ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LHDOGKEF_00001 4.48e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHDOGKEF_00002 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LHDOGKEF_00003 1.12e-228 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHDOGKEF_00004 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_00005 1.16e-88 - - - - - - - -
LHDOGKEF_00006 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
LHDOGKEF_00007 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LHDOGKEF_00008 1.9e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHDOGKEF_00009 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LHDOGKEF_00010 1.07e-124 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHDOGKEF_00011 5.01e-164 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LHDOGKEF_00012 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHDOGKEF_00013 3.52e-91 - - - S - - - GtrA-like protein
LHDOGKEF_00014 0.0 - - - S - - - Bacterial membrane protein, YfhO
LHDOGKEF_00015 2.58e-226 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LHDOGKEF_00016 1.19e-156 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
LHDOGKEF_00017 1.4e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LHDOGKEF_00018 2.83e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHDOGKEF_00019 2.97e-50 ynzC - - S - - - UPF0291 protein
LHDOGKEF_00020 3.18e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
LHDOGKEF_00021 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_00022 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_00023 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LHDOGKEF_00024 9.32e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LHDOGKEF_00025 1.59e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LHDOGKEF_00026 6.34e-255 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LHDOGKEF_00027 2.05e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LHDOGKEF_00028 1.45e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHDOGKEF_00029 7.13e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LHDOGKEF_00030 2.53e-114 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHDOGKEF_00031 2.23e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHDOGKEF_00032 1.89e-188 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LHDOGKEF_00033 1.35e-255 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LHDOGKEF_00034 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHDOGKEF_00035 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHDOGKEF_00036 2.39e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LHDOGKEF_00037 3.76e-268 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LHDOGKEF_00038 6.47e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LHDOGKEF_00039 3.95e-65 ylxQ - - J - - - ribosomal protein
LHDOGKEF_00040 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHDOGKEF_00041 9.65e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHDOGKEF_00042 8.54e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHDOGKEF_00043 2.49e-228 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LHDOGKEF_00044 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LHDOGKEF_00045 2.1e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHDOGKEF_00046 7.55e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHDOGKEF_00047 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LHDOGKEF_00048 5.85e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHDOGKEF_00049 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHDOGKEF_00050 6.07e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LHDOGKEF_00051 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LHDOGKEF_00052 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHDOGKEF_00053 7.02e-103 - - - K - - - Acetyltransferase (GNAT) domain
LHDOGKEF_00055 6.15e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LHDOGKEF_00056 1.72e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LHDOGKEF_00057 1.73e-219 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHDOGKEF_00058 4.53e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LHDOGKEF_00059 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHDOGKEF_00060 1.19e-113 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
LHDOGKEF_00061 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
LHDOGKEF_00062 3.72e-201 lysR5 - - K - - - LysR substrate binding domain
LHDOGKEF_00063 3.83e-127 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LHDOGKEF_00064 3.35e-291 - - - S - - - Sterol carrier protein domain
LHDOGKEF_00065 8.62e-22 - - - - - - - -
LHDOGKEF_00066 1.82e-139 - - - K - - - LysR substrate binding domain
LHDOGKEF_00067 8.29e-129 - - - - - - - -
LHDOGKEF_00068 3.69e-157 - - - G - - - Antibiotic biosynthesis monooxygenase
LHDOGKEF_00069 0.0 - - - - - - - -
LHDOGKEF_00070 5.4e-282 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHDOGKEF_00071 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
LHDOGKEF_00072 2.86e-05 - - - M - - - Leucine-rich repeat (LRR) protein
LHDOGKEF_00073 0.0 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
LHDOGKEF_00074 1.92e-141 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LHDOGKEF_00075 3.65e-28 - - - S - - - Bacterial protein of unknown function (DUF898)
LHDOGKEF_00076 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LHDOGKEF_00077 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHDOGKEF_00078 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LHDOGKEF_00079 1.58e-282 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LHDOGKEF_00080 4.04e-207 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LHDOGKEF_00081 1.4e-157 - - - - - - - -
LHDOGKEF_00082 2.17e-209 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHDOGKEF_00083 6.31e-144 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHDOGKEF_00084 3.22e-133 - - - S - - - Peptidase family M23
LHDOGKEF_00085 4.68e-197 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LHDOGKEF_00086 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LHDOGKEF_00087 4.38e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LHDOGKEF_00088 1.82e-226 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LHDOGKEF_00089 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHDOGKEF_00090 6.28e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHDOGKEF_00091 5.41e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LHDOGKEF_00092 1.05e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LHDOGKEF_00093 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LHDOGKEF_00094 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHDOGKEF_00095 3.01e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHDOGKEF_00096 2.24e-162 - - - S - - - Peptidase family M23
LHDOGKEF_00097 1.87e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LHDOGKEF_00098 4.48e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LHDOGKEF_00099 3.45e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHDOGKEF_00100 7.64e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LHDOGKEF_00101 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
LHDOGKEF_00102 1.09e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LHDOGKEF_00103 1.51e-174 - - - - - - - -
LHDOGKEF_00104 2.03e-186 - - - - - - - -
LHDOGKEF_00105 3.64e-175 - - - - - - - -
LHDOGKEF_00106 1.04e-37 - - - - - - - -
LHDOGKEF_00107 1.72e-123 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHDOGKEF_00108 1.57e-181 - - - - - - - -
LHDOGKEF_00109 1.05e-228 - - - - - - - -
LHDOGKEF_00110 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LHDOGKEF_00111 1.14e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LHDOGKEF_00112 2.04e-73 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LHDOGKEF_00113 1.18e-140 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LHDOGKEF_00114 1.01e-187 - - - K - - - SIS domain
LHDOGKEF_00115 2.09e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LHDOGKEF_00116 1.64e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LHDOGKEF_00117 3.39e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LHDOGKEF_00118 6.78e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
LHDOGKEF_00119 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LHDOGKEF_00120 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LHDOGKEF_00121 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LHDOGKEF_00122 8.23e-117 ypmB - - S - - - Protein conserved in bacteria
LHDOGKEF_00123 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LHDOGKEF_00124 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LHDOGKEF_00125 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHDOGKEF_00126 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LHDOGKEF_00127 1.99e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LHDOGKEF_00128 1.61e-136 ypsA - - S - - - Belongs to the UPF0398 family
LHDOGKEF_00129 2.83e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LHDOGKEF_00130 2.39e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LHDOGKEF_00131 2.01e-310 cpdA - - S - - - Calcineurin-like phosphoesterase
LHDOGKEF_00132 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LHDOGKEF_00133 6.03e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHDOGKEF_00134 2.88e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHDOGKEF_00135 2.05e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHDOGKEF_00136 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LHDOGKEF_00137 0.0 FbpA - - K - - - Fibronectin-binding protein
LHDOGKEF_00138 2.95e-87 - - - - - - - -
LHDOGKEF_00139 6.18e-205 - - - S - - - EDD domain protein, DegV family
LHDOGKEF_00140 5.95e-250 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
LHDOGKEF_00141 1.03e-100 - - - - - - - -
LHDOGKEF_00142 1.27e-119 flaR - - F - - - topology modulation protein
LHDOGKEF_00143 2.62e-138 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
LHDOGKEF_00144 2.71e-256 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHDOGKEF_00145 3.43e-07 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHDOGKEF_00146 3.92e-76 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHDOGKEF_00147 1.06e-110 rmaD - - K - - - transcriptional
LHDOGKEF_00148 1.74e-272 - - - EGP - - - Transmembrane secretion effector
LHDOGKEF_00149 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_00150 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_00152 3.46e-87 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LHDOGKEF_00153 4.78e-165 - - - S - - - Protein of unknown function (DUF1275)
LHDOGKEF_00154 9.73e-55 - - - K - - - Helix-turn-helix domain
LHDOGKEF_00155 7.02e-146 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHDOGKEF_00156 3.65e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LHDOGKEF_00157 3.72e-237 - - - K - - - Transcriptional regulator
LHDOGKEF_00158 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHDOGKEF_00159 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHDOGKEF_00160 1.9e-140 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHDOGKEF_00161 1.17e-130 - - - - - - - -
LHDOGKEF_00162 8.53e-215 - - - S - - - Conserved hypothetical protein 698
LHDOGKEF_00163 1.43e-24 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
LHDOGKEF_00164 4.13e-18 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHDOGKEF_00165 6e-59 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHDOGKEF_00166 1.37e-15 - - - S - - - Alpha beta hydrolase
LHDOGKEF_00167 0.0 yagE - - E - - - amino acid
LHDOGKEF_00169 2.54e-101 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LHDOGKEF_00170 1.39e-190 - - - P - - - FAD-binding domain
LHDOGKEF_00171 3.1e-30 - - - C - - - Flavodoxin
LHDOGKEF_00172 7.38e-127 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LHDOGKEF_00173 1.29e-182 - - - C - - - Flavodoxin
LHDOGKEF_00174 3.77e-32 - - - - - - - -
LHDOGKEF_00175 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LHDOGKEF_00176 2.88e-130 - - - P - - - esterase
LHDOGKEF_00177 9.87e-139 - - - C - - - Flavodoxin
LHDOGKEF_00179 1.51e-24 - - - C - - - Flavodoxin
LHDOGKEF_00180 1.54e-187 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
LHDOGKEF_00181 7.12e-80 - - - C - - - aldo keto reductase
LHDOGKEF_00182 1.16e-148 - - - C - - - Aldo/keto reductase family
LHDOGKEF_00183 3.78e-72 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LHDOGKEF_00184 1.57e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
LHDOGKEF_00185 4.35e-108 - - - S - - - Pyridoxamine 5'-phosphate oxidase
LHDOGKEF_00186 2.29e-224 yobV3 - - K - - - WYL domain
LHDOGKEF_00187 0.0 - - - - - - - -
LHDOGKEF_00188 0.0 - - - - - - - -
LHDOGKEF_00189 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate carboxylase activity
LHDOGKEF_00190 3.16e-190 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHDOGKEF_00191 6.01e-54 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHDOGKEF_00192 4.4e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHDOGKEF_00193 5.39e-308 steT - - E ko:K03294 - ko00000 amino acid
LHDOGKEF_00194 2.81e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LHDOGKEF_00195 2.51e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LHDOGKEF_00196 2.55e-118 - - - L - - - nuclease
LHDOGKEF_00197 3.03e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHDOGKEF_00198 1.23e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LHDOGKEF_00199 5.33e-147 - - - S - - - L,D-transpeptidase catalytic domain
LHDOGKEF_00200 2.27e-248 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LHDOGKEF_00201 2.2e-310 - - - L ko:K07478 - ko00000 AAA C-terminal domain
LHDOGKEF_00202 3.74e-130 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
LHDOGKEF_00203 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LHDOGKEF_00204 3.77e-216 mleR - - K - - - LysR family
LHDOGKEF_00205 8.78e-52 - - - - - - - -
LHDOGKEF_00206 9.6e-137 - - - - - - - -
LHDOGKEF_00207 2.58e-67 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LHDOGKEF_00208 1.24e-47 - - - - - - - -
LHDOGKEF_00209 1.79e-144 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
LHDOGKEF_00210 1.06e-185 - - - F - - - Phosphorylase superfamily
LHDOGKEF_00211 2.07e-189 - - - F - - - Phosphorylase superfamily
LHDOGKEF_00212 3.34e-139 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
LHDOGKEF_00213 2.72e-188 - - - F - - - Phosphorylase superfamily
LHDOGKEF_00214 1.22e-103 - - - - - - - -
LHDOGKEF_00215 6.2e-131 - - - - - - - -
LHDOGKEF_00216 1.62e-135 - - - S - - - Alpha/beta hydrolase family
LHDOGKEF_00217 4.91e-121 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHDOGKEF_00218 5.21e-82 - - - - - - - -
LHDOGKEF_00219 1.24e-113 - - - FG - - - HIT domain
LHDOGKEF_00220 2.43e-100 - - - - - - - -
LHDOGKEF_00221 2.53e-152 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LHDOGKEF_00222 1.7e-199 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
LHDOGKEF_00223 9.73e-275 - - - EGP - - - Major Facilitator Superfamily
LHDOGKEF_00224 3.18e-167 - - - F - - - glutamine amidotransferase
LHDOGKEF_00225 3.18e-140 - - - - - - - -
LHDOGKEF_00226 1.41e-141 - - - - - - - -
LHDOGKEF_00227 5.1e-43 - - - - - - - -
LHDOGKEF_00228 1.81e-223 - - - S ko:K07045 - ko00000 Amidohydrolase
LHDOGKEF_00229 1.72e-142 - - - G - - - Phosphoglycerate mutase family
LHDOGKEF_00230 2.66e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LHDOGKEF_00231 3.59e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_00232 6.13e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00233 2.48e-131 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00234 3.25e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
LHDOGKEF_00235 4.2e-42 lysR - - K - - - Transcriptional regulator
LHDOGKEF_00236 2.77e-220 - - - - - - - -
LHDOGKEF_00237 3.34e-211 - - - S - - - reductase
LHDOGKEF_00238 8.07e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHDOGKEF_00239 2.07e-102 - - - K - - - Transcriptional regulator
LHDOGKEF_00240 2.77e-134 - - - - - - - -
LHDOGKEF_00243 1.7e-133 - - - K - - - Acetyltransferase (GNAT) domain
LHDOGKEF_00244 5.42e-275 - - - S - - - SLAP domain
LHDOGKEF_00245 1.31e-211 yvgN - - C - - - Aldo keto reductase
LHDOGKEF_00246 1.08e-212 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LHDOGKEF_00247 6.27e-215 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
LHDOGKEF_00248 5.96e-205 - - - K - - - Transcriptional regulator
LHDOGKEF_00249 5.93e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
LHDOGKEF_00250 1.72e-208 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
LHDOGKEF_00251 9.5e-39 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LHDOGKEF_00252 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHDOGKEF_00253 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHDOGKEF_00254 2.61e-19 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHDOGKEF_00255 7.57e-211 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHDOGKEF_00256 5.84e-129 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHDOGKEF_00257 5.68e-165 - - - M - - - Glycosyl transferases group 1
LHDOGKEF_00258 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LHDOGKEF_00259 2.78e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LHDOGKEF_00260 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_00261 5.05e-313 - - - - - - - -
LHDOGKEF_00262 1.84e-281 - - - S - - - Putative peptidoglycan binding domain
LHDOGKEF_00263 2.46e-121 - - - S - - - ECF-type riboflavin transporter, S component
LHDOGKEF_00264 2.42e-201 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LHDOGKEF_00265 1.71e-265 - - - V - - - Beta-lactamase
LHDOGKEF_00266 5.22e-89 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHDOGKEF_00267 8.43e-148 - - - I - - - Acid phosphatase homologues
LHDOGKEF_00268 4.33e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
LHDOGKEF_00269 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
LHDOGKEF_00270 1.47e-105 - - - C - - - Flavodoxin
LHDOGKEF_00271 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LHDOGKEF_00272 7.3e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LHDOGKEF_00273 6.35e-154 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LHDOGKEF_00274 1.13e-312 ynbB - - P - - - aluminum resistance
LHDOGKEF_00275 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LHDOGKEF_00276 0.0 - - - E - - - Amino acid permease
LHDOGKEF_00277 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LHDOGKEF_00278 9.18e-83 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHDOGKEF_00279 7.42e-89 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHDOGKEF_00280 2.82e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
LHDOGKEF_00281 1.25e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LHDOGKEF_00282 4.82e-296 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_00283 1.72e-85 - - - - - - - -
LHDOGKEF_00284 7.16e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LHDOGKEF_00285 4.61e-308 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LHDOGKEF_00286 3.29e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LHDOGKEF_00287 2.27e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
LHDOGKEF_00288 2.09e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LHDOGKEF_00289 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHDOGKEF_00290 1.07e-201 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LHDOGKEF_00291 8.96e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHDOGKEF_00292 8.81e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LHDOGKEF_00293 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
LHDOGKEF_00294 1.64e-47 yozE - - S - - - Belongs to the UPF0346 family
LHDOGKEF_00295 6.34e-193 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
LHDOGKEF_00296 7.33e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LHDOGKEF_00297 8.15e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LHDOGKEF_00298 1.3e-207 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHDOGKEF_00299 2.22e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LHDOGKEF_00300 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LHDOGKEF_00301 3.15e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LHDOGKEF_00302 4.07e-270 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LHDOGKEF_00303 1.28e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LHDOGKEF_00304 7.33e-71 - - - M - - - Lysin motif
LHDOGKEF_00305 6.79e-152 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHDOGKEF_00306 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHDOGKEF_00307 5.75e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHDOGKEF_00308 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHDOGKEF_00309 6.56e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHDOGKEF_00310 2.19e-218 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LHDOGKEF_00311 1e-216 yitL - - S ko:K00243 - ko00000 S1 domain
LHDOGKEF_00312 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LHDOGKEF_00313 7.76e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LHDOGKEF_00314 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LHDOGKEF_00315 3.9e-33 - - - S - - - Protein of unknown function (DUF2929)
LHDOGKEF_00316 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHDOGKEF_00317 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LHDOGKEF_00318 2.25e-45 - - - S - - - Lipopolysaccharide assembly protein A domain
LHDOGKEF_00319 1.5e-186 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHDOGKEF_00320 6.35e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LHDOGKEF_00321 0.0 oatA - - I - - - Acyltransferase
LHDOGKEF_00322 3.01e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHDOGKEF_00323 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHDOGKEF_00324 4.52e-140 yngC - - S - - - SNARE associated Golgi protein
LHDOGKEF_00325 5.04e-298 yhdG - - E ko:K03294 - ko00000 Amino Acid
LHDOGKEF_00326 2.31e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHDOGKEF_00327 3.29e-193 yxeH - - S - - - hydrolase
LHDOGKEF_00328 2.72e-197 - - - S - - - reductase
LHDOGKEF_00329 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHDOGKEF_00330 9.94e-287 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHDOGKEF_00331 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LHDOGKEF_00332 1.74e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LHDOGKEF_00333 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHDOGKEF_00334 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHDOGKEF_00335 1.17e-65 - - - - - - - -
LHDOGKEF_00336 1.32e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LHDOGKEF_00337 7.54e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHDOGKEF_00338 3.82e-312 - - - S - - - Putative threonine/serine exporter
LHDOGKEF_00339 1.56e-228 citR - - K - - - Putative sugar-binding domain
LHDOGKEF_00340 5.21e-71 - - - - - - - -
LHDOGKEF_00341 2.09e-83 - - - S - - - Domain of unknown function DUF1828
LHDOGKEF_00342 4.42e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
LHDOGKEF_00343 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00344 1.14e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LHDOGKEF_00345 6.03e-19 - - - - - - - -
LHDOGKEF_00346 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
LHDOGKEF_00347 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LHDOGKEF_00348 6.24e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LHDOGKEF_00349 2.76e-60 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LHDOGKEF_00350 7.35e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LHDOGKEF_00351 7.54e-200 - - - I - - - Alpha/beta hydrolase family
LHDOGKEF_00352 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LHDOGKEF_00353 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LHDOGKEF_00354 5.14e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHDOGKEF_00355 0.0 - - - M - - - domain protein
LHDOGKEF_00356 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LHDOGKEF_00357 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LHDOGKEF_00358 4.45e-127 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00359 2.07e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHDOGKEF_00360 1.03e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHDOGKEF_00361 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
LHDOGKEF_00362 1.53e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHDOGKEF_00363 1.21e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LHDOGKEF_00364 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
LHDOGKEF_00365 2.16e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
LHDOGKEF_00366 9.27e-75 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHDOGKEF_00367 0.000281 - - - - - - - -
LHDOGKEF_00368 1.98e-129 - - - - - - - -
LHDOGKEF_00369 1.09e-34 - - - - - - - -
LHDOGKEF_00370 2.59e-229 int3 - - L - - - Belongs to the 'phage' integrase family
LHDOGKEF_00372 1.47e-244 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LHDOGKEF_00373 2.64e-128 - - - I - - - PAP2 superfamily
LHDOGKEF_00374 1.19e-194 - - - S - - - Uncharacterised protein, DegV family COG1307
LHDOGKEF_00375 2.12e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHDOGKEF_00376 4.93e-141 - - - S - - - Domain of unknown function (DUF4767)
LHDOGKEF_00377 1.01e-111 yfhC - - C - - - Nitroreductase family
LHDOGKEF_00378 3.69e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
LHDOGKEF_00379 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_00380 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_00381 1.91e-55 - - - - - - - -
LHDOGKEF_00382 1.45e-172 - - - K ko:K03492 - ko00000,ko03000 UTRA
LHDOGKEF_00383 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_00384 2.84e-94 - - - S - - - Domain of unknown function (DUF3284)
LHDOGKEF_00385 1.68e-179 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_00386 4.68e-104 - - - - - - - -
LHDOGKEF_00387 4.75e-80 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
LHDOGKEF_00388 4.98e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LHDOGKEF_00389 1.62e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
LHDOGKEF_00390 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_00391 6.28e-10 - - - S - - - CsbD-like
LHDOGKEF_00392 3.08e-52 - - - S - - - Transglycosylase associated protein
LHDOGKEF_00393 4.23e-93 alkD - - L - - - DNA alkylation repair enzyme
LHDOGKEF_00397 8.04e-188 - - - - - - - -
LHDOGKEF_00398 4.65e-228 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
LHDOGKEF_00399 0.0 - - - - - - - -
LHDOGKEF_00400 1.01e-104 - - - - - - - -
LHDOGKEF_00401 1.18e-55 - - - C - - - FMN_bind
LHDOGKEF_00402 0.0 - - - I - - - Protein of unknown function (DUF2974)
LHDOGKEF_00403 8.12e-262 pbpX1 - - V - - - Beta-lactamase
LHDOGKEF_00404 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHDOGKEF_00405 2.42e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHDOGKEF_00406 1.23e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LHDOGKEF_00407 1.14e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHDOGKEF_00408 5.48e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LHDOGKEF_00409 1.39e-106 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LHDOGKEF_00410 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHDOGKEF_00411 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHDOGKEF_00412 7.3e-245 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LHDOGKEF_00413 1.17e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LHDOGKEF_00414 8.42e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHDOGKEF_00415 3.02e-294 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHDOGKEF_00416 8.19e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHDOGKEF_00417 1.45e-195 - - - - - - - -
LHDOGKEF_00418 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHDOGKEF_00419 4.08e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHDOGKEF_00420 3.78e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LHDOGKEF_00421 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LHDOGKEF_00422 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LHDOGKEF_00423 2.19e-131 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LHDOGKEF_00424 1.37e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LHDOGKEF_00425 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHDOGKEF_00426 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LHDOGKEF_00427 4.73e-69 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LHDOGKEF_00428 2.75e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHDOGKEF_00429 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LHDOGKEF_00430 2.52e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHDOGKEF_00431 3.13e-46 ykzG - - S - - - Belongs to the UPF0356 family
LHDOGKEF_00432 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHDOGKEF_00433 1.29e-233 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LHDOGKEF_00434 0.0 - - - L - - - Nuclease-related domain
LHDOGKEF_00435 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LHDOGKEF_00436 2.93e-150 - - - S - - - repeat protein
LHDOGKEF_00437 1.58e-161 pgm - - G - - - Phosphoglycerate mutase family
LHDOGKEF_00438 1.62e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LHDOGKEF_00439 1.47e-76 XK27_04120 - - S - - - Putative amino acid metabolism
LHDOGKEF_00440 1.02e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHDOGKEF_00441 4.49e-42 - - - - - - - -
LHDOGKEF_00442 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LHDOGKEF_00443 8.09e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LHDOGKEF_00444 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHDOGKEF_00445 1.18e-141 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LHDOGKEF_00446 4.87e-193 ylmH - - S - - - S4 domain protein
LHDOGKEF_00447 1.36e-39 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
LHDOGKEF_00448 4.09e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LHDOGKEF_00449 5.9e-313 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHDOGKEF_00450 1.02e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LHDOGKEF_00451 1.71e-182 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LHDOGKEF_00452 4.93e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHDOGKEF_00453 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHDOGKEF_00454 8e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHDOGKEF_00455 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHDOGKEF_00456 1.32e-71 ftsL - - D - - - Cell division protein FtsL
LHDOGKEF_00457 5.41e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHDOGKEF_00458 3.95e-93 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LHDOGKEF_00459 4.84e-71 - - - S - - - Protein of unknown function (DUF3397)
LHDOGKEF_00460 1.45e-14 - - - S - - - Protein of unknown function (DUF4044)
LHDOGKEF_00461 6.61e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
LHDOGKEF_00462 1.82e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LHDOGKEF_00463 2.03e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LHDOGKEF_00464 2.34e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
LHDOGKEF_00465 1.83e-163 - - - S - - - Haloacid dehalogenase-like hydrolase
LHDOGKEF_00466 2.55e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LHDOGKEF_00467 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHDOGKEF_00468 1.56e-165 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHDOGKEF_00469 4.62e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LHDOGKEF_00470 1.29e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LHDOGKEF_00471 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LHDOGKEF_00472 1.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHDOGKEF_00473 9.44e-109 - - - S - - - Protein of unknown function (DUF1694)
LHDOGKEF_00474 1.18e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LHDOGKEF_00475 1.41e-49 - - - - - - - -
LHDOGKEF_00476 6.39e-102 uspA - - T - - - universal stress protein
LHDOGKEF_00477 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LHDOGKEF_00478 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
LHDOGKEF_00479 7.58e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LHDOGKEF_00480 2.04e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LHDOGKEF_00481 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
LHDOGKEF_00482 7.03e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LHDOGKEF_00483 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHDOGKEF_00484 1.22e-220 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHDOGKEF_00485 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHDOGKEF_00486 6.82e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHDOGKEF_00487 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHDOGKEF_00488 4.36e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHDOGKEF_00489 4.13e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LHDOGKEF_00490 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHDOGKEF_00491 4.93e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LHDOGKEF_00492 2.52e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHDOGKEF_00493 1.01e-235 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHDOGKEF_00494 4.64e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LHDOGKEF_00495 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LHDOGKEF_00496 1.58e-266 - - - L - - - Belongs to the 'phage' integrase family
LHDOGKEF_00497 3.5e-75 - - - K - - - Transcriptional
LHDOGKEF_00499 2.58e-49 - - - - - - - -
LHDOGKEF_00500 3.84e-90 - - - - - - - -
LHDOGKEF_00501 6.8e-46 - - - - - - - -
LHDOGKEF_00502 1.18e-47 - - - - - - - -
LHDOGKEF_00503 0.0 - - - S ko:K06919 - ko00000 DNA primase
LHDOGKEF_00504 2.17e-85 - - - - - - - -
LHDOGKEF_00507 7.36e-251 ampC - - V - - - Beta-lactamase
LHDOGKEF_00508 5.4e-316 - - - EGP - - - Major Facilitator
LHDOGKEF_00509 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LHDOGKEF_00510 1.93e-139 vanZ - - V - - - VanZ like family
LHDOGKEF_00511 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LHDOGKEF_00512 1.53e-159 XK27_00915 - - C - - - Luciferase-like monooxygenase
LHDOGKEF_00513 4.37e-81 XK27_00915 - - C - - - Luciferase-like monooxygenase
LHDOGKEF_00514 0.0 yclK - - T - - - Histidine kinase
LHDOGKEF_00515 1.97e-170 - - - K - - - Transcriptional regulatory protein, C terminal
LHDOGKEF_00516 1.68e-81 - - - S - - - SdpI/YhfL protein family
LHDOGKEF_00517 1.86e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHDOGKEF_00518 4.53e-41 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LHDOGKEF_00519 3.52e-224 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LHDOGKEF_00520 1.05e-170 - - - M - - - Protein of unknown function (DUF3737)
LHDOGKEF_00522 1.35e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHDOGKEF_00523 4.19e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LHDOGKEF_00524 2.61e-120 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LHDOGKEF_00525 1.33e-25 - - - - - - - -
LHDOGKEF_00526 9e-94 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
LHDOGKEF_00527 1.55e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LHDOGKEF_00528 5.57e-224 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LHDOGKEF_00529 1.38e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LHDOGKEF_00530 1.97e-171 yebC - - K - - - Transcriptional regulatory protein
LHDOGKEF_00531 2.34e-119 - - - S - - - VanZ like family
LHDOGKEF_00532 1.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHDOGKEF_00534 0.0 - - - E - - - Amino acid permease
LHDOGKEF_00535 6.14e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
LHDOGKEF_00536 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_00537 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_00538 4.66e-196 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LHDOGKEF_00539 1.37e-269 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LHDOGKEF_00540 2.73e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHDOGKEF_00541 7.3e-156 - - - - - - - -
LHDOGKEF_00542 1.45e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LHDOGKEF_00543 4.85e-191 - - - S - - - hydrolase
LHDOGKEF_00544 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHDOGKEF_00545 3.38e-221 ybbR - - S - - - YbbR-like protein
LHDOGKEF_00546 1.06e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHDOGKEF_00547 9.5e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_00548 2.65e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00549 1.04e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00550 2.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LHDOGKEF_00551 7.27e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LHDOGKEF_00552 5.26e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHDOGKEF_00553 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LHDOGKEF_00554 3.84e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LHDOGKEF_00555 1.15e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHDOGKEF_00556 1.02e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LHDOGKEF_00557 1.07e-125 - - - - - - - -
LHDOGKEF_00558 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHDOGKEF_00559 9.96e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LHDOGKEF_00560 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHDOGKEF_00561 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LHDOGKEF_00563 0.0 ycaM - - E - - - amino acid
LHDOGKEF_00564 0.0 - - - S - - - SH3-like domain
LHDOGKEF_00565 2.16e-129 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHDOGKEF_00566 1.17e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LHDOGKEF_00567 3.24e-250 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LHDOGKEF_00568 6e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LHDOGKEF_00569 3.8e-118 - - - S - - - Short repeat of unknown function (DUF308)
LHDOGKEF_00570 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LHDOGKEF_00571 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHDOGKEF_00572 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LHDOGKEF_00573 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LHDOGKEF_00574 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHDOGKEF_00575 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LHDOGKEF_00576 5.82e-272 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LHDOGKEF_00577 4.02e-284 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LHDOGKEF_00578 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LHDOGKEF_00579 9.38e-228 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHDOGKEF_00580 1.71e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LHDOGKEF_00581 4.36e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHDOGKEF_00582 6.85e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LHDOGKEF_00583 1.88e-21 - - - - - - - -
LHDOGKEF_00584 6.43e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHDOGKEF_00585 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHDOGKEF_00586 1.75e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHDOGKEF_00587 7.21e-173 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LHDOGKEF_00588 8.33e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LHDOGKEF_00589 2.05e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LHDOGKEF_00590 3.37e-271 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LHDOGKEF_00591 1.29e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LHDOGKEF_00592 6.24e-247 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHDOGKEF_00593 1.73e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHDOGKEF_00594 1.43e-160 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LHDOGKEF_00595 8.02e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LHDOGKEF_00596 2.26e-306 ymfH - - S - - - Peptidase M16
LHDOGKEF_00597 4.09e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
LHDOGKEF_00598 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHDOGKEF_00599 1.28e-89 - - - S - - - Protein of unknown function (DUF1149)
LHDOGKEF_00600 1.75e-134 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHDOGKEF_00601 8.9e-270 XK27_05220 - - S - - - AI-2E family transporter
LHDOGKEF_00602 8.1e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LHDOGKEF_00603 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
LHDOGKEF_00604 1.06e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LHDOGKEF_00605 8.93e-153 - - - S - - - SNARE associated Golgi protein
LHDOGKEF_00606 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LHDOGKEF_00607 1.81e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHDOGKEF_00608 5.49e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHDOGKEF_00609 1.15e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LHDOGKEF_00610 1.46e-145 - - - S - - - CYTH
LHDOGKEF_00611 7.54e-149 yjbH - - Q - - - Thioredoxin
LHDOGKEF_00612 2.56e-209 coiA - - S ko:K06198 - ko00000 Competence protein
LHDOGKEF_00613 2.91e-175 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LHDOGKEF_00614 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LHDOGKEF_00615 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHDOGKEF_00616 9.05e-55 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LHDOGKEF_00617 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LHDOGKEF_00618 3.43e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
LHDOGKEF_00619 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LHDOGKEF_00620 1.24e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
LHDOGKEF_00621 1.02e-93 - - - - - - - -
LHDOGKEF_00622 7.42e-112 - - - - - - - -
LHDOGKEF_00623 4.13e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LHDOGKEF_00624 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHDOGKEF_00625 2.13e-227 ybcH - - D ko:K06889 - ko00000 Alpha beta
LHDOGKEF_00626 2.95e-61 - - - - - - - -
LHDOGKEF_00627 3.82e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LHDOGKEF_00628 3.42e-278 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LHDOGKEF_00629 3.81e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHDOGKEF_00630 6.78e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHDOGKEF_00631 1.14e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LHDOGKEF_00632 7.02e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LHDOGKEF_00633 8.53e-104 ykuP - - C ko:K03839 - ko00000 Flavodoxin
LHDOGKEF_00634 4.67e-116 gtcA1 - - S - - - Teichoic acid glycosylation protein
LHDOGKEF_00635 4.05e-112 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHDOGKEF_00636 9.9e-240 purR13 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
LHDOGKEF_00637 5.73e-202 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
LHDOGKEF_00638 2.68e-225 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
LHDOGKEF_00639 0.0 glpK3 2.7.1.30 - G ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 FGGY family of carbohydrate kinases, C-terminal domain
LHDOGKEF_00640 1.12e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHDOGKEF_00641 8.07e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LHDOGKEF_00644 2.37e-210 - - - - - - - -
LHDOGKEF_00645 5.77e-214 - - - - - - - -
LHDOGKEF_00646 7.72e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00647 7.05e-171 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LHDOGKEF_00648 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LHDOGKEF_00649 4.04e-304 ynbB - - P - - - aluminum resistance
LHDOGKEF_00650 8.27e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHDOGKEF_00651 1.48e-90 yqhL - - P - - - Rhodanese-like protein
LHDOGKEF_00652 4.01e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LHDOGKEF_00653 4.62e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
LHDOGKEF_00654 3.23e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHDOGKEF_00655 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHDOGKEF_00656 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHDOGKEF_00657 0.0 - - - S - - - membrane
LHDOGKEF_00658 2.46e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
LHDOGKEF_00659 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHDOGKEF_00660 1.06e-69 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
LHDOGKEF_00661 3.51e-17 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
LHDOGKEF_00662 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LHDOGKEF_00663 1.6e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
LHDOGKEF_00664 3.63e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHDOGKEF_00665 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHDOGKEF_00666 2.59e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHDOGKEF_00667 1.24e-83 yodB - - K - - - Transcriptional regulator, HxlR family
LHDOGKEF_00668 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHDOGKEF_00669 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LHDOGKEF_00670 1.89e-209 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHDOGKEF_00671 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHDOGKEF_00672 6.08e-164 csrR - - K - - - response regulator
LHDOGKEF_00673 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LHDOGKEF_00674 9.35e-275 ylbM - - S - - - Belongs to the UPF0348 family
LHDOGKEF_00675 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHDOGKEF_00676 4.06e-145 yqeK - - H - - - Hydrolase, HD family
LHDOGKEF_00677 8.11e-159 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHDOGKEF_00678 4.26e-273 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LHDOGKEF_00679 1.66e-120 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LHDOGKEF_00680 4.78e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
LHDOGKEF_00681 8.82e-241 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LHDOGKEF_00682 4.31e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHDOGKEF_00683 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LHDOGKEF_00684 9.48e-95 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LHDOGKEF_00685 1.92e-118 - - - - - - - -
LHDOGKEF_00686 1.39e-92 - - - S - - - Protein of unknown function (DUF3021)
LHDOGKEF_00687 2.67e-96 - - - K - - - LytTr DNA-binding domain
LHDOGKEF_00688 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHDOGKEF_00689 5.35e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LHDOGKEF_00690 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
LHDOGKEF_00691 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHDOGKEF_00692 5.52e-139 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHDOGKEF_00693 6.72e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LHDOGKEF_00694 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHDOGKEF_00695 0.0 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LHDOGKEF_00696 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LHDOGKEF_00697 3.61e-144 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHDOGKEF_00698 3.52e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LHDOGKEF_00699 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHDOGKEF_00700 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHDOGKEF_00701 1.15e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHDOGKEF_00702 1.88e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHDOGKEF_00703 1.24e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LHDOGKEF_00704 1.85e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHDOGKEF_00705 7.36e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHDOGKEF_00706 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LHDOGKEF_00707 1.9e-160 - - - C - - - Flavodoxin
LHDOGKEF_00708 5.58e-192 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LHDOGKEF_00709 2.68e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
LHDOGKEF_00710 2.76e-249 - - - S - - - Bacteriocin helveticin-J
LHDOGKEF_00711 0.0 - - - M - - - Peptidase family M1 domain
LHDOGKEF_00712 2.45e-227 - - - S - - - SLAP domain
LHDOGKEF_00713 2.29e-166 - - - K - - - helix_turn_helix, mercury resistance
LHDOGKEF_00714 4.08e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHDOGKEF_00715 3.14e-226 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LHDOGKEF_00716 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LHDOGKEF_00717 8.03e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHDOGKEF_00718 2.47e-32 - - - - - - - -
LHDOGKEF_00719 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LHDOGKEF_00720 6.78e-100 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
LHDOGKEF_00721 1.77e-85 - - - S - - - Cupredoxin-like domain
LHDOGKEF_00722 1.09e-65 - - - S - - - Cupredoxin-like domain
LHDOGKEF_00723 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LHDOGKEF_00724 2.91e-234 - - - S - - - DUF218 domain
LHDOGKEF_00725 6.11e-168 - - - S - - - Mitochondrial biogenesis AIM24
LHDOGKEF_00726 6.65e-153 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
LHDOGKEF_00727 1.78e-26 - - - - - - - -
LHDOGKEF_00728 5.17e-273 - - - - - - - -
LHDOGKEF_00729 0.0 eriC - - P ko:K03281 - ko00000 chloride
LHDOGKEF_00730 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHDOGKEF_00731 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LHDOGKEF_00732 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LHDOGKEF_00733 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LHDOGKEF_00734 2.31e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHDOGKEF_00735 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LHDOGKEF_00736 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LHDOGKEF_00737 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHDOGKEF_00738 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHDOGKEF_00739 6.15e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LHDOGKEF_00740 3.1e-269 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHDOGKEF_00741 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHDOGKEF_00742 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHDOGKEF_00743 9.55e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LHDOGKEF_00744 8.43e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHDOGKEF_00745 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHDOGKEF_00746 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LHDOGKEF_00747 6.96e-100 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LHDOGKEF_00748 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LHDOGKEF_00749 1e-220 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
LHDOGKEF_00750 1.38e-225 degV1 - - S - - - DegV family
LHDOGKEF_00751 1.09e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LHDOGKEF_00752 1.38e-33 - - - S - - - CsbD-like
LHDOGKEF_00753 1.47e-41 - - - S - - - Transglycosylase associated protein
LHDOGKEF_00754 1.25e-303 - - - I - - - Protein of unknown function (DUF2974)
LHDOGKEF_00756 7.47e-133 cadD - - P - - - Cadmium resistance transporter
LHDOGKEF_00757 2.41e-77 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LHDOGKEF_00758 2.93e-235 - - - - - - - -
LHDOGKEF_00759 1.08e-71 - - - - - - - -
LHDOGKEF_00760 7.23e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LHDOGKEF_00761 4.15e-120 - - - - - - - -
LHDOGKEF_00762 1.16e-234 - - - EP - - - Plasmid replication protein
LHDOGKEF_00763 1.45e-42 - - - - - - - -
LHDOGKEF_00764 8.39e-299 - - - L - - - Belongs to the 'phage' integrase family
LHDOGKEF_00765 4.37e-43 - - - - - - - -
LHDOGKEF_00766 4.41e-92 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
LHDOGKEF_00767 1.63e-27 - - - S - - - Protein of unknown function (DUF3923)
LHDOGKEF_00770 2.01e-205 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
LHDOGKEF_00771 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_00772 1.5e-295 - - - S - - - LPXTG cell wall anchor motif
LHDOGKEF_00773 1.4e-196 - - - S - - - Putative ABC-transporter type IV
LHDOGKEF_00774 2.37e-129 - - - S - - - Cob(I)alamin adenosyltransferase
LHDOGKEF_00775 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
LHDOGKEF_00776 9.95e-75 - - - S - - - Domain of unknown function (DUF4430)
LHDOGKEF_00777 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
LHDOGKEF_00778 2e-223 ydbI - - K - - - AI-2E family transporter
LHDOGKEF_00779 2.37e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHDOGKEF_00780 9.67e-22 - - - - - - - -
LHDOGKEF_00781 2.79e-313 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LHDOGKEF_00782 6.35e-69 - - - - - - - -
LHDOGKEF_00783 8.29e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00784 3.51e-170 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHDOGKEF_00785 3.82e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LHDOGKEF_00786 1.29e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHDOGKEF_00787 0.0 fusA1 - - J - - - elongation factor G
LHDOGKEF_00788 1.99e-195 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LHDOGKEF_00789 9.66e-41 - - - S - - - endonuclease exonuclease phosphatase family protein
LHDOGKEF_00790 1.63e-172 - - - S - - - endonuclease exonuclease phosphatase family protein
LHDOGKEF_00791 8.28e-15 - - - S - - - interspecies interaction between organisms
LHDOGKEF_00792 5.27e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHDOGKEF_00793 3.08e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHDOGKEF_00794 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
LHDOGKEF_00795 0.0 - - - L - - - Helicase C-terminal domain protein
LHDOGKEF_00796 3.12e-273 pbpX1 - - V - - - Beta-lactamase
LHDOGKEF_00797 6.19e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LHDOGKEF_00798 2.2e-68 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
LHDOGKEF_00799 6.25e-304 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LHDOGKEF_00800 2.45e-214 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
LHDOGKEF_00801 1.09e-135 - - - S - - - Membrane
LHDOGKEF_00802 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_00803 0.0 - - - G ko:K02755,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_00804 2.24e-41 - 2.7.1.208, 2.7.1.211 - G ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LHDOGKEF_00805 2.69e-191 - - - K - - - Helix-turn-helix domain, rpiR family
LHDOGKEF_00806 0.0 - - - - - - - -
LHDOGKEF_00807 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LHDOGKEF_00808 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHDOGKEF_00809 5.52e-71 ytpP - - CO - - - Thioredoxin
LHDOGKEF_00810 9.15e-165 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHDOGKEF_00811 3.37e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LHDOGKEF_00812 3.15e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00813 1.38e-102 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LHDOGKEF_00814 3.51e-74 - - - - - - - -
LHDOGKEF_00815 3.26e-199 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LHDOGKEF_00816 3.19e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHDOGKEF_00817 0.0 yhaN - - L - - - AAA domain
LHDOGKEF_00818 8.31e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
LHDOGKEF_00819 6.93e-72 yheA - - S - - - Belongs to the UPF0342 family
LHDOGKEF_00820 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHDOGKEF_00821 3.09e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHDOGKEF_00822 1.34e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LHDOGKEF_00823 2.79e-154 - - - - - - - -
LHDOGKEF_00824 2.45e-246 - - - C - - - FMN-dependent dehydrogenase
LHDOGKEF_00825 1.48e-217 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LHDOGKEF_00826 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LHDOGKEF_00827 1.06e-164 - - - M - - - ErfK YbiS YcfS YnhG
LHDOGKEF_00828 3.16e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHDOGKEF_00829 3.95e-310 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHDOGKEF_00831 1.19e-71 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LHDOGKEF_00832 4.1e-251 flp - - V - - - Beta-lactamase
LHDOGKEF_00833 3.16e-72 - - - - - - - -
LHDOGKEF_00834 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
LHDOGKEF_00835 4.95e-53 - - - S - - - Enterocin A Immunity
LHDOGKEF_00836 0.0 - - - S - - - domain, Protein
LHDOGKEF_00837 6.41e-105 - - - S - - - Cupin domain
LHDOGKEF_00838 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
LHDOGKEF_00839 1.39e-22 - - - K - - - transcriptional regulator
LHDOGKEF_00840 3.3e-94 - - - K - - - transcriptional regulator
LHDOGKEF_00842 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LHDOGKEF_00843 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LHDOGKEF_00844 7.75e-153 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LHDOGKEF_00845 7.6e-118 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHDOGKEF_00846 1.29e-150 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHDOGKEF_00847 1.37e-36 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LHDOGKEF_00848 0.0 mdr - - EGP - - - Major Facilitator
LHDOGKEF_00849 5.35e-289 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHDOGKEF_00853 2.2e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LHDOGKEF_00854 4.56e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHDOGKEF_00855 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
LHDOGKEF_00856 1.69e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHDOGKEF_00857 1.85e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
LHDOGKEF_00858 5.91e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHDOGKEF_00859 2.65e-80 yabA - - L - - - Involved in initiation control of chromosome replication
LHDOGKEF_00860 9.46e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHDOGKEF_00861 1.29e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LHDOGKEF_00862 6.76e-114 - - - S - - - ECF transporter, substrate-specific component
LHDOGKEF_00863 8.02e-172 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LHDOGKEF_00864 1.49e-138 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LHDOGKEF_00865 5.62e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LHDOGKEF_00866 9.05e-170 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LHDOGKEF_00867 7.2e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LHDOGKEF_00868 4.46e-165 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LHDOGKEF_00869 1.38e-298 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LHDOGKEF_00870 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LHDOGKEF_00871 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LHDOGKEF_00872 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LHDOGKEF_00873 1.24e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LHDOGKEF_00874 6.41e-236 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LHDOGKEF_00875 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LHDOGKEF_00876 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_00877 4.92e-107 - - - - - - - -
LHDOGKEF_00878 1.33e-100 - - - K - - - LytTr DNA-binding domain
LHDOGKEF_00879 2.29e-175 - - - S - - - membrane
LHDOGKEF_00880 2.22e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHDOGKEF_00881 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHDOGKEF_00882 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LHDOGKEF_00883 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHDOGKEF_00884 2.35e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHDOGKEF_00885 1.61e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHDOGKEF_00886 2.41e-83 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LHDOGKEF_00887 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LHDOGKEF_00888 1.32e-255 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHDOGKEF_00889 9.43e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LHDOGKEF_00890 8.26e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LHDOGKEF_00891 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHDOGKEF_00892 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
LHDOGKEF_00893 3.27e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHDOGKEF_00894 2.03e-67 yrzB - - S - - - Belongs to the UPF0473 family
LHDOGKEF_00895 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LHDOGKEF_00896 1.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LHDOGKEF_00897 1.46e-70 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHDOGKEF_00898 2.57e-91 yslB - - S - - - Protein of unknown function (DUF2507)
LHDOGKEF_00899 1.33e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHDOGKEF_00900 1.42e-143 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHDOGKEF_00901 3.18e-165 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LHDOGKEF_00902 2.09e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LHDOGKEF_00903 1.37e-74 - - - - - - - -
LHDOGKEF_00904 4.1e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LHDOGKEF_00905 4.5e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LHDOGKEF_00906 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHDOGKEF_00907 2.5e-74 - - - - - - - -
LHDOGKEF_00908 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHDOGKEF_00909 6.99e-134 yutD - - S - - - Protein of unknown function (DUF1027)
LHDOGKEF_00910 1.9e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LHDOGKEF_00911 3.19e-139 - - - S - - - Protein of unknown function (DUF1461)
LHDOGKEF_00912 1.45e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LHDOGKEF_00913 4.65e-193 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LHDOGKEF_00917 1.19e-107 - - - S - - - COG NOG38524 non supervised orthologous group
LHDOGKEF_00918 1.07e-150 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHDOGKEF_00919 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
LHDOGKEF_00920 4.24e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LHDOGKEF_00921 1e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_00922 8.01e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00923 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00924 5.63e-49 - - - - - - - -
LHDOGKEF_00925 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LHDOGKEF_00926 9.26e-222 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHDOGKEF_00927 9.09e-164 - - - S - - - Protein of unknown function (DUF975)
LHDOGKEF_00928 2.86e-81 - - - - - - - -
LHDOGKEF_00929 3.4e-228 pbpX2 - - V - - - Beta-lactamase
LHDOGKEF_00930 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LHDOGKEF_00931 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHDOGKEF_00932 3.35e-310 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LHDOGKEF_00933 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHDOGKEF_00934 2.17e-25 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LHDOGKEF_00935 2.18e-53 - - - - - - - -
LHDOGKEF_00936 8.03e-278 - - - S - - - Membrane
LHDOGKEF_00937 1.97e-107 ykuL - - S - - - (CBS) domain
LHDOGKEF_00938 0.0 cadA - - P - - - P-type ATPase
LHDOGKEF_00939 4.69e-262 napA - - P - - - Sodium/hydrogen exchanger family
LHDOGKEF_00940 2.82e-105 - - - S - - - Putative adhesin
LHDOGKEF_00941 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LHDOGKEF_00942 1.57e-197 mutR - - K - - - Helix-turn-helix XRE-family like proteins
LHDOGKEF_00943 5.7e-125 - - - M - - - CHAP domain
LHDOGKEF_00944 1.4e-88 - - - K - - - Helix-turn-helix XRE-family like proteins
LHDOGKEF_00945 2.41e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHDOGKEF_00946 3.39e-253 - - - S - - - DUF218 domain
LHDOGKEF_00947 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00948 4.51e-134 - - - S - - - ECF transporter, substrate-specific component
LHDOGKEF_00949 1.21e-236 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
LHDOGKEF_00950 9.41e-257 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
LHDOGKEF_00951 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
LHDOGKEF_00952 9.19e-266 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHDOGKEF_00953 4.74e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHDOGKEF_00954 1.25e-204 - - - S - - - Aldo/keto reductase family
LHDOGKEF_00955 1.19e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHDOGKEF_00956 1.63e-152 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LHDOGKEF_00957 6.91e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LHDOGKEF_00958 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
LHDOGKEF_00959 3.53e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHDOGKEF_00960 2.15e-21 - - - - - - - -
LHDOGKEF_00961 6.3e-91 - - - - - - - -
LHDOGKEF_00962 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LHDOGKEF_00963 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LHDOGKEF_00964 1.88e-292 yttB - - EGP - - - Major Facilitator
LHDOGKEF_00965 4.3e-297 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
LHDOGKEF_00966 1.6e-127 yitW - - S - - - Iron-sulfur cluster assembly protein
LHDOGKEF_00967 1.29e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHDOGKEF_00968 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LHDOGKEF_00969 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LHDOGKEF_00970 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHDOGKEF_00971 0.0 - - - S - - - Calcineurin-like phosphoesterase
LHDOGKEF_00972 3.65e-109 - - - - - - - -
LHDOGKEF_00973 7.66e-141 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LHDOGKEF_00974 6.38e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_00975 2.84e-171 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_00976 4.46e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LHDOGKEF_00977 7.56e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LHDOGKEF_00978 3.95e-113 usp5 - - T - - - universal stress protein
LHDOGKEF_00979 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LHDOGKEF_00980 1.74e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LHDOGKEF_00981 2.9e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
LHDOGKEF_00982 8.53e-292 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LHDOGKEF_00983 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
LHDOGKEF_00984 7.56e-205 - - - I - - - alpha/beta hydrolase fold
LHDOGKEF_00985 1.71e-170 yibF - - S - - - overlaps another CDS with the same product name
LHDOGKEF_00986 9.78e-258 yibE - - S - - - overlaps another CDS with the same product name
LHDOGKEF_00987 1.49e-136 - - - - - - - -
LHDOGKEF_00988 7.25e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LHDOGKEF_00989 1.96e-293 - - - S - - - Cysteine-rich secretory protein family
LHDOGKEF_00990 7.42e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_00991 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LHDOGKEF_00992 2.93e-173 - - - - - - - -
LHDOGKEF_00993 1.19e-160 - - - K - - - Bacterial regulatory proteins, tetR family
LHDOGKEF_00994 1.51e-234 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHDOGKEF_00995 1.3e-99 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
LHDOGKEF_00996 2.83e-62 - - - - - - - -
LHDOGKEF_00997 8.71e-157 - - - - - - - -
LHDOGKEF_00998 4.27e-293 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LHDOGKEF_00999 1.84e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
LHDOGKEF_01000 1.4e-180 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LHDOGKEF_01001 1e-305 - - - E - - - amino acid
LHDOGKEF_01002 1.27e-70 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
LHDOGKEF_01003 1.75e-10 - - - - - - - -
LHDOGKEF_01004 6.09e-152 - - - K - - - Rhodanese Homology Domain
LHDOGKEF_01005 1.23e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHDOGKEF_01006 6.65e-153 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
LHDOGKEF_01007 4.6e-249 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LHDOGKEF_01008 1.69e-259 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
LHDOGKEF_01011 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHDOGKEF_01012 9.21e-120 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHDOGKEF_01013 4.9e-33 - - - - - - - -
LHDOGKEF_01014 1.25e-147 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LHDOGKEF_01015 3.83e-167 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
LHDOGKEF_01016 9.31e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHDOGKEF_01017 2.15e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHDOGKEF_01018 1.86e-38 - - - - - - - -
LHDOGKEF_01019 3.62e-268 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LHDOGKEF_01020 1.74e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LHDOGKEF_01021 5.67e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHDOGKEF_01022 4.47e-186 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHDOGKEF_01023 4.47e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LHDOGKEF_01024 1.8e-223 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LHDOGKEF_01025 2.83e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LHDOGKEF_01026 1.5e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHDOGKEF_01027 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHDOGKEF_01028 3.66e-132 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LHDOGKEF_01029 1.72e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LHDOGKEF_01030 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LHDOGKEF_01031 1.22e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
LHDOGKEF_01032 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LHDOGKEF_01033 6.48e-148 - - - - - - - -
LHDOGKEF_01034 2.41e-45 - - - - - - - -
LHDOGKEF_01035 2.91e-121 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LHDOGKEF_01036 4.31e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHDOGKEF_01037 6.01e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LHDOGKEF_01038 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHDOGKEF_01039 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHDOGKEF_01040 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHDOGKEF_01041 1.82e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LHDOGKEF_01042 9.95e-70 - - - - - - - -
LHDOGKEF_01043 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LHDOGKEF_01044 9.84e-236 - - - S - - - AAA domain
LHDOGKEF_01045 1.27e-104 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHDOGKEF_01046 1.14e-27 - - - - - - - -
LHDOGKEF_01047 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LHDOGKEF_01048 6.91e-164 - - - G - - - Belongs to the phosphoglycerate mutase family
LHDOGKEF_01049 8.09e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
LHDOGKEF_01050 4.67e-154 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHDOGKEF_01051 3.63e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LHDOGKEF_01052 5.27e-16 - - - - - - - -
LHDOGKEF_01054 1.53e-85 - - - S - - - YjcQ protein
LHDOGKEF_01055 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
LHDOGKEF_01057 1.48e-69 - - - - - - - -
LHDOGKEF_01058 2.52e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LHDOGKEF_01059 1.77e-61 - - - - - - - -
LHDOGKEF_01060 1.31e-270 - - - EP - - - Plasmid replication protein
LHDOGKEF_01061 4.24e-37 - - - - - - - -
LHDOGKEF_01062 7.71e-255 - - - L - - - Phage integrase family
LHDOGKEF_01063 8.28e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LHDOGKEF_01064 1.6e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHDOGKEF_01065 4.17e-192 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHDOGKEF_01066 1.74e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHDOGKEF_01067 4.04e-206 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHDOGKEF_01068 4.16e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHDOGKEF_01069 1.57e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LHDOGKEF_01070 2.55e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDOGKEF_01071 3.95e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHDOGKEF_01072 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHDOGKEF_01073 4.63e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LHDOGKEF_01074 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHDOGKEF_01075 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LHDOGKEF_01076 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHDOGKEF_01077 2.45e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LHDOGKEF_01078 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LHDOGKEF_01079 5.3e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHDOGKEF_01080 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHDOGKEF_01081 2.5e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHDOGKEF_01082 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHDOGKEF_01083 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHDOGKEF_01084 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHDOGKEF_01085 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHDOGKEF_01086 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHDOGKEF_01087 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHDOGKEF_01088 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LHDOGKEF_01089 9.64e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHDOGKEF_01090 7.15e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHDOGKEF_01091 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHDOGKEF_01092 1.34e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHDOGKEF_01093 9.85e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHDOGKEF_01094 3.57e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHDOGKEF_01095 1.91e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LHDOGKEF_01096 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHDOGKEF_01097 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LHDOGKEF_01098 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHDOGKEF_01099 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHDOGKEF_01100 2.09e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHDOGKEF_01101 6.6e-159 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LHDOGKEF_01102 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDOGKEF_01103 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHDOGKEF_01104 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LHDOGKEF_01105 1.16e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LHDOGKEF_01109 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LHDOGKEF_01110 3.5e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHDOGKEF_01111 6.77e-215 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHDOGKEF_01112 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHDOGKEF_01113 5.11e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHDOGKEF_01114 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
LHDOGKEF_01115 1.03e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LHDOGKEF_01116 1.79e-46 yabO - - J - - - S4 domain protein
LHDOGKEF_01117 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHDOGKEF_01118 6.58e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHDOGKEF_01119 1.98e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHDOGKEF_01120 1.23e-166 - - - S - - - (CBS) domain
LHDOGKEF_01121 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHDOGKEF_01122 3.27e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHDOGKEF_01123 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LHDOGKEF_01124 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHDOGKEF_01125 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LHDOGKEF_01126 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
LHDOGKEF_01127 9.8e-204 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHDOGKEF_01128 0.0 - - - E - - - amino acid
LHDOGKEF_01129 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LHDOGKEF_01130 4.88e-59 - - - - - - - -
LHDOGKEF_01131 8.2e-68 - - - - - - - -
LHDOGKEF_01132 7.47e-126 - - - - - - - -
LHDOGKEF_01133 4.62e-13 - - - P - - - Voltage gated chloride channel
LHDOGKEF_01134 6.74e-39 - - - K ko:K12410 - ko00000,ko01000 NAD+ binding
LHDOGKEF_01135 3.18e-106 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHDOGKEF_01136 5.49e-42 - - - - - - - -
LHDOGKEF_01137 2.89e-44 - - - P - - - Belongs to the major facilitator superfamily
LHDOGKEF_01138 2.07e-117 - - - P - - - Belongs to the major facilitator superfamily
LHDOGKEF_01139 9.09e-173 XK27_07210 - - S - - - B3 4 domain
LHDOGKEF_01140 7.88e-116 - - - K - - - Acetyltransferase (GNAT) domain
LHDOGKEF_01141 1.16e-63 - - - S - - - Protein of unknown function (DUF3021)
LHDOGKEF_01142 1.03e-96 - - - K - - - LytTr DNA-binding domain
LHDOGKEF_01143 3.12e-191 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LHDOGKEF_01144 7.77e-199 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_01145 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LHDOGKEF_01146 3.77e-220 - - - K - - - Helix-turn-helix
LHDOGKEF_01147 1.04e-173 - - - K - - - DNA-binding helix-turn-helix protein
LHDOGKEF_01148 5.8e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHDOGKEF_01149 1.21e-285 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LHDOGKEF_01150 1.87e-137 ybbB - - S - - - Protein of unknown function (DUF1211)
LHDOGKEF_01151 7.87e-207 msmR - - K - - - AraC-like ligand binding domain
LHDOGKEF_01152 1.59e-205 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_01153 4.42e-142 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_01154 6.32e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHDOGKEF_01155 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHDOGKEF_01156 1.11e-96 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LHDOGKEF_01157 4.39e-88 - - - S - - - Domain of unknown function (DUF1934)
LHDOGKEF_01158 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHDOGKEF_01159 4.88e-59 - - - - - - - -
LHDOGKEF_01160 4.58e-216 - - - GK - - - ROK family
LHDOGKEF_01161 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_01162 3.82e-167 yecA - - K - - - Helix-turn-helix domain, rpiR family
LHDOGKEF_01163 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_01164 6.58e-227 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHDOGKEF_01165 0.0 - - - S - - - SLAP domain
LHDOGKEF_01166 1.48e-114 - - - - - - - -
LHDOGKEF_01167 4.55e-117 - - - S - - - SLAP domain
LHDOGKEF_01168 1.4e-116 - - - S - - - SLAP domain
LHDOGKEF_01169 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHDOGKEF_01170 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LHDOGKEF_01171 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
LHDOGKEF_01172 4.9e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHDOGKEF_01173 1.63e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LHDOGKEF_01174 2.33e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LHDOGKEF_01175 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHDOGKEF_01176 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
LHDOGKEF_01177 1.25e-142 - - - S ko:K06872 - ko00000 TPM domain
LHDOGKEF_01178 2.69e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
LHDOGKEF_01179 2.35e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHDOGKEF_01180 1.21e-146 - - - E - - - Belongs to the SOS response-associated peptidase family
LHDOGKEF_01182 1.09e-148 - - - - - - - -
LHDOGKEF_01183 6.92e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHDOGKEF_01184 1.5e-96 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHDOGKEF_01185 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LHDOGKEF_01186 1.87e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01187 1.9e-256 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01188 1.92e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHDOGKEF_01189 5.46e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHDOGKEF_01190 8.86e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHDOGKEF_01191 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LHDOGKEF_01192 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LHDOGKEF_01193 1.16e-162 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHDOGKEF_01194 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LHDOGKEF_01196 1.02e-74 - - - - - - - -
LHDOGKEF_01197 6.28e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHDOGKEF_01198 0.0 - - - S - - - Fibronectin type III domain
LHDOGKEF_01199 0.0 XK27_08315 - - M - - - Sulfatase
LHDOGKEF_01200 2.73e-146 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHDOGKEF_01201 1.34e-259 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LHDOGKEF_01202 1.96e-132 - - - G - - - Aldose 1-epimerase
LHDOGKEF_01203 8.51e-143 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LHDOGKEF_01204 1.84e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHDOGKEF_01205 2.12e-176 - - - - - - - -
LHDOGKEF_01206 4.62e-181 - - - - - - - -
LHDOGKEF_01207 6.61e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LHDOGKEF_01208 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LHDOGKEF_01209 7.59e-269 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
LHDOGKEF_01210 2.53e-283 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHDOGKEF_01212 2.84e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHDOGKEF_01213 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHDOGKEF_01214 1.14e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHDOGKEF_01215 6.33e-74 - - - - - - - -
LHDOGKEF_01216 7.08e-137 - - - - - - - -
LHDOGKEF_01217 1.41e-209 yicL - - EG - - - EamA-like transporter family
LHDOGKEF_01218 1.03e-211 - - - EG - - - EamA-like transporter family
LHDOGKEF_01219 8.16e-212 - - - EG - - - EamA-like transporter family
LHDOGKEF_01220 1.96e-108 - - - M - - - NlpC/P60 family
LHDOGKEF_01221 1.91e-171 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LHDOGKEF_01222 9.67e-220 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LHDOGKEF_01223 1.23e-83 - - - S - - - Protein conserved in bacteria
LHDOGKEF_01224 6.65e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHDOGKEF_01225 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LHDOGKEF_01226 1.06e-20 - - - - - - - -
LHDOGKEF_01227 4.8e-99 - - - - - - - -
LHDOGKEF_01228 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LHDOGKEF_01229 7.79e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LHDOGKEF_01230 7.43e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
LHDOGKEF_01231 1.82e-276 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHDOGKEF_01232 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LHDOGKEF_01233 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LHDOGKEF_01234 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LHDOGKEF_01235 1.23e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LHDOGKEF_01236 1.98e-26 - - - - - - - -
LHDOGKEF_01237 1.09e-157 - - - - - - - -
LHDOGKEF_01238 8e-226 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LHDOGKEF_01239 6.92e-130 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LHDOGKEF_01240 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01241 2.11e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
LHDOGKEF_01242 9.9e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LHDOGKEF_01243 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
LHDOGKEF_01244 3.36e-249 ysdE - - P - - - Citrate transporter
LHDOGKEF_01245 7.83e-91 - - - S - - - Iron-sulphur cluster biosynthesis
LHDOGKEF_01246 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
LHDOGKEF_01247 9.69e-25 - - - - - - - -
LHDOGKEF_01248 2.14e-197 - - - - - - - -
LHDOGKEF_01250 1.08e-288 ydaM - - M - - - Glycosyl transferase family group 2
LHDOGKEF_01251 2.11e-271 - - - G - - - Glycosyl hydrolases family 8
LHDOGKEF_01252 1.07e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LHDOGKEF_01253 2.73e-206 - - - L - - - HNH nucleases
LHDOGKEF_01254 1.63e-233 yhaH - - S - - - Protein of unknown function (DUF805)
LHDOGKEF_01255 2.21e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01256 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01257 3.08e-159 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LHDOGKEF_01258 2.29e-85 yeaO - - S - - - Protein of unknown function, DUF488
LHDOGKEF_01259 9.33e-180 terC - - P - - - Integral membrane protein TerC family
LHDOGKEF_01260 2.57e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
LHDOGKEF_01261 9.36e-111 - - - - - - - -
LHDOGKEF_01262 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHDOGKEF_01263 1.45e-231 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LHDOGKEF_01264 2.82e-183 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHDOGKEF_01265 5.06e-182 - - - S - - - Protein of unknown function (DUF1002)
LHDOGKEF_01266 2.63e-204 - - - M - - - Glycosyltransferase like family 2
LHDOGKEF_01267 1.07e-163 - - - S - - - Alpha/beta hydrolase family
LHDOGKEF_01268 1.02e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
LHDOGKEF_01269 1.33e-75 - - - - - - - -
LHDOGKEF_01270 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_01271 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
LHDOGKEF_01272 8.36e-102 - - - - - - - -
LHDOGKEF_01273 1.11e-191 - - - I - - - Acyl-transferase
LHDOGKEF_01274 6.45e-204 arbx - - M - - - Glycosyl transferase family 8
LHDOGKEF_01275 1.07e-238 - - - M - - - Glycosyl transferase family 8
LHDOGKEF_01276 1.34e-235 - - - M - - - Glycosyl transferase family 8
LHDOGKEF_01277 2.27e-214 arbZ - - I - - - Phosphate acyltransferases
LHDOGKEF_01278 2.5e-51 - - - S - - - Cytochrome B5
LHDOGKEF_01279 3.17e-149 - - - K - - - Transcriptional regulator, LysR family
LHDOGKEF_01280 1.87e-292 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LHDOGKEF_01281 4.38e-74 - - - S - - - FMN_bind
LHDOGKEF_01282 3.73e-65 - - - K - - - LysR substrate binding domain
LHDOGKEF_01283 9.97e-103 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
LHDOGKEF_01284 4.63e-225 - - - I - - - alpha/beta hydrolase fold
LHDOGKEF_01285 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_01286 5.47e-199 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LHDOGKEF_01287 0.0 - - - G - - - Protein of unknown function (DUF4038)
LHDOGKEF_01288 1.05e-225 - - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
LHDOGKEF_01289 8.27e-190 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHDOGKEF_01290 2.7e-10 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHDOGKEF_01291 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHDOGKEF_01292 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LHDOGKEF_01293 1.11e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHDOGKEF_01294 0.0 - - - G - - - isomerase
LHDOGKEF_01295 1.46e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHDOGKEF_01296 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
LHDOGKEF_01297 8.15e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
LHDOGKEF_01298 1.79e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LHDOGKEF_01299 0.0 - - - S - - - Domain of unknown function (DUF5060)
LHDOGKEF_01300 1.05e-274 - - - EGP - - - Transporter, major facilitator family protein
LHDOGKEF_01301 2.88e-223 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LHDOGKEF_01302 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
LHDOGKEF_01303 2e-79 - - - G - - - polysaccharide catabolic process
LHDOGKEF_01325 2.24e-284 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
LHDOGKEF_01326 1.5e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LHDOGKEF_01327 5.18e-228 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHDOGKEF_01328 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LHDOGKEF_01329 5.29e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LHDOGKEF_01330 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LHDOGKEF_01331 1.99e-99 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LHDOGKEF_01332 2.3e-229 - - - - - - - -
LHDOGKEF_01333 0.0 icaA - - M - - - Glycosyl transferase family group 2
LHDOGKEF_01334 4.97e-81 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LHDOGKEF_01335 1.49e-58 - - - S - - - SLAP domain
LHDOGKEF_01338 9.77e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LHDOGKEF_01339 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHDOGKEF_01340 0.0 yycH - - S - - - YycH protein
LHDOGKEF_01341 3.54e-190 yycI - - S - - - YycH protein
LHDOGKEF_01342 9.1e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LHDOGKEF_01343 2.7e-257 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LHDOGKEF_01344 2.48e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHDOGKEF_01345 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHDOGKEF_01346 3.62e-121 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LHDOGKEF_01347 4.92e-207 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LHDOGKEF_01348 1.84e-196 - - - I - - - alpha/beta hydrolase fold
LHDOGKEF_01349 1.47e-144 - - - S - - - SNARE associated Golgi protein
LHDOGKEF_01350 1.28e-131 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHDOGKEF_01351 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHDOGKEF_01352 3.27e-294 - - - E ko:K03294 - ko00000 amino acid
LHDOGKEF_01353 9.79e-168 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHDOGKEF_01354 2.35e-269 yfmL - - L - - - DEAD DEAH box helicase
LHDOGKEF_01355 5.88e-312 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_01357 3.83e-61 - - - L - - - Helicase C-terminal domain protein
LHDOGKEF_01358 0.0 - - - L - - - Helicase C-terminal domain protein
LHDOGKEF_01359 1.98e-96 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LHDOGKEF_01362 0.0 - - - S - - - CAAX protease self-immunity
LHDOGKEF_01364 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LHDOGKEF_01365 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LHDOGKEF_01366 1.51e-145 - - - - - - - -
LHDOGKEF_01367 9.91e-241 - - - M - - - domain protein
LHDOGKEF_01368 7.5e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LHDOGKEF_01369 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LHDOGKEF_01370 6.76e-247 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LHDOGKEF_01371 1.42e-215 - - - S - - - SLAP domain
LHDOGKEF_01372 3.46e-53 - - - C - - - FMN binding
LHDOGKEF_01374 1.53e-61 - - - - - - - -
LHDOGKEF_01375 9.46e-67 - - - S - - - Domain of unknown function (DUF4160)
LHDOGKEF_01376 4.02e-124 - - - S - - - Domain of unknown function (DUF4811)
LHDOGKEF_01377 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LHDOGKEF_01378 2.78e-98 - - - K - - - MerR HTH family regulatory protein
LHDOGKEF_01379 7.27e-206 lacR - - K - - - helix_turn_helix, arabinose operon control protein
LHDOGKEF_01380 6.26e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHDOGKEF_01381 1.98e-200 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01382 3.56e-196 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01383 3.33e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01384 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LHDOGKEF_01385 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
LHDOGKEF_01386 1.63e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LHDOGKEF_01387 8.2e-81 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LHDOGKEF_01388 1.31e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LHDOGKEF_01389 7.55e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LHDOGKEF_01390 4.2e-147 - - - T - - - Region found in RelA / SpoT proteins
LHDOGKEF_01391 1.28e-152 dltr - - K - - - response regulator
LHDOGKEF_01392 9.45e-298 sptS - - T - - - Histidine kinase
LHDOGKEF_01393 3.65e-272 - - - EGP - - - Major Facilitator Superfamily
LHDOGKEF_01394 8.84e-93 - - - O - - - OsmC-like protein
LHDOGKEF_01395 5.44e-163 - - - S - - - L-ascorbic acid biosynthetic process
LHDOGKEF_01396 1.31e-165 - - - - - - - -
LHDOGKEF_01398 2.05e-163 - - - S - - - Alpha beta hydrolase
LHDOGKEF_01399 0.0 potE - - E - - - Amino Acid
LHDOGKEF_01400 2.86e-19 - - - - - - - -
LHDOGKEF_01401 4.83e-141 pncA - - Q - - - Isochorismatase family
LHDOGKEF_01402 4.27e-37 - - - C - - - pentaerythritol trinitrate reductase activity
LHDOGKEF_01403 4.69e-271 - - - L ko:K07496 - ko00000 TIGRFAM transposase, IS605 OrfB family
LHDOGKEF_01405 9.37e-227 - - - C - - - Oxidoreductase
LHDOGKEF_01406 3.07e-119 - - - - - - - -
LHDOGKEF_01407 8.31e-313 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
LHDOGKEF_01408 8.74e-192 - - - T - - - EAL domain
LHDOGKEF_01409 1.63e-169 - - - T - - - Putative diguanylate phosphodiesterase
LHDOGKEF_01410 2.26e-267 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
LHDOGKEF_01413 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
LHDOGKEF_01414 1.3e-206 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
LHDOGKEF_01416 6.71e-153 - - - S - - - GyrI-like small molecule binding domain
LHDOGKEF_01417 1.08e-85 - - - S - - - ASCH domain
LHDOGKEF_01418 2.97e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LHDOGKEF_01419 1.45e-149 ylbE - - GM - - - NAD(P)H-binding
LHDOGKEF_01420 3.88e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LHDOGKEF_01421 7.81e-82 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
LHDOGKEF_01422 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LHDOGKEF_01424 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_01425 2.66e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
LHDOGKEF_01426 1.15e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LHDOGKEF_01427 7.22e-161 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LHDOGKEF_01428 2.87e-62 - - - - - - - -
LHDOGKEF_01429 2.34e-204 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHDOGKEF_01430 1.65e-66 - - - - - - - -
LHDOGKEF_01431 3.89e-122 - - - K - - - acetyltransferase
LHDOGKEF_01432 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHDOGKEF_01433 1.86e-141 - - - O - - - Matrixin
LHDOGKEF_01434 9.28e-317 eriC - - P ko:K03281 - ko00000 chloride
LHDOGKEF_01435 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LHDOGKEF_01436 3.3e-152 - - - GM - - - NmrA-like family
LHDOGKEF_01437 2.73e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHDOGKEF_01438 7.44e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LHDOGKEF_01439 1.94e-215 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHDOGKEF_01440 1.75e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHDOGKEF_01441 3.43e-235 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LHDOGKEF_01442 5.02e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHDOGKEF_01443 2.85e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHDOGKEF_01444 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LHDOGKEF_01445 2.73e-07 - - - D - - - Domain of Unknown Function (DUF1542)
LHDOGKEF_01446 0.0 - - - - - - - -
LHDOGKEF_01447 1.74e-192 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LHDOGKEF_01448 2.43e-62 - - - - - - - -
LHDOGKEF_01449 1.67e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LHDOGKEF_01450 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LHDOGKEF_01451 2.45e-63 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
LHDOGKEF_01452 1.02e-85 - - - K - - - sequence-specific DNA binding
LHDOGKEF_01453 3.5e-22 - - - - - - - -
LHDOGKEF_01454 9.35e-128 - - - S - - - Bacterial PH domain
LHDOGKEF_01455 4.19e-302 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_01456 3.58e-262 xylR - - GK - - - ROK family
LHDOGKEF_01457 7.89e-213 - 2.7.1.85 - GK ko:K18673 - ko00000,ko01000 ROK family
LHDOGKEF_01458 0.0 - 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_01459 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
LHDOGKEF_01460 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LHDOGKEF_01461 1.71e-211 - - - - - - - -
LHDOGKEF_01462 1.64e-262 - - - - - - - -
LHDOGKEF_01463 1.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
LHDOGKEF_01464 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_01465 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_01466 4.8e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LHDOGKEF_01467 1.75e-227 lipA - - I - - - Carboxylesterase family
LHDOGKEF_01468 4.22e-211 - - - S - - - Membrane
LHDOGKEF_01470 1.75e-95 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHDOGKEF_01471 1.16e-162 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHDOGKEF_01472 3.04e-198 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
LHDOGKEF_01473 0.0 - - - S - - - Predicted membrane protein (DUF2207)
LHDOGKEF_01474 3.88e-196 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
LHDOGKEF_01475 7.38e-127 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_01476 9.58e-80 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_01477 7.45e-09 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_01478 9.64e-141 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LHDOGKEF_01479 4.41e-137 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LHDOGKEF_01480 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LHDOGKEF_01481 3.98e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LHDOGKEF_01482 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LHDOGKEF_01483 3.54e-192 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHDOGKEF_01484 4.8e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LHDOGKEF_01485 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LHDOGKEF_01486 3.69e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LHDOGKEF_01487 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHDOGKEF_01488 2.57e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LHDOGKEF_01489 1.28e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHDOGKEF_01490 5.91e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHDOGKEF_01491 5.86e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHDOGKEF_01492 3.76e-48 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHDOGKEF_01493 1.84e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHDOGKEF_01494 1.52e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LHDOGKEF_01495 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LHDOGKEF_01496 2.88e-105 - - - S - - - ASCH
LHDOGKEF_01497 2.53e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LHDOGKEF_01498 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LHDOGKEF_01499 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHDOGKEF_01500 1.08e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHDOGKEF_01501 4.61e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LHDOGKEF_01502 9.79e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LHDOGKEF_01503 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHDOGKEF_01504 1.37e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LHDOGKEF_01505 5.27e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LHDOGKEF_01506 3.29e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LHDOGKEF_01507 1.5e-68 - - - - - - - -
LHDOGKEF_01508 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LHDOGKEF_01509 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
LHDOGKEF_01510 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LHDOGKEF_01511 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHDOGKEF_01512 3.16e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LHDOGKEF_01513 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHDOGKEF_01514 1.43e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01515 8.73e-234 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01516 1.28e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01517 5.84e-202 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01518 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_01519 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_01520 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LHDOGKEF_01521 0.0 yhdP - - S - - - Transporter associated domain
LHDOGKEF_01522 9.09e-156 - - - C - - - nitroreductase
LHDOGKEF_01523 1.51e-53 - - - - - - - -
LHDOGKEF_01524 5.61e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LHDOGKEF_01525 2.25e-105 - - - - - - - -
LHDOGKEF_01526 1.1e-191 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LHDOGKEF_01527 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LHDOGKEF_01528 1.35e-196 - - - S - - - hydrolase
LHDOGKEF_01529 5.93e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHDOGKEF_01530 8.04e-187 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LHDOGKEF_01531 7.37e-293 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LHDOGKEF_01532 2.25e-206 - - - S - - - Phospholipase, patatin family
LHDOGKEF_01533 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LHDOGKEF_01534 3.4e-178 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LHDOGKEF_01535 7.73e-79 - - - S - - - Enterocin A Immunity
LHDOGKEF_01536 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LHDOGKEF_01537 1.21e-93 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
LHDOGKEF_01538 2.07e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LHDOGKEF_01539 0.0 - - - V - - - ABC transporter transmembrane region
LHDOGKEF_01540 5.7e-146 - - - - - - - -
LHDOGKEF_01541 1.81e-28 - - - - - - - -
LHDOGKEF_01542 1.98e-175 gntR - - K - - - UbiC transcription regulator-associated domain protein
LHDOGKEF_01543 3.51e-223 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
LHDOGKEF_01544 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LHDOGKEF_01545 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LHDOGKEF_01546 9.2e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHDOGKEF_01547 5.34e-211 - - - C - - - Domain of unknown function (DUF4931)
LHDOGKEF_01548 5.02e-313 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHDOGKEF_01549 2.75e-95 - - - - - - - -
LHDOGKEF_01550 3.66e-224 - - - S - - - Protein of unknown function (DUF2974)
LHDOGKEF_01551 8.28e-143 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01552 1.43e-136 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01553 4.3e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_01554 2.39e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01555 1.92e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
LHDOGKEF_01556 8.88e-132 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LHDOGKEF_01557 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
LHDOGKEF_01558 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01559 6.57e-102 - - - K - - - Transcriptional regulator, MarR family
LHDOGKEF_01560 2.22e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHDOGKEF_01561 1.4e-188 - - - - - - - -
LHDOGKEF_01562 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LHDOGKEF_01563 7.56e-267 pepA - - E - - - M42 glutamyl aminopeptidase
LHDOGKEF_01564 1.11e-212 - - - S ko:K07088 - ko00000 Membrane transport protein
LHDOGKEF_01565 3.81e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
LHDOGKEF_01566 0.0 qacA - - EGP - - - Major Facilitator
LHDOGKEF_01567 2.03e-67 - 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
LHDOGKEF_01568 3.27e-110 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHDOGKEF_01569 1.39e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHDOGKEF_01570 5.36e-305 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LHDOGKEF_01571 5.81e-165 XK27_08575 - - V ko:K06148 - ko00000,ko02000 cysteine transport
LHDOGKEF_01572 5.13e-141 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LHDOGKEF_01573 4.73e-206 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LHDOGKEF_01574 3.79e-101 - - - K - - - acetyltransferase
LHDOGKEF_01575 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LHDOGKEF_01576 1.25e-118 - - - K - - - Bacterial regulatory proteins, tetR family
LHDOGKEF_01577 1.88e-174 - - - S - - - CAAX protease self-immunity
LHDOGKEF_01578 0.0 qacA - - EGP - - - Major Facilitator
LHDOGKEF_01583 3.49e-123 - - - K - - - Acetyltransferase (GNAT) domain
LHDOGKEF_01584 9.05e-231 - - - L - - - Recombinase zinc beta ribbon domain
LHDOGKEF_01585 3.28e-122 - - - L - - - Resolvase, N terminal domain
LHDOGKEF_01586 2.98e-246 - - - L ko:K06400 - ko00000 Recombinase
LHDOGKEF_01587 2.43e-76 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
LHDOGKEF_01588 3.15e-62 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
LHDOGKEF_01589 5.16e-146 ung2 - - L - - - Uracil-DNA glycosylase
LHDOGKEF_01590 9.1e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
LHDOGKEF_01591 1.05e-124 dpsB - - P - - - Belongs to the Dps family
LHDOGKEF_01592 5.51e-46 - - - C - - - Heavy-metal-associated domain
LHDOGKEF_01593 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LHDOGKEF_01594 1.48e-82 - - - - - - - -
LHDOGKEF_01595 4.2e-30 - - - - - - - -
LHDOGKEF_01596 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHDOGKEF_01597 1.28e-310 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LHDOGKEF_01598 4.94e-75 - - - - - - - -
LHDOGKEF_01599 8.38e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LHDOGKEF_01600 2.37e-220 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LHDOGKEF_01601 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHDOGKEF_01602 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LHDOGKEF_01603 4.46e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHDOGKEF_01604 7.29e-267 camS - - S - - - sex pheromone
LHDOGKEF_01605 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHDOGKEF_01606 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LHDOGKEF_01607 1.02e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LHDOGKEF_01609 6.32e-83 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LHDOGKEF_01610 8.44e-177 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LHDOGKEF_01611 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LHDOGKEF_01612 3.89e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LHDOGKEF_01613 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LHDOGKEF_01614 5.7e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LHDOGKEF_01615 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHDOGKEF_01616 1.85e-264 - - - M - - - Glycosyl transferases group 1
LHDOGKEF_01617 1.39e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LHDOGKEF_01618 2.13e-92 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
LHDOGKEF_01619 1.33e-160 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
LHDOGKEF_01620 5.81e-272 - - - - - - - -
LHDOGKEF_01623 0.0 slpX - - S - - - SLAP domain
LHDOGKEF_01624 6.76e-227 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LHDOGKEF_01626 3.18e-92 - - - EGP - - - Major Facilitator
LHDOGKEF_01627 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
LHDOGKEF_01628 8.89e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01629 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
LHDOGKEF_01630 2.93e-199 msmG - - G ko:K02026,ko:K10122 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01631 1.78e-209 - - - P ko:K10121 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
LHDOGKEF_01632 0.0 - - - G ko:K02027,ko:K10120 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHDOGKEF_01633 7.11e-236 lacI - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LHDOGKEF_01634 9.11e-69 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHDOGKEF_01635 9.82e-156 - - - G - - - Antibiotic biosynthesis monooxygenase
LHDOGKEF_01636 2.57e-139 - - - G - - - Histidine phosphatase superfamily (branch 1)
LHDOGKEF_01637 1e-142 - - - G - - - Phosphoglycerate mutase family
LHDOGKEF_01638 3.81e-253 - - - D - - - nuclear chromosome segregation
LHDOGKEF_01639 2.62e-111 - - - M - - - LysM domain protein
LHDOGKEF_01640 4.35e-207 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LHDOGKEF_01641 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHDOGKEF_01642 2.6e-19 - - - - - - - -
LHDOGKEF_01643 1.48e-219 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
LHDOGKEF_01644 3.99e-88 - - - - - - - -
LHDOGKEF_01645 3.99e-45 - - - - - - - -
LHDOGKEF_01646 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
LHDOGKEF_01647 2.79e-296 - - - L - - - Belongs to the 'phage' integrase family
LHDOGKEF_01648 6.89e-06 - - - - - - - -
LHDOGKEF_01649 3.69e-244 - - - EP - - - Plasmid replication protein
LHDOGKEF_01651 2.66e-270 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LHDOGKEF_01652 8.66e-76 - - - - - - - -
LHDOGKEF_01654 8.37e-161 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
LHDOGKEF_01655 1.41e-208 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
LHDOGKEF_01656 0.0 - - - S - - - AAA ATPase domain
LHDOGKEF_01657 0.0 - - - L - - - Type III restriction enzyme, res subunit
LHDOGKEF_01659 8.42e-187 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LHDOGKEF_01660 1.14e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LHDOGKEF_01661 4.47e-81 - - - - - - - -
LHDOGKEF_01662 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
LHDOGKEF_01663 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
LHDOGKEF_01664 0.0 - - - S - - - TerB-C domain
LHDOGKEF_01665 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LHDOGKEF_01666 8.15e-94 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
LHDOGKEF_01667 1.63e-175 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LHDOGKEF_01668 1.47e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHDOGKEF_01669 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHDOGKEF_01670 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LHDOGKEF_01671 2.27e-315 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LHDOGKEF_01672 3.62e-89 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LHDOGKEF_01673 7.93e-206 - - - K - - - Transcriptional regulator
LHDOGKEF_01674 2.86e-85 - - - S - - - Domain of unknown function (DUF956)
LHDOGKEF_01675 1.18e-225 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LHDOGKEF_01676 1.67e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LHDOGKEF_01677 1.36e-241 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LHDOGKEF_01678 6e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHDOGKEF_01679 1.35e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHDOGKEF_01680 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01681 8.05e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01682 2.56e-110 - - - - - - - -
LHDOGKEF_01683 2.49e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
LHDOGKEF_01686 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
LHDOGKEF_01687 1.53e-118 ymdB - - S - - - Macro domain protein
LHDOGKEF_01688 1.97e-280 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
LHDOGKEF_01690 8.59e-148 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LHDOGKEF_01691 3e-133 - - - EGP - - - Major Facilitator Superfamily
LHDOGKEF_01692 9.68e-226 - - - - - - - -
LHDOGKEF_01693 7.67e-80 lysM - - M - - - LysM domain
LHDOGKEF_01694 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LHDOGKEF_01695 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LHDOGKEF_01696 2.13e-36 - - - - - - - -
LHDOGKEF_01697 1.71e-282 - - - S - - - Putative peptidoglycan binding domain
LHDOGKEF_01698 3.08e-204 - - - C - - - Domain of unknown function (DUF4931)
LHDOGKEF_01699 3.44e-153 - - - - - - - -
LHDOGKEF_01700 4.33e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LHDOGKEF_01701 1.19e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
LHDOGKEF_01702 9.98e-146 - - - G - - - phosphoglycerate mutase
LHDOGKEF_01703 5.93e-124 - - - K - - - Bacterial regulatory proteins, tetR family
LHDOGKEF_01704 1.43e-231 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01705 3.26e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01706 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_01707 2e-26 - - - - - - - -
LHDOGKEF_01708 1.25e-143 - - - K - - - WHG domain
LHDOGKEF_01709 4.14e-126 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LHDOGKEF_01710 6.34e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LHDOGKEF_01711 9.1e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LHDOGKEF_01712 6.64e-233 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LHDOGKEF_01713 8.5e-105 cvpA - - S - - - Colicin V production protein
LHDOGKEF_01714 3.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LHDOGKEF_01715 2.79e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHDOGKEF_01716 4.1e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LHDOGKEF_01717 2.05e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHDOGKEF_01718 2.22e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LHDOGKEF_01719 1.39e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHDOGKEF_01720 1.55e-177 - - - S - - - Protein of unknown function (DUF1129)
LHDOGKEF_01721 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01722 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LHDOGKEF_01723 1.44e-157 vanR - - K - - - response regulator
LHDOGKEF_01724 9.58e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
LHDOGKEF_01725 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHDOGKEF_01726 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LHDOGKEF_01727 5.63e-64 - - - S - - - Enterocin A Immunity
LHDOGKEF_01728 1.4e-69 - - - S - - - Enterocin A Immunity
LHDOGKEF_01729 1.47e-45 - - - - - - - -
LHDOGKEF_01730 9.17e-37 - - - - - - - -
LHDOGKEF_01731 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
LHDOGKEF_01732 2.62e-50 - - - S - - - Enterocin A Immunity
LHDOGKEF_01733 5.21e-275 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHDOGKEF_01734 2.71e-136 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHDOGKEF_01736 2.6e-141 - - - - - - - -
LHDOGKEF_01739 2e-06 - - - - - - - -
LHDOGKEF_01740 8.09e-298 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LHDOGKEF_01741 7.63e-190 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LHDOGKEF_01744 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHDOGKEF_01745 3.21e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LHDOGKEF_01746 1.21e-275 blpT - - - - - - -
LHDOGKEF_01751 2.26e-29 - - - - - - - -
LHDOGKEF_01752 9.7e-116 - - - - - - - -
LHDOGKEF_01753 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LHDOGKEF_01754 6.68e-35 - - - - - - - -
LHDOGKEF_01755 4.14e-89 - - - - - - - -
LHDOGKEF_01756 2.89e-12 - - - - - - - -
LHDOGKEF_01757 1.6e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01758 7.39e-276 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LHDOGKEF_01759 5.63e-253 - - - S - - - Fic/DOC family
LHDOGKEF_01760 3.67e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LHDOGKEF_01761 1.31e-216 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LHDOGKEF_01762 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LHDOGKEF_01763 4.7e-64 - - - S - - - Protein of unknown function (DUF3021)
LHDOGKEF_01764 3e-98 - - - K - - - LytTr DNA-binding domain
LHDOGKEF_01765 7.83e-60 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LHDOGKEF_01766 1.79e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHDOGKEF_01767 6.65e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHDOGKEF_01768 6.99e-174 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LHDOGKEF_01769 1.04e-82 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
LHDOGKEF_01770 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LHDOGKEF_01771 9.86e-59 - - - P ko:K03449 - ko00000,ko02000 transmembrane transport
LHDOGKEF_01772 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LHDOGKEF_01773 5.01e-293 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LHDOGKEF_01774 2.7e-59 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHDOGKEF_01775 3.08e-81 - - - - - - - -
LHDOGKEF_01776 0.0 - - - S - - - ABC transporter
LHDOGKEF_01777 3.8e-176 - - - S - - - Putative threonine/serine exporter
LHDOGKEF_01778 4.44e-110 - - - S - - - Threonine/Serine exporter, ThrE
LHDOGKEF_01779 1.64e-47 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LHDOGKEF_01780 1.08e-62 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LHDOGKEF_01781 1.47e-70 yitW - - S - - - Iron-sulfur cluster assembly protein
LHDOGKEF_01782 3.7e-175 - - - S - - - Peptidase_C39 like family
LHDOGKEF_01783 1.36e-105 - - - - - - - -
LHDOGKEF_01784 2.71e-233 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHDOGKEF_01785 7.02e-103 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
LHDOGKEF_01786 4.7e-143 - - - - - - - -
LHDOGKEF_01787 0.0 - - - S - - - O-antigen ligase like membrane protein
LHDOGKEF_01788 2.96e-56 - - - - - - - -
LHDOGKEF_01789 6.94e-110 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
LHDOGKEF_01790 7.09e-125 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
LHDOGKEF_01791 2.99e-176 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LHDOGKEF_01792 1.4e-204 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
LHDOGKEF_01793 0.0 - - - M - - - Mycoplasma protein of unknown function, DUF285
LHDOGKEF_01794 5.52e-241 - - - S - - - Cysteine-rich secretory protein family
LHDOGKEF_01795 1.42e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHDOGKEF_01796 5.44e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LHDOGKEF_01797 1.01e-193 epsB - - M - - - biosynthesis protein
LHDOGKEF_01798 5.93e-166 ywqD - - D - - - Capsular exopolysaccharide family
LHDOGKEF_01799 6.17e-191 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LHDOGKEF_01800 1.77e-159 epsE2 - - M - - - Bacterial sugar transferase
LHDOGKEF_01801 4.02e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
LHDOGKEF_01802 2.65e-215 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LHDOGKEF_01804 4.69e-158 - - - M - - - transferase activity, transferring glycosyl groups
LHDOGKEF_01805 7.58e-244 XK27_01805 - - M - - - Glycosyltransferase like family 2
LHDOGKEF_01806 1.86e-287 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
LHDOGKEF_01807 1.31e-93 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
LHDOGKEF_01808 7.05e-126 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LHDOGKEF_01809 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LHDOGKEF_01810 1.34e-298 - - - L - - - COG3547 Transposase and inactivated derivatives
LHDOGKEF_01811 1.63e-175 - - - L ko:K07483 - ko00000 transposase activity
LHDOGKEF_01812 2.52e-84 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LHDOGKEF_01813 1e-112 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHDOGKEF_01814 1.31e-211 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHDOGKEF_01821 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
LHDOGKEF_01822 6.91e-235 - - - - - - - -
LHDOGKEF_01823 4.05e-119 - - - - - - - -
LHDOGKEF_01824 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
LHDOGKEF_01826 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
LHDOGKEF_01827 4.37e-205 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LHDOGKEF_01828 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_01829 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHDOGKEF_01830 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHDOGKEF_01831 1.24e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LHDOGKEF_01832 1.06e-258 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
LHDOGKEF_01833 1.96e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
LHDOGKEF_01834 3.86e-239 - - - K - - - helix_turn_helix, arabinose operon control protein
LHDOGKEF_01835 7.86e-240 - - - K - - - helix_turn_helix, arabinose operon control protein
LHDOGKEF_01836 1.71e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHDOGKEF_01837 1.56e-256 - - - S - - - Membrane
LHDOGKEF_01838 5.59e-250 - - - S - - - Domain of unknown function (DUF4767)
LHDOGKEF_01839 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
LHDOGKEF_01840 0.0 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
LHDOGKEF_01843 3.39e-138 - - - K ko:K06977 - ko00000 acetyltransferase
LHDOGKEF_01844 1.6e-119 - - - - - - - -
LHDOGKEF_01845 8.44e-201 - - - - - - - -
LHDOGKEF_01846 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
LHDOGKEF_01847 7.07e-178 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LHDOGKEF_01848 1.35e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
LHDOGKEF_01849 1.25e-22 - - - - - - - -
LHDOGKEF_01850 3.45e-64 - - - - - - - -
LHDOGKEF_01851 3.66e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LHDOGKEF_01852 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LHDOGKEF_01853 1.39e-164 - - - - - - - -
LHDOGKEF_01854 7.62e-308 - - - S - - - response to antibiotic
LHDOGKEF_01855 3.02e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHDOGKEF_01856 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LHDOGKEF_01857 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
LHDOGKEF_01858 1.69e-160 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LHDOGKEF_01859 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHDOGKEF_01860 2.14e-31 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHDOGKEF_01861 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LHDOGKEF_01862 1.29e-140 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
LHDOGKEF_01863 2.71e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LHDOGKEF_01864 1.25e-106 yjcF - - S - - - Acetyltransferase (GNAT) domain
LHDOGKEF_01865 1.68e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHDOGKEF_01866 3.51e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LHDOGKEF_01867 8.57e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHDOGKEF_01868 9.2e-130 - - - S - - - Peptidase propeptide and YPEB domain
LHDOGKEF_01869 2.28e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LHDOGKEF_01870 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LHDOGKEF_01871 3.59e-123 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LHDOGKEF_01872 4.9e-100 yybA - - K - - - Transcriptional regulator
LHDOGKEF_01873 1.34e-131 - - - S - - - Peptidase propeptide and YPEB domain
LHDOGKEF_01874 2.36e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
LHDOGKEF_01875 4.14e-312 - - - T - - - GHKL domain
LHDOGKEF_01876 2.91e-164 - - - T - - - Transcriptional regulatory protein, C terminal
LHDOGKEF_01877 5.44e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LHDOGKEF_01878 0.0 - - - V - - - ABC transporter transmembrane region
LHDOGKEF_01879 9.1e-184 - - - S - - - PAS domain
LHDOGKEF_01880 7.95e-64 - - - - - - - -
LHDOGKEF_01881 0.0 - - - - - - - -
LHDOGKEF_01882 3.05e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LHDOGKEF_01883 0.0 - - - M - - - domain protein
LHDOGKEF_01884 9.54e-97 - - - S - - - Protein of unknown function (DUF3290)
LHDOGKEF_01885 7.21e-150 yviA - - S - - - Protein of unknown function (DUF421)
LHDOGKEF_01886 4.72e-200 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LHDOGKEF_01887 4e-234 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LHDOGKEF_01888 4.53e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LHDOGKEF_01889 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHDOGKEF_01890 9.81e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
LHDOGKEF_01891 1.24e-197 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
LHDOGKEF_01892 1.68e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHDOGKEF_01893 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
LHDOGKEF_01894 2.47e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHDOGKEF_01895 7.19e-202 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LHDOGKEF_01896 2.62e-198 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LHDOGKEF_01897 1.8e-124 yobS - - K - - - Bacterial regulatory proteins, tetR family
LHDOGKEF_01898 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LHDOGKEF_01899 6.9e-220 - - - - - - - -
LHDOGKEF_01900 0.0 - - - M - - - Rib/alpha-like repeat

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)