	-	V	-	-	-	Beta-lactamase
IPCAFADI_00550	2.9e-126	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IPCAFADI_00551	1.68e-242	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IPCAFADI_00552	2.35e-147	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IPCAFADI_00553	1.71e-267	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IPCAFADI_00554	5.81e-63	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IPCAFADI_00555	4.14e-63	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IPCAFADI_00556	2.53e-127	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00557	0.0	ybeC	-	-	E	-	-	-	amino acid
IPCAFADI_00558	4.74e-209	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IPCAFADI_00559	3.85e-108	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IPCAFADI_00560	4.61e-227	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IPCAFADI_00561	1.98e-312	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPCAFADI_00564	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00567	2.09e-219	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IPCAFADI_00568	4.3e-111	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IPCAFADI_00569	2.69e-158	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IPCAFADI_00570	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IPCAFADI_00571	6.96e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPCAFADI_00572	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IPCAFADI_00573	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IPCAFADI_00574	1.51e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPCAFADI_00575	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPCAFADI_00576	7.81e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPCAFADI_00577	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IPCAFADI_00578	1.86e-161	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IPCAFADI_00579	1.24e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPCAFADI_00580	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPCAFADI_00581	4.81e-194	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
IPCAFADI_00582	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IPCAFADI_00583	1.09e-251	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IPCAFADI_00584	7.41e-310	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IPCAFADI_00585	2.63e-215	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IPCAFADI_00586	1.79e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IPCAFADI_00587	4.17e-141	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IPCAFADI_00588	6.17e-220	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPCAFADI_00589	2.67e-154	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IPCAFADI_00590	7.67e-199	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IPCAFADI_00591	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IPCAFADI_00592	3.33e-185	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IPCAFADI_00593	6.25e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00594	7.9e-246	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IPCAFADI_00595	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
IPCAFADI_00596	1.75e-188	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IPCAFADI_00598	2.76e-46	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IPCAFADI_00599	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IPCAFADI_00600	1.48e-306	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_00601	1.23e-15	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCAFADI_00602	1.71e-115	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IPCAFADI_00603	1.77e-58	-	-	-	S	-	-	-	ATP-grasp domain
IPCAFADI_00604	1.66e-59	-	-	-	G	-	-	-	Major Facilitator Superfamily
IPCAFADI_00605	2.02e-81	-	-	-	F	-	-	-	ATP-grasp domain
IPCAFADI_00606	2.05e-81	-	-	-	C	-	-	-	Taurine catabolism dioxygenase TauD, TfdA family
IPCAFADI_00607	1.25e-56	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
IPCAFADI_00608	1.1e-08	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Family 5
IPCAFADI_00609	9.33e-47	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCAFADI_00610	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IPCAFADI_00611	1.05e-256	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IPCAFADI_00612	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IPCAFADI_00613	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IPCAFADI_00614	3.03e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00615	8.71e-313	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IPCAFADI_00616	1.75e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IPCAFADI_00617	3.43e-165	yebC	-	-	M	-	-	-	Membrane
IPCAFADI_00619	7.62e-120	yebE	-	-	S	-	-	-	UPF0316 protein
IPCAFADI_00620	1.88e-39	yebG	-	-	S	-	-	-	NETI protein
IPCAFADI_00621	1.13e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPCAFADI_00622	6.65e-280	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPCAFADI_00623	1.75e-312	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPCAFADI_00624	5.39e-163	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IPCAFADI_00625	2.57e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCAFADI_00626	1.51e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCAFADI_00627	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCAFADI_00628	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPCAFADI_00629	2.08e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IPCAFADI_00630	4.74e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPCAFADI_00631	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IPCAFADI_00632	1.82e-294	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IPCAFADI_00633	4.48e-81	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IPCAFADI_00634	7.97e-173	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IPCAFADI_00635	2.32e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IPCAFADI_00636	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IPCAFADI_00637	3.07e-240	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IPCAFADI_00638	4.46e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00639	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IPCAFADI_00640	5.04e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IPCAFADI_00641	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IPCAFADI_00642	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPCAFADI_00643	1.59e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IPCAFADI_00644	4.68e-235	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IPCAFADI_00645	1.13e-155	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IPCAFADI_00646	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCAFADI_00647	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPCAFADI_00648	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPCAFADI_00649	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPCAFADI_00650	1.01e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00651	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPCAFADI_00652	6.02e-217	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPCAFADI_00653	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPCAFADI_00654	3.62e-06	-	-	-	-	-	-	-	-
IPCAFADI_00655	7.13e-69	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IPCAFADI_00656	1.75e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IPCAFADI_00657	1.37e-66	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IPCAFADI_00658	1.03e-53	-	-	-	S	-	-	-	Immunity protein 22
IPCAFADI_00659	4.11e-39	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IPCAFADI_00660	1.05e-26	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IPCAFADI_00661	4.24e-24	-	-	-	-	-	-	-	-
IPCAFADI_00662	2.54e-313	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IPCAFADI_00663	4.43e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IPCAFADI_00665	2.49e-139	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IPCAFADI_00666	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IPCAFADI_00667	1.34e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IPCAFADI_00668	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IPCAFADI_00669	2.79e-114	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IPCAFADI_00671	6.24e-148	yetF	-	-	S	-	-	-	membrane
IPCAFADI_00672	3.06e-70	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IPCAFADI_00673	2.87e-82	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_00674	2.8e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCAFADI_00675	9.52e-30	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IPCAFADI_00676	1.5e-72	-	-	-	H	-	-	-	riboflavin kinase activity
IPCAFADI_00677	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IPCAFADI_00679	3.57e-109	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_00680	7.87e-245	yetM	-	-	CH	-	-	-	FAD binding domain
IPCAFADI_00681	9.7e-252	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IPCAFADI_00682	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IPCAFADI_00683	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IPCAFADI_00684	3.43e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IPCAFADI_00685	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IPCAFADI_00686	2.38e-223	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IPCAFADI_00687	4.42e-270	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IPCAFADI_00688	2.31e-228	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IPCAFADI_00689	1.94e-271	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_00690	4.24e-306	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IPCAFADI_00691	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCAFADI_00692	3.69e-165	yfmS	-	-	NT	-	-	-	chemotaxis protein
IPCAFADI_00693	7.86e-211	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IPCAFADI_00694	3.06e-256	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_00695	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCAFADI_00696	7.44e-07	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IPCAFADI_00697	8.36e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IPCAFADI_00698	3.06e-249	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IPCAFADI_00699	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCAFADI_00700	1.63e-260	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IPCAFADI_00701	5.01e-233	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IPCAFADI_00702	9.03e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IPCAFADI_00703	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IPCAFADI_00704	6.14e-297	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IPCAFADI_00705	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IPCAFADI_00706	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
IPCAFADI_00707	2.04e-192	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IPCAFADI_00708	0.0	-	-	-	M	-	-	-	cell wall anchor domain
IPCAFADI_00709	1.3e-102	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IPCAFADI_00710	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPCAFADI_00711	4.96e-148	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IPCAFADI_00712	1.59e-216	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IPCAFADI_00714	1.24e-281	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IPCAFADI_00715	9.72e-183	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPCAFADI_00716	2.1e-270	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IPCAFADI_00717	1.81e-55	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IPCAFADI_00718	1.1e-152	yflK	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_00719	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IPCAFADI_00720	8.09e-26	yflI	-	-	-	-	-	-	-
IPCAFADI_00721	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IPCAFADI_00722	6.09e-174	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IPCAFADI_00723	6.88e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IPCAFADI_00724	8.21e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IPCAFADI_00725	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IPCAFADI_00726	6.69e-81	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IPCAFADI_00727	6.84e-103	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPCAFADI_00728	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IPCAFADI_00729	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IPCAFADI_00730	7.43e-312	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_00731	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPCAFADI_00732	4.99e-163	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IPCAFADI_00733	1.63e-155	frp	-	-	C	-	-	-	nitroreductase
IPCAFADI_00734	1.06e-160	yibF	-	-	S	-	-	-	YibE/F-like protein
IPCAFADI_00735	2.84e-237	yibE	-	-	S	-	-	-	YibE/F-like protein
IPCAFADI_00736	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IPCAFADI_00737	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IPCAFADI_00738	2.87e-226	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IPCAFADI_00739	3.11e-203	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPCAFADI_00740	9.12e-162	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPCAFADI_00741	3.83e-45	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_00742	7.02e-40	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IPCAFADI_00743	3.15e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPCAFADI_00744	2.71e-63	yfkI	-	-	S	-	-	-	gas vesicle protein
IPCAFADI_00745	6.23e-182	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IPCAFADI_00746	1.55e-273	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_00747	7.72e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IPCAFADI_00748	4.28e-181	yfkD	-	-	S	-	-	-	YfkD-like protein
IPCAFADI_00749	2.76e-184	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IPCAFADI_00750	1.56e-277	yfkA	-	-	S	-	-	-	YfkB-like domain
IPCAFADI_00751	7.99e-37	yfjT	-	-	-	-	-	-	-
IPCAFADI_00752	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IPCAFADI_00753	6.16e-181	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IPCAFADI_00755	5.27e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IPCAFADI_00756	1.51e-202	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IPCAFADI_00757	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPCAFADI_00758	7.45e-60	-	-	-	S	-	-	-	YfzA-like protein
IPCAFADI_00759	9.85e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPCAFADI_00760	1.85e-98	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IPCAFADI_00761	1.4e-237	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCAFADI_00762	9.85e-238	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCAFADI_00763	1.18e-257	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCAFADI_00764	1.04e-305	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCAFADI_00765	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IPCAFADI_00766	3.29e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IPCAFADI_00767	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPCAFADI_00768	5.21e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IPCAFADI_00769	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_00770	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
IPCAFADI_00771	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IPCAFADI_00772	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCAFADI_00773	3.2e-81	yfiD3	-	-	S	-	-	-	DoxX
IPCAFADI_00774	3.99e-197	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IPCAFADI_00775	8.11e-212	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPCAFADI_00776	1e-119	padR	-	-	K	-	-	-	transcriptional
IPCAFADI_00777	2.91e-125	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IPCAFADI_00778	1.19e-223	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IPCAFADI_00779	1.37e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IPCAFADI_00780	6.84e-121	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IPCAFADI_00781	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IPCAFADI_00782	3.5e-102	yfiV	-	-	K	-	-	-	transcriptional
IPCAFADI_00783	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPCAFADI_00784	3.64e-193	yfhB	-	-	S	-	-	-	PhzF family
IPCAFADI_00785	1.31e-134	yfhC	-	-	C	-	-	-	nitroreductase
IPCAFADI_00786	6.01e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
IPCAFADI_00788	4.54e-210	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IPCAFADI_00789	1.95e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IPCAFADI_00790	1.37e-61	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IPCAFADI_00791	2.25e-265	yfhI	-	-	EGP	-	-	-	-transporter
IPCAFADI_00793	2.32e-205	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IPCAFADI_00794	1.49e-58	yfhJ	-	-	S	-	-	-	WVELL protein
IPCAFADI_00795	3.98e-113	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IPCAFADI_00796	2.31e-45	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IPCAFADI_00797	2.1e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IPCAFADI_00798	1.11e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_00799	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IPCAFADI_00800	3.02e-229	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IPCAFADI_00801	1.1e-257	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IPCAFADI_00802	1.47e-49	yfhS	-	-	-	-	-	-	-
IPCAFADI_00803	1.73e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_00804	4.2e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IPCAFADI_00805	5.69e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
IPCAFADI_00806	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IPCAFADI_00807	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IPCAFADI_00808	3.05e-238	ygaE	-	-	S	-	-	-	Membrane
IPCAFADI_00809	3.13e-310	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IPCAFADI_00810	1.28e-107	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IPCAFADI_00811	6.8e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IPCAFADI_00812	2.71e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IPCAFADI_00813	2.43e-207	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IPCAFADI_00814	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_00831	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
IPCAFADI_00832	2.9e-159	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IPCAFADI_00833	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPCAFADI_00834	6.79e-308	ygaK	-	-	C	-	-	-	Berberine and berberine like
IPCAFADI_00836	4.82e-291	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
IPCAFADI_00837	6.66e-185	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPCAFADI_00838	3.58e-161	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_00839	9.44e-171	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_00840	1.27e-165	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_00841	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPCAFADI_00842	5.63e-226	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IPCAFADI_00843	2.39e-175	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IPCAFADI_00844	2.34e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IPCAFADI_00845	1.86e-182	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IPCAFADI_00846	4.77e-270	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IPCAFADI_00847	6.6e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPCAFADI_00848	3.99e-101	ygaO	-	-	-	-	-	-	-
IPCAFADI_00849	1.34e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_00851	7.43e-136	yhzB	-	-	S	-	-	-	B3/4 domain
IPCAFADI_00852	2.6e-281	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IPCAFADI_00853	2.06e-216	yhbB	-	-	S	-	-	-	Putative amidase domain
IPCAFADI_00854	1.39e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPCAFADI_00855	7.05e-134	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IPCAFADI_00856	7.16e-76	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IPCAFADI_00857	2.62e-85	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IPCAFADI_00858	1.23e-07	-	-	-	-	-	-	-	-
IPCAFADI_00859	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IPCAFADI_00860	1.23e-275	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IPCAFADI_00861	6.33e-93	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IPCAFADI_00862	2.98e-130	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IPCAFADI_00863	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IPCAFADI_00864	2.61e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IPCAFADI_00865	4.18e-65	yhcC	-	-	-	-	-	-	-
IPCAFADI_00866	6.61e-66	-	-	-	-	-	-	-	-
IPCAFADI_00867	3.06e-77	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_00868	1.47e-145	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00869	6.2e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00870	5.36e-201	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPCAFADI_00871	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IPCAFADI_00872	1.26e-166	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IPCAFADI_00873	2.67e-227	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IPCAFADI_00874	1.93e-303	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCAFADI_00875	8.59e-62	yhcM	-	-	-	-	-	-	-
IPCAFADI_00876	3.52e-116	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCAFADI_00877	4.46e-196	yhcP	-	-	-	-	-	-	-
IPCAFADI_00878	2.37e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
IPCAFADI_00879	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IPCAFADI_00880	2.83e-131	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IPCAFADI_00881	6.14e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IPCAFADI_00882	6.81e-86	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IPCAFADI_00883	3.54e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IPCAFADI_00884	1.14e-159	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IPCAFADI_00885	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPCAFADI_00886	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCAFADI_00887	3.35e-131	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IPCAFADI_00888	4.31e-194	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IPCAFADI_00889	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPCAFADI_00890	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPCAFADI_00891	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IPCAFADI_00892	2.61e-245	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_00893	7.64e-137	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCAFADI_00894	8.28e-108	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IPCAFADI_00895	6.73e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IPCAFADI_00896	6.68e-68	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IPCAFADI_00897	3.6e-277	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPCAFADI_00898	1.49e-93	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IPCAFADI_00899	2.84e-314	ygxB	-	-	M	-	-	-	Conserved TM helix
IPCAFADI_00900	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IPCAFADI_00901	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IPCAFADI_00902	8.87e-164	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPCAFADI_00903	3.99e-200	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_00904	4.42e-250	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPCAFADI_00905	1.77e-202	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_00906	1.1e-311	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IPCAFADI_00907	2.67e-263	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPCAFADI_00908	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IPCAFADI_00909	2.03e-249	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IPCAFADI_00910	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_00911	9.91e-137	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPCAFADI_00912	2.66e-305	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPCAFADI_00913	2.3e-91	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IPCAFADI_00914	1.14e-276	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IPCAFADI_00915	7.04e-288	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCAFADI_00916	2.04e-309	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPCAFADI_00917	8.31e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPCAFADI_00918	1.31e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPCAFADI_00919	3.77e-158	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IPCAFADI_00920	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IPCAFADI_00921	1.09e-251	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IPCAFADI_00922	1.56e-175	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IPCAFADI_00923	4.82e-192	nodB1	-	-	G	-	-	-	deacetylase
IPCAFADI_00924	2.12e-191	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IPCAFADI_00925	4.2e-106	pksA	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_00926	6.5e-116	ymcC	-	-	S	-	-	-	Membrane
IPCAFADI_00927	1.18e-108	-	-	-	T	-	-	-	universal stress protein
IPCAFADI_00928	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCAFADI_00929	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCAFADI_00930	1.12e-125	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IPCAFADI_00932	1.91e-38	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
IPCAFADI_00933	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IPCAFADI_00934	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IPCAFADI_00935	1.28e-255	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IPCAFADI_00936	6.89e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IPCAFADI_00937	2.72e-69	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IPCAFADI_00938	2.49e-197	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IPCAFADI_00939	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IPCAFADI_00940	4.26e-311	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
IPCAFADI_00941	2.13e-261	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IPCAFADI_00942	1.53e-112	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IPCAFADI_00944	1.54e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IPCAFADI_00945	1.21e-20	-	-	-	S	-	-	-	YhzD-like protein
IPCAFADI_00946	4.03e-208	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_00947	1.47e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IPCAFADI_00948	3.8e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IPCAFADI_00949	0.0	yhaN	-	-	L	-	-	-	AAA domain
IPCAFADI_00950	2.38e-224	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IPCAFADI_00951	4.77e-42	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IPCAFADI_00952	1.12e-182	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPCAFADI_00953	1.83e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IPCAFADI_00954	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IPCAFADI_00955	4.54e-144	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IPCAFADI_00956	1.58e-53	yhaH	-	-	S	-	-	-	YtxH-like protein
IPCAFADI_00957	2.55e-24	-	-	-	-	-	-	-	-
IPCAFADI_00958	7.9e-98	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IPCAFADI_00959	3.66e-253	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPCAFADI_00960	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IPCAFADI_00961	1.82e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IPCAFADI_00962	2.39e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IPCAFADI_00963	1.48e-153	ecsC	-	-	S	-	-	-	EcsC protein family
IPCAFADI_00964	1.01e-275	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IPCAFADI_00965	3.88e-302	yhfA	-	-	C	-	-	-	membrane
IPCAFADI_00966	4.23e-115	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IPCAFADI_00967	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPCAFADI_00968	1.31e-252	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPCAFADI_00969	8.34e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IPCAFADI_00970	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPCAFADI_00971	8.55e-129	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_00972	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IPCAFADI_00973	6.81e-225	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPCAFADI_00975	7.07e-249	yhfE	-	-	G	-	-	-	peptidase M42
IPCAFADI_00976	9.21e-287	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCAFADI_00977	8.36e-174	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IPCAFADI_00978	1.07e-240	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IPCAFADI_00979	9.24e-136	yhfK	-	-	GM	-	-	-	NmrA-like family
IPCAFADI_00980	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IPCAFADI_00981	2.67e-83	yhfM	-	-	-	-	-	-	-
IPCAFADI_00982	3.65e-291	yhfN	-	-	O	-	-	-	Peptidase M48
IPCAFADI_00983	3.54e-258	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPCAFADI_00984	5.23e-169	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IPCAFADI_00985	5.79e-132	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IPCAFADI_00986	3.94e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IPCAFADI_00987	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IPCAFADI_00988	2.83e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IPCAFADI_00989	5.97e-272	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IPCAFADI_00990	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IPCAFADI_00991	1.11e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_00992	2.24e-41	yhzC	-	-	S	-	-	-	IDEAL
IPCAFADI_00993	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IPCAFADI_00994	8.17e-72	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IPCAFADI_00995	5.22e-213	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
IPCAFADI_00996	1.31e-155	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IPCAFADI_00997	5.85e-56	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IPCAFADI_00998	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
IPCAFADI_00999	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCAFADI_01000	3.93e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IPCAFADI_01001	1.96e-77	yhjD	-	-	-	-	-	-	-
IPCAFADI_01002	5.89e-138	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_01003	1.3e-116	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPCAFADI_01004	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IPCAFADI_01005	4.89e-120	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_01006	2.76e-252	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IPCAFADI_01007	6.35e-260	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_01008	1.24e-138	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
IPCAFADI_01009	3.47e-108	yhjR	-	-	S	-	-	-	Rubrerythrin
IPCAFADI_01010	7.56e-153	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPCAFADI_01011	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IPCAFADI_01012	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IPCAFADI_01013	5.26e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPCAFADI_01014	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IPCAFADI_01015	3.36e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IPCAFADI_01016	5.49e-42	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IPCAFADI_01017	4.09e-78	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IPCAFADI_01018	1.44e-31	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IPCAFADI_01019	4.69e-106	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IPCAFADI_01020	2.91e-44	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IPCAFADI_01021	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IPCAFADI_01022	1.22e-13	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IPCAFADI_01023	1.85e-210	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IPCAFADI_01024	4.48e-78	yisL	-	-	S	-	-	-	UPF0344 protein
IPCAFADI_01025	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPCAFADI_01026	1.06e-114	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IPCAFADI_01027	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IPCAFADI_01028	2.37e-147	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IPCAFADI_01029	5.89e-308	yisQ	-	-	V	-	-	-	Mate efflux family protein
IPCAFADI_01030	2.51e-201	yisR	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01031	2.35e-180	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IPCAFADI_01032	4.89e-197	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IPCAFADI_01033	7.67e-102	yisT	-	-	S	-	-	-	DinB family
IPCAFADI_01034	1.38e-30	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_01035	6.5e-89	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IPCAFADI_01036	3.15e-56	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IPCAFADI_01037	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IPCAFADI_01038	7.44e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IPCAFADI_01039	1.63e-199	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IPCAFADI_01040	1.89e-185	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
IPCAFADI_01041	4.78e-299	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IPCAFADI_01042	3.71e-300	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IPCAFADI_01044	1.14e-195	yitS	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01045	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_01046	3.05e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IPCAFADI_01047	4.3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IPCAFADI_01048	1.49e-11	-	-	-	-	-	-	-	-
IPCAFADI_01049	1.63e-193	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IPCAFADI_01050	5.66e-182	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IPCAFADI_01051	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IPCAFADI_01052	1.4e-85	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IPCAFADI_01053	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IPCAFADI_01054	4.44e-117	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IPCAFADI_01055	1.48e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPCAFADI_01056	9.57e-286	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPCAFADI_01057	7.23e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IPCAFADI_01058	7.24e-264	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IPCAFADI_01059	5.59e-249	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IPCAFADI_01060	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IPCAFADI_01061	3.08e-221	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPCAFADI_01062	8.45e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
IPCAFADI_01063	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IPCAFADI_01064	6.87e-173	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IPCAFADI_01065	2.87e-126	yjaV	-	-	-	-	-	-	-
IPCAFADI_01066	8.66e-209	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IPCAFADI_01067	3.74e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IPCAFADI_01068	1.46e-37	yjzB	-	-	-	-	-	-	-
IPCAFADI_01069	7.31e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPCAFADI_01070	3.04e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCAFADI_01071	1.01e-178	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IPCAFADI_01072	5.41e-228	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01073	4.48e-232	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01074	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IPCAFADI_01075	8.55e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01076	7.81e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01077	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IPCAFADI_01078	8.74e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IPCAFADI_01079	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPCAFADI_01080	1.4e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01081	1.03e-209	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01082	1.96e-252	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01083	1.22e-217	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01084	1.11e-282	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
IPCAFADI_01085	1.04e-130	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCAFADI_01086	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPCAFADI_01087	5.59e-141	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IPCAFADI_01088	1.33e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPCAFADI_01089	2.79e-257	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IPCAFADI_01090	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IPCAFADI_01091	1.28e-26	-	-	-	-	-	-	-	-
IPCAFADI_01092	9.23e-215	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPCAFADI_01093	2.77e-90	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IPCAFADI_01094	9.82e-140	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPCAFADI_01095	1.99e-118	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01096	3.37e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IPCAFADI_01097	3.67e-138	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IPCAFADI_01098	6.92e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPCAFADI_01099	4.87e-204	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IPCAFADI_01100	1.56e-176	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IPCAFADI_01101	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPCAFADI_01102	2.06e-170	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IPCAFADI_01103	3.03e-134	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IPCAFADI_01104	2.05e-255	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IPCAFADI_01105	2.63e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
IPCAFADI_01106	6.04e-172	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IPCAFADI_01107	8.27e-227	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPCAFADI_01108	1.48e-180	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IPCAFADI_01109	1.38e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IPCAFADI_01110	4.09e-99	yjbX	-	-	S	-	-	-	Spore coat protein
IPCAFADI_01111	1.37e-104	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IPCAFADI_01112	1.75e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IPCAFADI_01113	5.05e-98	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IPCAFADI_01114	3.52e-44	cotW	-	-	-	ko:K06341	-	ko00000	-
IPCAFADI_01115	4.61e-69	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
IPCAFADI_01116	4.84e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IPCAFADI_01120	1.22e-49	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IPCAFADI_01121	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPCAFADI_01122	1.62e-44	-	-	-	-	-	-	-	-
IPCAFADI_01123	4.79e-169	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IPCAFADI_01124	6.79e-138	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IPCAFADI_01125	8.87e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IPCAFADI_01126	3.06e-70	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IPCAFADI_01127	1.46e-44	-	-	-	K	-	-	-	SpoVT / AbrB like domain
IPCAFADI_01128	4.81e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCAFADI_01129	4.03e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IPCAFADI_01130	1.08e-158	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IPCAFADI_01131	4.4e-268	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPCAFADI_01132	3.52e-274	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPCAFADI_01134	3.16e-26	-	-	-	-	-	-	-	-
IPCAFADI_01137	6.25e-11	tnpB	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPCAFADI_01138	4.06e-35	tnpB	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPCAFADI_01139	4.31e-29	tnpC	-	-	S	-	-	-	Transposition regulatory protein TnpC
IPCAFADI_01140	2.1e-26	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IPCAFADI_01141	1.4e-69	-	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	PFAM Ketopantoate reductase
IPCAFADI_01145	9.28e-197	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IPCAFADI_01146	2.88e-59	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IPCAFADI_01147	4.93e-305	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
IPCAFADI_01148	1.23e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_01150	5.59e-133	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IPCAFADI_01152	5.29e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IPCAFADI_01153	1.42e-79	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IPCAFADI_01154	1.65e-121	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IPCAFADI_01155	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
IPCAFADI_01156	1.12e-110	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPCAFADI_01157	3.81e-274	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPCAFADI_01158	8.93e-272	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPCAFADI_01159	1.73e-40	-	-	-	-	-	-	-	-
IPCAFADI_01160	1.76e-181	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IPCAFADI_01161	2.45e-150	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IPCAFADI_01162	2.23e-159	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01163	1.21e-219	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IPCAFADI_01164	1.36e-106	yjlB	-	-	S	-	-	-	Cupin domain
IPCAFADI_01165	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPCAFADI_01166	8.37e-278	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPCAFADI_01167	6.31e-112	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IPCAFADI_01168	2.3e-231	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IPCAFADI_01169	4.57e-09	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IPCAFADI_01170	4.83e-190	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IPCAFADI_01171	8.81e-165	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPCAFADI_01172	5.44e-99	yjoA	-	-	S	-	-	-	DinB family
IPCAFADI_01173	1.05e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPCAFADI_01175	2.71e-211	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IPCAFADI_01176	1.3e-78	yjqA	-	-	S	-	-	-	Bacterial PH domain
IPCAFADI_01177	3.66e-126	yjqB	-	-	S	-	-	-	phage-related replication protein
IPCAFADI_01178	2.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IPCAFADI_01179	1.27e-72	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPCAFADI_01181	2.39e-184	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IPCAFADI_01185	3.15e-105	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IPCAFADI_01186	2.77e-139	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IPCAFADI_01187	1.43e-264	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IPCAFADI_01188	6.02e-303	xkdE3	-	-	S	-	-	-	portal protein
IPCAFADI_01189	2.09e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IPCAFADI_01190	4.8e-202	xkdG	-	-	S	-	-	-	Phage capsid family
IPCAFADI_01191	1.26e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IPCAFADI_01192	5.29e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IPCAFADI_01193	6.9e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPCAFADI_01194	6.36e-76	xkdJ	-	-	-	-	-	-	-
IPCAFADI_01195	1.57e-20	-	-	-	-	-	-	-	-
IPCAFADI_01196	1.33e-286	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IPCAFADI_01197	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
IPCAFADI_01198	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IPCAFADI_01199	4.33e-27	-	-	-	-	-	-	-	-
IPCAFADI_01200	1.84e-271	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IPCAFADI_01201	1.88e-144	xkdP	-	-	S	-	-	-	Lysin motif
IPCAFADI_01202	2.78e-208	xkdQ	-	-	G	-	-	-	NLP P60 protein
IPCAFADI_01203	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IPCAFADI_01204	1.65e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IPCAFADI_01205	2.53e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IPCAFADI_01206	1.37e-110	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IPCAFADI_01207	1.48e-36	-	-	-	-	-	-	-	-
IPCAFADI_01208	5.56e-195	-	-	-	-	-	-	-	-
IPCAFADI_01210	1.05e-36	xkdX	-	-	-	-	-	-	-
IPCAFADI_01211	2.01e-165	xepA	-	-	-	-	-	-	-
IPCAFADI_01212	6.44e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IPCAFADI_01213	2.62e-49	xhlB	-	-	S	-	-	-	SPP1 phage holin
IPCAFADI_01214	1.2e-206	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_01215	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IPCAFADI_01216	1.74e-168	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IPCAFADI_01217	4.77e-224	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IPCAFADI_01218	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IPCAFADI_01219	8.6e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IPCAFADI_01220	2.04e-226	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPCAFADI_01221	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPCAFADI_01222	9.66e-224	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_01224	5.96e-266	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCAFADI_01225	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IPCAFADI_01226	1.7e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IPCAFADI_01227	2.2e-201	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01228	2.76e-219	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCAFADI_01229	9.42e-234	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01230	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPCAFADI_01231	5.18e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IPCAFADI_01232	9.49e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IPCAFADI_01233	9.02e-201	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPCAFADI_01234	1.74e-226	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_01235	7.13e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IPCAFADI_01236	3.05e-181	ykgA	-	-	E	-	-	-	Amidinotransferase
IPCAFADI_01237	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IPCAFADI_01238	4.45e-122	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPCAFADI_01239	2.03e-64	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IPCAFADI_01240	1.73e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IPCAFADI_01241	3.09e-213	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IPCAFADI_01242	6.62e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPCAFADI_01243	4.7e-282	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPCAFADI_01244	3.82e-90	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IPCAFADI_01245	4.15e-103	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IPCAFADI_01246	4.36e-89	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IPCAFADI_01247	1.03e-70	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IPCAFADI_01249	3.18e-262	-	-	-	M	-	-	-	Glycosyl transferase family 2
IPCAFADI_01250	3.21e-135	-	-	-	K	-	-	-	Collagen triple helix repeat
IPCAFADI_01251	2.07e-263	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_01252	2.92e-151	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IPCAFADI_01253	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPCAFADI_01254	3.93e-221	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPCAFADI_01255	2.83e-177	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCAFADI_01256	2.15e-160	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IPCAFADI_01257	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_01258	4.28e-122	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IPCAFADI_01259	6.18e-301	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IPCAFADI_01261	3.93e-306	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IPCAFADI_01262	3.53e-69	tnrA	-	-	K	-	-	-	transcriptional
IPCAFADI_01263	2.72e-24	-	-	-	-	-	-	-	-
IPCAFADI_01264	3.57e-35	ykoL	-	-	-	-	-	-	-
IPCAFADI_01265	3.16e-104	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IPCAFADI_01266	1.81e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IPCAFADI_01267	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IPCAFADI_01268	4.47e-198	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IPCAFADI_01269	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IPCAFADI_01270	5.69e-120	ykoX	-	-	S	-	-	-	membrane-associated protein
IPCAFADI_01271	1.16e-163	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IPCAFADI_01272	1.21e-162	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_01273	6.08e-222	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IPCAFADI_01274	3.31e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IPCAFADI_01275	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IPCAFADI_01276	4.28e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IPCAFADI_01277	1.92e-301	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IPCAFADI_01278	6.77e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPCAFADI_01279	1.37e-26	ykzE	-	-	-	-	-	-	-
IPCAFADI_01280	4.18e-238	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IPCAFADI_01281	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_01282	2.63e-104	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPCAFADI_01284	4.96e-248	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IPCAFADI_01285	9.79e-278	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IPCAFADI_01286	7.28e-176	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPCAFADI_01287	4.36e-283	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IPCAFADI_01288	2.4e-283	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IPCAFADI_01289	2.14e-171	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IPCAFADI_01290	1.98e-141	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IPCAFADI_01291	1.14e-118	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IPCAFADI_01292	3.44e-16	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
IPCAFADI_01293	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IPCAFADI_01294	2.75e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IPCAFADI_01295	6.88e-162	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IPCAFADI_01296	5.49e-174	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IPCAFADI_01297	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IPCAFADI_01298	3.06e-222	ykvI	-	-	S	-	-	-	membrane
IPCAFADI_01299	1.35e-230	-	-	-	-	-	-	-	-
IPCAFADI_01300	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IPCAFADI_01301	8.88e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IPCAFADI_01302	1.69e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IPCAFADI_01303	3.64e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IPCAFADI_01304	2.76e-55	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IPCAFADI_01305	1.56e-34	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01306	8.76e-38	-	-	-	-	-	-	-	-
IPCAFADI_01307	5.23e-136	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IPCAFADI_01308	4.04e-301	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_01309	6.24e-107	stoA	-	-	CO	-	-	-	thiol-disulfide
IPCAFADI_01310	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IPCAFADI_01311	2.14e-259	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IPCAFADI_01313	1.79e-218	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01314	8.93e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IPCAFADI_01315	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_01316	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IPCAFADI_01317	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPCAFADI_01318	1.22e-48	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01319	2.29e-252	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IPCAFADI_01320	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPCAFADI_01321	6.67e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IPCAFADI_01322	3.43e-167	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IPCAFADI_01323	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IPCAFADI_01324	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_01325	5.43e-274	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IPCAFADI_01326	2.22e-15	-	-	-	-	-	-	-	-
IPCAFADI_01327	4.55e-212	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IPCAFADI_01328	1.45e-107	ykyB	-	-	S	-	-	-	YkyB-like protein
IPCAFADI_01329	8.52e-304	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_01330	4.23e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01331	2.44e-186	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IPCAFADI_01332	1.96e-177	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_01333	3.52e-293	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IPCAFADI_01334	2.11e-49	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01335	1.4e-116	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IPCAFADI_01336	2.63e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IPCAFADI_01337	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
IPCAFADI_01338	1.08e-214	ccpC	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01339	9.78e-112	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IPCAFADI_01340	2.07e-205	ykuO	-	-	-	-	-	-	-
IPCAFADI_01341	1.11e-96	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IPCAFADI_01342	6.8e-128	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPCAFADI_01343	2.46e-270	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPCAFADI_01344	1.25e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IPCAFADI_01345	5.77e-177	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IPCAFADI_01346	9.43e-94	ykuV	-	-	CO	-	-	-	thiol-disulfide
IPCAFADI_01348	3.55e-125	rok	-	-	K	-	-	-	Repressor of ComK
IPCAFADI_01349	5.65e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
IPCAFADI_01350	3.69e-128	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IPCAFADI_01351	9.1e-237	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPCAFADI_01352	7.3e-305	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IPCAFADI_01353	5.29e-112	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IPCAFADI_01354	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IPCAFADI_01355	4.7e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IPCAFADI_01356	4.95e-135	yknW	-	-	S	-	-	-	Yip1 domain
IPCAFADI_01357	7e-224	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPCAFADI_01358	3.39e-157	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_01359	1.11e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IPCAFADI_01360	2.55e-167	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01361	2.16e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IPCAFADI_01362	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IPCAFADI_01363	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPCAFADI_01364	2.49e-48	ykoA	-	-	-	-	-	-	-
IPCAFADI_01365	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCAFADI_01366	1.39e-201	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPCAFADI_01367	2.32e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IPCAFADI_01368	5.41e-19	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IPCAFADI_01369	4.34e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IPCAFADI_01370	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IPCAFADI_01371	1.07e-299	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IPCAFADI_01372	6.61e-191	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IPCAFADI_01373	1.96e-147	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IPCAFADI_01374	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPCAFADI_01375	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPCAFADI_01376	7.4e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IPCAFADI_01377	3.67e-179	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IPCAFADI_01378	6.32e-128	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPCAFADI_01379	4.93e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPCAFADI_01380	6.56e-84	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IPCAFADI_01381	1.04e-249	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCAFADI_01382	5.84e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCAFADI_01383	1.5e-294	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCAFADI_01384	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCAFADI_01385	6.84e-60	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IPCAFADI_01386	2.25e-171	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IPCAFADI_01387	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IPCAFADI_01388	5.44e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IPCAFADI_01389	3.88e-153	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IPCAFADI_01390	7.89e-32	ykzI	-	-	-	-	-	-	-
IPCAFADI_01391	9.1e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IPCAFADI_01392	6.45e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IPCAFADI_01393	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IPCAFADI_01395	1.41e-57	ylaE	-	-	-	-	-	-	-
IPCAFADI_01396	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IPCAFADI_01397	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IPCAFADI_01398	6.99e-65	-	-	-	S	-	-	-	YlaH-like protein
IPCAFADI_01399	7.95e-45	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01400	7.64e-129	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCAFADI_01401	1.43e-308	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IPCAFADI_01402	4.45e-104	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPCAFADI_01403	1.66e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IPCAFADI_01404	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IPCAFADI_01405	8.77e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IPCAFADI_01406	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPCAFADI_01407	1.58e-210	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IPCAFADI_01408	4.18e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPCAFADI_01409	2.28e-250	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IPCAFADI_01410	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPCAFADI_01411	3.43e-141	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IPCAFADI_01412	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IPCAFADI_01413	3.17e-206	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IPCAFADI_01414	3.26e-76	ylbA	-	-	S	-	-	-	YugN-like family
IPCAFADI_01415	2.75e-95	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IPCAFADI_01416	3.22e-245	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IPCAFADI_01417	1.11e-82	ylbD	-	-	S	-	-	-	Putative coat protein
IPCAFADI_01418	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IPCAFADI_01419	1.85e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IPCAFADI_01420	4.62e-56	ylbG	-	-	S	-	-	-	UPF0298 protein
IPCAFADI_01421	1.74e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IPCAFADI_01422	2.38e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPCAFADI_01423	5.72e-266	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IPCAFADI_01424	1.67e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IPCAFADI_01425	1.56e-233	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IPCAFADI_01426	6.68e-282	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IPCAFADI_01427	1.91e-114	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IPCAFADI_01428	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IPCAFADI_01429	1.65e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IPCAFADI_01430	2.68e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IPCAFADI_01431	2.31e-192	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPCAFADI_01432	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IPCAFADI_01433	9.07e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IPCAFADI_01434	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPCAFADI_01435	2.81e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
IPCAFADI_01436	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IPCAFADI_01437	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IPCAFADI_01438	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPCAFADI_01439	2.36e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPCAFADI_01440	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPCAFADI_01441	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IPCAFADI_01442	1.63e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPCAFADI_01443	2.63e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IPCAFADI_01444	3.58e-168	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPCAFADI_01445	3.7e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPCAFADI_01446	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPCAFADI_01447	3.37e-95	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IPCAFADI_01448	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IPCAFADI_01449	7.24e-212	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IPCAFADI_01450	3.64e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_01451	3.8e-178	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_01452	1.49e-182	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IPCAFADI_01453	1.22e-310	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IPCAFADI_01454	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
IPCAFADI_01455	4.01e-198	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IPCAFADI_01456	3.25e-155	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPCAFADI_01457	8.91e-83	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPCAFADI_01458	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IPCAFADI_01459	5.63e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IPCAFADI_01460	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IPCAFADI_01461	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPCAFADI_01462	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IPCAFADI_01463	8.42e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPCAFADI_01464	2.97e-213	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IPCAFADI_01465	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPCAFADI_01466	1.49e-291	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IPCAFADI_01467	1.84e-207	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IPCAFADI_01468	2.77e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPCAFADI_01469	4.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IPCAFADI_01470	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IPCAFADI_01471	3.96e-178	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IPCAFADI_01472	1.17e-218	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPCAFADI_01473	1.17e-159	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPCAFADI_01474	1.17e-144	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPCAFADI_01475	7.81e-178	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IPCAFADI_01476	6.41e-224	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IPCAFADI_01477	1.19e-281	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IPCAFADI_01478	1.31e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IPCAFADI_01479	1.05e-178	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IPCAFADI_01480	2.37e-177	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IPCAFADI_01481	1.07e-97	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IPCAFADI_01482	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IPCAFADI_01483	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IPCAFADI_01484	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IPCAFADI_01485	8e-194	yloC	-	-	S	-	-	-	stress-induced protein
IPCAFADI_01486	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IPCAFADI_01487	1.16e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IPCAFADI_01488	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPCAFADI_01489	1.35e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPCAFADI_01490	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPCAFADI_01491	3.38e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPCAFADI_01492	6.66e-215	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPCAFADI_01493	2.31e-312	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPCAFADI_01494	3.58e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IPCAFADI_01495	3.32e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IPCAFADI_01496	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IPCAFADI_01497	2e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPCAFADI_01498	1.69e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IPCAFADI_01499	6.63e-147	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IPCAFADI_01500	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IPCAFADI_01501	2.12e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01502	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IPCAFADI_01503	1.69e-152	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IPCAFADI_01504	3.26e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IPCAFADI_01505	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPCAFADI_01506	2.96e-119	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IPCAFADI_01507	2.28e-223	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPCAFADI_01508	3.45e-214	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IPCAFADI_01509	1.17e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IPCAFADI_01510	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPCAFADI_01511	2.48e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPCAFADI_01512	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IPCAFADI_01513	2.09e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPCAFADI_01514	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPCAFADI_01515	1.64e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPCAFADI_01516	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IPCAFADI_01517	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IPCAFADI_01518	5.66e-79	ylqD	-	-	S	-	-	-	YlqD protein
IPCAFADI_01519	7.2e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPCAFADI_01520	1.28e-172	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IPCAFADI_01521	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPCAFADI_01522	1.4e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPCAFADI_01523	1.08e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPCAFADI_01524	0.0	ylqG	-	-	-	-	-	-	-
IPCAFADI_01525	9.86e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IPCAFADI_01526	9.61e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IPCAFADI_01527	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IPCAFADI_01528	2.16e-208	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IPCAFADI_01529	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPCAFADI_01530	1.05e-311	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IPCAFADI_01531	1.42e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IPCAFADI_01532	1.43e-118	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPCAFADI_01533	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPCAFADI_01534	7.94e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IPCAFADI_01535	3.14e-81	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IPCAFADI_01536	1.46e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IPCAFADI_01537	5.06e-49	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IPCAFADI_01538	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IPCAFADI_01539	3.52e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCAFADI_01540	1.14e-114	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IPCAFADI_01541	2.47e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IPCAFADI_01542	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IPCAFADI_01543	1.48e-80	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IPCAFADI_01544	4.31e-239	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IPCAFADI_01545	4.2e-91	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IPCAFADI_01546	2.56e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IPCAFADI_01547	4.27e-77	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IPCAFADI_01548	5.2e-228	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCAFADI_01549	4.34e-232	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCAFADI_01550	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IPCAFADI_01551	6.3e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IPCAFADI_01552	9.98e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IPCAFADI_01553	9.02e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IPCAFADI_01554	5.49e-166	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IPCAFADI_01555	1.9e-237	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPCAFADI_01556	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPCAFADI_01557	3.95e-211	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IPCAFADI_01558	3.52e-197	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IPCAFADI_01559	1.15e-238	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IPCAFADI_01560	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IPCAFADI_01561	1.01e-104	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IPCAFADI_01562	1.39e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IPCAFADI_01563	1.93e-111	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IPCAFADI_01564	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_01565	7.25e-82	ylxL	-	-	-	-	-	-	-
IPCAFADI_01566	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IPCAFADI_01567	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPCAFADI_01568	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IPCAFADI_01569	1.59e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPCAFADI_01570	2.49e-183	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPCAFADI_01571	2.1e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IPCAFADI_01572	4.96e-270	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IPCAFADI_01573	4.47e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IPCAFADI_01574	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPCAFADI_01575	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPCAFADI_01576	6.62e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IPCAFADI_01577	3.32e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IPCAFADI_01578	1.37e-55	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IPCAFADI_01579	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IPCAFADI_01580	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPCAFADI_01581	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IPCAFADI_01582	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPCAFADI_01583	7.56e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPCAFADI_01584	3.5e-221	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IPCAFADI_01585	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPCAFADI_01586	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IPCAFADI_01587	7.71e-228	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IPCAFADI_01588	9.39e-296	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IPCAFADI_01589	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IPCAFADI_01590	5.04e-201	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IPCAFADI_01591	5.97e-132	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IPCAFADI_01592	1.53e-243	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPCAFADI_01593	1.83e-278	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPCAFADI_01594	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPCAFADI_01595	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPCAFADI_01596	3.81e-167	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IPCAFADI_01597	7.4e-41	-	-	-	S	-	-	-	YlzJ-like protein
IPCAFADI_01598	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IPCAFADI_01599	4.81e-167	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01600	9.23e-289	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_01601	6.68e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_01602	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IPCAFADI_01603	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
IPCAFADI_01604	2.54e-304	ymfH	-	-	S	-	-	-	zinc protease
IPCAFADI_01605	6.79e-163	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IPCAFADI_01606	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IPCAFADI_01607	1.28e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IPCAFADI_01608	1.94e-167	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IPCAFADI_01609	4.75e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPCAFADI_01610	1.55e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IPCAFADI_01611	8.4e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPCAFADI_01612	2.49e-259	pbpX	-	-	V	-	-	-	Beta-lactamase
IPCAFADI_01613	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IPCAFADI_01614	3.06e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IPCAFADI_01615	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IPCAFADI_01616	7.62e-247	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IPCAFADI_01617	3.37e-272	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPCAFADI_01618	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPCAFADI_01619	1.17e-85	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IPCAFADI_01620	9.66e-117	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IPCAFADI_01621	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPCAFADI_01622	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPCAFADI_01623	2.54e-171	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPCAFADI_01624	4.35e-50	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
IPCAFADI_01625	7.12e-98	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
IPCAFADI_01627	2.56e-60	-	-	-	-	-	-	-	-
IPCAFADI_01629	1.76e-22	-	-	-	V	-	-	-	VanZ like family
IPCAFADI_01630	9.39e-78	-	-	-	E	-	-	-	Glyoxalase-like domain
IPCAFADI_01632	2e-65	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IPCAFADI_01634	1.98e-54	-	-	-	-	-	-	-	-
IPCAFADI_01636	1.94e-39	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPCAFADI_01637	7.97e-43	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IPCAFADI_01638	2.52e-160	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
IPCAFADI_01639	3.42e-200	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IPCAFADI_01640	1.12e-218	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
IPCAFADI_01641	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IPCAFADI_01642	8.76e-48	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
IPCAFADI_01643	2.86e-306	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
IPCAFADI_01644	1.49e-178	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
IPCAFADI_01645	2.69e-177	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
IPCAFADI_01646	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IPCAFADI_01647	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
IPCAFADI_01648	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
IPCAFADI_01649	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IPCAFADI_01650	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
IPCAFADI_01651	1.3e-282	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPCAFADI_01652	8.95e-95	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPCAFADI_01653	1.53e-149	yoaK	-	-	S	-	-	-	Membrane
IPCAFADI_01654	5.4e-80	ymzB	-	-	-	-	-	-	-
IPCAFADI_01655	9.4e-317	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IPCAFADI_01656	2.64e-07	-	-	-	-	-	-	-	-
IPCAFADI_01657	7.57e-152	ymaC	-	-	S	-	-	-	Replication protein
IPCAFADI_01658	3.2e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IPCAFADI_01659	1.45e-69	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IPCAFADI_01660	1e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IPCAFADI_01662	3.7e-71	ymaF	-	-	S	-	-	-	YmaF family
IPCAFADI_01663	1.24e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPCAFADI_01664	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IPCAFADI_01665	1.31e-53	-	-	-	-	-	-	-	-
IPCAFADI_01666	9.42e-29	ymzA	-	-	-	-	-	-	-
IPCAFADI_01667	4.43e-77	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IPCAFADI_01668	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCAFADI_01669	5.94e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCAFADI_01670	7.39e-131	ymaB	-	-	S	-	-	-	MutT family
IPCAFADI_01671	4.05e-137	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_01672	2.58e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IPCAFADI_01673	3.36e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPCAFADI_01674	5.35e-307	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IPCAFADI_01675	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IPCAFADI_01676	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IPCAFADI_01677	2.71e-150	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IPCAFADI_01678	7.3e-270	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPCAFADI_01679	6.28e-316	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IPCAFADI_01680	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IPCAFADI_01681	7.5e-264	xylR	-	-	GK	-	-	-	ROK family
IPCAFADI_01682	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IPCAFADI_01683	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IPCAFADI_01684	3.8e-151	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IPCAFADI_01685	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IPCAFADI_01686	1.29e-114	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IPCAFADI_01687	6.24e-224	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IPCAFADI_01689	7.33e-250	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPCAFADI_01692	3.23e-88	dinB	-	-	S	-	-	-	DinB family
IPCAFADI_01693	1.07e-230	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IPCAFADI_01694	1.69e-59	-	-	-	-	-	-	-	-
IPCAFADI_01695	1.74e-11	-	-	-	-	-	-	-	-
IPCAFADI_01696	2.42e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
IPCAFADI_01700	4.27e-29	-	-	-	-	-	-	-	-
IPCAFADI_01701	1.93e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IPCAFADI_01702	9.12e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IPCAFADI_01703	1.56e-237	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_01704	3.2e-150	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
IPCAFADI_01705	6.53e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPCAFADI_01706	3.97e-119	yvgO	-	-	-	-	-	-	-
IPCAFADI_01708	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
IPCAFADI_01709	1.33e-43	-	-	-	S	-	-	-	TM2 domain
IPCAFADI_01710	2.29e-97	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IPCAFADI_01711	1.86e-164	yndL	-	-	S	-	-	-	Replication protein
IPCAFADI_01712	4.12e-10	-	-	-	-	-	-	-	-
IPCAFADI_01713	6.02e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
IPCAFADI_01714	5.47e-87	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IPCAFADI_01716	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPCAFADI_01717	1.38e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IPCAFADI_01718	2.89e-142	yneB	-	-	L	-	-	-	resolvase
IPCAFADI_01719	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IPCAFADI_01720	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPCAFADI_01721	3.48e-103	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IPCAFADI_01722	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IPCAFADI_01723	8.06e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IPCAFADI_01724	9.68e-159	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IPCAFADI_01725	4.11e-75	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IPCAFADI_01726	6.24e-96	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IPCAFADI_01727	1.49e-92	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IPCAFADI_01728	3.21e-78	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IPCAFADI_01729	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IPCAFADI_01730	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IPCAFADI_01731	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPCAFADI_01732	6.2e-114	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPCAFADI_01733	2.66e-09	-	-	-	S	-	-	-	Fur-regulated basic protein B
IPCAFADI_01735	6.03e-45	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IPCAFADI_01736	8.11e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IPCAFADI_01737	2.43e-64	yneQ	-	-	-	-	-	-	-
IPCAFADI_01738	3.27e-58	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IPCAFADI_01739	1.51e-119	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPCAFADI_01740	5.75e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IPCAFADI_01741	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPCAFADI_01742	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPCAFADI_01743	2.21e-19	-	-	-	-	-	-	-	-
IPCAFADI_01744	7.12e-61	ynfC	-	-	-	-	-	-	-
IPCAFADI_01745	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IPCAFADI_01746	4.97e-34	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IPCAFADI_01747	1.71e-56	yndG	-	-	S	-	-	-	DoxX-like family
IPCAFADI_01748	2.44e-57	yndG	-	-	S	-	-	-	DoxX-like family
IPCAFADI_01749	1.54e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IPCAFADI_01750	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IPCAFADI_01751	8.6e-69	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
IPCAFADI_01752	3.33e-280	-	-	-	T	-	-	-	Histidine kinase
IPCAFADI_01753	6.43e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IPCAFADI_01754	3.32e-302	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
IPCAFADI_01755	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IPCAFADI_01756	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_01757	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_01758	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_01759	6.95e-265	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IPCAFADI_01760	6.26e-157	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IPCAFADI_01761	3.19e-136	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPCAFADI_01762	2.32e-145	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPCAFADI_01763	9.74e-211	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPCAFADI_01764	1.26e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPCAFADI_01765	2.47e-156	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPCAFADI_01766	5.39e-255	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPCAFADI_01767	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IPCAFADI_01768	7.35e-174	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IPCAFADI_01769	4.66e-85	yngA	-	-	S	-	-	-	membrane
IPCAFADI_01770	3.17e-167	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IPCAFADI_01771	6.22e-134	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_01772	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPCAFADI_01773	1.79e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IPCAFADI_01774	2.63e-209	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IPCAFADI_01775	6.54e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IPCAFADI_01776	2.17e-302	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IPCAFADI_01777	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPCAFADI_01778	5.12e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IPCAFADI_01779	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IPCAFADI_01780	3.25e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IPCAFADI_01781	3.97e-57	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
IPCAFADI_01782	6.69e-34	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_01783	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IPCAFADI_01784	3.68e-228	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IPCAFADI_01785	7.94e-307	yoeA	-	-	V	-	-	-	MATE efflux family protein
IPCAFADI_01786	1.38e-120	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IPCAFADI_01788	2.21e-122	-	-	-	L	-	-	-	Integrase
IPCAFADI_01789	1.11e-45	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IPCAFADI_01790	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IPCAFADI_01791	3.29e-247	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
IPCAFADI_01792	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
IPCAFADI_01793	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPCAFADI_01794	3.82e-171	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01795	8.54e-222	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IPCAFADI_01796	1.13e-61	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IPCAFADI_01797	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IPCAFADI_01798	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IPCAFADI_01799	6.14e-204	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01800	8.27e-252	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPCAFADI_01801	7.36e-176	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCAFADI_01802	6.69e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IPCAFADI_01803	1.41e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_01804	5.87e-48	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPCAFADI_01805	1.12e-150	yoxB	-	-	-	-	-	-	-
IPCAFADI_01806	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Cell division protein FtsX
IPCAFADI_01807	2.24e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
IPCAFADI_01808	5.79e-164	-	-	-	T	-	-	-	Histidine kinase
IPCAFADI_01809	9.84e-265	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IPCAFADI_01810	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IPCAFADI_01811	2.3e-235	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCAFADI_01812	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCAFADI_01813	7.02e-33	yoaF	-	-	-	-	-	-	-
IPCAFADI_01817	5.01e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IPCAFADI_01818	1.26e-155	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IPCAFADI_01819	3.96e-108	yobS	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01820	4.25e-160	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPCAFADI_01821	1.06e-116	yobW	-	-	-	-	-	-	-
IPCAFADI_01822	1.28e-71	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IPCAFADI_01823	9.03e-153	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPCAFADI_01824	5.42e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IPCAFADI_01825	5.75e-171	-	-	-	J	-	-	-	Protein required for attachment to host cells
IPCAFADI_01826	3.63e-120	yocC	-	-	-	-	-	-	-
IPCAFADI_01827	5.07e-236	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IPCAFADI_01829	6.61e-157	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IPCAFADI_01830	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPCAFADI_01831	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCAFADI_01832	6.39e-79	yocK	-	-	T	-	-	-	general stress protein
IPCAFADI_01834	2.02e-12	yocN	-	-	-	-	-	-	-
IPCAFADI_01835	7.69e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPCAFADI_01836	1.13e-58	yozN	-	-	-	-	-	-	-
IPCAFADI_01837	1.83e-49	yocN	-	-	-	-	-	-	-
IPCAFADI_01838	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
IPCAFADI_01840	4.69e-43	yozC	-	-	-	-	-	-	-
IPCAFADI_01841	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPCAFADI_01842	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IPCAFADI_01843	5.12e-207	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IPCAFADI_01844	6.6e-295	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPCAFADI_01845	5.59e-207	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IPCAFADI_01846	4.57e-164	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IPCAFADI_01847	1.12e-257	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IPCAFADI_01848	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IPCAFADI_01849	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IPCAFADI_01850	4.9e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IPCAFADI_01851	4.56e-136	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPCAFADI_01852	1.01e-273	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPCAFADI_01853	2.4e-278	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IPCAFADI_01854	1.14e-135	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPCAFADI_01856	4.32e-297	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IPCAFADI_01857	2.96e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCAFADI_01858	3.71e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IPCAFADI_01859	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IPCAFADI_01860	3.66e-31	-	-	-	-	-	-	-	-
IPCAFADI_01861	6.41e-205	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IPCAFADI_01862	4.5e-102	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IPCAFADI_01864	3.82e-82	iolK	-	-	S	-	-	-	tautomerase
IPCAFADI_01865	1.93e-69	yodB	-	-	K	-	-	-	transcriptional
IPCAFADI_01866	5.26e-136	yodC	-	-	C	-	-	-	nitroreductase
IPCAFADI_01867	3.87e-137	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IPCAFADI_01868	5.32e-213	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPCAFADI_01869	1.62e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IPCAFADI_01870	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCAFADI_01871	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
IPCAFADI_01872	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPCAFADI_01873	1.54e-163	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_01874	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IPCAFADI_01875	7.07e-156	yodH	-	-	Q	-	-	-	Methyltransferase
IPCAFADI_01876	5.89e-35	yodI	-	-	-	-	-	-	-
IPCAFADI_01877	1.01e-188	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IPCAFADI_01878	4.29e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IPCAFADI_01880	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
IPCAFADI_01881	9.75e-130	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IPCAFADI_01882	1.97e-33	yozD	-	-	S	-	-	-	YozD-like protein
IPCAFADI_01884	2.05e-156	yodN	-	-	-	-	-	-	-
IPCAFADI_01885	8.41e-68	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_01886	2.87e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IPCAFADI_01887	1.11e-59	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IPCAFADI_01888	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IPCAFADI_01889	4.82e-180	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IPCAFADI_01890	2.78e-315	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IPCAFADI_01891	6.06e-156	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPCAFADI_01892	1.81e-156	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPCAFADI_01893	1.69e-296	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCAFADI_01895	2.79e-176	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IPCAFADI_01896	1.38e-287	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IPCAFADI_01897	4.04e-54	cgeC	-	-	-	ko:K06321	-	ko00000	-
IPCAFADI_01898	5.35e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
IPCAFADI_01899	4.54e-215	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IPCAFADI_01900	4.76e-268	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IPCAFADI_01901	5.78e-91	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IPCAFADI_01904	6.89e-150	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
IPCAFADI_01906	4.82e-21	-	-	-	S	-	-	-	Regulatory protein YrvL
IPCAFADI_01907	6.8e-263	yokA	-	-	L	-	-	-	Recombinase
IPCAFADI_01908	5.24e-129	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IPCAFADI_01909	8.62e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IPCAFADI_01910	7.78e-130	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPCAFADI_01911	1.42e-88	ypoP	-	-	K	-	-	-	transcriptional
IPCAFADI_01912	2.55e-122	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_01913	1.47e-166	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPCAFADI_01914	1.84e-130	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IPCAFADI_01915	8.65e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IPCAFADI_01916	4.75e-306	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPCAFADI_01917	5.36e-208	yplP	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01918	1.01e-140	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IPCAFADI_01919	2.32e-139	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPCAFADI_01920	1.05e-108	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPCAFADI_01921	2.53e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCAFADI_01922	5.98e-144	ypjP	-	-	S	-	-	-	YpjP-like protein
IPCAFADI_01923	1.36e-169	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IPCAFADI_01924	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IPCAFADI_01925	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IPCAFADI_01926	6.01e-199	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IPCAFADI_01927	9.13e-119	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IPCAFADI_01928	2.98e-108	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IPCAFADI_01929	1.28e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPCAFADI_01930	1.01e-272	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IPCAFADI_01931	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IPCAFADI_01932	4.27e-16	degR	-	-	-	-	-	-	-
IPCAFADI_01933	5.37e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IPCAFADI_01934	6.37e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
IPCAFADI_01935	8.19e-152	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IPCAFADI_01936	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IPCAFADI_01937	3.51e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IPCAFADI_01939	1.7e-203	ypcP	-	-	L	-	-	-	5'3' exonuclease
IPCAFADI_01940	2.08e-11	-	-	-	-	-	-	-	-
IPCAFADI_01941	8.59e-45	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IPCAFADI_01942	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IPCAFADI_01943	3.19e-111	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IPCAFADI_01944	6.32e-253	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IPCAFADI_01945	1.54e-93	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IPCAFADI_01946	1.36e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
IPCAFADI_01947	4.95e-13	-	-	-	L	-	-	-	Membrane
IPCAFADI_01948	3.9e-112	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IPCAFADI_01949	1.03e-72	-	-	-	-	-	-	-	-
IPCAFADI_01951	3.09e-84	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
IPCAFADI_01952	3.89e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
IPCAFADI_01953	1.69e-07	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
IPCAFADI_01955	5.43e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
IPCAFADI_01956	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
IPCAFADI_01957	3.24e-288	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IPCAFADI_01958	1.25e-130	-	-	-	S	-	-	-	Phage tail protein
IPCAFADI_01959	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
IPCAFADI_01960	6.29e-06	-	-	-	-	-	-	-	-
IPCAFADI_01961	1.69e-105	-	-	-	S	-	-	-	Phage tail tube protein
IPCAFADI_01963	2.69e-63	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPCAFADI_01964	1.34e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
IPCAFADI_01965	9.84e-51	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IPCAFADI_01966	1.4e-35	-	-	-	-	-	-	-	-
IPCAFADI_01967	2.25e-198	-	-	-	S	-	-	-	capsid protein
IPCAFADI_01968	1.68e-105	-	-	-	S	-	-	-	peptidase activity
IPCAFADI_01969	8.65e-217	-	-	-	S	-	-	-	Phage portal protein
IPCAFADI_01970	0.0	-	-	-	S	-	-	-	Terminase
IPCAFADI_01971	2.45e-100	-	-	-	L	-	-	-	phage terminase small subunit
IPCAFADI_01975	8.82e-25	-	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01977	1.74e-17	-	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_01979	6.85e-87	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IPCAFADI_01982	3.08e-28	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IPCAFADI_01984	1.31e-77	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IPCAFADI_01986	2.87e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IPCAFADI_01987	8.39e-100	yqaL	-	-	L	-	-	-	DnaD domain protein
IPCAFADI_01989	2.8e-77	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
IPCAFADI_01990	1.86e-126	-	-	-	-	-	-	-	-
IPCAFADI_01994	9.77e-112	-	-	-	-	-	-	-	-
IPCAFADI_01995	6.66e-91	-	-	-	S	-	-	-	DNA binding
IPCAFADI_01996	3.79e-45	-	-	-	-	-	-	-	-
IPCAFADI_01997	6.12e-08	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IPCAFADI_01998	1.63e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPCAFADI_01999	3.13e-176	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPCAFADI_02000	3.27e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
IPCAFADI_02001	1.24e-123	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPCAFADI_02002	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IPCAFADI_02003	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IPCAFADI_02005	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
IPCAFADI_02006	3.59e-272	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IPCAFADI_02007	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPCAFADI_02008	9e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IPCAFADI_02009	9.86e-43	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
IPCAFADI_02011	4.24e-288	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IPCAFADI_02012	3.84e-98	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IPCAFADI_02013	2.19e-31	-	-	-	-	-	-	-	-
IPCAFADI_02017	2.79e-47	-	-	-	-	-	-	-	-
IPCAFADI_02018	1.61e-98	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
IPCAFADI_02020	5.61e-12	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IPCAFADI_02022	7.96e-87	-	-	-	S	ko:K06362	-	ko00000,ko01000	Tetratricopeptide repeat
IPCAFADI_02023	4.49e-102	-	-	-	K	-	-	-	Helix-turn-helix domain
IPCAFADI_02024	1.83e-08	-	-	-	K	ko:K07727	-	ko00000,ko03000	Helix-turn-helix domain
IPCAFADI_02025	4.98e-13	-	-	-	S	-	-	-	YolD-like protein
IPCAFADI_02028	2.76e-218	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IPCAFADI_02029	6.82e-34	-	-	-	-	-	-	-	-
IPCAFADI_02030	2.36e-139	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_02031	2.16e-39	xhlB	-	-	S	-	-	-	SPP1 phage holin
IPCAFADI_02033	9.2e-08	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
IPCAFADI_02035	4.22e-89	-	-	-	-	-	-	-	-
IPCAFADI_02036	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
IPCAFADI_02037	3.09e-227	-	-	-	L	-	-	-	Prophage endopeptidase tail
IPCAFADI_02038	9.18e-135	-	-	-	S	-	-	-	Phage tail protein
IPCAFADI_02039	9.94e-125	-	-	-	D	-	-	-	Phage tail tape measure protein
IPCAFADI_02040	6.85e-36	-	-	-	-	-	-	-	-
IPCAFADI_02041	7.25e-104	-	-	-	N	-	-	-	phage major tail protein, phi13 family
IPCAFADI_02042	1.49e-27	-	-	-	-	-	-	-	-
IPCAFADI_02043	2.27e-07	-	-	-	S	-	-	-	Phage virion morphogenesis
IPCAFADI_02044	1.28e-43	-	-	-	S	-	-	-	Phage head-tail joining protein
IPCAFADI_02045	3.63e-22	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IPCAFADI_02046	2.58e-163	-	-	-	S	-	-	-	Phage capsid family
IPCAFADI_02047	1.65e-112	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IPCAFADI_02048	1.66e-151	-	-	-	S	-	-	-	Phage portal protein
IPCAFADI_02049	9.78e-287	-	-	-	L	-	-	-	Terminase
IPCAFADI_02050	2.98e-36	-	-	-	L	-	-	-	Phage terminase, small subunit
IPCAFADI_02060	9.96e-145	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCAFADI_02061	7.27e-222	-	-	-	M	-	-	-	Parallel beta-helix repeats
IPCAFADI_02062	2.79e-111	-	-	-	S	-	-	-	Pfam:DUF867
IPCAFADI_02066	1.14e-32	-	-	-	-	-	-	-	-
IPCAFADI_02079	4.6e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF5052)
IPCAFADI_02083	2.86e-236	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IPCAFADI_02085	7.13e-14	-	-	-	M	-	-	-	3D domain
IPCAFADI_02088	1.7e-29	-	-	-	-	-	-	-	-
IPCAFADI_02089	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPCAFADI_02090	6.01e-14	-	-	-	K	ko:K03086	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_02092	0.0	-	-	-	L	-	-	-	DNA primase activity
IPCAFADI_02094	2.2e-263	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
IPCAFADI_02101	1.65e-124	-	-	-	L	-	-	-	Calcineurin-like phosphoesterase superfamily domain
IPCAFADI_02103	8.5e-97	-	-	-	L	-	-	-	DNA recombination
IPCAFADI_02105	2.01e-100	-	-	-	L	ko:K03546	-	ko00000,ko03400	AAA domain
IPCAFADI_02107	1.2e-12	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPCAFADI_02108	1.07e-09	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
IPCAFADI_02109	1.14e-216	-	-	-	L	ko:K06400	-	ko00000	recombinase activity
IPCAFADI_02110	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IPCAFADI_02111	6.99e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IPCAFADI_02112	1.2e-82	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPCAFADI_02113	6.81e-71	yppG	-	-	S	-	-	-	YppG-like protein
IPCAFADI_02118	6.09e-225	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IPCAFADI_02119	8.49e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPCAFADI_02120	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPCAFADI_02121	1.8e-110	ypoC	-	-	-	-	-	-	-
IPCAFADI_02122	1.4e-155	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPCAFADI_02123	8.05e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IPCAFADI_02124	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IPCAFADI_02125	2.71e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IPCAFADI_02126	4.93e-98	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_02127	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IPCAFADI_02128	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IPCAFADI_02129	1.98e-83	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPCAFADI_02130	5.03e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPCAFADI_02131	1.62e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IPCAFADI_02132	4.11e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPCAFADI_02133	1.53e-266	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPCAFADI_02134	2.45e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IPCAFADI_02135	6.57e-163	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IPCAFADI_02136	3.58e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IPCAFADI_02137	9.38e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPCAFADI_02138	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IPCAFADI_02139	6.13e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_02140	1.4e-280	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IPCAFADI_02141	3.8e-178	ypjB	-	-	S	-	-	-	sporulation protein
IPCAFADI_02142	2.6e-117	ypjA	-	-	S	-	-	-	membrane
IPCAFADI_02143	9.48e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IPCAFADI_02144	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IPCAFADI_02145	2.27e-124	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IPCAFADI_02146	2.54e-96	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IPCAFADI_02147	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IPCAFADI_02148	1.33e-292	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPCAFADI_02149	3.25e-291	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPCAFADI_02150	1.62e-256	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IPCAFADI_02151	1.54e-250	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPCAFADI_02152	2.18e-175	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IPCAFADI_02153	2.16e-284	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IPCAFADI_02154	2.2e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IPCAFADI_02155	4.02e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IPCAFADI_02156	2.68e-201	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPCAFADI_02157	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPCAFADI_02158	2.32e-76	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IPCAFADI_02159	1.14e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPCAFADI_02160	3.26e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPCAFADI_02161	1.38e-178	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IPCAFADI_02162	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IPCAFADI_02163	1.88e-250	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IPCAFADI_02164	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPCAFADI_02165	2.68e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IPCAFADI_02166	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IPCAFADI_02167	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IPCAFADI_02168	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPCAFADI_02169	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IPCAFADI_02171	4.09e-165	yphF	-	-	-	-	-	-	-
IPCAFADI_02172	1.13e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IPCAFADI_02173	3.19e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IPCAFADI_02174	2.86e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IPCAFADI_02175	4.31e-127	yphA	-	-	-	-	-	-	-
IPCAFADI_02176	2.78e-12	-	-	-	S	-	-	-	YpzI-like protein
IPCAFADI_02177	2.88e-229	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPCAFADI_02178	2.72e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IPCAFADI_02179	6.49e-143	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IPCAFADI_02180	3.89e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IPCAFADI_02181	2.31e-72	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IPCAFADI_02182	3.15e-311	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IPCAFADI_02183	1.98e-199	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IPCAFADI_02184	1.94e-148	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IPCAFADI_02185	6.92e-235	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IPCAFADI_02186	7.37e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPCAFADI_02187	3.22e-135	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPCAFADI_02188	5.39e-179	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IPCAFADI_02189	3.73e-109	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IPCAFADI_02190	2.53e-109	ypbE	-	-	M	-	-	-	Lysin motif
IPCAFADI_02191	6.41e-124	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IPCAFADI_02192	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPCAFADI_02193	1.35e-240	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IPCAFADI_02194	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IPCAFADI_02195	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPCAFADI_02196	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCAFADI_02197	1.99e-217	rsiX	-	-	-	-	-	-	-
IPCAFADI_02198	3.09e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPCAFADI_02199	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_02200	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_02201	2.54e-251	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IPCAFADI_02202	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IPCAFADI_02203	1.02e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IPCAFADI_02204	2.88e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IPCAFADI_02205	7.39e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IPCAFADI_02206	8.83e-134	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IPCAFADI_02207	9.6e-268	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPCAFADI_02208	2.4e-106	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IPCAFADI_02209	1.3e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPCAFADI_02210	3.47e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPCAFADI_02212	2.06e-114	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IPCAFADI_02213	9.18e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCAFADI_02214	1.4e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IPCAFADI_02215	4.95e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPCAFADI_02216	6.32e-141	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IPCAFADI_02217	4.32e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPCAFADI_02218	3.2e-67	ypuD	-	-	-	-	-	-	-
IPCAFADI_02219	2.37e-124	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPCAFADI_02220	1.08e-100	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
IPCAFADI_02221	1.18e-103	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPCAFADI_02222	3.35e-194	ypuA	-	-	S	-	-	-	Secreted protein
IPCAFADI_02223	2.27e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPCAFADI_02224	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IPCAFADI_02225	6.21e-141	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IPCAFADI_02226	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IPCAFADI_02227	4.54e-241	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IPCAFADI_02228	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IPCAFADI_02229	9.01e-89	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IPCAFADI_02230	1.84e-140	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IPCAFADI_02231	2.77e-173	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_02232	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IPCAFADI_02233	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IPCAFADI_02234	2.27e-269	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPCAFADI_02235	8.69e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPCAFADI_02236	1.08e-288	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPCAFADI_02237	1.03e-209	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IPCAFADI_02238	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IPCAFADI_02239	3.08e-102	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IPCAFADI_02240	4.12e-141	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IPCAFADI_02241	9.64e-42	yqkK	-	-	-	-	-	-	-
IPCAFADI_02242	1.02e-32	-	-	-	-	-	-	-	-
IPCAFADI_02243	2.66e-306	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IPCAFADI_02244	2.79e-310	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IPCAFADI_02245	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IPCAFADI_02246	1.7e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IPCAFADI_02247	2.32e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02248	8.26e-271	yqxK	-	-	L	-	-	-	DNA helicase
IPCAFADI_02249	1.42e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IPCAFADI_02250	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IPCAFADI_02251	4.52e-209	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IPCAFADI_02252	3.06e-15	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
IPCAFADI_02253	1.84e-213	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IPCAFADI_02254	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IPCAFADI_02255	1.22e-76	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IPCAFADI_02256	2.86e-214	yqkA	-	-	K	-	-	-	GrpB protein
IPCAFADI_02257	3.84e-08	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IPCAFADI_02258	3.16e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IPCAFADI_02259	1.01e-293	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCAFADI_02260	4.38e-74	-	-	-	S	-	-	-	YolD-like protein
IPCAFADI_02262	2.84e-206	yueF	-	-	S	-	-	-	transporter activity
IPCAFADI_02264	3.01e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IPCAFADI_02265	1.31e-303	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IPCAFADI_02266	6.3e-176	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_02267	6.43e-213	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPCAFADI_02268	1.07e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCAFADI_02269	6.96e-206	-	-	-	K	-	-	-	LysR substrate binding domain
IPCAFADI_02270	2.95e-62	-	-	-	S	-	-	-	GlpM protein
IPCAFADI_02271	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IPCAFADI_02272	2.4e-184	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IPCAFADI_02273	4.44e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IPCAFADI_02274	1.79e-216	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPCAFADI_02275	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPCAFADI_02276	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPCAFADI_02277	1.97e-294	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCAFADI_02278	1.36e-36	yqzJ	-	-	-	-	-	-	-
IPCAFADI_02279	1.32e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPCAFADI_02280	5.04e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IPCAFADI_02281	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPCAFADI_02282	3.67e-93	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IPCAFADI_02284	2.4e-119	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_02285	8.48e-215	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IPCAFADI_02286	9.26e-160	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPCAFADI_02287	8.21e-139	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPCAFADI_02288	3.77e-171	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPCAFADI_02289	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IPCAFADI_02290	1.37e-215	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPCAFADI_02291	2.69e-265	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCAFADI_02292	1.15e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCAFADI_02293	1.15e-214	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCAFADI_02294	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCAFADI_02295	1.35e-260	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IPCAFADI_02296	5.27e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPCAFADI_02297	2.65e-192	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IPCAFADI_02298	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IPCAFADI_02299	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IPCAFADI_02300	2.12e-200	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPCAFADI_02301	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IPCAFADI_02302	9.85e-261	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPCAFADI_02303	1.05e-252	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IPCAFADI_02304	3.22e-186	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IPCAFADI_02305	1.41e-265	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IPCAFADI_02306	6.02e-163	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IPCAFADI_02307	2.75e-127	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IPCAFADI_02309	5.08e-119	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IPCAFADI_02310	1.83e-142	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
IPCAFADI_02312	1.3e-262	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IPCAFADI_02315	1.29e-261	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPCAFADI_02317	2.05e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IPCAFADI_02318	1.1e-297	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IPCAFADI_02319	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IPCAFADI_02320	1.03e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IPCAFADI_02321	4.65e-194	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IPCAFADI_02322	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPCAFADI_02323	2.05e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IPCAFADI_02324	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPCAFADI_02325	2.66e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPCAFADI_02326	2.51e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPCAFADI_02327	2.58e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPCAFADI_02328	5.53e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_02329	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IPCAFADI_02330	2.59e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPCAFADI_02331	2.38e-86	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IPCAFADI_02332	2.63e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IPCAFADI_02333	1.01e-128	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IPCAFADI_02334	5e-259	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IPCAFADI_02335	5.28e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IPCAFADI_02336	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IPCAFADI_02337	2.23e-108	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IPCAFADI_02338	3.08e-212	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IPCAFADI_02339	1.64e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IPCAFADI_02340	9.69e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPCAFADI_02341	1.66e-246	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IPCAFADI_02342	9.02e-115	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IPCAFADI_02343	2.25e-215	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IPCAFADI_02344	8.59e-80	yqhP	-	-	-	-	-	-	-
IPCAFADI_02345	2.51e-203	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IPCAFADI_02346	4.64e-96	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IPCAFADI_02347	1.78e-201	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IPCAFADI_02348	2.33e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IPCAFADI_02349	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPCAFADI_02350	4.55e-315	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPCAFADI_02351	1.33e-254	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IPCAFADI_02352	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPCAFADI_02353	8.42e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IPCAFADI_02354	1.3e-29	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IPCAFADI_02355	2.27e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IPCAFADI_02356	8.28e-178	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IPCAFADI_02357	1.1e-94	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IPCAFADI_02358	1.08e-145	yqxM	-	-	-	ko:K19433	-	ko00000	-
IPCAFADI_02359	3.28e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IPCAFADI_02360	1.65e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
IPCAFADI_02361	1.4e-73	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IPCAFADI_02362	9.51e-28	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IPCAFADI_02363	4.41e-91	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
IPCAFADI_02364	1.98e-54	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IPCAFADI_02365	5.79e-227	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IPCAFADI_02366	2.04e-253	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPCAFADI_02368	3.15e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IPCAFADI_02369	5.23e-295	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPCAFADI_02370	1.24e-175	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCAFADI_02372	3.05e-82	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IPCAFADI_02373	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IPCAFADI_02374	4.03e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IPCAFADI_02375	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IPCAFADI_02376	4.09e-63	dglA	-	-	S	-	-	-	Thiamine-binding protein
IPCAFADI_02377	5.01e-236	yqgU	-	-	-	-	-	-	-
IPCAFADI_02378	8.76e-262	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IPCAFADI_02379	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IPCAFADI_02380	1.87e-37	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IPCAFADI_02381	2.71e-271	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IPCAFADI_02382	9.3e-12	yqgO	-	-	-	-	-	-	-
IPCAFADI_02383	7.31e-118	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPCAFADI_02384	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IPCAFADI_02385	3.42e-68	yqzD	-	-	-	-	-	-	-
IPCAFADI_02386	1.62e-95	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPCAFADI_02387	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPCAFADI_02388	2.99e-179	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPCAFADI_02389	3.26e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IPCAFADI_02390	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IPCAFADI_02391	1.06e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IPCAFADI_02392	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IPCAFADI_02393	3.43e-282	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IPCAFADI_02394	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IPCAFADI_02395	7.59e-97	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IPCAFADI_02396	8.5e-165	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IPCAFADI_02397	8.45e-59	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IPCAFADI_02398	2.3e-255	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPCAFADI_02399	1.59e-78	yqfX	-	-	S	-	-	-	membrane
IPCAFADI_02400	3.23e-139	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IPCAFADI_02401	2.63e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IPCAFADI_02402	6.08e-196	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_02403	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IPCAFADI_02404	1.3e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPCAFADI_02405	2.47e-307	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPCAFADI_02406	8.84e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IPCAFADI_02407	9.69e-224	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPCAFADI_02408	2.97e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPCAFADI_02409	6.71e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IPCAFADI_02410	7.67e-80	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IPCAFADI_02411	8e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPCAFADI_02412	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPCAFADI_02413	4.54e-111	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IPCAFADI_02414	1.75e-188	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IPCAFADI_02415	3.41e-144	ccpN	-	-	K	-	-	-	CBS domain
IPCAFADI_02416	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IPCAFADI_02417	2.03e-220	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IPCAFADI_02418	2.31e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IPCAFADI_02419	6e-24	-	-	-	S	-	-	-	YqzL-like protein
IPCAFADI_02420	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPCAFADI_02421	2.73e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IPCAFADI_02422	6.17e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IPCAFADI_02423	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPCAFADI_02424	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IPCAFADI_02425	3.37e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IPCAFADI_02426	1.02e-275	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IPCAFADI_02427	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IPCAFADI_02428	5.48e-50	yqfB	-	-	-	-	-	-	-
IPCAFADI_02429	1.22e-186	yqfA	-	-	S	-	-	-	UPF0365 protein
IPCAFADI_02430	2.36e-289	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IPCAFADI_02431	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IPCAFADI_02432	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IPCAFADI_02433	4.9e-195	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IPCAFADI_02434	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IPCAFADI_02435	3.96e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPCAFADI_02436	2.2e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IPCAFADI_02437	1.35e-263	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPCAFADI_02438	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IPCAFADI_02439	7.27e-107	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPCAFADI_02440	3.05e-237	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPCAFADI_02441	4.54e-264	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IPCAFADI_02442	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPCAFADI_02443	2.88e-69	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IPCAFADI_02444	6.13e-278	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IPCAFADI_02445	9.8e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IPCAFADI_02446	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IPCAFADI_02447	2.37e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IPCAFADI_02448	7.73e-22	-	-	-	S	-	-	-	YqzM-like protein
IPCAFADI_02449	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IPCAFADI_02450	5.18e-134	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IPCAFADI_02451	2.54e-121	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IPCAFADI_02452	1.74e-185	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCAFADI_02453	4.47e-174	yqeM	-	-	Q	-	-	-	Methyltransferase
IPCAFADI_02454	2.22e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPCAFADI_02455	1.96e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IPCAFADI_02456	6.29e-135	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPCAFADI_02457	8.62e-59	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IPCAFADI_02458	3.03e-194	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPCAFADI_02459	1.08e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IPCAFADI_02460	7.28e-122	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IPCAFADI_02462	2.22e-173	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPCAFADI_02463	9.76e-173	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IPCAFADI_02464	3.82e-141	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_02465	9.76e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_02467	1.4e-247	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IPCAFADI_02468	1.17e-158	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_02469	5.31e-204	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
IPCAFADI_02470	1.86e-114	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IPCAFADI_02471	3.17e-127	yqaC	-	-	F	-	-	-	adenylate kinase activity
IPCAFADI_02472	9.01e-41	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_02473	9.22e-80	-	-	-	S	-	-	-	TraX protein
IPCAFADI_02474	1.37e-38	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCAFADI_02475	1.16e-108	yrdA	-	-	S	-	-	-	DinB family
IPCAFADI_02476	2.04e-178	supH	-	-	S	-	-	-	hydrolase
IPCAFADI_02477	3.38e-176	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IPCAFADI_02478	4.55e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IPCAFADI_02479	3.92e-219	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPCAFADI_02480	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_02481	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IPCAFADI_02482	3.21e-213	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
IPCAFADI_02483	1.31e-97	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPCAFADI_02484	3.47e-206	yybE	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02485	1.57e-264	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_02486	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IPCAFADI_02487	3.6e-125	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IPCAFADI_02488	1.88e-113	yrhH	-	-	Q	-	-	-	methyltransferase
IPCAFADI_02489	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IPCAFADI_02490	2.99e-178	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IPCAFADI_02491	8.89e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IPCAFADI_02493	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
IPCAFADI_02494	4.38e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPCAFADI_02495	9.51e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
IPCAFADI_02496	2.65e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPCAFADI_02497	2.01e-210	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IPCAFADI_02498	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPCAFADI_02499	3.7e-148	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IPCAFADI_02500	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IPCAFADI_02501	1.78e-117	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IPCAFADI_02502	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IPCAFADI_02503	5.41e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPCAFADI_02504	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IPCAFADI_02505	1.73e-308	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IPCAFADI_02506	5.18e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IPCAFADI_02507	7.15e-148	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IPCAFADI_02508	5.98e-245	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPCAFADI_02509	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IPCAFADI_02510	1.11e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPCAFADI_02511	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IPCAFADI_02512	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPCAFADI_02513	2.41e-223	yrrI	-	-	S	-	-	-	AI-2E family transporter
IPCAFADI_02514	3.37e-163	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPCAFADI_02515	5.82e-185	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPCAFADI_02516	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPCAFADI_02517	3.61e-137	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPCAFADI_02518	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IPCAFADI_02519	8.4e-42	yrzR	-	-	-	-	-	-	-
IPCAFADI_02520	1.82e-100	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_02521	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPCAFADI_02522	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPCAFADI_02523	1.62e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPCAFADI_02524	4.54e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPCAFADI_02525	3.74e-83	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_02526	1.03e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IPCAFADI_02527	9.74e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IPCAFADI_02528	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPCAFADI_02529	1.07e-303	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IPCAFADI_02532	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IPCAFADI_02533	4.07e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPCAFADI_02534	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPCAFADI_02535	1.71e-116	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPCAFADI_02536	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IPCAFADI_02537	6.15e-60	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IPCAFADI_02538	3.34e-107	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IPCAFADI_02539	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPCAFADI_02540	1.65e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IPCAFADI_02541	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_02542	1.92e-132	yrbG	-	-	S	-	-	-	membrane
IPCAFADI_02543	3.7e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IPCAFADI_02544	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IPCAFADI_02545	3.9e-291	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPCAFADI_02546	5.55e-244	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPCAFADI_02547	6.87e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IPCAFADI_02548	1.9e-231	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPCAFADI_02549	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPCAFADI_02550	1.16e-118	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IPCAFADI_02552	5.11e-60	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCAFADI_02553	4.67e-224	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IPCAFADI_02554	6.21e-265	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPCAFADI_02555	1.58e-181	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IPCAFADI_02556	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IPCAFADI_02557	4.96e-270	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPCAFADI_02558	6.31e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IPCAFADI_02559	3.06e-201	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IPCAFADI_02560	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IPCAFADI_02561	5.83e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPCAFADI_02562	2.87e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IPCAFADI_02563	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IPCAFADI_02564	5.78e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IPCAFADI_02565	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IPCAFADI_02566	1.83e-199	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IPCAFADI_02567	7.6e-177	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IPCAFADI_02568	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IPCAFADI_02569	3.74e-143	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IPCAFADI_02570	2.3e-106	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IPCAFADI_02571	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IPCAFADI_02572	2.91e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IPCAFADI_02573	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IPCAFADI_02574	3.77e-127	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IPCAFADI_02575	7.2e-192	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IPCAFADI_02576	5.7e-159	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IPCAFADI_02577	1.76e-296	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IPCAFADI_02578	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPCAFADI_02579	3.61e-34	-	-	-	-	-	-	-	-
IPCAFADI_02580	2.72e-235	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IPCAFADI_02581	3.75e-224	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IPCAFADI_02582	1.66e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IPCAFADI_02583	1.7e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IPCAFADI_02584	1.43e-175	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IPCAFADI_02585	2.11e-222	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IPCAFADI_02586	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IPCAFADI_02587	3.97e-311	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPCAFADI_02588	4.24e-109	ysxD	-	-	-	-	-	-	-
IPCAFADI_02589	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IPCAFADI_02590	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPCAFADI_02591	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IPCAFADI_02592	1.56e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPCAFADI_02593	1.79e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPCAFADI_02594	8.77e-237	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IPCAFADI_02595	1.26e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPCAFADI_02596	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPCAFADI_02597	6.53e-250	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IPCAFADI_02598	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPCAFADI_02599	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPCAFADI_02600	1.45e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IPCAFADI_02601	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IPCAFADI_02606	5.31e-115	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IPCAFADI_02607	3.07e-129	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPCAFADI_02608	1.18e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPCAFADI_02609	1.05e-253	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IPCAFADI_02610	1.29e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IPCAFADI_02611	1.26e-95	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPCAFADI_02612	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_02613	8.26e-96	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IPCAFADI_02614	1.77e-188	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IPCAFADI_02615	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IPCAFADI_02616	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IPCAFADI_02617	9.97e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IPCAFADI_02618	2.64e-269	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPCAFADI_02619	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPCAFADI_02620	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IPCAFADI_02621	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IPCAFADI_02622	4.79e-225	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IPCAFADI_02623	2.37e-175	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IPCAFADI_02624	2.97e-170	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IPCAFADI_02625	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_02626	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPCAFADI_02627	1.73e-145	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IPCAFADI_02628	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IPCAFADI_02629	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPCAFADI_02630	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IPCAFADI_02631	3.5e-108	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IPCAFADI_02632	4.23e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IPCAFADI_02633	1.71e-212	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPCAFADI_02634	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPCAFADI_02635	5.16e-248	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPCAFADI_02636	2.88e-167	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPCAFADI_02637	8.83e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IPCAFADI_02638	2.6e-241	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IPCAFADI_02639	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
IPCAFADI_02640	7.74e-313	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IPCAFADI_02641	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IPCAFADI_02642	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IPCAFADI_02643	1.27e-186	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IPCAFADI_02644	8.11e-211	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IPCAFADI_02645	1.62e-313	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IPCAFADI_02646	1.25e-264	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IPCAFADI_02647	3.14e-174	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IPCAFADI_02648	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IPCAFADI_02649	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IPCAFADI_02650	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IPCAFADI_02651	8.75e-235	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IPCAFADI_02652	1.25e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IPCAFADI_02653	4.11e-82	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IPCAFADI_02654	6.14e-53	ysdA	-	-	S	-	-	-	Membrane
IPCAFADI_02655	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPCAFADI_02656	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IPCAFADI_02657	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPCAFADI_02658	1.21e-144	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IPCAFADI_02659	4.53e-66	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
IPCAFADI_02660	8.26e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IPCAFADI_02661	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_02662	2.6e-187	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IPCAFADI_02663	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPCAFADI_02664	7.14e-191	ytxC	-	-	S	-	-	-	YtxC-like family
IPCAFADI_02665	8.26e-136	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IPCAFADI_02666	2.64e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IPCAFADI_02667	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IPCAFADI_02668	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPCAFADI_02669	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IPCAFADI_02670	4.24e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPCAFADI_02671	7.74e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02672	2.84e-252	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IPCAFADI_02673	5.7e-199	ytbE	-	-	S	-	-	-	reductase
IPCAFADI_02674	2.13e-121	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPCAFADI_02675	4.52e-135	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IPCAFADI_02676	1.51e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPCAFADI_02677	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPCAFADI_02678	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IPCAFADI_02679	5.62e-165	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_02680	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IPCAFADI_02681	6.26e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IPCAFADI_02682	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPCAFADI_02683	1.92e-96	ytwI	-	-	S	-	-	-	membrane
IPCAFADI_02684	1.16e-246	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IPCAFADI_02685	1.34e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IPCAFADI_02686	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IPCAFADI_02687	1.09e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IPCAFADI_02688	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IPCAFADI_02689	2.08e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPCAFADI_02690	4.72e-284	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IPCAFADI_02691	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IPCAFADI_02692	9.6e-73	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IPCAFADI_02693	1.08e-113	ytrI	-	-	-	-	-	-	-
IPCAFADI_02694	8.25e-31	-	-	-	-	-	-	-	-
IPCAFADI_02695	4.26e-222	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IPCAFADI_02696	3.57e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
IPCAFADI_02697	3.91e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IPCAFADI_02698	1.15e-163	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IPCAFADI_02699	5.43e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_02701	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IPCAFADI_02702	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPCAFADI_02703	1.64e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IPCAFADI_02704	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPCAFADI_02705	3.5e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IPCAFADI_02706	9.21e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPCAFADI_02707	1.37e-99	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IPCAFADI_02708	5.13e-147	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IPCAFADI_02709	2.87e-107	yteJ	-	-	S	-	-	-	RDD family
IPCAFADI_02710	6.56e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IPCAFADI_02711	8.69e-192	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPCAFADI_02712	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IPCAFADI_02713	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPCAFADI_02714	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
IPCAFADI_02715	1.51e-280	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPCAFADI_02716	1.39e-259	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPCAFADI_02717	3.1e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IPCAFADI_02718	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPCAFADI_02719	1.61e-184	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IPCAFADI_02720	4.67e-139	yttP	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02721	1.18e-109	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IPCAFADI_02722	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IPCAFADI_02723	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPCAFADI_02724	3.66e-274	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPCAFADI_02728	1.25e-160	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IPCAFADI_02729	9.24e-189	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCAFADI_02730	3.69e-189	-	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02731	6.18e-155	ygaZ	-	-	E	-	-	-	AzlC protein
IPCAFADI_02732	2.07e-62	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
IPCAFADI_02733	7.49e-300	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPCAFADI_02734	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPCAFADI_02735	9.52e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IPCAFADI_02736	3.53e-142	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IPCAFADI_02737	8.11e-283	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IPCAFADI_02738	1.21e-145	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IPCAFADI_02739	1.23e-184	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IPCAFADI_02740	7.39e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IPCAFADI_02741	5.16e-248	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IPCAFADI_02742	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IPCAFADI_02743	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IPCAFADI_02744	2.16e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPCAFADI_02745	9.62e-317	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IPCAFADI_02746	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IPCAFADI_02747	6.96e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPCAFADI_02748	7.71e-187	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IPCAFADI_02749	1.51e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
IPCAFADI_02750	5.33e-98	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IPCAFADI_02751	2.06e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IPCAFADI_02752	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
IPCAFADI_02753	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IPCAFADI_02754	1.21e-205	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPCAFADI_02755	1.3e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPCAFADI_02756	4.54e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
IPCAFADI_02757	3.42e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
IPCAFADI_02758	5.32e-214	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IPCAFADI_02759	2e-182	ytlQ	-	-	-	-	-	-	-
IPCAFADI_02760	3.53e-129	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IPCAFADI_02761	1.16e-213	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IPCAFADI_02762	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IPCAFADI_02763	3.89e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IPCAFADI_02764	2.1e-252	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IPCAFADI_02765	2.73e-149	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IPCAFADI_02766	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IPCAFADI_02767	7.35e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IPCAFADI_02768	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_02769	4.66e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IPCAFADI_02770	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IPCAFADI_02771	3.57e-35	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IPCAFADI_02772	1.09e-229	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_02773	5.91e-297	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IPCAFADI_02774	1.41e-211	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPCAFADI_02775	6.79e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IPCAFADI_02776	3.54e-313	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IPCAFADI_02777	1.22e-93	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
IPCAFADI_02778	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IPCAFADI_02779	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IPCAFADI_02780	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IPCAFADI_02781	6.25e-173	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IPCAFADI_02782	8.8e-265	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IPCAFADI_02783	8.43e-151	ywaF	-	-	S	-	-	-	Integral membrane protein
IPCAFADI_02784	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IPCAFADI_02785	3.65e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_02786	2.24e-208	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IPCAFADI_02787	3.13e-158	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_02788	2.14e-259	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IPCAFADI_02789	2.88e-159	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_02790	3.11e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IPCAFADI_02791	1.46e-202	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPCAFADI_02792	3.53e-212	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPCAFADI_02793	9.08e-202	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_02794	6.32e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IPCAFADI_02796	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IPCAFADI_02797	3.89e-243	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IPCAFADI_02798	1.66e-132	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IPCAFADI_02800	2.91e-168	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
IPCAFADI_02801	2.17e-266	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IPCAFADI_02802	9.48e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IPCAFADI_02803	7.46e-80	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IPCAFADI_02804	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_02805	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IPCAFADI_02806	3.21e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPCAFADI_02807	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IPCAFADI_02808	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IPCAFADI_02809	1.02e-185	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IPCAFADI_02810	2.47e-227	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IPCAFADI_02811	1.38e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPCAFADI_02812	3.42e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IPCAFADI_02813	5.86e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IPCAFADI_02814	1.67e-77	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IPCAFADI_02815	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IPCAFADI_02817	9.99e-98	ytkA	-	-	S	-	-	-	YtkA-like
IPCAFADI_02818	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPCAFADI_02819	4.02e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IPCAFADI_02820	2.02e-131	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IPCAFADI_02821	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IPCAFADI_02822	9.03e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IPCAFADI_02823	1.44e-232	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IPCAFADI_02824	2.84e-33	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IPCAFADI_02825	2.08e-265	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IPCAFADI_02826	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IPCAFADI_02827	2.07e-197	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IPCAFADI_02828	3.54e-190	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IPCAFADI_02829	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IPCAFADI_02830	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IPCAFADI_02831	8.57e-160	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IPCAFADI_02832	3.36e-93	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IPCAFADI_02854	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPCAFADI_02855	3.55e-118	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IPCAFADI_02856	3.23e-272	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IPCAFADI_02857	1.48e-104	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IPCAFADI_02858	1.17e-101	yuaE	-	-	S	-	-	-	DinB superfamily
IPCAFADI_02859	1.42e-133	-	-	-	S	-	-	-	MOSC domain
IPCAFADI_02860	9.64e-288	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IPCAFADI_02861	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPCAFADI_02862	4.78e-119	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IPCAFADI_02863	2.28e-119	yuaB	-	-	-	-	-	-	-
IPCAFADI_02864	7.16e-155	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IPCAFADI_02865	5.57e-186	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPCAFADI_02866	1.13e-270	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPCAFADI_02867	1.69e-144	-	-	-	G	-	-	-	Cupin
IPCAFADI_02868	1.78e-58	yjcN	-	-	-	-	-	-	-
IPCAFADI_02869	1.89e-127	-	-	-	K	-	-	-	Helix-turn-helix domain
IPCAFADI_02870	1.12e-06	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IPCAFADI_02871	2.19e-14	-	-	-	S	-	-	-	YolD-like protein
IPCAFADI_02873	5.17e-46	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
IPCAFADI_02874	6.73e-184	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IPCAFADI_02875	2.35e-39	-	-	-	S	-	-	-	BhlA holin family
IPCAFADI_02878	1.69e-109	-	-	-	-	-	-	-	-
IPCAFADI_02879	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
IPCAFADI_02880	1.18e-94	-	-	-	L	-	-	-	Prophage endopeptidase tail
IPCAFADI_02881	1.31e-69	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IPCAFADI_02882	3.47e-201	-	-	-	D	-	-	-	phage tail tape measure protein
IPCAFADI_02884	2.97e-31	-	-	-	-	-	-	-	-
IPCAFADI_02885	2.68e-60	-	-	-	N	-	-	-	domain, Protein
IPCAFADI_02886	6.28e-26	-	-	-	-	-	-	-	-
IPCAFADI_02889	1.74e-36	-	-	-	-	-	-	-	-
IPCAFADI_02892	1.12e-188	-	-	-	S	-	-	-	Family of unknown function (DUF5309)
IPCAFADI_02893	9.44e-36	-	-	-	-	-	-	-	-
IPCAFADI_02894	9.59e-100	-	-	-	S	-	-	-	Phage minor capsid protein 2
IPCAFADI_02895	1.83e-201	-	-	-	-	-	-	-	-
IPCAFADI_02896	4.66e-37	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
IPCAFADI_02897	0.0	-	-	-	S	-	-	-	TIGRFAM Phage
IPCAFADI_02898	7.88e-87	-	-	-	L	-	-	-	Phage integrase family
IPCAFADI_02901	3e-51	-	-	GT2	S	ko:K19425,ko:K19427	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_02902	2.71e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IPCAFADI_02903	1.69e-72	-	-	-	S	-	-	-	Pfam:DUF867
IPCAFADI_02904	2.6e-141	-	-	-	M	-	-	-	Right handed beta helix region
IPCAFADI_02907	5.18e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2786)
IPCAFADI_02909	7.61e-32	-	-	-	-	-	-	-	-
IPCAFADI_02911	7.33e-151	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
IPCAFADI_02913	3.2e-173	-	-	-	-	-	-	-	-
IPCAFADI_02914	2.1e-63	-	-	-	-	-	-	-	-
IPCAFADI_02915	7.74e-62	-	-	-	K	-	-	-	Sigma-70, region 4
IPCAFADI_02917	6.59e-85	-	-	-	H	-	-	-	dephospho-CoA kinase activity
IPCAFADI_02918	1.07e-45	-	-	-	-	-	-	-	-
IPCAFADI_02919	1.29e-65	ybiA	-	-	O	ko:K09935	-	ko00000	Protein conserved in bacteria
IPCAFADI_02920	1.34e-47	-	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_02921	4.17e-142	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCAFADI_02923	1.49e-74	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
IPCAFADI_02925	1.41e-190	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCAFADI_02927	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCAFADI_02928	4.2e-79	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IPCAFADI_02929	2.75e-56	-	-	-	F	-	-	-	Belongs to the NrdI family
IPCAFADI_02934	8.87e-22	-	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Crossover junction endodeoxyribonuclease RuvC
IPCAFADI_02936	2.39e-206	-	-	-	-	-	-	-	-
IPCAFADI_02937	4.17e-132	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
IPCAFADI_02938	9.92e-98	-	-	-	S	-	-	-	RNA ligase
IPCAFADI_02939	1.75e-247	-	-	-	L	-	-	-	3'-5' exonuclease
IPCAFADI_02941	7.2e-33	-	-	-	-	-	-	-	-
IPCAFADI_02943	3.74e-64	-	-	-	-	-	-	-	-
IPCAFADI_02944	3.75e-121	-	-	-	-	-	-	-	-
IPCAFADI_02951	3.02e-168	-	-	-	L	-	-	-	Toprim-like
IPCAFADI_02952	3.03e-174	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
IPCAFADI_02955	3.12e-139	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
IPCAFADI_02957	6.8e-68	-	-	-	-	-	-	-	-
IPCAFADI_02959	2.46e-22	-	-	-	-	-	-	-	-
IPCAFADI_02964	2.33e-46	-	-	-	-	-	-	-	-
IPCAFADI_02967	5.51e-109	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IPCAFADI_02969	7.33e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IPCAFADI_02970	2.73e-248	yubA	-	-	S	-	-	-	transporter activity
IPCAFADI_02971	1.39e-230	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IPCAFADI_02972	4.02e-126	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IPCAFADI_02973	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPCAFADI_02974	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPCAFADI_02975	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPCAFADI_02976	1.82e-284	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPCAFADI_02977	4.12e-175	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IPCAFADI_02978	1.82e-52	-	-	-	-	-	-	-	-
IPCAFADI_02979	1.84e-238	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IPCAFADI_02980	5.67e-96	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
IPCAFADI_02981	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPCAFADI_02982	1.82e-293	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPCAFADI_02983	1.18e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IPCAFADI_02984	7.54e-24	-	-	-	-	-	-	-	-
IPCAFADI_02985	8.53e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IPCAFADI_02986	3e-225	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IPCAFADI_02987	2.65e-89	yugN	-	-	S	-	-	-	YugN-like family
IPCAFADI_02989	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IPCAFADI_02990	8.63e-20	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
IPCAFADI_02991	1.67e-89	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
IPCAFADI_02992	2.93e-150	ycaC	-	-	Q	-	-	-	Isochorismatase family
IPCAFADI_02993	3.6e-287	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IPCAFADI_02994	1.07e-282	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IPCAFADI_02995	1.28e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IPCAFADI_02996	8.3e-82	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IPCAFADI_02997	7.62e-263	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IPCAFADI_02998	1.53e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_02999	1.14e-190	yugF	-	-	I	-	-	-	Hydrolase
IPCAFADI_03000	3.95e-51	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IPCAFADI_03001	1.1e-275	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IPCAFADI_03002	4.86e-281	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03003	3.54e-82	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IPCAFADI_03004	8.87e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IPCAFADI_03005	7.46e-240	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IPCAFADI_03006	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IPCAFADI_03007	5.95e-92	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03008	4.19e-97	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IPCAFADI_03009	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPCAFADI_03010	2.68e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IPCAFADI_03011	1.94e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IPCAFADI_03012	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_03013	5.86e-233	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPCAFADI_03014	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPCAFADI_03016	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IPCAFADI_03017	1.81e-89	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCAFADI_03018	1.42e-65	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCAFADI_03019	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCAFADI_03020	3.78e-96	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCAFADI_03021	1.84e-50	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCAFADI_03022	6.71e-76	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IPCAFADI_03023	3.55e-77	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IPCAFADI_03024	3.29e-147	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCAFADI_03025	9.02e-298	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03027	3.98e-82	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IPCAFADI_03028	1.87e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
IPCAFADI_03029	9.2e-62	yuzC	-	-	-	-	-	-	-
IPCAFADI_03030	5.31e-284	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IPCAFADI_03031	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPCAFADI_03032	1.05e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IPCAFADI_03033	4.96e-86	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IPCAFADI_03034	1.1e-50	yueH	-	-	S	-	-	-	YueH-like protein
IPCAFADI_03035	4.3e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IPCAFADI_03036	1.88e-229	yueF	-	-	S	-	-	-	transporter activity
IPCAFADI_03037	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IPCAFADI_03038	3.7e-123	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IPCAFADI_03039	4.24e-162	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_03040	3e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IPCAFADI_03041	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IPCAFADI_03042	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IPCAFADI_03043	1.32e-253	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IPCAFADI_03044	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IPCAFADI_03045	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IPCAFADI_03046	6.77e-288	yukF	-	-	QT	-	-	-	Transcriptional regulator
IPCAFADI_03047	7.76e-259	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IPCAFADI_03048	2.71e-165	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IPCAFADI_03049	2.97e-41	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IPCAFADI_03050	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_03051	1.92e-211	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IPCAFADI_03052	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IPCAFADI_03053	5.21e-275	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IPCAFADI_03054	2.17e-165	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_03055	9.01e-196	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IPCAFADI_03056	3.49e-150	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IPCAFADI_03057	7.21e-129	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IPCAFADI_03058	1.11e-273	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IPCAFADI_03059	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPCAFADI_03060	9.67e-99	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IPCAFADI_03061	2.23e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03062	1.21e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
IPCAFADI_03063	3.83e-297	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPCAFADI_03064	1.15e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IPCAFADI_03066	5.04e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPCAFADI_03067	4.93e-166	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_03068	1.88e-80	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IPCAFADI_03069	8.81e-205	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPCAFADI_03070	3.64e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCAFADI_03071	4.81e-50	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IPCAFADI_03072	6.4e-261	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPCAFADI_03073	7.47e-70	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03074	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IPCAFADI_03075	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IPCAFADI_03076	7.43e-205	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IPCAFADI_03077	5.18e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPCAFADI_03078	5.57e-306	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IPCAFADI_03079	1.94e-244	yutH	-	-	S	-	-	-	Spore coat protein
IPCAFADI_03080	6.22e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IPCAFADI_03081	1.18e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPCAFADI_03082	3e-93	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IPCAFADI_03083	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03084	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPCAFADI_03085	1.26e-245	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IPCAFADI_03086	1.53e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IPCAFADI_03087	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IPCAFADI_03088	1.6e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPCAFADI_03089	1.66e-213	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IPCAFADI_03090	1.1e-73	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
IPCAFADI_03091	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IPCAFADI_03092	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IPCAFADI_03095	1.58e-78	-	-	-	-	-	-	-	-
IPCAFADI_03096	1.25e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_03097	2.78e-291	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IPCAFADI_03098	2.96e-284	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IPCAFADI_03099	3.33e-209	bsn	-	-	L	-	-	-	Ribonuclease
IPCAFADI_03100	1.17e-249	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_03101	1.14e-170	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IPCAFADI_03102	2.71e-199	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IPCAFADI_03103	7.15e-200	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IPCAFADI_03104	7.16e-201	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPCAFADI_03105	1.6e-307	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IPCAFADI_03106	1.02e-232	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IPCAFADI_03107	9.35e-203	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IPCAFADI_03109	9.46e-96	-	-	-	-	-	-	-	-
IPCAFADI_03110	4.94e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IPCAFADI_03112	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IPCAFADI_03113	3.25e-253	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IPCAFADI_03114	1.34e-150	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IPCAFADI_03115	5.88e-93	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
IPCAFADI_03116	3.54e-192	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IPCAFADI_03117	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
IPCAFADI_03118	7.15e-125	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	PFAM Type I restriction modification DNA specificity domain
IPCAFADI_03119	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IPCAFADI_03120	4.1e-102	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IPCAFADI_03122	1.16e-08	int	-	-	L	-	-	-	Phage integrase family
IPCAFADI_03123	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IPCAFADI_03124	4.95e-98	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IPCAFADI_03125	3.67e-295	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPCAFADI_03126	1.75e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IPCAFADI_03127	1.1e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IPCAFADI_03128	2.54e-84	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPCAFADI_03129	1.17e-182	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IPCAFADI_03130	1.15e-135	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IPCAFADI_03131	8.74e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPCAFADI_03132	5.08e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IPCAFADI_03133	2.25e-70	yusE	-	-	CO	-	-	-	Thioredoxin
IPCAFADI_03134	6.99e-79	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IPCAFADI_03135	2.99e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IPCAFADI_03136	1.19e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IPCAFADI_03137	2.91e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IPCAFADI_03138	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IPCAFADI_03139	8.65e-275	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IPCAFADI_03140	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IPCAFADI_03141	1.72e-10	-	-	-	S	-	-	-	YuzL-like protein
IPCAFADI_03142	1.24e-204	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IPCAFADI_03143	2.88e-266	yusP	-	-	P	-	-	-	Major facilitator superfamily
IPCAFADI_03144	1.47e-54	-	-	-	-	-	-	-	-
IPCAFADI_03145	4.29e-70	yusN	-	-	M	-	-	-	Coat F domain
IPCAFADI_03146	5.26e-94	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IPCAFADI_03147	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IPCAFADI_03148	1.46e-50	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IPCAFADI_03149	5.24e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPCAFADI_03150	1.13e-61	-	-	-	S	-	-	-	YusW-like protein
IPCAFADI_03151	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IPCAFADI_03152	6.16e-178	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_03153	1.61e-100	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IPCAFADI_03154	1.05e-295	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCAFADI_03155	2.5e-161	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_03156	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03157	2.68e-32	-	-	-	-	-	-	-	-
IPCAFADI_03158	5.5e-195	yuxN	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03159	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPCAFADI_03160	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IPCAFADI_03161	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPCAFADI_03162	1.17e-232	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IPCAFADI_03163	3.22e-248	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IPCAFADI_03164	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCAFADI_03165	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03166	6.45e-157	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IPCAFADI_03167	8.92e-164	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IPCAFADI_03168	1.64e-125	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IPCAFADI_03169	1.22e-63	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IPCAFADI_03170	1.91e-280	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_03171	3.89e-125	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IPCAFADI_03172	5.35e-257	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IPCAFADI_03173	1.64e-223	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_03174	1.3e-212	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPCAFADI_03175	2.89e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_03176	5.79e-214	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IPCAFADI_03177	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IPCAFADI_03178	1.56e-171	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_03179	1.14e-48	-	-	-	-	-	-	-	-
IPCAFADI_03180	3.1e-132	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IPCAFADI_03181	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
IPCAFADI_03182	4.24e-293	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IPCAFADI_03183	9.67e-79	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IPCAFADI_03184	1.62e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPCAFADI_03185	4.01e-218	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_03186	6.08e-234	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_03187	1.5e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPCAFADI_03188	5.33e-154	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IPCAFADI_03189	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IPCAFADI_03190	4.34e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IPCAFADI_03191	4.11e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IPCAFADI_03192	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IPCAFADI_03193	3.41e-205	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IPCAFADI_03194	3.47e-174	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IPCAFADI_03195	8.36e-118	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IPCAFADI_03196	1.69e-145	yfiK	-	-	K	-	-	-	Regulator
IPCAFADI_03197	7.53e-231	-	-	-	T	-	-	-	Histidine kinase
IPCAFADI_03198	1.36e-217	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IPCAFADI_03199	2.57e-235	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IPCAFADI_03200	1.25e-246	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IPCAFADI_03201	1.15e-196	yvgN	-	-	S	-	-	-	reductase
IPCAFADI_03202	6.3e-110	yvgO	-	-	-	-	-	-	-
IPCAFADI_03203	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IPCAFADI_03204	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IPCAFADI_03205	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IPCAFADI_03206	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPCAFADI_03207	1.82e-129	yvgT	-	-	S	-	-	-	membrane
IPCAFADI_03208	8.69e-187	-	-	-	S	-	-	-	Metallo-peptidase family M12
IPCAFADI_03209	2.51e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IPCAFADI_03210	4.15e-134	bdbD	-	-	O	-	-	-	Thioredoxin
IPCAFADI_03211	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IPCAFADI_03212	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IPCAFADI_03213	3.12e-38	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
IPCAFADI_03214	2.05e-61	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IPCAFADI_03215	5.71e-239	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IPCAFADI_03216	1.46e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCAFADI_03217	9.4e-317	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_03218	6.35e-56	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
IPCAFADI_03219	7.83e-220	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_03220	7.09e-178	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPCAFADI_03221	2.17e-151	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPCAFADI_03222	2.61e-150	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPCAFADI_03223	1.09e-182	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IPCAFADI_03224	4.27e-163	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IPCAFADI_03225	3.04e-126	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IPCAFADI_03226	3.97e-204	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
IPCAFADI_03227	1.37e-178	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCAFADI_03228	1.24e-58	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IPCAFADI_03229	7.3e-73	-	-	-	-	-	-	-	-
IPCAFADI_03232	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPCAFADI_03233	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPCAFADI_03234	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IPCAFADI_03235	9.24e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IPCAFADI_03236	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
IPCAFADI_03237	1.07e-89	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IPCAFADI_03238	1.09e-90	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IPCAFADI_03239	1.17e-67	yvaP	-	-	K	-	-	-	transcriptional
IPCAFADI_03240	5.45e-312	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IPCAFADI_03241	7.17e-154	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IPCAFADI_03242	3.43e-163	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPCAFADI_03243	9.08e-153	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPCAFADI_03244	4.96e-158	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_03245	8.16e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCAFADI_03246	6.2e-211	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPCAFADI_03247	6.04e-140	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCAFADI_03248	1.25e-262	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPCAFADI_03249	8e-114	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IPCAFADI_03250	2.42e-138	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCAFADI_03251	1.73e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPCAFADI_03252	5.4e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCAFADI_03253	3.48e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPCAFADI_03254	1.61e-126	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IPCAFADI_03255	1.55e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IPCAFADI_03256	3.88e-150	yvbI	-	-	M	-	-	-	Membrane
IPCAFADI_03257	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IPCAFADI_03258	8.76e-104	yvbK	-	-	K	-	-	-	acetyltransferase
IPCAFADI_03259	4.16e-260	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IPCAFADI_03260	3.23e-220	-	-	-	-	-	-	-	-
IPCAFADI_03261	3.54e-159	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
IPCAFADI_03262	9.29e-182	-	-	-	C	-	-	-	WbqC-like protein family
IPCAFADI_03263	3.53e-179	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
IPCAFADI_03264	1.9e-278	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPCAFADI_03265	3.75e-214	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
IPCAFADI_03266	8.59e-272	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IPCAFADI_03267	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPCAFADI_03268	6.94e-287	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IPCAFADI_03269	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPCAFADI_03270	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IPCAFADI_03271	1.49e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPCAFADI_03272	2.57e-273	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IPCAFADI_03273	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPCAFADI_03274	1.15e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPCAFADI_03276	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPCAFADI_03277	9.75e-255	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IPCAFADI_03278	8.83e-242	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_03279	1.07e-160	yvbU	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03280	2.96e-193	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IPCAFADI_03281	2.33e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_03283	1.01e-190	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
IPCAFADI_03284	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IPCAFADI_03285	1.08e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IPCAFADI_03286	9.33e-169	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPCAFADI_03287	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IPCAFADI_03288	9.77e-170	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPCAFADI_03289	1.63e-261	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_03290	1.16e-151	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IPCAFADI_03291	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IPCAFADI_03292	3.8e-292	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IPCAFADI_03293	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
IPCAFADI_03294	1.56e-228	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IPCAFADI_03295	3.97e-275	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IPCAFADI_03296	1.04e-69	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IPCAFADI_03297	5.68e-133	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPCAFADI_03298	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_03299	1.99e-238	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_03300	2.29e-251	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IPCAFADI_03301	1.48e-245	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IPCAFADI_03302	3.85e-259	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IPCAFADI_03303	9.28e-252	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IPCAFADI_03304	4.18e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCAFADI_03305	4.42e-271	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IPCAFADI_03306	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IPCAFADI_03307	2.57e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IPCAFADI_03308	5.33e-152	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IPCAFADI_03309	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IPCAFADI_03310	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IPCAFADI_03311	9.69e-110	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IPCAFADI_03312	5.45e-167	-	-	-	CH	-	-	-	FAD binding domain
IPCAFADI_03313	6.76e-99	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IPCAFADI_03314	1.05e-136	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IPCAFADI_03315	1.27e-108	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCAFADI_03316	7.09e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IPCAFADI_03317	1.05e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IPCAFADI_03318	1.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPCAFADI_03320	7.39e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPCAFADI_03321	1.71e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPCAFADI_03322	1.2e-291	-	-	-	I	-	-	-	Pfam Lipase (class 3)
IPCAFADI_03323	2.17e-44	-	-	-	-	-	-	-	-
IPCAFADI_03325	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IPCAFADI_03326	5.13e-267	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
IPCAFADI_03327	2.57e-224	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
IPCAFADI_03328	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPCAFADI_03329	8.63e-44	yraN	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03330	1.47e-15	-	-	-	-	-	-	-	-
IPCAFADI_03331	2.87e-132	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IPCAFADI_03332	8.49e-66	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IPCAFADI_03333	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IPCAFADI_03334	8.55e-135	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IPCAFADI_03335	2.21e-228	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCAFADI_03336	2.04e-100	-	-	-	M	-	-	-	Ribonuclease
IPCAFADI_03337	1.66e-166	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IPCAFADI_03338	6.52e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IPCAFADI_03339	2.98e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IPCAFADI_03340	3.51e-223	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IPCAFADI_03341	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IPCAFADI_03342	8.55e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPCAFADI_03343	4.78e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPCAFADI_03344	1.28e-187	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IPCAFADI_03345	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPCAFADI_03346	2.88e-231	sasA	-	-	T	-	-	-	Histidine kinase
IPCAFADI_03347	1.49e-153	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_03348	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IPCAFADI_03349	2.5e-138	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IPCAFADI_03350	5.4e-174	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IPCAFADI_03351	5.16e-164	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPCAFADI_03352	1.29e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPCAFADI_03353	1.36e-136	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IPCAFADI_03354	9.29e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPCAFADI_03355	1.45e-145	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IPCAFADI_03356	3.98e-259	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IPCAFADI_03357	5.06e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IPCAFADI_03358	3.06e-113	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IPCAFADI_03359	6.41e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IPCAFADI_03360	1.69e-191	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPCAFADI_03361	1.72e-215	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPCAFADI_03362	7.39e-274	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPCAFADI_03363	1.44e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPCAFADI_03364	1.01e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IPCAFADI_03365	3.63e-211	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IPCAFADI_03366	1.21e-124	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IPCAFADI_03367	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IPCAFADI_03368	1.09e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IPCAFADI_03369	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IPCAFADI_03370	4.14e-214	yvlB	-	-	S	-	-	-	Putative adhesin
IPCAFADI_03371	1.79e-61	yvlA	-	-	-	-	-	-	-
IPCAFADI_03372	1.29e-40	yvkN	-	-	-	-	-	-	-
IPCAFADI_03373	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPCAFADI_03374	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPCAFADI_03375	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03376	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IPCAFADI_03377	6.77e-121	yvkB	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03378	4.95e-290	yvkA	-	-	P	-	-	-	-transporter
IPCAFADI_03380	9.81e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCAFADI_03381	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IPCAFADI_03382	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IPCAFADI_03383	4.73e-272	ywoF	-	-	P	-	-	-	Right handed beta helix region
IPCAFADI_03384	1.43e-197	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IPCAFADI_03385	3.53e-158	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IPCAFADI_03386	9.9e-57	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IPCAFADI_03387	5.39e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_03388	1.08e-222	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPCAFADI_03389	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPCAFADI_03390	4.61e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPCAFADI_03391	1.3e-87	-	-	-	-	-	-	-	-
IPCAFADI_03392	1.1e-10	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IPCAFADI_03393	6.25e-83	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IPCAFADI_03394	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IPCAFADI_03395	9.98e-154	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPCAFADI_03396	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IPCAFADI_03397	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IPCAFADI_03398	3.12e-105	yviE	-	-	-	-	-	-	-
IPCAFADI_03399	4.01e-207	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IPCAFADI_03400	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IPCAFADI_03401	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
IPCAFADI_03402	2.06e-51	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IPCAFADI_03403	2.06e-93	yvyF	-	-	S	-	-	-	flagellar protein
IPCAFADI_03404	1.04e-80	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IPCAFADI_03405	2.93e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IPCAFADI_03406	5.41e-316	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IPCAFADI_03407	1.91e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03408	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCAFADI_03409	6.62e-245	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IPCAFADI_03410	3.85e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IPCAFADI_03411	3.87e-234	yvhJ	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03412	1.8e-232	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IPCAFADI_03413	2.25e-285	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IPCAFADI_03414	7.45e-181	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IPCAFADI_03415	1.63e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IPCAFADI_03416	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IPCAFADI_03417	6.12e-312	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPCAFADI_03418	7.91e-270	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IPCAFADI_03419	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCAFADI_03420	8.51e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPCAFADI_03421	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPCAFADI_03422	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
IPCAFADI_03423	4.4e-63	-	-	-	-	-	-	-	-
IPCAFADI_03424	5e-201	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IPCAFADI_03425	3.99e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPCAFADI_03426	3.45e-207	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IPCAFADI_03427	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IPCAFADI_03428	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IPCAFADI_03429	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPCAFADI_03430	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IPCAFADI_03431	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IPCAFADI_03432	1.18e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IPCAFADI_03433	6.88e-259	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPCAFADI_03434	1.7e-300	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPCAFADI_03435	1.15e-232	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPCAFADI_03436	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPCAFADI_03437	4.37e-245	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IPCAFADI_03438	5.1e-264	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IPCAFADI_03439	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
IPCAFADI_03440	1.37e-305	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPCAFADI_03441	7.06e-224	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03442	2.31e-196	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IPCAFADI_03444	3.63e-18	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IPCAFADI_03445	7.63e-41	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCAFADI_03446	6.63e-31	-	-	-	-	-	-	-	-
IPCAFADI_03447	2.76e-288	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPCAFADI_03448	1.93e-27	ywtC	-	-	-	-	-	-	-
IPCAFADI_03449	7.41e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IPCAFADI_03450	4.18e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IPCAFADI_03451	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IPCAFADI_03452	2.45e-253	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
IPCAFADI_03453	2.32e-226	-	-	-	E	-	-	-	Spore germination protein
IPCAFADI_03454	1.59e-247	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
IPCAFADI_03455	2.53e-220	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
IPCAFADI_03456	1.17e-193	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPCAFADI_03457	4.43e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPCAFADI_03458	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IPCAFADI_03459	7.29e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPCAFADI_03460	3.84e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IPCAFADI_03461	1.55e-111	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IPCAFADI_03462	1.22e-114	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IPCAFADI_03463	1.06e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IPCAFADI_03464	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IPCAFADI_03465	6.98e-211	alsR	-	-	K	-	-	-	LysR substrate binding domain
IPCAFADI_03466	2.51e-298	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPCAFADI_03467	9.74e-154	ywrJ	-	-	-	-	-	-	-
IPCAFADI_03468	7.28e-167	cotB	-	-	-	ko:K06325	-	ko00000	-
IPCAFADI_03469	1.51e-259	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IPCAFADI_03470	9.14e-14	-	-	-	-	-	-	-	-
IPCAFADI_03471	6.15e-139	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IPCAFADI_03472	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IPCAFADI_03473	3.81e-105	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IPCAFADI_03474	7.48e-126	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IPCAFADI_03475	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IPCAFADI_03476	9.93e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IPCAFADI_03477	1.66e-21	-	-	-	-	-	-	-	-
IPCAFADI_03478	8.64e-118	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IPCAFADI_03479	2.04e-90	-	-	-	S	-	-	-	Immunity protein Imm6
IPCAFADI_03480	3.9e-85	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
IPCAFADI_03481	1.02e-82	-	-	-	-	-	-	-	-
IPCAFADI_03482	6.52e-98	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
IPCAFADI_03483	4.55e-84	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
IPCAFADI_03484	9.23e-297	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IPCAFADI_03485	1.59e-47	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IPCAFADI_03487	3.69e-186	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IPCAFADI_03488	2.45e-304	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPCAFADI_03489	8e-177	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IPCAFADI_03490	1.79e-147	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IPCAFADI_03491	1.2e-143	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IPCAFADI_03492	3e-22	-	-	-	-	-	-	-	-
IPCAFADI_03493	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IPCAFADI_03494	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPCAFADI_03495	6.34e-194	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IPCAFADI_03496	2.67e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IPCAFADI_03497	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IPCAFADI_03498	1.06e-73	ywpG	-	-	-	-	-	-	-
IPCAFADI_03499	1.79e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
IPCAFADI_03500	2.54e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPCAFADI_03501	3.68e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPCAFADI_03502	7.62e-248	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IPCAFADI_03503	1.12e-179	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IPCAFADI_03504	8.13e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IPCAFADI_03505	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IPCAFADI_03506	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IPCAFADI_03507	3.07e-92	ywoH	-	-	K	-	-	-	transcriptional
IPCAFADI_03508	1.12e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPCAFADI_03509	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IPCAFADI_03510	6.05e-307	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IPCAFADI_03511	5.17e-129	yjgF	-	-	Q	-	-	-	Isochorismatase family
IPCAFADI_03512	1.27e-289	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IPCAFADI_03513	1.51e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IPCAFADI_03514	1.58e-262	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IPCAFADI_03515	5.56e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IPCAFADI_03516	6.12e-91	ywnJ	-	-	S	-	-	-	VanZ like family
IPCAFADI_03517	1.17e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IPCAFADI_03518	6.25e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IPCAFADI_03520	7.02e-88	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IPCAFADI_03521	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPCAFADI_03522	5.66e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IPCAFADI_03523	4.36e-115	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IPCAFADI_03524	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03525	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IPCAFADI_03526	1.25e-80	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IPCAFADI_03527	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IPCAFADI_03528	2.41e-16	csbD	-	-	K	-	-	-	CsbD-like
IPCAFADI_03529	1.99e-107	ywmF	-	-	S	-	-	-	Peptidase M50
IPCAFADI_03530	1.44e-114	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPCAFADI_03532	2.97e-243	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPCAFADI_03533	1.01e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IPCAFADI_03535	2.79e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPCAFADI_03536	3.34e-145	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPCAFADI_03537	2.29e-230	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IPCAFADI_03538	1.85e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPCAFADI_03539	6.16e-163	ywmB	-	-	S	-	-	-	TATA-box binding
IPCAFADI_03540	1.85e-44	ywzB	-	-	S	-	-	-	membrane
IPCAFADI_03541	1.98e-115	ywmA	-	-	-	-	-	-	-
IPCAFADI_03542	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IPCAFADI_03543	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPCAFADI_03544	3.14e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPCAFADI_03545	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPCAFADI_03546	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPCAFADI_03547	3.35e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPCAFADI_03548	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPCAFADI_03549	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IPCAFADI_03550	3.7e-79	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IPCAFADI_03551	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPCAFADI_03552	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPCAFADI_03553	2.39e-121	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IPCAFADI_03554	9.2e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IPCAFADI_03555	8.75e-94	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPCAFADI_03556	2.17e-115	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IPCAFADI_03557	1.15e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPCAFADI_03558	6.75e-96	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IPCAFADI_03559	1.42e-147	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IPCAFADI_03560	4.72e-76	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IPCAFADI_03562	8.7e-197	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPCAFADI_03563	6.16e-242	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPCAFADI_03564	2.93e-85	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_03565	2.63e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IPCAFADI_03566	6.87e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IPCAFADI_03567	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IPCAFADI_03568	3.76e-130	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IPCAFADI_03569	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IPCAFADI_03570	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPCAFADI_03571	1.18e-223	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IPCAFADI_03572	1.59e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPCAFADI_03573	2.59e-143	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPCAFADI_03574	4.53e-203	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IPCAFADI_03575	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IPCAFADI_03576	1.57e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IPCAFADI_03577	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPCAFADI_03578	8.04e-69	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPCAFADI_03579	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IPCAFADI_03580	4.33e-263	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IPCAFADI_03581	1.32e-224	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IPCAFADI_03582	6.53e-58	ywjC	-	-	-	-	-	-	-
IPCAFADI_03583	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IPCAFADI_03584	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPCAFADI_03585	1.38e-150	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
IPCAFADI_03586	4.54e-112	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
IPCAFADI_03587	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
IPCAFADI_03588	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCAFADI_03589	3.37e-97	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
IPCAFADI_03590	4.26e-162	ywiC	-	-	S	-	-	-	YwiC-like protein
IPCAFADI_03591	5.83e-162	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
IPCAFADI_03592	3.08e-266	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IPCAFADI_03593	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IPCAFADI_03594	3.14e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03595	1.63e-250	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IPCAFADI_03596	3.94e-92	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPCAFADI_03598	1.73e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IPCAFADI_03599	6.45e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IPCAFADI_03600	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPCAFADI_03601	2.38e-90	-	-	-	-	-	-	-	-
IPCAFADI_03602	1.2e-115	ywhD	-	-	S	-	-	-	YwhD family
IPCAFADI_03603	1.1e-152	ywhC	-	-	S	-	-	-	Peptidase family M50
IPCAFADI_03604	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IPCAFADI_03605	9.43e-90	ywhA	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03606	2.77e-306	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
IPCAFADI_03607	1.17e-114	ywgA	-	-	-	ko:K09388	-	ko00000	-
IPCAFADI_03608	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IPCAFADI_03609	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IPCAFADI_03610	4.35e-139	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IPCAFADI_03611	1.27e-66	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
IPCAFADI_03612	3.57e-109	-	-	-	S	-	-	-	membrane
IPCAFADI_03613	1.58e-193	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_03614	6.11e-208	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IPCAFADI_03617	1.6e-210	-	-	-	-	-	-	-	-
IPCAFADI_03619	5.43e-196	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IPCAFADI_03620	3.96e-201	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IPCAFADI_03621	2.02e-205	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IPCAFADI_03622	1.32e-221	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IPCAFADI_03623	1.9e-184	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IPCAFADI_03624	4.28e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IPCAFADI_03625	7.93e-291	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IPCAFADI_03626	5.73e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IPCAFADI_03627	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IPCAFADI_03628	2.69e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCAFADI_03629	1.63e-174	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IPCAFADI_03630	4.49e-143	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IPCAFADI_03631	3.64e-273	ywfA	-	-	EGP	-	-	-	-transporter
IPCAFADI_03632	3.74e-253	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IPCAFADI_03633	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPCAFADI_03634	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IPCAFADI_03635	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPCAFADI_03636	8.64e-312	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPCAFADI_03637	4.02e-80	-	-	-	-	-	-	-	-
IPCAFADI_03638	6.39e-110	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IPCAFADI_03639	2.42e-201	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IPCAFADI_03640	8.01e-226	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IPCAFADI_03641	7.12e-171	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IPCAFADI_03642	1.05e-212	spsG	-	-	M	-	-	-	Spore Coat
IPCAFADI_03643	3.73e-160	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IPCAFADI_03644	2.97e-266	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IPCAFADI_03645	7.72e-196	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IPCAFADI_03646	1.34e-277	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IPCAFADI_03647	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IPCAFADI_03648	1.18e-179	spsA	-	-	M	-	-	-	Spore Coat
IPCAFADI_03649	1.16e-86	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IPCAFADI_03650	1.26e-75	ywdK	-	-	S	-	-	-	small membrane protein
IPCAFADI_03651	9.93e-287	ywdJ	-	-	F	-	-	-	Xanthine uracil
IPCAFADI_03652	1.45e-58	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IPCAFADI_03653	2.42e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPCAFADI_03654	5.02e-187	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IPCAFADI_03655	1.61e-184	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IPCAFADI_03656	1.75e-26	ywdA	-	-	-	-	-	-	-
IPCAFADI_03657	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IPCAFADI_03658	3.61e-316	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_03659	2.6e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPCAFADI_03661	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPCAFADI_03662	1.83e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCAFADI_03663	1.28e-175	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IPCAFADI_03664	1.84e-262	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IPCAFADI_03665	2.59e-91	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IPCAFADI_03666	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IPCAFADI_03667	2.55e-79	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IPCAFADI_03668	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IPCAFADI_03669	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPCAFADI_03670	3.01e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IPCAFADI_03671	5.74e-48	ydaS	-	-	S	-	-	-	membrane
IPCAFADI_03672	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IPCAFADI_03673	1.07e-265	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPCAFADI_03674	1.11e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
IPCAFADI_03675	1.21e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IPCAFADI_03677	6.64e-162	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
IPCAFADI_03678	2.14e-157	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
IPCAFADI_03679	7.85e-139	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPCAFADI_03680	1.14e-295	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IPCAFADI_03681	2.89e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IPCAFADI_03682	1.47e-247	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IPCAFADI_03683	5.73e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPCAFADI_03684	8.96e-167	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPCAFADI_03685	1.33e-199	ywbI	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03686	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IPCAFADI_03687	1.78e-141	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IPCAFADI_03688	1.52e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IPCAFADI_03689	4.21e-165	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IPCAFADI_03690	2.79e-200	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IPCAFADI_03693	1.57e-73	-	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03694	2.71e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IPCAFADI_03695	1.24e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IPCAFADI_03696	3.53e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCAFADI_03697	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPCAFADI_03698	3.5e-206	gspA	-	-	M	-	-	-	General stress
IPCAFADI_03699	2.5e-64	ywaE	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03700	4.08e-248	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPCAFADI_03701	2.16e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
IPCAFADI_03702	7.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IPCAFADI_03703	3.51e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IPCAFADI_03704	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_03705	5.16e-291	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IPCAFADI_03706	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCAFADI_03707	8.15e-285	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPCAFADI_03708	7.16e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IPCAFADI_03709	9.4e-317	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPCAFADI_03710	3.97e-66	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPCAFADI_03711	2.51e-314	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCAFADI_03712	3.67e-65	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IPCAFADI_03713	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IPCAFADI_03714	1.42e-139	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IPCAFADI_03715	9.05e-218	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_03716	3.8e-228	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCAFADI_03717	1.53e-212	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IPCAFADI_03718	1.06e-66	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IPCAFADI_03719	3.88e-285	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPCAFADI_03720	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPCAFADI_03721	5.13e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IPCAFADI_03722	2.76e-316	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IPCAFADI_03723	2.23e-194	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPCAFADI_03724	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IPCAFADI_03725	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IPCAFADI_03726	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IPCAFADI_03727	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IPCAFADI_03728	3.05e-285	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IPCAFADI_03729	1.38e-190	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IPCAFADI_03730	8.75e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPCAFADI_03731	2.03e-196	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IPCAFADI_03732	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPCAFADI_03734	1.23e-109	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IPCAFADI_03735	1.42e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IPCAFADI_03736	1.57e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IPCAFADI_03739	6.59e-106	yxjI	-	-	S	-	-	-	LURP-one-related
IPCAFADI_03740	6.78e-270	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IPCAFADI_03741	3.84e-183	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IPCAFADI_03742	4.12e-261	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCAFADI_03743	8.11e-114	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IPCAFADI_03744	8.29e-66	yxiS	-	-	-	-	-	-	-
IPCAFADI_03746	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPCAFADI_03747	1.83e-280	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IPCAFADI_03748	1.18e-176	bglS	-	-	M	-	-	-	licheninase activity
IPCAFADI_03749	8.3e-72	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPCAFADI_03750	4.76e-78	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPCAFADI_03751	4.56e-276	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IPCAFADI_03752	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IPCAFADI_03755	1.6e-77	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IPCAFADI_03756	4.2e-103	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
IPCAFADI_03758	5.93e-28	-	-	-	-	-	-	-	-
IPCAFADI_03759	8.85e-11	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IPCAFADI_03760	1.39e-140	-	-	-	-	-	-	-	-
IPCAFADI_03761	2e-101	-	-	-	-	-	-	-	-
IPCAFADI_03765	7.15e-86	yxiG	-	-	-	-	-	-	-
IPCAFADI_03768	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IPCAFADI_03769	2.59e-255	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IPCAFADI_03770	7.42e-202	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IPCAFADI_03771	8.16e-93	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IPCAFADI_03772	0.0	-	-	-	L	-	-	-	HKD family nuclease
IPCAFADI_03773	1.38e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPCAFADI_03774	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IPCAFADI_03775	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IPCAFADI_03776	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
IPCAFADI_03777	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IPCAFADI_03778	6.29e-290	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
IPCAFADI_03779	3.89e-215	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IPCAFADI_03780	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPCAFADI_03781	6.37e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IPCAFADI_03782	1.16e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCAFADI_03783	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IPCAFADI_03784	6.49e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPCAFADI_03785	6.11e-189	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IPCAFADI_03788	3.04e-22	yxeE	-	-	-	-	-	-	-
IPCAFADI_03790	9.67e-33	yxeD	-	-	-	-	-	-	-
IPCAFADI_03791	3.43e-47	-	-	-	-	-	-	-	-
IPCAFADI_03792	1.66e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IPCAFADI_03793	2.25e-72	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IPCAFADI_03794	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IPCAFADI_03795	1.28e-179	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPCAFADI_03796	2.28e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03797	4.45e-157	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_03798	2.67e-193	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IPCAFADI_03799	1.15e-198	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IPCAFADI_03800	8.51e-210	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IPCAFADI_03801	4.76e-246	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IPCAFADI_03802	2.76e-289	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IPCAFADI_03803	3.65e-220	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IPCAFADI_03804	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IPCAFADI_03805	2.47e-225	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IPCAFADI_03806	1.35e-197	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IPCAFADI_03807	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCAFADI_03808	7.11e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPCAFADI_03809	3.78e-219	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IPCAFADI_03810	6.11e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPCAFADI_03811	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IPCAFADI_03812	1.89e-189	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IPCAFADI_03813	2.06e-129	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCAFADI_03814	9.47e-245	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03815	2.56e-248	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IPCAFADI_03816	2.95e-263	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IPCAFADI_03817	5.9e-314	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPCAFADI_03818	2.12e-185	yxaL	-	-	S	-	-	-	PQQ-like domain
IPCAFADI_03819	1.43e-75	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IPCAFADI_03820	2.01e-66	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPCAFADI_03821	2.01e-251	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IPCAFADI_03822	1.56e-87	yxaI	-	-	S	-	-	-	membrane protein domain
IPCAFADI_03823	9.32e-154	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
IPCAFADI_03824	1.55e-134	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IPCAFADI_03825	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IPCAFADI_03826	1.47e-233	mrjp	-	-	G	-	-	-	Major royal jelly protein
IPCAFADI_03827	4.38e-302	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IPCAFADI_03828	5.54e-201	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
IPCAFADI_03829	1.26e-96	-	-	-	K	-	-	-	Integron-associated effector binding protein
IPCAFADI_03830	5.4e-99	yjhE	-	-	S	-	-	-	Phage tail protein
IPCAFADI_03831	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IPCAFADI_03832	1.2e-101	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IPCAFADI_03833	3.89e-181	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IPCAFADI_03834	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IPCAFADI_03835	1.82e-110	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IPCAFADI_03836	5.41e-213	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IPCAFADI_03837	1.39e-210	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IPCAFADI_03840	0.0	-	-	-	LO	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IPCAFADI_03841	5.84e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPCAFADI_03843	2.32e-261	yycP	-	-	-	-	-	-	-
IPCAFADI_03844	4.41e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IPCAFADI_03845	1.05e-224	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IPCAFADI_03846	1.5e-106	yycN	-	-	K	-	-	-	Acetyltransferase
IPCAFADI_03848	2.29e-253	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
IPCAFADI_03849	8.48e-209	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IPCAFADI_03850	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPCAFADI_03851	8.65e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IPCAFADI_03852	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IPCAFADI_03853	5.8e-255	-	-	-	S	-	-	-	Major Facilitator Superfamily
IPCAFADI_03854	9.11e-302	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IPCAFADI_03855	1.25e-90	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
IPCAFADI_03856	1.74e-273	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCAFADI_03857	3.29e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IPCAFADI_03858	1.82e-190	yycI	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03859	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03860	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPCAFADI_03861	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCAFADI_03866	4.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPCAFADI_03867	6.15e-92	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_03868	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IPCAFADI_03869	3.13e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IPCAFADI_03871	4.22e-24	yycC	-	-	K	-	-	-	YycC-like protein
IPCAFADI_03872	1.32e-276	-	-	-	M	-	-	-	Glycosyltransferase Family 4
IPCAFADI_03873	2.02e-246	-	-	-	S	-	-	-	Ecdysteroid kinase
IPCAFADI_03874	7.36e-294	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
IPCAFADI_03875	6.12e-283	-	-	-	M	-	-	-	Glycosyltransferase Family 4
IPCAFADI_03876	1.15e-152	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
IPCAFADI_03877	1.25e-109	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
IPCAFADI_03878	6.45e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IPCAFADI_03879	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IPCAFADI_03880	7.75e-192	yybS	-	-	S	-	-	-	membrane
IPCAFADI_03882	1.13e-103	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IPCAFADI_03883	1.79e-84	yybR	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03884	3.44e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IPCAFADI_03885	1.54e-192	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPCAFADI_03886	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IPCAFADI_03887	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IPCAFADI_03888	6.52e-143	-	-	-	K	-	-	-	FCD domain
IPCAFADI_03889	2.25e-116	-	-	-	S	-	-	-	PFAM DinB family protein
IPCAFADI_03890	5.34e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IPCAFADI_03891	1.56e-144	ydgI	-	-	C	-	-	-	nitroreductase
IPCAFADI_03892	1.47e-84	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IPCAFADI_03893	5.77e-189	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPCAFADI_03894	1.78e-97	yybA	-	-	K	-	-	-	transcriptional
IPCAFADI_03895	4.21e-94	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IPCAFADI_03896	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCAFADI_03897	6.92e-176	-	-	-	EG	-	-	-	EamA-like transporter family
IPCAFADI_03898	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IPCAFADI_03899	2.11e-196	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IPCAFADI_03900	4.63e-310	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IPCAFADI_03901	9.47e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCAFADI_03902	1.48e-217	ccpB	-	-	K	-	-	-	Transcriptional regulator
IPCAFADI_03903	2.6e-181	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IPCAFADI_03904	4.14e-115	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPCAFADI_03905	2.63e-125	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
IPCAFADI_03906	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPCAFADI_03907	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPCAFADI_03908	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IPCAFADI_03909	3.13e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPCAFADI_03910	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCAFADI_03911	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IPCAFADI_03912	5.7e-217	yyaD	-	-	S	-	-	-	Membrane
IPCAFADI_03913	3.72e-139	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IPCAFADI_03914	6.79e-188	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IPCAFADI_03915	2.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IPCAFADI_03916	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IPCAFADI_03917	6.29e-162	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IPCAFADI_03918	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPCAFADI_03919	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPCAFADI_03920	3.51e-137	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IPCAFADI_03921	1.23e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPCAFADI_03922	1.84e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme